Explosion-proof tube type plasma protein filtering device

Abstract

The utility model provides an anti-explosion tubular plasma protein filtering device which comprises a workbench, a liquid storage device, a liquid guide device and a filtering device, the working table comprises an upper table top and a lower table top, a liquid storage device and a liquid guide device are placed on the upper table top, and a filtering device is placed on the lower table top; the liquid storage device comprises a liquid storage bottle, a first rack and a supporting mechanism, the liquid storage bottle is placed on the first rack, the first rack supports the bottom of the liquid storage bottle, the supporting mechanism is arranged at the end, close to the liquid guide device, of the first rack, and the liquid guide device is fixed to the upper table top and located between the liquid storage device and the filtering device. And an anti-falling mechanism is arranged at the joint of the conveying pipe and the filtering device. By means of the anti-falling mechanism between the conveying pipe and the upper cover, the conveying pipe and the filter are prevented from falling off, and plasma leakage is avoided.

Description

Technical Field

[0001] The utility model relates to a filtering device, in particular to an explosion-proof tubular plasma protein filtering device. Background Art

[0002] In the process of blood collection and storage, in order to prevent blood coagulation and corruption, a certain proportion of anticoagulants and preservatives are usually added to the blood, such as sodium citrate, sodium tripolyphosphate and EDTA disodium salt. Through centrifugation, blood can be divided into plasma (light yellow) and blood cells (red). These anticoagulants and preservatives are mainly retained in plasma. In order to produce low-salt, high-protein, high-quality and high-purity plasma products, the plasma needs to be desalted and concentrated before further processing.

[0003] According to patent number CN202111261053.5, a plasma filter is provided with at least one filter cartridge inside its filter body, and the filter body has an external liquid inlet and a liquid outlet, the external liquid inlet is used to connect and communicate with the plasma delivery tube, and the plasma entering the filter body through the external liquid inlet can flow into the filter cartridge, and the filter cartridge is used to filter out the fibrinogen in the plasma. When the plasma flows into the filter through the liquid inlet, the air pressure in the filter will continue to increase, thereby pressing the delivery tube out of the filter inlet, causing the plasma to be unable to be filtered. Utility Model Content

[0004] The utility model provides an explosion-proof tubular plasma protein filtering device, which solves the problem in the prior art that plasma continuously flows into the filter, increasing the internal air pressure of the filter and causing the delivery tube to be pressed out of the filter.

[0005] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme: the utility model provides an explosion-proof tubular plasma protein filtering device, comprising: a workbench, a liquid storage device, a liquid guiding device and a filtering device; the workbench is an L-shaped structure, and the workbench comprises: an upper table and a lower table, the upper table is provided with a liquid storage device and a liquid guiding device, and the lower table is provided with a filtering device; the liquid storage device comprises: a liquid storage bottle, a first stand and a supporting mechanism, the liquid storage bottle is placed on the first stand, the first stand supports the bottom of the liquid storage bottle, the first stand is provided with a supporting mechanism near one end of the liquid guiding device, and the supporting mechanism supports the middle part of the liquid storage bottle; the liquid guiding device is fixed on the upper table and is located between the liquid storage device and the filtering device, the liquid guiding device comprises: a peristaltic pump and a delivery pipe, the delivery pipe passes through the peristaltic pump, one end of the delivery pipe is connected to the liquid storage bottle, the other end of the delivery pipe is connected to the filtering device, and an anti-slip mechanism is provided at the connection between the delivery pipe and the filtering device;

[0006] The filtering device includes: a second frame and a filter. The second frame is fixed on the lower table, the filter is installed on one side of the upper end of the second frame, the delivery pipe extends into the filter, and an anti-detachment mechanism is provided at the connection between the filter and the delivery pipe. The anti-detachment mechanism is used to prevent the delivery pipe from detaching from the filter.

[0007] Preferably, the filter comprises: an upper cover, a filter part and a liquid outlet part, a liquid inlet is opened at the top of the upper cover, the delivery pipe passes through the liquid inlet and extends into the filter, the upper cover is spirally installed on the top of the filter part, and the bottom of the filter part is connected to the liquid outlet part.

