Multi-sample immunohistochemical detection plate
By designing a multi-sample immunohistochemistry detection plate, the problems of cross-contamination and insufficient control of traditional detection plate samples are solved, and efficient and flexible sample processing and experimental operations are achieved, which is suitable for the needs of high-throughput laboratories.
Patent Information
- Application Number
- CN202421587718.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-06
- Publication Date
- 2025-05-06
- Estimated Expiration
- 2034-07-06
AI Technical Summary
Traditional multi-sample detection plates have the problems of cross-contamination of samples and insufficient control of sample volume and reaction conditions, which limits their application in high-throughput and high-precision experiments.
A multi-sample immunohistochemical detection plate is designed, including a housing, base plate, detection plate mechanism, drainage tank, outlet hole and anti-slip washer. It adopts a modular design and an integrated scanning and identification system to provide additional protection and operational convenience through edge sealing and cover systems.
Improves the efficiency of sample processing and experimental flexibility, reduces the risk of sample cross-contamination, simplifies the daily maintenance and cleaning process of the equipment, and is suitable for the needs of high-throughput laboratories.
Smart Images

Figure CN222838072U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical devices, in particular to a multi-sample immunohistochemistry detection plate. Background Art
[0002] In modern biomedical research, experiments often require simultaneous analysis of multiple biological samples to explore and verify scientific hypotheses. For example, in cancer research, multiple detections of specific proteins or gene expression are often involved to identify disease mechanisms or treatment responses. Such experiments may involve detecting molecular changes in multiple cell lines or tissue samples, such as monitoring the expression of the RTN3 gene in multiple samples when studying cell stress responses. Traditional detection panels are mostly designed for single samples and cannot accommodate multiple samples for parallel processing, which limits the efficiency and scalability of the experiment.
[0003] Traditional multi-sample assay plates often face the problem of sample cross-contamination and insufficient control over sample amount and reaction conditions, which limits their application in high-throughput and high-precision experiments. Utility Model Content
[0004] 1. Technical issues to be resolved
[0005] The utility model aims to provide a multi-sample immunohistochemistry detection plate to solve the problem of sample cross contamination in the traditional multi-sample detection plate mentioned in the background technology.
[0006] (II) Technical solution
[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a multi-sample immunohistochemical detection plate, which includes a shell, a bottom plate, a detection plate mechanism, a drainage groove, a water outlet and an anti-skid gasket, the lower end of the shell is provided with a bottom plate, the upper end of the shell is provided with a detection plate mechanism, the upper end of the bottom plate is provided with a drainage groove, the lower end of the bottom plate is provided with a water outlet, the lower end of the bottom plate is provided with an anti-skid gasket, the detection plate mechanism includes an edge seal, the upper end of the shell is provided with several edge seals, and the shell provides a structural foundation and external protection The bottom plate enhances the stability of the overall structure and provides a solid foundation for the device. The detection plate mechanism accommodates and supports the simultaneous detection of multiple samples, making it possible to process a large number of samples. The drain groove is designed to collect and guide the liquid inside the device to prevent overflow and moisture. The drain hole allows the liquid in the drain groove to drain smoothly to prevent liquid accumulation and possible contamination. The non-slip gasket increases the grip of the device to prevent sliding or movement during use. The edge seal provides additional protection around the sample slot to prevent sample spillage or cross contamination.
[0008] Preferably, a marking plate is provided at the front end of the edge seal, and a barcode is provided on the marking plate. The marking plate is used to identify sample information and provide rapid sample identification and tracking. The barcode provides necessary label information for the automation system.
[0009] Preferably, a sample slot is provided inside the edge seal, and a plurality of micropores are provided on the sample slot. The sample slot is used to accommodate various samples and is suitable for different experimental requirements. The micropores are tiny holes provided in the sample slot and are used to enhance the accuracy and efficiency of sample processing.
[0010] Preferably, a cover plate is provided at the upper end of the edge seal, a handle is provided at the upper edge of the cover plate, and a lock is provided at the lower end of the cover plate. The cover plate covers the sample slot to provide physical protection and prevent contamination. The lock is used to fix the cover plate to ensure the safety and stability of the sample during the detection process.
[0011] Preferably, a connecting rod is provided at the lower end of the handle, and a movable block is provided at the lower end of the connecting rod. The connecting rod connects the handle and the movable block to transmit power for opening or locking the cover.
