Pretreatment incubation luminoscope

By introducing an incubation function in the fluorometer, and accelerating biological or chemical reactions with electrical heating and constant temperature control, the problems of instability and low efficiency of existing fluorometers are solved, and the acceleration of reactions and the efficiency of experimental operations are achieved.

CN222965119UActive Publication Date: 2025-06-10YANTAI YUANQIN TECH DEV CO LTD
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Patent Information

Application Number
CN202421889470.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-06
Publication Date
2025-06-10
Estimated Expiration
2034-08-06

AI Technical Summary

Technical Problem

The existing fluorescence instruments lack incubation function and cannot speed up biological reactions or chemical reactions, resulting in unstable reactions, long experimental operation and detection time, and low working efficiency.

Method used

A pretreatment incubation fluorescence meter is designed, including a test strip carrier, an electric heating plate, a temperature sensor and a detection transmission assembly. The test sample and test strip are driven by a side-shift motor and a side-shift synchronization belt, and the reaction is accelerated by electric heating and constant temperature control.

Benefits of technology

It achieves acceleration and stability of biological reactions or chemical reactions, shortens the experimental operation and detection time, and improves the efficiency of staff.

✦ Generated by Eureka AI based on patent content.

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Abstract

A detection head and a display are both electrically connected with a master controller, a test paper carrier and a test paper lifting mechanism used for lifting the test paper carrier are arranged in a shell, a plurality of test paper clamping shells used for inserting test paper are movably connected to the test paper carrier, a test paper cover plate is connected to the test paper carrier through bolts, and the test paper cover plate is in threaded connection with the test paper lifting mechanism. An electric heating plate is fixedly connected to the test paper cover plate, a plurality of temperature sensors are arranged on the side wall of the test paper carrying frame, a distance sensor is fixedly connected to the detection head, and a sample placing frame, a lateral movement motor, a lateral movement synchronous belt, a synchronous transmission assembly and a tensioning adjusting assembly used for adjusting tensioning of the lateral movement synchronous belt are further arranged in the shell; the sample placing frame is fixedly connected with a sample synchronous clamp, the sample synchronous clamp is clamped on the lateral moving synchronous belt, and the tension adjusting assembly is erected on the lateral moving synchronous belt. According to the utility model, the reaction can be accelerated, more sufficient and more stable, the detection time of experimental operation is greatly shortened, and the efficiency of workers is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of detection instruments, and in particular to a pretreatment incubation fluorometer. Background Art

[0002] A fluorometer is an instrument for qualitative and quantitative analysis. Through the detection of the fluorometer, information such as the excitation spectrum, emission spectrum, quantum yield, fluorescence intensity, fluorescence lifetime, Stokes shift, fluorescence polarization and depolarization characteristics, and fluorescence quenching of substances can be obtained. The incubation fluorometer is mainly used for fluorescence detection after the incubation of various enzyme-linked immunosorbent assay kits and enzyme-catalyzed chemiluminescence immunoassays in medical institution laboratories. Incubation can accelerate and make the biological reaction or chemical reaction more sufficient, and reduce the within-batch difference of the reaction within a batch through incubation, making the reaction linear more stable, greatly shortening the time for experimental operation and detection, improving the efficiency of staff, and playing a wide role in the application fields of medicine and biology.

[0003] The existing Chinese patent with the name of a microsphere fluorometer and the patent number of CN214622323U includes a device main body. The device main body includes a fluorometer main body. A control panel is installed at the top end of the fluorometer main body. A hinge is installed at the top end of the fluorometer main body on one side of the control panel. A closing plate is installed on one side of the hinge. A fixing spring is installed on the side of the closing plate away from the hinge. The other end of the fixing spring is installed with a fixing block. A fixing groove is opened on the side of the fluorometer main body close to the fixing block, and the fixing block extends into the fixing groove. An empty groove is opened inside the fluorometer main body at the bottom end of the closing plate. Telescopic rods are installed on both sides of the inner wall of the empty groove. The other ends of the two telescopic rods are installed with a glass placement plate. A sleeve spring is sleeved on the outer surface of the telescopic rod. Cleaning mechanisms are installed on both sides of the control panel. Through the elastic force of the winding rod, the movable moving plate moves towards the direction close to the glass placement plate, so that the movable fixing plate can fix the test strip placed by the staff, thus facilitating the subsequent test strip detection.

