Vacuum blood collection tube for separating mononuclear cells
By introducing a slow-flow anti-splash device and a treatment group structure into the vacuum blood collection tube, the problem of difficulty in separating blood splash and special cells is solved, and a safe and convenient monocyte separation and sampling process is achieved.
Patent Information
- Application Number
- CN202422132658.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-02
- Publication Date
- 2025-07-25
- Estimated Expiration
- 2034-09-02
AI Technical Summary
Existing vacuum blood collection vessels are prone to blood splashing during blood collection, contaminating the environment and posing a risk of infection to operators and the environment, and it is difficult to effectively isolate special cells such as monocytes.
A vacuum blood collection tube is designed to separate monocytes, including a slow-flow anti-splash device, a treatment group and an embedded arc structure. The slow-flow limiting cylinder reduces blood impact, the embedded arc surface reduces label wear, and an anticoagulation layer, a serum separation gel layer and a monocyte separation liquid layer are installed in the blood collection tube to achieve cell separation.
Effectively prevent blood splashing, reduce the risk of contamination, simplify the separation process of monocytes, reduce blood collection vessel damage and sampling errors, and ensure the integrity of blood components.
Smart Images

Figure CN223143511U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of vacuum blood collection tubes, in particular to a vacuum blood collection tube for separating mononuclear cells. Background Technique
[0002] The vacuum blood collection tubes currently used clinically are vacuum negative pressure blood collection tubes, mainly composed of a blood collection tube body and a tube cap. Vacuum blood collection tubes are more convenient and safe than traditional blood collection methods such as syringes in the past, because one person uses one belt, one needle, and one towel, and vacuum blood collection avoids blood cross-infection and blood contamination. Currently, vacuum blood collection tubes are widely used in hospital laboratories, and the application scenarios include biochemical items in the laboratory, immune items in the laboratory, ethanol content detection, etc.
[0003] Currently, the unified understanding of the risk factors and prevention and control measures for hospital blood collection infections at home and abroad is that when performing operations that may cause blood splashing, operators should wear goggles and masks to cut off the blood transmission route. However, such operating specifications only treat the symptoms but not the root cause of the above problems. Even if the operators' self-protection is done well, if the blood in the vacuum blood collection tube splashes out, it will still contaminate the environment in the form of aerosols, etc., posing an infection risk to other staff in the environment. Therefore, the research on preventing blood splashing when opening the vacuum blood collection tube fundamentally is an important research direction in the medical device industry and urgently needs to be developed. Content of the Utility Model
[0004] The purpose of the utility model is to provide a vacuum blood collection tube for separating mononuclear cells to solve the problems raised in the above background technique.
[0005] To achieve the above purpose, the utility model provides the following technical solution: A vacuum blood collection tube for separating mononuclear cells, including a vacuum blood collection tube body, a cap, a slow-flow anti-splash device, and a treatment group. The top of the vacuum blood collection tube body is externally sleeved with a cap, the top of the cap is connected with an operation cap, the inside of the vacuum blood collection tube body is provided with a slow-flow anti-splash device and a treatment group, the slow-flow anti-splash device is located at the top of the treatment group, and the slow-flow anti-splash device includes a slow-flow limiting cylinder, an upper arc surface, and a lower arc surface, and the upper arc surface and the lower arc surface are respectively connected to the top and bottom of the slow-flow limiting cylinder.
[0006] Preferably, shock-absorbing strips are equidistantly arranged in a ring on the outer surface of the vacuum blood collection tube body.
[0007] Preferably, an embedded arc surface is embedded on the surface of the bottom of the vacuum blood collection tube body, and both sides of the embedded arc surface are connected with slow arc connecting surfaces. The setting of the slow arc connecting surfaces prevents the edges of the label from being cut off and affects recording.
[0008] Preferably, an internal thread is connected to the inner surface of the cap, and an external thread matching the internal thread is connected to the outer surface of the top of the vacuum blood collection tube body. There is a good bite force between the internal thread and the external thread, so as to ensure that the operation cap will not fall off from the top of the vacuum blood collection tube body.
[0009] Preferably, a butyl rubber stopper is connected to the middle of the top of the cap. The butyl rubber stopper is connected to the bottom of the operation cap. The surface of the butyl rubber stopper is closely attached to the inner wall of the vacuum blood collection tube body, ensuring good sealing between the butyl rubber stopper and the vacuum blood collection tube body, and there is friction between the butyl rubber stopper and the vacuum blood collection tube body, ensuring that the butyl rubber stopper will not fall off from the vacuum blood collection tube body without external force.
[0010] Preferably, the treatment group includes an anticoagulant layer, a serum separation gel layer and a mononuclear cell separation liquid layer, and the serum separation gel layer is connected between the anticoagulant layer and the mononuclear cell separation liquid layer.
[0011] Preferably, the anticoagulant layer is connected to the top of the serum separation gel layer, and the mononuclear cell separation liquid layer is connected to the bottom of the serum separation gel layer.
