Drug delivery device

Abstract

The utility model relates to a drug delivery device, the drug delivery device at least comprises a drug delivery unit, an anchoring unit and a drug delivery tube, and the anchoring unit is configured to be anchored in a cavity of a to-be-administered organism; the first end of the drug delivery tube is configured to be communicated with the drug delivery unit, the other end of the drug delivery tube is provided with a drug delivery through hole, and the drug delivery unit is configured to provide drugs into a cavity of a to-be-administered organism at least through the drug delivery through hole of the drug delivery tube under the condition that the anchoring unit is anchored in the cavity of the to-be-administered organism. According to the drug delivery device, the purpose of providing drugs into the cavity of the to-be-administered organism can be achieved, the anchoring unit is easy to release and firm to fix, the anchoring unit can be recycled from the cavity of the to-be-administered organism after drug delivery is completed and drug delivery does not need to be continued, the recycling difficulty is low, and the cost is low. The endothelialization reaction on the inner wall of the cavity is effectively reduced. The drug delivery device can achieve the purpose of long-term repeated drug delivery through one-time implantation, and the number of times of operations needed by a patient is reduced.

Description

Technical Field

[0001] The present disclosure relates to the field of medical treatment equipment, and more specifically, to a drug delivery device. Background Art

[0002] Fungal infections of the lungs, especially mold infections, have the following characteristics: rapid spread, requiring timely drug intervention; formation of tissue necrosis and local structural damage to the lungs in a short period of time; and rapid formation of fibrous and granulation tissue wrapping after being controlled by effective antifungal drugs or limited by the patient's own immune system.

[0003] Due to the above characteristics of pulmonary fungal infection, when treating pulmonary fungal infection, intravenous infusion of drugs may make it difficult for the drugs to exert their efficacy due to poor local blood supply. Therefore, local antifungal drugs are often used for patients with pulmonary fungal infection.

[0004] Among them, amphotericin B is a polyene antifungal drug with a broad antifungal spectrum and strong effects. When applied intravenously, the drug concentration in pleural effusion, ascites and synovial fluid is usually less than half of the blood drug concentration during the same period, and the drug concentration in bronchial secretions is even lower. The drug concentration achieved in the lungs at the commonly used therapeutic dose only has an antibacterial effect on fungi, and it is highly toxic and has many adverse reactions. However, in some cases, it is the only effective drug for the treatment of critical deep fungal infections; the drug is highly water-soluble, absorbed slowly through the airway mucosa, and has no obvious irritation to the airway mucosa.

[0005] According to the pharmacological and metabolic characteristics of amphotericin B, administration of amphotericin B through the human cavity, especially local injection into the lung through bronchoscopy, has irreplaceable advantages and is worthy of clinical promotion. However, there is currently a lack of corresponding transcavitary drug delivery devices in clinical practice. The main reason is that the catheter is difficult to fix in the human cavity, and conventional anchoring methods are not easy to locate and insert, and it is particularly difficult to remove.

[0006] Existing drug delivery technologies through artificial cavities include drug delivery through an endoscopic catheter or through percutaneous puncture. Specifically, when administering drugs locally for fungal infections in the lungs, an intrabronchial catheter is injected under the guidance of a bronchoscope, or antifungal drugs are injected percutaneously through a thoracoscopic needle or a catheter inserted into the Aspergillus lesion cavity. Generally, placing a percutaneous catheter in the lesion cavity can avoid repeated bronchoscopic operations and extend the treatment time span. However, both methods have disadvantages to varying degrees. Endoscopic drug delivery has high operational risks and high operational difficulty, and requires specially trained skilled technicians to operate; percutaneous puncture drug delivery has the risk of requiring radiation guidance such as CT, bleeding, skin damage / infection, and the introduction of exogenous skin colonization bacteria and secondary infection; more importantly, both methods cannot achieve the purpose of long-term repeated drug delivery after one-time placement. Utility Model Content

[0007] The present disclosure provides a drug delivery device to solve the problems existing in the prior art.

