Integrated stent type artificial blood vessel

Abstract

The integrated stent type artificial blood vessel comprises an artificial blood vessel part which comprises an artificial blood vessel main branch, an artificial head-arm branch and an artificial left carotid artery branch, and the artificial head-arm branch and the artificial left carotid artery branch are arranged beside the artificial blood vessel main branch and communicated with the artificial blood vessel main branch; the covered stent is connected with the far end of the artificial blood vessel part, and the covered stent comprises a covered stent trunk and a left subclavian artery branch which is arranged beside the covered stent trunk and communicated with the covered stent trunk; the anti-regurgitation cap is arranged close to the joint of the artificial blood vessel part and the covered stent, the anti-regurgitation cap is arranged on the periphery of the far-end part of the artificial blood vessel main branch in a surrounding mode, and a cap opening of the anti-regurgitation cap faces the covered stent. According to the integrated stent type artificial blood vessel, the treatment steps and treatment time of the integrated stent type artificial blood vessel and the aortic arch anastomotic stoma are simplified, the circulation stopping time is shortened, and postoperative rehabilitation of a patient is facilitated.

Description

Technical Field

[0001] This application relates to the technical field of artificial blood vessel medical devices, and particularly to an integrated stent-type artificial blood vessel. Background Art

[0002] Currently, during traditional aortic dissection surgery, the brachiocephalic trunk branches, left common carotid artery, and left subclavian artery need to be dissected. Under circulatory arrest, an intraoperative covered stent is placed into the true lumen of the descending aorta. The covered stent and the four-branch artificial blood vessel are separately arranged. Therefore, the proximal end of the covered stent needs to be sutured to the distal end of the four-branch artificial blood vessel and the autologous aortic wall. The exposure is relatively difficult, there is backflow interference during suturing, and the dissection and suturing space is limited, increasing the anastomosis difficulty. As a result, the circulatory arrest time is prolonged, affecting the protection of the brain tissue. Moreover, the surgical operation is difficult, which easily leads to the risk of bleeding after anastomosis, prolongs the overall surgical time, increases the extracorporeal circulation time, and is not conducive to postoperative rehabilitation. Utility Model Content

[0003] This application provides an integrated stent-type artificial blood vessel, including:

[0004] An artificial blood vessel part, including an artificial blood vessel main trunk and an artificial brachiocephalic trunk branch and an artificial left carotid artery branch arranged beside the artificial blood vessel main trunk and communicating with the artificial blood vessel main trunk;

[0005] A covered stent, connected to the distal end of the artificial blood vessel part. The covered stent includes a covered stent main trunk and a left subclavian artery branch trunk arranged beside the covered stent main trunk and communicating with the covered stent main trunk;

[0006] An anti-reflux cap, arranged near the connection between the artificial blood vessel part and the covered stent. The anti-reflux cap is arranged around the outer periphery of the distal end of the artificial blood vessel main trunk, and the cap opening of the anti-reflux cap faces the covered stent.

[0007] The integrated stent-type artificial blood vessel provided by the present application has an integrated design in which the artificial blood vessel part is connected to the coated stent, which avoids the problem of difficult exposure caused by the need for the proximal end of the coated stent to be sutured with the distal end of the four-branch artificial blood vessel and the autologous aortic wall. There is no need to anastomose the stent and the artificial blood vessel during surgery, which reduces the anastomotic blood vessel time and avoids the risk of bleeding at the anastomotic site. The coated stent includes a branch of the left subclavian artery. After the autologous aorta is cut open and located between the autologous left common carotid artery and the autologous left subclavian artery, the branch of the left subclavian artery can be inserted into the autologous left subclavian artery, avoiding the freeing of the autologous left subclavian artery during the operation and avoiding the anastomosis of a branch of the artificial blood vessel with the autologous left subclavian artery, reducing the operation and reducing the operation time. The integrated stent-type artificial blood vessel provided by the present application is also provided with an anti-reflux cap, which can block the return of blood from the false lumen of the dissection on the one hand, and on the other hand, the setting of the anti-reflux cap can increase the suture area with the autologous aortic wall, thereby increasing the anastomotic operation space and reducing the difficulty of anastomosis. The anti-reflux cap is used to anastomose with the aortic wall to avoid the compression of the aortic wall when the artificial blood vessel and the covered stent are directly sutured to the aortic wall, thereby avoiding long-term aortic wall necrosis and detachment, and improving the patient's quality of life after surgery. The design of the anti-reflux cap greatly simplifies the processing steps and processing time of the anastomosis between the integrated stent-type artificial blood vessel and the aortic arch, and can restore the systemic circulation as soon as possible by blocking the proximal end of the anti-reflux cap, thereby shortening the circulatory arrest time, enhancing the protection of brain tissue, reducing the risk of bleeding after anastomosis, shortening the overall operation time and extracorporeal circulation time, and facilitating the patient's postoperative recovery.