[0008] Preferably, the anti-slip mechanism is a snap mechanism, which includes: a first snap and a second snap, the first snap is installed on the side wall of one end of the conveying tube connected to the upper cover, and the second snap is installed on the top of the upper cover close to the first snap, and the first snap is snap-fitted with the second snap.

[0009] Preferably, the first buckle and the second buckle both have a supporting surface, a hook surface and a sliding extrusion surface, the direction in which the delivery tube is inserted into the upper cover is the X direction, the supporting surface is parallel to the X direction, the hook surface is perpendicular to the supporting surface, and the hook surface and the supporting surface are connected to form a hook groove, and a sliding extrusion surface is connected to the side of the hook surface facing away from the supporting surface, the first buckle and the second buckle are both elastic, and before the first buckle and the second buckle are buckled together, the sliding extrusion surface of the first buckle is used to elastically deform the first buckle and the second buckle by extruding the sliding extrusion surface of the second buckle.

[0010] Preferably, the anti-slip mechanism is a spiral fastening mechanism, and the spiral fastening mechanism includes: a nut and a hollow bolt, the hollow bolt is fixed on the upper cover, the delivery pipe can pass through the hollow bolt and extend into the upper cover, the nut is sleeved on the delivery pipe, and a ring baffle is provided at one end of the delivery pipe close to the hollow bolt, the nut can rotate relative to the delivery pipe, the ring baffle prevents the nut from sliding out of the delivery pipe, and the nut is threadedly connected to the hollow bolt.

[0011] Preferably, the supporting mechanism comprises: an upper supporting frame and a lower supporting frame, wherein two lower supporting frames are provided, the lower supporting frame is fixed to one end of the first frame close to the liquid guiding device, the lower supporting frame is provided with at least two positioning holes in the vertical direction, and the upper supporting frame and the lower supporting frame are positioned by means of a screw and a nut, and the screw passes through the positioning hole.

[0012] Preferably, the axis of the liquid storage bottle is at an angle of 75 degrees to the horizontal direction, and a groove for supporting storage is provided on the top of the upper support frame.

[0013] Preferably, the second stand includes: a support plate, the support plate is an L-shaped structure, the first side of the support plate is fixedly connected to the lower table surface, a connecting surface is formed between the upper table surface and the lower table surface in the workbench, the second side of the support plate is in close contact with the connecting surface, the second side protrudes with a first support platform and a second support platform, the first support platform is provided with a first support ring with an inner diameter the same as the outer diameter of the filter part near one end of the filter, the first support ring is for the filter to pass through, and the first support ring is fixed to the outer wall of the filter, a second support ring is fixed on the second support, the second support ring is for the bottom end of the filter to pass through, and the second support ring supports the filter.

[0014] Compared with the prior art, the utility model has the following beneficial effects: the explosion-proof tube-type plasma protein filtering device adopts a liquid storage bottle to store plasma on the first stand, the bottom of the liquid storage bottle is connected to a delivery tube, and the plasma is delivered to the filter by squeezing the delivery tube by a peristaltic pump, and an anti-slip mechanism is provided at the connection between the delivery tube and the upper cover, which is implemented by means of snap locking and thread fixing, so that when the delivery tube is inserted into the filter during the test, it is prevented from being squeezed out of the upper cover by the air pressure in the filter, and then the delivery tube is prevented from being discharged and causing liquid leakage, that is, the tube explosion phenomenon in the test is avoided, the progress of the entire test is avoided, and the entire test environment is also avoided from being affected by liquid leakage. A support frame is provided on the first frame, and a positioning hole is opened on the lower support frame. The relative positions of the upper support frame and the lower support frame can be adjusted by inserting bolts into different positioning holes. When the liquid storage bottle is against the upper support frame, the inclination angle of the liquid storage bottle can be adjusted so that the liquid in the liquid storage bottle can be fully discharged from the bottom, avoiding the liquid staying in the liquid storage bottle and affecting the amount of liquid added in the test, ensuring that the test can be carried out in an orderly manner, and the groove on the upper support frame increases the stability of the placement of the liquid storage bottle; a first support platform and a second support platform are provided on the second frame, which can support the filter and keep the filter in a vertical state, solving the problem of lack of stability of the filter when in use by hand, making the filter more convenient to use.