[0004] Although the existing fluorometer will not cause the movement of the test strip due to the closing of the cabin door, which affects the detection result, the existing fluorometer lacks an incubation function, cannot accelerate the biological reaction or chemical reaction, cannot make the reaction more stable and sufficient, nor can it shorten the time for experimental operation and detection, and the work efficiency is not high. Therefore, the utility model provides a pretreatment incubation fluorometer to solve the above problems. Summary of the Utility Model

[0005] The purpose of the utility model is to overcome the shortcomings of the above-mentioned traditional technology and provide a pre-treatment incubation fluorescence instrument, which can accelerate and make biological or chemical reactions more complete, make the reaction linearity more stable, greatly shorten the experimental operation and detection time, and improve the efficiency of the staff.

[0006] The purpose of this utility model is achieved through the following technical measures:

[0007] A pretreatment incubation fluorescence instrument comprises a shell, a main controller, a display and a detection head for detecting the test results of the test paper. The display is embedded in the shell, the main controller and the detection head are both arranged in the shell, the detection head and the display are both electrically connected to the main controller, a test paper carrier and a test paper lifting mechanism for lifting the test paper carrier are arranged in the shell, the test paper lifting mechanism is connected to the inner bottom surface of the shell, the test paper carrier is fixedly connected to the test paper lifting mechanism, a plurality of test paper card shells for inserting test papers are movably connected to the test paper carrier, a test paper cover plate is bolted to the test paper carrier, an electric heating plate is fixedly connected to the side of the test paper cover plate close to the test paper carrier, a plurality of temperature sensors are arranged on the side wall of the test paper carrier, a detection fixing frame is arranged in the shell, a driving A detection transmission assembly for moving the detection head, the detection head is located on the side of the detection cover away from the test paper carrier, a distance sensor is fixedly connected to the detection head, a sample placement rack, a side shift motor, a side shift synchronous belt, a synchronous transmission assembly and a tension adjustment assembly for adjusting the tension of the side shift synchronous belt are also arranged in the shell, the side shift motor is fixedly arranged in the shell, the synchronous transmission assembly is connected to the side shift motor, the side shift synchronous belt is driven to rotate by the synchronous transmission assembly, a sample synchronous clamp is fixedly connected to the sample placement rack, the sample synchronous clamp is clamped on the side shift synchronous belt, the tension adjustment assembly is arranged on the side of the side shift motor close to the side shift synchronous belt and is mounted on the side shift synchronous belt, the distance sensor, the detection transmission assembly, the test paper lifting mechanism and the side shift motor are all electrically connected to the main controller.

[0008] Further specific optimization, the synchronous transmission assembly includes a main transmission wheel and two auxiliary transmission wheels, the main transmission wheel is mounted on the output end of the side shift motor, the two auxiliary transmission wheels are rotatably connected to the bottom of the outer shell, the main transmission wheel and the two auxiliary transmission wheels are rotatably connected to the inner side of the side shift synchronous belt and are arranged in parallel, the two auxiliary transmission wheels are located on the same horizontal line, the main transmission wheel is located between the two auxiliary transmission wheels and is arranged higher than the two auxiliary transmission wheels.

[0009] Further specific optimization, the tensioning adjustment assembly includes a tensioning adjustment wheel, a tensioning fixed wheel and a roller fixing frame, the roller fixing frame is fixedly connected to the side shift motor, the tensioning adjustment wheel and the tensioning fixed wheel are respectively located on both sides of the main drive wheel, the tensioning adjustment wheel and the tensioning fixed wheel are rotatably connected to the outer side of the side shift synchronous belt, the tensioning fixed wheel is rotatably connected to the roller fixing frame, the tensioning adjustment wheel is rotatably connected to a driving block, and the driving block is bolted to the roller fixing frame.

