Incubation plate device of biological chip and sample analyzer

Abstract

The utility model relates to an incubation disc device of a biological chip and a sample analyser, the incubation disc device of the biological chip comprises a mounting part, a reaction disc, a driving mechanism and a limiting mechanism, the limiting mechanism comprises a limiting piece and a rotating disc, and the rotating disc is in transmission connection with the reaction disc, so that when the driving mechanism drives the reaction disc to rotate, the rotating disc is driven by the driving mechanism to rotate; the reaction disc can drive the rotating disc to rotate, and then the limiting piece is arranged on the mounting part, so that the rotating disc stops rotating when the rotating disc rotates until the abutting piece abuts against the limiting piece, and meanwhile, the reaction disc stops rotating, so that the rotating angle of the reaction disc is limited, and the reaction disc is prevented from continuously rotating in the clockwise direction or the anticlockwise direction; therefore, the wire harness is wound and damaged.

Description

Technical Field

[0001] The present application relates to the technical field of in vitro detection equipment, and in particular to an incubation tray device and a sample analyzer for a biochip. Background Art

[0002] In the fully automatic biochip analyzer, the biochip first needs to react with serum, and then react with the labeled enzyme secondary antibody to form a sandwich product. Then, the luminescent substrate is added to catalyze the luminescence, and the photoelectric signal is collected by the camera. The concentration value of the corresponding indicator is calculated by the intensity of the photoelectric signal. The reaction between the biochip and serum and the reaction between the labeled enzyme secondary antibody require a stable and accurate temperature environment for the biochip to be incubated, so as to meet the analysis requirements.

[0003] In the existing fully automatic biochip analyzer, the temperature is controlled by the metal bath of the incubation tray to achieve stable and accurate temperature control of the biochip. However, the temperature control mechanism on the incubation tray is constrained by the wire harness, so that when the incubation tray continues to rotate in the same direction, the wire harness of the temperature control mechanism will be entangled, resulting in wire breakage. Therefore, at present, when the temperature is controlled by the metal bath of the incubation tray, the incubation tray cannot rotate, so it is impossible to realize the simultaneous operation of multiple stations. Utility Model Content

[0004] Based on this, it is necessary to provide an incubation tray device for a biochip to address the problem that when the incubation tray continuously rotates in the same direction, the wiring harness of the temperature control mechanism becomes entangled and causes wire breakage.

[0005] In a first aspect, an embodiment of the present application provides an incubation tray device for a biochip, the incubation tray device for the biochip comprising:

[0006] Mounting plate;

[0007] A reaction disk, the reaction disk is rotatably connected to the mounting plate, and the reaction disk is used to place a biochip;

[0008] A driving mechanism, the driving mechanism is fixed to the mounting plate, and the driving mechanism can drive the reaction disk to rotate;

[0009] The limiting mechanism comprises a limiting member and a rotating disk, wherein the limiting member is fixed on the mounting plate, the rotating disk is drivingly connected to the reaction disk, the rotating disk can rotate under the drive of the reaction disk, and an abutment member is fixedly provided on the rotating disk, and the abutment member can abut against the limiting member along the rotation direction of the rotating disk to limit the rotation angle of the reaction disk.

[0010] In one embodiment, the limiting mechanism also includes a photoelectric sensor and a light shielding plate, wherein the photoelectric sensor is fixed on the mounting plate, and the light shielding plate is fixed on the rotating disk, and the light shielding plate can block the light signal emitted by the photoelectric sensor, and the photoelectric sensor can monitor the rotating disk rotating back to the initial position.

[0011] In one embodiment, the reaction disk is rotatably connected to the mounting plate via a rotating shaft, a first synchronous wheel is fixedly provided on the rotating shaft, the driving mechanism includes a driving member, a first belt, and a second synchronous wheel, the driving member is fixed on the mounting plate, the second synchronous wheel is fixedly provided on the output end of the driving member, one end of the first belt is sleeved on the first synchronous wheel, and the other end of the first belt is sleeved on the second synchronous wheel.

