Ultrasonic ablation device

Abstract

The utility model relates to the technical field of medical intervention equipment, and provides an ultrasonic ablation device which comprises an ablation generating head and an ablation catheter. The ablation generation head comprises an ultrasonic transducer arranged in the ablation generation head and a peripheral balloon arranged on the peripheral part; one end of the ablation catheter is connected with the ablation generating head, and the other end is connected with the outdoor unit equipment; a pressure supply liquid path communicated with the peripheral balloon and a temperature control liquid path for controlling the temperature of the ablation generating head are arranged in the ablation catheter; an anti-skid positioning part is also arranged in the peripheral wall of the peripheral balloon; and the peripheral balloon can be expanded when the pressure supply liquid path is pressurized and can be retracted when the pressure supply liquid path is decompressed. The ultrasonic ablation device can be tightly attached to the inner wall of a pulmonary artery blood vessel of a patient through the anti-skid positioning part, the effect of accurately anchoring the ablation generating head and a to-be-ablated affected part is achieved, and real-time temperature control can be conducted on the ablation generating head through the temperature control liquid path; the problems of vascular intimal hyperplasia and stenosis caused by vascular wall injury due to ablation local high temperature are avoided.

Description

Technical Field

[0001] The present disclosure relates to the technical field of medical intervention devices, and particularly to an ultrasound ablation device. Background Art

[0002] In the prior art, the relatively common ablation instruments basically adopt two technologies: radiofrequency ablation and ultrasound ablation, but both of these technologies have certain drawbacks.

[0003] Radiofrequency ablation is to introduce radiofrequency current into human tissue. Due to the rapid change of the electromagnetic field, the polar water molecules in the tissue move at high speed, generating heat (i.e., the endothermal effect), causing the water inside and outside the cells to evaporate, dry, shrink and fall off, resulting in aseptic necrosis, so as to achieve the purpose of treatment. However, radiofrequency ablation requires good contact between the radiofrequency electrode and the blood vessel wall. With the performance of current radiofrequency catheters, effective mapping and ablation cannot be achieved in some parts. In addition, the heat energy generated by radiofrequency ablation is generated in the intima of the blood vessel in contact with the electrode and the nearby tissue, and the nerves located in the outer membrane are ablated through heat conduction. It is difficult to achieve effective ablation for nerves distributed deeper.

[0004] Ultrasound ablation is another ablation energy source that has been widely developed and studied after radiofrequency ablation, showing various advantages. Ultrasound ablation has good directivity and penetrability. Compared with radiofrequency ablation, the energy used in ultrasound ablation is lower, and the energy transfer does not depend on the conduction of the tissue.

[0005] However, ultrasound ablation also has certain disadvantages. When the ultrasonic energy is converted into heat for ablation in human tissue, the overheated surface of the converter may damage the intima of the blood vessels in the treatment area, which will lead to long-term vascular stenosis or even occlusion of the treatment object. Another example is in the blood. The ultrasonic element with an increased surface temperature will induce blood coagulation and agglomerate on the surface of the transducer, resulting in blocked sound energy release and further reducing the electroacoustic conversion efficiency of the ultrasonic transducer.

[0006] In addition, at present, most of the ultrasound ablations in the prior art are single-point or circumferential ablations, and the ablation targets do not have directivity and selectivity.

[0007] Therefore, there is an urgent need for a new type of ultrasound ablation device on the market to solve the problems that the surface of the converter in the existing ultrasound radiofrequency device may overheat and damage the intima of the blood vessels in the treatment area, and the ablation target may shift. Utility Model Content

[0008] The embodiments of the present disclosure provide an ultrasound ablation device for solving the problems that the surface of the existing ultrasound ablation device may overheat and damage the intima of the blood vessels in the treatment area, and the ablation target may shift.

[0009] The ultrasonic ablation device provided by the embodiments of the present disclosure includes an ablation generating head and an ablation catheter;

[0010] The ablation generating head includes an ultrasonic transducer disposed inside and a spherical balloon disposed on the outer periphery;

[0011] One end of the ablation catheter is connected to the ablation generating head, and the other end is connected to an external device;

[0012] Wherein, a pressure supply liquid path communicated with the spherical balloon and a temperature control liquid path for controlling the temperature of the ablation generating head are disposed inside the ablation catheter;

[0013] An anti-slip positioning portion is further disposed on the outer peripheral wall of the spherical balloon;

[0014] The spherical balloon can expand when the pressure supply liquid path is pressurized and contract when the pressure supply liquid path is depressurized.

