Platelet-rich plasma preparation device

Abstract

The utility model discloses a platelet-rich plasma preparation device, which belongs to the technical field of medical instruments and comprises a main body, the main body is provided with a first chamber, a second chamber and a connecting channel communicated with the first chamber and the second chamber, an upper end cover is mounted at one end, close to the first chamber, of the main body, and a lower end cover is mounted at the other end of the main body. A lower end cover is installed at the end close to the second cavity, the lower end cover is spirally connected with the main body, a screw assembly is installed on the lower end cover and comprises a separation body and a push rod assembly, the separation body is fixedly connected with the push rod assembly, and the push rod assembly is arranged on the screw assembly in a vertically movable mode; the push rod assembly moves up and down to drive the partition body to control opening or closing of the connecting channel. The method is convenient to operate, high in preparation efficiency, flexible and stable in preparation process and small in erythrocyte mixing amount.

Description

Technical Field

[0001] The utility model relates to a platelet-rich plasma preparation device, belonging to the technical field of medical equipment. Background Art

[0002] Platelet-rich plasma (PRP), as an autologous biological therapeutic material, has shown good clinical effects in promoting tissue healing and regeneration, and is therefore widely used in medical cosmetology, orthopedics, dentistry and other fields. PRP extracts high concentrations of platelets from the patient's whole blood. Platelets not only play a key role in the coagulation process, but also release a variety of growth factors, such as PDGF, TGF-β and EGF, which promote cell proliferation and tissue repair. Therefore, increasing the concentration of platelets in PRP is the key to achieving its therapeutic effect.

[0003] The preparation of PRP usually relies on centrifugal separation technology, which separates the components in the blood through centrifugal operations at different speeds and times. The existing PRP preparation devices still have shortcomings in preparation efficiency, operability and platelet enrichment. In addition, there may be significant differences in blood components between different patients, such as platelet count, red blood cell ratio, etc. This requires that the PRP preparation process can be stably and flexibly adjusted to adapt to individual differences. Moreover, the preparation of PRP requires the mixing of red blood cells to be as little as possible. Therefore, a new type of PRP preparation device is urgently needed to improve the purity and preparation efficiency of platelets. Utility Model Content

[0004] The technical problem to be solved by the utility model is to overcome the deficiencies of the prior art and provide a platelet-rich plasma preparation device which is easy to operate, has high preparation efficiency, can flexibly and stably adjust the preparation process and has a small amount of mixed red blood cells.

[0005] The technical solution adopted by the utility model to solve the existing problems is:

[0006] A platelet-rich plasma preparation device includes a main body, the main body is provided with a first chamber, a second chamber and a connecting channel connecting the first chamber and the second chamber, an upper end cover is installed at one end of the main body close to the first chamber, and a lower end cover is installed at one end close to the second chamber, the lower end cover is spirally connected to the main body, and a screw assembly is installed on the lower end cover, the screw assembly includes a separator and a push rod assembly, the separator is fixedly connected to the push rod assembly, the push rod assembly is arranged on the screw assembly so as to be movable up and down, and the up and down movement of the push rod assembly drives the separator to control the opening or closing of the connecting channel.

[0007] Preferably, the screw assembly includes a screw body, which is a hollow structure and includes a threaded hole section and a smooth hole section inside; a screw sealing plug is installed at the upper end of the screw body, and the screw sealing plug is a hollow structure.

[0008] Preferably, the push rod assembly comprises a slender rod and a spiral push rod, the outer circumferential surface of the spiral push rod is provided with threads, one end of the slender rod is fixedly connected to the threaded end of the spiral push rod, and the other end is fixedly connected to the separator;

[0009] The slender rod penetrates the screw body and the screw sealing plug, and the slender rod abuts against the inner surface of the screw sealing plug. One end of the spiral push rod with a thread is located inside the screw body, and the other end extends out of the screw body.

[0010] Preferably, the separator comprises an isolation plug, an isolation rubber plug is sleeved on the outer surface of the isolation plug, and the lower end surface of the isolation plug abuts against the upper end surface of the screw sealing plug.

[0011] Preferably, a piston is sleeved on the screw body, the outer circumferential surface of the piston is sealedly connected to the second chamber, the inner circumferential surface is sealedly connected to the screw body, and the lower surface is in contact with the lower end cover.

[0012] Preferably, the upper end cover includes an insertion portion for injecting blood into the main body;

[0013] An extraction part, used for extracting plasma from the subject;

[0014] The exhaust member is used to exhaust the air in the main body.

[0015] Compared with the prior art, the utility model has the following beneficial effects:

[0016] The utility model has flexible design, convenient operation and high preparation efficiency. The spiral design between the lower end cover and the main body allows the axial movement distance to be accurately controlled by rotating the lower end cover, ensuring the accuracy of the boundaries of each layer and flexibly adapting to individual differences.

[0017] The sliding connection between the slender rod and the inner surface of the screw sealing plug limits the radial freedom of the slender rod and ensures the stability of the device;

[0018] The slender rod-shaped structure of the slender rod can effectively reduce the mixing of red blood cells into the first chamber. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a structural diagram of a platelet-rich plasma preparation device of the utility model;

[0020] Figure 2 This is a full cross-sectional view of a platelet-rich plasma preparation device of the utility model;

[0021] Figure 3 This is a partial enlarged view of point A in the full cross-sectional view of a platelet-rich plasma preparation device of the utility model.