[0008] According to a first aspect of the present disclosure, there is provided a drug delivery device, comprising:

[0009] a drug delivery unit;

[0010] an anchoring unit configured to be anchored within a body cavity of a biological subject to be administered with a drug;

[0011] a drug delivery tube, a first end of the drug delivery tube being configured to communicate with the drug delivery unit, and the other end being provided with a drug delivery through-hole, and the drug delivery unit being configured to provide a drug into the body cavity of the biological subject to be administered with a drug at least through the drug delivery through-hole of the drug delivery tube when the anchoring unit is anchored within the body cavity of the biological subject to be administered with a drug.

[0012] In an embodiment of the present disclosure, the anchoring unit is configured to have a contracted state and an expanded state, and a radial dimension of the anchoring unit in the expanded state is greater than a radial dimension of the anchoring unit in the contracted state.

[0013] In an embodiment of the present disclosure, the anchoring unit includes a main body portion and an expansion portion, the expansion portion being sleeved outside the main body portion and being configured to be movably disposed relative to the main body portion, and the anchoring unit being configured to, when in the contracted state, contract the expansion portion onto the main body portion and, when in the expanded state, expand the expansion portion relative to the main body portion so that the expansion portion abuts against the body cavity of the biological subject to be administered with a drug.

[0014] In an embodiment of the present disclosure, a first end of the expansion portion is configured to be connected to the main body portion, a second end is configured to be freely disposed relative to the main body portion, the anchoring unit includes a restraint member, the restraint member being movably disposed along an extending direction of the main body portion and sleeved on the expansion portion, and being configured to, when the anchoring unit is in the contracted state, contract the expansion portion onto the main body portion and, when the anchoring unit is in the expanded state, move relative to the main body portion so that the expansion portion expands relative to the main body portion into an umbrella shape.

[0015] In an embodiment of the present disclosure, a first end of the expansion portion is configured to be connected to the main body portion, a second end is configured to be movably disposed on the main body portion, the anchoring unit includes a restraint member, the restraint member being movably disposed along an extending direction of the main body portion and sleeved on the expansion portion, and being configured to, when the anchoring unit is in the contracted state, contract the expansion portion onto the main body portion and, when the anchoring unit is in the expanded state, move relative to the main body portion so that the expansion portion expands relative to the main body portion into a cage shape.

[0016] In one embodiment of the present disclosure, a medicine inlet through-hole is provided at one end of the main body portion, and the medicine inlet through-hole is communicated with the medicine delivery tube;

[0017] Medicine delivery through-holes are provided on the outer wall of the main body portion and / or the outer wall of the deployment portion, and the medicine delivery through-holes on the outer wall of the main body portion and / or the outer wall of the deployment portion are communicated with the medicine inlet through-hole.

[0018] In one embodiment of the present disclosure, an antibacterial drug coating is provided on the outer surface of the deployment portion.

[0019] In one embodiment of the present disclosure, a monitoring camera unit is provided at the front end of the main body portion, and the medicine delivery device further includes a monitoring unit. The monitoring camera unit is configured to capture an image inside the cavity of the biological subject to be medicated and transmit it to the monitoring unit.

[0020] In one embodiment of the present disclosure, a heating probe and / or a freezing probe are provided at the front end of the main body portion. The heating probe is configured to heat the tissue inside the cavity of the biological subject to be medicated by increasing its own temperature, and the freezing probe is configured to freeze the tissue inside the cavity of the biological subject to be medicated by decreasing its own temperature.

[0021] In one embodiment of the present disclosure, the diameter range of the medicine delivery through-hole is 10 to 100 μm.

[0022] The present disclosure provides a medicine delivery device, which at least includes a medicine delivery unit, an anchoring unit, and a medicine delivery tube; the anchoring unit is configured to be anchored inside the cavity of the biological subject to be medicated; the first end of the medicine delivery tube is configured to be communicated with the medicine delivery unit, and the other end is provided with a medicine delivery through-hole. The medicine delivery unit is configured to provide medicine to the inside of the cavity of the biological subject to be medicated at least through the medicine delivery through-hole of the medicine delivery tube when the anchoring unit is anchored inside the cavity of the biological subject to be medicated.

