Pulverizer for producing ursodesoxycholic acid preparation

Abstract

The utility model discloses a pulverizer for ursodesoxycholic acid preparation production, which comprises a pulverizing cylinder, the center of the rear end of the pulverizing cylinder is communicated with a connecting pipe, the upper end of the connecting pipe is communicated with a hopper, the lower end of the pulverizing cylinder is fixedly connected with a collecting box, and four corners of the lower end of the collecting box are fixedly connected with supporting legs. A limiting frame is fixedly connected to the interior of the front end of the connecting pipe, a two-stage crushing system comprising first-stage crushing and second-stage crushing is designed, stage-by-stage crushing of an ursodesoxycholic acid raw material is achieved through configuration of different crushing rolling plates and filtering holes, the crushing efficiency and the powder fineness are improved, and the crushing efficiency is improved. Extrusion balls are introduced into a gap between the first-stage crushing rolling plate and the second-stage crushing rolling plate, the crushing strength of raw materials is enhanced through the rolling effect of the balls, the crushing quality and efficiency are improved, a gear transmission system is arranged between the crushing rotating shaft and the crushing filter cylinder, reverse rotation of the crushing filter cylinder and the crushing rolling plates is achieved, and the crushing efficiency is improved. And uniform distribution and efficient crushing of the raw materials in the crushing process are facilitated.

Description

Technical Field

[0001] The utility model belongs to the technical field related to pulverizers, and particularly relates to a pulverizer for the production of ursodeoxycholic acid preparations. Background Art

[0002] In the pharmaceutical industry, ursodeoxycholic acid, as an important pharmaceutical ingredient, is widely used in the treatment of various liver and gall diseases. To meet the requirements of preparation production, the raw material of ursodeoxycholic acid needs to be finely pulverized to achieve specific particle sizes and uniformity. Traditional pulverizing equipment usually adopts a single-level pulverizing mechanism, which has problems such as low pulverizing efficiency and uneven particle sizes, seriously affecting the quality and production efficiency of the preparations.

[0003] In addition, traditional pulverizing equipment often lacks an effective raw material mixing and dispersion mechanism, resulting in uneven distribution of the raw materials during the pulverizing process and affecting the pulverizing effect. Moreover, the pulverizing and collection processes of traditional equipment are separated, increasing the operation complexity and production cost.

[0004] In view of the above problems, this patent proposes a new type of ursodeoxycholic acid pulverizer, which adopts a number of innovative technologies such as a two-stage pulverizing system, extrusion ball-assisted pulverization, reverse rotation mechanism, classification and filtration design, integrated pulverizing and collection, and automatic control, effectively solving the deficiencies of the prior art, improving the pulverizing efficiency and product quality, reducing the production cost, and providing an efficient and stable solution for the production of ursodeoxycholic acid preparations. Summary of the Utility Model

[0005] The purpose of the utility model is to provide a pulverizer for the production of ursodeoxycholic acid preparations, so as to solve the problems of low pulverizing efficiency and uneven particle sizes existing in the traditional pulverizing equipment with a single-level pulverizing mechanism as mentioned in the above background art.

[0006] To achieve the above object, the present utility model provides the following technical solutions: A crusher for the production of ursodeoxycholic acid preparations, comprising a crushing cylinder, a connecting pipe is communicated at the center of the rear end of the crushing cylinder, a hopper is communicated at the upper end of the connecting pipe, a collection box is fixedly connected to the lower end of the crushing cylinder, support legs are fixedly connected to the four corners of the lower end of the collection box, a limiting frame is fixedly connected to the inner part of the front end of the connecting pipe, a limiting connection cover with an opening facing forward is fixedly connected to the inner part of the front end of the crushing cylinder, a fixing frame is fixedly connected to the inner part of the front end of the limiting connection cover, a crushing rotating shaft is rotatably connected to the inner part of the front end of the limiting frame, and the front ends of the crushing rotating shafts all penetrate through the inner parts of the centers of the limiting connection cover and the fixing frame from front to back. A plurality of primary crushing roller plates are fixedly connected to the outer rear side of the crushing rotating shaft, a crushing motor is arranged at the front end of the crushing rotating shaft, and the front end of the crushing rotating shaft is rotatably connected to the inner part of the rear end center of the crushing motor. The crushing motor is fixedly connected to the front end of the fixing frame. A crushing filter cylinder is rotatably connected between the inner walls of the front and rear ends of the crushing cylinder through two limiting rotating rings, and the two limiting rotating rings are respectively fixedly connected to the outer sides of the centers of the inner walls of the front and rear ends of the crushing cylinder. The crushing filter cylinder is sleeved outside a plurality of primary crushing roller plates, and the front end of the crushing filter cylinder is sleeved outside the limiting connection cover. A plurality of primary filter holes are opened in the cylindrical outer wall of the crushing filter cylinder.

