Reaction device for drug synthesis

Abstract

The utility model discloses a reaction device for medicine synthesis, which comprises a shell, a reaction mechanism, a microwave heating mechanism, a rotating mechanism and an electric heating mechanism, a first chamber and a second chamber are respectively arranged in the shell, the reaction mechanism is arranged in the second chamber, and the microwave heating mechanism is arranged on the left side of the reaction mechanism; according to the reaction device for drug synthesis, common alternating-current electric energy is converted into direct-current electric energy through a microwave power supply and output to a magnetron, so that the magnetron generates microwaves, the microwaves irradiate a drug in a reaction barrel through cooperative use of a first circular channel, a second circular tube and a fan unit, and the microwaves periodically change an electromagnetic field, so that the drug synthesis effect is achieved. The temperature rises due to the increase of the vibration kinetic energy of water molecules, so that the medicament is heated, and the medicament is uniformly heated by utilizing the characteristic that the microwave penetrating power is relatively high, so that the chemical reaction speed of the medicament is increased.

Description

Technical Field

[0001] The utility model relates to the technical field of drug synthesis, in particular to a reaction device for drug synthesis. Background Art

[0002] After more than 30 years of development, my country has basically been able to match the raw materials needed for pharmaceutical production, with only a small part needing to be imported. Moreover, since my country has relatively abundant resources, the price of raw materials is relatively low.

[0003] The heating in the existing traditional chemical agent synthesis process mostly transfers heat from the outside to the inside to meet the thermal balance requirements of the agent synthesis. However, this method has the problem of excessive heat transfer consumption during application, and the heating time is long. Furthermore, microwave heating is used, but the agent needs to be placed in the corresponding heating device. After heating, the agent needs to be manually taken out before other agents can be placed, which reduces the relative efficiency. Secondly, some agents are not convenient to be heated using microwaves.

[0004] Therefore, the utility model provides a drug synthesis reaction device to solve the above problems. Utility Model Content

[0005] In view of the deficiencies in the prior art, the utility model provides a reaction device for drug synthesis, which solves the above problems.

[0006] To achieve the above objectives, the utility model is implemented through the following technical solutions: a reaction device for drug synthesis, comprising a shell, a first chamber and a second chamber are respectively arranged inside the shell, and also comprises a reaction mechanism, a microwave heating mechanism, a rotating mechanism and an electric heating mechanism, the reaction mechanism is arranged inside the second chamber, the microwave heating mechanism is arranged on the left side of the reaction mechanism, the rotating mechanism is arranged on the lower side of the microwave heating mechanism, and the electric heating mechanism is arranged on the right side of the reaction mechanism.

[0007] Preferably, a first notch is provided inside the shell, a first driving motor is provided inside the first notch, an output end of the first driving motor is fixedly connected to a first rotating shaft, and a connecting disk is rotatably connected to the middle of the first rotating shaft.

[0008] Preferably, one end of the first rotating shaft away from the first driving motor is rotatably connected to the inner wall of the upper end of the shell, and a connecting rod is rotatably connected to the outer side of the upper end of the first rotating shaft, one end of the connecting rod is fixedly connected to the upper end of the connecting disk, and the end of the connecting rod away from the connecting disk is fixedly connected to the inner wall of the upper side of the shell.

[0009] Preferably, a fixing ring is provided on the connecting plate, the fixing ring is configured as a circular ring sleeve, a sliding groove is provided at the upper end of the fixing ring, the sliding groove is slidably connected to the fixing ring, the inner end of the fixing ring is fixedly connected to the reaction barrel, and four second notches are provided at the bottom end of the reaction barrel.

[0010] Preferably, the microwave heating mechanism includes a microwave power supply, a magnetron, a first circular path and a microwave wave tube, the microwave power supply and the magnetron are arranged in the first chamber, the first circular path is arranged on the inner wall of the shell, one end of the first circular path is connected to the microwave wave tube, and the magnetron is fixedly connected to the microwave wave tube.

