Potassium glycyrrhizinate staphylococcus aureus control bacterium inspection device

By designing a control bacteria detection device for potassium glycyrrhizic acid salt Staphylococcus aureus, and using automatic reagent addition and mixing technology, the sample contamination problem caused by the unsolid plug seal is solved, the detection accuracy and efficiency are improved, and the workload of operators is reduced.

CN222825547UActive Publication Date: 2025-05-02XINJIANG TIANSHAN PHARM IND CO LTD
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Patent Information

Application Number
CN202420701257.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-08
Publication Date
2025-05-02
Estimated Expiration
2034-04-08

AI Technical Summary

Technical Problem

In the prior art, the sealing properties of the liquid culture medium with gusset triangular bottled pancreatic soybean beans are not firm, resulting in the risk of sample contamination, reducing the accuracy of the negative control group and the target microbiome, and requiring a large amount of microbial repetitive testing, which increases the workload of the operator.

Method used

A control bacteria detection device for potassium glycyrrhizic acid salt Staphylococcus aureus was designed, including a protective shell and a glass bottle. The glass bottle was equipped with a reagent addition tube 1 and a reagent addition tube 2. Through technical means such as separating components and servo motors, the automatic addition and mixing of reagents was achieved, reducing the risk of manual operation and sample contamination.

Benefits of technology

By reducing the risk of sample contamination, the accuracy of the negative control group and the target microbiome is improved, the workload of the operator is reduced, a large number of microbial repetitive detection work is avoided, and the inspection efficiency and practicality of the device are improved.

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Abstract

The utility model relates to the technical field of control bacterium inspection, in particular to a potassium glycyrrhizinate staphylococcus aureus control bacterium inspection device which comprises a protective shell and a glass bottle, a transparent protective cover plate is hinged to the upper end of the protective shell, a positioning block is arranged at the side end of the glass bottle, anti-slip lines are arranged at the side end of the glass bottle, and the transparent protective cover plate is hinged to the upper end of the glass bottle. A first reagent adding pipe is arranged above the glass bottle, and a second reagent adding pipe is arranged above the first reagent adding pipe. The reagent adding tube I and the reagent adding tube II are additionally arranged on the glass bottle of the inspection device for the potassium glycyrrhizinate staphylococcus aureus control bacteria, so that a worker does not need to repeatedly open a silica gel plug to add a reagent during inspection work, the risk that a sample is polluted is reduced, and the inspection efficiency is improved. Therefore, the accuracy of a negative control group and a target microbiome is improved, the workload of operators is reduced, and a large amount of repeated detection work of microorganisms is avoided.
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Description

Technical Field

[0001] The utility model relates to the technical field of controlled bacteria inspection, in particular to a potassium glycyrrhizinate yellow Staphylococcus aureus controlled bacteria inspection device. Background Art

[0002] In the microbial limit test of potassium glycyrrhizinate, samples often fail to meet the standards. The quality department conducts segmented investigations on the reasons for failure. On the one hand, the production department investigates the problems in the easily contaminated links of the workshop production, and on the other hand, investigates whether there is a risk of contamination in the negative control of microorganisms and the control group of the target microorganism. The negative control is used to verify the negative results of the culture and inspection methods. If the target microorganism does not appear in the negative control group, it means that the invisible results of the culture or detection method are reliable. The final analysis of the cause showed that the negative control was a stoppered triangular bottle of pancreatic casein soy peptone liquid culture medium. The stopper was not tightly sealed, and there was a risk of sample contamination, which reduced the accuracy of the negative control group and the target microorganism group. A large amount of microbial repetitive testing was required, which increased the workload of operators. Therefore, in order to solve the above problems, we proposed a potassium glycyrrhizinate Staphylococcus aureus control bacteria inspection device. Utility Model Content

[0003] 1. Technical issues to be resolved

[0004] In view of the deficiencies in the prior art, the utility model provides a potassium glycyrrhizinate Staphylococcus aureus control bacteria inspection device, which solves the technical problem that the negative control is originally a tryptic soy peptone liquid culture medium in a stoppered triangular bottle, the stopper is not firmly sealed, there is a risk of sample contamination, and thus the accuracy of the negative control group and the target microbial group is reduced, a large amount of microbial repetitive detection work is required, and the workload of operators is increased.

