Ultrafiltration centrifuge tube for processing trace samples

Abstract

The utility model discloses an ultrafiltration centrifuge tube for processing trace samples, which comprises an outer tube, an inner tube and an ultrafiltration component which are coaxial with the outer tube are arranged in the outer tube, the inner tube is a hollow tube with two open ends and is positioned between the outer tube and the ultrafiltration component, a plurality of bulges are uniformly distributed on the inner wall of the inner tube in the circumferential direction, and the bulges are communicated with the outer tube. The two ends of each protrusion extend to the two opening ends of the inner pipe in the axial direction of the inner pipe respectively, a flow guide groove is formed between every two adjacent protrusions, and the ultrafiltration assembly comprises a tubular ultrafiltration membrane and an installation frame used for installing the ultrafiltration membrane. According to the utility model, the ultrafiltration membrane is circumferentially arranged in the outer tube and is wound into the tubular structure, so that the effective filtering area of the ultrafiltration membrane in contact with liquid is maximized under the condition that the volume of the ultrafiltration centrifugal tube is limited, and the problems of low concentration efficiency and low centrifugal speed of the existing trace ultrafiltration centrifugal tube are solved. Meanwhile, the ultrafiltration membrane is of a tubular structure coaxial with the outer tube, so that when a sample is centrifuged, the sample tangentially flows on the surface of the ultrafiltration membrane, and the filtering effect is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of ultrafiltration centrifuge tubes, and more specifically, to an ultrafiltration centrifuge tube for processing trace samples. Background Art

[0002] Centrifugation technology has been widely used in the field of biological science, especially in biochemical and molecular biology research. Centrifuge tubes are important equipment in centrifugation technology, generally being tubular containers with lids. An ultrafiltration centrifuge tube is provided with an ultrafiltration membrane inside the centrifuge tube, and the ultrafiltration membrane can play a role in intercepting particles, realizing the rapid separation of particles and solutions.

[0003] Currently, the existing ultrafiltration centrifuge tubes for processing trace samples on the market have a small size, which greatly limits the effective filtration area of the ultrafiltration membrane. Too small an area will affect the concentration efficiency and centrifugation speed of the samples.

[0004] Therefore, a new solution needs to be proposed to solve the above problems. Summary of the Utility Model

[0005] The purpose of the utility model is to overcome the deficiencies of the above-mentioned prior art and provide an ultrafiltration centrifuge tube for processing trace samples.

[0006] To achieve the above purpose, the utility model adopts the following technical solutions:

[0007] An ultrafiltration centrifuge tube for processing trace samples includes an outer tube that is open at one end, closed at the other end, and hollow. An inner tube and an ultrafiltration component coaxial with the outer tube are arranged inside the outer tube. The inner tube is a hollow tube with both ends open and is located between the outer tube and the ultrafiltration component. A plurality of protrusions are circumferentially and uniformly distributed on the inner wall of the inner tube. Both ends of the protrusions extend along the axial direction of the inner tube to the two open ends of the inner tube respectively. A diversion groove is formed between adjacent two protrusions. The ultrafiltration component is a hollow tubular structure that is open at one end and closed at the other end. The ultrafiltration component includes a tubular ultrafiltration membrane and a mounting frame for mounting the ultrafiltration membrane.

[0008] Further, the mounting frame includes a first mounting ring, a mounting plate, and support ribs arranged between the first mounting ring and the mounting plate. The first mounting ring and the mounting plate are respectively located at both ends of the ultrafiltration membrane. A plurality of support ribs are provided and are distributed circumferentially along the ultrafiltration membrane. Both ends of the support ribs extend along the axial direction of the ultrafiltration membrane to both ends of the ultrafiltration membrane respectively and are fixedly connected to the first mounting ring and the mounting plate respectively.

[0009] Further, the mounting plate is located in the middle of the outer tube. The mounting plate protrudes outward and forms an arc-shaped structure, and is concave inward at its center.

[0010] Further, a second mounting ring is provided at one end of the inner tube, and the second mounting ring abuts against the open end of the outer tube.

[0011] Furthermore, an installation groove for installing the ultrafiltration component is formed on the second installation ring.

[0012] Furthermore, a connection component is installed on the outer wall at the open end of the outer tube, and a sealing plug is connected through the connection component.