[0012] In one embodiment, a third synchronous wheel is provided at the bottom of the rotating shaft, the rotating disk is fixed on the fourth synchronous wheel, the rotating disk and the fourth synchronous wheel are arranged along the same center axis, one end of the second belt is sleeved on the third synchronous wheel, and the other end of the second belt is sleeved on the fourth synchronous wheel.

[0013] In one embodiment, the reduction ratio of the third synchronous wheel and the fourth synchronous wheel is set to 3:4.

[0014] In one of the embodiments, a mounting sleeve is fixedly disposed on the mounting plate, a first bearing is disposed in the mounting sleeve, and the rotating shaft is rotatably connected to the mounting sleeve via the first bearing.

[0015] In one embodiment, the limiting mechanism further includes a wheel axle and a second bearing, the wheel axle is fixed to the mounting plate, and the wheel axle is rotatably connected to the rotating disk via the second bearing.

[0016] In one embodiment, the incubation tray device of the biochip further includes a temperature control mechanism, which includes a heating film and a thermal insulation layer, wherein the heating film is disposed at the bottom of the reaction tray, and the thermal insulation layer is disposed at the outer side of the reaction tray.

[0017] In one embodiment, the temperature control mechanism also includes a temperature sensor and an over-temperature protector. The temperature sensor is arranged in the reaction disk and is used to monitor the temperature in the reaction disk. The temperature sensor and the heating film are respectively electrically connected to the over-temperature protector. The over-temperature protector can control the switch of the heating film according to the temperature in the reaction disk monitored by the temperature sensor.

[0018] In a second aspect, an embodiment of the present application further provides a sample analyzer, comprising the above-mentioned incubation tray device of the biochip.

[0019] Beneficial effects:

[0020] The above-mentioned incubation disk device and sample analyzer for the biochip, the incubation disk device for the biochip includes a mounting portion, a reaction disk, a driving mechanism and a limiting mechanism, the limiting mechanism includes a limiting piece and a rotating disk, and the rotating disk is connected to the reaction disk through a transmission connection, so that when the driving mechanism drives the reaction disk to rotate, the reaction disk can drive the rotating disk to rotate, and then by arranging a limiting piece on the mounting portion, when the rotating disk rotates to the abutment piece and the limiting piece abuts, the rotating disk stops rotating, and the reaction disk stops rotating at the same time, thereby limiting the rotation angle of the reaction disk, and then preventing the reaction disk from continuously rotating in the clockwise direction or counterclockwise direction, causing the wiring harness to be entangled and the wiring harness to be damaged. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 A schematic diagram of the structure of an incubation tray device for a biochip provided in some embodiments of the present application.

[0022] Figure 2 for Figure 1 A top view of the incubation tray device of the biochip is shown.

[0023] Figure 3 for Figure 1 A side cross-sectional view of the incubation tray device of the biochip is shown.

[0024] Figure 4 for Figure 1 A schematic diagram of the partial structure of the incubation tray device of the biochip is shown.

[0025] Figure 5 for Figure 1 The schematic diagram of the structure of the limiting mechanism of the incubation tray device of the biochip is shown.

[0026] Reference numerals:

[0027] 1. Mounting plate; 11. Mounting sleeve; 12. First bearing;

[0028] 2. Reaction disk; 21. Rotating shaft; 22. First synchronous wheel; 23. Third synchronous wheel; 24. Second belt;

[0029] 3. Driving mechanism; 31. Driving member; 32. Second synchronous wheel; 33. First belt;

[0030] 4. Temperature control mechanism; 41. Heating film; 42. Insulation layer; 43. Temperature sensor; 44. Over-temperature protector; 45. Heat insulation board; 46. Bottom plate;

[0031] 5. Limiting mechanism; 51. Rotating plate; 511. Abutting member; 52. Limiting member; 53. Photoelectric sensor; 54. Light shield; 55. Fourth synchronous wheel; 56. Wheel shaft; 57. Second bearing; 58. First fixed seat; 59. Limiting ring;

[0032] 100. Biochip;

[0033] 200. Reaction cup. DETAILED DESCRIPTION

[0034] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific embodiments disclosed below.