[0005] (II) Technical solution

[0006] In order to achieve the above objectives, the present invention is implemented through the following technical solutions:

[0007] The potassium glycyrrhizinate yellow Staphylococcus aureus control bacteria inspection device comprises a protective shell and a glass bottle, wherein the upper end of the protective shell is hingedly mounted with a transparent protective cover plate, the side end of the glass bottle is provided with a positioning block, the side end of the glass bottle is provided with an anti-slip pattern, a reagent adding tube 1 is provided above the glass bottle, a reagent adding tube 2 is provided above the reagent adding tube 1, and a silicone plug is provided above the reagent adding tube 2; the silicone plug is made of silicone;

[0008] The lower sections of the inner walls of the reagent addition tube 1 and the reagent addition tube 2 are both provided with a partition component, and the partition component includes a liquid separation plate 1 and a liquid separation plate 2, the upper end of the liquid separation plate 1 is symmetrically provided with two diversion holes 1, the upper end of the liquid separation plate 1 is symmetrically provided with two arc-shaped slide grooves, the upper end of the liquid separation plate 2 is symmetrically provided with two diversion holes 2, the upper end of the liquid separation plate 2 is fixedly provided with two sliders, the side end of the liquid separation plate 2 is fixedly provided with a paddle, and the side ends of the reagent addition tube 1 and the reagent addition tube 2 are both provided with a paddle slide groove; the slider is slidably installed in the arc-shaped slide groove, and the paddle is slidably installed in the paddle slide groove, and the liquid separation plate 1, the liquid separation plate 2 and the reagent addition tube 1, the reagent addition tube 2 are sealed with a sealing gasket, the diversion hole 1 and the slider are the same size, and the curvature of the arc-shaped slide groove is the deflection curvature between the slider and the diversion hole 1.

[0009] Preferably: a threaded butt joint pipe 1 is fixedly installed at the lower end of the reagent adding tube 1; the threaded butt joint pipe 1 is threadedly installed with the inner side of the glass bottle.

[0010] A threaded butt joint pipe 2 is fixedly installed at the lower end of the reagent adding pipe 2; the threaded butt joint pipe 2 is threadedly installed with the inner side of the reagent adding pipe 1.

[0011] Preferably: a servo motor is provided on the inner side wall of the protective shell, and a turntable 1 is rotatably mounted on the inner side wall of the protective shell; the rotating shaft of the turntable 1 is fixedly connected to the output shaft of the servo motor.

[0012] A second turntable is fixedly installed above the first turntable; the second turntable and the first turntable share the same rotating shaft.

[0013] The upper end of the turntable 1 is provided with a plurality of limit grooves at equal angles, and the upper end of the turntable 2 is provided with a plurality of positioning holes; each positioning hole is opened corresponding to the limit groove, the positioning block is snap-fitted and installed in the positioning hole, and the glass bottle is sleeved and installed in the limit groove.

[0014] (III) Beneficial effects

[0015] 1. By adding reagent addition tube 1 and reagent addition tube 2 to the glass bottle of the potassium glycyrrhizinate Staphylococcus aureus control bacteria inspection device, it is no longer necessary for staff to repeatedly open the silicone plug to add reagents during inspection, thereby reducing the risk of sample contamination, thereby improving the accuracy of the negative control group and the target microbial group, and also reducing the workload of operators, avoiding a large amount of repetitive microbial testing.

[0016] Second, by installing rotating turntable 1 and turntable 2 in the protective shell of the potassium glycyrrhizinate Staphylococcus aureus control bacteria inspection device, the positive control tube, the negative control tube and multiple groups of sample tubes to be tested can be placed in at the same time during the inspection. The rotation accelerates the mixing reaction between the reagent and the sample, and multiple groups of inspections improve the inspection efficiency, thereby effectively improving the practicability of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The above description is only an overview of the technical solution of the utility model. In order to more clearly understand the technical means of the utility model and implement it according to the contents of the specification, the following is a detailed description of the preferred embodiments of the utility model in conjunction with the accompanying drawings.

[0018] Figure 1 This is the overall structural diagram of the utility model of the potassium glycyrrhizinate Staphylococcus aureus control bacteria detection device;

[0019] Figure 2 This is a structural diagram of the utility model of the potassium glycyrrhizinate yellow Staphylococcus aureus control bacteria detection device;

[0020] Figure 3 This is a structural diagram of the installation of a reagent adding tube of the utility model;

[0021] Figure 4 This is a structural diagram of the reagent adding tube of the utility model;

[0022] Figure 5 This is a structural diagram of the partition component of the utility model.

