Liquid sample detection device

Abstract

The utility model provides a liquid sample detection device, which relates to the technical field of biological detection devices and comprises a base layer. Full contact and flowing of the liquid sample and the test element can be ensured by utilizing the opening structure; the blocking part can block liquid rushing into the testing groove through the opening structure, and instantaneous liquid impact through the opening structure can be blocked through the blocking part, so that a base layer can resist a large amount of liquid from entering the testing groove when entering a liquid sample, and the phenomenon of'flooding 'in the testing groove is avoided; the technical problems that in the prior art, in the sample testing process, strip deviation is prone to occurring, or a liquid sample directly flows into a non-testing area of a testing element, the accuracy of a detection result is affected, and sample leakage and environment pollution are possibly caused are solved.

Description

Technical Field

[0001] The utility model relates to the technical field of biological detection devices, in particular to a liquid sample detection device. Background Art

[0002] In the prior art, many sample testing devices need to take samples from a sample collector before testing, which is inefficient. Undesirable phenomena such as sample failure or flooding often occur during the test, affecting the accuracy of the test results and possibly causing sample leakage and environmental pollution. Utility Model Content

[0003] The purpose of the utility model is to provide a liquid sample detection device to alleviate the technical problems existing in the prior art that the sample test process is prone to not running or the liquid sample directly flows into the non-test area of ​​the test element, forming a "flooding" phenomenon, affecting the accuracy of the test results, and may cause sample leakage and environmental pollution.

[0004] The utility model provides a liquid sample detection device, comprising: a base layer;

[0005] The base layer is provided with a test slot for accommodating a test element, and one end of the base layer corresponding to the test slot is a closed structure, and the other end is an open structure;

[0006] The test slot comprises a bottom wall, and a blocking portion is provided at one end of the bottom wall close to the opening structure. The blocking portion can abut against the test element and is used to block liquid that flows into the test slot through the opening structure.

[0007] In a preferred embodiment of the present utility model, the blocking portion includes a blocking protrusion;

[0008] The test slot further comprises a side wall, the blocking protrusion is arranged extending along the surface of the bottom wall, the blocking protrusion abuts against the side wall, and the blocking protrusion is used to block instantaneous liquid impact;

[0009] In a preferred embodiment of the present utility model, the blocking portion further comprises a retaining groove;

[0010] The retaining groove is located at a side of the blocking protrusion away from the opening structure, the retaining groove abuts against the side wall, and the retaining groove is used to retain liquid that passes over the blocking protrusion.

[0011] In a preferred embodiment of the present invention, the blocking protrusion is inclined from one end close to the opening structure to the other end, and the height from one end of the blocking protrusion close to the opening structure to the bottom wall is greater than the height from the other end.

[0012] In a preferred embodiment of the present invention, one end of the blocking protrusion away from the opening structure extends into the interior of the retaining groove.

[0013] In a preferred embodiment of the utility model, the blocking protrusion extends in an arc shape toward a side surface of the opening structure;

[0014] The retaining groove extends in an arc shape on one side surface toward the blocking protrusion.

[0015] In a preferred embodiment of the utility model, a sealing protrusion is provided on the side wall;

[0016] The sealing protrusion can abut and seal against the side wall of the test element in the test slot to limit the liquid entering the test slot from flowing through the gap between the side wall and the test element.

[0017] In a preferred embodiment of the present invention, a plurality of sealing protrusions are provided, and the plurality of sealing protrusions are arranged at intervals along the extension direction of the side wall, wherein at least one sealing protrusion is located at the position of the retaining groove.

[0018] In a preferred embodiment of the present invention, the test slots are provided in a plurality of groups, the plurality of groups of the test slots are arranged at intervals along the base layer, and an independent partition structure is formed between any two adjacent test slots through the side wall.