[0015] Other advantages, objectives and features of the present invention will be embodied in part through the following description, and in part will be understood by those skilled in the art through research and practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of an explosion-proof tubular plasma protein filtration device.

[0017] Figure 2 This is a partial schematic diagram of an explosion-proof tubular plasma protein filtration device.

[0018] Figure 3 This is a schematic diagram of the anti-shedding mechanism of the explosion-proof tubular plasma protein filtration device.

[0019] Figure 4This is a partial schematic diagram of an explosion-proof tubular plasma protein filtration device.

[0020] Figure 5 This is a schematic diagram of the anti-shedding mechanism of the explosion-proof tubular plasma protein filtration device.

[0021] Figure 6 It is a cross-sectional view of the anti-fall-off mechanism of the explosion-proof tubular plasma protein filter device.

[0022] : Figure numerals: workbench 1, upper table 11, lower table 12, connecting surface 13, liquid storage device 2, liquid storage bottle 21, first stand 22, supporting mechanism 23, upper supporting frame 231, groove 2311, lower supporting frame 232, positioning hole 2321, screw 2322, liquid guiding device 3, peristaltic pump 31, delivery tube 32, anti-slip mechanism 33, snap mechanism 34, first snap 341, supporting surface 3411, hook surface 3412, sliding extrusion surface 3413, second snap 342, spiral fastening mechanism 35, nut 351, hollow bolt 352, ring baffle 353, filtering device 4, second stand 41, first supporting platform 411, first supporting ring 4111, second supporting platform 412, second supporting ring 4121, filter 42, upper cover 421, filtering part 422, liquid outlet part 423. DETAILED DESCRIPTION

[0023] In order to make the technical means, creative features, objectives and functions of the present invention clearer and easier to understand, the present invention is further described below in conjunction with the accompanying drawings and specific implementation methods:

[0024] Example 1

[0025] like Figures 1 to 4As shown, the utility model proposes an explosion-proof tubular plasma protein filtering device 4, comprising: a workbench 1, a liquid storage device 2, a liquid guiding device 3 and a filtering device 4; the workbench 1 is an L-shaped structure, and the workbench 1 comprises: an upper table 11 and a lower table 12, the upper table 11 is provided with the liquid storage device 2 and the liquid guiding device 3, and the filtering device 4 is placed on the lower table 12; the liquid storage device 2 comprises: a liquid storage bottle 21, a first stand 22 and a supporting mechanism 23, the liquid storage bottle 21 is placed on the first stand 22, the first stand 22 supports the bottom of the liquid storage bottle 21, and the first stand 22 is provided with a supporting mechanism at one end close to the liquid guiding device 3 Mechanism 23, the supporting mechanism 23 supports the middle part of the liquid storage bottle 21; the liquid guiding device 3 is fixed on the upper table 11 and is located between the liquid storage device 2 and the filtering device 4, the liquid guiding device 3 includes: a peristaltic pump 31 and a delivery tube 32, the delivery tube 32 passes through the peristaltic pump 31, one end of the delivery tube 32 is connected to the liquid storage bottle 21, and the other end of the delivery tube 32 is connected to the filtering device 4, and an anti-slip mechanism 33 is provided at the connection between the delivery tube 32 and the filtering device 4; the liquid storage bottle 21 stores plasma on the first stand 22, the delivery tube 32 guides the plasma from the liquid storage bottle 21, and transports the plasma to the filtering device 4 for filtration through the vibration pump.

[0026] The filtering device 4 includes: a second frame 41 and a filter 42. The second frame 41 is fixed on the lower table 12. The filter 42 is installed on one side of the upper end of the second frame 41. The delivery tube 32 extends into the filter 42, and an anti-detachment mechanism 33 is provided at the connection between the filter 42 and the delivery tube 32. The anti-detachment mechanism 33 is used to prevent the delivery tube 32 from being separated from the filter 42. When plasma is continuously delivered to the filter 42, the air pressure inside the filter 42 continues to increase. The internal air pressure can easily push the delivery tube 32 inserted into the filter 42 out of the filter 42. The anti-detachment mechanism 33 can prevent the delivery tube 32 from being squeezed out of the filter 42 by the air pressure.

