Preparation device for primidone

Abstract

The utility model relates to the technical field of preparation of primidone, in particular to a preparation device for primidone, which comprises a main body mechanism, a control mechanism, a functional mechanism and a reaction mechanism, the control mechanism is positioned on one side of the main body mechanism, the functional mechanism is positioned inside the main body mechanism, and the reaction mechanism is positioned inside the main body mechanism. The control panel fixedly mounted on one side of the preparation device body is used for controlling the condenser, the dropwise adding regulating valve, the air suction device, the magnetic stirrer and the heating module in the equipment, and the indicator lamp on one side of the equipment is used for displaying the running state of electronic elements in the equipment. The thermometer and the indicator lamp on one side of the equipment are used for displaying the temperature and the pressure in the reaction tank, hydrogen sulfide generated during preparation of the primidone can be sucked into the oxidant reaction box by the gas suction device, and the hydrogen sulfide reacts with the oxidant to form a harmless product; a dropwise adding regulating valve is fixedly mounted in the second connecting pipeline and is used for adding hydrochloric acid into the reaction tank to carry out reduction preparation of the primidone.

Description

Technical Field

[0001] The utility model relates to the technical field of primidone preparation, in particular to a preparation device for primidone. Background Technique

[0002] Primidone, also known as mysoline, primidone, primidone, with the chemical name of 5-ethyl-5-phenyl-dihydro-4,6(1H,5H)-pyrimidinedione, is an organic compound with the chemical formula of C12H14N2O2, a molecular weight of 325.4242, a melting point of 281-282 °C, a slightly bitter taste, no acidity, slightly soluble in alcohol, almost insoluble in water, acetone or benzene, mainly used as an anti-epileptic drug, clinically mainly used for the monotherapy or combination therapy of grand mal seizures, simple partial seizures and complex partial seizures of epilepsy, and also used for the treatment of essential tremor and senile tremor. The currently disclosed reduction of thiophenylbarbituric acid is as follows: diethyl ethylphenylmalonate and thiourea are refluxed for 9 hours and cooled to 0 °C; ethanol is added, and hydrochloric acid is dropped into it at 0-5 °C until the pH = 3-3.5; zinc powder is added, the temperature is raised to reflux, and hydrochloric acid is slowly added to keep the acid content in the reaction solution at 2-3%. After the addition is completed, it is kept warm for 3 hours; filtered while hot, the filtrate is recycled ethanol; cooled to 20 °C, water is added, filtered, and the filter cake is washed to obtain the primidone product.

[0003] As disclosed in the authorized publication number CN204675849U, a wastewater pretreatment device for primidone synthesis is disclosed, including a wastewater collection tank and a full-automatic rectification tower. The full-automatic rectification tower is provided with a liquid inlet, an air outlet and a reflux liquid inlet. The wastewater collection tank is connected to the liquid inlet of the full-automatic rectification tower through a wastewater pipeline. A feeding pump and a high-level tank are successively arranged on the wastewater pipeline. The air outlet of the full-automatic rectification tower is successively connected with a first condenser and a second condenser. The liquid outlet of the second condenser is connected with a condensate pipeline. An ethanol liquid pipeline and a reflux liquid pipeline are arranged in parallel on the condensate pipeline. The end of the ethanol liquid pipeline is connected with an ethanol collection tank. A sampling valve is arranged at the initial section of the reflux liquid pipeline, and the end is connected with the reflux liquid inlet of the full-automatic rectification tower. After adopting the above structure, the beneficial effect is that the ethanol separation effect in the primidone wastewater is good, the recovery is sufficient and can be reused, and the production cost can be reduced. However, during its use, the waste gas cannot be treated and the safety is relatively poor. Therefore, we propose a preparation device for primidone to solve the problems that the waste gas of traditional equipment cannot be treated and the safety is relatively poor. Content of the Utility Model

[0004] The purpose of the utility model is to provide a preparation device for primidone to solve the problems put forward in the above background technique.

