Bone collagen purification device

By designing a collagen purification device, the limestone storage warehousing and gravel group are used to generate alkaline regulation liquid, combined with efficient mixing and automated control, the problems of low efficiency and low purity of traditional purification technology are solved, and high yield and high purity collagen purification is achieved, reducing costs and environmental pollution.

CN222789224UActive Publication Date: 2025-04-25KAILIDA (HENAN) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421536036.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-02
Publication Date
2025-04-25
Estimated Expiration
2034-07-02

AI Technical Summary

Technical Problem

The existing collagen purification technology is inefficient, the product purity is not high, the environmental control is unstable, and the equipment is inconvenient to maintain, resulting in high costs and environmental pollution.

Method used

A collagen purification device was designed, using limestone storage warehousing and gravel groups to achieve in-situ alkaline regulation fluid. Combined with efficient material mixing mechanism, precise automated control and convenient cleaning structure, the uniformity and thoroughness of the reaction were significantly improved.

Benefits of technology

Through this device, the yield and purity of collagen is significantly improved, the dependence of external chemical reagents is reduced, resources are saved, the precise regulation of the reaction environment is ensured, and environmental pollution and operation costs are reduced.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a bone collagen purification device which comprises a purification box, a limestone storage bin is arranged at the upper end of the purification box, a broken stone set is arranged in the limestone storage bin, a forked discharge port is formed in the lower end of the limestone storage bin, a screen plate is arranged at the discharge port connected to the purification box, and a filter screen is arranged at the lower end of the screen plate. Two mixing and stirring groups are arranged in the purification box, and the two mixing and stirring groups are arranged in opposite directions, the in-situ generation of the alkaline adjusting liquid is realized through the limestone storage bin and the gravel group, the dependence on external chemical reagents is reduced, the operation is simple, the cost is low, and the production efficiency is improved. Addition of lime is accurately controlled through the forked discharge port, so that resources are saved, accurate regulation and control of a reaction environment are ensured, and environmental protection and cost control are facilitated; the double reverse mixing and stirring groups not only enhance the mixing efficiency, but also effectively promote the uniform dispersion and sufficient reaction of the bone collagen and other reaction materials through the formation of a complex flow field.
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Description

Technical Field

[0001] The present application relates to the technical field of collagen processing, and in particular to a collagen purification device. Background Art

[0002] In the field of biological product processing, especially in the extraction and purification of collagen, traditional methods often face challenges such as low efficiency, low product purity, unstable environmental control and inconvenient equipment maintenance. As an important biomaterial, collagen is widely used in the pharmaceutical, cosmetic and food industries, and its purity and yield directly affect the quality and market competitiveness of the end product.

[0003] The current purification of collagen relies on the addition of chemical reagents to adjust the pH value and promote the dissolution of protein. This method is not only costly but also prone to environmental pollution. In addition, traditional equipment is often not sophisticated enough in terms of material mixing, pH value control and equipment cleaning, which affects the purification effect and production efficiency. Summary of the invention

[0004] The technical problem to be solved by the present application is to overcome the existing defects and provide a collagen purification device, which significantly enhances the uniformity and thoroughness of the reaction through an alkaline adjustment system, an efficient material mixing mechanism, precise automatic control and a convenient cleaning structure, effectively improves the yield and purity of the product, and can effectively solve the problems in the background technology.

[0005] To achieve the above-mentioned purpose, the present application provides the following technical solutions: a collagen purification device, comprising a purification box, a limestone storage bin is arranged at the upper end of the purification box, a crushed stone group is arranged in the limestone storage bin, a forked discharge port is arranged at the lower end of the limestone storage bin, a screen plate is arranged at the discharge port connected to the purification box, a mixing and stirring group is arranged inside the purification box, the number of the mixing and stirring groups is two, and the two groups of the mixing and stirring groups are arranged in opposite directions, a collagen guide and a clean water injection part are also arranged on one side of the purification box, and a pH meter for detecting the pH value of the liquid inside the purification box is arranged on the purification box.

