Tool structure for installing objective lens on motor

Abstract

The utility model provides a frock structure for installing the objective lens on the motor, the objective lens and the motor after installation are applied to the gene sequencing technical instrument, the frock structure comprises a vertical frame and a motor fixing block arranged on the vertical frame, the motor fixing block comprises a clamping groove and a fastening piece, the clamping groove is used for clamping the motor, the fastening piece is used for fastening the motor, and the fastening piece is used for fastening the motor. The fastening piece fastens the motor clamped in the clamping groove so that the objective lens can be installed on the motor. According to the technical scheme, the technical problems of inconvenience and risk caused by manual installation of the objective lens in the prior art are solved.

Description

Technical Field

[0001] The utility model relates to the technical field of gene sequencing, in particular to a tooling structure for installing an objective lens on a motor. Background Art

[0002] During the installation of a gene sequencer, it is necessary to first install the objective lens on the motor, and then install the whole of the objective lens and the motor on the gene sequencer. The existing method for installing the objective lens is generally to directly manually install the objective lens on the motor, that is, to hold the motor with one hand and the objective lens with the other hand, and screw the objective lens onto the motor mover. During the installation process, the motor mover will be subjected to a twisting force during screwing, and the force acts on the motor guide rail through the motor mover. For a motor with very high precision, there is a risk of damaging the motor with this installation method. Summary of the Invention

[0003] The utility model provides a tooling structure for installing an objective lens on a motor, so as to solve the technical problems of inconvenience and risk brought by directly manually installing the objective lens in the prior art.

[0004] The utility model provides a tooling structure for installing an objective lens on a motor. The objective lens and the motor are applied to a gene sequencer. The tooling structure includes a vertical frame and a motor fixing block arranged on the vertical frame. The motor fixing block includes a clamping groove and a fastening member. The clamping groove is used for clamping the motor, and the fastening member fastens the motor clamped in the clamping groove so as to facilitate the installation of the objective lens on the motor.

[0005] Optionally, the clamping groove includes a vertical groove and a clamping plate horizontally arranged in the vertical groove.

[0006] Optionally, the fastening member is a fastening bolt arranged in a threaded hole penetrating through the side wall of the vertical groove.

[0007] Optionally, the fastening bolt is located above the clamping plate.

[0008] Optionally, the clamping groove is used for clamping the motor mover of the motor, and the fastening bolt abuts against the side surface of the motor mover to fix it.

[0009] Optionally, the vertical frame includes a vertical plate and a bottom plate. The motor fixing block is arranged at the upper end of the vertical plate, and the bottom plate is connected to the bottom end of the vertical frame.

[0010] Optionally, the motor fixing block and the bottom plate extend along the same side of the vertical plate.

[0011] Optionally, a soft pad is laid on the upper side of the bottom plate.

[0012] Optionally, a soft pad is laid on the side surface of the vertical plate facing the extending direction of the motor fixing block.

[0013] Optionally, the motor is a voice coil motor or a linear motor.

[0014] To make the features and advantages of the present application more obvious and understandable, some embodiments are specifically given below and will be described in detail in conjunction with the accompanying drawings as follows. Description of the Drawings

[0015] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention, and for those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0016] Figure 1 It is a schematic structural diagram of a gene sequencing system / instrument;

[0017] Figure 2 It is a schematic structural diagram of an optical detection system;

[0018] Figure 3 It is a schematic structural diagram of a tooling structure for mounting an objective lens to a motor in an embodiment of the present invention;

[0019] Figure 4 It is a schematic structural diagram of a motor in an embodiment of the present invention;

[0020] Figure 5 It is a schematic structural diagram after the objective lens is mounted in an embodiment of the present invention.