[0008] In some optional embodiments of the present application, the artificial brachiocephalic trunk branch, the artificial left carotid artery branch and the left subclavian artery branch are arranged on the same side of the main blood flow direction of the artificial blood vessel.

[0009] In some optional embodiments of the present application, in the main blood flow direction of the artificial blood vessel, the anti-reflux cap is located between the artificial left carotid artery branch and the left subclavian artery branch.

[0010] In some optional embodiments of the present application, the artificial blood vessel portion further includes:

[0011] The perfusion branch is arranged beside the main branch of the artificial blood vessel and is connected with the main branch of the artificial blood vessel. The perfusion branch and the artificial brachiocephalic trunk branch are arranged on the opposite side of the main blood flow direction of the artificial blood vessel.

[0012] In some optional embodiments of the present application, the diameter of the proximal portion of the main branch of the artificial blood vessel away from the coated stent gradually increases from the distal end of the artificial blood vessel portion to the proximal end of the artificial blood vessel portion.

[0013] In some optional embodiments of the present application, the trunk of the stent graft is cone-like in shape, and the diameter of the trunk of the stent graft gradually decreases from the proximal end of the stent graft to the distal end of the stent graft.

[0014] In some optional embodiments of the present application, the integrated stent-type artificial blood vessel further includes:

[0015] A reducing connection portion is arranged between the main branch of the artificial blood vessel and the main branch of the coated stent. The proximal end of the reducing connection portion is connected to the distal end of the main branch of the artificial blood vessel to form a first connection, and the radial size of the first connection matches. The distal end of the reducing connection portion is connected to the proximal end of the main branch of the coated stent to form a second connection, and the radial size of the second connection matches. The radial size of the second connection is greater than the radial size of the first connection.

[0016] In some optional embodiments of the present application, at least one step is formed on the axial outer peripheral wall of the variable diameter connection portion in the main blood flow direction of the artificial blood vessel.

[0017] In some optional embodiments of the present application,

[0018] The anti-reflux cap is cylindrical; or,

[0019] The anti-reflux cap is in the shape of a truncated cone, and the diameter of the bottom end of the anti-reflux cap close to the coated stent is larger than the diameter of the top end of the anti-reflux cap close to the artificial blood vessel.

[0020] The anti-reflux cap is made of the same material as the artificial blood vessel.

[0021] In some optional embodiments of the present application, the diameter of the bottom end of the anti-reflux cap close to the coated stent is larger than the proximal diameter of the main trunk of the coated stent. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is a schematic diagram of the same type of aortic dissection;

[0023] Figure 2 This is a schematic diagram of the anatomical structure of the human aorta;

[0024] Figure 3 This is a schematic diagram of the structure of an integrated stent-type artificial blood vessel provided in one embodiment of the present application;

[0025] Figure 4 This is a simplified structural diagram of the integrated stent-type artificial blood vessel structure provided in one embodiment of the present application after being implanted into the human body.