[0006] As a preferred technical solution of the present application, the screen plate is hinged on the limestone storage bin, and guide shafts are provided on both sides of the screen plate, and the guide shafts are located in the arc groove of the limestone storage bin.

[0007] As a preferred technical solution of the present application, the other outlet of the bifurcated outlet is connected to a material storage member arranged on one side.

[0008] As a preferred technical solution of the present application, flow meters are provided on both the collagen guide member and the clean water injection member.

[0009] As a preferred technical solution of the present application, a cleaning assembly is arranged inside the purification box, and the cleaning assembly includes an injection assembly and a scraper group. The injection assembly is arranged around the purification box, and the scraper group is arranged at the upper end of the purification box.

[0010] As a preferred technical solution of the present application, the scraper group includes a cylinder group and a side wall scraper, and the side wall scraper is connected to the telescopic end of the cylinder group.

[0011] Compared with the prior art: the present application realizes in-situ generation of alkaline regulating liquid through limestone storage bin and crushed stone group, which not only reduces the dependence on external chemical reagents, but also accurately controls the addition of lime through the bifurcated discharge port, which not only saves resources but also ensures the precise regulation of the reaction environment, which is beneficial to environmental protection and cost control; the double-group reverse mixing and stirring group not only enhances the mixing efficiency, but also effectively promotes the uniform dispersion and full reaction of collagen and other reaction materials through the formation of complex flow fields, avoids local overheating or uneven reaction, and significantly improves the yield and purity of the product; the integrated pH meter monitors the pH inside the purification box in real time, and cooperates with the automatic control logic to automatically adjust the amount of lime water added according to the monitoring data to ensure that the entire purification process is maintained within the ideal pH range, thereby improving the stability of the process and the quality consistency of the product; the flow meters on the collagen guide and the clean water injection parts ensure the precise measurement of the collagen solution and clean water, avoid the waste of resources caused by excessive addition or the decrease in purification efficiency caused by insufficient addition, and improve the accuracy of the operation and the purity of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 This is a schematic diagram of the structure of this application;

[0013] Figure 2 This is the main view of this application;

[0014] Figure 3 for Figure 2 Schematic diagram of the AA section structure.

[0015] In the figure: 1. purification box, 2. limestone storage bin, 3. crushed stone group, 4. forked discharge port, 5. screen plate, 6. mixing and stirring group, 7. collagen guide part, 8. clean water injection part, 9. pH meter, 10. guide shaft, 11. storage part, 12. flow meter, 13. side wall scraper, 14. injection assembly, 15. scraper group, 16. cylinder group. DETAILED DESCRIPTION

[0016] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application (for the convenience of description and understanding, the following is Figure 2 All other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0017] See also Figure 1-3 The present application provides a technical solution: a collagen purification device, comprising a purification box 1, a limestone storage bin 2 is arranged at the upper end of the purification box 1, a crushed stone group 3 is arranged in the limestone storage bin 2, and a forked discharge port 4 is arranged at the lower end of the limestone storage bin 2.

[0018] The purification box 1 is used to contain the collagen extract and other reaction materials; it has good airtightness and pressure resistance so as to maintain ideal environmental conditions in different processing stages (such as reaction, stirring, separation, etc.).

[0019] Limestone silo 2 is used to store limestone particles. Limestone reacts with water to produce an alkaline environment (calcium hydroxide), which helps soften the raw materials, adjust the pH value, promote the dissolution of proteins and the removal of impurities.

[0020] The crushing group 3 crushes the larger pieces of limestone into fine particles or powder, which can increase the contact area between the limestone and water and accelerate its dissolution rate, thereby more effectively adjusting the pH value of the solution. It is also convenient to control the release amount of limestone and ensure the uniformity and controllability of the reaction.

[0021] The bifurcated discharge port 4 allows the lime water or dissolved limestone solution to be directed to different directions as needed. One flow direction may be used to continuously adjust the pH value in the purification box or participate in the reaction, and the other flow direction directly discharges excess lime water from the screen plate 5 or is used for other auxiliary treatment processes. The ratio of raw materials to lime water can be accurately controlled to optimize the purification efficiency.

