Multi-position reagent sample adding manipulator for pathological tissue independent drop dyeing system
By designing a multi-position reagent sample loading robot, the use of the X-axis, Y-axis and Z-axis modules to realize intelligent automation of reagent sample loading, solving the problem of large space occupied by traditional robots and adapting to the dyeing needs of tissue slices of different sizes and shapes.
Patent Information
- Application Number
- CN202422164401.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-04
- Publication Date
- 2025-07-08
- Estimated Expiration
- 2034-09-04
AI Technical Summary
Traditional robots take up a large space in HE dyeing machines and the instrument size is huge, resulting in insufficient space use.
A multi-position reagent sample reagent manipulator is designed, including an X-axis module, a Y-axis module and a Z-axis module. Through the actions of these modules, the X-axis lateral movement, the Y-axis longitudinal movement and the Z-axis vertical lifting and lowering of the reagent sample reagent is realized. Combined with the reagent liquid system, intelligent automatic sample reagent is realized.
It realizes intelligent automation of reagent sample addition, compact structure and small size, solving the problem of large space occupied by traditional robots and adapts to the dyeing needs of tissue sections of different sizes and shapes.
Smart Images

Figure CN223071380U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical devices, in particular to a multi-position reagent adding manipulator for a single-drop staining system of pathological tissues. Background Art
[0002] Single-drop HE staining is a commonly used staining method for staining tissue sections in histological research to observe and analyze the structure of tissues and the morphology of tissue cells. Single-drop HE staining means placing tissue section specimens in a staining trough frame and going through a series of processes such as heating the slide, dewaxing, staining, cleaning, and covering the slide to ensure the uniformity and accuracy of staining. The single-drop HE staining machine is convenient to operate, has a high-definition staining effect, and shortens the staining time. It is widely used in medical biology and pathological diagnosis. It can adapt to tissue sections of different sizes and shapes for staining treatment, reduce manual operation, and provide more accurate histological information.
[0003] Currently, the mainstream foreign HE staining machines all adopt a manipulator structure for reagent addition. However, since they basically use a slide tray for loading and unloading, the manipulator mechanism is relatively large. There are reagent adding heads corresponding to the number of slides in the slide tray at a reagent dropping position, occupying a large space, and the instrument size is huge, with obvious deficiencies in space utilization. Summary of the Utility Model
[0004] The purpose of the utility model is to provide a multi-position reagent adding manipulator for a single-drop staining system of pathological tissues, aiming to solve the problem that the traditional manipulator occupies a large space and the instrument size is huge.
[0005] To achieve the above object, the utility model provides a multi-position reagent adding manipulator for a separate dripping staining system of pathological tissues, which includes an X-axis module, a first Y-axis module, a second Y-axis module, a first Z-axis module, a second Z-axis module and a reagent adding head group; the X-axis module includes an X-axis driving member, an X-axis bottom plate, an X-axis linear slide rail, an X-axis slider, an X-axis sensor stop piece and an X-axis origin sensor, the X-axis linear slide rail is fixedly arranged on the X-axis bottom plate, the X-axis slider is arranged on one side of the X-axis linear slide rail, the X-axis driving member is arranged on one side of the X-axis slider and the X-axis bottom plate, the X-axis origin sensor is arranged on one side of the X-axis driving member, and the sensor stop piece is fixedly arranged on one side of the X-axis slider; the first Z-axis module includes a first Z-axis driving member, a first Z-axis linear slide rail, a first Z-axis slider, a first Z-axis origin sensor, a first Z-axis sensor stop piece and a Z-axis bottom plate, the second Z-axis module includes a second Z-axis driving member, a second Z-axis linear slide rail, a second Z-axis slider, a second Z-axis origin sensor and a second Z-axis sensor stop piece, the Z-axis bottom plate is fixedly arranged on the X-axis slider, the first Z-axis linear slide rail, the second Z-axis linear slide rail, the first Z-axis origin sensor and the second Z-axis origin sensor are respectively fixedly arranged on the Z-axis bottom plate, the first Z-axis slider is arranged on one side of the first Z-axis linear slide rail, the second Z-axis slider is arranged on one side of the second Z-axis linear slide rail, the first Z-axis sensor stop piece is fixedly arranged on one side of the first Z-axis slider, the second Z-axis sensor stop piece is fixedly arranged on one side of the second