[0026] Description of reference numerals:

[0027] Artificial blood vessel part-1; artificial blood vessel main branch-11; distal end of the artificial blood vessel main branch-111; proximal end-112; artificial brachiocephalic trunk branch-12; artificial left carotid artery branch-13; perfusion branch-14;

[0028] Covered stent-2; Covered stent trunk-21; Left subclavian artery branch trunk-22;

[0029] Anti-reflux cap-3; top end-31; bottom end-32;

[0030] Reducer-4; Step-41;

[0031] The main blood flow direction of the artificial blood vessel is X. DETAILED DESCRIPTION

[0032] The following will be combined with the attached Figure 1 To Attachment Figure 4 The technical solution of this application is described in detail.

[0033] Figure 1 This is a schematic diagram of the same type of aortic dissection. The annual incidence of aortic dissection is 7.9 / 100,000 person-years to 16 / 100,000 person-years. According to the location of the rupture, it can be divided into Stanford type A and type B. The incidence of Stanford type A aortic dissection (TAAD) is about twice that of Stanford type B aortic dissection (TBAD). If not treated in time, the 24-hour mortality rate is as high as 50%. For TAAD, current guidelines recommend early open surgery to repair the torn aorta. However, open surgery often requires a midline thoracotomy and deep hypothermic circulatory arrest. Currently, traditional surgery for type A aortic dissection requires the freeing of autologous brachiocephalic branches, left common carotid artery, and left subclavian artery (i.e., the above three need to be cut off and then sutured with the implanted artificial blood vessels). Under circulatory arrest, the intraoperative covered stent is placed into the true lumen of the descending aorta. The covered stent and the four-branch artificial blood vessel (including the main branch of the artificial blood vessel, the artificial brachiocephalic branch, the artificial left carotid artery branch, and the artificial perfusion branch) are set separately. Therefore, the proximal end of the covered stent needs to be sutured with the distal end of the four-branch artificial blood vessel and the autologous aortic wall. Exposure is difficult, and there is interference from backflow during suturing. In addition, the free suture space is limited, which increases the difficulty of anastomosis, thereby prolonging the circulatory arrest time and affecting the protection of brain tissue. In addition, difficult surgical operations can easily lead to the risk of bleeding after anastomosis, prolonging the overall operation time, increasing the extracorporeal circulation time, and being unfavorable for postoperative recovery.

[0034] Figure 2 This is a schematic diagram of the anatomical structure of the human aorta. Figure 2 It can be seen that the aorta is mainly arch-shaped, and the aorta includes the ascending aorta and the descending aorta, the innominate artery (connected to the right subclavian artery and the right common carotid artery, the innominate artery can also be called a branch of the autologous brachiocephalic trunk), the left common carotid artery and the left subclavian artery formed on the greater curvature of the aortic arch.

[0035] like Figure 3 and Figure 4 As shown, the present application provides an integrated stent-type artificial blood vessel, comprising:

[0036] The artificial blood vessel part 1 comprises an artificial blood vessel main branch 11, an artificial brachiocephalic trunk branch 12 and an artificial left carotid artery branch 13 which are arranged beside the artificial blood vessel main branch 11 and communicated with the artificial blood vessel main branch 11;

[0037] A stent graft 2 connected to the distal end of the artificial blood vessel portion 1, the stent graft 2 comprising a stent graft trunk 21 and a left subclavian artery branch 22 disposed beside the stent graft trunk 21 and communicating with the stent graft trunk 21;

[0038] The anti-reflux cap 3 is arranged near the connection between the artificial blood vessel part 1 and the coated stent 2. The anti-reflux cap 3 is arranged around the outer periphery of the distal end 111 of the main branch of the artificial blood vessel, and the cap opening of the anti-reflux cap 3 faces the coated stent 2.