[0019] In a preferred embodiment of the utility model, it also includes a covering layer and a protective cover;

[0020] The covering layer is connected to a side of the base layer away from the bottom wall, and the covering layer is used to form the test slot into a sealed test cavity;

[0021] The protective cover is sleeved on the outside of the base layer and the covering layer through one end of the opening structure, and the protective cover is respectively in contact with the base layer and the covering layer.

[0022] The utility model provides a liquid sample detection device, comprising a base layer, a cover layer and a microfluidic structure;

[0023] The base layer is provided with a test slot for accommodating a test element, and one end of the base layer corresponding to the test slot is a closed structure, and the other end is an open structure;

[0024] The microfluidic structure is connected to one end of the base layer having the opening structure, the covering layer covers the microfluidic structure, the base layer has a liquid inlet on a side away from the covering layer, and the microfluidic structure has an exhaust hole corresponding to the test slot, and the exhaust hole is arranged in a serpentine extension.

[0025] In a preferred embodiment of the present invention, the test slot includes a bottom wall, and a blocking portion is provided at one end of the bottom wall close to the opening structure. The blocking portion can abut against the test element, and the blocking portion is used to block the liquid that rushes into the test slot through the opening structure.

[0026] In a preferred embodiment of the utility model, it also includes a spacing portion;

[0027] The partitions correspond to the side walls of the test slot, and a receiving slot for clamping the test element is formed between any two adjacent partitions;

[0028] Each of the accommodating grooves is correspondingly provided with an exhaust hole.

[0029] In a preferred embodiment of the utility model, a buffer portion is also included;

[0030] The buffer portion includes an integrally formed abutment section and an inclined section, the abutment section is connected to the microfluidic structure, the inclined section is arranged at an inclination along one end of the abutment section to the liquid inlet, and the inclined section gradually increases from the distance between one end close to the abutment section and the test element to the other end of the abutment section.

[0031] The utility model provides a liquid sample detection device, comprising: a base layer; a test slot for accommodating a test element on the base layer, wherein one end of the base layer corresponding to the test slot is a closed structure, and the other end is an open structure; the open structure can ensure that the liquid sample and the test element are fully in contact and flow; the test slot comprises a bottom wall, and an end of the bottom wall close to the opening structure is provided with a blocking portion, the blocking portion can abut against the test element, and the blocking portion can form a barrier for liquid rushing into the test slot through the opening structure, and the instantaneous liquid impact through the opening structure can be blocked by the blocking portion, so that the base layer can resist a large amount of liquid from entering the test slot at the moment when the liquid sample enters, thereby avoiding the "flooding" phenomenon in the test slot, and alleviating the technical problems in the prior art that the sample test process is prone to not running or the liquid sample directly flows into the non-test area of ​​the test element, affecting the accuracy of the test result, and possibly causing sample leakage and environmental pollution. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] In order to more clearly illustrate the specific implementation methods of the utility model or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0033] Figure 1A schematic diagram of the overall appearance of a liquid sample detection device provided in an embodiment of the utility model;

[0034] Figure 2 A schematic diagram of the structure of the liquid sample detection device provided by the embodiment of the utility model after the base layer and the test element are assembled;

[0035] Figure 3 A schematic diagram of the structure of the base layer of the liquid sample detection device provided by the embodiment of the utility model;

[0036] Figure 4 A schematic diagram of a partially enlarged structure of a base layer of a liquid sample detection device provided in an embodiment of the utility model;

[0037] Figure 5 A schematic diagram of the structure of a liquid sample detection device provided in an embodiment of the utility model having a microfluidic structure;

[0038] Figure 6 A schematic diagram of the structure of the microfluidic structure and the base layer of the liquid sample detection device provided by the embodiment of the utility model forming an integral whole;

[0039] Figure 7 A schematic cross-sectional structure diagram of a liquid sample detection device having a microfluidic structure provided in an embodiment of the utility model;

[0040] Figure 8 A schematic diagram of a partially enlarged structure of a liquid sample detection device provided in an embodiment of the utility model having a microfluidic structure.