[0010] For further specific optimization, the detection drive assembly includes a detection motor and a detection transmission belt. The detection motor is fixedly connected to the detection fixing bracket, and the detection motor drives the detection transmission belt to rotate. A detection fixing clip is clamped on the detection transmission belt, and the detection head is fixedly connected to the detection fixing clip. The detection motor is electrically connected to the main controller.

[0011] For further specific optimization, a plurality of cartridge slots are provided on the test strip carrier. The number of temperature sensors is the same as the number of cartridge slots and they are correspondingly arranged in the cartridge slots one by one. Each test strip cartridge is correspondingly arranged in the cartridge slots. Two slot holes are provided in each cartridge slot, and a magnet block is fixedly connected in each slot hole. The test strip cartridge is magnetically attracted to the magnet block.

[0012] For further specific optimization, the test strip lifting mechanism includes a servo stepping motor, a lead screw nut for driving the test strip carrier to lift and lower, and a vertically arranged lifting lead screw. The servo stepping motor is fixedly connected to the inner bottom of the housing. The lifting lead screw is coaxially fixedly connected to the output shaft of the servo stepping motor. The lead screw nut is rotatably connected to the lifting lead screw, and the test strip carrier is fixedly connected to the lead screw nut. The servo stepping motor is electrically connected to the main controller.

[0013] For further specific optimization, carrier rails are respectively fixedly connected to the two side walls of the test strip carrier. A test strip holder base is slidably connected to each carrier rail. Each test strip holder base is provided with a carrier chute adapted to the corresponding carrier rail, and the carrier rail is slidably connected in the corresponding carrier chute.

[0014] For further specific optimization, a test strip insertion opening is provided above the housing. The test strip carrier is slidably connected at the test strip insertion opening, and an upwardly flipping cover plate is rotatably connected to the edge of the test strip insertion opening.

[0015] Due to the adoption of the above technical solutions, compared with the prior art, the advantages of the present utility model are as follows:

[0016] The present utility model discloses a pre-treatment incubation fluorescence analyzer. When in use, a sample is placed on the sample placement rack. The side shift motor and the side shift synchronous belt cooperate to drive the sample placement rack to enter the interior from the side of the fluorescence analyzer. Then, the servo stepping motor and the lifting lead screw drive the test strip carrier connected to the lead screw nut to rise and fall, so as to bring the test strip inserted into the test strip cartridge through the test strip insertion opening into the interior of the fluorescence analyzer to react with the laterally introduced sample. At the same time, the electric heating plate and the temperature sensor can ensure that the test strip is in a constant temperature state most suitable for improving the reaction rate during the reaction, so that the biological reaction or chemical reaction is accelerated and more sufficient, the reaction linearity is more stable. After the reaction is completed, the detection motor and the detection transmission belt are used to cooperate to drive the detection head to move, and the moving distance of the detection head is sensed by the distance sensor, and the detection results of the test strip are read in sequence, greatly shortening the time for experimental operation detection and improving the work efficiency.

[0017] The present utility model will be further described below in conjunction with the accompanying drawings and specific embodiments. Description of the Drawings

[0018] Figure 1 is a schematic diagram of the overall structure of an embodiment of the present utility model.

[0019] Figure 2 is a schematic diagram of the internal structure of an embodiment of the present utility model with the outer shell removed.

[0020] Figure 3 is a schematic diagram of a partial internal structure of an embodiment of the present utility model.

[0021] Figure 4 is a schematic diagram of the structure of the side shift motor, side shift synchronous belt and tension adjustment assembly of an embodiment of the present utility model.

[0022] Figure 5 is a schematic diagram of the structure of the test strip carrier and test strip lifting mechanism of an embodiment of the present utility model.

[0023] Figure 6 is a schematic diagram of the structure of the cartridge slot and magnet block of an embodiment of the present utility model.

[0024] Figure 7 is a schematic cross-sectional structure diagram of the test strip cover plate and the electric heating plate of an embodiment of the present utility model.