[0039] The integrated stent-type artificial blood vessel provided in the embodiment of the present application has an integrated design in which the artificial blood vessel part 1 is connected to the coated stent 2, thereby avoiding the problem of difficult exposure caused by the need to suture the proximal end of the coated stent 2 with the distal end of the four-branch artificial blood vessel and the native aorta wall. There is no need to anastomose the stent and the artificial blood vessel during surgery, which reduces the anastomosis time and avoids the risk of bleeding at the anastomosis site. The coated stent 2 includes a left subclavian artery branch trunk 22, which can be opened in the area between the native left common carotid artery and the native left subclavian artery after the native aorta is cut open (please refer to the detailed instructions for details). Figure 2 The black dotted line in the middle), the left subclavian artery branch trunk 22 is inserted into the autologous left subclavian artery, which avoids the freedom of the autologous left subclavian artery during the operation and avoids the anastomosis of a branch of the artificial blood vessel with the autologous left subclavian artery, reducing operations and reducing operation time. The integrated stent-type artificial blood vessel provided in the present application is also provided with an anti-reflux cap 3, which can block the return of blood from the false lumen of the dissection on the one hand, and on the other hand, the setting of the anti-reflux cap 3 can increase the suture area with the autologous aortic wall, thereby increasing the anastomosis operation space and reducing the difficulty of anastomosis. The anti-reflux cap 3 is used to anastomose with the aortic wall to avoid the compression of the aortic wall when the artificial blood vessel and the covered stent 2 are directly sutured to the aortic wall, thereby avoiding long-term aortic wall necrosis and detachment, and improving the patient's quality of life after surgery. The design of the anti-reflux cap 3 greatly simplifies the processing steps and processing time of the integrated stent-type artificial blood vessel and the aortic arch anastomosis, which can restore the systemic circulation as soon as possible after the proximal blockade of the anti-reflux cap 3, thereby shortening the circulatory arrest time, enhancing the protection of brain tissue, reducing the risk of post-anastomosis bleeding, shortening the overall operation time and extracorporeal circulation time, and facilitating the patient's postoperative recovery.

[0040] It should be noted that in the present application, the proximal end and the distal end are divided according to the main blood flow direction X of the artificial blood vessel. In the present application, the proximal end of a tubular structure (for example, the artificial blood vessel main branch 11, the coated stent main branch 21) is the blood inlet end, and the distal end of the tubular structure is the blood outlet end. The proximal end of an integral structure (for example, the artificial blood vessel part 1, the coated stent 2) is the blood inlet end of the integral structure (the proximal end of the artificial blood vessel part 1 is the same as the proximal end of the artificial blood vessel main branch 11, and the proximal end of the coated stent 2 is the same as the proximal end of the coated stent main trunk 21), and the distal end is the blood outflow end of the integral structure (the distal end of the artificial blood vessel part 1 is the same as the distal end of the artificial blood vessel main branch 11, and the distal end of the coated stent 2 is the same as the distal end of the coated stent main trunk 21).

[0041] In some optional embodiments of the present application, the artificial brachiocephalic trunk branch 12, the artificial left carotid artery branch 13, and the left subclavian artery branch 22 are arranged on the same side of the main blood flow direction X of the artificial blood vessel. In these embodiments, the artificial brachiocephalic trunk branch 12, the artificial left carotid artery branch 13, and the left subclavian artery branch 22 are arranged on the same side of the main blood flow direction X of the artificial blood vessel in order to conform to the structure of the human aorta.

[0042] In some optional embodiments of the present application, in the main blood flow direction X of the artificial blood vessel, the anti-reflux cap 3 is located between the artificial left carotid artery branch 13 and the left subclavian artery branch trunk 22. In these embodiments, during the operation of implanting an integrated stent-type artificial blood vessel, the anti-reflux cap 3 is sutured with the patient's autologous aortic wall in front of the left subclavian artery near the proximal end of the coated stent trunk 21, which can effectively prevent the return of blood from the partial dissection false cavity formed in the aortic arch or the proximal descending aorta. The setting of the anti-reflux cap 3 can increase the suture area with the autologous aortic wall, increase the anastomosis operation space, and reduce the difficulty of anastomosis.