[0041] Icons: 100-base layer; 110-enclosed structure; 120-opening structure; 200-test element; 300-test slot; 310-bottom wall; 320-side wall; 400-blocking portion; 410-blocking protrusion; 420-retention groove; 500-sealing protrusion; 600-covering layer; 700-protective cover; 800-microfluidic structure; 810-vent; 900-liquid inlet; 1100-spacer; 1200-buffer; 1210-abutment section; 1220-inclined section. DETAILED DESCRIPTION

[0042] The technical solution of the utility model will be clearly and completely described below in conjunction with the embodiments. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0043] like Figure 1-Figure 8As shown, a liquid sample detection device provided in this embodiment includes: a base layer 100; a test slot 300 for accommodating a test element 200 is provided on the base layer 100, one end of the base layer 100 corresponding to the test slot 300 is a closed structure 110, and the other end is an open structure 120; the test slot 300 includes a bottom wall 310, and a blocking portion 400 is provided at one end of the bottom wall 310 close to the opening structure 120, and the blocking portion 400 can abut against the test element 200, and the blocking portion 400 is used to form a barrier to the liquid rushing into the test slot 300 through the opening structure 120.

[0044] It should be noted that the liquid sample detection device provided in this embodiment can adjust the fluidity of the liquid in the liquid sample detection process in corresponding stages, so as to ensure that the liquid sample can avoid impacting the test slot 300 on the basis of fully contacting and reacting with the test element 200, so as to ensure the accuracy of the test result and avoid the possibility of leakage of the liquid sample and pollution of the environment; specifically, the base layer 100 serves as the basic placement structure of the test element 200, one end of the base layer 100 forms a closed structure 110, and the other end is an open structure 120, which can ensure the contact of the liquid sample on the basis of protecting the test element 200; wherein, the test slot 300 can be selected based on the structure of the test element 200. Generally speaking, the test slot 300 and the test element 200 both adopt a rectangular structure, the test slot 300 can accommodate one test element 200, and the test element 20 0 can extend out of the test slot 300 and contact the liquid sample through the opening structure 120; further, the blocking portion 400 serves as a structure of the test slot 300 that hinders the flow of liquid. The blocking portion 400 is arranged on the bottom wall 310 of the test slot 300, and the blocking portion 400 abuts against the surface of the test element 200. When the base layer 100 drives the test element 200 to contact the liquid sample through the opening structure 120, the liquid sample will instantaneously impact the test element 200 and the test slot 300. In order to prevent the liquid sample from instantaneously impacting the test slot 300, the blocking portion 400 can form an obstruction buffer for the liquid sample, so that the liquid sample gradually undergoes a reaction test along one end of the test element 200 close to the opening structure 120, thereby alleviating the "flooding" phenomenon in the test slot 300 and avoiding a large amount of liquid samples from infecting the test element 200 in all directions, resulting in technical problems such as inaccurate test results.

[0045] Optionally, the test element 200 includes a test strip, which can be in various forms, such as immunological or chemical test forms, for detecting analytes in samples, such as drugs or related metabolites indicating physical conditions; when the test element 200 is a test strip, it can be made of absorbent or non-absorbent materials, and a test strip can use multiple materials for liquid transfer; one material of the test strip can be superimposed on another test strip material, for example, filter paper is superimposed on nitrocellulose; or, an area of ​​the test strip containing at least one material is located behind another area containing at least one different material; the test strip can achieve feedback by adding a solution of a substance that generates a signal to the surface of the application area or soaking one or more materials in a signal solution. The various areas of the test strip can be arranged as follows: A complete necessary test strip can include a sample application area and a test area. Usually, the liquid first contacts the sample application area and then flows to the test area based on capillary action. These areas are made of different materials and are connected together in the direction of liquid transfer.