[0023] In this way, during the working process of the medicine delivery device of the present disclosure, the doctor first places the anchoring unit inside the cavity of the biological subject to be medicated until the anchoring unit moves to the position to be medicated and is anchored at the position to be medicated. Then, the medicine delivery unit can pump the medicine into the medicine delivery tube. The medicine can move along the medicine delivery tube to the medicine delivery through-hole adjacent to the anchoring unit and be released from the medicine delivery through-hole. In this way, the purpose of providing medicine to the inside of the cavity of the biological subject to be medicated can be achieved. Not only is the release of the anchoring unit easy and the fixation firm, but also after the medicine delivery is completed and there is no need for continuous medicine delivery, the anchoring unit can be retrieved from the cavity of the biological subject to be medicated, and the retrieval difficulty is low, effectively reducing the endothelialization reaction occurring on the inner wall of the cavity. Moreover, compared with the existing medicine delivery devices, the medicine delivery device of the present disclosure can achieve the purpose of long-term repeated medicine delivery by one-time implantation, thereby reducing the number of surgeries required for the patient and improving the treatment effect and quality of life of the patient.

[0024] Other features and advantages of the present disclosure will become apparent from the following detailed description of exemplary embodiments of the present disclosure with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The drawings incorporated in and forming a part of this specification illustrate embodiments of the present disclosure and, together with the description, serve to explain the principles of the present disclosure.

[0026] Figure 1 is a perspective schematic view of a drug delivery device provided by an embodiment of the present disclosure;

[0027] Figure 2 is a perspective schematic view of another drug delivery device provided by an embodiment of the present disclosure;

[0028] Figures 1 to 2 The corresponding relationships between the names of the components and the reference numerals in are as follows:

[0029] 10, drug delivery unit; 20, anchoring unit; 21, main body part; 22, deployment part; 23, restraint member; 30, drug delivery tube. DETAILED DESCRIPTION

[0030] Various exemplary embodiments of the present disclosure will now be described in detail with reference to the accompanying drawings. It should be noted that: unless otherwise specifically stated, the relative arrangements of components and steps, numerical expressions and values set forth in these embodiments do not limit the scope of the present disclosure.

[0031] The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the present disclosure, its application, or uses.

[0032] Techniques, methods, and devices known to those of ordinary skill in the relevant art may not be discussed in detail, but where appropriate, such techniques, methods, and devices should be considered as part of the specification.

[0033] It should be noted that: like reference numerals and letters denote like items in the following drawings, and thus, once an item is defined in one drawing, further discussion thereof in subsequent drawings is not required.

[0034] The following describes the specific embodiments of the present disclosure with reference to the accompanying drawings.

[0035] In this document, "upper", "lower", "front", "rear", "left", "right", etc. are only used to represent the relative positional relationships between relevant parts, rather than defining the absolute positions of these relevant parts.

[0036] In this document, "first", "second", etc. are only used for distinguishing from each other, rather than indicating importance, order, and the prerequisite for each other's existence, etc.

[0037] In this text, "equal", "identical", etc. are not strict mathematical and / or geometric limitations, and also include errors that can be understood by those skilled in the art and are permitted in manufacturing or use, etc.

[0038] Unless otherwise specified, the numerical ranges in this text include not only the entire range within its two endpoints, but also several sub-ranges included therein.

[0039] The present disclosure provides a drug delivery device, which at least includes a drug delivery unit, an anchoring unit, and a drug delivery tube; the anchoring unit is configured to be anchored within a cavity of a biological subject to be administered with drugs; the first end of the drug delivery tube is configured to communicate with the drug delivery unit, the other end is provided with a drug delivery through hole, and the drug delivery unit is configured to provide drugs into the cavity of the biological subject to be administered with drugs at least through the drug delivery through hole of the drug delivery tube when the anchoring unit is anchored within the cavity of the biological subject to be administered with drugs.

[0040] Thus, during the operation of the drug delivery device of the present disclosure, a doctor first places the anchoring unit within the cavity of the biological subject to be administered with drugs until the anchoring unit moves to the position to be administered with drugs and is anchored at the position to be administered with drugs. Then, the drug delivery unit can pump the drugs into the drug delivery tube, and the drugs can move along the drug delivery tube to the drug delivery through hole adjacent to the anchoring unit and be released from the drug delivery through hole. In this way, the purpose of providing drugs into the cavity of the biological subject to be administered with drugs can be achieved. Not only is the release of the anchoring unit easy and the fixation firm, but also, after the drug administration is completed and there is no need for continuous drug administration, the anchoring unit can be retrieved from the cavity of the biological subject to be administered with drugs, and the retrieval difficulty is low, effectively reducing the endothelialization reaction occurring on the inner wall of the cavity. Moreover, compared with the existing drug delivery devices, the drug delivery device of the present disclosure can achieve the purpose of long-term repeated drug administration with a single implantation, thereby reducing the number of surgeries required for patients and improving the treatment effect and quality of life of patients.