[0005] To achieve the above purpose, the utility model provides the following technical solutions:

[0006] A preparation device for primidone, comprising a main body mechanism, a control mechanism, a functional mechanism, and a reaction mechanism. The control mechanism is located on one side of the main body mechanism, the functional mechanism is located inside the main body mechanism, and the reaction mechanism is located inside the main body mechanism. The main body mechanism includes a preparation device main body, equipment support legs, connecting hinges, a sealing door, a handle, a sealing strip, and a transparent observation port. The preparation device main body is fixedly installed at the top of the equipment support legs, the equipment support legs are fixedly installed at the bottom of the preparation device main body, the connecting hinges are fixedly installed on one side of the preparation device main body, the sealing door is fixedly installed on one side of the connecting hinges, the handle is fixedly installed on one side of the sealing door, the sealing strip is fixedly installed on one side of the sealing door, and the transparent observation port is fixedly installed on one side of the preparation device main body.

[0007] Preferably, the control mechanism includes a pressure gauge, a thermometer, an indicator light, a control panel, a storage battery, a condenser, a dropping regulating valve, an air suction device, a magnetic stirrer, and a heating module. The pressure gauge is fixedly installed on one side of the preparation device main body, and the thermometer is fixedly installed on one side of the preparation device main body.

[0008] Preferably, the functional mechanism includes a top cover plate, an oxidant reaction tank, a hydrochloric acid storage tank, an oxidant addition pipeline, a first sealing ring, a hydrochloric acid addition pipeline, a second sealing ring, a waste liquid discharge pipeline, a sealing plug, a first connecting pipeline, a second connecting pipeline, and a feed pipeline. The top cover plate is fixedly installed at the top of the preparation device main body, and the oxidant reaction tank is fixedly installed inside the preparation device main body.

[0009] Preferably, the reaction mechanism includes a reaction tank, a magnetic stirring rod, a stirring head, and a fixing frame. The reaction tank is fixedly installed inside the preparation device main body, and the magnetic stirring rod is fixedly installed inside the reaction tank.

[0010] Preferably, the indicator light is fixedly installed on one side of the preparation device main body, the control panel is fixedly installed on one side of the preparation device main body, the storage battery is fixedly installed inside the preparation device main body, the condenser is fixedly installed inside the preparation device main body, the dropping regulating valve is fixedly installed inside the second connecting pipeline, the air suction device is fixedly installed on one side of the first connecting pipeline and the oxidant reaction tank, the magnetic stirrer is fixedly installed at the top of the reaction tank, and the heating module is fixedly installed at the bottom of the reaction tank.

[0011] Preferably, the hydrochloric acid storage tank is fixedly installed inside the main body of the preparation device, the oxidant addition pipeline is fixedly installed at the top of the oxidant reaction tank, the first sealing ring is fixedly installed on one side of the oxidant addition pipeline, the hydrochloric acid addition pipeline is fixedly installed at the top of the hydrochloric acid storage tank, the second sealing ring is fixedly installed on one side of the hydrochloric acid addition pipeline, the waste liquid discharge pipeline is fixedly installed on one side of the oxidant reaction tank, the sealing plug is fixedly installed on one side of the waste liquid discharge pipeline, the first connecting pipeline is fixedly installed on one side of the reaction tank and the suction device, the second connecting pipeline is fixedly installed on one side of the reaction tank and the hydrochloric acid storage tank, and the feeding pipeline is fixedly installed on one side of the reaction tank.

[0012] Preferably, the stirring head is fixedly installed on one side of the magnetic stirring rod, and the fixing frame is fixedly installed inside the reaction tank.

[0013] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0014] 1. For this preparation device for primidone, the condenser, dropping regulating valve, suction device, magnetic stirrer, and heating module inside the device are controlled by the control panel fixedly installed on one side of the main body of the preparation device. The indicator lights on one side of the device are used to display the operating status of the electronic components inside the device. The thermometer and indicator lights on one side of the device are used to display the temperature and pressure inside the reaction tank. The hydrogen sulfide generated during the preparation of primidone will be sucked into the oxidant reaction tank by the suction device, and the hydrogen sulfide reacts with the oxidant to form harmless products.