[0012] Preferably, a movable spring is provided at the left end of the movable block, and a latch is provided at the right end of the movable block. The movable spring provides necessary tension for the locking system to help the handle and the locking mechanism to operate smoothly. The latch is inserted into the corresponding socket to provide a fixed point for locking the cover.
[0013] Preferably, a plug hole is provided on the edge sealing at a position corresponding to the plug pin.
[0014] Compared with the prior art, the beneficial effects of the utility model are:
[0015] 1. The multi-sample immunohistochemistry test panel improves the efficiency of sample processing because it can process multiple samples at the same time, reducing the time and labor required for processing a single sample, speeding up the experimental process, and making laboratory work more efficient. This design is especially important for high-throughput laboratories because they need to process a large number of samples to ensure fast and accurate data output. In addition, the integrated scanning and identification system reduces human errors and improves the accuracy of sample tracking and data management by automatically reading sample barcodes;
[0016] 2. The modular design of the multi-sample immunohistochemistry test panel allows for rapid configuration and customization, enabling it to be flexibly adjusted according to different test requirements and sample types. The independent sample slots and personalized cover system between modules allow each sample slot to be operated separately, avoiding interference and sample loss during operation, and improving the flexibility of the experiment and the accuracy of sample processing;
[0017] 3. This multi-sample immunohistochemistry test plate simplifies the daily maintenance and cleaning process of the equipment through the drainage system at the bottom and the selection of easy-to-clean materials. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 This is a schematic diagram of the three-dimensional structure of the multi-sample immunohistochemistry detection plate of the utility model;
[0019] Figure 2 This is a schematic diagram of opening the detection board of the utility model;
[0020] Figure 3 This is a schematic diagram of the cross-sectional structure of the locking device of the utility model;
[0021] Figure 4 This is a schematic diagram of the bottom structure of the detection board of the utility model.
[0022] In the figure: 1. Shell; 2. Bottom plate; 3. Detection plate mechanism; 301. Edge sealing; 302. Marking plate; 303. Barcode; 304. Sample slot; 305. Micropore; 306. Cover plate; 307. Handle; 308. Lock; 309. Connecting rod; 310. Movable block; 311. Movable spring; 312. Latch; 313. Socket; 4. Drain groove; 5. Water outlet; 6. Anti-slip gasket. DETAILED DESCRIPTION
[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0024] See also Figure 1-Figure 4The utility model provides a technical solution: a multi-sample immunohistochemical detection plate, which includes a shell 1, a bottom plate 2, a detection plate mechanism 3, a drainage groove 4, a water outlet 5 and an anti-skid gasket 6. The lower end of the shell 1 is provided with the bottom plate 2, the upper end of the shell 1 is provided with the detection plate mechanism 3, the upper end of the bottom plate 2 is provided with a drainage groove 4, the lower end of the bottom plate 2 is provided with a water outlet 5, and the lower end of the bottom plate 2 is provided with an anti-skid gasket 6. The detection plate mechanism 3 includes an edge seal 301, and the upper end of the shell 1 is provided with several edge seals 301. The shell 1 provides structural support and protection for the entire device to ensure that internal components such as the detection plate mechanism 3 The bottom plate 2 provides a stable base to support the entire device and ensure the stability of the device during use. The drainage groove 4 is designed on the bottom plate to collect and guide the waste liquid generated during the use of the device to avoid liquid accumulation inside the device. The water outlet 5 is located at the end of the drainage groove to discharge the collected liquid out of the device to prevent the liquid from corroding or damaging the inside of the device. The anti-slip gasket 6 is arranged under the bottom plate to increase the friction between the device and the placement surface to prevent the device from sliding or shifting during operation. The edge sealing 301 fixes and protects the edge of the detection board to prevent damage and leakage.
[0025] A marking plate 302 is provided at the front end of the edge seal 301, and a barcode 303 is provided on the marking plate 302. A sample slot 304 is provided inside the edge seal 301, and several micropores 305 are provided on the sample slot 304. A cover plate 306 is provided at the upper end of the edge seal 301, and a handle 307 is provided at the upper edge of the cover plate 306. A lock buckle 308 is provided at the lower end of the cover plate 306. The marking plate 302 is convenient for marking sample information to improve work efficiency and accuracy. The barcode 303 is used for quickly scanning and identifying samples and simplifying the sample processing process. The sample slot 304 is used to place experimental samples to ensure that the samples are fixed and stable during the experiment. The micropores 305 allow gas exchange to maintain the balance of the environment in the sample slot and prevent particles and pollutants from entering. The cover plate 306 covers the sample slot to protect the sample from external contamination. The handle 307 is used to operate the cover plate to facilitate opening and closing to adjust or take samples. The lock buckle 308 ensures that the cover plate is safely locked when closed to prevent accidental opening during transportation or use.