[0025] Markings in the figure: 1. Outer shell; 2. Total controller; 3. Display; 4. Detection head; 41. Detection motor; 42. Detection transmission belt; 43. Detection fixing clip; 44. Detection fixing frame; 5. Test strip carrier; 51. Test strip cartridge; 52. Test strip cover plate; 53. Servo stepping motor; 54. Lead screw nut; 55. Lifting lead screw; 56. Carrier slide rail; 57. Test strip holder seat; 6. Electric heating plate; 7. Temperature sensor; 8. Distance sensor; 9. Specimen placement rack; 91. Side shift motor; 92. Side shift synchronous belt; 93. Specimen synchronous clip; 94. Tension adjustment wheel; 95. Tension fixing wheel; 96. Roller fixing frame; 97. Main transmission wheel; 98. Sub-transmission wheel; 10. Cartridge slot; 101. Slot hole; 102; Magnet block; 11. Upper flip cover plate; 111. Test strip insertion opening. Specific Embodiments

[0026] In order to clearly and completely describe the purpose and technical solution of the present utility model, and make its advantages more clearly understood, the following further details the embodiments of the present utility model with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are part of the embodiments of the present utility model, rather than all of them, and are only used to explain the embodiments of the present utility model, not to limit the embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present utility model.

[0027] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "middle", "upper", "lower", "left", "right", "inner", "outer", "top", "bottom", "side", "vertical", "horizontal", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present utility model. In addition, the terms "one", "first", "second", "third", "fourth", "fifth", "sixth" are only used for descriptive purposes and should not be construed as indicating or implying relative importance.

[0028] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the terms "installation", "connection", and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.

[0029] For the sake of simplicity and illustration, the principles of the embodiments are mainly described by referring to examples. In the following description, many specific details are set forth to provide a thorough understanding of the embodiments. However, it is obvious that for those of ordinary skill in the art, these embodiments may not be limited to these specific details in practice. In some instances, well-known methods and structures are not described in detail to avoid unnecessarily obscuring these embodiments. Additionally, all embodiments can be used in combination with each other.

[0030] Embodiment:

[0031] A pretreatment incubation fluorescence instrument comprises a shell 1, a main controller 2, a display 3 and a detection head 4 for detecting the test results of a test paper, the display 3 is embedded in the shell 1, the main controller 2 and the detection head 4 are both arranged in the shell 1, the detection head 4 and the display 3 are both electrically connected to the main controller 2, and is characterized in that: a test paper carrier 5 and a test paper lifting mechanism for lifting the test paper carrier 5 are arranged in the shell 1, the test paper lifting mechanism is connected to the inner bottom surface of the shell 1, the test paper carrier 5 is fixedly connected to the test paper lifting mechanism, a plurality of test paper card shells 51 for inserting test papers are movably connected to the test paper carrier 5, a test paper cover plate 52 is bolted to the test paper carrier 5, an electric heating plate 6 is fixedly connected to the test paper cover plate 52 close to the test paper carrier 5, a plurality of temperature sensors 7 are arranged on the side wall of the test paper carrier 5, and a detection A fixed frame 44 is provided with a detection transmission assembly for driving the detection head 4 to move. The detection head 4 is located on the side of the detection cover away from the test paper carrier 5. A distance sensor 8 is fixedly connected to the detection head 4. A sample placement frame 9, a side shift motor 91, a side shift synchronous belt 92, a synchronous transmission assembly and a tension adjustment assembly for adjusting the tension of the side shift synchronous belt 92 are also provided in the shell 1. The side shift motor 91 is fixedly arranged in the shell 1. The synchronous transmission assembly is connected to the side shift motor 91. The side shift synchronous belt 92 is driven to rotate by the synchronous transmission assembly. A sample synchronous clamp 93 is fixedly connected to the sample placement frame 9. The sample synchronous clamp 93 is clamped on the side shift synchronous belt 92. The distance sensor 8, the detection transmission assembly, the test paper lifting mechanism and the side shift motor 91 are all electrically connected to the main controller 2. The tensioning adjustment component is arranged on one side of the side shifting motor 91 close to the side shifting synchronous belt 92 and is mounted on the side shifting synchronous belt 92. After working for a period of time, the side shifting synchronous belt 92 is stretched and loosened, and is prone to slipping. The tensioning adjustment component must be used to readjust the tension to ensure the speed of the sample entering and exiting sideways.

