Cell preservation device capable of monitoring in real time

Abstract

The utility model discloses a cell preservation device capable of monitoring in real time, which relates to the technical field of cell culture, and comprises a preservation box body, a detection mechanism and a refrigeration mechanism, a box door is arranged on one side of the preservation box body, the preservation box body is connected with the box door through a hinge, and a plurality of layers of placing plates are arranged in the preservation box body. The detection mechanism is arranged above the placement plate and is used for detecting cell activity, and the refrigeration mechanism is arranged on the outer side of the storage box body and is used for controlling the temperature in the storage box body. The detection mechanism is arranged, so that a user can detect cell activity in real time, subsequent operation on cells can be carried out in time, the cleaning assembly is arranged, soaking and decontamination operation on a probe are facilitated, pollution to the cell culture dish during detection is prevented, and the refrigeration mechanism is arranged, so that when cells are stored, the cell activity can be detected, and the detection efficiency is improved. The interior of the storage box body is always at lower temperature, so that the storage requirement of cells is met.

Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, in particular to a cell preservation device capable of real-time monitoring. Background Art

[0002] At present, the research on cells is also constantly developing. In order to ensure the activity of cells, preservation devices are usually used to preserve them, and the cells are placed in a low-temperature environment to reduce cell metabolism for long-term storage. However, the cell preservation devices in the prior art are not convenient for real-time detection of cell activity, and the data of cell activity cannot be observed intuitively. In addition, the cell culture dish needs to be taken out during the detection, which may easily cause contamination, and opening the door of the box multiple times will cause a large amount of cold air inside the box to leak out, resulting in a waste of resources and an increase in the load on the refrigeration equipment.

[0003] Based on this, a cell preservation device capable of real-time monitoring is now provided, which can eliminate the drawbacks of existing devices. Utility Model Content

[0004] The utility model aims to provide a cell preservation device capable of real-time monitoring, so as to solve the problem that it is inconvenient to detect cell activity in real time.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A cell storage device capable of real-time monitoring comprises a storage box, a box door is arranged on one side of the storage box, the storage box and the box door are connected by a hinge, a multi-layer placement board is arranged inside the storage box, and further comprises a detection mechanism and a refrigeration mechanism, the detection mechanism is arranged above the placement board and is used to detect cell activity, and the refrigeration mechanism is arranged outside the storage box and is used to control the temperature inside the storage box;

[0007] The detection mechanism includes a screw rod rotatably connected to the inner wall of the storage box, one end of the screw rod extends to the outside of the storage box and is connected to a transmission component, the outer side of the screw rod is threadedly connected to a slider, a plurality of electric push rods are fixedly installed on the lower end of the slider, the output end of the electric push rod is fixedly connected to a probe, and a cleaning component that cooperates with the probe is provided on one side of the placement plate.

[0008] Preferably, the refrigeration mechanism includes a refrigerator, which is arranged at the upper end of the preservation box, an air pump is arranged on one side of the refrigerator, the air pump and the refrigerator are connected by a connecting pipe, an air vent is arranged on one side of the preservation box, an air inlet pipe is arranged between the air pump and the air vent, and the output end of the refrigerator is connected to the preservation box through an air outlet pipe.

[0009] Preferably, the transmission assembly includes a sprocket fixedly connected to one end of the screw rod, the sprockets are connected by a chain belt, a motor is fixedly connected to one side of the sprocket located below, and a bracket is provided at the lower end of the motor.

[0010] Preferably, the cleaning assembly comprises a slide groove opened on the surface of the placement plate, a storage box is slidably arranged inside the slide groove, and a bolt is arranged on one side of the storage box.

[0011] Preferably, a handle is provided on one side of the door, and a display screen is provided on one side of the handle.

[0012] Preferably, a circular placement groove is provided on the upper surface of the placement plate, a plurality of arc-shaped plates are arranged inside the circular placement groove, and the arc-shaped plates are connected to the inner wall of the circular placement groove through springs.

[0013] Preferably, guide rods are provided on both sides of the sliding block, and the guide rods are fixedly connected to the inner wall of the storage box.

[0014] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0015] 1. The utility model is provided with a detection mechanism, so that the user can detect the cell activity in real time, without opening the box door multiple times, reducing resource waste, facilitating the subsequent operation of the cells in a timely manner, and providing a cleaning component to facilitate the soaking and decontamination of the probe to prevent contamination of the cell culture dish during detection;

[0016] 2. The utility model is provided with a refrigeration mechanism, and through the mutual cooperation among the refrigerator, the air pump, the vent, the air inlet pipe, the air outlet pipe and the storage box, the temperature inside the storage box is kept at a relatively low level when cells are stored, so as to meet the storage requirements of the cells and improve the detection efficiency;

[0017] 3. The utility model is provided with a placement circular groove, and with the cooperation of the arc plate and the spring, the cell culture dish can be limited, which is convenient for probe detection. A display screen is provided, so that the temperature condition and cell activity changes inside the storage box can be observed in real time, and the practicality is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a structural schematic diagram of one side of the utility model.