[0026] A connecting rod 309 is provided at the lower end of the handle 307, and a movable block 310 is provided at the lower end of the connecting rod 309. A movable spring 311 is provided at the left end of the movable block 310, and a latch 312 is provided at the right end of the movable block 310. A socket 313 is provided on the edge sealing 301 at a position corresponding to the latch 312. The connecting rod 309 connects the handle with the locking mechanism to transmit the user's operating force to control the opening and closing of the cover. The movable block 310 is connected to the handle through the connecting rod, and opens or locks the cover in response to the operating force. The movable spring 311 provides a reset force for the movable block to keep the cover closed in the non-operating state. The latch 312 cooperates with the socket to achieve mechanical locking of the cover to prevent unintentional opening. The socket 313 receives the latch and cooperates with the locking mechanism to fix the cover to maintain the closed state of the equipment and protect the safety of the internal samples.
[0027] Working principle: The working principle of the whole device includes several key parts: the detection plate mechanism 3 installed above the shell 1 is used to place and fix the sample, wherein the edge seal 301 provides additional closed protection around the outside, and a marking plate 302 is installed above each edge seal 301. The barcode 303 on these marking plates is used to quickly identify and record sample data. The micropores 305 in the sample slot 304 are used to accommodate specific samples. These samples are exposed to the detection environment through the sample slot 304. The top of the sample slot is protected by a cover plate 306 to ensure that the sample is not directly disturbed by the outside world. The cover plate 306 can be locked by a lock 308. When locking or releasing on the edge sealing 301 and operating the cover 306, the connecting rod 309 and the movable block 310 are operated by the handle 307, the movable spring 311 supports the elastic movement of the movable block, and the pin 312 cooperates with the socket 313 to realize the locking and unlocking functions of the cover. The bottom plate 2 is located at the lower end of the shell 1, and the drainage groove 4 and the water outlet 5 therein are used to manage and discharge any liquid that may be generated during the detection process to ensure the hygiene and dryness of the device. The anti-skid gasket 6 is located at the lower end of the bottom plate to enhance the stability of the equipment and the anti-skid effect during operation. The design of the overall structure is aimed at achieving safe storage of samples, accurate detection and easy operation.
[0028] Finally, it should be noted that the above content is only used to illustrate the technical solution of the utility model, rather than to limit the protection scope of the utility model. Simple modifications or equivalent substitutions of the technical solution of the utility model by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the utility model.
Claims
1. A multi-sample immunohistochemical detection plate, comprising a housing (1), a bottom plate (2), a detection plate mechanism (3), a drainage groove (4), a water outlet (5) and an anti-slip gasket (6), characterized in that: A bottom plate (2) is provided at the lower end of the shell (1), a detection plate mechanism (3) is provided at the upper end of the shell (1), a drainage groove (4) is provided at the upper end of the bottom plate (2), a water outlet hole (5) is provided at the lower end of the bottom plate (2), an anti-slip gasket (6) is provided at the lower end of the bottom plate (2), the detection plate mechanism (3) comprises an edge seal (301), and a plurality of edge seals (301) are provided at the upper end of the shell (1).
2. A multi-sample immunohistochemistry test plate according to claim 1, characterized in that: A marking plate (302) is provided at the front end of the edge sealing (301), and a barcode (303) is provided on the marking plate (302).
3. A multi-sample immunohistochemistry test plate according to claim 1, characterized in that: A sample groove (304) is provided inside the edge seal (301), and a plurality of micropores (305) are provided on the sample groove (304).
4. The multi-sample immunohistochemistry test plate according to claim 1, characterized in that: A cover plate (306) is provided at the upper end of the edge seal (301), a handle (307) is provided at the upper edge of the cover plate (306), and a lock buckle (308) is provided at the lower end of the cover plate (306).
5. A multi-sample immunohistochemistry test plate according to claim 4, characterized in that: A connecting rod (309) is provided at the lower end of the handle (307), and a movable block (310) is provided at the lower end of the connecting rod (309).
6. A multi-sample immunohistochemistry test plate according to claim 5, characterized in that: A movable spring (311) is provided at the left end of the movable block (310), and a latch (312) is provided at the right end of the movable block (310).
7. The multi-sample immunohistochemistry test plate according to claim 1, characterized in that: An insertion hole (313) is provided on the edge sealing (301) at a position corresponding to the latch pin (312).