[0043] In some optional embodiments of the present application, the artificial blood vessel part 1 further includes:

[0044] The perfusion branch 14 is arranged beside the main branch 11 of the artificial blood vessel and is connected with the main branch 11 of the artificial blood vessel. The perfusion branch 14 and the artificial brachiocephalic trunk branch 12 are arranged on the opposite side of the main blood flow direction X of the artificial blood vessel.

[0045] In these embodiments, the perfusion branch 14 is mainly used to provide physiological cerebral blood flow during circulatory arrest during surgery to protect the brain. It can provide sufficient oxygen and nutrients during longer circulatory arrest, increase the operation time of aortic arch surgery, reduce postoperative complications, and provide better brain protection.

[0046] In some optional embodiments of the present application, the diameter of the proximal portion 112 of the artificial blood vessel main branch 11 away from the coated stent 2 gradually increases from the distal end of the artificial blood vessel portion 1 to the proximal end of the artificial blood vessel portion 1 .

[0047] In these embodiments, the diameter of the proximal portion 112 of the artificial blood vessel main branch 11 is changed to match the diameter of the ascending aorta, which facilitates the anastomosis operation between the artificial blood vessel portion 1 and the ascending aorta during surgery.

[0048] In some optional embodiments of the present application, the stent graft trunk 21 is cone-shaped, and the diameter of the stent graft trunk 21 gradually decreases from the proximal end of the stent graft 2 to the distal end of the stent graft 2 .

[0049] In these embodiments, the coated stent trunk 21 is configured in a quasi-conical shape, and the proximal diameter of the coated stent trunk 21 is larger than the distal diameter of the coated stent trunk 21, conforming to the structure of the human aorta. The proximal end of the coated stent trunk 21 is more in line with the aorta diameter and fits well with the aortic wall, reducing false lumen reflux.

[0050] Figure 3 The structure indicated by the thick black arrow in the middle is a schematic diagram of the structure of the variable diameter connection part 4 provided between the main branch 11 of the artificial blood vessel and the main branch 21 of the covered stent after the anti-reflux cap 3 is hidden.

[0051] In some optional embodiments, the integrated stent-type artificial blood vessel further includes:

[0052] The reducing connection part 4 is arranged between the main branch of the artificial blood vessel 11 and the main branch of the coated stent 21. The proximal end of the reducing connection part 4 is connected to the distal end of the main branch of the artificial blood vessel 11 to form a first connection, and the radial size of the first connection matches. The distal end of the reducing connection part 4 is connected to the proximal end of the main branch of the coated stent 21 to form a second connection, and the radial size of the second connection matches. The radial size of the second connection is greater than the radial size of the first connection.

[0053] In some optional embodiments, in the main blood flow direction X of the artificial blood vessel, at least one step 41 is formed on the axial outer peripheral wall of the variable diameter connection part 4.

[0054] The reducing connection part 4 is provided with a step 41 to ensure that the artificial blood vessel main branch 11 meets the requirements of matching with the valve ring or the junction of the sinus tube. The artificial blood vessel main branch 11 has a smaller diameter, and avoids the inability to match a suitable stent at the distal end of the aortic arch to limit the false lumen reflux of the artificial blood vessel main branch 11.

[0055] The transition step 41 from the main stent to the artificial blood vessel: This design avoids limiting the selection of the stent diameter due to the requirement of the proximal artificial blood vessel diameter, so that a suitable stent cannot be matched at the distal end of the aortic arch to limit the false lumen regurgitation. This design can select an artificial blood vessel with a suitable diameter at the proximal end and does not limit the selection of the diameter of the main covered stent 2, thereby better avoiding the false lumen regurgitation.

[0056] The artificial blood vessel main branch 11 is relatively small, ensuring that the artificial blood vessel main branch 11 meets the requirements of matching the valve ring or the sinus tube junction, while the proximal diameter of the covered stent main branch 21 needs to be increased to limit the false lumen reflux. The step 41 provided on the reducer 4 well meets the different requirements of the proximal diameter of the reducer 4 and the distal diameter of the reducer 4; according to the principle that the flow velocity slows down as the cross-sectional area of ​​the flowing blood increases and the principle of blocking the false lumen reflux, the step 41 can play a role in limiting and slowing the false lumen reflux.

