Experimental device for harm-avoiding cooperative behavior

By designing an experimental device including a water tank, a round table and a spring, the mice are utilizing the nature of water fear and the different stiffness coefficients of the spring, the existing device is complex and harmful to the mice, and the effect of quickly learning cooperative behavior and shortening training time is achieved.

CN222840278UActive Publication Date: 2025-05-09FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202421080612.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-17
Publication Date
2025-05-09
Estimated Expiration
2034-05-17

AI Technical Summary

Technical Problem

The existing experimental devices for avoiding harm behavior are too complex, exceeding the learning ability of mice, causing harm to mice, and training time is too long.

Method used

An experimental device including a water tank, a round table and a spring was designed to use the mice's nature of fearing water and the different stiffness coefficients of the spring to gradually increase the mice's cooperation awareness and shorten the training time.

Benefits of technology

Through this device, mice can learn cooperative behavior faster, reduce harm to mice, shorten training time, and improve experimental efficiency.

✦ Generated by Eureka AI based on patent content.

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    Figure CN222840278U_ABST
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Abstract

The utility model discloses an experimental device for a harm-avoiding cooperation behavior, which comprises a water tank, and a heating device is arranged in the water tank. The circular truncated cone is placed in the water tank, a transparent column is installed at the center of the top of the circular truncated cone, a spring is connected to the center of the bottom of the circular truncated cone, and the bottom of the spring is fixed to a support. In the experiment process, the circular truncated cone is placed in the water tank, water is added into the water tank till the water level is 1-2 cm away from the circular truncated cone, the water is heated through the heating device, then the two mice are placed in the water, and the time when the mice reach balance on the circular truncated cone is recorded. Through the device, mice can learn cooperation, the experiment time is shortened, and damage to the mice is relieved.
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Description

Technical Field

[0001] The utility model relates to the field of medical research, in particular to an experimental device for harm-avoiding cooperative behavior. Background Art

[0002] Cooperation is a widespread social behavior that is essential for the survival of many species, including humans. The study of cooperative behavior in mice can help promote the study of a variety of diseases, such as autism and Alzheimer's disease. Although mice show limited cooperative abilities in certain behavioral paradigms, exploring their cooperative behavior and its underlying neural mechanisms remains an interesting question.

[0003] According to the motivation of mice's cooperative behavior, it can be divided into two categories: profit-seeking cooperative behavior and harm-avoiding cooperative behavior. At present, most experimental devices use the profit-seeking motivation of mice, usually by fasting or water deprivation, so as to stimulate the motivation of mice to seek profit. In addition, the existing experimental devices have a long initial learning time, because mice can only get rewards when they touch buttons or levers in accidental activities. The experimental devices for harm-avoiding cooperative behavior currently used are too complicated, which exceeds the learning ability of mice and causes great harm to mice, and the training time required is too long. For example, two mice must press the button at the same time to avoid electric shock. This device obviously exceeds the learning ability of mice and will cause harm to mice, and even the mice will become numb. Utility Model Content

[0004] The utility model provides an experimental device for harm-avoiding cooperative behavior, aiming to solve the above-mentioned problems existing in the background technology. The device can ensure that mice learn to cooperate, shorten the experimental time, and reduce the harm to the mice.

[0005] The technical solutions provided by this utility model are as follows:

[0006] An experimental device for harm avoidance cooperative behavior, comprising a water tank, wherein a heating device is provided in the water tank;

[0007] A truncated table, the truncated table is placed in the water tank, a transparent column is installed at the center of the top of the truncated table, a spring is connected at the center of the bottom of the truncated table, and the bottom of the spring is fixed on the bracket;

[0008] During the experiment, the truncated table was placed in the water tank, water was added to the water tank until the water level was 1-2 cm away from the truncated table, the water was heated by a heating device, and then two mice were placed in the water, and the time it took for the mice to reach equilibrium on the truncated table was recorded.

[0009] Furthermore, it also includes a stirring device, which is used to stir during the heating process so that the water in the water tank is heated evenly.

[0010] Furthermore, the heating device includes a heating component, a first partition and a second partition are provided in the water tank, and the heating component is provided between the first partition and the second partition.

[0011] Further, the stirring device is a magnetic stirrer, and the magnetic stirrer is arranged in the space between the second partition and the bottom of the water tank;

[0012] A magnetic stirrer is placed in the water tank.

[0013] Furthermore, a thermometer is provided on the side wall of the water tank, and the thermometer is used to measure the temperature of water.

[0014] Furthermore, the heating component is a heating wire or a heating copper tube.