[0011] Preferably, the first circular channel connects the first chamber and the second chamber, a fan unit is arranged inside the first circular channel, a second circular tube is slidably connected to the lower side of the first circular channel, a first electric push rod is arranged on the outer side of the first circular channel, and one end of the first electric push rod is fixedly connected to the second circular tube.

[0012] Preferably, the rotating mechanism comprises a second electric rod, the second electric rod is fixedly connected to the inner wall of the bottom end of the housing, a circular plate is fixedly connected to the upper side of the second electric rod, and a second driving motor is arranged on the circular plate.

[0013] Preferably, the output end of the second driving motor is fixedly connected to a second rotating shaft, a gear is fixedly connected to the outer side of the second rotating shaft, a gear ring is threadedly connected to the outer side of the gear, a second slide groove is provided at the bottom end of the gear ring, and a round rod is slidably connected in the second slide groove.

[0014] Preferably, a telescopic groove is provided inside the gear ring, a spring is provided inside the telescopic groove, a telescopic block is slidably connected inside the telescopic groove, and the spring is fixedly connected to the telescopic block.

[0015] Preferably, the electric heating mechanism includes a third electric push rod, which is arranged inside the shell, a fixed plate is fixedly connected to the upper side of the third electric push rod, an electric heater is arranged on the upper side of the fixed plate, a fourth electric push rod is arranged inside the upper side of the shell, and a barrel cover is fixedly connected to the lower side of the fourth electric push rod.

[0016] Beneficial Effects

[0017] The utility model provides a reaction device for drug synthesis. Compared with the prior art, it has the following beneficial effects:

[0018] (1) A drug synthesis reaction device, which converts commonly used alternating current power into direct current through a microwave power supply and outputs it to a magnetron, so that the magnetron generates microwaves. The microwaves are used in conjunction with a first circular channel, a second circular tube and a fan unit to irradiate the medicine in a reaction barrel. The microwaves periodically change the electromagnetic field, causing the increase in the vibration kinetic energy of water molecules to cause the temperature to rise, causing the medicine to become hot. The microwave's strong penetrating ability is used to make the medicine evenly heated, thereby increasing the chemical reaction rate of the medicine.

[0019] (2) A drug synthesis reaction device, which has six reaction barrels arranged by a reaction mechanism, and then uses a connecting plate to rotate to drive a fixed ring to rotate, so that during the rotation and heating of the reaction barrels, different drug solutions can be placed in other reaction barrels without stopping the device, thereby improving efficiency to a certain extent.

[0020] (3) A drug synthesis reaction device, which uses microwaves generated by a magnetron to facilitate control, making heating sensitive, and conveniently adjusting the output power for different drugs. The microwaves are used to heat evenly, thereby reducing the use of solvents in drug synthesis and thus reducing environmental pollution.

[0021] (4) A drug synthesis reaction device, which uses a spring, a telescopic rod and a second notch to further evenly heat the drug in the reaction barrel.

[0022] (5) A drug synthesis reaction device, which increases the upper limit of the impact force that the inner wall of the reaction barrel can withstand through the cooperation of the barrel cover and the fixing ring, thereby increasing the service life of the entire reaction device to a certain extent. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is the overall mechanism structure diagram of the utility model;

[0024] Figure 2 This is the front view of the overall structure of the utility model;

[0025] Figure 3 The utility model Figure 2 Middle AA structure section view;

[0026] Figure 4 It is a side view of the reaction mechanism structure of the utility model;

[0027] Figure 5 It is a partial structural diagram of the reaction mechanism of the utility model;

[0028] Figure 6 This is a structural diagram of the electric heating mechanism of the utility model;

[0029] Figure 7 This is the first circular path structure diagram of the utility model;

[0030] Figure 8 It is a side view of the rotating mechanism structure of the utility model;

[0031] Fig. 9 The utility model Figure 4 Partial A map;

[0032] Fig.10 The utility model Figure 8 Partial B.