[0022] In the figure:

[0023] 1. Upper end cover, 101. Insertion part, 102. Extraction part, 103. Exhaust part, 2. Main body, 201. First chamber, 202. Connecting channel, 203. Second chamber, 3. Lower end cover, 4. Screw assembly, 401. Screw body, 40101. Threaded hole section, 40102. Light hole section, 402. Screw sealing plug, 403. Isolation plug, 404. Isolation rubber plug, 405. Slender rod, 406. Screw push rod, 5. Piston. DETAILED DESCRIPTION

[0024] This specification and claims do not use differences in names as a way to distinguish components, but use differences in components' functions as the criteria for distinction. In the description of the present utility model, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "horizontal", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model. In the present utility model, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix", etc. should be understood in a broad sense, and ordinary technicians in this field can understand the specific meanings of the above terms in the present utility model according to the specific circumstances.

[0025] like Figure 1-Figure 3 The platelet-rich plasma preparation device shown includes a main body 2 , wherein the main body 2 is provided with a first chamber 201 , a second chamber 203 , and a connecting channel 202 connecting the first chamber 201 and the second chamber 203 .

[0026] An upper end cap 1 is installed at one end of the main body 2 close to the first chamber 201, and the upper end cap 1 includes an insertion portion 101, an extraction portion 102, and an exhaust member 103. The insertion portion 101 is used to inject blood into the main body 2, the extraction portion 102 is used to extract plasma in the main body 2, and the exhaust member 103 is used to exhaust the air in the main body 2 when liquid is injected into the main body 2 through the insertion portion 101. A lower end cap 3 is installed at one end of the main body 2 close to the second chamber 203, and the lower end cap 3 is spirally connected to the main body 2, so as to realize the up and down movement of the lower end cap 3 on the main body 2, and the lower end cap 3 is installed with a screw assembly 4, and the up and down movement of the lower end cap 3 drives the screw assembly 4 to move up and down.

[0027] The screw assembly 4 includes a separator and a push rod assembly. The separator is fixedly connected to the push rod assembly. The push rod assembly is movably arranged on the screw assembly 4. The up and down movement of the push rod assembly drives the separator to move up and down, thereby controlling the opening or closing of the connecting channel 202.

[0028] The screw assembly 4 includes a screw body 401, which is a hollow structure and includes a threaded hole section 40101 and a light hole section 40102. A screw sealing plug 402 is installed at the upper end of the screw body 401, and the screw sealing plug 402 is a hollow structure.

[0029] The push rod assembly includes a slender rod 405 and a screw push rod 406. The outer circumferential surface of the screw push rod 406 is provided with threads. One end of the slender rod 405 is fixedly connected to the threaded end of the screw push rod 406, and the other end of the slender rod 405 is fixedly connected to the separator. The slender rod 405 penetrates the screw body 401 and the screw sealing plug 402, and the slender rod 405 abuts against the inner surface of the screw sealing plug 402. The threaded end of the screw push rod 406 is located at the light hole section 40102 of the screw body 401, and the other end extends out of the screw body 401.

[0030] The separator includes an isolation plug 403, an isolation rubber plug 404 is sleeved on the outer surface of the isolation plug 403, and the lower end surface of the isolation plug 403 abuts against the upper end surface of the screw sealing plug 402, thereby limiting the axial position of the separator and the push rod assembly.

[0031] The screw body 401 is sleeved with a piston 5, which is an elastomeric structure. The outer cylindrical surface of the piston 5 is sealed with the second chamber 203, the inner cylindrical surface is sealed with the screw body 401, and the lower surface is in contact with the lower end cover 3. The piston 5 is sealed with the second chamber 203 and the screw body 401 to prevent leakage of liquid.

[0032] The outer surface of the main body 2 is marked with scale lines to facilitate accurate injection and extraction of the required dose.

[0033] The working principle of the platelet-rich plasma preparation device is as follows:

[0034] When in use, firstly, the collected blood sample is injected into the main body 2 through the insertion portion 101 of the upper end cover 1, and all the blood is concentrated in the first chamber 201, the connecting channel 202 and the second chamber 203. Then, the entire device is safely placed in a centrifuge for centrifugal treatment. After centrifugation, the blood will be clearly divided into three layers: the lower layer is the red blood cell layer, the middle layer is the white film layer, and the upper layer is the plasma layer.

[0035] Next, the lower end cover 3 is rotated to gradually move upward along the axial direction. During this process, the lower end cover 3 drives the screw assembly 4 and the piston 5 to move upward, and the separator of the screw assembly 4 gradually approaches the connecting channel 202. The volume of the second chamber 203 gradually decreases as the screw assembly 4 and the piston 5 move upward. The red blood cell layer, the white film layer and the plasma layer originally located therein begin to slowly flow into the first chamber 201 under the action of the thrust. When the white film layer completely enters the interior of the connecting channel 202, the adjustment action of the lower end cover 3 stops. The spiral design between the lower end cover 3 and the main body 2 allows the axial movement distance of the lower end cover 3 to be accurately controlled by rotating it. Since the blood component ratios of different patients may be different, the thickness of the red blood cell layer, the white film layer and the plasma layer may be different. This design allows the operator to fine-tune the position of the lower end cover according to actual needs, ensure that the white film layer can fully enter the connecting channel, ensure the accuracy of the boundaries of each layer, and flexibly adapt to individual differences.