[0046] Optionally, the liquid sample can be derived from a solid or semi-solid sample, including excrement, biological tissue and food samples, and the solid or semi-solid sample can be converted into a liquid sample by any appropriate method, such as mixing, crushing, macerating, incubating, dissolving or digesting the solid sample by enzymatic action in a suitable solution. The liquid sample can be derived from animals, plants and food samples, such as urine, saliva, blood and its components, spinal fluid, vaginal secretions, sperm, feces, sweat, secretions, tissues, organs, tumors, tissue and organ cultures, cell cultures and media from humans or animals, preferably, the biological sample is urine. Wherein, drugs of abuse (DOA) refer to the use of drugs for non-medical purposes. Abuse of these drugs can cause physical and mental damage, dependence, addiction and / or death. These drugs will be decomposed into different small molecules after being absorbed by the human body, and these small molecules are present in body fluids such as blood, urine, saliva, sweat or part of the body fluids. The above-mentioned small molecules exist; the test element 200 can test the abused drugs based on the test reaction and obtain feedback.

[0047] The liquid sample detection device provided in this embodiment includes: a base layer 100; a test slot 300 for accommodating a test element 200 is provided on the base layer 100; one end of the base layer 100 corresponding to the test slot 300 is a closed structure 110, and the other end is an open structure 120; the open structure 120 can ensure that the liquid sample is fully in contact with and flows through the test element 200; the test slot 300 includes a bottom wall 310, and one end of the bottom wall 310 close to the open structure 120 is provided with a blocking portion 400, which can abut against the test element 200, and the blocking portion 400 can pass through the test element 200. The liquid that rushes into the test slot 300 through the opening structure 120 forms a barrier, and the blocking portion 400 can block the instantaneous liquid impact through the opening structure 120, so that the base layer 100 can resist a large amount of liquid from entering the test slot 300 at the moment of entering the liquid sample, thereby avoiding the "flooding" phenomenon in the test slot 300, and alleviating the technical problems in the prior art that the sample test process is prone to not running or the liquid sample directly flows into the non-test area of ​​the test element 200, affecting the accuracy of the test results, and may cause sample leakage and environmental pollution.

[0048] On the basis of the above embodiments, further, in a preferred embodiment of the present utility model, the blocking portion 400 includes a blocking protrusion 410 and a retaining groove 420; the test slot 300 also includes a side wall 320, the blocking protrusion 410 is extended and arranged along the surface of the bottom wall 310, the blocking protrusion 410 abuts against the side wall 320, and the blocking protrusion 410 is used to block instantaneous liquid impact; the retaining groove 420 is located on the side of the blocking protrusion 410 away from the opening structure 120, the retaining groove 420 abuts against the side wall 320, and the retaining groove 420 is used to retain liquid that passes over the blocking protrusion 410.

[0049] In this embodiment, the blocking protrusion 410 can be raised along the surface of the bottom wall 310. When the test element 200 is placed in the test slot 300, the blocking protrusion 410 can form an abutment with the test element 200, that is, the blocking protrusion 410 serves as a structure at one end of the bottom wall 310 close to the opening structure 120. When the blocking protrusion 410 contacts the liquid sample through the opening structure 120 in the test slot 300, the liquid sample will instantly flow along the bottom wall 310 of the test slot 300 toward the direction of the closed structure 110. The blocking protrusion 410 can form a barrier for the liquid sample, so that the liquid sample cannot pass over the blocking protrusion 410 and enter the end of the test slot 300 close to the closed structure 110. When the contact between the liquid sample and the base layer 100 becomes stable, the liquid sample will gradually undergo a wetting reaction along the test element 200, thereby avoiding the possibility that the impact of the liquid sample may cause inaccurate feedback of the test element 200, and reducing the possibility of the test slot 300 causing a "flooding" phenomenon.

[0050] Furthermore, the retaining groove 420 is located on the side of the blocking protrusion 410 facing away from the outlet structure 120, and the retaining groove 420 can be recessed along the surface of the bottom wall 310, that is, when part of the liquid sample impacts the blocking protrusion 410 and passes over the blocking protrusion 410 along the gap between the blocking protrusion 410 and the test element 200, the retaining groove 420 can retain and store the part of the liquid sample in the retaining groove 420, thereby better ensuring that the liquid sample will not enter the interior of the test slot 300 and affect the normal use of the test element 200.

