Auxiliary device for chromatography test strip assembling and sample adding
By designing an auxiliary device for assembly and sample filling for chromatographic test strips, the problem of inaccurate sticking position of the test strip assembly and the movement of the test strip position during the sample filling process is solved, and the accurate positioning of the test strip assembly and the stability of the sample filling process is achieved, ensuring the accuracy of the experimental results.
Patent Information
- Application Number
- CN202421197357.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-29
- Publication Date
- 2025-05-09
- Estimated Expiration
- 2034-05-29
AI Technical Summary
During the assembly and sample loading process, the sticking position of the components of the strip is inaccurate, which leads to the impact of the performance of the strip; during the sample loading process, the position of the strip is moved or the sample overflows, resulting in deviations in the experimental results.
An auxiliary device for assembling and filling chromatographic test strips is designed, including assembly and fixing mechanism and filling and fixing mechanism. The assembly fixing mechanism ensures the accurate adhesion position of the NC film and the gold standard pad through the positioning assembly and moving the fixing rod; the sample fixing mechanism fixes the test strips through the limiting plate and the crossbar and prevents their position from moving.
Through this device, the accurate sticking position of the test strip assembly is ensured, the position of the PVC base plate is offset during assembly, and the waste of consumables is reduced; during the sample filling process, the position of the test strip is fixed, the sample overflow or erosion is avoided, and the accuracy of the experimental results is ensured.
Smart Images
Figure CN222850622U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of biological detection, and in particular relates to an auxiliary device for assembling and adding samples of a chromatography test strip. Background Art
[0002] The colloidal gold test strip is mainly composed of four parts: sample pad, gold label pad, nitrocellulose membrane (NC membrane), and absorbent paper. From bottom to top, they are connected end to end and pasted on the PVC base plate. When assembling a conventional large plate, the size of the PVC base plate used is generally 8*30cm, the nitrocellulose membrane is 2.5*30cm, and the gold pad is 0.5*30cm. The gold pad needs to be strictly pasted 1~2mm from the lower edge of the nitrocellulose membrane. If the contact length between the two is too large or too small, it will affect the performance of the test strip. Because the two are long and narrow, it is easy for the experimenter to stick the nitrocellulose membrane and the gold pad off during the assembly of the immunochromatographic test strip card, resulting in the abandonment of the large plate and the waste of cost. In addition, during the sample addition process, if the sample addition speed of the flat test strip is too fast, the sample can easily be directly washed over the gold pad, or if the operator is a little careless, the sample can easily overflow from the sample pad and cause leakage, which will cause insufficient contact between the antigen and the antibody, resulting in deviations in the experimental results. For this reason, it is necessary to propose an auxiliary device for assembling and adding samples of a chromatography test strip card. Summary of the invention
[0003] In order to solve the deficiencies of the prior art, the purpose of the utility model is to provide an auxiliary device for assembling and adding samples of chromatography test strips, which has a simple structure and is easy to use. It can ensure the accuracy of the pasting position of each component and avoid the movement of the test strip during the adding sample process, thereby ensuring the accuracy of the experiment.
[0004] In order to achieve the above objectives, the utility model adopts the following technical solutions:
[0005] The cam is an angular contact surface that is fixed to the top of the base and has a plurality of interlocking members, each of which is engaged with the second cam and is engaged with the second cam, and the plurality of interlocking members are engaged with the second cam.
[0006] Preferably, two first positioning rods are provided, both of which are L-shaped structures and are symmetrical about the center of the rear fixing bar. A moving rod is vertically fixed to the rear side of the first positioning rod.
[0007] Preferably, both sides of the aforementioned rear fixing strip are provided with through holes passing through both ends thereof and a first threaded hole vertically connected to the middle of the through hole. The movable rod is movable through the through hole. The first threaded hole is threadedly connected with a first bolt, which is screwed in until its bottom abuts against the top of the movable rod to fix the movable rod.