[0033] In the figure, 1, housing; 2, first chamber; 3, second chamber;

[0034] Reaction mechanism: 41, first driving motor; 42, first rotating shaft; 43, connecting rod; 44, connecting plate; 45, fixing ring; 46, reaction barrel; 47, second notch; 48, fixing ring;

[0035] Microwave heating mechanism: 51, microwave power supply; 52, magnetron; 53, first circular channel; 54, second circular tube; 55, first electric push rod; 56, fan unit;

[0036] Rotating mechanism: 61, second electric rod; 62, circular plate; 63, second driving motor; 64, second rotating shaft; 65, gear; 66, gear ring; 67, circular rod; 68, telescopic slot; 69, spring; 691, telescopic block;

[0037] Electric heating mechanism: 71, third electric push rod; 72, fixing plate; 73, electric heater; 74, fourth electric push rod; 75, barrel cover. DETAILED DESCRIPTION

[0038] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0039] Embodiment 1:

[0040] See also Figure 1-10 A drug synthesis reaction device comprises a shell 1, wherein a first chamber 2 and a second chamber 3 are respectively arranged inside the shell 1, and further comprises a reaction mechanism, a microwave heating mechanism, a rotating mechanism and an electric heating mechanism. The reaction mechanism is arranged inside the second chamber 3, the microwave heating mechanism is arranged on the left side of the reaction mechanism, the rotating mechanism is arranged on the lower side of the microwave heating mechanism, and the electric heating mechanism is arranged inside the right side of the reaction mechanism.

[0041] A first notch is provided inside the housing 1 , and a first driving motor 41 is provided inside the first notch. A first rotating shaft 42 is fixedly connected to an output end of the first driving motor 41 , and a connecting disk 44 is rotatably connected to the middle of the first rotating shaft 42 .

[0042] One end of the first rotating shaft 42 away from the first driving motor 41 is rotatably connected to the inner wall of the upper end of the shell 1, and the outer side of the upper end of the first rotating shaft 42 is rotatably connected to a connecting rod 43, one end of the connecting rod 43 is fixedly connected to the upper end of the connecting disk 44, and the end of the connecting rod 43 away from the connecting disk 44 is fixedly connected to the inner wall of the upper side of the shell 1.

[0043] A fixing ring 45 is arranged on the connecting disk 44, and the fixing ring 45 is arranged in a circular ring shape. A slide groove is arranged on the upper end of the fixing ring 45, and a fixing ring 48 is slidably connected to the slide groove. A reaction barrel 46 is fixedly connected to the inner side end of the fixing ring 48, and four second notches 47 are arranged at the bottom end of the reaction barrel 46.

[0044] The microwave heating mechanism includes a microwave power supply 51, a magnetron 52, a first circular channel 53 and a microwave wave tube. The microwave power supply 51 and the magnetron 52 are arranged in the first chamber 2, the first circular channel 53 is arranged on the inner wall of the shell 1, one end of the first circular channel 53 is connected to the microwave wave tube, and the magnetron 52 is fixedly connected to the microwave wave tube.

[0045] The first circular channel 53 connects the first chamber 2 and the second chamber 3 , a fan unit 56 is arranged inside the first circular channel 53 , a second circular tube 54 is slidably connected to the lower side of the first circular channel 53 , a first electric push rod 55 is arranged outside the first circular channel 53 , and one end of the first electric push rod 55 is fixedly connected to the second circular tube 54 .

[0046] Working process:

[0047] The medicine liquid is placed inside the reaction barrel 46, and the first driving motor 41 is started to rotate the first rotating shaft 42, which drives the connecting disk 44 to rotate, which drives the fixing ring 45 to rotate, and the fixing ring 45 drives the reaction barrel 46 to rotate. When the reaction barrel 46 is moved to the designated working position of the microwave heating mechanism, the first driving motor 41 is turned off to stop the connecting disk 44 and the fixing ring 45, while the position of the reaction barrel 46 remains fixed. The commonly used AC power source 51 is used to convert the commonly used AC power into DC power and output it to the magnetron 52, so that the magnetron 52 generates microwaves through the coordinated use of the first circular channel 53, the second circular tube 54 and the fan unit 56, so that the microwaves are irradiated to the medicine in the reaction barrel 46, and the microwaves periodically change the electromagnetic field, so that the increase of the vibration kinetic energy of the water molecules leads to an increase in temperature, so that the medicine becomes hot.