[0051] In a preferred embodiment of the present invention, the blocking protrusion 410 is inclined from one end close to the opening structure 120 to the other end, and the height from one end of the blocking protrusion 410 close to the opening structure 120 to the bottom wall 310 is greater than the height of the other end.

[0052] In a preferred embodiment of the present invention, one end of the blocking protrusion 410 away from the opening structure 120 extends into the interior of the retaining groove 420 .

[0053] In this embodiment, the blocking protrusion 410 is arranged adjacent to the retaining groove 420, that is, the end of the blocking protrusion 410 close to the opening structure 120 is the highest point, and the blocking protrusion 410 extends obliquely downward along the highest point until the blocking protrusion 410 extends to the lowest point of the retaining groove 420. The inclined blocking protrusion 410 can enable the liquid sample that passes over the blocking protrusion 410 to slowly enter the retaining groove 420 along the inclined surface, thereby alleviating the impact of the liquid sample; at the same time, the liquid sample that enters the retaining groove 420 also has an obstruction wall on the side of the retaining groove 420 away from the blocking protrusion 410, thereby better retaining and storing the liquid sample inside the retaining groove 420, thereby ensuring the stability of the flow of the liquid sample.

[0054] In a preferred embodiment of the present invention, a side surface of the blocking protrusion 410 extending toward the opening structure 120 is arc-shaped; a side surface of the retaining groove 420 extending toward the blocking protrusion 410 is arc-shaped.

[0055] In this embodiment, one end of the blocking protrusion 410 toward the opening structure 120 can extend in a crescent-shaped arc shape, and the crescent-shaped concave surface can be used to impact the liquid sample to better buffer and slow down the liquid sample; similarly, when part of the liquid sample passes over the blocking protrusion 410 and enters the retaining groove 420, the side wall 320 of the retaining groove 420 also extends in a crescent-shaped arc shape, and the crescent-shaped concave surface can be used to impact the liquid sample to further buffer and slow down the liquid sample, so as to maximize the guarantee that the liquid sample is blocked and retained at the blocking portion 400.

[0056] In a preferred embodiment of the present invention, a sealing protrusion 500 is provided on the side wall 320; the sealing protrusion 500 can abut and seal with the side wall 320 of the test element 200 located in the test slot 300 to limit the liquid entering the test slot 300 from flowing through the gap between the side wall 320 and the test element 200.

[0057] In the present embodiment, when the test element 200 is placed in the test slot 300, since it is impossible to ensure that the test element 200 is completely fitted with the side wall 320, a capillary gap may exist between the test element 200 and the side wall 320. The existence of the capillary gap may cause the liquid sample to enter the test slot 300 in advance and react with the test element 200, thereby causing inaccurate test results. By providing a sealing protrusion 500 on the side wall 320, the sealing protrusion 500 may adopt a pointed protrusion structure similar to a latch structure. The sealing protrusion 500 can reduce, prevent or restrict capillary flow. Since the sealing protrusion 500 protrudes from the side wall 320, when the test element 200 and the test slot 300 are in contact with each other, the sealing protrusion 500 may be in contact with the side wall 320. When the widths are equal or close, the test element 200 is placed into the test slot 300, and the sealing protrusion 500 can squeeze the test element 200, so that the side of the test element 200 forms a contact seal with the side wall 320 of the test slot 300, thereby preventing capillary flow. In addition, even if there is a capillary gap between the test element 200 and the side wall 320 of the test slot 300, the sealing protrusion 500 is in close pressure contact with the test element 200, and the liquid sample opened on the opening structure 120 is blocked at the sealing protrusion 500, so that the liquid sample cannot continue to flow downstream along the capillary gap, thereby avoiding the possibility of the liquid sample passing through the capillary gap contacting the test element 200 in advance.

[0058] In a preferred embodiment of the present invention, a plurality of sealing protrusions 500 are provided, and the plurality of sealing protrusions 500 are arranged at intervals along the extension direction of the side wall 320 .