[0027] The filter 42 includes: an upper cover 421, a filter portion 422 and a liquid outlet portion 423. A liquid inlet is opened at the top of the upper cover 421, and the delivery pipe 32 extends into the filter 42 through the liquid inlet. The upper cover 421 is buckled on the top of the filter portion 422, and the bottom of the filter portion 422 is connected to the liquid outlet portion 423.

[0028] The anti-slip mechanism 33 is a snap mechanism 34, which includes: a first snap 341 and a second snap 342. The first snap 341 is installed on the side wall of the delivery tube 32 connected to one end of the upper cover 421, and the second snap 342 is installed on the top of the upper cover 421 close to the first snap 341. The first snap 341 and the second snap 342 are snap-fitted.

[0029] The first buckle 341 and the second buckle 342 both have a supporting surface 3411, a hook surface 3412 and a sliding extrusion surface 3413. The direction in which the conveying tube 32 is inserted into the upper cover 421 is the X direction. The supporting surface 3411 is parallel to the X direction, the hook surface 3412 is perpendicular to the supporting surface 3411, and the hook surface 3412 is connected to the supporting surface 3411 to form a hook groove, and the sliding extrusion surface 3413 is connected to the side of the hook surface 3412 that is away from the supporting surface 3411. The first buckle 341 and the second buckle 342 are both elastic. Before the first buckle 341 and the second buckle 342 are buckled together, the sliding extrusion surface 3413 of the first buckle 341 is used to elastically deform the first buckle 341 and the second buckle 342 by extruding the sliding extrusion surface 3413 of the second buckle 342. When the delivery tube 32 is inserted into the upper cover 421, the sliding extrusion surface 3413 of the first buckle 341 and the sliding extrusion surface 3413 of the second buckle 342 are squeezed against each other, thereby causing the first buckle 341 and the second buckle 342 to undergo a certain deformation, so that the first buckle 341 jumps over the second buckle 342, and finally when reaching the hook groove position, the first buckle 341 and the second buckle 342 are engaged with each other, so that the delivery tube 32 can be locked after being inserted into the upper cover 421 and prevented from slipping out.

[0030] The support mechanism 23 includes: an upper support frame 231 and a lower support frame 232. Two lower support frames 232 are provided. The lower support frame 232 is fixed to one end of the first stand 22 close to the liquid guiding device 3. The lower support frame 232 is provided with at least two positioning holes 2321 in the vertical direction. The upper support frame 231 and the lower support frame 232 are positioned by screws 2322 and nuts, and the screws 2322 pass through the positioning holes 2321. When the screws 2322 pass through different positioning holes 2321, the height of the upper support frame 231 can be adjusted. When the liquid storage bottle 21 leans against the upper support frame 231, the tilt angle of the liquid storage bottle 21 can be adjusted.

[0031] The axis of the liquid storage bottle 21 is at an angle of 75 degrees to the horizontal direction. A groove 2311 for supporting storage is provided on the top of the upper support frame 231 . The groove 2311 can increase the stability of the liquid storage bottle 21 leaning against the upper support frame 231 .

[0032] The second stand 41 includes: a support plate, which is an L-shaped structure, the first side of the support plate is fixedly connected to the lower table 12, a connection surface 13 is formed between the upper table 11 and the lower table 12 in the workbench 1, the second side of the support plate is in close contact with the connection surface 13, and the second side is protruded with a first support platform 411 and a second support platform 412, and the first support platform 411 is provided with a first support ring 4111 with an inner diameter equal to the outer diameter of the filter part 422 at one end close to the filter 42, the first support ring 4111 is for the filter 42 to pass through, and the first support ring 4111 is fixed to the outer wall of the filter 42, and a second support ring 4121 is fixed on the second support, the second support ring 4121 is for the bottom end of the filter 42 to pass through, and the second support ring 4121 supports the filter 42. The second stand 41 can stably support the filtering device 4, and the first support ring 4111 and the second support ring 4121 keep the filtering bottle in a vertical direction, so that the plasma flows to the filtering bottle for filtering treatment.

