Transcranial magnetic stimulation circuit structure outputting paired pulses

Abstract

The utility model relates to a transcranial magnetic stimulation circuit structure outputting paired pulses, which comprises a power supply, an inductance coil, a control switch, a first capacitor, a thyristor and a second capacitor, and is characterized in that the power supply and the inductance coil are connected in parallel to form a charging circuit, the first capacitor is connected between the power supply and the second capacitor, and the control switch is connected to the charging circuit; the control switch is located between the first capacitor and the second capacitor, the control switch controls the power supply to charge the second capacitor, the thyristor is connected between the second capacitor and the inductance coil in series, and the second capacitor, the thyristor and the inductance coil form a circuit. A generated sine pulse signal passes through a changing magnetic field generated by an inductance coil to generate a stimulation current in a transcranial mode, and magnetic stimulation is completed.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a transcranial magnetic stimulation circuit structure that outputs paired pulses. Background Art

[0002] Transcranial Magnetic Stimulation (TMS) is a non-invasive biostimulation technology. During treatment or research, the stimulation coil is placed on the patient's head, with the center aligned with the treatment site. A high-voltage pulse is applied to the coil, causing the coil to generate a magnetic field. The magnetic field passes through the skin and skull, generating an induced current in the brain's nerve tissue, changing the threshold and membrane potential of intracranial nerve cells, thereby regulating nerve metabolism and electrophysiological activity. According to the different TMS stimulation pulses, TMS can be divided into three stimulation modes: Single-pulse TMS (sTMS): sTMS is manually controlled to output arrhythmic pulses, and can also stimulate multiple stimuli, but the stimulation interval is longer (for example, 10 seconds), and is mostly used for routine electrophysiological examinations. Double-pulse TMS (pTMS): pTMS continuously gives two stimuli of different intensities at the same stimulation site at very short intervals, or uses two stimulators at two different sites (also known as double-coil TMS, dTMS), which is mostly used to study the facilitation and inhibition of nerves. Repetitive TMS (rTMS): rTMS is divided into high-frequency and low-frequency types. The device is required to deliver slow-rhythm low-frequency or fast-rhythm high-frequency rTMS at the same stimulation site.

[0003] For double-pulse TMS (pTMS), the first TMS is usually called the conditioned stimulus (CS) and the second TMS is called the test stimulus (TS). Whether it produces a facilitative or inhibitory cortical effect depends on the stimulation intensity of the CS / TS and the interstimulus interval (ISI) between the two pulses, which is usually a time interval of ms. Because the ISI between the two pulses is extremely short, the TMS device needs to charge and discharge quickly in a very short time, and the power supply cannot fully charge the energy storage capacitor, resulting in the intensity of the second pulse being lower than the intensity of the first pulse, and the expected intensity of stimulation cannot be achieved. Therefore, how to meet the power requirements of the second pulse within the stimulation interval is a problem that needs to be solved urgently. Utility Model Content

[0004] In view of this, the present application proposes a transcranial magnetic stimulation circuit structure that outputs paired pulses, which can meet the power requirements of subsequent circuits and complete the output of paired pulses.

[0005] According to one aspect of the present application, there is provided a transcranial magnetic stimulation circuit structure for outputting paired pulses, comprising: a power supply, an inductor coil, a control switch, a first capacitor, a thyristor, and a second capacitor;

[0006] The power supply forms a charging circuit by connecting the second capacitor in parallel with the inductor;

[0007] The first capacitor is connected between the power supply and the second capacitor, and the control switch is connected and arranged on the charging circuit, located between the first capacitor and the second capacitor, and the control switch controls the power supply to charge the second capacitor;

[0008] The thyristor is connected in series between the second capacitor and the inductor.

[0009] In a possible implementation, the method further includes: a first resistor;

[0010] The first resistor is connected in series between the first capacitor and the second capacitor.

[0011] In a possible implementation manner, the capacitance of the first capacitor is greater than the capacitance of the second capacitor.