[0015] In an implementable manner, the anti-slip positioning portion is set as a plurality of papilla points protruding from the outer peripheral wall of the spherical balloon;

[0016] The papilla points can be positioned and closely attached to the inner wall of the blood vessel when the spherical balloon expands.

[0017] In an implementable manner, a plurality of the papilla points are arranged at intervals in rows along the length direction of the spherical balloon;

[0018] And multiple rows of the papilla points are arranged at intervals in a ring shape along the circumferential wall direction of the spherical balloon.

[0019] In an implementable manner, the ultrasonic transducer has a piezoelectric crystal sheet;

[0020] The piezoelectric crystal sheet is electrically connected to an ultrasonic controller in the external device and can be regulated by the ultrasonic controller to control the magnitude of the ultrasonic energy output by itself.

[0021] In an implementable manner, the temperature control liquid path includes a circulating water inlet path and a circulating water outlet path disposed on the outermost layer of the ablation catheter wall;

[0022] The circulating water inlet path and the circulating water outlet path can be respectively connected to a water pump device in the external device.

[0023] In an implementable manner, both the circulating water inlet path and the circulating water outlet path are set as arc-shaped pipes consistent with the radian of the ablation catheter wall;

[0024] And the circulating water inlet path and the circulating water outlet path are arranged in an interlaced and wrapped manner on the outermost layer of the ablation catheter wall.

[0025] In one embodiment, a guidewire lumen for installing a guidewire is further provided at the inner center of the ablation catheter.

[0026] In one possible implementation manner, the ablation catheter is further provided with an isolation support layer between the guidewire lumen and its own tube wall.

[0027] In one possible implementation manner, a power electrode line is also disposed in the isolation support layer.

[0028] In one possible implementation manner, a connecting joint is protruding from the end of the ablation catheter connected to the external device.

[0029] Compared with the prior art, the technical solution provided by the embodiments of the present disclosure has the following advantages:

[0030] When the ultrasonic ablation device provided by the embodiment of the present disclosure is used, after the ablation head and the ablation catheter are correspondingly introduced into the target ablation area of ​​the patient's pulmonary artery, the pump fluid of the pressure supply fluid circuit is controlled by the external device to pressurize, so that the perispheric balloon of the ablation head is expanded and expanded, and the anti-slip positioning part is used to adhere to the inner wall of the patient's pulmonary artery blood vessel, thereby achieving the effect of accurately anchoring the ablation head to the patient's site to be ablated, so as to achieve the purpose of fixed-point ablation, and avoid the accidental detachment or displacement of the ablation head during the ablation process, causing incomplete ablation; and the external device can also perform real-time temperature control on the ablation head through the temperature control fluid circuit, thereby taking away excess ablation high temperature and cooling the blood vessel wall, which can prevent the local high temperature generated during ablation from causing damage to the blood vessel wall and causing hyperplasia and stenosis of the vascular endothelium.

[0031] It should be understood that the content described in this section is not intended to identify the key or important features of the embodiments of the present disclosure, nor is it intended to limit the scope of the present disclosure. Other features of the present disclosure will become easily understood through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] The above and other objects, features and advantages of the exemplary embodiments of the present disclosure will become readily understood by reading the detailed description below with reference to the accompanying drawings. In the accompanying drawings, several embodiments of the present disclosure are shown in an exemplary and non-limiting manner, in which:

[0033] In the drawings, the same or corresponding reference numerals represent the same or corresponding parts.

[0034] Figure 1 A schematic diagram of an ultrasonic ablation device provided by an embodiment of the present disclosure is shown;

[0035] Figure 2 A cross-sectional view of an ablation catheter in an ultrasonic ablation device provided in an embodiment of the present disclosure is shown.

[0036] Description of reference numerals in the figure: 1. Ablation generating head; 11. Ultrasonic transducer; 12. Peripheral balloon; 121. Anti-slip positioning part; 2. Ablation catheter; 21. Temperature control liquid path; 211. Circulating water inlet path; 212. Circulating water outlet path; 22. Guide wire lumen; 23. Isolation support layer; 24. Power electrode wire. Detailed implementation mode

[0037] To make the purpose, features, and advantages of the present disclosure more obvious and understandable, the following will combine the accompanying drawings in the embodiments of the present disclosure to clearly and completely describe the technical solutions in the embodiments of the present disclosure. Obviously, the described embodiments are only a part of the embodiments of the present disclosure, rather than all embodiments. Based on the embodiments in the present disclosure, all other embodiments obtained by those skilled in the art without creative efforts belong to the scope of protection of the present disclosure.

[0038] The following will describe the embodiments of the present disclosure in detail with reference to the accompanying drawings.

