Drug delivery device for intracranial blood vessels

Abstract

The utility model relates to the technical field of medical instruments, and discloses a drug delivery device for intracranial blood vessels, which comprises a catheter, the catheter is composed of a front catheter, a middle catheter and a rear catheter, the middle of the middle catheter is fixedly connected with a balloon, the balloon is elliptical, balloon grooves are uniformly arranged on the outer surface of the balloon, and the balloon grooves are communicated with the front catheter and the rear catheter. A balloon groove is formed in the catheter body, the balloon groove is semicircular, a medicine coating is arranged in the balloon groove, a cavity is formed in the catheter body, the interior of the balloon is connected with the cavity through a through hole, and the through hole is circular. According to the utility model, when the balloon moves along with the catheter, the drug of the drug coating can be prevented from being dispersed in the blood vessel due to friction with the blood vessel through the balloon groove, and when the balloon reaches the position of the intracranial blood vessel needing drug application, the balloon groove protrudes outwards due to the expansion of the balloon, so that the drug coating is ejected outwards; and the whole operation is relatively convenient.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, in particular to a drug delivery device for intracranial blood vessels. Background Art

[0002] Medical devices refer to instruments, equipment, apparatus, in vitro diagnostic reagents and calibrators, materials and other similar or related items directly or indirectly used on the human body, including the required computer software. Medical devices include medical equipment and medical consumables, and their effects are mainly obtained through physical means, not through pharmacological, immunological or metabolic means, or although these means are involved but only play an auxiliary role. There are a wide variety of existing medical devices, including drug delivery devices for intracranial blood vessels.

[0003] A drug delivery device for intracranial blood vessels generally refers to a technology or device that directly delivers drugs into the brain vascular system to achieve the treatment purpose. Existing drug delivery devices for intracranial blood vessels usually use drug balloons for drug delivery. Usually, a drug coating is added to the surface of an ordinary dilation balloon. The drug coating is composed of a drug carrier and a drug, resulting in an increase in the outer diameter of the balloon, making the balloon catheter less passable in tortuous or narrow blood vessels. Moreover, due to the difference between the anatomical approach of intracranial arteries and that of coronary arteries, the path of intracranial artery blood vessels is more tortuous than that of coronary artery blood vessels, resulting in more bending required during balloon delivery and more friction with the blood vessels. When the balloon delivers drugs, the drugs on its surface will diffuse in the blood vessels due to friction with the blood vessels, resulting in a reduction in drug efficacy. Summary of the Utility Model

[0004] To make up for the above deficiencies, the utility model provides a drug delivery device for intracranial blood vessels, aiming to improve the problem that when the balloon delivers drugs, the drugs on its surface will diffuse in the blood vessels due to friction with the blood vessels, resulting in a reduction in drug efficacy.

[0005] To achieve the above object, the utility model provides the following technical solution: A drug delivery device for intracranial blood vessels includes a catheter. The catheter is composed of a front catheter, a middle catheter, and a rear catheter. A balloon is fixedly connected to the middle of the middle catheter. The outer shape of the balloon is oval. Balloon grooves are evenly arranged on the outer surface of the balloon. The outer shape of the balloon grooves is semi-circular. A drug coating is arranged inside the balloon grooves. A cavity is arranged inside the catheter. The inside of the balloon is connected to the cavity through a through hole. The outer shape of the through hole is circular.

[0006] Preferably, the outer shape of the front catheter is arc-shaped. One end of the front catheter is provided with a tip, and the tip of the front catheter has a certain curvature.

[0007] Preferably, developing rings are symmetrically and fixedly connected to the outer surfaces on both sides of the middle catheter.

[0008] Preferably, a guide wire is arranged inside the cavity, and the guide wire is matched with the catheter.

[0009] Preferably, a tube seat is fixedly connected to one side of the catheter.

[0010] Preferably, the wall thickness of the balloon is 15-25 microns, and the length range of the balloon is 5 mm-40 mm.

[0011] Preferably, the drug coating is composed of a drug carrier and a related drug.

[0012] Preferably, the length range of the catheter is 1350 cm-1450 cm.

[0013] The utility model has the following beneficial effects:

[0014] 1. In the utility model, through the balloon groove, when the balloon moves along with the catheter, it can prevent the drug of the drug coating from diffusing in the blood vessel due to friction with the blood vessel. When the balloon reaches the position where the drug is needed in the intracranial blood vessel, the balloon groove will bulge outwards due to the expansion of the balloon, so as to push the drug coating outwards. The whole operation is relatively convenient, and it solves the problem that when the balloon delivers drugs, the drugs on its surface will diffuse in the blood vessel due to friction with the blood vessel, resulting in a reduction in drug efficacy.

[0015] 2. In the utility model, by arranging a balloon groove on the surface of the balloon and arranging a drug coating inside the balloon groove, the corresponding diameter of the balloon is reduced, so that the balloon can more conveniently pass through tortuous or narrow intracranial blood vessels, thereby improving the applicability of the device. Description of the Drawings

[0016] Figure 1 is a schematic three-dimensional structure diagram of the drug delivery device for intracranial blood vessels proposed by the utility model;

[0017] Figure 2 is a schematic diagram of the balloon expansion structure of the drug delivery device for intracranial blood vessels proposed by the utility model;

[0018] Figure 3 is a schematic diagram of the internal structure of the catheter of the drug delivery device for intracranial blood vessels proposed by the utility model.