[0013] Furthermore, the connection component includes a collar and a connecting strip. The collar is sleeved on the open end of the outer tube, one end of the connecting strip is connected to the collar, and the other end of the connecting strip is connected to the sealing plug.

[0014] Furthermore, the protrusion has a triangular prism structure.

[0015] The beneficial effects of the present utility model are as follows:

[0016] 1. In the present utility model, by circumferentially arranging the ultrafiltration membrane inside the outer tube and winding it into a tubular structure, the effective filtration area in contact with the liquid of the ultrafiltration membrane is maximized under the limited volume of the ultrafiltration centrifuge tube, so as to solve the problems of low concentration efficiency and slow centrifugation speed of the existing micro ultrafiltration centrifuge tube. At the same time, the ultrafiltration membrane has a tubular structure coaxial with the outer tube, so that when the sample is centrifuged, the sample flows tangentially on the surface of the ultrafiltration membrane, improving the filtration effect.

[0017] 2. In the present utility model, the mounting plate protrudes outward and forms an arc-shaped structure, and its center is concave. This design is for the dead volume design of the centrifuge tube to facilitate the recovery of the concentrated liquid. Description of the Drawings

[0018] Figure 1 It is a schematic structural diagram of the ultrafiltration centrifuge tube in this embodiment;

[0019] Figure 2 It is an exploded structural diagram of the ultrafiltration centrifuge tube in this embodiment;

[0020] Figure 3 It is a schematic cross-sectional structure diagram of the outer tube in this embodiment;

[0021] Figure 4 It is a schematic structural diagram of the ultrafiltration component in this embodiment;

[0022] Figure 5 It is a schematic structural diagram of the mounting rack in this embodiment;

[0023] Figure 6 It is a schematic cross-sectional structure diagram of the mounting rack in this embodiment;

[0024] Figure 7 It is a schematic structural diagram of the inner tube in this embodiment;

[0025] Figure 8This is a schematic cross-sectional structure diagram of the inner tube in this embodiment.

[0026] Reference numerals: outer tube 1, inner tube 2, protrusion 201, diversion groove 202, second mounting ring 203, mounting groove 204, ultrafiltration component 3, ultrafiltration membrane 301, mounting frame 302, first mounting ring 3021, mounting plate 3022, support rib 3023, connection component 4, collar 401, connection bar 402, sealing plug 5. Specific embodiments

[0027] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0028] Embodiment: An ultrafiltration centrifuge tube for processing trace samples, as Figures 1-8 shown, includes an outer tube 1 that is open at one end, closed at the other end, and hollow. An inner tube 2 and an ultrafiltration component 3 coaxial with the outer tube 1 are provided inside the outer tube 1. The inner tube 2 is a hollow tube with both ends open and is located between the outer tube 1 and the ultrafiltration component 3. A plurality of protrusions 201 are circumferentially and evenly distributed on the inner wall of the inner tube 2. The two ends of the protrusion 201 extend along the axial direction of the inner tube 2 to the two open ends of the inner tube 2 respectively. A diversion groove 202 is formed between adjacent two protrusions 201. The ultrafiltration component 3 is a hollow tubular structure that is open at one end and closed at the other end. The ultrafiltration component 3 includes a tubular ultrafiltration membrane 301 and a mounting frame 302 for mounting the ultrafiltration membrane 301. Among them, the outer tube 1, the inner tube 2, and the mounting frame 302 are made of plastic, and the maximum capacity of the outer tube 1 is 2 ml.

[0029] During use, the inner tube 2 is installed inside the outer tube 1, the ultrafiltration component 3 is installed inside the inner tube 2, and the open end of the ultrafiltration component 3 corresponds to the open end of the outer tube 1, and the closed end of the ultrafiltration interval corresponds to the closed end of the outer tube 1. Then, a certain amount of sample is injected into the ultrafiltration component 3. When the ultrafiltration centrifuge tube is centrifuged, the sample is filtered by the ultrafiltration membrane 301 to form a filtrate, and the filtrate flows into the outer tube 1 along the diversion groove 202 on the inner tube 2, and the concentrated solution formed by being intercepted by the ultrafiltration membrane 301 remains inside the ultrafiltration component 3.