[0039] Combined with Figure 1 and Figure 2 As shown, the embodiment of the present disclosure provides an ultrasonic ablation device, which includes an ablation generating head 1 and an ablation catheter 2; the ablation generating head 1 includes an ultrasonic transducer 11 arranged inside and a peripheral balloon 12 arranged on the outer periphery; one end of the ablation catheter 2 is connected to the ablation generating head 1, and the other end is connected to an external device.

[0040] Among them, a pressure supply liquid path communicated with the peripheral balloon 12 and a temperature control liquid path 21 for controlling the temperature of the ablation generating head 1 are arranged inside the ablation catheter 2; an anti-slip positioning part 121 is also arranged on the outer peripheral wall of the peripheral balloon 12; the peripheral balloon 12 can expand when the pressure supply liquid path is pressurized and contract when the pressure supply liquid path is depressurized.

[0041] When the ultrasonic ablation device is specifically used, first connect one end of the ablation catheter 2 to the ablation generating head 1 and connect the other end of the ablation catheter 2 to an external device. Then, after the ablation generating head 1 and the ablation catheter 2 are correspondingly introduced into the target ablation area of the patient's pulmonary artery, the external device can control the pump pressure of the pressure supply liquid path to make the peripheral balloon 12 of the ablation generating head 1 expand, and the anti-slip positioning part 121 is used to tightly adhere to the inner wall of the patient's pulmonary artery blood vessel, so as to realize the function of accurately anchoring the ablation generating head 1 to the diseased area to be ablated, achieving the purpose of targeted ablation, and avoiding the effect of incomplete ablation caused by accidental detachment or displacement of the ablation generating head 1 during the ablation process. Moreover, the external device can also perform real-time temperature control on the ablation generating head 1 through the temperature control liquid path 21, thereby taking away the excess ablation heat and cooling the blood vessel wall, preventing the local high temperature generated during ablation from causing blood vessel wall damage and resulting in vascular intimal hyperplasia, stenosis, etc.

[0042] Compared with the ultrasonic ablation devices in the prior art, the ultrasonic ablation device provided by the embodiments of the present disclosure has the advantages of accurately positioning the diseased area to be ablated in the blood vessel, effectively avoiding the problems of accidental detachment or displacement of the ablation head 1 during the ablation process, and being able to perform real-time temperature control on the ablation head 1, effectively preventing local high temperature generated during ablation from causing vascular wall damage and resulting in vascular intimal hyperplasia, stenosis and other conditions.

[0043] In an implementable manner, the anti-slip positioning part 121 is arranged as a plurality of papilla points protruding from the outer peripheral wall of the circumferential balloon 12; the papilla points can be positioned and closely attached to the inner wall of the blood vessel when the circumferential balloon 12 expands and dilates.

[0044] Specifically, in Figure 1 Further detailed description, the anti-slip positioning part 121 is specifically arranged as a plurality of papilla points protruding from the outer peripheral wall of the circumferential balloon 12, and both the circumferential balloon 12 and the papilla points can adopt an integral structure and are prepared from a silicone material with a medical safety grade. In this way, when the circumferential balloon 12 is pumped and pressurized by the pump liquid of the external device to control the pressure liquid path, it can expand and dilate efficiently, and drive the papilla points to abut and position towards the blood vessel wall, realizing the function of accurately and effectively anchoring the ablation head 1 to the diseased area to be ablated in the blood vessel.

[0045] The above specific setting method of the anti-slip positioning part 121 has the beneficial effects of simple structure and being able to stably realize the effective anchoring of the ablation head 1 to the diseased area to be ablated in the blood vessel.

[0046] In an implementable manner, a plurality of papilla points are arranged at intervals in rows along the length direction of the circumferential balloon 12; and multiple rows of papilla points are arranged at intervals in a circumferential manner along the circumferential wall of the circumferential balloon 12.

[0047] Specifically, in Figure 1 Further detailed description, a plurality of papilla points are arranged at intervals in rows along the length direction of the circumferential balloon 12, and multiple rows of papilla points are arranged at intervals in a circumferential manner along the circumferential wall of the circumferential balloon 12. In this way, multiple papilla points in each row can effectively anchor the ablation head 1 to the inner wall of the blood vessel along the length direction of the circumferential balloon 12, and multiple rows of papilla points can effectively anchor the ablation head 1 to the inner wall of the blood vessel along the circumferential direction of the circumferential balloon 12, fully and effectively ensuring the positioning effect of the papilla points on the ablation head 1.

[0048] In an implementable manner, the ultrasonic transducer 11 has a piezoelectric crystal sheet; the piezoelectric crystal sheet is electrically connected to the ultrasonic controller in the external device and can be regulated by the ultrasonic controller to control the magnitude of the ultrasonic energy output by itself.

