Serum purification equipment

By adopting a combined structure of a suction cylinder, mounting ring and ceramic composite membrane in the serum purification equipment, the problem of impurities mixing during serum purification in the prior art is solved, and the high purity of serum and the improvement of blood centrifugal effect is achieved.

CN223009905UActive Publication Date: 2025-06-24ANHUI KANGYUAN BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422010485.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-19
Publication Date
2025-06-24
Estimated Expiration
2034-08-19

AI Technical Summary

Technical Problem

The existing serum purification device easily aspirates the impurities in the lower layer when suctioning high-purity serum, resulting in the inability to guarantee the serum purity.

Method used

A serum purification equipment is designed, using a combined structure of a suction cylinder, a mounting ring and a ceramic composite film. The ceramic composite film laid in the mounting ring is separated from the lower impurities, so that the suction hole at the bottom of the suction cylinder avoids impurities when suctioning high-purity serum.

Benefits of technology

It effectively avoids the inclusion of impurities, ensures the high purity of the serum, and improves the blood centrifugation effect by reducing friction, and has a good overall use effect.

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Abstract

The utility model provides serum purification equipment and belongs to the technical field of biological scientific research. Comprising a base, a rotatable rotating disc is rotationally installed in the middle of the upper end face of the base, a rotating cylinder is fixed to the rotating disc, a fixing frame is fixed to one end of the base, the top of the fixing frame extends to the position over the rotating cylinder, and a vertical screw rod is inserted into the top of the fixing frame in a threaded mode, and a suction cylinder used for extending into the rotating cylinder is rotationally installed at the lower end of the screw rod; a suction pipe is connected to one side of the top of the suction cylinder, a mounting ring matched with the inner diameter of the rotating cylinder is rotationally mounted at the bottom of the suction cylinder, a ceramic composite film is laid in the mounting ring, and a suction hole is formed in one side of the bottom of the suction cylinder and located above the mounting ring. According to the utility model, the lower layer of blood can be separated when upper layer serum is sucked, so that impurities are prevented from being mixed in, the purity of the serum can be effectively ensured, and the blood centrifugal effect can be further improved through the arrangement of a friction reducing structure, so that the whole use effect is good.
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Description

Technical Field

[0001] The utility model relates to the technical field of biological scientific research, in particular to a serum purification device. Background Technique

[0002] Bovine serum is the natural culture medium with the largest consumption in cell culture. It contains rich nutritional components essential for cell growth, can provide hormones for maintaining exponential cell growth, nutrients that are absent or in small amounts in the basal medium, and mainly low-molecular-weight nutrients. It is commonly used for in vitro culture of animal cells and has extremely important functions.

[0003] At present, for the existing bovine serum purification device, a Chinese patent with the publication number CN211141933U discloses a bovine serum purification device, including a base. A rotation driving mechanism is provided at the bottom end of the base, and a rotating cylinder is rotatably connected to the center of the top end of the base. A fixed sleeve is sleeved and rotatably connected to the middle part outside the rotating cylinder. A fixed support is fixedly connected between the bottom end of the fixed sleeve and the base. A fixed rod is fixedly connected to the top end of the fixed sleeve, and a top seat is fixedly connected to the top end of the fixed rod. The rotating cylinder is coaxially rotatably connected to a fixed pipe, and a suction mechanism is provided on the fixed pipe. A delivery pump is fixedly connected to the top end of the top seat, and an external delivery pipe is fixedly connected between the input end of the delivery pump and the fixed pipe. The suction mechanism includes an internal absorption pipe arranged in the fixed pipe. This utility model can centrifuge bovine blood through the rotation driving mechanism and rotation to obtain the upper-layer bovine serum, and then suck it according to the layer with high serum purity through the suction mechanism, so that the prepared serum has high purity.

[0004] However, in actual use of this existing technology, during the process of sucking by extending into the high-purity serum layer, impurities in the lower layer may still be sucked up. Therefore, the high purity of the serum cannot be guaranteed, and the use effect still needs to be further optimized.

[0005] Therefore, this application provides a serum purification device to solve the above technical problems. Summary of the Utility Model

[0006] The technical problem to be solved by the utility model is to provide a serum purification device to solve the problem that the existing serum purification device is likely to suck out impurities in the lower layer and cannot guarantee the purity of the serum.