[0019] Figure 2 It is a structural schematic diagram of the other side of the utility model.

[0020] Figure 3 It is a structural schematic diagram of the utility model.

[0021] Figure 4It is a schematic diagram of the internal structure of the utility model.

[0022] Figure 5 It is a sectional view of the front view of the utility model.

[0023] Figure 6 For the utility model Figure 4 Enlarged view of point A in the middle.

[0024] Notes on figure numbers: 101, storage box; 102, box door; 103, placement plate; 104, display screen; 105, placement groove; 106, arc plate; 200, detection mechanism; 201, screw; 202, slider; 203, electric push rod; 204, probe; 205, chain belt; 206, motor; 207, storage box; 208, guide rod; 300, refrigeration mechanism; 301, refrigerator; 302, air pump; 303, vent; 304, air inlet pipe; 305, air outlet pipe. DETAILED DESCRIPTION

[0025] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments.

[0026] Example 1

[0027] In this embodiment, if Figure 1-Figure 6 As shown, the cell preservation device capable of real-time monitoring comprises a preservation box 101, a support base is symmetrically arranged at the lower end of the preservation box 101, and the support base plays a role of supporting the cell preservation device capable of real-time monitoring, a box door 102 is arranged on one side of the preservation box 101, the preservation box 101 and the box door 102 are connected by hinges, and the box door 102 is provided with a sealing strip matched with the preservation box 101, and by providing the sealing strip, the box door 102 can better form a seal with the preservation box 101 after closing, thereby avoiding the loss of cold air inside the preservation box 101 , to achieve the purpose of saving electric energy, a multi-layer placement plate 103 is arranged inside the preservation box 101, and also includes a detection mechanism 200 and a refrigeration mechanism 300. The detection mechanism 200 is arranged above the placement plate 103 and is used to detect cell activity. The refrigeration mechanism 300 is arranged on the outside of the preservation box 101 and is used to control the temperature inside the preservation box 101. Before the cell preservation device that can be monitored in real time is used, first check whether the device can be used normally, and then start the refrigerator 301 to keep the device in continuous refrigeration to ensure the normal progress of cell preservation;

[0028] The detection mechanism 200 includes a screw 201 rotatably connected to the inner wall of the storage box 101, one end of the screw 201 extends to the outside of the storage box 101 and is connected to a transmission component. The screw 201 is driven to rotate synchronously through the transmission component, and then the probe 204 is driven to contact the cell culture fluid, so as to achieve the purpose of detecting activity. The outer side of the screw 201 is threadedly connected to a slider 202, and a plurality of electric push rods 203 are fixedly installed at the lower end of the slider 202. The number of the electric push rods 203 is consistent with the number of the placement circular grooves 105, which is convenient for detection. The output end of the electric push rod 203 is fixedly connected to the probe 204, and a rotating chuck can be set between the electric push rod 203 and the probe 204 to facilitate the replacement of the probe 204. A cleaning component that cooperates with the probe 204 is set on one side of the placement plate 103. The cleaning component facilitates the cleaning of the probe 204 to prevent contamination.

[0029] Among them Figure 2 and Figure 4 As shown, the refrigeration mechanism 300 includes a refrigerator 301, which is arranged at the upper end of the storage box 101, and an air pump 302 is arranged on one side of the refrigerator 301. The air pump 302 and the refrigerator 301 are connected through a connecting pipe. A vent 303 is arranged on one side of the storage box 101, and an air inlet pipe 304 is arranged between the air pump 302 and the air vent 303. The outer sides of the air inlet pipe 304 and the air outlet pipe 305 are both provided with control valves to facilitate the control of air flow rate, the output end of the refrigerator 301 is connected to the storage box 101 through the outlet pipe 305. During the use of the cell storage device that can be monitored in real time, the refrigerator 301 continues to cool, and the air pump 302 is started to transmit the air inside the storage box 101 to the refrigerator 301 through the vent 303 and the inlet pipe 304. The refrigerator 301 converts the air into cold air, and then reaches the inside of the storage box 101 through the outlet pipe 305, thereby forming a reflux of cold air;

[0030] Among them Figure 3 As shown, the transmission assembly includes a sprocket fixedly connected to one end of the screw rod 201, and the sprockets are connected by a chain belt 205. A motor 206 is fixedly connected to one side of the sprocket located below. When the motor 206 is started, the corresponding sprocket is driven to rotate. Due to the transmission effect of the chain belt 205, the connected sprocket also rotates, thereby realizing the synchronous rotation of the screw rod 201 and improving the detection efficiency. A bracket is provided at the lower end of the motor 206, and the bracket is fixedly connected to the storage box 101.

[0031] Among them Figure 3-Figure 5As shown, the cleaning assembly includes a slide groove opened on the surface of the placement plate 103, which is convenient for adding cleaning liquid and installing and removing the storage box 207. The storage box 207 is slidably arranged inside the slide groove. The storage box 207 is provided with a cleaning liquid for treating the probe 204 to avoid reducing the detection accuracy of the probe 204 during the next cell activity detection. Bolts are arranged on one side of the storage box 207 to fix the position of the storage box 207.