[0035] In the description of the present application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application.

[0036] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of this application, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0037] In this application, unless otherwise clearly specified and limited, if the terms "installed", "connected", "connected", "fixed" and the like appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances.

[0038] In the present application, unless otherwise clearly specified and limited, if there is a description that a first feature is "above" or "below" a second feature, etc., or similar descriptions appear, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0039] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only implementation method.

[0040] First, see Figure 1-Figure 3 An incubation tray device for a biochip provided in one embodiment of the present application comprises a mounting plate 1, a reaction tray 2, a driving mechanism 3 and a limiting mechanism 5; the reaction tray 2 is rotatably connected to the mounting plate 1, and the reaction tray 2 is used to place the biochip 100; the driving mechanism 3 is fixed on the mounting plate 1, and the driving mechanism 3 can drive the reaction tray 2 to rotate.

[0041] Refer to Figure 4 and Figure 5 The limiting mechanism 5 includes a limiting member 52 and a rotating disk 51. The limiting member 52 is fixed on the mounting plate 1. The rotating disk 51 is transmission-connected with the reaction disk 2. The rotating disk 51 can rotate driven by the reaction disk 2. An abutment member 511 is fixedly provided on the rotating disk 51. The abutment member 511 can abut against the limiting member 52 along the rotation direction of the rotating disk 51 to limit the rotation angle of the reaction disk 2.

[0042] An incubation disk device for a biochip provided in an embodiment of the present application is connected to a reaction disk 2 through a rotating disk 51, so that when a driving mechanism 3 drives the reaction disk 2 to rotate, the reaction disk 2 can drive the rotating disk 51 to rotate, and then a limiting member 52 is provided on the mounting plate 1, so that when the rotating disk 51 rotates to the point where the abutting member 511 abuts against the limiting member 52, the rotating disk 51 stops rotating, and the reaction disk 2 stops rotating at the same time, thereby limiting the rotation angle of the reaction disk 2, thereby preventing the reaction disk 2 from continuously rotating in a clockwise or counterclockwise direction, causing the wiring harness to be entangled and damaged.

[0043] like Figure 3-Figure 5 As shown, in some embodiments, the limiting mechanism 5 in the embodiment of the present application also includes a photoelectric sensor 53 and a light blocking piece 54. The photoelectric sensor 53 is fixed on the mounting plate 1, and the light blocking piece 54 is fixed on the rotating disk 51. The light blocking piece 54 can rotate under the drive of the rotating disk 51. The light blocking piece 54 can block the light signal emitted by the photoelectric sensor 53, and the photoelectric sensor 53 can monitor the rotating disk 51 to rotate back to the initial position.

[0044] The light shielding sheet 54 in the embodiment of the present application is fixedly arranged on the rotating disk 51 and extends from the center of the rotating disk 51 to the outer side, and is at least partially located outside the rotating disk 51. The light shielding sheet 54 can rotate along with the rotation of the rotating disk 51. The photoelectric sensor 53 in the embodiment of the present application is fixed on the mounting plate 1. The photoelectric sensor 53 includes a photoelectric signal detection area. When the light shielding sheet 54 rotates along with the rotating disk 51, the light shielding sheet 54 can pass through the photoelectric signal detection area to block the photoelectric signal. When the rotating disk 51 is in the initial position, the light shielding sheet 54 is located in the photoelectric signal detection area of ​​the photoelectric sensor 53. Then, the rotating disk 51 rotates along the first rotation direction until the abutment member 511 abuts against the limit member 52, and the rotating disk 51 and the reaction disk 2 stop rotating. Then, they rotate in the second rotation direction opposite to the first rotation direction until the light shielding sheet 54 returns to the photoelectric signal detection area of ​​the photoelectric sensor 53. At this time, the photoelectric sensor 53 obtains a zeroing signal, and then the rotating disk 51 rotates along the first rotation direction again, and this cycle is repeated.