[0021] In the figure: 1. Motor fixing plate; 1-1. Vertical groove; 1-2. Clamping plate; 2. Vertical plate; 2-1. Vertical plate soft pad; 3. Bottom plate; 3-1. Bottom plate soft pad; 4. Tightening bolt; 5. Motor; 5-1. Voice coil motor; 5-2. Motor mover; 5-21. Step structure; 5-3. Objective lens mounting bracket; 10. Chip; 20. Chip platform; 30. Reagent storage container; 40. Diversion system; 50. Optical detection system; 501. Light source assembly; 502. Imaging assembly; 5021. Field stop sheet I; 5022-1. Dichroic mirror I; 5022-2. Dichroic mirror II; 5022-3. Dichroic mirror III; 5023. Microscope; 50231. Objective lens; 50232. Tube lens; 5024. Image sensor; 5026. Attenuator; 5027. Collimating element; 60. Computer system; (701, 702) Light source; 703. Field stop sheet II; 704. Field stop sheet III; 705. Filter. Detailed Embodiments

[0022] In order to make the purpose, technical solution and advantages of the utility model clearer, the technical solution of the utility model will be described in detail below. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other implementation methods obtained by ordinary technicians in this field without creative work belong to the scope of protection of the utility model.

[0023] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be an intermediate element at the same time. When an element is referred to as being "connected to" another element, it may be directly connected to the other element or there may be an intermediate element at the same time.

[0024] Figure 1 Figure 1 is a schematic diagram of the structure of a gene sequencing system / instrument. Figure 1 As shown, the gene sequencing system provided by the embodiment of the present disclosure includes: a chip 10, a chip platform 20, a reagent storage container 30, a flow guidance system 40, an optical detection system 50 and a computer system 60.

[0025] Among them, one or more sequencing objects are attached to the chip 10; the sequencing object here can be a DNA / RNA fragment, and the DNA / RNA fragment includes a base sequence of a certain length, for example, 150bp in length; the sequencing object can also be a DNA / RNA molecule.

[0026] A chip platform 20 configured to fix and support the chip 10;

[0027] The reagent storage container 30 is configured to store one or more reagents; here, the reagents may exemplarily include polymerase chain reaction (PCR) fluorescent reagents.

[0028] The flow guiding system 40 is configured to controllably transport the one or more reagents from the reagent storage container 30 to the chip 10 so as to contact with the sequencing object and undergo a chemical reaction, so that the sequencing object is marked with a fluorescent marker;

[0029] An optical detection system 50 is configured to excite the fluorescent marker carried by the sequencing object and detect the fluorescent signal generated by the excited fluorescent marker;

[0030] The computer system 60 is configured to obtain the fluorescent image from the optical detection system 50 and identify the gene sequence of the sequencing object according to the fluorescent image.

[0031] Figure 2Schematic structural diagram of the optical detection system 50. The optical detection system 50 at least includes a light source assembly 501 and an imaging assembly 502. Among them, the light source assembly 501 includes light sources (701, 702), a field stop sheet II 703, a field stop sheet III 704, a dichroic mirror II 5022-2, and a filter element 705. Among them, in one implementation, the light sources (701, 702) can be light-emitting diodes (LEDs). The LED is an aspherical mirror and can diverge the LED point light source into parallel light. Of course, in addition to LEDs, other forms of point or surface light sources can also be used. In another implementation, a collimating element ( Figure 2 not shown in the figure) can be provided behind the light source to collimate the light emitted by the light sources (701, 702) into a parallel light beam. The collimating element can include one or more lenses, including but not limited to any one or any combination of single lenses, cemented lenses, spherical lenses, and aspherical lenses.

[0032] The parallel light beam is emitted through the field stop sheet II 703 and the field stop sheet III 704. The field stop sheet II 703 and the field stop sheet III 704 define the field of view range of the light emitted by the light sources (701, 702) and the field of view range of the excitation light irradiated on the chip 10. The light passing through the field stop sheet II 703 and the field stop sheet III 704 irradiates the dichroic mirror I 5022-1. The dichroic mirror II 5022-2 can transmit one of the light sources (701, 702) and reflect the other light source, and irradiate the light sources (701, 702) on the filter element 705. The filter element 705 allows the light of the required wavelength band in the light emitted by the light sources (701, 702) to pass through and serves as the excitation light, while blocking the light of other wavelength bands. For example, it blocks the wavelength band that is the same as the fluorescence emitted by the sequencing object, ensuring that the fluorescence emitted by the sequencing object does not contain stray light introduced by the light source, which helps to improve the optical imaging effect of the sequencing object.