[0048] Embodiment 2:

[0049] See also Figure 1-10This embodiment provides a technical solution for a drug synthesis reaction device based on the first embodiment: the rotating mechanism includes a second electric rod 61, the second electric rod 61 is fixedly connected to the inner wall of the bottom end of the shell 1, and a circular plate 62 is fixedly connected to the upper side of the second electric rod 61, and a second driving motor 63 is arranged on the circular plate 62.

[0050] The output end of the second driving motor 63 is fixedly connected with a second rotating shaft 64, the outer side of the second rotating shaft 64 is fixedly connected with a gear 65, the outer side of the gear 65 is threadedly connected with a gear ring 66, the bottom end of the gear ring 66 is provided with a second slide groove, and a round rod 67 is slidably connected in the second slide groove.

[0051] Working process: the second electric rod 61 is extended to raise the circular plate 62, so that the inside of the gear ring 66 is engaged with the reaction barrel 46, and the telescopic block 691 is squeezed by the outer side wall of the reaction barrel 46, so that the telescopic block 691 slides inward along the telescopic groove 68, so that the telescopic block 691 squeezes the spring 69, so that the spring 69 is compressed, and the second driving motor 63 is started to rotate the second rotating shaft 64, and the rotation of the second rotating shaft 64 drives the gear 65 to rotate, and the rotation of the gear 65 drives the gear ring 66 to rotate. During the rotation of the gear ring 66, when the telescopic block 691 moves to the second notch 47 during the rotation, the telescopic block 691 is affected by the spring 69, so that the telescopic block 691 extends into the second notch 47, and the inner side wall of the telescopic block 691 is used to resist the side wall of the second notch 47, so that in the subsequent rotation, the gear ring 66 rotates to drive the reaction barrel 46 to rotate, and through the rotation of the reaction barrel 46, the medicine inside the reaction barrel 46 is heated evenly during the microwave heating process.

[0052] After heating, the power supply and the fan unit 56 connected to the microwave power supply 51 are turned off, the first electric push rod 55 is retracted, so that the second round tube 54 moves upward, the second rotating shaft 64 is turned off, and the second electric rod 61 is retracted, so that the gear ring 66 is separated from the reaction barrel 46.

[0053] Embodiment three:

[0054] See also Figure 1-10 This embodiment provides a technical solution for a drug synthesis reaction device based on the first embodiment: a telescopic groove 68 is provided inside the tooth ring 66, a spring 69 is provided inside the telescopic groove 68, a telescopic block 691 is slidably connected inside the telescopic groove 68, and the spring 69 is fixedly connected to the telescopic block 691.

[0055] The electric heating mechanism includes a third electric push rod 71, which is arranged inside the shell 1. A fixing plate 72 is fixedly connected to the upper side of the third electric push rod 71, and an electric heater 73 is arranged on the upper side of the fixing plate 72. A fourth electric push rod 74 is arranged inside the upper side of the shell 1, and a barrel cover 75 is fixedly connected to the lower side of the fourth electric push rod 74.

[0056] Working process: When the agent is unstable or explosive during the synthesis process:

[0057] The first drive motor 41 is started, and the first drive motor 41 drives the first rotating shaft 42 to rotate, so that the rotation of the first rotating shaft 42 drives the connecting disk 44 to rotate, and the connecting disk 44 drives the fixing ring 45 to rotate to the specified position of the electric heating mechanism, and the third electric push rod 71 is extended to make the fixing plate 72 rise, so that the electric heater 73 is engaged with the reaction barrel 46, and the fourth electric push rod 74 is extended to make the barrel cover 75 engage with the upper end of the second slot 47, and the electric heater 73 is started to heat the medicine in the second slot 47 through heat conduction.