Z-axis slider, the first Z-axis driving member is arranged on one side of the first Z-axis slider and the Z-axis bottom plate, the second Z-axis driving member is arranged on one side of the second Z-axis slider and the Z-axis bottom plate, the first Z-axis origin sensor is arranged on one side of the first Z-axis driving member, and the second Z-axis origin sensor is arranged on one side of the second Z-axis driving member; the first Y-axis module includes a first Y-axis driving member, a first Y-axis linear slide rail, a first Y-axis slider, a first Y-axis sensor stop piece and a first Y-axis origin sensor, the first Y-axis linear slide rail is fixedly arranged on one side of the first Z-axis slider, the first Y-axis slider is arranged on one side of the first Y-axis linear slide rail, the first Y-axis driving member is arranged on one side of the first Y-axis slider, the first Y-axis origin sensor is arranged on one side of the first Y-axis driving member, and the first Y-axis sensor stop piece is fixedly arranged on one side of the first Z-axis slider;The second Y-axis module includes a second Y-axis driving member, a second Y-axis linear slide rail, a second Y-axis slider, a second Y-axis sensor baffle, and a second Y-axis origin sensor. The second Y-axis linear slide rail is fixedly arranged on one side of the second Z-axis slider. The second Y-axis slider is arranged on one side of the second Y-axis linear slide rail. The second Y-axis driving member is arranged on one side of the second Y-axis slider. The second Y-axis origin sensor is arranged on one side of the second Y-axis driving member. The second Y-axis sensor baffle is fixedly arranged on one side of the second Z-axis slider. The reagent adding head group is respectively arranged on one side of the first Y-axis slider and the second Y-axis slider.
[0006] Wherein, the X-axis driving member includes an X-axis motor mounting plate, an X-axis lead screw motor, and an X-axis lead screw bearing seat. The X-axis motor mounting plate is fixedly connected to the X-axis bottom plate and is located on one side of the X-axis bottom plate. The X-axis lead screw motor is threadedly connected to the X-axis slider and penetrates through the X-axis slider. The X-axis lead screw bearing seat is arranged on one side of the X-axis lead screw motor.
[0007] Wherein, the first Z-axis driving member includes a Z-axis motor mounting plate, a first Z-axis lead screw motor, and a first Z-axis lead screw bearing seat. The Z-axis motor mounting plate is fixedly connected to the Z-axis bottom plate and is located on the top of the Z-axis bottom plate. The first Z-axis lead screw motor is fixedly connected to the Z-axis motor mounting plate and penetrates through the Z-axis motor mounting plate. The first Z-axis lead screw bearing seat is arranged on one side of the first Z-axis lead screw motor.
[0008] Wherein, the second Z-axis driving member includes a second Z-axis lead screw motor and a second Z-axis lead screw bearing seat. The second Z-axis lead screw motor is fixedly connected to the Z-axis motor mounting plate and penetrates through the Z-axis motor mounting plate. The second Z-axis lead screw bearing seat is arranged on one side of the second Z-axis lead screw motor.
[0009] Wherein, the first Y-axis driving member includes a Y-axis motor mounting plate, a first Y-axis lead screw motor, and a first Y-axis lead screw bearing seat. The Y-axis motor mounting plate is fixedly connected to the first Z-axis slider and is located on one side of the first Z-axis slider. The first Y-axis lead screw motor is fixedly connected to the Y-axis motor mounting plate and is located on one side of the Y-axis motor mounting plate. The first Y-axis lead screw bearing seat is arranged on one side of the first Y-axis lead screw motor.
[0010] Wherein, the second Y-axis driving member includes a second Y-axis lead screw motor and a second Y-axis lead screw bearing seat. The second Y-axis lead screw motor is arranged on one side of the second Z-axis slider. The second Y-axis lead screw bearing seat is arranged on one side of the second Y-axis lead screw motor.
[0011] Among them, the reagent sampling head group includes a reagent sampling head, a reagent head fixing member, and a reagent head mounting member. The reagent sampling head includes a reagent sampling head main body, a reagent sampling needle tube, a reagent head cover plate, and a gas joint. The reagent head mounting member is respectively arranged on one side of the first Y-axis slider and the second Y-axis slider. The reagent head fixing member is fixedly connected to the reagent head mounting member and is located at the bottom of the reagent head mounting member. The reagent sampling head main body is arranged on one side of the reagent head fixing member. The reagent sampling needle tube is arranged on the top of the reagent sampling head main body. The reagent head cover plate is arranged on the side of the reagent sampling head main body away from the reagent head fixing member. The gas joint is arranged on the side of the reagent sampling head main body close to the reagent sampling needle tube.