[0059] In this embodiment, by providing a plurality of sealing protrusions 500 along the side wall 320, the capillary flow of the liquid sample inside the test slot 300 can be better avoided by using the plurality of sealing protrusions 500, the directional flow of the liquid sample is improved, and the accuracy of the test result can be better ensured. Preferably, at least one sealing protrusion 500 is located at the position of the retaining groove 420.

[0060] In a preferred embodiment of the present invention, multiple groups of test slots 300 are provided, and the multiple groups of test slots 300 are arranged at intervals along the base layer 100 , and any two adjacent test slots 300 form an independent separation structure through the side wall 320 .

[0061] In this embodiment, multiple test slots 300 are isolated from each other. One test slot 300 contains a test element 200. The requirement of simultaneously testing multiple liquid samples can be achieved through multiple test slots 300. At the same time, an independent separation structure is formed between any two adjacent test slots 300 through the side wall 320 to avoid mutual interference between the test elements 200 and cause misjudgment of the results.

[0062] In a preferred embodiment of the utility model, it also includes a covering layer 600 and a protective cover 700; the covering layer 600 is connected to the side of the base layer 100 away from the bottom wall 310, and the covering layer 600 is used to form a sealed test cavity for the test slot 300; the protective cover 700 is sleeved on the outside of the base layer 100 and the covering layer 600 through one end of the opening structure 120, and the protective cover 700 is respectively abutted against the base layer 100 and the covering layer 600.

[0063] Optionally, the base layer 100 may be made of a transparent material, or the cover layer 600 may be made of a transparent material. Preferably, the base layer 100 is made of a transparent material to facilitate observation of the test reaction of the test element 200 inside the test slot 300 .

[0064] In this embodiment, the side of the base layer 100 facing away from the bottom wall 310 of the test slot 300 is an open structure, and the covering layer 600 can be placed at the open structure of the base layer 100. The covering layer 600 can be used to fix the test element 200 in the test slot 300 to ensure that the test element 200 is fixed in the test slot 300, and can also ensure that the end of the test element 200 is exposed at the opening structure 120; the protective cover 700 can protect the test element 200 through one end of the opening structure 120, and can also prevent the base layer 100 and the covering layer 600 from being separated. In addition, the protective cover 700 can form an end seal for the tested test element 200 and the test slot 300 to avoid the possibility of liquid sample leakage and contamination of the environment after the test is completed.

[0065] like Figure 5-Figure 8 As shown, this embodiment provides a liquid sample detection device, including a base layer 100, a cover layer 600 and a microfluidic structure 800; the base layer 100 has a test slot 300 for accommodating a test element 200, and one end of the base layer 100 corresponding to the test slot 300 is a closed structure 110 and the other end is an open structure 120;

[0066] The microfluidic structure 800 is connected to one end of the base layer 100 having an opening structure 120, the covering layer 600 covers the microfluidic structure 800, and the base layer 100 has a liquid inlet 900 on the side facing away from the covering layer 600. The microfluidic structure 800 is provided with an exhaust hole 810 corresponding to the test slot 300, and the exhaust hole 810 is arranged in a serpentine shape.

[0067] The liquid sample detection device provided in this embodiment can be used as an independent product, or it can be combined with the blocking part 400 to form a combined product, that is, when the base layer is fixedly connected to the microfluidic structure 800, the microfluidic structure 800 can form a seal on the opening structure 120, and because there is a liquid inlet 900 for the liquid sample to flow in between the microfluidic structure 800 and the base layer 100, when the liquid sample contacts and flows with the test element 200 and the test slot 300 through the liquid inlet 900, the excess gas in the test slot 300 will be directly discharged through the exhaust hole 810, ensuring that a sufficient amount of liquid sample can enter the test slot 300, thereby ensuring sufficient contact between the test element 200 and the liquid sample; wherein, the exhaust holes 810 extending in a serpentine manner can better prevent the liquid sample that has entered the test slot 300 from being lost from the exhaust holes 810.