[0032] Through the above technical solution, the test strip cover plate 52 is connected to the test strip carrier 5. The total controller 2 controls the test strip lifting mechanism to drive the test strip carrier 5 to extend out of the housing 1, and controls the side shift motor 91 to drive the synchronous transmission component to drive the side shift synchronous belt 92 and the specimen synchronous clamp 93 clamped on the side shift synchronous belt 92 to move horizontally, thereby driving the specimen placement rack 9 out of the housing 1. Insert the test strip into the test strip cartridge 51, and then place the specimen on the specimen placement rack 9. Move the placed test strip and specimen to the designated position through the test strip lifting mechanism, the side shift motor 91 and the side shift synchronous belt 92, so that the test strip is completely immersed in the specimen for reaction. The specimen enters directly from the side, avoiding replacing and placing the specimen by repeatedly opening and closing the housing 1, improving the operation convenience and shortening the incubation process time. The electric heater and the temperature sensor 7 are used in combination to ensure that the test strip is in the most suitable constant temperature state for improving the reaction rate during the reaction, so that the biological reaction or chemical reaction is accelerated and more sufficient, and the reaction linearity is more stable. After the reaction acceleration is completed, the total controller 2 controls the detection transmission component to drive the detection head 4 to move, and controls the movement and positioning of the detection head 4 through the distance sensor 8, and sequentially detects each test strip. During the detection, the test strip lifting mechanism drives the test strip to move up and down, so that the detection head 4 can detect the reaction result of the test strip without omission, improving the detection accuracy and thus improving the work efficiency.

[0033] The synchronous transmission component includes a main transmission wheel 97 and two sub-transmission wheels 98. The main transmission wheel 97 is sleeved on the output end of the side shift motor 91. The two sub-transmission wheels 98 are rotatably connected to the inner bottom of the housing 1. The main transmission wheel 97 and the two sub-transmission wheels 98 are both rotatably connected to the inner side of the side shift synchronous belt 92 and are arranged in parallel. The two sub-transmission wheels 98 are on the same horizontal line. The main transmission wheel 97 is located between the two sub-transmission wheels 98 and is higher than the two sub-transmission wheels 98. By controlling the side shift motor 91 to start through the total controller 2, the main transmission wheel 97 is driven to rotate and drives the side shift synchronous belt 92 to rotate with the cooperation of the two sub-transmission wheels 98, so that the specimen placement rack 9 is driven to move in and out laterally by the specimen synchronous clamp 93 clamped on the side shift synchronous belt 92, facilitating the placement and replacement of the specimen during incubation and detection and improving the work efficiency.

[0034] The tension adjustment assembly includes a tension adjustment wheel 94, a tension fixing wheel 95 and a roller fixing bracket 96. The roller fixing bracket 96 is fixedly connected to the side shift motor 91. The tension adjustment wheel 94 and the tension fixing wheel 95 are respectively located on both sides of the main drive wheel 97. The tension adjustment wheel 94 and the tension fixing wheel 95 are rotatably connected to the outer side of the side shift synchronous belt 92. The tension fixing wheel 95 is rotatably connected to the roller fixing bracket 96. A driving block is rotatably connected to the tension adjustment wheel 94, and the driving block is bolted to the roller fixing bracket 96. A slot hole 101 for position adjustment and a corresponding threaded hole are provided on the roller fixing bracket 96. After working for a period of time, the side shift synchronous belt 92 is stretched and loosened, and it is easy to slip. The tension must be readjusted through the tension adjustment assembly. At this time, the bolt fixing the driving block needs to be loosened, and the position of the tension adjustment wheel 94 is readjusted according to the situation of the side shift synchronous belt 92. After adjustment, the driving block is fixed again. By adjusting the tension, it is ensured that the side shift synchronous belt 92 always remains taut, so as to ensure the speed of the specimen entering and exiting from the side.

