Blood oxygen detection device combined with electrophysiology

Abstract

The utility model provides a blood oxygen detection device combined with electrophysiology, which solves the problem that the existing PPG (photoplethysmography) method is insufficient in blood oxygen saturation measurement precision, and mainly comprises an acquisition card which is integrated with a digital signal input interface and a synchronizing signal output interface, is connected with external biological equipment through the digital signal input interface to acquire corresponding ttl (blood oxygen saturation) signals, and is connected with the synchronizing signal output interface through the synchronizing signal output interface; signal synchronization with the electrophysiology equipment is realized through a synchronization signal output interface; the light source group comprises a plurality of LED excitation light sources with different wavelengths; the detector is a high-sensitivity photomultiplier; the power supply group comprises a light source driving circuit and a filter circuit, and the light source driving circuit is electrically connected with the light source group to supply power and receives a signal of the digital signal input interface to control the light source group to be switched on and off at the same time; and the filter circuit is electrically connected with the detector and is used for converting a current signal output by the detector into a voltage signal and carrying out low-pass filtering on the signal to provide a signal-to-noise ratio.

Description

Technical Field

[0001] The utility model relates to the technical field of blood oxygen detection devices, in particular to a blood oxygen detection device combined with electrophysiology. Background Art

[0002] Traditional blood oxygen detection equipment usually uses the PPG method to measure blood oxygen saturation. The PPG method calculates blood oxygen saturation by measuring the transmitted light or reflected light at the finger or earlobe. This method is easily affected by factors such as ambient light, skin color, and finger movement, resulting in low measurement accuracy. For example, in a dimly lit environment, the blood oxygen saturation measured by the PPG method may be low; for people with darker skin color, the blood oxygen saturation measured by the PPG method may also be low; in the case of finger movement, the blood oxygen saturation measured by the PPG method will also be affected.

[0003] To this end, we propose a blood oxygen detection device combined with electrophysiology to solve the above problems. Utility Model Content

[0004] The technical problem to be solved by the utility model is to overcome the defects of the prior art. The utility model proposes a blood oxygen detection device combined with electrophysiology, which can realize long-term detection of blood oxygen and electrical signal activity in specific brain areas by implanting optical fibers and electrodes in specific brain areas. Combined with drug administration or stimulation experiments, the response of specific brain areas to drugs or stimulation can be analyzed through real-time detection of blood oxygen and electrophysiological signals.

[0005] In order to solve the above technical problems, the technical solution adopted by the utility model is: a blood oxygen detection device combined with electrophysiology, comprising:

[0006] An acquisition card is integrated with a digital signal input interface and a synchronization signal output interface, which is connected to an external biological device through the digital signal input interface to acquire the corresponding TTL signal, and is synchronized with the electrophysiological device signal through the synchronization signal output interface;

[0007] A light source group, including LED excitation light sources of various wavelengths;

[0008] The detector is a high-sensitivity photomultiplier tube, which is used to detect the reflection intensity of the multiple LED excitation light sources;

[0009] The power supply group includes a light source driving circuit and a filtering circuit. The light source driving circuit is electrically connected to the light source group to supply power and simultaneously receives the signal from the digital signal input interface to control the switch of the light source group. The filtering circuit is electrically connected to the detector and is used to convert the current signal output by the detector into a voltage signal and simultaneously low-pass filter the signal to provide a signal-to-noise ratio.

[0010] Furthermore, the acquisition card, light source group, detector and power supply group are integrally packaged by a box body, and a light source driving circuit power supply and a filter circuit power supply are also provided in the box body. The light source driving circuit power supply is electrically connected to the light source driving circuit, and the filter circuit power supply is electrically connected to the filter circuit.

[0011] Furthermore, an exposed power switch interface is also provided on one side of the box body, and the power switch interface is electrically connected to the light source driving circuit power supply and the filter circuit power supply.

[0012] Furthermore, a detector gain knob and a light source power adjustment knob are integrated on the side of the box body. The detector gain knob is electrically connected to the filter circuit to control the detector sensitivity, and the light source power adjustment knob is electrically connected to the light source drive circuit to control the light intensity of the LED excitation light source.

[0013] Furthermore, a USB interface electrically connected to the acquisition card is also provided on the side of the box body.