[0033] This anti-slip mechanism 33 between the delivery tube 32 and the upper cover 421 is the best. First, the first buckle 341 and the second buckle 342 are located outside the delivery tube 32 and the upper cover 421, which can prevent liquid from contaminating the first buckle 341 and the second buckle 342. Second, it can prevent the delivery tube 32 from being detached from the upper cover 421. Third, when the delivery tube 32 is inserted into the filter 42, the first buckle 341 and the second buckle 342 can be snap-fitted, and no other operations are required. The operation is convenient and simple, which can improve the test efficiency. This is the biggest difference from Example 2. Example 2 requires rotation positioning, and the operation is more complicated.

[0034] Example 2

[0035] like Figures 5 and 6 As shown, compared with Example 1, this embodiment is different only in the anti-slip mechanism 33, and the other structures are the same as those of the embodiment.

[0036] In this embodiment, the anti-slip mechanism 33 is a spiral fastening mechanism 35, which includes a nut 351 and a hollow bolt 352. The hollow bolt 352 is fixed on the upper cover 421, and the delivery pipe 32 can pass through the hollow bolt 352 and extend into the upper cover 421. The nut 351 is sleeved on the delivery pipe 32. The delivery pipe 32 is provided with a ring baffle 353 at one end close to the hollow bolt 352. The nut 351 can rotate relative to the delivery pipe 32. The ring baffle 353 prevents the nut 351 from sliding out of the delivery pipe 32. The nut 351 is threadedly connected with the hollow bolt 352. After the delivery pipe 32 is inserted into the upper cover 421, the nut 351 is used to contact the hollow bolt 352 downward and tighten through the thread. When the delivery pipe 32 is discharged, the ring baffle 353 at the end of the delivery pipe 32 can prevent the nut 351 from being separated from the delivery pipe 32.

[0037] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model rather than to limit it. Although the utility model has been described in detail with reference to the preferred embodiments, ordinary technicians in the field should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the purpose and scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.

Claims

1. An explosion-proof tubular plasma protein filter, characterized in that: include: A workbench (1), a liquid storage device (2), a liquid guiding device (3) and a filtering device (4); The workbench (1) is an L-shaped structure, and comprises an upper table (11) and a lower table (12), wherein the upper table (11) is provided with a liquid storage device (2) and a liquid guide device (3), and the lower table (12) is provided with a filter device (4); The liquid storage device (2) comprises: a liquid storage bottle (21), a first stand (22) and a support mechanism (23); the liquid storage bottle (21) is placed on the first stand (22); the first stand (22) supports the bottom of the liquid storage bottle (21); a support mechanism (23) is provided at one end of the first stand (22) close to the liquid guiding device (3); and the support mechanism (23) supports the middle of the liquid storage bottle (21); The liquid guiding device (3) is fixed on the upper table (11) and is located between the liquid storage device (2) and the filtering device (4). The liquid guiding device (3) comprises: a peristaltic pump (31) and a delivery pipe (32). The delivery pipe (32) passes through the peristaltic pump (31). One end of the delivery pipe (32) is connected to the liquid storage bottle (21). The other end of the delivery pipe (32) is connected to the filtering device (4). An anti-slip mechanism (33) is provided at the connection between the delivery pipe (32) and the filtering device (4). The filtering device (4) comprises: a second frame (41) and a filter (42); the second frame (41) is fixed on the lower table (12); the filter (42) is installed on one side of the upper end of the second frame (41); the delivery pipe (32) extends into the filter (42); and an anti-slip mechanism (33) is provided at the connection between the filter (42) and the delivery pipe (32); the anti-slip mechanism (33) is used to prevent the delivery pipe (32) from being detached from the filter (42).