[0035] The detection drive assembly includes a detection motor 41 and a detection transmission belt 42. The detection motor 41 is fixedly connected to the detection fixing bracket 44. The detection motor 41 drives the detection transmission belt 42 to rotate. A detection fixing clip 43 is clamped on the detection transmission belt 42. The detection head 4 is fixedly connected to the detection fixing clip 43. The detection motor 41 is electrically connected to the total controller 2. When it is necessary to detect the reaction result after the reaction is completed, the total controller 2 controls the detection motor 41 to drive the detection transmission belt 42 to rotate. The rotation of the detection transmission belt 42 drives the detection fixing clip 43 and the detection head 4 fixed thereon to move. The reaction result of the test paper is sequentially read and detected by the cooperation of the detection head 4 and the distance sensor 8.

[0036] A plurality of cartridge slots 10 are provided on the test paper carrier 5. The number of temperature sensors 7 is the same as the number of cartridge slots 10 and they are correspondingly arranged in the cartridge slots 10. Each test paper cartridge 51 is correspondingly arranged in the cartridge slot 10. Two slot holes 101 are provided in each cartridge slot 10, and a magnet block 102 is fixedly connected in each slot hole 101. The test paper cartridge 51 and the magnet block 102 are magnetically attracted to each other. The iron test paper cartridge 51 is adsorbed by the magnet block 102, and the two are adsorbed and fixed magnetically, which is convenient for removing the test paper cartridge 51 to insert and place the test paper, and is also convenient for replacing the worn test paper cartridge 51, and at the same time does not affect the fixation of the test paper.

[0037] The test strip lifting mechanism includes a servo stepper motor 53, a lead screw nut 54 that drives the test strip carrier 5 to lift, and a vertically arranged lifting lead screw 55. The servo stepper motor 53 is fixedly connected to the inner bottom of the housing 1. The lifting lead screw 55 is coaxially and fixedly connected to the output shaft of the servo stepper motor 53. The lead screw nut 54 is rotatably connected to the lifting lead screw 55. The test strip carrier 5 is fixedly connected to the lead screw nut 54. The servo stepper motor 53 is electrically connected to the main controller 2. By controlling the servo stepper motor 53 through the main controller 2 to drive the lifting lead screw 55 to rotate, the lead screw nut 54 is driven to move up and down on the lifting lead screw 55, thereby driving the test strip carrier 5 to extend out of the housing 1 to place the test strip, and can also drive the test strip until the test strip reacts with the sample, and drives the test strip to move up and down when the detection head 4 performs detection after the reaction ends to identify the reaction result without omission. The servo stepper motor 53 controls all operations, simplifies the overall detection operation, and improves the detection accuracy and efficiency.

[0038] On both side walls of the test strip carrier 5, there are respectively fixedly connected with carrier slide rails 56. On each carrier slide rail 56, there is slidably connected a test strip holder seat 57. On each test strip holder seat 57, there is opened a carrier chute adapted to the corresponding carrier slide rail 56, and the carrier slide rail 56 is slidably connected in the corresponding carrier chute. Through the cooperation of the carrier slide rail 56 and the carrier chute opened on the test strip holder seat 57, the stability of the test strip carrier 5 during up and down movement is improved, the accuracy of the detection head 4 for result identification is ensured, and the detection accuracy is provided.

[0039] Above the housing 1, there is opened a test strip insertion port 111. The test strip carrier 5 is slidably connected at the test strip insertion port 111. The edge of the test strip insertion port 111 is rotatably connected with an upwardly flipping cover plate 11. Setting the upwardly flipping cover plate 11 can prevent dust from entering the interior of the fluorometer and also facilitate the insertion of the test strip, improving the convenience of operation.