[0045] Of course, in other embodiments, two photoelectric sensors 53 may be provided, one located at the initial position of the light blocking sheet 54, and the other located at the abutment position between the abutment member 511 and the limiting member 52, and the photoelectric sensor 53 is electrically connected to the driving mechanism 3 to control the driving mechanism 3 to drive the reaction disk 2 to rotate along the first rotation direction or the second rotation direction.

[0046] In addition, in order to save production costs, the abutment 511 in the embodiment of the present application is a limiting screw. On the one hand, the limiting screw can fix the light blocking sheet 54 on the rotating disk 51, and on the other hand, the blocking member can rotate along with the rotating disk 51 until it rotates to abut against the limiting member 52, so that the rotating disk 51 and the reaction disk 2 connected to the rotating disk 51 stop rotating, thereby limiting the rotation angle of the reaction disk 2, thereby preventing the reaction disk 2 from rotating in the same rotation direction and causing damage to the wiring harness.

[0047] like Figure 3 and Figure 4 As shown, in some embodiments, the reaction disk 2 in the embodiment of the present application is rotatably connected to the mounting plate 1 through a rotating shaft 21, a first synchronous wheel 22 is fixedly provided on the rotating shaft 21, the driving mechanism 3 includes a driving member 31, a first belt 33, and a second synchronous wheel 32, the driving member 31 is fixed on the mounting plate 1, a second synchronous wheel 32 is fixedly provided on the output end of the driving member 31, one end of the first belt 33 is sleeved on the first synchronous wheel 22, and the other end of the first belt 33 is sleeved on the second synchronous wheel 32.

[0048] In the embodiment of the present application, the second synchronous wheel 32 is driven to rotate by the driving member 31, and the first synchronous wheel 22 is rotated together by the first belt 33, so as to realize the rotation of the rotating shaft 21, and then the reaction disk 2 fixed on the rotating shaft 21 is rotated. Of course, in other embodiments, the first belt 33 can be replaced by a chain, and the first synchronous wheel 22 and the second synchronous wheel 32 can be replaced by gears, and the specific method of realizing the transmission connection is not limited here.

[0049] like Figure 3 and Figure 4 As shown, in some embodiments, in the embodiment of the present application, a third synchronous wheel 23 is provided at the bottom of the rotating shaft 21, the rotating disk 51 is fixed on the fourth synchronous wheel 55, the rotating disk 51 and the fourth synchronous wheel 55 are arranged along the same center axis, one end of the second belt 24 is sleeved on the third synchronous wheel 23, and the other end of the second belt 24 is sleeved on the fourth synchronous wheel 55.

[0050] In the embodiment of the present application, the second synchronous wheel 32 is driven to rotate by the driving member 31, and the first synchronous wheel 22 is rotated together by the first belt 33, so as to realize the rotation of the rotating shaft 21, and the third synchronous wheel 23 is fixed on the rotating shaft 21. The rotating shaft 21 drives the third synchronous wheel 23, and then the third synchronous wheel 23 and the fourth synchronous wheel 55 are connected by the second belt 24, so that the fourth synchronous wheel 55 rotates together with the third synchronous wheel 23, so that the rotating disk 51 fixed on the fourth synchronous wheel 55 rotates, until the rotating disk 51 rotates to the point where the abutting member 511 on the rotating disk 51 abuts against the limiting member 52, the rotating disk 51 and the reaction disk 2 cannot continue to rotate in the rotation direction, thereby limiting the rotation angle of the reaction disk 2, thereby preventing the reaction disk 2 from rotating in the same rotation direction, causing damage to the wiring harness.