[0068] When the base layer has both the microfluidic structure 800 and the blocking portion 400, the blocking portion 400 serves as a structure that blocks the flow of liquid in the test slot 300. The microfluidic structure 800 can directly discharge excess gas in the test slot 300 along the exhaust hole 810. When the base layer 100 drives the test element 200 to contact the liquid sample through the liquid inlet 900, the liquid sample will instantaneously impact the test element 200 and the test slot 300. In order to prevent the liquid sample from instantaneously impacting the test slot 300, the blocking portion 400 can form an obstruction buffer for the liquid sample, so that the liquid sample gradually undergoes a reaction test along the end of the test element 200 close to the liquid inlet 900, thereby alleviating the "flooding" phenomenon in the test slot 300 and preventing a large amount of liquid samples from infecting the test element 200 in all directions, leading to technical problems such as inaccurate test results.

[0069] On the basis of the above embodiments, further, in a preferred embodiment of the utility model, a spacer 1100 is also included; the spacer 1100 corresponds to the side wall of the test slot 300, and a receiving groove for clamping the test element 200 is formed between any two adjacent spacers 1100; each receiving groove is correspondingly provided with an exhaust hole 810.

[0070] In a preferred embodiment of the utility model, a buffer portion 1200 is also included; the buffer portion 1200 includes an integrally formed abutment section 1210 and an inclined section 1220, the abutment section 1210 is connected to the microfluidic structure 800, the inclined section 1220 is arranged obliquely from one end of the abutment section 1210 to the liquid inlet 900, and the inclined section 1220 gradually increases from the distance between the test element 200 and one end close to the abutment section 1210 to the other end.

[0071] In this embodiment, the spacer 1100 can be arranged corresponding to the test slot 300. The accommodating groove formed by the spacer 1100 can form a clamping spacer arrangement at the end of the test element 200. The position where the accommodating groove abuts the microfluidic structure 800 has a buffer portion 1200. The buffer portion 1200 is arranged corresponding to the bottom wall 310 of the test slot 300, and the height of the abutting section 1210 is adapted to the height of the bottom wall 310. The inclined section 1220 can gradually contact the test element 200 with the liquid sample as the position of the liquid inlet 900 increases, thereby ensuring sufficient contact between the test element 200 and the liquid sample; it can also ensure that excess gas in the test slot 300 will be directly discharged through the exhaust hole 810.

[0072] It should be noted that the liquid sample detection device provided in this embodiment and the liquid sample detection device provided in the above embodiment can be independent products or combined to form a combined product. Since other technical effects of the liquid sample detection device provided in this embodiment are the same as those of the liquid sample detection device provided in the above embodiment, they will not be described in detail here.

[0073] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in this field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model.

Claims

1. A liquid sample detection device, characterized in that: include: Base (100); The base layer (100) is provided with a test slot (300) for accommodating a test element (200); one end of the base layer (100) corresponding to the test slot (300) is in a closed structure (110), and the other end is in an open structure (120); The test slot (300) comprises a bottom wall (310), and a blocking portion (400) is provided at one end of the bottom wall (310) close to the opening structure (120). The blocking portion (400) can abut against the test element (200), and the blocking portion (400) is used to block the liquid that rushes into the test slot (300) through the opening structure (120).

2. The liquid sample detection device according to claim 1, characterized in that: The blocking portion (400) comprises a blocking protrusion (410); The test slot (300) further comprises a side wall (320), the blocking protrusion (410) is arranged to extend along the surface of the bottom wall (310), the blocking protrusion (410) abuts against the side wall (320), and the blocking protrusion (410) is used to block instantaneous liquid impact.

3. The liquid sample detection device according to claim 2, characterized in that: The blocking portion (400) further includes a retaining groove (420); The retaining groove (420) is located on a side of the blocking protrusion (410) away from the opening structure (120), and the retaining groove (420) abuts against the side wall (320). The retaining groove (420) is used to retain liquid that passes over the blocking protrusion (410).