[0036] Then, the spiral push rod 406 is pushed upward, and the spiral push rod 406 drives the slender rod 405 to move upward. At this time, the slender rod 405 forms a sliding connection with the screw sealing plug 402, and the slender rod 405 drives the separator to move upward and separate from the screw sealing plug 402. When the thread of the spiral push rod 406 is engaged with the threaded hole section 40101 of the screw body 401, the pushing action should be switched to the knob action at this time. By rotating, the separator, i.e., the isolation plug 403 and the isolation rubber plug 404, completely enter the connecting channel 202 until it is completely closed. In this way, the main body 2 is divided into two parts that are not connected to each other. The second chamber 203 only contains the red blood cell layer, and the white film layer and the plasma layer have entered the first chamber 201 as expected.

[0037] During the upward movement of the screw push rod 406, the slender rod 405 and the separator, the radial freedom of the slender rod 405 is limited due to the sliding connection between the slender rod 405 and the inner surface of the screw seal plug 402, thereby ensuring that the screw push rod 406, the slender rod 405 and the separator will not shake left and right during the upward movement, thereby ensuring the stability of the device. At the same time, the slender rod-shaped structure of the slender rod 405 can effectively reduce the mixing of red blood cells into the first chamber 201 and reduce the interference with the blood components in the first chamber 201 due to the small space occupied by the slender rod 405 during the process of the separator completely entering the connecting channel 202.

[0038] If the concentration of the plasma layer needs to be further increased, the device can be placed in a centrifuge again for centrifugation. After this centrifugation, the concentration of the plasma layer will be effectively increased. Subsequently, according to specific usage requirements, an appropriate amount of plasma is extracted from the extraction part 102, and then the remaining plasma is mixed with the buffy coat layer to ensure the appropriate concentration of the sample, thereby completing the entire blood component separation and extraction process and obtaining the required blood component sample.

[0039] The implementation modes of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above implementation modes, and various changes can be made within the knowledge scope of ordinary technicians in the relevant technical field without departing from the purpose of the present invention.

Claims

1. A platelet-rich plasma preparation device, comprising a main body (2), the main body (2) being provided with a first chamber (201), a second chamber (203), and a connecting passage (202) connecting the first chamber (201) and the second chamber (203), an upper end cover (1) being installed at one end of the main body (2) close to the first chamber (201), and a lower end cover (3) being installed at one end of the main body (2) close to the second chamber (203), wherein: The lower end cover (3) is spirally connected to the main body (2), and a screw assembly (4) is installed on the lower end cover (3). The screw assembly (4) comprises a separator and a push rod assembly. The separator is fixedly connected to the push rod assembly. The push rod assembly is arranged on the screw assembly (4) so ​​as to be movable up and down. The push rod assembly drives the separator to move up and down to control the opening or closing of the connecting channel (202).

2. The platelet-rich plasma preparation device according to claim 1, characterized in that: The screw assembly (4) comprises a screw body (401), the screw body (401) being a hollow structure, and comprising a threaded hole section (40101) and a smooth hole section (40102) inside; a screw sealing plug (402) is installed at the upper end of the screw body (401), and the screw sealing plug (402) is a hollow structure.

3. The platelet-rich plasma preparation device according to claim 2, characterized in that: The push rod assembly comprises a slender rod (405) and a spiral push rod (406); the spiral push rod (406) has a threaded outer surface; one end of the slender rod (405) is fixedly connected to the threaded end of the spiral push rod (406); and the other end is fixedly connected to the separator; The slender rod (405) passes through the screw body (401) and the screw sealing plug (402), and the slender rod (405) abuts against the inner surface of the screw sealing plug (402). The screw push rod (406) has a threaded end located in the light hole section (40102) of the screw body (401), and the other end extends out of the screw body (401).

4. The platelet-rich plasma preparation device according to claim 3, characterized in that: The separator comprises an isolation plug (403), the outer surface of which is sleeved with an isolation rubber plug (404), and the lower end surface of the isolation plug (403) is in contact with the upper end surface of the screw sealing plug (402).

5. The platelet-rich plasma preparation device according to claim 4, characterized in that: The screw body (401) is sleeved with a piston (5), the outer circumferential surface of the piston (5) is sealedly connected to the second chamber (203), the inner circumferential surface is sealedly connected to the screw body (401), and the lower surface is in contact with the lower end cover (3).

6. The platelet-rich plasma preparation device according to claim 1, characterized in that: The upper end cover (1) comprises an insertion portion (101) for injecting blood into the main body (2); An extraction part (102) for extracting plasma from the main body (2); The exhaust member (103) is used to exhaust the air in the main body (2).

Images