[0012] For the multi-position reagent sampling manipulator of the pathological tissue single-droplet staining system of the present utility model, through the actions of the X-axis module, the first Y-axis module, the second Y-axis module, the first Z-axis module, and the second Z-axis module, the X-axis lateral movement, Y-axis longitudinal movement, and Z-axis vertical lifting of the reagent sampling head group are realized, so as to deliver the reagent sampling head group to the reagent waiting sampling position above the glass slide.
[0013] Specifically, there are two groups of the reagent sampling head group. For the X-axis lateral movement of the reagent sampling head group, when the X-axis driving member is electrified and operates, the X-axis slider slides in the X-axis linear slide rail on the X-axis bottom plate, thereby driving the first Y-axis module, the second Y-axis module, the first Z-axis module, the second Z-axis module, and the reagent sampling head group to move laterally along the X-axis. Furthermore, the reagent sampling head group moves laterally along the X-axis. When the X-axis slider is reset, the X-axis sensor stop piece on the X-axis slider is inserted into the X-axis origin sensor, thereby determining the position of the X-axis slider and limiting the X-axis slider.
[0014] For the Z-axis vertical lifting of the reagent sampling head group, when the first Z-axis driving member and the second Z-axis driving member are electrified and operate, the first Z-axis slider and the second Z-axis slider respectively slide in the first Z-axis linear slide rail and the second Z-axis linear slide rail, thereby driving the first Y-axis module and the second Y-axis module to perform vertical lifting in the Z-axis direction. Furthermore, the reagent sampling head group vertically lifts along the Z-axis. Similarly, the first Z-axis origin sensor and the first Z-axis sensor stop piece, and the second Z-axis origin sensor and the second Z-axis sensor stop piece respectively play a limiting role when the first Z-axis slider and the second Z-axis slider are reset.
[0015] The Y-axis longitudinal movement of the reagent sampling head group is achieved by the energized operation of the first Y-axis drive and the second Y-axis drive, causing the first Y-axis slider and the second Y-axis slider to slide within the first Y-axis linear slide rail and the second Y-axis linear slide rail respectively, thereby driving the two groups of reagent sampling head groups to move longitudinally along the Y-axis. Similarly, the first Y-axis sensor flap and the first Y-axis origin sensor, as well as the second Y-axis sensor flap and the second Y-axis origin sensor, respectively play a limiting role when the first Y-axis slider and the second Y-axis slider are reset;
[0016] The reagent sampling head group is controlled by the reagent liquid path system to perform multi-position and different reagent sampling. Then, through the actions of the X-axis module, the first Y-axis module, the second Y-axis module, the first Z-axis module, and the second Z-axis module, the reagent sampling head group is driven to move above the glass slide, allowing the reagent to cover the entire glass slide. The sampling time is set according to the process requirements to achieve intelligent automation of reagent sampling. The reagent sampling head group can be equipped with multiple sampling heads, and by determining the process positions of reagent dropping, different reagents are dropped respectively to achieve the multi-functionality of the reagent sampling mechanism. The sampling manipulator combines the above six modules together, with a compact structure and small volume, solving the problems of large space occupation and large instrument size of traditional manipulators. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.
[0018] Figure 1 It is a schematic structural diagram of a multi-position reagent sampling manipulator for a pathological tissue single-drop staining system provided by the present invention.
[0019] Figure 2 It is a schematic diagram of the X-axis module.
[0020] Figure 3 It is a schematic diagram of the first Y-axis module.
[0021] Figure 4 It is a schematic diagram of the first Z-axis module.
[0022] Figure 5 It is a schematic diagram of the second Z-axis module.
[0023] Figure 6 It is a schematic diagram of the second Y-axis module.
[0024] Figure 7 It is a schematic diagram of a reagent sampling head group.
[0025] Figure 8 It is a schematic diagram of a reagent sampling head.