[0049] The piezoelectric crystal sheets can be specifically arranged in multiple different orientations in the ultrasonic transducer 11, and the ultrasonic controller in the external device can individually control or control the actual working states of multiple piezoelectric crystal sheets, so as to control the actual ultrasonic ablation direction of the ultrasonic transducer 11.

[0050] The piezoelectric effect of the piezoelectric crystal sheets converts electrical signals into mechanical vibrations. The working principle of the ultrasonic transducer 11 is that when the ultrasonic controller in the external device works, the electrical oscillation signals sent from the excitation power supply will cause changes in the electric or magnetic fields in the piezoelectric crystal sheets. This change generates a driving force on the mechanical vibration system of the transducer through a certain effect, causing it to enter the vibration state and radiate sound waves into the medium. The process of the ablation site in the blood vessel wall receiving sound waves is exactly the opposite. The external sound waves act on the ablation site, causing the ablation site to vibrate, and ablation is achieved by means of certain physical effects, including mechanical effects, cavitation effects, thermal effects, etc.

[0051] The piezoelectric crystal sheets can be specifically arranged as sheets distributed circumferentially along the outer periphery of the circumferential balloon 12. In this way, the piezoelectric crystal sheets have the ability to generate ultrasonic waves in all directions. At the same time, when the circumferential balloon 12 expands and adheres to the wall, the ultrasonic waves generated by the piezoelectric crystal sheets can directly penetrate the blood vessel inner wall, be transmitted into the tissue, and act on the nerve fibers. The action site is closer, the energy loss of ultrasonic transmission is lower, the action depth is farther, the required energy is smaller, the thermal effect on the blood vessel inner wall is smaller, which is more conducive to circulating cooling control and reduces blood vessel damage. The action is more precise and the effect is more obvious.

[0052] The above specific setting method of the ultrasonic transducer 11 has the beneficial effects of simple structure and being able to be sensitively regulated by the ultrasonic controller for ultrasonic ablation energy.

[0053] In an implementable manner, the temperature control liquid path 21 includes a circulating water inlet path 211 and a circulating water outlet path 212 arranged on the outermost layer of the wall of the ablation catheter 2; the circulating water inlet path 211 and the circulating water outlet path 212 can be respectively connected to the water pump device in the external device.

[0054] Specifically, in combination with Figure 1 and Figure 2 For further detailed description, the temperature control liquid path 21 is specifically set as the circulating water inlet path 211 and the circulating water outlet path 212 located on the outermost layer of the wall of the ablation catheter 2. In this way, the circulating water inlet path 211 and the circulating water outlet path 212 can be respectively connected to the water pump device in the external device, so as to achieve the beneficial effect of real-time and efficient temperature control of the ablation occurrence head 1 by means of pumping cooling water through the circulating pump.

[0055] In one implementable embodiment, both the circulating water inlet path 211 and the circulating water outlet path 212 are arranged as arc-shaped tubes that are consistent with the arc of the wall of the ablation catheter 2; and the circulating water inlet path 211 and the circulating water outlet path 212 are arranged in an interleaved and wrapped manner on the outermost layer of the wall of the ablation catheter 2.

[0056] Specifically, in Figure 2 Further detailed description, both the circulating water inlet path 211 and the circulating water outlet path 212 are arranged as arc-shaped tubes that are consistent with the arc of the wall of the ablation catheter 2, and the circulating water inlet path 211 and the circulating water outlet path 212 are arranged in an interleaved and wrapped manner on the outermost layer of the wall of the ablation catheter 2. In this way, on the one hand, it can increase the effective contact area between the circulating water inlet path 211, the circulating water outlet path 212 and the wall of the ablation catheter 2. On the other hand, there can also be a sufficiently large adjacent contact area between the circulating water inlet path 211 and the circulating water outlet path 212, so as to more conveniently perform heat exchange between the circulating water inlet path 211 and the circulating water outlet path 212, make the overall temperature of the temperature control liquid path 21 more uniform, and be able to perform temperature control heat exchange with the ablation head 1 more efficiently.

[0057] In one implementable embodiment, a guide wire lumen tube 22 for installing a guide wire is further provided at the inner center of the ablation catheter 2.

[0058] Specifically, in Figure 2 Further detailed description, a guide wire lumen tube 22 for installing a guide wire is provided at the inner center of the ablation catheter 2. In this way, the guide wire is inserted into it, and through the guiding action of the guide wire, the penetration efficiency of the ablation head 1 in the blood vessel can be accurately improved.

[0059] In one implementable embodiment, an isolation support layer 23 is further provided between the guide wire lumen tube 22 and the wall of the ablation catheter 2 itself.