[0012] In a possible implementation, the capacitor voltage of the second capacitor is in the range of 1200V-2000V.

[0013] In a possible implementation manner, the control switch is disconnected, and the power supply charges the first capacitor;

[0014] The control opening is closed, the thyristor is not turned on, and the power supply charges the second capacitor;

[0015] The control switch is turned off, and the thyristor is turned on, and the second capacitor, the inductor and the thyristor form a series resonant circuit.

[0016] The beneficial effect of the transcranial magnetic stimulation circuit structure for outputting paired pulses in the embodiment of the present application is as follows: a first capacitor with high voltage, large capacity and high current is added after the input power supply. When the control switch is turned on to charge the second capacitor, the power stored in the first capacitor plus the power provided by the front-end power supply can meet the power requirements of the subsequent circuit and complete the output of paired pulses. For details, see Figure 1, the DC high-voltage power supply stores energy through the first capacitor. When the first capacitor completes energy storage, the control switch is controlled to open, and the second capacitor is charged through the first resistor (the thyristor is not turned on at this time); when the second capacitor is charged to the set voltage, the control circuit controls the control switch to turn off. When the control switch is turned off, the thyristor is controlled to turn on. At this time, the second capacitor, thyristor and inductor coil form a series resonant circuit. After the oscillation completes a cycle, the thyristor is turned off due to the circuit characteristics of the thyristor. A sinusoidal pulse signal generated by this circuit passes through the changing magnetic field generated by the inductor coil, which will generate a stimulation current in the transcranial cavity, completing a magnetic stimulation.

[0017] Other features and aspects of the present application will become apparent from the following detailed description of exemplary embodiments with reference to the attached drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The accompanying drawings, which are incorporated in and constitute a part of the specification, illustrate exemplary embodiments, features, and aspects of the present application and, together with the description, serve to explain the principles of the present application.

[0019] Figure 1 A schematic diagram showing the structure of a transcranial magnetic stimulation circuit that outputs paired pulses according to an embodiment of the present application. DETAILED DESCRIPTION

[0020] Various exemplary embodiments, features and aspects of the present application will be described in detail below with reference to the accompanying drawings. The same reference numerals in the accompanying drawings represent elements with the same or similar functions. Although various aspects of the embodiments are shown in the accompanying drawings, the drawings are not necessarily drawn to scale unless otherwise specified.

[0021] Among them, it needs to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the utility model or simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the utility model.

[0022] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0023] The word “exemplary” is used exclusively herein to mean “serving as an example, example, or illustration.” Any embodiment described herein as “exemplary” is not necessarily to be construed as preferred or advantageous over other embodiments.

[0024] In addition, in order to better illustrate the present application, numerous specific details are given in the following specific embodiments. It should be understood by those skilled in the art that the present application can also be implemented without certain specific details. In some examples, methods, means, components and circuits well known to those skilled in the art are not described in detail in order to highlight the subject matter of the present application.

[0025] See also Figure 1 The transcranial magnetic stimulation circuit structure for outputting paired pulses in an embodiment of the present application includes: a power supply 100, an inductor 400, a control switch 600, a first capacitor 200, a thyristor 500 and a second capacitor 300. The power supply 100 forms a charging circuit by connecting the second capacitor 300 in parallel with the inductor 400. The first capacitor 200 is connected in parallel between the power supply 100 and the second capacitor 300, and the control switch 600 is connected and arranged on the charging circuit, located between the first capacitor 200 and the second capacitor 300, and the control switch 600 controls the power supply 100 to charge the second capacitor 300, and the thyristor 500 is connected in series between the second capacitor 300 and the inductor 400.