[0015] 2. For this preparation device for primidone, the hydrochloric acid inside the hydrochloric acid storage tank is connected to the reaction tank through the second connecting pipeline on one side. A dropping regulating valve is fixedly installed inside the second connecting pipeline to add hydrochloric acid to the reaction tank for the reduction preparation of primidone. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 is the overall structural schematic diagram of the present utility model;

[0017] Figure 2 is the cross-sectional structural schematic diagram of the present utility model;

[0018] Figure 3 is the schematic diagram of the sealing door of the present utility model;

[0019] Figure 4 is the schematic diagram of the magnetic stirring rod of the present utility model;

[0020] Figure 5 is the schematic diagram of the fixing frame of the present utility model.

[0021] In the figure: 100, main body of the preparation device; 101, equipment support leg; 102, connecting hinge; 103, sealing door; 104, handle; 105, sealing strip; 106, transparent observation port; 200, pressure gauge; 201, thermometer; 202, indicator light; 203, control panel; 204, storage battery; 205, condenser; 206, dropping regulating valve; 207, suction device; 208, magnetic stirrer; 209, heating module; 300, top cover plate; 301, oxidant reaction tank; 302, hydrochloric acid storage tank; 303, oxidant addition pipeline; 304, first sealing ring; 305, hydrochloric acid addition pipeline; 306, second sealing ring; 307, waste liquid discharge pipeline; 308, sealing plug; 309, first connecting pipeline; 310, second connecting pipeline; 311, feeding pipeline; 400, reaction tank; 401, magnetic stirring bar; 402, stirring head; 403, fixing rack. Specific implementation mode

[0022] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0023] Please refer to Figures 1 - 5 As shown, a technical solution provided by the present invention:

[0024] A preparation device for primidone, comprising a main body mechanism, a control mechanism, a functional mechanism, and a reaction mechanism. The control mechanism is located on one side of the main body mechanism, the functional mechanism is located inside the main body mechanism, and the reaction mechanism is located inside the main body mechanism. The main body mechanism includes the main body 100 of the preparation device, the equipment support leg 101, the connecting hinge 102, the sealing door 103, the handle 104, the sealing strip 105, and the transparent observation port 106. The main body 100 of the preparation device is fixedly installed at the top of the equipment support leg 101, the equipment support leg 101 is fixedly installed at the bottom of the main body 100 of the preparation device, the connecting hinge 102 is fixedly installed on one side of the main body 100 of the preparation device, the sealing door 103 is fixedly installed on one side of the connecting hinge 102, the handle 104 is fixedly installed on one side of the sealing door 103, the sealing strip 105 is fixedly installed on one side of the sealing door 103, and the transparent observation port 106 is fixedly installed on one side of the main body 100 of the preparation device.

[0025] In this example, preferably, the control mechanism includes a barometer 200, a thermometer 201, an indicator light 202, a control panel 203, a storage battery 204, a condenser 205, a dropping regulating valve 206, a suction device 207, a magnetic stirrer 208, and a heating module 209. The barometer 200 is fixedly installed on one side of the main body 100 of the preparation device, and the thermometer 201 is fixedly installed on one side of the main body 100 of the preparation device.

[0026] In this example, preferably, the functional mechanism includes a top cover plate 300, an oxidant reaction tank 301, a hydrochloric acid storage tank 302, an oxidant addition pipeline 303, a first sealing ring 304, a hydrochloric acid addition pipeline 305, a second sealing ring 306, a waste liquid discharge pipeline 307, a sealing plug 308, a first connecting pipeline 309, a second connecting pipeline 310, and a feed pipeline 311. The top cover plate 300 is fixedly installed at the top of the main body 100 of the preparation device, and the oxidant reaction tank 301 is fixedly installed inside the main body 100 of the preparation device.