[0033] In one implementation, the dichroic mirror II 5022-2 can be fixed at a certain angle and inclined, for example, fixed by dispensing. In another implementation, the field stop sheet II 703 and the field stop sheet III 704 can be, but are not limited to, rectangular diaphragms or circular diaphragms; the field stop sheet II 703 and the field stop sheet III 704 can be single-hole or multi-hole diaphragm sheets; the field stop sheet II 703 and the field stop sheet III 704 can be made of light-blocking materials, for example, metal sheets.

[0034] Here, it should be noted that in the optical detection system 50, the light sources (701, 702) emit light alternately, not simultaneously. By operating the two light sources in a time-sharing manner (i.e., the light wavelengths emitted by the light sources 701 and 702 are different, and they are turned on in turn when in use), only one light source is turned on at a time, which will reduce the light power of the excitation light irradiated to the chip, which is beneficial to protecting the fluorescence lifetime of the fluorescent group on the sequencing object.

[0035] The imaging component 502 at least includes a dichroic mirror I 5022-1, a microscope 5023 (including an objective lens 50231 and a tube lens 50232), and an image sensor 5024. The LED light emitted by the light source component 501 is irradiated to the dichroic mirror I 5022-1, and the dichroic mirror I 5022-1 reflects the LED light to the chip 10. The LED light is used as excitation light to excite the fluorescent group on the sequencing object. The fluorescent group generates a fluorescent signal after being excited. The fluorescent signal is collected by the objective lens 50231 and irradiated to the dichroic mirror I 5022-1. The dichroic mirror I 5022-1 transmits the fluorescent signal to the tube lens 50232. The tube lens 50232 projects the fluorescent signal to the image sensor 5024. The image sensor 5024 collects the fluorescent signal and generates a fluorescent image. The computer system 60 identifies the gene sequence of the sequencing object according to the fluorescent image. In one embodiment, the image sensor 5024 can be an industrial camera.

[0036] In one embodiment, the imaging assembly 502 further includes a collimating element 5027, which is located between the filter 705 and the dichroic mirror I 5022-1 and is configured to collimate the LED light into a parallel beam. The collimating element 5027 may include one or more lenses, including but not limited to any one or any combination of a single lens, a cemented lens, a spherical lens, and an aspherical lens.

[0037] In another embodiment, a filter element ( Figure 2 ), a filter element (not shown) is provided between the tube lens 50232 and the image sensor 504. Figure 2 not shown).

[0038] In addition, to achieve focusing, the imaging assembly 502 further includes a focusing light source 501, a field stop sheet I 5021, an attenuation sheet 5026, and a dichroic mirror III 5022-3. In a possible implementation, the focusing light source 501 is, for example, a laser diode (LD) and emits laser light for focusing. The dichroic mirror III 5022-3 can be fixed at an angle by, for example, dispensing. The field stop sheet I 5021 can be a single-hole or multi-hole stop sheet. The field stop sheet I 5021 can be made of a light-impermeable material, for example, a metal sheet. The laser light for focusing can only pass through the light-passing holes of the corresponding field stop sheet, while the non-light-passing holes of the field stop sheet will block the laser light.

[0039] After the laser light emitted by the laser 501 passes through the field stop sheet I 5021, it forms parallel laser light. The parallel laser light irradiates the attenuation sheet 5026. After the laser light is attenuated by the attenuation sheet 5026, it irradiates the dichroic mirror III 5022-3. The dichroic mirror III 5022-3 can transmit the laser light and reflect the LED light. The laser light transmitted by the dichroic mirror III 5022-3 irradiates the convex lens 5027. The convex lens 5027 is also configured to collimate the laser light into a parallel light beam and irradiate the dichroic mirror I 5022-1. The dichroic mirror I 5022-1 reflects the laser light onto the chip 10. The laser light serves as excitation light to excite the fluorescence labels carried on the sequencing target. The fluorescence labels generate fluorescence signals after being excited. The fluorescence signals are collected by the objective lens 50231 and irradiate the dichroic mirror I 5022-1. The dichroic mirror I 5022-1 transmits the fluorescence signals to the tube lens 50232. The tube lens 50232 projects the fluorescence signals onto the image sensor 5024. The image sensor 5024 collects the fluorescence signals and generates a fluorescence image. The computer system 60 identifies the image quality based on the fluorescence image. A motor is configured on one side of the objective lens 50231. In one implementation, the motor can be, for example, a voice coil motor or other linear motor. Based on the image quality of the fluorescence image identified by the computer system 60, the voice coil motor can be controlled to drive the objective lens 50231 to move up and down to achieve focusing of the imaging assembly 502 and obtain the best image quality of the fluorescence image.