[0023] Legend: 1. Protective shell; 11. Transparent protective cover; 12. Servo motor; 13. Turntable 1; 14. Turntable 2; 15. Limiting groove; 16. Positioning hole; 2. Glass bottle; 21. Positioning block; 22. Anti-slip pattern; 3. Reagent addition tube 1; 31. Threaded butt tube 1; 4. Reagent addition tube 2; 41. Threaded butt tube 2; 5. Partition assembly; 51. Dispensing plate 1; 52. Dispensing plate 2; 53. Diverter hole 1; 54. Arc-shaped slide; 55. Diverter hole 2; 56. Slider; 57. Pick; 58. Pick slide; 6. Silicone plug. DETAILED DESCRIPTION

[0024] The embodiment of the present application provides a potassium glycyrrhizinate Staphylococcus aureus control bacteria detection device, which effectively solves the technical problem that the negative control is originally a tryptic soy peptone liquid culture medium in a stoppered triangular bottle, the stopper is not firmly sealed, there is a risk of sample contamination, and thus the accuracy of the negative control group and the target microbial group is reduced, a large amount of microbial repetitive detection work is required, and the workload of operators is increased.

[0025] Example

[0026] like Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, the technical solution in the embodiment of the present application effectively solves the technical problem that the negative control is originally a tryptic soy peptone liquid culture medium in a stoppered triangular bottle, the stopper is not tightly sealed, there is a risk of sample contamination, and thus the accuracy of the negative control group and the target microbiome is reduced, a large number of microbial repetitive detection work is required, and the workload of the operator is increased. The overall idea is based on the following:

[0027] In view of the problems existing in the prior art, the utility model provides a glycyrrhizic acid potassium salt yellow Staphylococcus aureus control bacteria inspection device, comprising a protective shell 1 and a glass bottle 2, the upper end of the protective shell 1 is hingedly installed with a transparent protective cover plate 11, the side end of the glass bottle 2 is provided with a positioning block 21, the side end of the glass bottle 2 is provided with an anti-slip pattern 22, a reagent adding tube 1 3 is arranged above the glass bottle 2, a reagent adding tube 2 4 is arranged above the reagent adding tube 1 3, and a silicone plug 6 is arranged above the reagent adding tube 2 4; wherein, the silicone plug 6 The rubber plug 6 is made of silicone; the lower sections of the inner walls of the reagent adding tube 1 3 and the reagent adding tube 2 4 are both provided with a partition assembly 5, and the partition assembly 5 includes a liquid separation plate 1 51 and a liquid separation plate 2 52, the upper end of the liquid separation plate 1 51 is symmetrically provided with two diversion holes 1 53, the upper end of the liquid separation plate 1 51 is symmetrically provided with two arc-shaped slide grooves 54, the upper end of the liquid separation plate 2 52 is symmetrically provided with two diversion holes 2 55, the upper end of the liquid separation plate 2 52 is fixedly provided with two sliders 56, and the side end of the liquid separation plate 2 52 is fixed A paddle 57 is fixedly installed, and the side ends of the reagent adding tube 1 3 and the reagent adding tube 2 4 are both provided with a paddle slide groove 58; wherein, the slider 56 is slidably installed in the arc slide groove 54, and the paddle 57 is slidably installed in the paddle slide groove 58, and the liquid separation plate 1 51, the liquid separation plate 2 52 and the reagent adding tube 1 3, the reagent adding tube 2 4 are sealed with a sealing gasket, the diverter hole 1 53 and the slider 56 are of the same size, and the curvature of the arc slide groove 54 is the deflection curvature between the slider 56 and the diverter hole 1 53, and the reagent adding tube is pulled. The paddle 57 on the one 3 slides in the paddle slide groove 58 under the force of the paddle 57, and the paddle 57 drives the liquid separation plate 2 52 under the force, and the liquid separation plate 2 52 drives the slider 56 under the force, and the slider 56 slides in the arc-shaped slide groove 54 under the force, and the liquid separation plate 2 52 rotates to drive the diversion hole 2 55. When the diversion hole 2 55 rotates and aligns with the diversion hole 1 53, the lysis solution in the reagent addition tube 3 falls into the glass bottle 2, and then the paddle 57 on the reagent addition tube 2 4 is pulled, causing the premixed solution in the reagent addition tube 2 4 to fall into the glass bottle 2.