[0027] In this example, preferably, the reaction mechanism includes a reaction tank 400, a magnetic stirring rod 401, a stirring head 402, and a fixing frame 403. The reaction tank 400 is fixedly installed inside the main body 100 of the preparation device, and the magnetic stirring rod 401 is fixedly installed inside the reaction tank 400.

[0028] In this example, preferably, the indicator light 202 is fixedly installed on one side of the main body 100 of the preparation device, the control panel 203 is fixedly installed on one side of the main body 100 of the preparation device, the storage battery 204 is fixedly installed inside the main body 100 of the preparation device, the condenser 205 is fixedly installed inside the main body 100 of the preparation device, the dropping regulating valve 206 is fixedly installed inside the second connecting pipeline 310, the suction device 207 is fixedly installed on one side of the first connecting pipeline 309 and the oxidant reaction tank 301, the magnetic stirrer 208 is fixedly installed at the top of the reaction tank 400, and the heating module 209 is fixedly installed at the bottom of the reaction tank 400.

[0029] In this embodiment, preferably, the hydrochloric acid storage tank 302 is fixedly installed inside the preparation device main body 100, the oxidant addition pipeline 303 is fixedly installed at the top of the oxidant reaction tank 301, the first sealing ring 304 is fixedly installed on one side of the oxidant addition pipeline 303, the hydrochloric acid addition pipeline 305 is fixedly installed at the top of the hydrochloric acid storage tank 302, the second sealing ring 306 is fixedly installed on one side of the hydrochloric acid addition pipeline 305, the waste liquid discharge pipeline 307 is fixedly installed on one side of the oxidant reaction tank 301, the sealing plug 308 is fixedly installed on one side of the waste liquid discharge pipeline 307, the first connection pipeline 309 is fixedly installed on one side of the reaction tank 400 and the suction device 207, the second connection pipeline 310 is fixedly installed on one side of the reaction tank 400 and the hydrochloric acid storage tank 302, and the feed pipeline 311 is fixedly installed on one side of the reaction tank 400.

[0030] In this embodiment, preferably, the stirring head 402 is fixedly installed on one side of the magnetic stirring rod 401, and the fixing frame 403 is fixedly installed inside the reaction tank 400.

[0031] When the preparation device for primidone of this embodiment is in use, the condenser 205, the dropping regulating valve 206, the suction device 207, the magnetic stirrer 208, and the heating module 209 inside the device are controlled through the control panel 203 fixedly installed on one side of the preparation device main body 100. The indicator light 202 on one side of the device is used to display the operating state of the electronic components inside the device, and the thermometer 201 and the indicator light 202 on one side of the device are used to display the temperature and pressure inside the reaction tank 400.

[0032] The hydrogen sulfide generated during the preparation of primidone will be sucked into the oxidant reaction tank 301 by the suction device 207. The hydrogen sulfide reacts with the oxidant to form harmless products. The hydrochloric acid inside the hydrochloric acid storage tank 302 is connected to the reaction tank 400 through the second connection pipeline 310 on one side. A dropping regulating valve 206 is fixedly installed inside the second connection pipeline 310 for adding hydrochloric acid to the reaction tank 400 to prepare primidone by reduction.

[0033] The above shows and describes the basic principles, main features, and advantages of the present invention. Those skilled in the art of this industry should understand that the present invention is not limited by the above embodiments. The above embodiments and the descriptions in the specification are only preferred examples of the present invention and are not used to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.