[0041] For ease of understanding, the following refers to Figures 1 to 2 and, in combination with an embodiment, details the specific structure and working principle of the drug delivery device of the present disclosure.

[0042] As Figure 1 shown, the present disclosure provides a drug delivery device, which at least includes a drug delivery unit 10, an anchoring unit 20, and a drug delivery tube 30; the anchoring unit 20 is configured to be anchored within a cavity of a biological subject to be administered with drugs; the first end of the drug delivery tube 30 is configured to communicate with the drug delivery unit 10, the other end is provided with a drug delivery through hole, and the drug delivery unit 10 is configured to provide drugs into the cavity of the biological subject to be administered with drugs at least through the drug delivery through hole of the drug delivery tube 30 when the anchoring unit 20 is anchored within the cavity of the biological subject to be administered with drugs.

[0043] Thus, during the operation of the drug delivery device of the present disclosure, the doctor first places the anchoring unit 20 into the cavity of the biological entity to be medicated until the anchoring unit 20 moves to the position to be medicated and is anchored at the position to be medicated. Then, the drug delivery unit 10 can pump the drug into the drug delivery tube 30, and the drug can move along the drug delivery tube 30 to the drug delivery through-hole adjacent to the anchoring unit 20 and be released from the drug delivery through-hole. In this way, the purpose of providing the drug into the cavity of the biological entity to be medicated can be achieved. Not only is the release of the anchoring unit 20 easy and the fixation firm, but also after the drug delivery is completed and there is no need for continuous drug delivery, the anchoring unit 20 can be retrieved from the cavity of the biological entity to be medicated, and the retrieval difficulty is relatively low, effectively reducing the endothelialization reaction occurring on the inner wall of the cavity. Moreover, compared with the existing drug delivery devices, the drug delivery device of the present disclosure can achieve the purpose of long-term repeated drug delivery with a single implantation, thereby reducing the number of surgeries required for the patient and improving the treatment effect and quality of life of the patient.

[0044] It can be understood that the drug delivery device of the present disclosure can achieve continuous or intermittent drug delivery into the cavity of the biological entity to be medicated. Moreover, multiple drug delivery devices of the present disclosure can be used simultaneously, that is, multiple drug delivery devices of the present disclosure are implanted into the cavity of the biological entity to be medicated at the same time and are anchored at different positions in the cavity of the biological entity to be medicated, thereby increasing the local drug concentration and further improving the drug efficacy.

[0045] Furthermore, in an embodiment of the present disclosure, the anchoring unit 20 is configured to have a contracted state and an expanded state, and the radial dimension of the anchoring unit 20 in the expanded state is larger than that in the contracted state.

[0046] Thus, during the operation of the drug delivery device of the present disclosure, the doctor first places the anchoring unit 20 in the contracted state at the entrance of the cavity of the biological entity to be medicated, such as the entrance of the trachea, etc., and then makes the anchoring unit 20 continuously move along the cavity until it moves to the position to be medicated. Then, the anchoring unit 20 is converted to the expanded state, and the radial dimension continuously increases until the anchoring unit 20 abuts against the inner wall of the cavity, and then it can be anchored at the position to be medicated. Then, the operation of the drug delivery unit 10 can be controlled to deliver the drug into the cavity of the biological entity to be medicated. After the drug delivery is completed, the anchoring unit 20 can be converted to the contracted state, and the radial dimension continuously decreases until the anchoring unit 20 disengages from the inner wall of the cavity, thereby facilitating the doctor to retrieve the anchoring unit 20 from the cavity of the biological entity to be medicated.