[0051] Of course, in other embodiments, the second belt 24 may be replaced by a chain, and the third synchronous wheel 23 and the fourth synchronous wheel 55 may be replaced by gears. The specific method of realizing the transmission connection is not limited here.

[0052] like Figure 3 and Figure 4 As shown, in some embodiments, the reduction ratio of the third synchronous wheel 23 and the fourth synchronous wheel 55 in the embodiment of the present application is set to 3:4.

[0053] By setting the reduction ratio of the third synchronous wheel 23 and the fourth synchronous wheel 55 to 3:4, when the fourth synchronous wheel 55 rotates 360°, the third synchronous wheel 23 can rotate 480°. Due to the presence of the abutment 511 and the limiter 52, when the fourth synchronous wheel 55 rotates clockwise or counterclockwise, the limiter 52 and the abutment 511 will abut, and at this time, the fourth synchronous wheel 55 and the third synchronous wheel 23 will stop rotating, so that the reaction disk 2 will not rotate indefinitely only in the clockwise direction or only in the counterclockwise direction, thereby avoiding the problem of the wiring harness of the temperature control component being entangled.

[0054] In addition, in the embodiment of the present application, due to the presence of the limit member 52 and the abutment member 511, the actual rotation angle of the fourth synchronous wheel 55 will be less than 360°, but by setting the reduction ratio of the third synchronous wheel 23 and the fourth synchronous wheel 55 to 3:4, the rotation angle of the third synchronous wheel 23 can be greater than 360° and less than 480°, so that the reaction disk 2 cannot rotate continuously in the clockwise direction or counterclockwise direction, while ensuring that the rotation angle of the reaction disk 2 can be greater than 360°, so that the biochip 100 on the reaction disk 2 is fully heated, thereby improving the incubation effect.

[0055] like Figure 1 and Figure 3As shown, in some embodiments, a mounting sleeve 11 is fixedly disposed on the mounting plate 1 in the embodiment of the present application, a first bearing 12 is disposed in the mounting sleeve 11 , and the rotating shaft 21 is inserted in the first bearing 12 .

[0056] By fixing the mounting sleeve 11 on the mounting plate 1 and arranging the first bearing 12 in the mounting sleeve 11, the friction between the rotating shaft 21 and the mounting portion can be greatly reduced, thereby making the rotation smoother and more stable, thereby greatly extending the service life of the rotating shaft 21. In addition, it can also greatly reduce the energy consumption caused by friction and reduce production costs.

[0057] like Figure 3 As shown, in some embodiments, the limiting mechanism 5 in the embodiment of the present application further includes a wheel shaft 56 and a first bearing 12, the wheel shaft 56 is fixed on the mounting plate 1, the wheel shaft 56 is inserted in the first bearing 12, and the rotating disk 51 is sleeved outside the first bearing 12. By fixing the mounting sleeve 11 on the mounting plate 1 and arranging the first bearing 12 in the mounting sleeve 11, the friction between the rotating shaft 21 and the mounting portion can be greatly reduced, so that the rotation is smoother and more stable, thereby greatly extending the service life of the rotating shaft 21. In addition, it can also greatly reduce the energy consumption caused by friction and reduce production costs.

[0058] In some embodiments, the axle 56 in the embodiment of the present application is fixed to the mounting plate 1 through a first fixing seat 58 , and a limiting ring 59 is provided at one end of the axle 56 away from the first fixing seat 58 .

[0059] By setting a limiting ring 59 and a first fixing seat 58 to fix the axle 56 on the mounting plate 1, the axial position of the axle 56 can be limited, so that the axle 56 can be stably fixed on the mounting plate 1, thereby preventing the axle 56 from loosening, causing the limiting mechanism 5 to fail, and causing the reaction disk 2 to continue to rotate in the same direction of rotation, causing damage to the wiring harness, thereby affecting the incubation effect of the incubation disk device of the biochip.