[0007] To solve the above technical problems, the utility model provides the following technical solutions:

[0008] A serum purification device, including a base, a rotatable turntable is rotatably installed in the middle of the upper end surface of the base, a rotating cylinder is fixed on the turntable, and a fixed frame is fixed at one end of the base. The top of the fixed frame extends directly above the rotating cylinder and is threadedly inserted with a vertical screw rod. The lower end of the screw rod is rotatably installed with a suction cylinder for extending into the rotating cylinder. One side of the top of the suction cylinder is connected with a suction pipe. The bottom of the suction cylinder is rotatably installed with an installation ring adapted to the inner diameter of the rotating cylinder. A ceramic composite membrane is laid in the installation ring. A suction hole is opened on one side of the bottom of the suction cylinder, and the suction hole is located above the installation ring.

[0009] Optionally, a screw hole for the vertical penetration of the screw rod is opened at the top of the fixed frame. The top end of the screw rod is located above the fixed frame and is fixed with a screwing cap.

[0010] Optionally, a vertical limit sliding groove is opened at the outer edge of the installation ring, and a vertical limit rib is constructed on the inner wall of the rotating cylinder. The limit rib is in vertical sliding fit with the limit sliding groove.

[0011] Optionally, a discharge pipe is installed at the bottom of the rotating cylinder. A valve is installed on the discharge pipe, and a liquid level window is arranged on the side of the rotating cylinder.

[0012] Optionally, a limit ring is fixed in the middle of the lower end surface of the turntable, and a plurality of balls are fitted and installed on the lower end surface of the limit ring.

[0013] Optionally, a motor is fitted in the middle of the lower end surface of the turntable. The motor is fixed in the base, and the motor shaft is fixed at the center point of the lower end surface of the turntable.

[0014] Optionally, the suction pipe is connected with a delivery pump, and the delivery pump is installed on the side of the fixed frame.

[0015] Compared with the prior art, the present utility model has at least the following beneficial effects:

[0016] In the above solution, thanks to the cooperation of the suction cylinder, the installation ring and the ceramic composite membrane, when the lower end of the suction cylinder is extended to the position of the high-purity serum layer in the rotating cylinder, the ceramic composite membrane laid in the installation ring can be used to separate from the impurities in the lower layer, so that when the suction hole at the bottom of the suction cylinder sucks the high-purity serum, impurities can be effectively avoided from mixing in, thus ensuring the serum purity and having a good use effect.

[0017] At the same time, thanks to the setting of the limit ring and the balls on the lower end surface of the turntable, the friction can be reduced by using the balls, so that when the motor drives the turntable to drive the rotating cylinder to perform a rotating centrifugation operation, it is smoother and conducive to ensuring the centrifugation effect.

[0018] In summary, the present device can separate the lower layer of blood when aspirating the upper layer of serum to avoid the mixing of impurities, thereby effectively ensuring the purity of the serum. Moreover, through the structural arrangement for reducing friction, the centrifugation effect of the blood can be further improved, and the overall use effect is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The drawings incorporated herein and constituting a part of the specification illustrate embodiments of the present utility model and, together with the specification, are further used to explain the principles of the present utility model and enable those skilled in the relevant art to implement and use the present utility model.

[0020] Figure 1 It is a schematic structural diagram of a serum purification device;

[0021] Figure 2 It is a schematic structural diagram of a suction cylinder;

[0022] Figure 3 is Figure 1 an enlarged schematic diagram of the structure at A in

[0023] Figure 4 It is a schematic diagram of the bottom structure of a rotating disk.

[0024] [Reference Numerals]

[0025] 1, base; 2, rotating disk; 201, limiting ring; 202, ball; 203, motor; 3, rotating cylinder; 301, discharge pipe; 302, liquid level window; 303, limiting rib; 4, fixing frame; 5, screw; 6, suction cylinder; 601, suction hole; 7, suction pipe; 701, delivery pump; 8, mounting ring; 801, limiting chute; 9, ceramic composite membrane.

[0026] As shown in the figure, in order to clearly implement the structure of the embodiments of the present utility model, specific structures and devices are marked in the figure, but this is only for schematic purposes and is not intended to limit the present utility model to this specific structure, device and environment. According to specific needs, those of ordinary skill in the art can adjust or modify these devices and environments. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0027] The following describes in detail a serum purification device provided by the present utility model in conjunction with the drawings and specific embodiments. At the same time, it should be noted here that in order to make the embodiments more detailed, the following embodiments are the best and preferred embodiments. For some well-known technologies, those skilled in the art can also adopt other alternative methods for implementation; moreover, the drawing part is only for more specifically describing the embodiments and is not intended to specifically limit the present utility model.