[0008] Preferably, the aforementioned sample loading and fixing mechanism includes a plurality of first limiting plates and cross bars fixed at equal intervals on the front fixing bar, mounting blocks are fixed on both sides of the top of the front fixing bar, limiting grooves are provided on the inner upper part of the mounting blocks, and the two ends of the cross bar are respectively inserted into the limiting grooves of the two mounting blocks, and a second threaded hole is provided on the top of the mounting block, in which a second bolt is threadedly connected, and the two second bolts are screwed in until their bottoms are against the cross bar to fix the cross bar.
[0009] Preferably, a plurality of second limiting plates are vertically fixed at equal intervals on the front side of the aforementioned crossbar, and the second limiting plate is located between two adjacent first limiting plates, and forms a test strip fixing cavity with the first limiting plate on its left side.
[0010] Preferably, a third threaded hole is provided on the outer side of the aforementioned sliding block, a third bolt is threadedly connected in the third threaded hole, and two third bolts are screwed in until their bottoms abut against the left fixing bar and the right fixing bar to fix the sliding block.
[0011] Preferably, the front side of the fixing rod is slidably connected to the second positioning rod.
[0012] Preferably, buckles are provided on both sides of the bottom of the base via pins.
[0013] Preferably, scale lines are provided on both sides of the top of the base.
[0014] The benefits of the utility model are as follows: the utility model has a simple structure and is easy to use. The PVC base plate can be accurately positioned through the positioning component. By moving the fixing rod, not only can the accuracy of the pasting position of the NC film and the gold label pad be guaranteed, but also the position deviation of the PVC base plate during the assembly process can be avoided, thereby avoiding waste of consumables. By moving the cross bar, the first limiting plate and the second limiting plate can fix the test strip to avoid the movement of the test strip during the sample addition process. The buckle is opened to tilt the base, which can effectively avoid sample overflow or direct flushing, thereby causing deviation in the experimental results, thereby ensuring the accuracy of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 It is a structural schematic diagram of the utility model;
[0016] Figure 2 It is a schematic diagram of the utility model when it is in a sample adding state;
[0017] Figure 3 is a cross-sectional view of the mounting block in the utility model;
[0018] Figure 4 It is a schematic diagram of the utility model when the buckle is opened.
[0019] The meanings of the reference numerals in the figure are: 1. base, 2. front fixing bar, 3. rear fixing bar, 4. left fixing bar, 5. right fixing bar, 6. first positioning rod, 7. fixing rod, 8. left vertical plate, 9. right vertical plate, 10. first guide block, 11. slider, 12. moving rod, 13. first bolt, 14. first limiting plate, 15. cross bar, 16. mounting block, 161. limiting groove, 17. second bolt, 18. second limiting plate, 19. third bolt, 20. second positioning rod, 21. buckle, 22. scale line, 23. PVC bottom plate, 24. test strip. DETAILED DESCRIPTION
[0020] The present invention is described in detail below with reference to the accompanying drawings and specific embodiments.
[0021] See also Figure 1 The utility model discloses an auxiliary device for assembling and adding samples of a chromatography test strip, comprising a base 1, an assembly fixing mechanism and a sample adding fixing mechanism are arranged on the top of the base 1, and scale lines 22 are arranged on both sides of the top of the base 1.
[0022] The assembly fixing mechanism includes a fixing bar assembly, a positioning assembly and a fixing assembly. The fixing bar assembly includes a front fixing bar 2, a rear fixing bar 3, a left fixing bar 4 and a right fixing bar 5 respectively fixed at the edges of the top of the base 1. The positioning assembly includes a first positioning rod 6 arranged on the rear fixing bar 3. Two first positioning rods 6 are provided, both of which are L-shaped structures and are symmetrical about the center of the rear fixing bar 3. A moving rod 12 is vertically fixed to the rear side of the first positioning rod 6. By moving the two first positioning rods 6 forward and backward, the position of the PVC bottom plate can be adjusted. Both sides of the rear fixing bar 3 are provided with through holes penetrating the two ends thereof and a first threaded hole vertically connected to the middle of the through hole. The moving rod 12 movably passes through the through hole. The first threaded hole is threadedly connected to a first bolt 13. The first bolt 13 is screwed in until its bottom abuts against the top of the moving rod 12 to fix the moving rod 12.