Claims

1. A device for preparing primidone, comprising a main mechanism, a control mechanism, a functional mechanism, and a reaction mechanism, characterized in that: The control mechanism is located on one side of the main mechanism, the functional mechanism is located inside the main mechanism, and the reaction mechanism is located inside the main mechanism. The main mechanism comprises a preparation device body (100), a device support leg (101), a connecting hinge (102), a sealing door (103), a handle (104), a sealing strip (105), and a transparent observation port (106). The preparation device body (100) is fixedly mounted on the top of the device support leg (101), the device support leg (101) is fixedly mounted on the bottom of the preparation device body (100), the connecting hinge (102) is fixedly mounted on one side of the preparation device body (100), the sealing door (103) is fixedly mounted on one side of the connecting hinge (102), the handle (104) is fixedly mounted on one side of the sealing door (103), the sealing strip (105) is fixedly mounted on one side of the sealing door (103), and the transparent observation port (106) is fixedly mounted on one side of the preparation device body (100).

2. A device for preparing primidone according to claim 1, characterized in that: The control mechanism comprises a barometer (200), a thermometer (201), an indicator light (202), a control panel (203), a storage battery (204), a condenser (205), a dripping regulating valve (206), an air suction device (207), a magnetic stirrer (208), and a heating module (209); the barometer (200) is fixedly mounted on one side of a preparation device body (100); and the thermometer (201) is fixedly mounted on one side of a preparation device body (100).

3. The device for preparing primidone according to claim 1, characterized in that: The functional mechanism comprises a top cover plate (300), an oxidant reaction box (301), a hydrochloric acid storage box (302), an oxidant addition pipeline (303), a first sealing ring (304), a hydrochloric acid addition pipeline (305), a second sealing ring (306), a waste liquid discharge pipeline (307), a sealing plug (308), a first connecting pipeline (309), a second connecting pipeline (310), and a feed pipeline (311); the top cover plate (300) is fixedly mounted on the top of the preparation device body (100), and the oxidant reaction box (301) is fixedly mounted inside the preparation device body (100).

4. The device for preparing primidone according to claim 1, characterized in that: The reaction mechanism comprises a reaction tank (400), a magnetic stirring rod (401), a stirring head (402), and a fixing frame (403); the reaction tank (400) is fixedly installed inside the preparation device body (100); and the magnetic stirring rod (401) is fixedly installed inside the reaction tank (400).

5. A device for preparing primidone according to claim 2, characterized in that: The indicator light (202) is fixedly mounted on one side of the preparation device body (100), the control panel (203) is fixedly mounted on one side of the preparation device body (100), the storage battery (204) is fixedly mounted inside the preparation device body (100), the condenser (205) is fixedly mounted inside the preparation device body (100), the dripping regulating valve (206) is fixedly mounted inside the second connecting pipe (310), the air suction device (207) is fixedly mounted on one side of the first connecting pipe (309) and the oxidant reaction box (301), the magnetic stirrer (208) is fixedly mounted on the top of the reaction tank (400), and the heating module (209) is fixedly mounted on the bottom of the reaction tank (400).

6. The device for preparing primidone according to claim 3, characterized in that: The hydrochloric acid storage tank (302) is fixedly installed inside the preparation device body (100), the oxidant addition pipeline (303) is fixedly installed on the top of the oxidant reaction tank (301), the first sealing ring (304) is fixedly installed on one side of the oxidant addition pipeline (303), the hydrochloric acid addition pipeline (305) is fixedly installed on the top of the hydrochloric acid storage tank (302), the second sealing ring (306) is fixedly installed on one side of the hydrochloric acid addition pipeline (305), the waste liquid discharge pipeline (307) is fixedly installed on one side of the oxidant reaction tank (301), the sealing plug (308) is fixedly installed on one side of the waste liquid discharge pipeline (307), the first connecting pipeline (309) is fixedly installed on one side of the reaction tank (400) and the air suction device (207), the second connecting pipeline (310) is fixedly installed on one side of the reaction tank (400) and the hydrochloric acid storage tank (302), and the feeding pipeline (311) is fixedly installed on one side of the reaction tank (400).

7. The device for preparing primidone according to claim 4, characterized in that: The stirring head (402) is fixedly mounted on one side of the magnetic stirring rod (401), and the fixing frame (403) is fixedly mounted inside the reaction tank (400).

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