[0057] After the step 41 of the reducer 4 is provided to restrict the false lumen reflux for the first time, if there is still false lumen return blood that slows down the flow into the anti-reflux cap 3, more comprehensive anti-reflux can be achieved through the anti-reflux cap 3. The reducer 4 and the anti-reflux cap 3 form two barriers against false lumen reflux.

[0058] In some optional embodiments of the present application, the anti-reflux cap 3 and the artificial blood vessel part 1 are made of the same material. In some embodiments, the anti-reflux cap 3 and the artificial blood vessel part 1 are made of polyester woven material.

[0059] In some optional embodiments, the coated stent 2 includes a stent body made of a shape memory material and a coating material coated on the stent body. The coating material can be polytetrafluoroethylene with excellent elastic properties.

[0060] In some optional embodiments of the present application, the anti-reflux cap 3 is cylindrical.

[0061] In some optional embodiments of the present application, the anti-reflux cap 3 is in a truncated cone shape, and the diameter of the bottom end 32 of the anti-reflux cap 3 close to the coated stent 2 is larger than the diameter of the top end 31 of the anti-reflux cap 3 close to the artificial blood vessel part 1.

[0062] In some optional embodiments of the present application, the diameter of the bottom end 32 of the anti-reflux cap 3 close to the coated stent 2 is larger than the proximal diameter of the coated stent trunk 21 .

[0063] Please refer to Figures 2 to 4 As shown, in some examples, when the integrated stent-type artificial blood vessel provided by the embodiment of the present application is implanted in the human body, the autologous innominate artery and the autologous left common carotid artery are cut off, and the autologous aorta is cut open between the autologous left common carotid artery and the autologous left subclavian artery (for details, please refer to Figure 2 The left subclavian artery branch trunk 22 is inserted into the autologous left subclavian artery to avoid the autologous left subclavian artery from being freed during the operation and to avoid the anastomosis of a branch of the artificial blood vessel with the autologous left subclavian artery, thereby reducing the number of operations and the operation time.

[0064] The bottom end 32 of the anti-reflux cap 3 is sutured with the arterial wall of the native aorta near the native left subclavian artery. The setting of the anti-reflux cap 3 can increase the suture area with the native aortic wall, thereby increasing the anastomosis operation space and reducing the difficulty of anastomosis. The anti-reflux cap 3 is used to anastomose with the aortic wall to avoid the compression of the aortic wall when the artificial blood vessel and the coated stent 2 are directly sutured to the aortic wall, thereby avoiding long-term aortic wall necrosis and detachment, and improving the patient's postoperative quality of life. The setting of the anti-reflux cap 3 also increases the boundary for wrapping the aorta and shunting.

[0065] The integrated stent-type artificial blood vessel provided in the present application is also provided with an anti-reflux cap 3, which can block the return of blood from the false lumen of the dissection on the one hand, and on the other hand, the provision of the anti-reflux cap 3 can increase the suture area with the native aortic wall, thereby increasing the anastomotic operation space and reducing the difficulty of anastomosis. The anti-reflux cap 3 is used to anastomose with the aortic wall to avoid the compression of the aortic wall when the artificial blood vessel and the covered stent 2 are directly sutured with the aortic wall, thereby avoiding long-term necrosis and detachment of the aortic wall and improving the patient's quality of life after surgery. The design of the anti-reflux cap 3 greatly simplifies the processing steps and processing time of the anastomosis between the integrated stent-type artificial blood vessel and the aortic arch, and can make the proximal blockage of the anti-reflux cap 3 restore the systemic circulation as soon as possible, thereby shortening the circulatory arrest time, enhancing the protection of brain tissue, reducing the risk of bleeding after anastomosis, shortening the overall operation time and extracorporeal circulation time, and facilitating the patient's postoperative recovery.