[0058] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0059] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0060] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A drug synthesis reaction device, comprising a housing (1), wherein a first chamber (2) and a second chamber (3) are respectively arranged inside the housing (1), characterized in that: It also includes a reaction mechanism, a microwave heating mechanism, a rotation mechanism and an electric heating mechanism, wherein the reaction mechanism is arranged inside the second chamber (3), the microwave heating mechanism is arranged on the left side of the reaction mechanism, the rotation mechanism is arranged on the lower side of the microwave heating mechanism, and the electric heating mechanism is arranged inside the right side of the reaction mechanism.

2. A drug synthesis reaction device according to claim 1, characterized in that: A first notch is provided inside the housing (1), a first drive motor (41) is provided inside the first notch, an output end of the first drive motor (41) is fixedly connected to a first rotating shaft (42), and a connecting disk (44) is rotatably connected to the middle of the first rotating shaft (42).

3. A drug synthesis reaction device according to claim 2, characterized in that: One end of the first rotating shaft (42) away from the first driving motor (41) is rotatably connected to the inner wall of the upper end of the housing (1); a connecting rod (43) is rotatably connected to the outer side of the upper end of the first rotating shaft (42); one end of the connecting rod (43) is fixedly connected to the upper end of the connecting disk (44); and one end of the connecting rod (43) away from the connecting disk (44) is fixedly connected to the inner wall of the upper side of the housing (1).

4. A drug synthesis reaction device according to claim 3, characterized in that: The connecting disk (44) is provided with a fixing ring (45), the fixing ring (45) being arranged in the shape of a circular ring sleeve, the upper end of the fixing ring (45) being provided with a sliding groove, the sliding groove being slidably connected to a fixing ring (48), the inner side end of the fixing ring (48) being fixedly connected to a reaction barrel (46), and the bottom end of the reaction barrel (46) being provided with four second notches (47).

5. A drug synthesis reaction device according to claim 1, characterized in that: The microwave heating mechanism comprises a microwave power source (51), a magnetron (52), a first circular path (53) and a microwave wave tube; the microwave power source (51) and the magnetron (52) are arranged in a first chamber (2); the first circular path (53) is arranged on the inner wall of the housing (1); one end of the first circular path (53) is connected to the microwave wave tube; and the magnetron (52) is fixedly connected to the microwave wave tube.

6. A drug synthesis reaction device according to claim 5, characterized in that: The first circular channel (53) communicates with the first chamber (2) and the second chamber (3); a fan unit (56) is arranged inside the first circular channel (53); a second circular tube (54) is slidably connected to the lower side of the first circular channel (53); a first electric push rod (55) is arranged outside the first circular channel (53); one end of the first electric push rod (55) is fixedly connected to the second circular tube (54).

7. A drug synthesis reaction device according to claim 1, characterized in that: The rotating mechanism comprises a second electric rod (61), the second electric rod (61) being fixedly connected to the inner wall of the bottom end of the housing (1), a circular plate (62) being fixedly connected to the upper side of the second electric rod (61), and a second driving motor (63) being arranged on the circular plate (62).

8. A drug synthesis reaction device according to claim 7, characterized in that: The output end of the second driving motor (63) is fixedly connected to a second rotating shaft (64), the outer side of the second rotating shaft (64) is fixedly connected to a gear (65), the outer side of the gear (65) is threadedly connected to a gear ring (66), the bottom end of the gear ring (66) is provided with a second slide groove, and a round rod (67) is slidably connected in the second slide groove.

9. A drug synthesis reaction device according to claim 8, characterized in that: A telescopic groove (68) is provided inside the gear ring (66), a spring (69) is provided inside the telescopic groove (68), a telescopic block (691) is slidably connected inside the telescopic groove (68), and the spring (69) is fixedly connected to the telescopic block (691).

10. A drug synthesis reaction device according to claim 1, characterized in that: The electric heating mechanism comprises a third electric push rod (71), the third electric push rod (71) is arranged inside the housing (1), a fixing plate (72) is fixedly connected to the upper side of the third electric push rod (71), an electric heater (73) is arranged on the upper side of the fixing plate (72), a fourth electric push rod (74) is arranged inside the upper side of the housing (1), and a barrel cover (75) is fixedly connected to the lower side of the fourth electric push rod (74).

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