[0030] By circumferentially arranging the ultrafiltration membrane 301 inside the outer tube 1 and winding it into a tubular structure, the effective filtration area of the ultrafiltration membrane 301 in contact with the liquid is maximized under the limited volume of the ultrafiltration centrifuge tube, so as to solve the problems of low concentration efficiency and slow centrifugation speed of the existing trace ultrafiltration centrifuge tube. At the same time, the ultrafiltration membrane 301 is a tubular structure coaxial with the outer tube 1, so that when the sample is centrifuged, the sample flows tangentially on the surface of the ultrafiltration membrane 301, improving the filtration effect.

[0031] Further, the ultrafiltration membrane 301 abuts against the protrusion 201 on the inner tube 2. The protrusion 201 can support the ultrafiltration membrane 301 to prevent the ultrafiltration membrane 301 from deforming under centrifugal force. Preferably, the protrusion 201 has a triangular prism structure. With the above design, using its inclined surface, it plays a certain guiding role for the filtrate so as to facilitate the flow of the filter element into the outer tube 1.

[0032] Further, as Figures 4-6 shown, the mounting frame 302 includes a first mounting ring 3021, a mounting plate 3022, and support ribs 3023 arranged between the first mounting ring 3021 and the mounting plate 3022. The first mounting ring 3021 and the mounting plate 3022 are respectively located at both ends of the ultrafiltration membrane 301. A plurality of support ribs 3023 are provided and are distributed circumferentially along the ultrafiltration membrane 301. Both ends of the support ribs 3023 extend axially to both ends of the ultrafiltration membrane 301 along the ultrafiltration membrane 301 and are respectively fixedly connected to the first mounting ring 3021 and the mounting plate 3022.

[0033] When the ultrafiltration module 3 and the inner tube 2 are installed in the outer tube 1, the first mounting ring 3021 of the ultrafiltration module 3 is located at the open end of the outer tube 1, the mounting plate 3022 is located in the middle of the outer tube 1, and there is a certain distance between the mounting plate 3022 and the closed end of the outer tube 1. Four support ribs 3023 are provided and are evenly distributed circumferentially along the ultrafiltration membrane 301. The ultrafiltration membrane 301 is located between the first mounting ring 3021 and the mounting plate 3022. The ultrafiltration membrane 301 is wound around the outside of the four support ribs 3023 and forms a tubular shape. Among them, the support ribs 3023 support the ultrafiltration membrane 301 and are fixedly connected to the first mounting ring 3021 and the mounting plate 3022 to form an integral body, so as to improve the strength of the entire mounting frame 302 and prevent the ultrafiltration membrane 301 and the entire mounting frame 302 from deforming under centrifugal force.

[0034] Preferably, as Figure 6 shown, the mounting plate 3022 protrudes outward and forms an arc-shaped structure, and its center is concave, that is, the mounting plate 3022 protrudes toward the closed end of the outer tube 1, and its center protrudes a certain height, such as 1 mm, toward the open end of the outer tube 1. The mounting plate 3022 adopts the above design for the dead volume design of the centrifuge tube, so as to facilitate the recovery of the concentrated solution.

[0035] Further, as Figure 7 、 Figure 8As shown, one end of the inner tube 2 is provided with a second mounting ring 203. When the inner tube 2 is installed inside the outer tube 1, the second mounting ring 203 corresponds to the open end of the outer tube 1 and abuts against the open end of the outer tube 1. By providing the second mounting ring 203, on the one hand, it is convenient to install the inner tube 2 inside the outer tube 1 and form a support for the inner tube 2 to prevent the inner tube 2 from detaching during centrifugation and even colliding with the outer tube 1 to damage the outer tube 1; on the other hand, the strength of the inner tube 2 can be enhanced to prevent the inner tube 2 from deforming during centrifugation.

[0036] An installation groove 204 for installing the ultrafiltration module 3 is formed on the second mounting ring 203. The installation groove 204 is adapted to the first mounting ring 3021. When the ultrafiltration module 3 is installed on the inner tube 2, the first mounting ring 3021 abuts against the installation groove 204. By providing the installation groove 204, it is convenient to install the ultrafiltration module 3.