[0007] Preferably, a tooth groove is opened in the inner part of the front side of the cylindrical inner wall of the crushing filter cylinder, and a driven gear is rotatably connected to the inner part of the lower end of the tooth groove.

[0008] Preferably, a driving gear is rotatably connected to the upper end of the driven gear, and the driving gear is fixedly connected to the outer part of the crushing rotating shaft. The driving gear is rotatably connected to the inner part of the limiting connection cover and is located behind the fixing frame.

[0009] Preferably, the driven gear is connected between the tooth groove and the driving gear through a gear groove, and the gear groove is opened in the inner wall of the lower end of the limiting frame. The limiting frame is communicated with the inner part of the crushing cylinder through the gear groove.

[0010] Preferably, the driven gear is rotatably connected to the inner part of the gear groove through a gear seat, and the rear end of the gear seat is fixedly connected to the lower side of the center of the rear end inner wall of the limiting connection cover. The upper and lower ends of the driven gear are respectively engaged with the tooth groove and the driving gear.

[0011] Preferably, a plurality of secondary crushing roller plates are fixedly connected to the outer part of the cylindrical outer wall of the crushing filter cylinder, and a plurality of secondary crushing roller plates are all rotatably connected between the crushing cylinder and the crushing filter cylinder.

[0012] Preferably, a plurality of the primary filter holes are all opened between a plurality of secondary crushing roller plates. A plurality of secondary filter holes are opened in the inner part of the lower end of the crushing cylinder and are communicated with the inner part of the collection box through the plurality of secondary filter holes.

[0013] Compared with the prior art, the utility model provides a crusher for the production of ursodeoxycholic acid preparations, which has the following beneficial effects:

[0014] 1. Double-stage crushing system: A double-stage crushing system including primary crushing and secondary crushing is designed. Through different crushing roller plates and filter hole configurations, the staged crushing of ursodeoxycholic acid raw materials is achieved, improving the crushing efficiency and the fineness of the powder.

[0015] 2. Extrusion ball-assisted crushing: Extrusion balls are introduced into the gaps between the primary and secondary crushing roller plates. By utilizing the rolling action of the balls, the crushing force of the raw materials is enhanced, improving the crushing quality and efficiency.

[0016] 3. Reverse rotation mechanism: By setting a gear transmission system between the crushing rotating shaft and the crushing filter cylinder, the reverse rotation of the crushing filter cylinder and the crushing roller plate is achieved, which helps the uniform distribution of raw materials during the crushing process and efficient crushing.

[0017] 4. Classification filtration design: Primary filter holes and secondary filter holes with different pore sizes are adopted to achieve the classification filtration of the crushed raw materials, ensuring that the particle size of the final product meets the requirements of preparation production.

[0018] 5. Integrated crushing and collection: The entire crushing process is completed within a closed system. Through the integrated design of the crushing cylinder and the collection box, the crushed raw materials can directly enter the collection box, facilitating subsequent collection and export.

[0019] 6. Automatic control: Through the drive of the crushing motor, the automatic control of the crushing process is achieved, reducing manual intervention and improving production efficiency and operation safety. Description of the Drawings

[0020] Figure 1 It is a three-dimensional structural schematic diagram of the crusher of the utility model.

[0021] Figure 2 It is a three-dimensional sectional structural schematic diagram of the crusher of the utility model.

[0022] Figure 3 It is a schematic diagram of the connection structure of the crushing cylinder of the utility model.

[0023] Figure 4 It is of the utility model Figure 3 The enlarged schematic diagram at A in

[0024] Figure 5 It is a schematic diagram of the connection structure of the crushing filter cylinder of the utility model.