[0022] A sieve plate 5 is provided at the discharge port connected to the purification box 1. A mixing and stirring group 6 is provided inside the purification box 1. There are two mixing and stirring groups 6, and the two mixing and stirring groups 6 are arranged in opposite directions.

[0023] The mixing and stirring group 6 is used to achieve uniform mixing of materials; each group of mixing and stirring groups 6 rotates in opposite directions to improve mixing efficiency; two groups of counter-rotating groups can generate a complex flow field, effectively breaking up vortices and dead zones in the liquid, and promoting full contact and uniform mixing of all materials including solid particles and liquid components. In the process of chemical reaction or material dissolution, it can accelerate the collision between molecules, increase the reaction rate, make the reaction more complete, and improve the yield and purity of the product.

[0024] A collagen guide 7 and a clean water injection part 8 are also provided on one side of the purification box 1 , and a pH meter 9 for detecting the pH value of the liquid inside the purification box 1 is provided on the purification box 1 .

[0025] The collagen guide 7 guides and controls the flow path of the collagen solution; during the purification process, it ensures that the extracted collagen solution is smoothly transferred to the purification box 1, reduces unnecessary stirring or disturbance, and protects the structural integrity of the collagen.

[0026] The clean water injection part 8 is used to inject clean water into the purification box 1 when necessary to dilute, clean or adjust the solution concentration and pH value; by accurately controlling the amount of clean water added, the chemical balance in the purification process is effectively managed, excessive salts and impurities are removed or adjusted to the optimal reaction conditions, thereby further optimizing the purification efficiency and product purity.

[0027] The pH meter 9 is an instrument for monitoring and adjusting the pH value of the liquid inside the purification box 1. Through real-time monitoring, the operator can instantly obtain the current pH value information of the purified liquid, and adjust the amount of lime water added, control the reaction process, or decide whether an additional neutralization step is needed, so as to ensure that the entire purification process is carried out within the predetermined ideal pH range and guarantee the quality of the final product.

[0028] Furthermore, the screen plate 5 is hinged to the limestone storage bin 2 , and guide shafts 10 are provided on both sides of the screen plate 5 , and the guide shafts 10 are located in the arc groove of the limestone storage bin 2 .

[0029] The screen plate 5 is connected to the limestone storage bin 2 in a hinged manner, so that the screen plate 5 can be flexibly opened and closed. When the screen plate 5 needs to be cleaned or maintenance work is performed, the operator can easily open the screen plate 5 without disassembling the entire purification system, which greatly improves the convenience and efficiency of maintenance.

[0030] The guide shaft 10 is not only a track for its opening and closing movement, but also ensures the stability and accuracy of the screen plate 10 during movement, avoiding wear or jamming problems that may be caused by direct friction.

[0031] Furthermore, the other outlet of the bifurcated outlet 4 is connected to the storage member 11 arranged on one side.

[0032] Furthermore, the collagen guide member 7 and the clean water injection member 8 are both provided with flow meters 12 .

[0033] The flowmeter 12 can accurately measure the flow of the collagen solution passing through the collagen guide 7 and the clean water added through the clean water injection piece 8, so that these operations can be performed accurately, avoiding the problem of excess or deficiency, and improving the purification efficiency and product purity.

[0034] Furthermore, a cleaning assembly is provided inside the purification box 1 , and the cleaning assembly includes a spray assembly 14 and a scraper assembly 15 . The spray assembly is provided around the purification box 1 , and the scraper assembly 15 is provided at the upper end of the purification box 1 .

[0035] The spray assembly 14 emits a cleaning solution (such as clean water or a special cleaning agent) into the interior of the box through a high-pressure nozzle. The nozzle covers every corner and surface of the purification box 1 to ensure that there is no dead angle in the cleaning and effectively remove the residues, sediments and microorganisms attached to the box wall and internal structure. The spray action can be set to a variety of modes such as circulation and pulse to meet different cleaning needs and improve cleaning efficiency. The scraper group 15 is close to the curve of the box to ensure that all attached substances are removed to the maximum extent. With the use of the spray assembly, deep cleaning can be achieved.