[0040] In Figure 2In the structure of the optical detection system 50 shown, the objective lens 50231 is installed on a motor, and then the objective lens 50231 together with the motor as a whole is installed in the optical detection system 50 of the gene sequencer. As described in the background art, the existing installation method generally directly manually installs the objective lens 50231 and the motor, that is, by holding the motor 50231 with one hand and the objective lens with the other hand, and screwing the objective lens 50231 onto the motor mover. During the installation process, the motor mover will be subjected to the twisting force of screwing, and the force acts on the motor guide rail through the motor mover. For a motor with very high precision, there is a risk of damaging the motor by this installation method.

[0041] To solve this technical problem, this case provides a tooling structure.

[0042] Figure 3 It is a schematic structural diagram of the tooling structure for installing the objective lens onto the motor in the embodiment of the present invention, as Figure 3 shown:

[0043] The present invention provides a tooling structure for installing an objective lens onto a motor. The objective lens 50231 and the motor are applied to a gene sequencer. The tooling structure includes a vertical frame and a motor fixing block 1 provided on the vertical frame. The motor fixing block 1 includes a slot and a fastener. The slot is used to clamp the motor, and the fastener fastens the motor clamped in the slot to facilitate installing the objective lens 50231 on the motor.

[0044] Specifically, after fixing the motor through the motor fixing block 1, then install and connect the objective lens 50231 and the motor, avoiding the influence on the relevant components of the motor during the manual installation process when the objective lens is being screwed under the holding state.

[0045] In some embodiments, the slot includes a vertical slot 1-1 and a clamping plate 1-2 horizontally arranged in the vertical slot 1-1.

[0046] Specifically, a vertical slot 1-1 is vertically arranged on one side of the motor fixing block 1 so that the corresponding components of the motor can be clamped therein. A clamping plate 1-2 is arranged at the lower part of the vertical slot 1-1, which is beneficial for the clamping positioning and support of the motor.

[0047] In some embodiments, the fastener is a fastening bolt 4, which is arranged in a threaded hole penetrating the side wall of the vertical slot 1-1.

[0048] In some embodiments, the fastening bolt 4 is located above the clamping plate 1-2.

[0049] Specifically, when the motor is clamped in the slot, the fastening bolt 4 is screwed into the vertical slot 1-1 through the threaded hole and abuts against the side of the relevant part of the motor, fastening the motor in the slot.

[0050] In some embodiments, the card slot is used to clamp the motor mover 5-2 of the motor, and the fastening bolt 4 abuts against the side surface of the motor mover 5-2 to fix it.

[0051] Specifically, as Figure 4 , Figure 5 shown, the motor is a voice coil motor or a linear motor; one end of the motor mover 5-2 is connected to the voice coil motor 5-1, and the other end is connected to the objective lens mounting bracket 5-3. The voice coil motor 5-1 is fixed by being clamped on the motor mover 5-2 through the card slot; corresponding to the stepped structure 5-21 of the motor mover 5-2, the clamping plate 1-2 is provided, and the clamping plate 1-2 is clamped at the stepped structure 5-21 to support the motor.

[0052] In some embodiments, the vertical frame includes a vertical plate 2 and a bottom plate 3. The motor fixing block 1 is arranged at the upper end of the vertical plate 2, and the bottom plate 3 is connected to the bottom end of the vertical frame 2.