[0028] A threaded butt joint pipe 31 is fixedly installed at the lower end of the reagent addition tube 3; wherein, the threaded butt joint pipe 31 is threadedly installed with the inner side of the glass bottle 2; a threaded butt joint pipe 41 is fixedly installed at the lower end of the reagent addition tube 4; wherein, the threaded butt joint pipe 41 is threadedly installed with the inner side of the reagent addition tube 3, the sample to be tested is loaded into the glass bottle 2, and then the lysate is loaded into the reagent addition tube 3, and the premixed liquid is loaded into the reagent addition tube 4, the threaded butt joint pipe 41 is threadedly fixedly connected with the reagent addition tube 3, and then the silicone plug 6 is used to seal the reagent addition tube 4, and then the threaded butt joint pipe 31 is threadedly fixedly connected with the glass bottle 2.

[0029] A servo motor 12 is provided on the inner side wall of the protective shell 1, and a turntable 13 is rotatably installed on the inner side wall of the protective shell 1; wherein the rotation axis of the turntable 13 is fixedly connected to the output axis of the servo motor 12; a turntable 2 14 is fixedly installed above the turntable 13; wherein the turntable 2 14 and the turntable 1 13 share the same rotation axis; a plurality of limit grooves 15 are provided at equal angles on the upper end of the turntable 13, and a plurality of positioning holes 16 are provided on the upper end of the turntable 2 14; wherein each positioning hole 16 The positioning blocks 21 are snap-fitted into the positioning holes 16, and the glass bottles 2 are sleeved into the limiting grooves 15. The positioning blocks 21 on the glass bottles 2 are snap-fitted into the positioning holes 16, and the glass bottles 2 are placed in the limiting grooves 15. The transparent protective cover 11 is closed, and then the servo motor 12 is started. The output shaft of the servo motor 12 rotates to drive the turntable 13 and the turntable 2 14 to rotate. The turntable 13 and the turntable 2 14 rotate to drive the glass bottle 2 to rotate.

[0030] Working principle:

[0031] In the first step, when the potassium glycyrrhizinate yellow Staphylococcus aureus control bacteria inspection device is used, the sample to be tested is loaded into the glass bottle 2, and then the lysate is loaded into the reagent adding tube 1 3, and the premixed liquid is loaded into the reagent adding tube 2 4, and the threaded butt joint tube 2 41 is threadedly fixedly connected with the reagent adding tube 1 3, and then the reagent adding tube 2 4 is sealed with a silicone plug 6, and then the threaded butt joint tube 1 31 is threadedly fixedly connected with the glass bottle 2, and the installation is completed. When checking, pull the paddle 57 on the reagent adding tube 1 3, and the paddle 57 is forced to slide in the paddle slide groove 58, and the paddle 57 is forced to drive the liquid separation plate 2 52, and the liquid separation plate 2 52 is forced to drive the slider 56, and the slider 56 is forced to slide in the arc slide groove 54, and the separation The liquid pan 2 52 rotates to drive the diversion hole 2 55. When the diversion hole 2 55 rotates and is aligned with the diversion hole 1 53, the lysate in the reagent addition tube 1 3 falls into the glass bottle 2, and then the paddle 57 on the reagent addition tube 2 4 is pulled to cause the premixed liquid in the reagent addition tube 2 4 to fall into the glass bottle 2. By installing the reagent addition tube 1 3 and the reagent addition tube 2 4 on the glass bottle 2 of the potassium glycyrrhizinate yellow Staphylococcus aureus control bacteria inspection device, it is unnecessary for the staff to repeatedly open the silicone plug 6 to add the reagent during the inspection, thereby reducing the risk of sample contamination, thereby improving the accuracy of the negative control group and the target microbial group, and also reducing the workload of the operator, avoiding a large number of repetitive microbial detection work.

[0032] In the second step, when the potassium glycyrrhizinate yellow Staphylococcus aureus control bacteria inspection device is used, the positioning block 21 on the glass bottle 2 is then snapped into the positioning hole 16, the glass bottle 2 is placed in the limit groove 15, the transparent protective cover 11 is closed, and then the servo motor 12 is started, and the output shaft of the servo motor 12 rotates to drive the turntable 13 and the turntable 2 14 to rotate, and the turntable 13 and the turntable 2 14 rotate to drive the glass bottle 2 to rotate, and the rotating turntable 13 and the turntable 2 14 are installed in the protective shell 1 of the potassium glycyrrhizinate yellow Staphylococcus aureus control bacteria inspection device, so that when the inspection work is carried out, the positive control tube, the negative control tube and multiple groups of sample tubes to be tested can be put in at the same time, the rotation accelerates the mixing reaction between the reagent and the sample, and the inspection efficiency is improved by multiple groups, thereby effectively improving the practicability of the device.