[0032] Among them Figure 1 and Figure 2 As shown, a handle is provided on one side of the box door 102 to facilitate opening the box door 102, and a display screen 104 is provided on one side of the handle. The display screen 104 is electrically connected to the probe 204 to facilitate real-time monitoring of cell activity. A thermometer is provided above the placement plate 103 to facilitate intuitive observation of whether the temperature inside the storage box 101 changes;

[0033] Example 2

[0034] The difference from Example 1 is that Figure 3-Figure 5 As shown, a placement groove 105 is provided on the upper surface of the placement plate 103, which is convenient for the storage and use of cells and improves the overall practicality of the cell storage device capable of real-time monitoring. A plurality of arc-shaped plates 106 are provided inside the placement groove 105. The arc-shaped plates 106 are connected to the inner wall of the placement groove 104 through a spring, and are adapted to cell culture dishes of different sizes, and play a role of limiting and fixing.

[0035] Among them Figure 4 and Figure 6 As shown, guide rods 208 are provided on both sides of the slider 202, the slider 202 is slidably connected to the guide rods 208, and the guide rods 208 are fixedly connected to the inner wall of the storage box 101. The guide rods 208 play a limiting role to prevent the slider 202 from rotating during movement, thereby affecting the normal use of the device.

[0036] When in use, the refrigerator 301 in the cell preservation device that can be monitored in real time continues to cool, so that the temperature inside the preservation box 101 is maintained at a low value, which is convenient for the storage of cells. When the cell activity needs to be detected, the motor 206 controls the rotation of the screw 201, thereby driving the slider 202 to move, so that the electric push rod 203 and the probe 204 can move to the top of the test culture dish, and the electric push rod 203 is started, so that the probe 204 can contact the culture fluid, and then the data is transmitted to the display screen 104, which is convenient for the user to detect the condition of the cells in real time, and has good practicality.

[0037] The above is only a specific implementation of the present disclosure, but the protection scope of the present disclosure is not limited thereto. Any person skilled in the art who is familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present disclosure, which should be included in the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure should be based on the protection scope of the claims.

Claims

1. A cell storage device capable of real-time monitoring, comprising a storage box (101), a box door (102) being arranged on one side of the storage box (101), the storage box (101) and the box door (102) being connected via a hinge, and a multi-layer placement board (103) being arranged inside the storage box (101); It is characterized in that It also includes a detection mechanism (200), which is arranged above the placement plate (103) and is used to detect cell activity; A refrigeration mechanism (300), the refrigeration mechanism (300) being arranged outside the storage box (101) and used for controlling the temperature inside the storage box (101); The detection mechanism (200) comprises a screw rod (201) rotatably connected to the inner wall of the storage box (101), one end of the screw rod (201) extends to the outside of the storage box (101) and is connected to a transmission component, the outer side of the screw rod (201) is threadedly connected to a slider (202), a plurality of electric push rods (203) are fixedly mounted on the lower end of the slider (202), the output end of the electric push rod (203) is fixedly connected to a probe (204), and a cleaning component that cooperates with the probe (204) is provided on one side of the placement plate (103).

2. The cell storage device capable of real-time monitoring according to claim 1, characterized in that: The refrigeration mechanism (300) comprises a refrigerator (301), the refrigerator (301) being arranged at the upper end of a storage box (101), an air pump (302) being arranged on one side of the refrigerator (301), the air pump (302) and the refrigerator (301) being connected via a connecting pipe, an air vent (303) being arranged on one side of the storage box (101), an air inlet pipe (304) being arranged between the air pump (302) and the air vent (303), and an output end of the refrigerator (301) being connected to the storage box (101) via an air outlet pipe (305).

3. The cell storage device capable of real-time monitoring according to claim 1, characterized in that: The transmission assembly comprises a sprocket fixedly connected to one end of the screw rod (201), the sprockets are connected to each other via a chain belt (205), a motor (206) is fixedly connected to one side of the sprocket located at the bottom, and a bracket is provided at the lower end of the motor (206).

4. The cell storage device capable of real-time monitoring according to claim 1, characterized in that: The cleaning assembly comprises a slide groove opened on the surface of the placement plate (103), a storage box (207) is slidably arranged inside the slide groove, and a bolt is arranged on one side of the storage box (207).

5. The cell storage device capable of real-time monitoring according to claim 1, characterized in that: A handle is provided on one side of the box door (102), and a display screen (104) is provided on one side of the handle.

6. The cell storage device capable of real-time monitoring according to claim 1, characterized in that: A circular placement groove (105) is provided on the upper surface of the placement plate (103), and a plurality of arc-shaped plates (106) are arranged inside the circular placement groove (105). The arc-shaped plates (106) are connected to the inner wall of the circular placement groove (105) via springs.

7. The cell storage device capable of real-time monitoring according to claim 1, characterized in that: Guide rods (208) are provided on both sides of the sliding block (202), and the guide rods (208) are fixedly connected to the inner wall of the storage box (101).

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