[0014] Furthermore, the types of light sources in the light source group can be expanded to two or more.

[0015] Furthermore, the light source group includes two LED excitation light sources with central wavelengths of 660nm and 810nm respectively.

[0016] Compared with the prior art, the beneficial effects of the utility model include:

[0017] 1. It can detect blood oxygen concentration in a single brain region and characterize the metabolic status of a specific brain region.

[0018] 2. The device has abundant input and output interfaces, which is convenient for synchronization with other photoelectric detection equipment.

[0019] 3. Low cost. Due to the use of advanced optical design and algorithm optimization, the production cost and maintenance cost of blood oxygen concentration can be reduced.

[0020] 4. It can achieve long-term and high-precision blood oxygen detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] The disclosure of the present invention is described with reference to the accompanying drawings. It should be understood that the drawings are only for illustrative purposes and are not intended to limit the scope of protection of the present invention. In the accompanying drawings, the same reference numerals are used to refer to the same components. Among them:

[0022] Figure 1 Schematically shows a schematic diagram of the internal structure of a device proposed according to an embodiment of the utility model;

[0023] Figure 2Schematically shows a front panel diagram of a device proposed according to one embodiment of the utility model;

[0024] Figure 3 Schematically shows a rear panel diagram of a device proposed according to one embodiment of the utility model;

[0025] Figure 4 A schematic diagram of a device light source driving circuit according to an embodiment of the utility model is shown;

[0026] Figure 5 The figure schematically shows a filter circuit diagram of a device proposed according to an embodiment of the utility model.

[0027] Numbers in the figure: 1. USB interface; 2. Power supply of light source driving circuit; 3. Power switch interface; 4. Acquisition card; 5. Power supply of filter circuit; 6. Filter circuit board; 7. Light source one; 8. Light source driving circuit; 9. Power supply two; 10. Detector; 11. Reflected light detection port; 12. Detector gain knob; 13. Light source one power adjustment knob; 14. Light source two power adjustment knob; 15. Synchronous signal output interface; 16. Digital signal input interface one; 17. Light source output port; 18. Light source one switch; 19. Light source two switch; 20. Digital signal input interface two; 21. Digital signal input interface three. DETAILED DESCRIPTION

[0028] It is easy to understand that according to the technical solution of the utility model, without changing the essential spirit of the utility model, a person skilled in the art can propose a variety of interchangeable structural modes and implementation modes. Therefore, the following specific implementation modes and drawings are only exemplary descriptions of the technical solution of the utility model, and should not be regarded as the entirety of the utility model or as a limitation or restriction to the technical solution of the utility model.

[0029] According to one embodiment of the present invention, Figure 1-Figure 5 Shown.

[0030] like Figure 1-Figure 3 As shown, the specific structure of the detection device in the utility model includes:

[0031] The acquisition card 4 is integrated with a digital signal input interface and a synchronization signal output interface 15, and is connected to an external biological device through the digital signal input interface to acquire the corresponding ttl signal, and is synchronized with the electrophysiological device signal through the synchronization signal output interface 15;

[0032] A light source group, including LED excitation light sources of various wavelengths;

[0033] The detector 10 is a high-sensitivity photomultiplier tube, which is used to detect the reflection intensity of the multiple LED excitation light sources;

[0034] The power supply group includes a light source driving circuit 8 and a filtering circuit. The light source driving circuit 8 is electrically connected to the light source group to supply power and simultaneously receives the signal from the digital signal input interface to control the switch of the light source group. The filtering circuit is electrically connected to the detector 10 and is used to convert the current signal output by the detector 10 into a voltage signal and simultaneously performs low-pass filtering on the signal to provide a signal-to-noise ratio.

[0035] Specifically, in this embodiment, the light source group includes two LED excitation light sources with central wavelengths of 660nm and 810nm respectively. Figure 1 The middle ones are light source 1 7 and light source 2.

[0036] Similarly, the acquisition card 4, the light source group, the detector 10 and the power supply group are packaged as a whole by a box body, and the box body is also provided with a light source driving circuit power supply 2 and a filter circuit power supply 5, the light source driving circuit power supply 2 is electrically connected to the light source driving circuit 8, and the filter circuit power supply 5 is electrically connected to the filter circuit. The digital signal input interface 1 16, the digital signal input interface 2 20, and the digital signal input interface 3 21 are all the above-mentioned digital signal input interfaces.