[0026] In the figure: 1 - X-axis module, 2 - First Y-axis module, 3 - First Z-axis module, 4 - Second Z-axis module, 5 - Second Y-axis module, 6 - Reagent sampling head group, 101 - X-axis base plate, 102 - X-axis linear slide rail, 103 - X-axis slider, 104 - X-axis sensor baffle, 105 - X-axis origin sensor, 106 - X-axis motor mounting plate, 107 - X-axis lead screw motor, 108 - X-axis lead screw bearing seat, 201 - First Y-axis lead screw bearing seat, 203 - First Y-axis linear slide rail, 204 - First Y-axis slider, 205 - First Y-axis sensor baffle, 206 - First Y-axis origin sensor, 207 - Y-axis motor mounting plate, 208 - First Y-axis lead screw motor, 301 - First Z-axis linear slide rail, 302 - First Z-axis slider, 303 - Z-axis motor mounting plate, 304 - First Z-axis lead screw motor, 305 - First Z-axis origin sensor, 306 - First Z-axis sensor baffle, 307 - Z-axis base plate, 308 - First Z-axis lead screw bearing seat, 402 - Second Z-axis origin sensor, 403 - Second Z-axis sensor baffle, 404 - Second Z-axis lead screw motor, 406 - Second Z-axis slider, 407 - Second Z-axis linear slide rail, 408 - Second Z-axis lead screw bearing seat, 501 - Second Y-axis lead screw motor, 502 - Second Y-axis origin sensor, 503 - Second Y-axis sensor baffle, 504 - Second Y-axis slider, 506 - Second Y-axis linear slide rail, 507 - Second Y-axis lead screw bearing seat, 601 - Reagent sampling head, 602 - Reagent head fixing part, 603 - Reagent head mounting part, 701 - Reagent sampling head main part, 702 - Reagent sampling syringe, 703 - Reagent head cover plate, 704 - Air joint. Detailed implementation manners
[0027] The embodiments of the present invention will be described in detail below. The examples of the embodiments are shown in the drawings, where the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the drawings are exemplary and are intended to explain the present invention and should not be construed as limiting the present invention.
[0028] Please refer to Figures 1 to 5 , the present invention provides a multi-position reagent sampling manipulator for a pathological tissue single-drop staining system, including an X-axis module 1, a first Y-axis module 2, a second Y-axis module 5, a first Z-axis module 3, a second Z-axis module 4 and a reagent sampling head group 6;
[0029] The X-axis module 1 includes an X-axis drive member, an X-axis bottom plate 101, an X-axis linear slide rail 102, an X-axis slider 103, an X-axis sensor flap 104, and an X-axis origin sensor 105. The X-axis linear slide rail 102 is fixedly arranged on the X-axis bottom plate 101. The X-axis slider 103 is arranged on one side of the X-axis linear slide rail 102. The X-axis drive member is arranged on one side of the X-axis slider 103 and the X-axis bottom plate 101. The X-axis origin sensor 105 is arranged on one side of the X-axis drive member. The sensor flap is fixedly arranged on one side of the X-axis slider 103;
[0030] The first Z-axis module 3 includes a first Z-axis drive member, a first Z-axis linear slide rail 301, a first Z-axis slider 302, a first Z-axis origin sensor 305, a first Z-axis sensor flap 306, and a Z-axis bottom plate 307. The second Z-axis module 4 includes a second Z-axis drive member, a second Z-axis linear slide rail 407, a second Z-axis slider 406, a second Z-axis origin sensor 402, and a second Z-axis sensor flap 403. The Z-axis bottom plate 307 is fixedly arranged on the X-axis slider 103. The first Z-axis linear slide rail 301, the second Z-axis linear slide rail 407, the first Z-axis origin sensor 305, and the second Z-axis origin sensor 402 are respectively fixedly arranged on the Z-axis bottom plate 307. The first Z-axis slider 302 is arranged on one side of the first Z-axis linear slide rail 301. The second Z-axis slider 406 is arranged on one side of the second Z-axis linear slide rail 407. The first Z-axis sensor flap 306 is fixedly arranged on one side of the first Z-axis slider 302. The second Z-axis sensor flap 403 is fixedly arranged on one side of the second Z-axis slider 406. The first Z-axis drive member is arranged on one side of the first Z-axis slider 302 and the Z-axis bottom plate 307. The second Z-axis drive member is arranged on one side of the second Z-axis slider 406 and the Z-axis bottom plate 307. The first Z-axis origin sensor 305 is arranged on one side of the first Z-axis drive member. The second Z-axis origin sensor 402 is arranged on one side of the second Z-axis drive member;
[0031] The first Y-axis module 2 includes a first Y-axis drive member, a first Y-axis linear slide rail 203, a first Y-axis slider 204, a first Y-axis sensor flap 205, and a first Y-axis origin sensor 206. The first Y-axis linear slide rail 203 is fixedly arranged on one side of the first Z-axis slider 302. The first Y-axis slider 204 is arranged on one side of the first Y-axis linear slide rail 203. The first Y-axis drive member is arranged on one side of the first Y-axis slider 204. The first Y-axis origin sensor 206 is arranged on one side of the first Y-axis drive member. The first Y-axis sensor flap 205 is fixedly arranged on one side of the first Z-axis slider 302;
[0032] The second Y-axis module 5 includes a second Y-axis drive member, a second Y-axis linear slide rail 506, a second Y-axis slider 504, a second Y-axis sensor flap 503, and a second Y-axis origin sensor 502. The second Y-axis linear slide rail 506 is fixedly arranged on one side of the second Z-axis slider 406. The second Y-axis slider 504 is arranged on one side of the second Y-axis linear slide rail 506. The second Y-axis drive member is arranged on one side of the second Y-axis slider 504. The second Y-axis origin sensor 502 is arranged on one side of the second Y-axis drive member. The second Y-axis sensor flap 503 is fixedly arranged on one side of the second Z-axis slider 406;
[0033] The reagent adding head group 6 is respectively arranged on one side of the first Y-axis slider 204 and the second Y-axis slider 504.