[0025] Figure 6 It is a schematic diagram of the connection structure of the crushing rotating shaft of the utility model.

[0026] In the figure: 1. Crushing cylinder; 2. Connecting pipe; 3. Hopper; 4. Collection box; 5. Support leg; 6. Limiting frame; 7. Limiting connection cover; 8. Fixed frame; 9. Crushing rotating shaft; 10. Primary crushing roller plate; 11. Crushing motor; 12. Limiting rotating ring; 13. Crushing filter cylinder; 14. Primary filter holes; 15. Tooth grooves; 16. Driven gear; 17. Driving gear; 18. Gear grooves; 19. Gear seat; 20. Secondary crushing roller plate; 21. Secondary filter holes. Detailed implementation manners

[0027] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0028] The present invention provides as Figures 1-6A crusher for the production of ursodeoxycholic acid preparations is shown, including a crushing cylinder 1. A connecting pipe 2 is connected to the center of the rear end of the crushing cylinder 1. A hopper 3 is connected to the upper end of the connecting pipe 2. A collection box 4 is fixedly connected to the lower end of the crushing cylinder 1. Support legs 5 are fixedly connected to the four corners of the lower end of the collection box 4 for supporting the crushing cylinder 1 and the collection box 4. A limiting frame 6 is fixedly connected to the inner part of the front end of the connecting pipe 2. A limiting connection cover 7 with an opening forward is fixedly connected to the inner part of the front end of the crushing cylinder 1. The limiting frame 6 and the limiting connection cover 7 are used for restricting the position of the crushing rotating shaft 9. A fixing frame 8 is fixedly connected to the inner part of the front end of the limiting connection cover 7 for fixing the crushing motor 11. The front end of the limiting frame 6 is rotatably connected to a crushing rotating shaft 9, and the front end of the crushing rotating shaft 9 passes through the inner parts of the centers of the limiting connection cover 7 and the fixing frame 8 from front to back. A plurality of primary crushing roller plates 10 are fixedly connected to the outer rear side of the crushing rotating shaft 9. A crushing motor 11 is arranged at the front end of the crushing rotating shaft 9, and the front end of the crushing rotating shaft 9 is rotatably connected to the inner part of the center of the rear end of the crushing motor 11. The crushing motor 11 is fixedly connected to the front end of the fixing frame 8. A crushing filter cylinder 13 is rotatably connected between the inner walls of the front and rear ends of the crushing cylinder 1 through two limiting rotating rings 12, and the two limiting rotating rings 12 are respectively fixedly connected to the outer parts of the centers of the inner walls of the front and rear ends of the crushing cylinder 1. The crushing filter cylinder 13 is sleeved outside a plurality of primary crushing roller plates 10, and the front end of the crushing filter cylinder 13 is sleeved outside the limiting connection cover 7. A plurality of primary filter holes 14 are opened in the inner part of the cylindrical outer wall of the crushing filter cylinder 13. A plurality of secondary crushing roller plates 20 are fixedly connected to the outer part of the cylindrical outer wall of the crushing filter cylinder 13. A plurality of secondary filter holes 21 are opened in the inner part of the lower end of the crushing cylinder 1. The ursodeoxycholic acid raw material is put into the hopper 3 and introduced into the crushing filter cylinder 13 arranged at the center of the inner part of the crushing cylinder 1 through the connecting pipe 2. The crushing cylinder 1 performs primary crushing through a plurality of primary crushing roller plates 10 arranged inside. The raw material after primary crushing is introduced between the crushing cylinder 1 and the crushing filter cylinder 13 through a plurality of primary filter holes 14 and undergoes secondary crushing through a plurality of secondary crushing roller plates 20. Finally, it is introduced into the collection box 4 through a plurality of secondary filter holes 21 opened in the inner part of the lower end of the crushing cylinder 1 for collection and export, so as to obtain the ursodeoxycholic acid raw material powder, and the ursodeoxycholic acid preparation is made with the ursodeoxycholic acid raw material powder.