[0015] Furthermore, the truncated table is connected to the spring via an adhesive hook.

[0016] Furthermore, a water outlet is provided at the bottom of the side wall of the water tank.

[0017] Furthermore, the bracket is a regular hexagonal bracket.

[0018] Compared with the prior art, the beneficial effects of the utility model are:

[0019] 1. Taking advantage of the fact that mice are afraid of water but good at swimming, the harm caused by existing experimental techniques to mice can be reduced;

[0020] 2. Using springs with different stiffness coefficients, the balance range can be adjusted to gradually increase the cooperative awareness of mice;

[0021] 3. Using the fear of water in mice can shorten the time of initial training;

[0022] 4. Using a thermometer or a constant temperature water tank can prevent the mice from being harmed by low water temperature. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a schematic diagram of the structure of a water tank in an experimental device for harm-avoidance cooperative behavior in an embodiment of the utility model;

[0024] Figure 2 It is a schematic diagram of the overall structure of the round table in the experimental device for harm-avoidance cooperative behavior in an embodiment of the utility model.

[0025] The reference numerals are as follows:

[0026] 1-water tank, 2-first baffle, 3-magnetic stirring bar, 4-second baffle, 5-heating component, 6-magnetic stirrer, 7-thermometer, 8-round table, 9-transparent column, 10-spring, 11-bracket, 12-drainage outlet, 13-sticky hook. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical scheme and advantages of the embodiments of the present application clearer, the technical scheme in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the embodiments described below are part of the embodiments of the present application, rather than all of the embodiments. The components of the embodiments of the present application described and shown in the drawings here can be arranged and designed in various different configurations.

[0028] Therefore, the detailed description of the embodiments of the present application provided below in conjunction with the accompanying drawings is intended to represent only selected embodiments of the present application, and is not intended to limit the scope of protection claimed in the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present application.

[0029] It should be understood that in the description of the embodiments of the present utility model, the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate the orientation or position relationship based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the embodiments of the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the embodiments of the present utility model. In addition, the terms "first" and "second" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the embodiments of the present utility model, the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined.

[0030] In the description of the embodiments of the present utility model, it should be noted that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or can communicate with each other; it can be directly connected, or indirectly connected through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the embodiments of the present utility model can be understood according to specific circumstances.

[0031] See also Figure 1 , Figure 2 The utility model provides an experimental device for avoiding harm cooperative behavior, comprising a water tank 1, in which a heating device is arranged.

[0032] The round table 8 is placed in the water tank 1, a transparent column 9 is installed at the center of the top of the round table 8, a spring 10 is connected to the center of the bottom of the round table 8, and the bottom of the spring 10 is fixed to the bracket 11. The transparent column 9 is used to prevent the two mice from running directly to the center of the round table 8 without cooperative behavior. In this embodiment, a sticky hook 13 is installed at the center of the bottom of the round table 8, and the sticky hook 13 is connected to the spring 10. The sticky hook 13 is used to fix the spring 10 but is convenient for disassembling and replacing the spring 10.

[0033] In this embodiment, the water tank 1 is a glass product, and the length, width and height are 60cm, 50cm and 40cm respectively. In order to ensure that the round table 8 can be placed normally in the water tank 1, the round table 8 can be made of light material, so that it can be supported by the spring 10. The design idea of ​​the device is: put two mice in the water of the water tank 1, place them diagonally, and gradually heat the water. The mice will climb onto the round table 8 driven by the instinct of seeking benefits and avoiding harm. The round table 8 is supported by the spring 10 and the sticky hook 13. Only when the two mice reach balance on the round table 8 can the round table 8 be guaranteed not to tilt. If the two mice do not reach balance on the round table 8, it will cause the round table 8 to tilt and cause the mice to fall into the water. The mice will find the balance point after several attempts and record the time. Then gradually reduce the stiffness coefficient of the spring 10 and repeat the above steps to gradually increase the cooperation consciousness of the mice.

[0034] During the experiment, the truncated table 8 was placed in the water tank 1, water was added to the water tank 1 until the water level was 1-2 cm from the bottom of the truncated table 8, the water was heated by a heating device, and then two mice were put into the water, and the time it took for the mice to reach balance on the truncated table 8 was recorded. The experiment was repeated again by gradually replacing the spring 10 with a reduced stiffness coefficient to increase the cooperation awareness of the mice.

[0035] Optionally, a stirring device is also included, and the stirring device is used to stir during the heating process so that the water in the water tank 1 is heated evenly.