[0034] In this embodiment, through the actions of the X-axis module 1, the first Y-axis module 2, the second Y-axis module 5, the first Z-axis module 3, and the second Z-axis module 4, the X-axis lateral movement, Y-axis longitudinal movement, and Z-axis vertical lifting of the reagent adding head group 6 are realized, so as to deliver the reagent adding head group 6 to the reagent adding position to be sampled above the glass slide;
[0035] Specifically, there are two groups of the reagent adding head group 6. For the X-axis lateral movement of the reagent adding head group 6, the X-axis drive member is energized to operate, so that the X-axis slider 103 slides in the X-axis linear slide rail 102 on the X-axis bottom plate 101, thereby driving the first Y-axis module 2, the second Y-axis module 5, the first Z-axis module 3, the second Z-axis module 4, and the reagent adding head group 6 to move laterally along the X-axis. Furthermore, when the reagent adding head group 6 moves laterally along the X-axis, when the X-axis slider 103 is reset, the X-axis sensor flap 104 on the X-axis slider 103 is inserted into the X-axis origin sensor 105, so as to determine the position of the X-axis slider 103 and limit the X-axis slider 103;
[0036] For the Z-axis vertical lifting of the reagent adding head group 6, by energizing and operating the first Z-axis drive member and the second Z-axis drive member, the first Z-axis slider 302 and the second Z-axis slider 406 slide in the first Z-axis linear slide rail 301 and the second Z-axis linear slide rail 407 respectively, thereby driving the first Y-axis module 2 and the second Y-axis module 5 to perform vertical lifting in the Z-axis direction. Furthermore, the reagent adding head group 6 vertically lifts along the Z-axis. Similarly, the first Z-axis origin sensor 305 and the first Z-axis sensor flap 306, the second Z-axis origin sensor 402 and the second Z-axis sensor flap 403 respectively play a limiting role when the first Z-axis slider 302 and the second Z-axis slider 406 are reset;
[0037] The Y-axis longitudinal movement of the reagent sampling head group 6 is achieved by energizing and operating the first Y-axis driving member and the second Y-axis driving member, causing the first Y-axis slider 204 and the second Y-axis slider 504 to slide within the first Y-axis linear slide rail 203 and the second Y-axis linear slide rail 506 respectively, thereby driving the two groups of reagent sampling head groups 6 to move longitudinally along the Y-axis. Similarly, the first Y-axis sensor baffle 205 and the first Y-axis origin sensor 206, and the second Y-axis sensor baffle 503 and the second Y-axis origin sensor 502 respectively play a limiting role when the first Y-axis slider 204 and the second Y-axis slider 504 are reset;
[0038] The reagent sampling head group 6 is controlled by the reagent liquid path system to perform multi-position and different reagent sampling. Then, through the actions of the X-axis module 1, the first Y-axis module 2, the second Y-axis module 5, the first Z-axis module 3, and the second Z-axis module 4, the reagent sampling head group 6 is driven to move above the glass slide, so that the reagent covers the entire glass slide. The sampling time is set according to the process requirements to achieve intelligent automation of reagent sampling. The reagent sampling head group 6 can be equipped with multiple sampling heads, and different reagents can be respectively dropped by determining the process position of reagent dropping, realizing the multi-function of the reagent sampling mechanism. The sampling manipulator combines the above six modules together, with a compact structure and small volume, solving the problems of large space occupation and large instrument size of traditional manipulators.