[0029] Among them, a plurality of extrusion balls are placed inside the gaps between the multiple first-stage crushing roller plates 10 and inside the gaps between the multiple second-stage crushing roller plates 20. The multiple first-stage crushing roller plates 10 are fixedly connected to the outside of the crushing rotating shaft 9. The crushing rotating shaft 9 is driven to rotate by a crushing motor 11 provided at the front end. When the crusher performs first-stage crushing on the ursodeoxycholic acid raw material, the multiple first-stage crushing roller plates 10 rotate inside the crushing filter cylinder 13, causing the multiple extrusion balls to roll back and forth inside the gaps between the multiple first-stage crushing roller plates 10. At the same time, the multiple first-stage crushing roller plates 10 can scrape the raw material into the gaps through the edges. After the raw material enters the gaps, it will be rolled back and forth by the extrusion balls, so that the ursodeoxycholic acid raw material is crushed. And when the diameter of the crushed ursodeoxycholic acid raw material is smaller than the pore diameter of the first-stage filter holes 14, the crushed ursodeoxycholic acid raw material will enter the space between the crushing cylinder 1 and the crushing filter cylinder 13 through the first-stage filter holes 14 for second-stage crushing.

[0030] Preferably, a tooth groove 15 is provided inside the front side of the cylindrical inner wall of the crushing filter cylinder 13. A driven gear 16 is rotatably connected to the inside of the lower end of the tooth groove 15. An upper end of the driven gear 16 is rotatably connected to a driving gear 17. The driving gear 17 is fixedly connected to the outside of the crushing rotating shaft 9. The driving gear 17 is rotatably connected inside the limit connection cover 7 and is located behind the fixed frame 8. The driven gear 16 is connected between the tooth groove 15 and the driving gear 17 through a gear groove 18. The gear groove 18 is provided inside the inner wall of the lower end of the limit frame 6. During the process of first-stage crushing, the crushing motor 11 drives the multiple first-stage crushing roller plates 10 to rotate through the crushing rotating shaft 9, and drives the crushing filter cylinder 13 to rotate in the opposite direction to the first-stage crushing roller plates 10 through the tooth groove 15, the driven gear 16 and the driving gear 17, so that the ursodeoxycholic acid raw material inside the crushing filter cylinder 13 can more easily enter the gaps between the multiple first-stage crushing roller plates 10. At the same time, it can turn the ursodeoxycholic acid raw material, making it easier for the crushed ursodeoxycholic acid raw material with a diameter smaller than the pore diameter of the first-stage filter holes 14 to pass through the inside of the first-stage filter holes 14, thereby improving the crushing efficiency of the ursodeoxycholic acid raw material and at the same time improving the crushing uniformity.

[0031] Preferably, since the driven gear 16 is rotatably connected to the inside of the gear groove 18 through a gear seat 19, and the rear end of the gear seat 19 is fixedly connected to the lower side of the center of the rear inner wall of the limit connection cover 7, the upper and lower ends of the driven gear 16 are respectively engaged with the tooth groove 15 and the driving gear 17. Therefore, the driving gear 17 can drive the crushing filter cylinder 13 to rotate in the opposite direction to the first-stage crushing roller plates 10 through the driven gear 16.

[0032] Preferably, after the Ursodeoxycholic Acid raw material enters the inside of the crushing cylinder 1 and the crushing filter cylinder 13, multiple secondary crushing roller plates 20 rotate between the crushing cylinder 1 and the crushing filter cylinder 13 driven by the crushing filter cylinder 13, and scrape the Ursodeoxycholic Acid raw material into the gap between the multiple secondary crushing roller plates 20 through the edge for secondary crushing. The Ursodeoxycholic Acid raw material entering the gap is crushed again under the rolling pressure of multiple extrusion balls. When the diameter of the Ursodeoxycholic Acid raw material is smaller than the aperture of the secondary filter hole 21, the Ursodeoxycholic Acid raw material will enter the inside of the collection box 4 through the secondary filter hole 21. The collection box 4 collects the Ursodeoxycholic Acid raw material with the crushing fineness reaching the standard, and finally exports it through the export pipe at the lower end. Since the aperture of the secondary filter hole 21 is smaller than the aperture of the primary filter hole 14, the Ursodeoxycholic Acid raw material entering the inside of the collection box 4 is finer than the Ursodeoxycholic Acid raw material entering between the crushing cylinder 1 and the crushing filter cylinder 13. Through primary and secondary crushing, the Ursodeoxycholic Acid raw material meets the preparation standard.