[0066] The artificial brachiocephalic trunk branch 12 of the artificial blood vessel is sutured and connected to the autologous innominate artery, the artificial left carotid artery branch 13 is sutured and connected to the autologous left common carotid artery, and the proximal end of the main branch 11 of the artificial blood vessel is matched with the valve ring or the junction of the sinus tube.

[0067] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited thereto. Any changes or substitutions that can be easily thought of by a person skilled in the art within the technical scope disclosed in the present application should be included in the protection scope of the present application. Therefore, the protection scope of the present application shall be based on the protection scope of the claims.

Claims

1. An integrated stent-type artificial blood vessel, characterized in that: include: The artificial blood vessel part includes an artificial blood vessel main branch, an artificial brachiocephalic trunk branch and an artificial left carotid artery branch which are arranged beside the artificial blood vessel main branch and communicated with the artificial blood vessel main branch; A covered stent connected to the distal end of the artificial blood vessel portion, the covered stent comprising a covered stent trunk and a left subclavian artery branch disposed beside the covered stent trunk and connected to the covered stent trunk; An anti-reflux cap is arranged near the connection between the artificial blood vessel part and the coated stent. The anti-reflux cap is arranged around the outer periphery of the distal end of the main branch of the artificial blood vessel, and the cap opening of the anti-reflux cap faces the coated stent.

2. The integrated stent-type artificial blood vessel according to claim 1, characterized in that: The artificial brachiocephalic trunk branch, the artificial left carotid artery branch and the left subclavian artery branch are arranged on the same side in the main blood flow direction of the artificial blood vessel.

3. The integrated stent-type artificial blood vessel according to claim 2, characterized in that: In the main blood flow direction of the artificial blood vessel, the anti-reflux cap is located between the artificial left carotid artery branch and the left subclavian artery branch.

4. The integrated stent-type artificial blood vessel according to claim 2, characterized in that: The artificial blood vessel portion further comprises: The perfusion branch is arranged beside the main branch of the artificial blood vessel and is connected with the main branch of the artificial blood vessel. The perfusion branch and the artificial brachiocephalic trunk branch are arranged on the opposite side of the main blood flow direction of the artificial blood vessel.

5. The integrated stent-type artificial blood vessel according to any one of claims 1 to 4, characterized in that: The diameter of the proximal portion of the main branch of the artificial blood vessel away from the stent graft gradually increases from the distal end of the artificial blood vessel portion to the proximal end of the artificial blood vessel portion.

6. The integrated stent-type artificial blood vessel according to claim 1, characterized in that: The main trunk of the stent graft is in a cone-like shape, and the diameter of the main trunk of the stent graft gradually decreases from the proximal end of the stent graft to the distal end of the stent graft.

7. The integrated stent-type artificial blood vessel according to claim 6, characterized in that: The integrated stent-type artificial blood vessel also includes: A reducing connection portion is arranged between the main branch of the artificial blood vessel and the main branch of the coated stent. The proximal end of the reducing connection portion is connected to the distal end of the main branch of the artificial blood vessel to form a first connection, and the radial size of the first connection matches. The distal end of the reducing connection portion is connected to the proximal end of the main branch of the coated stent to form a second connection, and the radial size of the second connection matches. The radial size of the second connection is greater than the radial size of the first connection.

8. The integrated stent-type artificial blood vessel according to claim 7, characterized in that: In the main blood flow direction of the artificial blood vessel, the axial outer peripheral wall of the variable diameter connection part is formed with at least one step.

9. The integrated stent-type artificial blood vessel according to claim 1, characterized in that: The anti-reflux cap is cylindrical; or, The anti-reflux cap is in a truncated cone shape, and the diameter of the bottom end of the anti-reflux cap close to the coated stent is larger than the diameter of the top end of the anti-reflux cap close to the artificial blood vessel.

10. The integrated stent-type artificial blood vessel according to claim 8 or 9, characterized in that: The diameter of the bottom end of the anti-reflux cap close to the coated stent is larger than the proximal diameter of the main trunk of the coated stent.

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