[0060] like Figure 1-Figure 3 As shown, in some embodiments, the incubation tray device of the biochip in the embodiment of the present application also includes a temperature control mechanism 4, the temperature control mechanism 4 includes a heating film 41 and a thermal insulation layer 42, the heating film 41 is arranged at the bottom of the reaction tray 2, and the thermal insulation layer 42 is arranged on the outside of the reaction tray 2.

[0061] The biochip 100 is heated by the heating film 41 . In addition, the heat loss can be greatly reduced by providing the heat preservation layer 42 , thereby saving energy loss.

[0062] In the embodiment of the present application, the incubation tray device is heated by a metal bath, which can more stably and accurately control the incubation temperature of the incubation tray device, and will not be affected by the ambient temperature and cause the incubation temperature to fluctuate and be difficult to control.

[0063] Metal bath heating is a process of heating hot water or other liquids to a constant temperature and then placing the sample to be tested in it for constant temperature treatment. Metal bath heating has the characteristics of fast heat absorption and uniform heat transfer, and has good stability and can provide a stable temperature environment.

[0064] Of course, in other embodiments, other heating methods may be used, such as a thermal radiation heater, and the radiation energy of the radiation heater may be adjusted according to factors such as the power and radiation distance of the heater, so as to achieve heating of the chip.

[0065] like Figure 1-Figure 3 As shown, in some embodiments, the temperature control mechanism 4 in the embodiment of the present application also includes a temperature sensor 43 and an over-temperature protector 44. The temperature sensor 43 is arranged in the reaction disk 2 and is used to monitor the temperature in the reaction disk 2. The over-temperature protector 44 is electrically connected to the temperature sensor 43 and the heating film 41. The over-temperature protector 44 can control the switch of the heating film 41 according to the temperature in the reaction disk 2 monitored by the temperature sensor 43.

[0066] By setting up the temperature sensor 43, the temperature inside the reaction disk 2 can be monitored in real time, which is convenient for the staff to understand the temperature inside the reaction disk 2 and adjust the temperature. In addition, by setting an over-temperature protector 44 electrically connected to the temperature sensor 43 and the heating film 41 in the reaction disk 2, the over-temperature protector 44 can control the heating film 41 according to the temperature inside the reaction disk 2 monitored by the temperature sensor 43. When the temperature inside the reaction disk 2 exceeds the maximum temperature preset by the over-temperature protector 44, the over-temperature protector 44 will disconnect the circuit, so that the heating film 41 stops heating the reaction disk 2, so as to ensure that the incubation temperature is maintained within a reasonable range.

[0067] In addition, in some embodiments, the temperature control mechanism 4 may also include a low-temperature protector, which is also electrically connected to the temperature sensor 43 and the heating film 41. The low-temperature protector can control the heating film 41 according to the temperature in the reaction disk 2 monitored by the temperature sensor 43. When the temperature in the reaction disk 2 is lower than the minimum temperature preset by the low-temperature protector, the low-temperature protector will reconnect the circuit so that the heating film 41 will start heating the reaction disk 2 again to ensure that the incubation temperature is maintained within a reasonable range.

[0068] In some embodiments, the temperature control mechanism 4 further includes a heat insulation plate 45 and a bottom plate 46 . The heat insulation plate 45 is disposed at the bottom of the reaction disk 2 , and the bottom plate 46 is disposed inside the reaction disk 2 .

[0069] By arranging the heat insulation plate 45 at the bottom of the reaction disk 2 , the heat in the reaction disk 2 will not be conducted to the rotating shaft 21 and the driving mechanism 3 , thereby preventing the high temperature from affecting the rotating shaft 21 and the driving mechanism 3 .

[0070] In some embodiments, a plurality of reaction cups 200 for placing biochips 100 are arranged in the reaction disk 2, and the reaction disk 2 is divided into a serum reaction area and a secondary antibody reaction area, wherein the inner circle 48 stations are the serum reaction area, and the outer circle 32 stations are the secondary antibody reaction area.

[0071] In a second aspect, an embodiment of the present application further provides a sample analyzer, comprising the above-mentioned incubation tray device of the biochip.