[0060] Specifically, in Figure 2 Further detailed description, an isolation support layer 23 is provided between the guide wire lumen tube 22 and the wall of the ablation catheter 2 itself. The isolation support layer 23 can ensure that the ablation catheter 2 as a whole has a certain shape support rigidity, and ensure the high efficiency and convenience of the ablation catheter 2 during guiding and threading in the blood vessel.

[0061] In one implementable embodiment, a power electrode wire 24 is further provided in the isolation support layer 23.

[0062] Specifically, in Figure 2 Further detailed description, the power electrode wire 24 is arranged in the isolation support layer 23. In this way, the installation protection effect on the power electrode wire 24 can be improved through the wrapping rigidity of the isolation support layer 23.

[0063] In one implementable embodiment, a connection joint is protrudingly provided at the end of the ablation catheter 2 connected to the external device.

[0064] Specifically, in combination with Figure 2 For further detailed description, the connection joint of the temperature control liquid path 21 can be specifically set as a sealed docking joint, and the connection joint of the power electrode wire 24 can be specifically set as a plug-in docking joint. Such setting of multiple types of connection joints can fully facilitate the separate connection with the multi-functional external machine equipment.

[0065] In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of such features. In the description of the present disclosure, "a plurality of" means two or more unless otherwise specifically defined.

[0066] As described above, it is only the specific implementation manner of the present disclosure, but the protection scope of the present disclosure is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present disclosure can easily think of changes or substitutions, which should all be covered within the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure should be subject to the protection scope of the claims.

Claims

1. An ultrasonic ablation device, characterized in that: include: The ablation head (1) comprises an ultrasonic transducer (11) arranged inside and a perispherical balloon (12) arranged on the periphery; An ablation catheter (2), one end of which is connected to the ablation head (1), and the other end of which is connected to an external device; Wherein, the ablation catheter (2) is provided with a pressure supply liquid circuit connected to the perispheric balloon (12), and a temperature control liquid circuit (21) for controlling the temperature of the ablation head (1); An anti-slip positioning portion (121) is also provided in the outer peripheral wall of the perispheric balloon (12); The perispheric balloon (12) can expand when the pressure supply fluid circuit is pressurized, and can shrink when the pressure supply fluid circuit is depressurized.

2. The ultrasonic ablation device according to claim 1, characterized in that: The anti-slip positioning portion (121) is configured as a plurality of mastoid points protruding from the outer peripheral wall of the perispherical sac (12); The mastoid point can be positioned and closely attached to the inner wall of the blood vessel when the perispheric balloon (12) is expanded.

3. The ultrasonic ablation device according to claim 2, characterized in that: The mastoid points are arranged in a plurality of rows and intervals along the length direction of the perispherical sac (12); Furthermore, multiple rows of mastoid points are arranged in an annular manner at intervals along the peripheral wall of the perispherical sac (12).

4. The ultrasonic ablation device according to claim 1, characterized in that: The ultrasonic transducer (11) has a piezoelectric crystal plate; The piezoelectric crystal sheet is electrically connected to an ultrasonic controller in an external device, and the ultrasonic controller can control the ultrasonic energy outputted by the piezoelectric crystal sheet.

5. The ultrasonic ablation device according to claim 1, characterized in that: The temperature-controlled liquid circuit (21) comprises a circulating water inlet circuit (211) and a circulating water outlet circuit (212) arranged on the outermost layer of the tube wall of the ablation catheter (2); The circulating water inlet (211) and the circulating water outlet (212) can be connected to a water pump device in an external device respectively.

6. The ultrasonic ablation device according to claim 5, characterized in that: The circulating water inlet (211) and the circulating water outlet (212) are both configured as arc-shaped tubes having the same curvature as the tube wall of the ablation catheter (2); Furthermore, the circulating water inlet path (211) and the circulating water outlet path (212) are arranged in an interlaced manner and wrapped around each other on the outermost layer of the wall of the ablation catheter (2).

7. The ultrasonic ablation device according to claim 1, characterized in that: A guidewire lumen (22) for installing a guidewire is also provided at the inner center of the ablation catheter (2).

8. The ultrasonic ablation device according to claim 7, characterized in that: The ablation catheter (2) is also provided with an isolation support layer (23) between the guidewire lumen (22) and its own tube wall.

9. The ultrasonic ablation device according to claim 8, characterized in that: A power supply electrode line (24) is also arranged in the isolation support layer (23).

10. The ultrasonic ablation device according to claim 1, characterized in that: The end of the ablation catheter (2) connected to the external equipment is protrudingly provided with a connecting joint.

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