[0012] Compared with the prior art, the beneficial effects of the present utility model are:
[0013] (1) For this vacuum blood collection tube for separating mononuclear cells, through the slow-flow anti-splash device provided, the impact between the blood flowing into the vacuum blood collection tube body and the tube wall of the vacuum blood collection tube body is effectively reduced, so as to ensure that the substances in the blood are not damaged to the greatest extent, solving the problem that the substances in the blood are easily damaged when an ordinary vacuum blood collection tube is used for blood collection. And when the butyl rubber stopper is taken away from the top of the vacuum blood collection tube body, when the staff processes the blood, in order to avoid the problem that the blood is pushed out by the atmosphere due to the pressure imbalance in the vacuum blood collection tube body, the structure of the slow-flow limiting cylinder can play a good role in preventing blood splashing, thereby reducing the risk of blood sample contamination and environmental pollution;
[0014] (2) For this vacuum blood collection tube for separating mononuclear cells, through the settings of the anticoagulant layer, the serum separation gel layer and the mononuclear cell separation liquid layer, after blood collection and centrifugation operation, the separation of peripheral blood mononuclear cells can be completed, which is convenient to operate and eliminates secondary contamination, solving the problem that it is very troublesome to separate special cells when an ordinary vacuum blood collection tube encounters special cells;
[0015] (3)This vacuum blood collection tube for separating mononuclear cells, by setting the embedded arc surface and forming an extended wall structure with a cavity inside, and pasting a label inside, reduces the wear of the label and also avoids the sampling error caused by blocking the line of sight when pasting the label on the main body of the vacuum blood collection tube. The setting of the shock-absorbing strip can effectively provide good shock-absorbing and protective effects on the external structure of the vacuum blood collection tube main body, reducing the risk of damage caused by the dropping of the vacuum blood collection tube main body. Moreover, the shock-absorbing strips are arranged at equal intervals around the outer surface of the vacuum blood collection tube main body, without affecting the line of sight during the sampling operation. Description of the Drawings
[0016] Figure 1 is a front view structural schematic diagram of the present utility model;
[0017] Figure 2 is a top view structural schematic diagram of the flow-slowing and splash-proof device of the present utility model;
[0018] Figure 3 is a sectional structural schematic diagram of the treatment group of the present utility model;
[0019] Figure 4 is a top view structural schematic diagram of the connection between the main body of the vacuum blood collection tube and the shock-absorbing strip of the present utility model;
[0020] Figure 5 is a bottom view structural schematic diagram of the connection between the main body of the vacuum blood collection tube and the embedded arc surface of the present utility model.
[0021] In the figure: 1. Main body of the vacuum blood collection tube; 2. Cap; 3. Operation cap; 4. Internal thread; 5. External thread; 6. Butyl rubber stopper; 7. Flow-slowing and splash-proof device; 701. Flow-slowing limiting cylinder; 702. Upper arc surface; 703. Lower arc surface; 8. Treatment group; 801. Anticoagulant layer; 802. Serum separation gel layer; 803. Mononuclear cell separation liquid layer; 9. Shock-absorbing strip; 10. Embedded arc surface; 1001. Slow arc connection surface. Detailed Embodiment
[0022] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.
[0023] Please refer to Figures 1-5, an embodiment provided by the present utility model: a vacuum blood collection tube for separating mononuclear cells, comprising a vacuum blood collection tube body 1, a cap 2, a flow-slowing and splash-proof device 7 and a treatment group 8. A cap 2 is sleeved outside the top of the vacuum blood collection tube body 1, and an operation cap 3 is connected to the top of the cap 2. A flow-slowing and splash-proof device 7 and a treatment group 8 are arranged inside the vacuum blood collection tube body 1. The provided flow-slowing and splash-proof device 7 can effectively slow down the impact between the blood flowing into the vacuum blood collection tube body 1 and the tube wall of the vacuum blood collection tube body 1, thereby ensuring to the greatest extent that the substances in the blood are not damaged, and solving the problem that the substances in the blood are easily damaged during blood collection in a general vacuum blood collection tube;
[0024] The flow-slowing and splash-proof device 7 is located above the treatment group 8. The flow-slowing and splash-proof device 7 includes a flow-slowing limiting cylinder 701, an upper arc surface 702 and a lower arc surface 703. The upper arc surface 702 and the lower arc surface 703 are respectively connected to the top and bottom of the flow-slowing limiting cylinder 701. When the butyl rubber stopper 6 is removed from the top of the vacuum blood collection tube body 1, when the staff processes the blood, to avoid the problem that the blood is pushed out by the atmosphere due to the pressure imbalance in the vacuum blood collection tube body 1, the structural setting of the flow-slowing limiting cylinder 701 can play a good role in preventing blood splashing.
[0025] Vibration damping strips 9 are equidistantly arranged in a ring on the outer surface of the vacuum blood collection tube body 1. The setting of the vibration damping strips 9 can effectively play a good role in vibration damping and protection for the external structure of the vacuum blood collection tube body 1, reducing the risk of damage caused by the vacuum blood collection tube body 1 falling, and the vibration damping strips 9 are equidistantly arranged in a ring on the outer surface of the vacuum blood collection tube body 1, which will not affect the line of sight of the sampling work.