[0036] Optionally, the heating device includes a heating component 5 , a first partition 2 and a second partition 4 are provided in the water tank 1 , and the heating component 5 is provided between the first partition 2 and the second partition 4 .

[0037] Optionally, the stirring device is a magnetic stirrer 6 , which is disposed in the space between the second partition plate 4 and the bottom of the water tank 1 .

[0038] A magnetic stirring bar 3 is placed in the water tank 1 .

[0039] In this embodiment, the stirring device is a magnetic stirrer 6, and the working principle of the magnetic stirrer 6 is not further described. The stirring rate of the magnetic stirrer 3 can be adjusted by adjusting the button on its surface.

[0040] Optionally, a thermometer 7 is provided on the side wall of the water tank 1, and the thermometer 7 is used to measure the temperature of the water. In this embodiment, in order to avoid the water temperature being too high and causing harm to the mice, the water temperature can be adjusted by observing the scale of the thermometer 7. In other embodiments, a constant temperature water tank can also be used, and a non-constant temperature water tank or a constant temperature water tank can be used. The water temperature in the water tank 1 is preferably controlled at 23-25°C.

[0041] Optionally, the heating component 5 is a heating wire or a heating copper tube.

[0042] In this embodiment, the heating component 5 is preferably a heating wire or a heating copper tube, and other heating components may also be selected, which are not listed here one by one.

[0043] Optionally, a water outlet 12 is provided at the bottom of the side wall of the water tank 1. After each experiment, the water in the water tank 1 needs to be drained to prevent the residual odor from adversely affecting the next set of experiments. The water outlet 12 can be plugged with a cork (not shown in the figure) or opened or closed by a water valve.

[0044] Optionally, the bracket 11 is a regular hexagonal bracket.

[0045] The utility model provides an experimental device for harm-avoidance cooperative behavior. The purpose of the device is to provide an experimental device for harm-avoidance cooperative behavior, which can ensure that mice learn and perform cooperative behavior, greatly shorten the training time, and improve the experimental efficiency.

[0046] Compared with the prior art, the device has the following technical effects:

[0047] 1. By taking advantage of the fact that mice are afraid of water but good at swimming, the harm caused to mice by existing experimental techniques can be reduced.

[0048] 2. Using springs with different stiffness coefficients, the balance range can be adjusted to gradually increase the mice's sense of cooperation.

[0049] 3. By taking advantage of the mice's fear of water, the time of initial training can be shortened.

[0050] 4. Using a thermometer or a constant temperature water tank can prevent the mice from being harmed by low water temperature.

[0051] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited thereto. Any changes or substitutions within the technical scope disclosed in the present application should be included in the protection scope of the present application. Therefore, the protection scope of the present application should be based on the protection scope of the claims.

Claims

1. An experimental device for harm avoidance cooperative behavior, characterized in that: It comprises a water tank, in which a heating device is arranged; A truncated table, the truncated table is placed in the water tank, a transparent column is installed at the center of the top of the truncated table, a spring is connected at the center of the bottom of the truncated table, and the bottom of the spring is fixed on the bracket; The water tank is filled with water, the water level is 1-2 cm away from the truncated table, and the heating device is used to heat the water.

2. The experimental device for avoiding harm cooperative behavior according to claim 1, characterized in that: It also includes a stirring device, which is used for stirring during the heating process so that the water in the water tank is heated evenly.

3. The experimental device for avoiding harm cooperative behavior according to claim 2, characterized in that: The heating device comprises a heating assembly. A first partition and a second partition are arranged in the water tank. The heating assembly is arranged between the first partition and the second partition.

4. The experimental device for avoiding harm cooperative behavior according to claim 3, characterized in that: The stirring device is a magnetic stirrer, and the magnetic stirrer is arranged in the space between the second partition and the bottom of the water tank; A magnetic stirrer is placed in the water tank.

5. The experimental device for avoiding harm cooperative behavior according to any one of claims 1 to 4, characterized in that: A thermometer is arranged on the side wall of the water tank, and the thermometer is used to measure the temperature of water.

6. The experimental device for avoiding harm cooperative behavior according to claim 3, characterized in that: The heating component is a heating wire or a heating copper tube.

7. The experimental device for avoiding harm cooperative behavior according to claim 5, characterized in that: The round table is connected to the spring via an adhesive hook.

8. The experimental device for avoiding harm cooperative behavior according to claim 6 or 7, characterized in that: A water outlet is arranged at the bottom of the side wall of the water tank.

9. The experimental device for avoiding harm cooperative behavior according to claim 8, characterized in that: The bracket is a regular hexagonal bracket.