[0026] In this embodiment, a first capacitor 200 with high voltage, large capacity and high current is added after the input power supply 100. When the control switch 600 is turned on to charge the second capacitor 300, the power stored in the first capacitor 200 plus the power provided by the front-end power supply 100 can meet the power requirements of the subsequent circuits and complete the output of paired pulses. Figure 1 , the DC high-voltage power supply 100 stores energy through the first capacitor 200. When the first capacitor 200 completes energy storage, the control switch 600 is controlled to be turned on, and the second capacitor 300 is charged through the first resistor 700 (the thyristor 500 is not turned on at this time); when the second capacitor 300 is charged to the set voltage, the control circuit controls the control switch 600 to be turned off. When the control switch 600 is turned off, the thyristor 500 is controlled to be turned on. At this time, the second capacitor 300, the thyristor 500 and the inductor 400 form a series resonant circuit. After the oscillation completes a cycle, the thyristor 500 is turned off due to the circuit characteristics of the thyristor 500. A sinusoidal pulse signal generated by this circuit will generate a stimulation current in the transcranial cavity through the changing magnetic field generated by the inductor 400, completing a magnetic stimulation.

[0027] In a specific embodiment, it also includes: a first resistor 700, which is connected in series between the first capacitor 200 and the second capacitor 300. When the first capacitor 200 charges the second capacitor 300, the current may be very large. The series resistor E1 can protect other components in the circuit.

[0028] In a specific embodiment, the capacitance of the first capacitor 200 is greater than the capacitance of the second capacitor 300, which is the result of charge transfer from a high potential to a low potential driven by a potential difference, so that the first capacitor 200 and the power supply 100 can charge the second capacitor 300 at the same time to meet the power requirement of the second pulse within the stimulation interval.

[0029] In a specific embodiment, the capacitor voltage of the second capacitor 300 is in the range of 1200V-2000V.

[0030] In a specific embodiment, the control switch 600 is disconnected, the power supply 100 charges the first capacitor 200, the control opening is closed, and the thyristor 500 is not turned on, the power supply 100 charges the second capacitor 300, the control switch 600 is disconnected, and the thyristor 500 is turned on, the second capacitor 300, the inductor 400 and the thyristor 500 form a series resonant circuit, and a sinusoidal pulse signal generated by this circuit will generate a stimulation current in the transcranial cavity through the changing magnetic field generated by L1, thereby completing a magnetic stimulation.

[0031] The embodiments of the present application have been described above, and the above description is exemplary, not exhaustive, and is not limited to the disclosed embodiments. Many modifications and changes will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The selection of terms used herein is intended to best explain the principles of the embodiments, practical applications, or improvements to the technology in the market, or to enable other persons of ordinary skill in the art to understand the embodiments disclosed herein.

Claims

1. A transcranial magnetic stimulation circuit structure for outputting paired pulses, characterized in that: include: A power supply, an inductor, a control switch, a first capacitor, a thyristor and a second capacitor; The power supply forms a charging circuit by connecting the second capacitor in parallel with the inductor; The first capacitor is connected between the power supply and the second capacitor, and the control switch is connected and arranged on the charging circuit, located between the first capacitor and the second capacitor, and the control switch controls the power supply to charge the second capacitor; The thyristor is connected in series between the second capacitor and the inductor.

2. The transcranial magnetic stimulation circuit structure for outputting paired pulses according to claim 1, characterized in that: Also includes: a first resistor; The first resistor is connected in series between the first capacitor and the second capacitor.

3. The transcranial magnetic stimulation circuit structure for outputting paired pulses according to claim 1, characterized in that: The capacitance of the first capacitor is greater than the capacitance of the second capacitor.

4. The transcranial magnetic stimulation circuit structure for outputting paired pulses according to claim 3, characterized in that: The capacitance voltage of the second capacitor is in the range of 1200V-2000V.

5. The transcranial magnetic stimulation circuit structure for outputting paired pulses according to any one of claims 1 to 4, characterized in that: The control switch is disconnected, and the power supply charges the first capacitor; The control opening is closed, the thyristor is not turned on, and the power supply charges the second capacitor; The control switch is turned off, and the thyristor is turned on, and the second capacitor, the inductor and the thyristor form a series resonant circuit.

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