[0028] It should be noted that the references to "one embodiment", "an embodiment", "an exemplary embodiment", "some embodiments" and the like in the specification indicate that the embodiments described may include specific features, structures or characteristics, but not every embodiment may include the specific features, structures or characteristics. In addition, when a specific feature, structure or characteristic is described in conjunction with an embodiment, it should be within the knowledge of a person skilled in the art to implement such feature, structure or characteristic in conjunction with other embodiments (whether or not explicitly described).

[0029] In general, a term can be understood, at least in part, from its use in context. For example, depending, at least in part, on the context, the term "one or more" as used herein can be used to describe any feature, structure, or characteristic in the singular sense, or can be used to describe a combination of features, structures, or characteristics in the plural sense. Additionally, the term "based on" can be understood as not necessarily intended to convey an exclusive set of factors, but can instead, depending, at least in part, on the context, allow for the presence of other factors that are not necessarily explicitly described.

[0030] It is to be understood that the meanings of “on,” “over,” and “above” in the present invention should be interpreted in the broadest manner, so that “on” not only means “directly on” something, but also includes the meaning of being “on” something with intervening features or layers, and “on” or “above” not only means “on” or “above” something, but also includes the meaning of being “on” or “above” something with no intervening features or layers.

[0031] Additionally, spatially relative terms such as "under," "beneath," "lower," "above," "upper," and the like may be used herein for descriptive convenience to describe the relationship of one element or feature to another element or features, as shown in the accompanying drawings. Spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the accompanying drawings. The device may be oriented in other ways, and the spatially relative descriptors used herein may be similarly interpreted accordingly.

[0032] like Figure 1 and Figure 2 As shown, an embodiment of the utility model provides a serum purification device, including a base 1, a rotatable rotating disk 2 is rotatably installed in the middle of the upper end surface of the base 1, a rotating drum 3 is fixed on the rotating disk 2, and a fixing frame 4 is fixed at one end of the base 1, the top of the fixing frame 4 extends to the top of the rotating drum 3, and a vertical screw 5 is threadedly inserted, and a screw hole for the screw 5 to vertically pass through is opened at the top of the fixing frame 4, the top of the screw 5 is located above the fixing frame 4, and a screw cap is fixed, so that the rotatable screw 5 can be vertically lifted and lowered directly above the rotating drum 3.

[0033] The lower end of the screw 5 is rotatably installed with a suction cylinder 6 for extending into the rotating cylinder 3. A suction tube 7 is connected to one side of the top of the suction cylinder 6. The suction tube 7 is connected to the interior of the suction cylinder 6, and the suction tube 7 is connected to a delivery pump 701. The delivery pump 701 is installed on the side of the fixed frame 4. The delivery pump 701 and the suction tube 7 can cooperate with the suction cylinder 6 to suck serum.

[0034] At the same time, a mounting ring 8 adapted to the inner diameter of the rotating drum 3 is rotatably mounted at the bottom of the suction cylinder 6, a ceramic composite membrane 9 is laid inside the mounting ring 8, and a suction hole 601 is opened on one side of the bottom of the suction cylinder 6, and the suction hole 601 is located above the mounting ring 8. Therefore, the suction cylinder 6 can drive the mounting ring 8 to extend into the rotating drum 3, so as to facilitate the ceramic composite membrane 9 to separate impurities in the lower layer of blood to prevent impurities from mixing into the upper layer of serum.

[0035] In specific implementation, Figure 3 As shown, a vertical limiting groove 801 is provided on the outer edge of the mounting ring 8, and a vertical limiting ridge 303 is constructed on the inner wall of the rotating drum 3. The limiting ridge 303 vertically slides with the limiting groove 801, so that the mounting ring 8 can be stably lifted and lowered vertically in the rotating drum 3.

[0036] like Figure 1 and Figure 4 As shown, a limiting ring 201 is fixed in the middle of the lower end surface of the rotating disk 2, and a plurality of balls 202 are embedded and installed on the lower end surface of the limiting ring 201, and a motor 203 is matched in the middle of the lower end surface of the rotating disk 2, and the motor 203 is fixed in the base 1, and the shaft of the motor 203 is fixed at the center point of the lower end surface of the rotating disk 2. Therefore, the rotating disk 2 and the drum 3 can be driven to rotate by the motor 203 to perform blood centrifugation, and the setting of the balls 202 can reduce friction and effectively maintain the smoothness of centrifugal rotation, and the use effect is good.