[0033] Finally, it should be noted that: Obviously, the above embodiments are only examples for clearly explaining the present invention, and are not intended to limit the implementation methods. For ordinary technicians in the relevant field, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived from this are still within the scope of protection of the present invention.

Claims

1. A glycyrrhizic acid potassium salt Staphylococcus aureus control bacteria inspection device, comprising a protective shell (1) and a glass bottle (2), characterized in that: A transparent protective cover plate (11) is hingedly mounted on the upper end of the protective shell (1), a positioning block (21) is arranged on the side end of the glass bottle (2), an anti-slip pattern (22) is arranged on the side end of the glass bottle (2), a reagent adding tube 1 (3) is arranged above the glass bottle (2), a reagent adding tube 2 (4) is arranged above the reagent adding tube 1 (3), and a silicone plug (6) is arranged above the reagent adding tube 2 (4); Wherein, the silicone plug (6) is made of silicone material; The lower sections of the inner side walls of the reagent adding tube 1 (3) and the reagent adding tube 2 (4) are both provided with a partition assembly (5), and the partition assembly (5) comprises a liquid separation plate 1 (51) and a liquid separation plate 2 (52), the upper end of the liquid separation plate 1 (51) is symmetrically provided with two flow dividing holes 1 (53), the upper end of the liquid separation plate 1 (51) is symmetrically provided with two arc-shaped slide grooves (54), the upper end of the liquid separation plate 2 (52) is symmetrically provided with two flow dividing holes 2 (55), the upper end of the liquid separation plate 2 (52) is fixedly provided with two sliders (56), the side end of the liquid separation plate 2 (52) is fixedly provided with a paddle (57), and the side ends of the reagent adding tube 1 (3) and the reagent adding tube 2 (4) are both provided with a paddle slide groove (58); The slider (56) is slidably installed in the arc-shaped slide groove (54), the paddle (57) is slidably installed in the paddle slide groove (58), the liquid separation plate 1 (51), the liquid separation plate 2 (52) and the reagent addition tube 1 (3), the reagent addition tube 2 (4) are sealed by a sealing gasket, the diversion hole 1 (53) and the slider (56) are of the same size, and the curvature of the arc-shaped slide groove (54) is the deflection curvature between the slider (56) and the diversion hole 1 (53).

2. The glycyrrhizic acid potassium salt Staphylococcus aureus control bacteria inspection device according to claim 1, characterized in that: A threaded butt joint pipe (31) is fixedly mounted on the lower end of the reagent addition pipe (3); Wherein, the threaded butt joint pipe 1 (31) is threadedly mounted on the inner side of the glass bottle (2).

3. The glycyrrhizic acid potassium salt Staphylococcus aureus control bacteria inspection device according to claim 2, characterized in that: The lower end of the reagent addition tube 2 (4) is fixedly mounted with a threaded butt joint tube 2 (41); Wherein, the threaded butt joint pipe 2 (41) is threadedly installed on the inner side of the reagent addition pipe 1 (3).

4. The glycyrrhizic acid potassium salt Staphylococcus aureus control bacteria inspection device according to claim 3, characterized in that: The inner side wall of the protective shell (1) is provided with a servo motor (12), and the inner side wall of the protective shell (1) is rotatably mounted with a turntable (13); Wherein, the rotating shaft of the turntable 1 (13) is fixedly connected to the output shaft of the servo motor (12).

5. The glycyrrhizic acid potassium salt Staphylococcus aureus control bacteria inspection device according to claim 4, characterized in that: A second turntable (14) is fixedly mounted above the first turntable (13); Wherein, the second turntable (14) and the first turntable (13) share the same rotating shaft.

6. The glycyrrhizic acid potassium salt Staphylococcus aureus control bacteria inspection device according to claim 5, characterized in that: The upper end of the rotating disk 1 (13) is provided with a plurality of limit grooves (15) at equal angles, and the upper end of the rotating disk 2 (14) is provided with a plurality of positioning holes (16); Each of the positioning holes (16) is opened corresponding to the limiting groove (15), the positioning block (21) is snap-fitted and installed in the positioning hole (16), and the glass bottle (2) is sleeve-fitted and installed in the limiting groove (15).