[0019] Legend Explanation:

[0020] 1. Front catheter; 2. Imaging ring; 3. Middle catheter; 4. Balloon; 5. Balloon groove; 6. Rear catheter; 7. Tube seat; 8. Catheter; 9. Drug coating; 10. Guide wire; 11. Through hole; 12. Cavity. Detailed implementation manner

[0021] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0022] Refer to Figures 1-3 , an embodiment provided by the present invention: A drug delivery device for intracranial blood vessels, including a catheter 8, which is composed of a front catheter 1, a middle catheter 3, and a rear catheter 6. A balloon 4 is fixedly connected to the middle of the middle catheter 3. The outer shape of the balloon 4 is oval. The outer surface of the balloon 4 is evenly provided with balloon grooves 5. The outer shape of the balloon grooves 5 is semicircular. A drug coating 9 is arranged inside the balloon grooves 5. A cavity 12 is arranged inside the catheter 8. The inside of the balloon 4 is connected to the cavity 12 through a through hole 11. The outer shape of the through hole 11 is circular; the outer shape of the front catheter 1 is arc-shaped. One end of the front catheter 1 is provided with a tip, and the tip of the front catheter 1 has a certain curvature; Imaging rings 2 are symmetrically and fixedly connected to the outer surfaces on both sides of the middle catheter 3; A guide wire 10 is arranged inside the cavity 12, and the guide wire 10 matches the catheter 8; A tube seat 7 is fixedly connected to one side of the catheter 8; The wall thickness of the balloon 4 is 15-25 microns, and the length range of the balloon 4 is 5 mm-40 mm; The drug coating 9 is composed of a drug carrier and related drugs; The length range of the catheter 8 is 1350 cm-1450 cm.

[0023] Specifically, through the tip of the front catheter 1, the catheter 8 is introduced into the intracranial blood vessels. The catheter 8 is guided by the guide wire 10 to move in the intracranial blood vessels. Then, the position of the balloon 4 is located through the imaging ring 2. Since the balloon groove 5 is arranged on the surface of the balloon 4, when the balloon 4 moves following the catheter 8, the drug of the drug coating 9 can be prevented from diffusing in the blood vessels due to friction with the blood vessels. When the balloon 4 reaches the position where the drug is needed in the intracranial blood vessels, liquid is injected into the interior of the balloon 4 through the cavity 12 of the catheter 8 to inflate the balloon 4. Then, due to the inflation of the balloon 4, the balloon groove 5 will bulge outwards, thereby pushing the drug coating 9 outwards to facilitate drug absorption by the intracranial blood vessels. After the drug absorption is completed, the liquid is drawn out from the cavity 12 to deflate the balloon 4, and the bulging balloon groove 5 will also return to its original position. Then, the catheter 8 and the balloon 4 are removed through the guide wire 10, thus completing the drug delivery to the intracranial blood vessels. The whole operation is relatively convenient, and it solves the problem that when the balloon delivers drugs, the drugs on its surface will diffuse in the blood vessels due to friction with the blood vessels, resulting in a reduction in drug efficacy.

[0024] Working principle: During use, through the tip of the front catheter 1, the catheter 8 is introduced into the intracranial blood vessels. The catheter 8 is guided by the guide wire 10 to move in the intracranial blood vessels. Then, the position of the balloon 4 is located through the imaging ring 2. Through the balloon groove 5, when the balloon 4 moves following the catheter 8, the drug of the drug coating 9 can be prevented from diffusing in the blood vessels due to friction with the blood vessels. When the balloon 4 reaches the position where the drug is needed in the intracranial blood vessels, liquid is injected into the interior of the balloon 4 through the cavity 12 of the catheter 8 to inflate the balloon 4. Then, due to the inflation of the balloon 4, the balloon groove 5 will bulge outwards, thereby pushing the drug coating 9 outwards to facilitate drug absorption by the intracranial blood vessels. After the drug absorption is completed, the liquid is drawn out from the cavity 12 to deflate the balloon 4, and the bulging balloon groove 5 will also return to its original position. Then, the catheter 8 and the balloon 4 are removed through the guide wire 10, thus completing the drug delivery to the intracranial blood vessels.

[0025] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A drug delivery device for intracranial blood vessels, comprising a catheter (8), characterized in that: The catheter (8) is composed of a front catheter (1), a middle catheter (3), and a rear catheter (6); a balloon (4) is fixedly connected to the middle of the middle catheter (3); the balloon (4) has an elliptical shape; balloon grooves (5) are evenly arranged on the outer surface of the balloon (4); the balloon grooves (5) have a semicircular shape; a drug coating (9) is arranged inside the balloon grooves (5); a cavity (12) is arranged inside the catheter (8); the inside of the balloon (4) is connected to the cavity (12) via a through hole (11); the through hole (11) has a circular shape.

2. The drug delivery device for intracranial blood vessels according to claim 1, characterized in that: The front conduit (1) has an arc-shaped appearance, and one end of the front conduit (1) is provided with a tip, and the tip of the front conduit (1) is provided with a certain curvature.

3. The drug delivery device for intracranial blood vessels according to claim 1, characterized in that: The outer surfaces of both sides of the middle guide tube (3) are symmetrically and fixedly connected with developing rings (2).

4. The drug delivery device for intracranial blood vessels according to claim 1, characterized in that: A guide wire (10) is arranged inside the cavity (12), and the guide wire (10) matches the catheter (8).

5. The drug delivery device for intracranial blood vessels according to claim 1, characterized in that: One side of the conduit (8) is fixedly connected to a tube seat (7).

6. The drug delivery device for intracranial blood vessels according to claim 1, characterized in that: The wall thickness of the balloon (4) is 15 to 25 micrometers, and the length of the balloon (4) is in the range of 5 to 40 millimeters.

7. The drug delivery device for intracranial blood vessels according to claim 1, characterized in that: The drug coating (9) is composed of a drug carrier and related drugs.

8. The drug delivery device for intracranial blood vessels according to claim 1, characterized in that: The length of the conduit (8) ranges from 1350 cm to 1450 cm.

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