[0023] The fixing assembly includes a fixing rod 7, a left vertical plate 8 and a right vertical plate 9. The inner sides of the left vertical plate 8 and the right vertical plate 9 are both provided with a first slide groove perpendicular to the base 1. The two ends of the fixing rod 7 are slidably connected in the first slide groove through the first guide block 10 to drive the fixing rod 7 to move up and down. The fixing rod 7 moves downward to press the PVC bottom plate 23 to avoid the position of the PVC bottom plate 23 from being offset during the assembly process and to avoid wasting consumables. The outer sides of the left vertical plate 8 and the right vertical plate 9 are both fixedly connected to the slider 11. The lower part of the slider 11 is provided with a second slide groove. The second slide grooves of the two sliders 11 are respectively slidably connected with the left vertical plate 8 and the right vertical plate 9 to drive the forward and backward movement of the fixing rod 7. Through the forward and backward movement of the fixing rod 7, in conjunction with the scale line 22, the position where the NC film and the gold label pad are pasted can be accurately located. The outer side of the slider 11 is provided with a third threaded hole, and the third bolt 19 is threadedly connected in the third threaded hole. The two third bolts 19 are screwed in until their bottoms are against the left fixing bar 4 and the right fixing bar 5 to fix the slider 11.
[0024] The front side of the fixing rod 7 is slidably connected to the second positioning rod 20. By moving the second positioning rod 20 left and right, the left side of the NC film and the gold label pad can be positioned, thereby improving the accuracy of the pasting position.
[0025] See also Figure 2 and Figure 3 The sample loading and fixing mechanism includes a plurality of first limiting plates 14 and a cross bar 15 fixed at equal intervals on the front fixing bar 2. Mounting blocks 16 are fixed on both sides of the top of the front fixing bar 2. A limiting groove 161 is provided on the inner upper part of the mounting block 16. The two ends of the cross bar 15 are respectively inserted into the limiting grooves 161 of the two mounting blocks 16. A second threaded hole is provided on the top of the mounting block 16. The second threaded hole is threaded with a second bolt 17. The two second bolts 17 are screwed in until their bottoms abut against the cross bar 15 to fix the cross bar 15. A plurality of second limiting plates 18 are fixed vertically at equal intervals on the front side of the cross bar 15. The second limiting plate 18 is located between two adjacent first limiting plates 14, and forms a test strip 24 fixing cavity with the first limiting plate 14 on its left side. By moving the cross bar 15, the first limiting plate 14 and the second limiting plate 18 can fix the test strip 24 to prevent the test strip 24 from moving during the sample addition process. The distance between the first limiting plate 14 and the second limiting plate 18 can be adjusted, which is conducive to adapting to test strips 24 of different widths.
[0026] See also Figure 4 Both sides of the bottom of the base 1 are provided with buckles 21 through pins. By prying open the rotatable buckles 21 on the back of the base 1, the base 1 forms a certain inclination with the experimental desktop, which can alleviate the problem that the sample is directly flushed to the nitrocellulose membrane when the test strip 24 is placed flat, resulting in insufficient contact between the antibody and the antigen, thereby causing deviation in the experimental results.
[0027] In order to better illustrate the utility model, the working process is described in detail below:
[0028] During assembly, adjust the positions of the two first positioning rods 6, place the PVC base plate 23, move the front edge of the fixing rod 7 to the specified scale line 22, move it downward to press the PVC base plate 23, adjust the second positioning rod 20 to the appropriate position, paste the NC film, and paste the gold label pad, sample pad, etc. according to the same steps. After assembly, cut it to obtain the test strip 24.