[0072] In some embodiments, the sample analyzer further includes a robotic arm, which can take and place the biochip 100 in the incubation tray device of the biochip, thereby greatly speeding up the working efficiency of the sample analyzer and greatly improving the degree of automation.

[0073] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0074] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be construed as limiting the scope of the patent application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent application shall be subject to the attached claims.

Claims

1. An incubation tray device for a biochip, characterized in that: The incubation tray device of the biochip comprises: Mounting plate; A reaction disk, the reaction disk is rotatably connected to the mounting plate, and the reaction disk is used to place a biochip; A driving mechanism, the driving mechanism is fixed to the mounting plate, and the driving mechanism can drive the reaction disk to rotate; The limiting mechanism comprises a limiting member and a rotating disk, wherein the limiting member is fixed on the mounting plate, the rotating disk is drivingly connected to the reaction disk, the rotating disk can rotate under the drive of the reaction disk, and an abutment member is fixedly provided on the rotating disk, and the abutment member can abut against the limiting member along the rotation direction of the rotating disk to limit the rotation angle of the reaction disk.

2. The incubation tray device for a biochip according to claim 1, characterized in that: The limiting mechanism also includes a photoelectric sensor and a light shielding plate. The photoelectric sensor is fixed on the mounting plate, and the light shielding plate is fixed on the rotating disk. The light shielding plate can block the light signal emitted by the photoelectric sensor, and the photoelectric sensor can monitor the rotating disk rotating back to the initial position.

3. The incubation tray device for a biochip according to claim 1, characterized in that: The reaction disk is rotatably connected to the mounting plate via a rotating shaft, a first synchronous wheel is fixedly disposed on the rotating shaft, the driving mechanism comprises a driving member, a second synchronous wheel, and a first belt, the driving member is fixed to the mounting plate, the second synchronous wheel is fixedly disposed on the output end of the driving member, one end of the first belt is sleeved on the first synchronous wheel, and the other end of the first belt is sleeved on the second synchronous wheel.

4. The incubation tray device for a biochip according to claim 3, characterized in that: A third synchronous wheel is arranged at the bottom of the rotating shaft, the rotating disk is fixed on the fourth synchronous wheel, the rotating disk and the fourth synchronous wheel are arranged along the same central axis, one end of the second belt is sleeved on the third synchronous wheel, and the other end of the second belt is sleeved on the fourth synchronous wheel.

5. The incubation tray device for a biochip according to claim 4, characterized in that: The reduction ratio of the third synchronous wheel and the fourth synchronous wheel is set to 3:

4.

6. The incubation tray device for a biochip according to claim 3, characterized in that: The mounting plate is also fixedly provided with a mounting sleeve, a first bearing is provided in the mounting sleeve, and the rotating shaft is rotatably connected to the mounting sleeve via the first bearing.

7. The incubation tray device for a biochip according to claim 1, characterized in that: The limiting mechanism further includes a wheel axle and a second bearing, wherein the wheel axle is fixed to the mounting plate, and the wheel axle is rotatably connected to the rotating disk via the second bearing.

8. The incubation tray device for a biochip according to claim 1, characterized in that: The incubation tray device of the biochip further comprises a temperature control mechanism, which comprises a heating film and a heat preservation layer, wherein the heating film is arranged at the bottom of the reaction tray, and the heat preservation layer is arranged at the outer side of the reaction tray.

9. The incubation tray device for a biochip according to claim 8, characterized in that: The temperature control mechanism also includes a temperature sensor and an over-temperature protector. The temperature sensor is arranged in the reaction disk and is used to monitor the temperature in the reaction disk. The temperature sensor and the heating film are electrically connected to the over-temperature protector respectively. The over-temperature protector can control the switch of the heating film according to the temperature in the reaction disk monitored by the temperature sensor.

10. A sample analyzer, characterized in that: An incubation tray device comprising a biochip as described in any one of claims 1-9.

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