[0040] When the pre-treatment incubation fluorometer is in use, the upper flip cover 11 is opened. Under the control of the main controller 2, the servo stepping motor 53 is started, driving the lifting lead screw 55 to rotate, causing the lead screw nut 54 to move on the lifting lead screw 55, driving the test strip carrier 5 to rise and extend out of the test strip insertion port 111. At the same time, the main controller 2 controls the side shift motor 91 to act. The side shift motor 91 drives the side shift synchronous belt 92 to drive the sample placement rack 9 to extend out from the side wall of the housing 1 through the sample synchronous clamp 93. Multiple samples are placed on the sample placement rack 9, and then multiple test strips are inserted into the test strip cartridge 51 in sequence. The main controller 2 then controls the servo stepping motor 53 to drive the test strip carrier 5 to descend, and at the same time controls the side shift motor 91 to act to drive the sample placement rack 9 with samples into the interior of the fluorometer until the test strip can extend into the corresponding sample for a complete reaction. When the test strip carrier 5 rises, the main controller 2 energizes and heats the electric heating plate 6. The temperature sensor 7 senses the temperature of the reaction area, maintaining the most suitable reaction temperature to accelerate and make the biological reaction or chemical reaction more sufficient, and the reaction linearity is more stable. A cooling fan is also provided inside the housing 1, and the cooling fan is also electrically connected through the main controller 2. When the temperature sensor 7 senses that the temperature of the reaction area is too high, the cooling fan starts to dissipate heat to quickly cool down to ensure a continuous constant temperature state and improve the incubation efficiency. After the reaction is completed, the detection motor 41 and the detection transmission belt 42 cooperate to drive the detection head 4 clamped on the detection transmission belt 42 through the detection fixing clamp 43 to move. The distance sensor 8 senses the moving position of the detection head 4. When the detection head 4 moves to the corresponding test strip, the servo stepping motor 53 drives it to move up and down to ensure that the detection head 4 can recognize all reaction results. Then the above operations are repeated in sequence, improving the accuracy of the detection results, greatly shortening the time for experimental operation and detection, and improving the work efficiency.

[0041] For those skilled in the art, it is obvious that the present utility model is not limited to the details of the above exemplary embodiments, and can be implemented in other specific forms without departing from the spirit or basic characteristics of the present utility model. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present utility model is defined by the appended claims rather than the above description. Therefore, all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the present utility model. Any reference signs in the claims should not be regarded as limiting the claimed rights.

[0042] In addition, it should be understood that although this specification is described according to embodiments, not every embodiment only contains an independent technical solution. This narrative way of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A pretreatment incubation fluorescence instrument, comprising a housing (1), a master controller (2), a display (3) and a detection head (4) for detecting the test result of a test strip, wherein the display (3) is embedded in the housing (1), the master controller (2) and the detection head (4) are both arranged in the housing (1), and the detection head (4) and the display (3) are both electrically connected to the master controller (2), characterized in that: A test paper carrier (5) and a test paper lifting mechanism for lifting the test paper carrier (5) are provided in the shell (1); the test paper lifting mechanism is connected to the inner bottom surface of the shell (1); the test paper carrier (5) is fixedly connected to the test paper lifting mechanism; a plurality of test paper holders (51) for inserting test papers are movably connected to the test paper carrier (5); a test paper cover plate (52) is bolted to the test paper carrier (5); a side of the test paper cover plate (52) close to the test paper carrier (5) is fixedly connected to an electric heating plate (6); a plurality of temperature sensors (7) are provided on the side wall of the test paper carrier (5); a detection fixing frame (44) is provided in the shell (1); a detection transmission assembly for driving a detection head (4) to move is fixedly connected to the detection fixing frame (44); the detection head (4) is located on a side of the detection cover plate away from the test paper carrier (5); and a detection transmission assembly (6) is fixedly connected to the detection head (4). A distance sensor (8) is provided. The housing (1) is also provided with a sample placement rack (9), a side shift motor (91), a side shift synchronous belt (92), a synchronous transmission assembly and a tension adjustment assembly for adjusting the tension of the side shift synchronous belt (92). The side shift motor (91) is fixedly arranged in the housing (1). The synchronous transmission assembly is connected to the side shift motor (91). The side shift synchronous belt (92) is driven to rotate by the synchronous transmission assembly. A sample synchronous clamp (93) is fixedly connected to the sample placement rack (9). The sample synchronous clamp (93) is clamped on the side shift synchronous belt (92). The tension adjustment assembly is arranged on a side of the side shift motor (91) close to the side shift synchronous belt (92) and is mounted on the side shift synchronous belt (92). The distance sensor (8), the detection transmission assembly, the test paper lifting mechanism and the side shift motor (91) are all electrically connected to the main controller (2).