[0047] Furthermore, as Figure 1As shown, the anchoring unit 20 includes a main body portion 21 and a deploying portion 22. The deploying portion 22 is sleeved outside the main body portion 21 and is configured to be movably arranged relative to the main body portion 21. When the anchoring unit 20 is configured to be in a contracted state, the deploying portion 22 is contracted onto the main body portion 21, and when in an expanded state, the deploying portion 22 is expanded relative to the main body portion 21 so that the deploying portion 22 abuts against the lumen of the biological organism to be administered with medicine.

[0048] Thus, during the working process of the drug delivery device of the present disclosure, before the doctor places the anchoring unit 20, it is necessary to contract the deploying portion 22 onto the main body portion 21. Then the doctor places the anchoring unit 20 in the contracted state at the entrance of the lumen of the biological organism to be administered with medicine, and makes the anchoring unit 20 continuously move along the lumen until it moves to the position to be administered with medicine. Then the deploying portion 22 can be expanded relative to the main body portion 21 so that the deploying portion 22 abuts against the lumen of the biological organism to be administered with medicine, and thus the anchoring unit 20 can be anchored at the position to be administered with medicine. After the drug administration is completed, the deploying portion 22 can be detached from the inner wall of the lumen and contracted onto the main body portion 21, thereby facilitating the doctor to recover the anchoring unit 20 from the lumen of the biological organism to be administered with medicine.

[0049] Specifically, the structure of the deploying portion 22 can be various. For example Figure 1 As shown, in an embodiment of the present disclosure, the first end of the deploying portion 22 is configured to be connected to the main body portion 21, and the second end is configured to be freely arranged relative to the main body portion 21. The anchoring unit 20 includes a binding member 23. The binding member 23 is movably arranged along the extending direction of the main body portion 21 and is sleeved on the deploying portion 22, and is configured to contract the deploying portion 22 onto the main body portion 21 when the anchoring unit 20 is in a contracted state, and move relative to the main body portion 21 when the anchoring unit 20 is in an expanded state so that the deploying portion 22 is expanded relative to the main body portion 21 into an umbrella shape.

[0050] That is, during the working process of the drug delivery device of the present disclosure, after the doctor places the anchoring unit 20 at the position to be administered with medicine, the binding member 23 can be controlled to move along the extending direction of the main body portion 21, so that the deploying portion 22 can be expanded relative to the main body portion 21 into an umbrella shape, so that the deploying portion 22 abuts against the lumen of the biological organism to be administered with medicine. Before recovering the anchoring unit 20, the binding member 23 can also be controlled to move along the extending direction of the main body portion 21 to contract the deploying portion 22 onto the main body portion 21, and then the anchoring unit 20 is recovered. The above structure can greatly reduce the difficulty of expanding and contracting the deploying portion 22, thereby making the operation of the drug delivery device of the present disclosure more convenient.

[0051] And for example Figure 2As shown, in another embodiment of the present disclosure, the first end of the deployment portion 22 is configured to be connected to the main body portion 21, and the second end is configured to be movably disposed on the main body portion 21. The anchoring unit 20 includes a restraint member 23. The restraint member 23 is movably disposed along the extending direction of the main body portion 21 and sleeved on the deployment portion 22, and is configured to cause the deployment portion 22 to contract on the main body portion 21 when the anchoring unit 20 is in a contracted state, and move relative to the main body portion 21 when the anchoring unit 20 is in an expanded state, so that the deployment portion 22 is expanded relative to the main body portion 21 into a cage shape.

[0052] That is, during the operation of the drug delivery device of the present disclosure, after the doctor places the anchoring unit 20 at the position to be medicated, the restraint member 23 can be controlled to move along the extending direction of the main body portion 21, so that the deployment portion 22 can be expanded relative to the main body portion 21 into a cage shape, so that the deployment portion 22 abuts against the cavity of the organism to be medicated. Before recovering the anchoring unit 20, the restraint member 23 can also be controlled to move along the extending direction of the main body portion 21, so that the deployment portion 22 contracts on the main body portion 21, and then the anchoring unit 20 is recovered. The above structure can greatly reduce the difficulty of expanding and contracting the deployment portion 22, thereby making the operation of the drug delivery device of the present disclosure more convenient.