[0036] Furthermore, the scraper assembly 15 includes a cylinder assembly 16 and a side wall scraper 13 , and the side wall scraper 13 is connected to the telescopic end of the cylinder assembly 16 .

[0037] The cylinder group 16 provides the necessary thrust to move the side wall scraper 13 along the side wall of the purification box 1. The movement speed and strength of the side wall scraper 13 can be flexibly controlled to meet different cleaning requirements. The side wall scraper 13 can fit the inner wall shape of the purification box 1 tightly. The edge of the side wall scraper 13 has a flexible sealing strip, which can scrape off dirt powerfully without damaging the box body, ensuring the long-term use performance of the purification box 1.

[0038] When in use: introduce the collagen extract and other materials into the purification box 1 through the collagen guide 7, open the bifurcated discharge port 4 below the limestone storage bin 2, add lime to the purification box 1 in a timely and appropriate amount according to the display of the pH meter 9, adjust the pH value inside the purification box 1 until it reaches the ideal pH range, start the mixing and stirring group 6, set a suitable stirring speed to ensure that the materials are fully mixed without destroying the protein structure, add a suitable amount of clean water through the clean water injection part 8 according to the reaction situation, adjust the solution concentration or further neutralize, continuously monitor the temperature, pressure and pH value inside the purification box 1, and adjust the operating parameters in time to maintain the best purification conditions. Gradually slow down and stop the work of the mixing and stirring group 6 to avoid sudden shutdown causing solution turbulence, and safely transfer the purified solution to the next process or storage container through the discharge port. After the purification cycle is completed, use the cleaning component for comprehensive cleaning, open the injection component 14, select a suitable cleaning mode, and activate the cylinder group 16 to drive the side wall scraper 13 to scrape, and complete the deep cleaning of the inside of the box.

[0039] Although the embodiments of the present application have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present application, and that the scope of the present application is defined by the appended claims and their equivalents.

Claims

1. A collagen purification device, comprising a purification box (1), characterized in that: The upper end of the purification box (1) is provided with a limestone storage bin (2), a crushed stone group (3) is provided in the limestone storage bin (2), a bifurcated discharge port (4) is provided at the lower end of the limestone storage bin (2), a screen plate (5) is provided at the discharge port connected to the purification box (1), a mixing and stirring group (6) is provided inside the purification box (1), the number of the mixing and stirring groups (6) is two, and the two mixing and stirring groups (6) are arranged in opposite directions, a collagen guide member (7) and a clean water injection member (8) are also provided on one side of the purification box (1), and a pH meter (9) for detecting the pH value of the liquid inside the purification box (1) is provided on the purification box (1).

2. A collagen purification device according to claim 1, characterized in that: The screen plate (5) is hinged on the limestone storage bin (2), and guide shafts (10) are provided on both sides of the screen plate (5), and the guide shafts (10) are located in the arc groove of the limestone storage bin (2).

3. The collagen purification device according to claim 1, characterized in that: The other outlet of the bifurcated outlet (4) is connected to a material storage member (11) arranged on one side.

4. The collagen purification device according to claim 1, characterized in that: The collagen flow guide (7) and the clean water injection member (8) are both provided with flow meters (12).

5. The collagen purification device according to claim 1, characterized in that: A cleaning assembly is arranged inside the purification box (1), the cleaning assembly comprising a spray assembly (14) and a scraper assembly (15), the spray assembly is arranged around the purification box (1), and the scraper assembly (15) is arranged at the upper end of the purification box (1).

6. A collagen purification device according to claim 5, characterized in that: The scraper assembly (15) comprises a cylinder assembly (16) and a side wall scraper (13), wherein the side wall scraper (13) is connected to the telescopic end of the cylinder assembly (16).