[0039] Furthermore, the X-axis driving member includes an X-axis motor mounting plate 106, an X-axis lead screw motor 107, and an X-axis lead screw bearing seat 108. The X-axis motor mounting plate 106 is fixedly connected to the X-axis bottom plate 101 and is located on one side of the X-axis bottom plate 101. The X-axis lead screw motor 107 is threadedly connected to the X-axis slider 103 and penetrates through the X-axis slider 103. The X-axis lead screw bearing seat 108 is disposed on one side of the X-axis lead screw motor 107.
[0040] In this embodiment, the X-axis motor mounting plate 106 provides an installation condition for the X-axis lead screw motor 107. The X-axis lead screw motor 107 is used to drive the X-axis slider 103, causing the X-axis slider 103 to slide within the X-axis linear slide rail 102. The setting of the X-axis lead screw bearing seat 108 is used to limit the X-axis slider 103 to prevent the X-axis slider 103 from falling off.
[0041] Further, the first Z-axis driving member includes a Z-axis motor mounting plate 303, a first Z-axis lead screw motor 304, and a first Z-axis lead screw bearing block 308. The Z-axis motor mounting plate 303 is fixedly connected to the Z-axis bottom plate 307 and is located at the top of the Z-axis bottom plate 307. The first Z-axis lead screw motor 304 is fixedly connected to the Z-axis motor mounting plate 303 and penetrates through the Z-axis motor mounting plate 303. The first Z-axis lead screw bearing block 308 is disposed on one side of the first Z-axis lead screw motor 304.
[0042] In this embodiment, the Z-axis motor mounting plate 303 provides a mounting condition for the X-axis lead screw motor 107. The first Z-axis lead screw motor 304 is used to drive the first Z-axis slider 302 so that the first Z-axis slider 302 slides within the first Z-axis linear slide rail 301. The setting of the first Z-axis lead screw bearing block 308 is used to limit the first Z-axis slider 302 to prevent the first Z-axis slider 302 from falling off.
[0043] Further, the second Z-axis driving member includes a second Z-axis lead screw motor 404 and a second Z-axis lead screw bearing block 408. The second Z-axis lead screw motor 107 is fixedly connected to the Z-axis motor mounting plate 303 and penetrates through the Z-axis motor mounting plate 303. The second Z-axis lead screw bearing block 408 is disposed on one side of the second Z-axis lead screw motor 404.
[0044] In this embodiment, the second Z-axis lead screw motor 404 is used to drive the second Z-axis slider 406 so that the second Z-axis slider 406 slides within the second Z-axis linear slide rail 407. The setting of the second Z-axis lead screw bearing block 408 is used to limit the second Z-axis slider 406 to prevent the second Z-axis slider 406 from falling off.
[0045] Further, the first Y-axis driving member includes a Y-axis motor mounting plate 207, a first Y-axis lead screw motor 208, and a first Y-axis lead screw bearing block 201. The Y-axis motor mounting plate 207 is fixedly connected to the first Z-axis slider 302 and is located on one side of the first Z-axis slider 302. The first Y-axis lead screw motor 208 is fixedly connected to the Y-axis motor mounting plate 207 and is located on one side of the Y-axis motor mounting plate 207. The first Y-axis lead screw bearing block 201 is disposed on one side of the first Y-axis lead screw motor 208.
[0046] In this embodiment, the Y-axis motor mounting plate 207 provides a mounting condition for the first Y-axis lead screw motor 208. The first Y-axis lead screw motor 208 is used to drive the first Y-axis slider 204, so that the first Y-axis slider 204 slides within the first Y-axis linear slide rail 203. The first Y-axis lead screw bearing block 201 is provided to limit the first Y-axis slider 204 and prevent the first Y-axis slider 204 from falling off.
[0047] Further, the second Y-axis driving member includes a second Y-axis lead screw motor 501 and a second Y-axis lead screw bearing block 507. The second Y-axis lead screw motor 501 is disposed on one side of the second Z-axis slider 406, and the second Y-axis lead screw bearing block 507 is disposed on one side of the second Y-axis lead screw motor 501.
[0048] In this embodiment, the second Y-axis driving member has the same structure as the first Y-axis driving member. The second Y-axis lead screw motor 501 is also mounted on the Y-axis motor mounting plate 207. The second Y-axis lead screw motor 501 is used to drive the second Y-axis slider 504, so that the second Y-axis slider 504 slides within the second Y-axis linear slide rail 506.