[0037] Further, as Figure 1 shown, a connection assembly 4 is installed on the outer wall at the open end of the outer tube 1, and a sealing plug 5 is connected through the connection assembly 4. By providing the sealing plug 5, on the one hand, the ultrafiltration centrifuge tube can be sealed to prevent sample leakage during centrifugation; on the other hand, the plug head of the sealing plug 5 is installed in an interference fit with the open end of the ultrafiltration module 3, and the extrusion force is used to fix the ultrafiltration module 3 and the inner tube 2 to the outer tube 1 to prevent vibration during centrifugation or detachment from the outer tube 1 due to vibration, thereby affecting the centrifugation and concentration effects. By providing the connection assembly 4, it is ensured that the sealing plug 5 is not completely separated from the outer tube 1 after being pulled out, preventing the sealing plug 5 from being lost or miscovered to cause cross-contamination.

[0038] The connection assembly 4 includes a sleeve ring 401 and a connection strip 402. The sleeve ring 401 is sleeved on the open end of the outer tube 1. One end of the connection strip 402 is connected to the sleeve ring 401, and the other end of the connection strip 402 is connected to the sealing plug 5. Among them, the connection strip 402 is made of plastic and is thinner in the middle for easy bending.

[0039] The above are only the preferred embodiments of the present invention. The protection scope of the present invention is not limited to the above embodiments. All technical solutions falling within the concept of the present invention belong to the protection scope of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and refinements should also be regarded as the protection scope of the present invention.

Claims

1. An ultrafiltration centrifuge tube for processing trace samples, comprising an outer tube (1) that is open at one end, closed at the other end, and hollow, characterized in that, Inside the outer tube (1), there is an inner tube (2) and an ultrafiltration module (3) coaxial with the outer tube (1). The inner tube (2) is a hollow tube with both ends open and is located between the outer tube (1) and the ultrafiltration module (3). A number of protrusions (201) are evenly distributed circumferentially on the inner wall of the inner tube (2). Both ends of the protrusion (201) extend axially along the inner tube (2) to the two open ends of the inner tube (2) respectively. A diversion groove (202) is formed between adjacent protrusions (201). The ultrafiltration module (3) is a hollow tubular structure with one end open and one end closed, and the ultrafiltration module (3) includes a tubular ultrafiltration membrane (301) and a mounting frame (302) for mounting the ultrafiltration membrane (301).

2. The ultrafiltration centrifuge tube for processing trace samples according to claim 1, characterized in that, The mounting frame (302) includes a first mounting ring (3021), a mounting plate (3022), and support ribs (3023) provided between the first mounting ring (3021) and the mounting plate (3022). The first mounting ring (3021) and the mounting plate (3022) are respectively located at both ends of the ultrafiltration membrane (301). A plurality of support ribs (3023) are provided and are distributed circumferentially along the ultrafiltration membrane (301). Both ends of the support rib (3023) extend axially along the ultrafiltration membrane (301) to both ends of the ultrafiltration membrane (301) respectively and are fixedly connected to the first mounting ring (3021) and the mounting plate (3022) respectively.

3. The ultrafiltration centrifuge tube for processing trace samples according to claim 2, wherein The mounting plate (3022) is located in the middle of the outer tube (1). The mounting plate (3022) protrudes outward and forms an arc-shaped structure, and its center is concave inward.

4. The ultrafiltration centrifuge tube for processing trace samples according to claim 1, wherein One end of the inner tube (2) is provided with a second mounting ring (203), and the second mounting ring (203) abuts against the open end of the outer tube (1).

5. The ultrafiltration centrifuge tube for processing trace samples according to claim 2, wherein, An installation groove (204) for installing the ultrafiltration module (3) is provided on the second mounting ring (203).

6. The ultrafiltration centrifuge tube for processing trace samples according to claim 1, wherein A connection component (4) is installed on the outer wall at the open end of the outer tube (1), and a sealing plug (5) is connected through the connection component (4).

7. The ultrafiltration centrifuge tube for processing trace samples according to claim 6, wherein, The connection component (4) includes a collar (401) and a connection strip (402). The collar (401) is sleeved on the open end of the outer tube (1). One end of the connection strip (402) is connected to the collar (401), and the other end of the connection strip (402) is connected to the sealing plug (5).

8. The ultrafiltration centrifuge tube for processing trace samples according to claim 1, wherein, The protrusion (201) has a triangular prism structure.

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