[0053] It can be understood that, in order to improve the drug delivery efficiency, drugs can be delivered not only through the drug delivery through holes on the drug delivery tube 30, such as Figure 2 As shown, in an embodiment of the present disclosure, a drug inlet through hole is provided at one end of the main body portion 21, and the drug inlet through hole is communicated with the drug delivery tube 30; drug delivery through holes are provided on the outer wall of the main body portion 21 and / or the outer wall of the deployment portion 22, and the drug delivery through holes on the outer wall of the main body portion 21 and / or the outer wall of the deployment portion 22 are communicated with the drug inlet through hole.

[0054] In this way, during the operation of the drug delivery device of the present disclosure, the doctor first places the anchoring unit 20 in the cavity of the organism to be medicated until the anchoring unit 20 moves to the position to be medicated and is anchored at the position to be medicated. Then, the drug delivery unit 10 can pump the drug into the drug delivery tube 30, and the drug can move along the drug delivery tube 30 to the drug delivery through hole adjacent to the anchoring unit 20 and be released from the drug delivery through hole. In this way, the purpose of providing drugs to the cavity of the organism to be medicated can be achieved. Not only is the release of the anchoring unit 20 easy and the fixation firm, but also, after the drug delivery is completed and there is no need for continuous drug delivery, the anchoring unit 20 can be recovered from the cavity of the organism to be medicated, and the recovery difficulty is relatively low, effectively reducing the endothelialization reaction occurring on the inner wall of the cavity.

[0055] Specifically, the diameter range of the drug delivery through hole is 10 to 100 μm. In this way, it can be ensured that drug molecules can effectively pass through the drug delivery through hole and enter the patient's cavity to complete the drug delivery process.

[0056] Further, in an embodiment of the present disclosure, an antibacterial drug coating is provided on the outer surface of the deployment portion 22. In this way, during the process of the drug delivery device of the present disclosure, not only can the drug be delivered through the above-mentioned drug delivery through-holes, but also the antibacterial drug coating provided on the outer surface of the deployment portion 22 can be used for drug delivery, thereby further increasing the local drug concentration and improving the drug efficacy.

[0057] In an embodiment of the present disclosure, a monitoring camera unit is provided at the front end of the main body portion 21, and the drug delivery device further includes a monitoring unit. The monitoring camera unit is configured to capture an image of the cavity of the biological entity to be administered with the drug and transmit it to the monitoring unit. Since the monitoring camera unit can capture an image of the cavity of the biological entity to be administered with the drug and transmit it to the monitoring unit, during the operation of the drug delivery device of the present disclosure, a doctor can place the anchoring unit 20 into the cavity of the biological entity to be administered with the drug through the cavity image until the anchoring unit 20 moves to the position to be administered with the drug and is anchored at the position to be administered with the drug; during the process of retrieving from the cavity of the biological entity to be administered with the drug, the cavity image of the biological entity to be administered with the drug can also be utilized, thereby reducing the retrieval difficulty. Moreover, a doctor can also perform the diagnosis and differentiation of related diseases through the cavity image of the patient.

[0058] In an embodiment of the present disclosure, a heating probe and / or a freezing probe are provided at the front end of the main body portion 21. The heating probe is configured to heat the tissue in the cavity of the biological entity to be administered with the drug by increasing its own temperature, and the freezing probe is configured to freeze the tissue in the cavity of the biological entity to be administered with the drug by decreasing its own temperature.

[0059] Specifically, when the drug delivery device of the present disclosure penetrates into the trachea or bronchus of a patient, the heating probe can heat by increasing its own temperature, which can effectively ablate the proliferated bronchial smooth muscle cells of the patient, widen the airway, and improve the patient's dyspnea symptoms. The freezing probe can cause the intracellular and extracellular crystallization dehydration and protein denaturation of local tissue cells in the patient's trachea, resulting in local tissue ischemia and necrosis, and thus can be effectively used for the resection of malignant tumors in the trachea and the treatment of inflammatory hyperplastic lesions in the airway. It can be understood that when cryotherapy needs to be performed using liquid nitrogen or liquid carbon dioxide, the freezing probe can be connected to relevant external devices through a pipeline.

[0060] It can be seen that the drug delivery device of the present disclosure can not only administer drugs into the cavity of the biological entity to be administered with the drug, but also perform heat treatment and cryotherapy on the tissue in the cavity of the biological entity to be administered with the drug, without the need to separately use devices with heating and freezing functions for treatment, thereby effectively improving the treatment efficiency.