[0049] Further, the reagent dispensing head group 6 includes a reagent dispensing head 601, a reagent head fixing member 602, and a reagent head mounting member 603. The reagent dispensing head 601 includes a reagent dispensing head main body 701, a reagent dispensing needle tube 702, a reagent head cover plate 703, and a gas joint 704. The reagent head mounting member 603 is respectively disposed on one side of the first Y-axis slider 204 and the second Y-axis slider 504. The reagent head fixing member 602 is fixedly connected to the reagent head mounting member 603 and is located at the bottom of the reagent head mounting member 603. The reagent dispensing head main body 701 is disposed on one side of the reagent head fixing member 602. The reagent dispensing needle tube 702 is disposed on the top of the reagent dispensing head main body 701. The reagent head cover plate 703 is disposed on the side of the reagent dispensing head main body 701 away from the reagent head fixing member 602. The gas joint 704 is disposed on the side of the reagent dispensing head main body 701 close to the reagent dispensing needle tube 702.
[0050] In this embodiment, the reagent head mounting member 603 is used for mounting the reagent head fixing member 602 to the first Y-axis slider 204 and the second Y-axis slider 504. The reagent head fixing member 602 provides an installation condition for the main reagent adding head member 701. The main reagent adding head member 701 is used for adding reagents to the glass slide. The reagent adding syringe 702 is used for adding reagents into the main reagent adding head member 701. The input end of the air connector 704 is connected to an air pipe to introduce compressed air, and the output end is connected to the main reagent adding head member 701. The main reagent adding head member 701 has a rectangular flat groove at the compressed air output part, and forms a flat rectangular air outlet cavity by connecting with the reagent head cover plate 703. The width direction of the air outlet cavity covers the width direction of the glass slide, and is used for outputting compressed air to blow the reagents on the glass slide clean, so as to prevent the reagents at different workstations from remaining on the glass slide, and ensure the accuracy and stability of the staining process.
[0051] The above-disclosed is only the preferred embodiment of the multi-position reagent adding manipulator of the present utility model for the separate dropwise staining system of pathological tissues. Of course, it cannot be used to limit the scope of the rights of the present utility model. Those of ordinary skill in the art can understand all or part of the processes of implementing the above embodiments, and the equivalent changes made according to the claims of the present utility model still fall within the scope covered by the present utility model.
Claims
1. A multi-position reagent adding manipulator for a separate dropping and staining system of pathological tissues, characterized in that it includes an X-axis module, a first Y-axis module, a second Y-axis module, a first Z-axis module, a second Z-axis module and a reagent adding head group; The X-axis module includes an X-axis driving member, an X-axis bottom plate, an X-axis linear slide rail, an X-axis slider, an X-axis sensor stop piece and an X-axis origin sensor. The X-axis linear slide rail is fixedly arranged on the X-axis bottom plate. The X-axis slider is arranged on one side of the X-axis linear slide rail. The X-axis driving member is arranged on one side of the X-axis slider and the X-axis bottom plate. The X-axis origin sensor is arranged on one side of the X-axis driving member. The sensor stop piece is fixedly arranged on one side of the X-axis slider; The first Z-axis module includes a first Z-axis driving member, a first Z-axis linear slide rail, a first Z-axis slider, a first Z-axis origin sensor, a first Z-axis sensor stop piece and a Z-axis bottom plate. The second Z-axis module includes a second Z-axis driving member, a second Z-axis linear slide rail, a second Z-axis slider, a second Z-axis origin sensor and a second Z-axis sensor stop piece. The Z-axis bottom plate is fixedly arranged on the X-axis slider. The first Z-axis linear slide rail, the second Z-axis linear slide rail, the first Z-axis origin sensor and the second Z-axis origin sensor are respectively fixedly arranged on the Z-axis bottom plate. The first Z-axis slider is arranged on one side of the first Z-axis linear slide rail. The second Z-axis slider is arranged on one side of the second Z-axis linear slide rail. The first Z-axis sensor stop piece is fixedly arranged on one side of the first Z-axis slider. The second Z-axis sensor stop piece is fixedly arranged on one side of the second Z-axis slider. The first Z-axis driving member is arranged on one side of the first Z-axis slider and the Z-axis bottom plate. The second Z-axis driving member is arranged on one side of the second Z-axis slider and the Z-axis bottom plate. The first Z-axis origin sensor is arranged on one side of the first Z-axis driving member. The second Z-axis origin sensor is arranged on one side of the second Z-axis driving member; The first Y-axis module includes a first Y-axis driving member, a first Y-axis linear slide rail, a first Y-axis slider, a first Y-axis sensor stop piece and a first Y-axis origin sensor. The first Y-axis linear slide rail is fixedly arranged on one side of the first Z-axis slider. The first Y-axis slider is arranged on one side of the first Y-axis linear slide rail. The first Y-axis driving member is arranged on one side of the first Y-axis slider. The first Y-axis origin sensor is arranged on one side of the first Y-axis driving member. The first Y-axis sensor stop piece is fixedly arranged on one side of the first Z-axis slider; The second Y-axis module includes a second Y-axis driving member, a second Y-axis linear slide rail, a second Y-axis slider, a second Y-axis sensor stop piece and a second Y-axis origin sensor. The second Y-axis linear slide rail is fixedly arranged on one side of the second Z-axis slider. The second Y-axis slider is arranged on one side of the second Y-axis linear slide rail. The second Y-axis driving member is arranged on one side of the second Y-axis slider. The second Y-axis origin sensor is arranged on one side of the second Y-axis driving member. The second Y-axis sensor stop piece is fixedly arranged on one side of the second Z-axis slider; The reagent adding head groups are respectively arranged on one side of the first Y-axis slider and the second Y-axis slider.