2. The explosion-proof tubular plasma protein filter device according to claim 1, characterized in that: The filter (42) comprises: an upper cover (421), a filter portion (422) and a liquid outlet portion (423). A liquid inlet is provided at the top of the upper cover (421), and a delivery pipe (32) passes through the liquid inlet and extends into the filter (42). The upper cover (421) is spirally mounted on the top of the filter portion (422), and the bottom of the filter portion (422) is connected to the liquid outlet portion (423).

3. The explosion-proof tubular plasma protein filter device according to claim 2, characterized in that: The anti-slip mechanism (33) is a snap mechanism (34), which comprises a first snap (341) and a second snap (342), wherein the first snap (341) is mounted on a side wall of the delivery tube (32) connected to one end of the upper cover (421), and the second snap (342) is mounted on a side of the top of the upper cover (421) close to the first snap (341), and the first snap (341) and the second snap (342) are snap-fitted.

4. The explosion-proof tubular plasma protein filter device according to claim 3, characterized in that: The first buckle (341) and the second buckle (342) both have a support surface (3411), a hook surface (3412) and a sliding extrusion surface (3413). The direction in which the delivery tube (32) is inserted into the upper cover (421) is the X direction. The support surface (3411) is parallel to the X direction. The hook surface (3412) is perpendicular to the support surface (3411). The hook surface (3412) is connected to the support surface (3411) to form a hook groove. A sliding extrusion surface (3413) is connected to the side away from the support surface (3411); the first buckle (341) and the second buckle (342) are both elastic; before the first buckle (341) and the second buckle (342) are snap-fitted, the sliding extrusion surface (3413) of the first buckle (341) is used to elastically deform the first buckle (341) and the second buckle (342) by extruding the sliding extrusion surface (3413) of the second buckle (342).

5. The explosion-proof tubular plasma protein filter device according to claim 2, characterized in that: The anti-slip mechanism (33) is a spiral fastening mechanism (35), which comprises: a nut (351) and a hollow bolt (352), wherein the hollow bolt (352) is fixed on the upper cover (421), the delivery pipe (32) can pass through the hollow bolt (352) and extend into the upper cover (421), the nut (351) is sleeved on the delivery pipe (32), an annular baffle (353) is provided at one end of the delivery pipe (32) close to the hollow bolt (352), the nut (351) can rotate relative to the delivery pipe (32), the annular baffle (353) prevents the nut (351) from sliding out of the delivery pipe (32), and the nut (351) is threadedly connected to the hollow bolt (352).

6. The explosion-proof tubular plasma protein filter device according to any one of claims 3 to 5, characterized in that: The support mechanism (23) comprises: an upper support frame (231) and a lower support frame (232), wherein two lower support frames (232) are provided, and the lower support frames (232) are fixed to one end of the first frame (22) close to the liquid guiding device (3), and the lower support frame (232) is provided with at least two positioning holes (2321) located in the vertical direction, and the upper support frame (231) and the lower support frame (232) are positioned by means of a screw rod (2322) and a nut, and the screw rod (2322) passes through the positioning hole (2321).

7. The explosion-proof tubular plasma protein filter device according to claim 6, characterized in that: The axis of the liquid storage bottle (21) is at an angle of 75 degrees to the horizontal direction, and a groove (2311) capable of supporting storage is provided on the top of the upper support frame (231).

8. The explosion-proof tubular plasma protein filter device according to claim 7, characterized in that: The second stand (41) comprises: a support plate, the support plate is an L-shaped structure, the first side of the support plate is fixedly connected to the lower table (12), a connecting surface (13) is formed between the upper table (11) and the lower table (12) in the workbench (1), the second side of the support plate is in close contact with the connecting surface (13), the second side is protruded with a first support platform (411) and a second support platform (412), the first support platform (411) is provided with a first support ring (4111) whose inner diameter is the same as the outer diameter of the filter part (422) at one end close to the filter (42), the first support ring (4111) is for the filter (42) to pass through, and the first support ring (4111) is fixed to the outer wall of the filter (42), and a second support ring (4121) is fixed on the second support, the second support ring (4121) is for the bottom end of the filter (42) to pass through, and the second support ring (4121) supports the filter (42).

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