[0061] The embodiments of the present disclosure have been described above. The above description is exemplary and not exhaustive, and is also not limited to the disclosed embodiments. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The choice of terms used herein is intended to best explain the principles of the embodiments, the practical application, or the improvement of technologies in the market, or to enable other ordinary skill in the art to understand the embodiments disclosed herein. The scope of the present disclosure is defined by the appended claims.

Claims

1. A drug delivery device, characterized in that: include: a drug delivery unit (10); An anchoring unit (20), the anchoring unit (20) being configured to have a contracted state and an expanded state, and the radial dimension of the anchoring unit (20) in the expanded state is greater than the radial dimension in the contracted state; The anchoring unit (20) comprises a main body (21) and an expansion part (22), the expansion part (22) being sleeved outside the main body (21) and being configured to be movably arranged relative to the main body (21), the anchoring unit (20) being configured to cause the expansion part (22) to be contracted on the main body (21) when in a contracted state, and to cause the expansion part (22) to be expanded relative to the main body (21) when in the expanded state, so that the expansion part (22) abuts against a cavity of a biological being to be administered; the anchoring unit (20) being configured to be anchored in a cavity of a biological being to be administered; A drug administration tube (30), wherein a first end of the drug administration tube (30) is configured to be in communication with the drug administration unit (10), and the other end is provided with a drug administration through hole, and the drug administration unit (10) is configured to provide drugs into the cavity of the organism to be administered at least through the drug administration through hole of the drug administration tube (30) when the anchoring unit (20) is anchored in the cavity of the organism to be administered.

2. The drug delivery device according to claim 1, characterized in that: The first end of the unfolding portion (22) is configured to be connected to the main body (21), and the second end is configured to be freely arranged relative to the main body (21). The anchoring unit (20) comprises a restraining member (23), which is movably arranged along the extension direction of the main body (21) and sleeved on the unfolding portion (22), and is configured to cause the unfolding portion (22) to be retracted on the main body (21) when the anchoring unit (20) is in a retracted state, and to move relative to the main body (21) when the anchoring unit (20) is in the unfolded state, so that the unfolding portion (22) is unfolded into an umbrella shape relative to the main body (21).

3. The drug delivery device according to claim 1, characterized in that: The first end of the unfolding portion (22) is configured to be connected to the main body (21), and the second end is configured to be movably arranged on the main body (21). The anchoring unit (20) comprises a restraining member (23). The restraining member (23) is movably arranged along the extension direction of the main body (21) and sleeved on the unfolding portion (22). The restraining member (23) is configured to cause the unfolding portion (22) to be retracted on the main body (21) when the anchoring unit (20) is in a retracted state, and to move relative to the main body (21) when the anchoring unit (20) is in the unfolded state, so that the unfolding portion (22) is unfolded into a cage shape relative to the main body (21).

4. The drug delivery device according to any one of claims 1 to 3, characterized in that: One end of the main body (21) is provided with a drug inlet through hole, and the drug inlet through hole is connected to the drug delivery tube (30); A drug administration through hole is provided on the outer wall of the main body (21) and / or the outer wall of the expansion part (22), and the drug administration through hole on the outer wall of the main body (21) and / or the outer wall of the expansion part (22) is connected to the drug inlet through hole.

5. The drug delivery device according to claim 1, characterized in that: The outer surface of the unfolding portion (22) is coated with an antibacterial drug coating.

6. The drug delivery device according to claim 1, characterized in that: A monitoring camera unit is provided at the front end of the main body (21), and the drug delivery device further comprises a monitoring unit. The monitoring camera unit is configured to capture images of the cavity of the organism to be administered and transmit the images to the monitoring unit.

7. The drug delivery device according to claim 1, characterized in that: The front end of the main body (21) is provided with a heating probe and / or a freezing probe. The heating probe is configured to heat the tissue in the cavity of the organism to be administered by increasing its own temperature, and the freezing probe is configured to freeze the tissue in the cavity of the organism to be administered by lowering its own temperature.

8. The drug delivery device according to claim 1, characterized in that: The diameter of the drug delivery through hole ranges from 10 to 100 μm.

Images