[0033] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A pulverizer for the production of ursodeoxycholic acid preparations, characterized in that: The invention comprises a crushing cylinder (1), wherein the center of the rear end of the crushing cylinder (1) is connected to a connecting pipe (2), the upper end of the connecting pipe (2) is connected to a hopper (3), the lower end of the crushing cylinder (1) is fixedly connected to a collecting box (4), the four corners of the lower end of the collecting box (4) are fixedly connected to supporting legs (5), the front end of the connecting pipe (2) is fixedly connected to a limiting frame (6), the front end of the crushing cylinder (1) is fixedly connected to a limiting connecting cover (7) opening forward, the front end of the limiting connecting cover (7) is fixedly connected to a fixing frame (8), the front end of the limiting frame (6) is rotatably connected to a crushing shaft (9), and the front end of the crushing shaft (9) penetrates the center of the limiting connecting cover (7) and the fixing frame (8) from front to back, and the rear side of the crushing shaft (9) is fixedly connected to the outside. A plurality of primary pulverizing rollers (10) are fixedly connected thereto; a pulverizing motor (11) is arranged at the front end of the pulverizing shaft (9), and the front end of the pulverizing shaft (9) is rotatably connected to the inside of the center of the rear end of the pulverizing motor (11); the pulverizing motor (11) is fixedly connected to the front end of the fixed frame (8); a pulverizing filter cartridge (13) is rotatably connected between the inner walls at the front and rear ends of the pulverizing cylinder (1) through two limiting rotating rings (12), and the two limiting rotating rings (12) are respectively fixedly connected to the outside of the center of the inner walls at the front and rear ends of the pulverizing cylinder (1); the pulverizing filter cartridge (13) is sleeved on the outside of the plurality of primary pulverizing rollers (10), and the front end of the pulverizing filter cartridge (13) is sleeved on the outside of the limiting connection cover (7); and a plurality of primary filter holes (14) are provided inside the cylindrical outer wall of the pulverizing filter cartridge (13).

2. A pulverizer for the production of ursodeoxycholic acid preparations according to claim 1, characterized in that: A tooth groove (15) is provided inside the front side of the cylindrical inner wall of the crushing filter cartridge (13), and a driven gear (16) is rollingly connected inside the lower end of the tooth groove (15).

3. A pulverizer for the production of ursodeoxycholic acid preparations according to claim 2, characterized in that: The upper end of the driven gear (16) is rollingly connected to a driving gear (17), and the driving gear (17) is fixedly connected to the outside of the pulverizing shaft (9). The driving gear (17) is rotatably connected to the inside of the limiting connection cover (7) and is located at the rear side of the fixing frame (8).

4. A pulverizer for the production of ursodeoxycholic acid preparations according to claim 3, characterized in that: The driven gear (16) is connected between the tooth groove (15) and the driving gear (17) via a gear groove (18), and the gear groove (18) is provided inside the inner wall of the lower end of the limiting frame (6), and the limiting frame (6) is connected to the inside of the pulverizing cylinder (1) via the gear groove (18).

5. A pulverizer for the production of ursodeoxycholic acid preparations according to claim 4, characterized in that: The driven gear (16) is rotatably connected to the inside of the gear groove (18) via a gear seat (19), and the rear end of the gear seat (19) is fixedly connected to the lower side of the center of the rear end inner wall of the limiting connection cover (7), and the upper and lower ends of the driven gear (16) are respectively meshed with the tooth groove (15) and the driving gear (17).

6. A pulverizer for the production of ursodeoxycholic acid preparations according to claim 1, characterized in that: A plurality of secondary pulverizing rollers (20) are fixedly connected to the outside of the cylindrical outer wall of the pulverizing filter cartridge (13), and the plurality of secondary pulverizing rollers (20) are rotatably connected between the pulverizing cartridge (1) and the pulverizing filter cartridge (13).

7. A pulverizer for the production of ursodeoxycholic acid preparations according to claim 6, characterized in that: The plurality of primary filter holes (14) are arranged between the plurality of secondary crushing rollers (20), and the lower end of the crushing cylinder (1) is provided with a plurality of secondary filter holes (21), which are connected to the interior of the collection box (4) through the plurality of secondary filter holes (21).

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