4. The liquid sample detection device according to claim 3, characterized in that: The blocking protrusion (410) is arranged obliquely from one end close to the opening structure (120) to the other end, and the height of the blocking protrusion (410) from one end close to the opening structure (120) to the bottom wall (310) is greater than the height of the other end.

5. The liquid sample detection device according to claim 4, characterized in that: One end of the blocking protrusion (410) away from the opening structure (120) extends into the interior of the retaining groove (420).

6. The liquid sample detection device according to claim 5, characterized in that: The blocking protrusion (410) extends in an arc shape on one side surface facing the opening structure (120); A side surface of the retaining groove (420) extending toward the blocking protrusion (410) is arc-shaped.

7. The liquid sample detection device according to claim 1, characterized in that: The test slot (300) further comprises a side wall (320), and a sealing protrusion (500) is provided on the side wall (320); The sealing protrusion (500) can abut and seal against the side wall (320) of the test element (200) located in the test slot (300) to limit the liquid entering the test slot (300) from flowing through the gap between the side wall (320) and the test element (200).

8. The liquid sample detection device according to claim 7, characterized in that: A plurality of the sealing protrusions (500) are provided, and the plurality of sealing protrusions (500) are arranged at intervals along the extension direction of the side wall (320).

9. The liquid sample detection device according to claim 8, characterized in that: The test slots (300) are provided in a plurality of groups, and the plurality of groups of the test slots (300) are arranged at intervals along the base layer (100), and an independent separation structure is formed between any two adjacent test slots (300) through the side wall (320).

10. The liquid sample detection device according to any one of claims 1 to 9, characterized in that: Also includes a covering layer (600) and a protective cover (700); The covering layer (600) is connected to a side of the base layer (100) facing away from the bottom wall (310), and the covering layer (600) is used to form the test slot (300) into a sealed test cavity; The protective sleeve (700) is sleeved on the outside of the base layer (100) and the cover layer (600) through one end of the opening structure (120), and the protective sleeve (700) is respectively in contact with the base layer (100) and the cover layer (600).

11. A liquid sample detection device, characterized in that: It includes a base layer (100), a cover layer (600) and a microfluidic structure (800); The base layer (100) is provided with a test slot (300) for accommodating a test element (200); one end of the base layer (100) corresponding to the test slot (300) is in a closed structure (110), and the other end is in an open structure (120); The microfluidic structure (800) is connected to one end of the base layer (100) having the opening structure (120); the covering layer (600) covers the microfluidic structure (800); a side of the base layer (100) facing away from the covering layer (600) has a liquid inlet (900); the microfluidic structure (800) is provided with an exhaust hole (810) corresponding to the test slot (300); and the exhaust hole (810) is arranged in a serpentine shape.

12. The liquid sample detection device according to claim 11, characterized in that: The test slot (300) comprises a bottom wall (310), and a blocking portion (400) is provided at one end of the bottom wall (310) close to the opening structure (120). The blocking portion (400) can abut against the test element (200), and the blocking portion (400) is used to block the liquid that rushes into the test slot (300) through the opening structure (120).

13. The liquid sample detection device according to claim 11 or 12, characterized in that: Also includes a spacer (1100); The partition (1100) corresponds to the side wall of the test slot (300), and a receiving slot for clamping the test element (200) is formed between any two adjacent partitions (1100); Each of the accommodating grooves is correspondingly provided with an exhaust hole (810).

14. The liquid sample detection device according to claim 13, characterized in that: Also includes a buffer portion (1200); The buffer portion (1200) comprises an integrally formed abutment section (1210) and an inclined section (1220); the abutment section (1210) is connected to the microfluidic structure (800); the inclined section (1220) is arranged in an inclined manner from one end of the abutment section (1210) to the liquid inlet (900); and the inclined section (1220) gradually increases from the distance between the test element (200) and one end close to the abutment section (1210) to the other end.

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