[0053] Specifically, mounting holes can be provided on the bottom plate 3. The tooling structure can be fixed on the operating table through the bottom plate 3, and then the motor is installed on the motor fixing block 1.

[0054] In some embodiments, the motor fixing block 1 and the bottom plate 3 extend along the same side of the vertical plate 2.

[0055] Specifically, the motor fixing block 1 and the bottom plate 3 extend along the same side of the vertical plate 2, which enhances the structural stability and has a simple structure.

[0056] In some embodiments, a soft pad is laid on the upper side of the bottom plate 3.

[0057] In some embodiments, a soft pad is laid on the side surface of the vertical plate 2 facing the extending direction of the motor fixing block 1.

[0058] Specifically, the soft pads are arranged on the side surfaces facing the motor during the installation of the motor, including the bottom plate soft pad 3-1 and the vertical plate soft pad 2-1, which are used to protect the motor and avoid damage caused by bumps. The soft pads can adopt soft anti-collision structures such as foamed silica gel.

[0059] Based on the above tooling structure for objective lens installation, the installation process is as follows:

[0060] First, lock the bottom plate 3 on the operating platform, then install the motor mover 5-2 into the corresponding vertical groove 1-1 of the motor fixing block 1, and ensure that only the motor mover 5-2 contacts the tooling of the present invention. Then tighten the fastening bolt 4 until the motor mover 5-2 is locked. After locking, install the objective lens 50231 on the objective lens mounting bracket 5-3 on the motor mover 5-2. At this time, all the locking forces are applied to the motor mover 5-2, and the guide rail on the voice coil motor 5-1 will not be stressed.

[0061] The structure of the present invention is simple and the operation is simple, which can effectively reduce the risk of motor damage; compared with the prior art, the installation method of the present invention is unified, more professional and convenient, and the efficiency is improved.

[0062] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present utility model. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0063] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the terms "installed", "connected", "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.

[0064] The above is only the specific implementation manner of the present utility model, but the protection scope of the present utility model is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present utility model can easily think of changes or substitutions, which should all be covered within the protection scope of the present utility model. Therefore, the protection scope of the present utility model should be subject to the protection scope of the claimed rights.

Claims

1. A tooling structure for mounting an objective lens on a motor, characterized in that: The objective lens and the motor are applied to a gene sequencer. The tooling structure includes a stand and a motor fixing block arranged on the stand. The motor fixing block includes a slot and a fastener. The slot is used to clamp the motor. The fastener fastens the motor clamped in the slot to facilitate the installation of the objective lens on the motor.

2. The tooling structure for mounting an objective lens on a motor according to claim 1, characterized in that: The card slot comprises a vertical slot and a card connection plate which is transversely arranged in the vertical slot.

3. The tooling structure for mounting an objective lens on a motor according to claim 2, characterized in that: The fastener is a fastening bolt, which is arranged in a threaded hole that passes through the side wall of the vertical groove.

4. The tooling structure for mounting an objective lens on a motor according to claim 3, characterized in that: The fastening bolt is located above the clamping plate.

5. The tooling structure for mounting an objective lens on a motor according to claim 4, characterized in that: The clamping groove is used for clamping the motor mover of the motor, and the fastening bolt abuts against the side surface of the motor mover to fix it.

6. The tooling structure for mounting an objective lens on a motor according to any one of claims 1 to 5, characterized in that: The stand comprises a stand plate and a bottom plate, the motor fixing block is arranged on the upper end of the stand plate, and the bottom plate is connected to the bottom end of the stand.

7. The tooling structure for mounting an objective lens on a motor according to claim 6, characterized in that: The motor fixing block and the bottom plate are extended along the same side of the vertical plate.

8. The tooling structure for mounting an objective lens on a motor according to claim 7, characterized in that: The upper side of the bottom plate is paved with a soft cushion.

9. The tooling structure for mounting an objective lens on a motor according to claim 8, characterized in that: A soft cushion is laid on the side of the vertical plate facing the extending direction of the motor fixing block.

10. The tooling structure for mounting an objective lens on a motor according to claim 1, characterized in that: The motor is a voice coil motor or a linear motor.

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