2. The multi-position reagent adding manipulator for the pathological tissue single-droplet staining system according to claim 1, wherein the X-axis driving member includes an X-axis motor mounting plate, an X-axis lead screw motor, and an X-axis lead screw bearing seat. The X-axis motor mounting plate is fixedly connected to the X-axis bottom plate and is located on one side of the X-axis bottom plate. The X-axis lead screw motor is threadedly connected to the X-axis slider and penetrates through the X-axis slider. The X-axis lead screw bearing seat is arranged on one side of the X-axis lead screw motor.
3. The multi-position reagent adding manipulator for the pathological tissue single-droplet staining system according to claim 1, wherein the first Z-axis driving member includes a Z-axis motor mounting plate, a first Z-axis lead screw motor, and a first Z-axis lead screw bearing seat. The Z-axis motor mounting plate is fixedly connected to the Z-axis bottom plate and is located on the top of the Z-axis bottom plate. The first Z-axis lead screw motor is fixedly connected to the Z-axis motor mounting plate and penetrates through the Z-axis motor mounting plate. The first Z-axis lead screw bearing seat is arranged on one side of the first Z-axis lead screw motor.
4. The multi-position reagent adding manipulator for the pathological tissue single-droplet staining system according to claim 3, wherein the second Z-axis driving member includes a second Z-axis lead screw motor and a second Z-axis lead screw bearing seat. The second Z-axis lead screw motor is fixedly connected to the Z-axis motor mounting plate and penetrates through the Z-axis motor mounting plate. The second Z-axis lead screw bearing seat is arranged on one side of the second Z-axis lead screw motor.
5. The multi-position reagent adding manipulator for the pathological tissue single-droplet staining system according to claim 1, wherein the first Y-axis driving member includes a Y-axis motor mounting plate, a first Y-axis lead screw motor, and a first Y-axis lead screw bearing seat. The Y-axis motor mounting plate is fixedly connected to the first Z-axis slider and is located on one side of the first Z-axis slider. The first Y-axis lead screw motor is fixedly connected to the Y-axis motor mounting plate and is located on one side of the Y-axis motor mounting plate. The first Y-axis lead screw bearing seat is arranged on one side of the first Y-axis lead screw motor.
6. The multi-position reagent adding manipulator for the pathological tissue single-droplet staining system according to claim 1, wherein the second Y-axis driving member includes a second Y-axis lead screw motor and a second Y-axis lead screw bearing seat. The second Y-axis lead screw motor is arranged on one side of the second Z-axis slider. The second Y-axis lead screw bearing seat is arranged on one side of the second Y-axis lead screw motor.
7. The multi-position reagent adding manipulator for the pathological tissue single-droplet staining system according to claim 1, wherein The reagent sampling head group includes a reagent sampling head, a reagent head fixing member, and a reagent head mounting member. The reagent sampling head includes a reagent sampling head main body, a reagent sampling needle tube, a reagent head cover plate, and a gas joint. The reagent head mounting member is respectively arranged on one side of the first Y-axis slider and the second Y-axis slider. The reagent head fixing member is fixedly connected to the reagent head mounting member and is located at the bottom of the reagent head mounting member. The reagent sampling head main body is arranged on one side of the reagent head fixing member. The reagent sampling needle tube is arranged on the top of the reagent sampling head main body. The reagent head cover plate is arranged on the side of the reagent sampling head main body away from the reagent head fixing member. The gas joint is arranged on the side of the reagent sampling head main body close to the reagent sampling needle tube.