2. The pre-treatment incubation fluorometer according to claim 1, characterized in that: The synchronous transmission assembly comprises a main transmission wheel (97) and two auxiliary transmission wheels (98); the main transmission wheel (97) is sleeved on the output end of the side shift motor (91); the two auxiliary transmission wheels (98) are rotatably connected to the inner bottom of the housing (1); the main transmission wheel (97) and the two auxiliary transmission wheels (98) are both rotatably connected to the inner side of the side shift synchronous belt (92) and are arranged in parallel; the two auxiliary transmission wheels (98) are located on the same horizontal line; the main transmission wheel (97) is located between the two auxiliary transmission wheels (98) and is arranged higher than the two auxiliary transmission wheels (98).

3. The pre-treatment incubation fluorometer according to claim 2, characterized in that: The tension adjustment assembly comprises a tension adjustment wheel (94), a tension fixing wheel (95) and a roller fixing frame (96); the roller fixing frame (96) is fixedly connected to the side shift motor (91); the tension adjustment wheel (94) and the tension fixing wheel (95) are respectively located on both sides of the main transmission wheel (97); the tension adjustment wheel (94) and the tension fixing wheel (95) are rotatably connected to the outer side of the side shift synchronous belt (92); the tension fixing wheel (95) is rotatably connected to the roller fixing frame (96); a driving block is rotatably connected to the tension adjustment wheel (94); and the driving block is bolted to the roller fixing frame (96).

4. The pre-treatment incubation fluorometer according to claim 1, characterized in that: The detection transmission assembly comprises a detection motor (41) and a detection transmission belt (42); the detection motor (41) is fixedly connected to a detection fixing frame (44); the detection motor (41) drives the detection transmission belt (42) to rotate; a detection fixing clamp (43) is clamped on the detection transmission belt (42); the detection head (4) is fixedly connected to the detection fixing clamp (43); and the detection motor (41) is electrically connected to the main controller (2).

5. The pre-treatment incubation fluorometer according to any one of claims 3 or 4, characterized in that: The test paper carrier (5) is provided with a plurality of card slots (10), the number of the temperature sensors (7) is the same as the number of the card slots (10) and they are arranged in a one-to-one correspondence in the card slots (10), the test paper card (51) is correspondingly arranged in the card slot (10), each of the card slots (10) is provided with two slot holes (101), each of the slot holes (101) is fixedly connected with a magnet block (102), and the test paper card (51) and the magnet block (102) are magnetically attracted to each other.

6. The pre-treatment incubation fluorometer according to claim 1, characterized in that: The test paper lifting mechanism comprises a servo stepper motor (53), a screw nut (54) for driving the test paper carrier (5) to lift and lower, and a vertically arranged lifting screw (55); the servo stepper motor (53) is fixedly connected to the inner bottom of the housing (1); the lifting screw (55) is coaxially fixedly connected to the output shaft of the servo stepper motor (53); the screw nut (54) is rotatably connected to the lifting screw (55); the test paper carrier (5) is fixedly connected to the screw nut (54); and the servo stepper motor (53) is electrically connected to the master controller (2).

7. The pre-treatment incubation fluorometer according to claim 1, characterized in that: The two side walls of the test paper carrier (5) are respectively fixedly connected with carrier slide rails (56), each of the carrier slide rails (56) is slidably connected with a test paper rack seat (57), each of the test paper rack seats (57) is provided with a carrier slide groove adapted to the corresponding carrier slide rail (56), and the carrier slide rail (56) is slidably connected in the corresponding carrier slide groove.

8. The pre-treatment incubation fluorometer according to claim 1, characterized in that: A test paper insertion opening (111) is provided on the upper side of the housing (1), the test paper carrier (5) is slidably connected to the test paper insertion opening (111), and an upper flip cover plate (11) is rotatably connected to the edge of the test paper insertion opening (111).

Citation Information

Patent Citations

  • Microsphere luminoscope

    CN214622323U