[0037] like Figure 3 As shown, an exposed power switch interface 3 and a USB interface 1 electrically connected to the acquisition card 4 are also provided on one side of the rear panel of the box body. The power switch interface 3 is electrically connected to the light source driving circuit power supply 2 and the filter circuit power supply 5.

[0038] like Figure 2 As shown, the side of the box body is also integrated with a detector gain knob 12 and a light source power adjustment knob. The detector gain knob 12 is electrically connected to the filter circuit to control the sensitivity of the detector 10. The light source one power adjustment knob 13 and the light source two power adjustment knob 14 in the figure are both electrically connected to the light source driving circuit 8 to control the light intensity of the light source one 7 and the light source two respectively. Similarly, the light source output port 17 and the reflected light detection port 11 are also integrated on the front panel side of the box body. The light source output port 17 is used to input the optical fiber to a specific brain area of ​​an external organism. The reflected light detection port 11 receives the reflected light of the excitation light source, and inputs the reflected light intensity to the acquisition card 4 and calculates the blood oxygen detection conditions corresponding to the reflection conditions of different wavelengths. Similarly, the light source one switch 18 and the light source two switch 19 are used to control the on and off of the light source one 7 and the light source two.

[0039] For the light source driving circuit 8 in this embodiment, its specific circuit structure is as follows: Figure 4 As shown, the circuit principles of the light source 1 7 and the light source 2 are basically the same, and the specific circuit diagram of the light source driving control circuit is as follows Figure 5 shown.

[0040] The technical scope of the present invention is not limited to the contents described above. Those skilled in the art can make various deformations and modifications to the above embodiments without departing from the technical concept of the present invention, and these deformations and modifications should all fall within the protection scope of the present invention.

Claims

1. A blood oxygen detection device used in conjunction with electrophysiology, characterized in that: include: The acquisition card integrates a digital signal input interface and a synchronization signal output interface, connects to an external biological device through the digital signal input interface to acquire the corresponding TTL signal, and synchronizes with the electrophysiological device signal through the synchronization signal output interface; A light source group, including LED excitation light sources of various wavelengths; The detector is a high-sensitivity photomultiplier tube, which is used to detect the reflection intensity of the multiple LED excitation light sources; The power supply group includes a light source driving circuit and a filtering circuit. The light source driving circuit is electrically connected to the light source group to supply power and simultaneously receives the signal from the digital signal input interface to control the switch of the light source group. The filtering circuit is electrically connected to the detector and is used to convert the current signal output by the detector into a voltage signal and simultaneously low-pass filter the signal to provide a signal-to-noise ratio.

2. The blood oxygen detection device combined with electrophysiology according to claim 1, characterized in that: The acquisition card, light source group, detector and power supply group are integrally packaged by a box body, and a light source driving circuit power supply and a filter circuit power supply are also provided in the box body. The light source driving circuit power supply is electrically connected to the light source driving circuit, and the filter circuit power supply is electrically connected to the filter circuit.

3. The blood oxygen detection device combined with electrophysiology according to claim 2, characterized in that: An exposed power switch interface is also provided on one side of the box body, and the power switch interface is electrically connected to the light source driving circuit power supply and the filter circuit power supply.

4. The blood oxygen detection device combined with electrophysiology according to claim 2, characterized in that: The side of the box body is also integrated with a detector gain knob and a light source power adjustment knob. The detector gain knob is electrically connected to the filter circuit to control the detector sensitivity, and the light source power adjustment knob is electrically connected to the light source drive circuit to control the light intensity of the LED excitation light source.

5. The blood oxygen detection device combined with electrophysiology according to claim 2, characterized in that: The side of the box body is also provided with a USB interface electrically connected to the acquisition card.

6. The blood oxygen detection device combined with electrophysiology according to claim 1, characterized in that: The types of light sources in the light source group can be expanded to two or more.

7. The blood oxygen detection device combined with electrophysiology according to claim 3, characterized in that: The light source group includes two LED excitation light sources with central wavelengths of 660 nm and 810 nm respectively.

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