[0026] An embedded arc surface 10 is embedded on the surface of the bottom of the vacuum blood collection tube body 1. Both sides of the embedded arc surface 10 are connected with slow arc connecting surfaces 1001. The setting of the embedded arc surface 10 and forming an extended wall structure of the cavity, by pasting labels inside, reduces the wear of the labels and also avoids the sampling error caused by blocking the line of sight when pasting the labels on the vacuum blood collection tube body 1.
[0027] An internal thread 4 is connected to the inner surface of the cap 2, and an external thread 5 matching the internal thread 4 is connected to the outer surface of the top of the vacuum blood collection tube body 1.
[0028] The middle of the top of the cap 2 is connected with a butyl rubber stopper 6, and the butyl rubber stopper 6 is connected to the bottom of the operation cap 3.
[0029] The treatment group 8 includes an anticoagulant layer 801, a serum separator gel layer 802, and a mononuclear cell separation liquid layer 803. The serum separator gel layer 802 is connected between the anticoagulant layer 801 and the mononuclear cell separation liquid layer 803. The settings of the anticoagulant layer 801, the serum separator gel layer 802, and the mononuclear cell separation liquid layer 803 enable the separation of peripheral blood mononuclear cells to be completed through centrifugation after blood collection, which is convenient to operate and eliminates secondary contamination, solving the problem that it is very troublesome to separate special cells when ordinary vacuum blood collection tubes encounter special cells.
[0030] The anticoagulant layer 801 is connected to the top of the serum separator gel layer 802, and the mononuclear cell separation liquid layer 803 is connected to the bottom of the serum separator gel layer 802.
[0031] When the embodiment of the present application is in use: Since a negative pressure is preset in the vacuum blood collection tube body 1, blood can be automatically collected into the vacuum blood collection tube body 1 through a blood collection needle. When the blood enters the vacuum blood collection tube body 1, it will sequentially pass through the anticoagulant layer 801, the serum separator gel layer 802, and the mononuclear cell separation liquid layer 803, making the separation of peripheral blood mononuclear cells easier. And through the slow-flow anti-splash device 7 provided, it is avoided that the blood impacts the tube wall of the vacuum blood collection tube body 1 and the substances in the blood are damaged, solving the problem that it is very troublesome to separate special cells when ordinary vacuum blood collection tubes encounter special cells. Then, the label marked with the blood is adhered to the inner embedded arc surface 10, which will not prevent observing the blood sampling situation in the vacuum blood collection tube body 1.
Claims
1. A vacuum blood collection tube for separating monocytes, characterized in that, It includes a vacuum blood collection tube body (1), a cap (2), a flow-slowing and splash-proof device (7) and a treatment group (8). A cap (2) is sleeved outside the top of the vacuum blood collection tube body (1). An operation cap (3) is connected to the top of the cap (2). A flow-slowing and splash-proof device (7) and a treatment group (8) are arranged inside the vacuum blood collection tube body (1). The flow-slowing and splash-proof device (7) is located at the top of the treatment group (8). The flow-slowing and splash-proof device (7) includes a flow-slowing limiting cylinder (701), an upper arc surface (702) and a lower arc surface (703). The upper arc surface (702) and the lower arc surface (703) are respectively connected to the top and the bottom of the flow-slowing limiting cylinder (701).
2. The vacuum blood collection tube for separating mononuclear cells according to claim 1, characterized in that: Shock-absorbing strips (9) are equidistantly arranged in a circular shape on the outer surface of the vacuum blood collection tube body (1).
3. The vacuum blood collection tube for separating mononuclear cells according to claim 2, characterized in that: An embedded arc surface (10) is embedded on the surface of the bottom of the vacuum blood collection tube body (1). Both sides of the embedded arc surface (10) are connected with slow arc connection surfaces (1001).
4. A vacuum blood collection tube for separating mononuclear cells according to claim 1, characterized in that: An internal thread (4) is connected to the inner surface of the cap (2). An external thread (5) matching the internal thread (4) is connected to the outer surface of the top of the vacuum blood collection tube body (1).
5. A vacuum blood collection tube for separating monocytes according to claim 4, characterized in that: A butyl rubber stopper (6) is connected to the middle of the top of the cap (2). The butyl rubber stopper (6) is connected to the bottom of the operation cap (3).
6. A vacuum blood collection tube for separating mononuclear cells according to claim 1, characterized in that: The treatment group (8) includes an anticoagulant layer (801), a serum separating gel layer (802) and a mononuclear cell separating liquid layer (803). The serum separating gel layer (802) is connected between the anticoagulant layer (801) and the mononuclear cell separating liquid layer (803).
7. A vacuum blood collection tube for separating monocytes according to claim 6, characterized in that: The anticoagulant layer (801) is connected to the top of the serum separating gel layer (802). The mononuclear cell separating liquid layer (803) is connected to the bottom of the serum separating gel layer (802).