[0029] Before adding samples, first open the buckle 21 to tilt the base 1, then place multiple test strips 24 on the front fixing bar 2 in sequence, move the cross bar 15 so that the first limiting plate 14 and the second limiting plate 18 fix the test strips 24, and then start adding samples for testing.
[0030] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the above embodiments do not limit the utility model in any form, and any technical solution obtained by equivalent replacement or equivalent transformation falls within the protection scope of the utility model.
Claims
1. An auxiliary device for assembling and adding samples to a chromatography test strip, comprising a base (1), characterized in that: The top of the base (1) is provided with an assembly fixing mechanism and a sample loading fixing mechanism. The assembly fixing mechanism comprises a fixing bar assembly, a positioning assembly and a fixing assembly. The fixing bar assembly comprises a front fixing bar (2), a rear fixing bar (3), a left fixing bar (4) and a right fixing bar (5) respectively fixed at the edges of the top of the base (1). The positioning assembly comprises a first positioning rod (6) arranged on the rear fixing bar (3). The fixing assembly comprises a fixing rod (7), a left vertical plate (8) and a right vertical plate (9). The left vertical plate The inner sides of the left and right vertical plates (8) and the right vertical plate (9) are both provided with first slide grooves perpendicular to the base (1); the two ends of the fixing rod (7) are slidably connected in the first slide grooves through first guide blocks (10) to drive the fixing rod (7) to move up and down; the outer sides of the left and right vertical plates (8) and the right vertical plates (9) are both fixedly connected with sliders (11); the lower parts of the sliders (11) are provided with second slide grooves; the second slide grooves of the two sliders (11) are respectively slidably connected with the left and right vertical plates (8) and the right vertical plates (9) to drive the fixing rod (7) to move forward and backward.
2. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 1, characterized in that: Two first positioning rods (6) are provided, both of which are L-shaped structures and are symmetrical about the center of the rear fixing strip (3). A moving rod (12) is vertically fixed to the rear side of the first positioning rod (6).
3. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 2, characterized in that: Both sides of the rear fixing strip (3) are provided with through holes penetrating the two ends thereof and a first threaded hole vertically connected to the middle of the through hole, the moving rod (12) is movably passed through the through hole, a first bolt (13) is threadedly connected in the first threaded hole, and the first bolt (13) is screwed in until its bottom abuts against the top of the moving rod (12) to fix the moving rod (12).
4. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 1, characterized in that: The sample loading and fixing mechanism comprises a plurality of first limiting plates (14) and a cross bar (15) fixed at equal intervals on the front fixing bar (2); mounting blocks (16) are fixed on both sides of the top of the front fixing bar (2); limiting grooves (161) are provided on the inner upper part of the mounting blocks (16); the two ends of the cross bar (15) are respectively inserted into the limiting grooves (161) of the two mounting blocks (16); a second threaded hole is provided on the top of the mounting block (16); a second bolt (17) is threadedly connected in the second threaded hole; the two second bolts (17) are screwed in until their bottoms abut against the cross bar (15), so as to fix the cross bar (15).
5. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 4, characterized in that: A plurality of second limiting plates (18) are vertically fixed at equal intervals on the front side of the crossbar (15); the second limiting plate (18) is located between two adjacent first limiting plates (14) and forms a test strip fixing cavity with the first limiting plate (14) on its left side.
6. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 1, characterized in that: A third threaded hole is provided on the outer side of the slider (11), and a third bolt (19) is threadedly connected in the third threaded hole. Two third bolts (19) are screwed in until their bottoms abut against the left fixing bar (4) and the right fixing bar (5), so as to fix the slider (11).
7. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 1, characterized in that: The front side of the fixing rod (7) is slidably connected to the second positioning rod (20).
8. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 1, characterized in that: Buckles (21) are provided on both sides of the bottom of the base (1) via pins.
9. The auxiliary device for assembling and adding samples of a chromatography test strip according to claim 1, characterized in that: Scale lines (22) are provided on both sides of the top of the base (1).