[0037] In addition, in this embodiment, a discharge pipe 301 is installed at the bottom of the rotating drum 3 , a valve is installed on the discharge pipe 301 , and a liquid level window 302 is provided on the side of the rotating drum 3 .

[0038] The working principle provided by the present utility model for this serum purification device is as follows. When in use, blood can be placed in the rotating drum 3. By starting the motor 203, the rotating disk 2 is controlled to drive the rotating drum 3 to rotate, thereby centrifuging the blood. After the centrifugation process, the screw 5 can be rotated to drive the suction cylinder 6 to descend and extend to the position of the high-purity serum layer in the rotating drum 3. The ceramic composite membrane 9 laid in the mounting ring 8 is used to separate the impurities in the lower layer, so that when the suction holes 601 at the bottom of the suction cylinder 6 suck the high-purity serum, impurities can be effectively prevented from mixing in, thus ensuring the purity of the serum and having a good use effect.

[0039] In summary, this device can separate the lower layer of blood when sucking the upper-layer serum to avoid the mixing of impurities, thereby effectively ensuring the purity of the serum. Moreover, through the structural setting for reducing friction, the blood centrifugation effect can be further improved, and the overall use effect is good.

[0040] The present utility model covers any substitutions, modifications, equivalent methods, and solutions made on the essence and scope of the present utility model. To enable the public to have a thorough understanding of the present utility model, specific details are described in detail in the following preferred embodiments of the present utility model. However, those skilled in the art can fully understand the present utility model without the description of these details. Additionally, to avoid unnecessary confusion to the essence of the present utility model, well-known methods, processes, procedures, components, and circuits are not described in detail.

[0041] The above description is only a preferred embodiment of the present utility model. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present utility model, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present utility model.

Claims

1. A serum purification device, comprising a base (1), characterized in that: A rotatable rotating disk (2) is rotatably mounted on the middle part of the upper end surface of the base (1), a rotating drum (3) is fixed on the rotating disk (2), and a fixing frame (4) is fixed on one end of the base (1), the top of the fixing frame (4) extends to the top of the rotating drum (3), and a vertical screw (5) is threadedly inserted, and a suction cylinder (6) for extending into the rotating drum (3) is rotatably mounted on the lower end of the screw (5), a suction tube (7) is connected to one side of the top of the suction cylinder (6), and a mounting ring (8) adapted to the inner diameter of the rotating drum (3) is rotatably mounted on the bottom of the suction cylinder (6), a ceramic composite membrane (9) is laid in the mounting ring (8), and a suction hole (601) is opened on one side of the bottom of the suction cylinder (6), and the suction hole (601) is located above the mounting ring (8).

2. The serum purification device according to claim 1, characterized in that: The top of the fixing frame (4) is provided with a screw hole for the screw rod (5) to vertically penetrate; the top end of the screw rod (5) is located above the fixing frame (4) and is fixed with a screw cap.

3. The serum purification device according to claim 1, characterized in that: A vertical limiting sliding groove (801) is provided on the outer edge of the mounting ring (8), and a vertical limiting ridge (303) is constructed on the inner wall of the rotating drum (3), and the limiting ridge (303) is vertically slidably matched with the limiting sliding groove (801).

4. The serum purification device according to claim 1, characterized in that: A discharge pipe (301) is installed at the bottom of the rotating drum (3), a valve is installed on the discharge pipe (301), and a liquid level window (302) is arranged on the side of the rotating drum (3).

5. The serum purification device according to claim 1, characterized in that: A limiting ring (201) is fixed to the middle of the lower end surface of the rotating disk (2), and a plurality of balls (202) are embedded and mounted on the lower end surface of the limiting ring (201).

6. The serum purification device according to claim 5, characterized in that: A motor (203) is provided in the middle of the lower end surface of the rotating disk (2); the motor (203) is fixed in the base (1); and the shaft of the motor (203) is fixed to the center point of the lower end surface of the rotating disk (2).

7. The serum purification device according to claim 1, characterized in that: The suction pipe (7) is connected to a delivery pump (701), and the delivery pump (701) is installed on the side of the fixing frame (4).

Citation Information

Patent Citations

  • Bovine serum purification equipment

    CN211141933U