Dewaxing liquid sample adding and cleaning device for pathological tissue independent drop dyeing system

Abstract

The utility model relates to the technical field of medical instruments, in particular to a dewaxing liquid sample adding and cleaning device for a pathological tissue independent drop dyeing system, which comprises a dewaxing liquid sample adding and cleaning X-axis mechanism, a dewaxing liquid sample adding and cleaning Y-axis mechanism and a dewaxing liquid sample adding and cleaning Z-axis mechanism, the dewaxing liquid sample adding and cleaning X-axis mechanism comprises an X-axis driving part and an X-axis guide rail fixing plate, the dewaxing liquid sample adding and cleaning Y-axis mechanism comprises a Y-axis driving part, a Y-axis guide rail fixing plate and a dewaxing liquid blowing head assembly, and the dewaxing liquid sample adding and cleaning Z-axis mechanism comprises a Z-axis driving part and a Z-axis guide rail fixing plate. According to the dewaxing liquid blowing head assembly, left-right, up-down and front-back sample adding cleaning of the dewaxing liquid blowing head assembly is achieved, paraffin and other residues left on the surface of a sample are removed, in the whole dewaxing process, rapid dewaxing and cleaning can be conducted on the tissue sample, and therefore the treatment efficiency of the tissue sample is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, in particular to a dewaxing solution sampling and cleaning device for a separate dropping and staining system of pathological tissues. Background Art

[0002] Paraffin section of pathological tissue is one of the most commonly used sectioning techniques in qualitative analysis such as observing tissue morphology and immunohistochemistry, and is widely used in clinical pathological diagnosis and experimental research. After the paraffin section of pathological tissue is made, in order to observe the pathological tissue, the paraffin of the paraffin section needs to be removed first, that is, dewaxing.

[0003] At present, most of the methods for dewaxing pathological tissue section specimens on the market adopt manual dewaxing, sampling and cleaning methods. When using the manual method for dewaxing, the operator first places the embedded section on a temperature-controlled dewaxing table, and then manually removes the wax block through temperature control and tools. Although this method is effective, it depends on the operator's skills and patience, and the efficiency is low.

[0004] The prior art CN108663255A discloses a fully automatic immunohistochemical staining machine, which drives a sampling mechanism and a spraying and air-drying mechanism to move freely in three-dimensional space through a robotic arm device, so that the pathological tissue on the glass slide in the immunohistochemical staining machine can be automatically sampled, sprayed or air-dried, and then the immunohistochemical staining machine can realize the functions of automatic dewaxing and antigen repair, improving the automation degree of the immunohistochemical staining machine.

[0005] However, when the above staining machine uses a robotic arm for dewaxing, because it is necessary to accurately position, sample and clean the sample, the processing speed is slow. Especially when a large number of samples need to be processed quickly, each operation step of the robotic arm takes a lot of time, which will affect the overall processing efficiency. Summary of the Utility Model

[0006] The purpose of the utility model is to provide a dewaxing solution sampling and cleaning device for a separate dropping and staining system of pathological tissues, which solves the technical problem that when the existing staining machine uses a robotic arm for dewaxing, because it is necessary to accurately position, sample and clean the sample, the processing speed is slow. Especially when a large number of samples need to be processed quickly, each operation step of the robotic arm takes a lot of time, which will affect the overall processing efficiency.

[0007] To achieve the above object, the present utility model provides a dewaxing liquid sampling and cleaning device for a separate dropping and staining system of pathological tissues, including a dewaxing liquid sampling and cleaning X-axis mechanism, a dewaxing liquid sampling and cleaning Y-axis mechanism, and a dewaxing liquid sampling and cleaning Z-axis mechanism. The dewaxing liquid sampling and cleaning X-axis mechanism and the dewaxing liquid sampling and cleaning Y-axis mechanism are both connected to the dewaxing liquid sampling and cleaning Z-axis mechanism;

[0008] The dewaxing liquid sampling and cleaning X-axis mechanism includes an X-axis driving member and an X-axis guide rail fixing plate. The X-axis driving member is used to drive the X-axis guide rail fixing plate to move along the X-axis. The X-axis guide rail fixing plate is located on the side of the X-axis driving member close to the dewaxing liquid sampling and cleaning Z-axis mechanism;

[0009] The dewaxing liquid sampling and cleaning Y-axis mechanism includes a Y-axis driving member, a Y-axis guide rail fixing plate, and a dewaxing liquid blowing head assembly. The Y-axis driving member is used to drive the Y-axis guide rail fixing plate to move along the Y-axis. The Y-axis guide rail fixing plate is located on the side of the Y-axis driving member close to the dewaxing liquid sampling and cleaning Z-axis mechanism. The dewaxing liquid blowing head assembly is arranged outside the Y-axis guide rail fixing plate;

[0010] The dewaxing liquid sampling and cleaning Z-axis mechanism includes a Z-axis driving member and a Z-axis guide rail fixing plate. The Z-axis driving member is used to drive the Z-axis guide rail fixing plate to move along the Z-axis. The Z-axis guide rail fixing plate is connected to the X-axis guide rail fixing plate through a guide rail assembly, and is connected to the Y-axis guide rail fixing plate through the Y-axis driving member, and is located on the side of the X-axis guide rail fixing plate away from the X-axis driving member.

[0011] Among them, the X-axis driving member includes an X-axis motor mounting plate, an X-axis motor, an X-axis motor nut mounting block, a bottom plate, a first X-axis linear guide rail, a second X-axis linear guide rail, a lead screw support seat, and an X-axis bearing. The X-axis motor mounting plate is connected to the X-axis motor. The X-axis motor nut mounting block is connected to the X-axis motor through a nut. The bottom plate is connected to the right side of the X-axis motor mounting plate. The first X-axis linear guide rail and the second X-axis linear guide rail are respectively installed on the upper and lower sides of the bottom plate. The lead screw support seat is installed on the left side of the bottom plate. The X-axis bearing is connected to the lead screw support seat, and the screw rod of the X-axis motor is connected to the X-axis bearing. The X-axis guide rail fixing plate is installed on the upper side of the X-axis motor nut mounting block.

[0012] Among them, the X-axis driving member further includes an X-axis optical coupler baffle, and the X-axis optical coupler baffle is installed on one side of the X-axis motor nut mounting block.

[0013] Among them, the Y-axis driving member includes a Y-axis motor mounting plate, a Y-axis motor, a Y-axis motor connecting plate, a Y-axis motor nut mounting block, a first Y-axis linear guide rail, a second Y-axis linear guide rail, a first Y-axis guide rail mounting plate, a second Y-axis guide rail mounting plate, a first strengthening fixing plate, and a second strengthening fixing plate. The Y-axis motor mounting plate is connected to the Y-axis motor. The Y-axis motor connecting plate is connected to the upper side of the Y-axis motor mounting plate. The Y-axis motor nut mounting block is connected to the Y-axis motor by a nut. The first Y-axis linear guide rail is mounted on the lower side of the first Y-axis guide rail mounting plate. The second Y-axis linear guide rail is mounted on the lower side of the second Y-axis guide rail mounting plate. The first strengthening fixing plate is mounted on the front side of the first Y-axis guide rail mounting plate, and the first strengthening fixing plate is connected to the Z-axis guide rail fixing plate. The second strengthening fixing plate is mounted on the front side of the second Y-axis guide rail mounting plate, and the second strengthening fixing plate is connected to the Z-axis guide rail fixing plate.

[0014] Among them, the dewaxing liquid blowing head assembly includes a first rear fixing plate of the blowing head, a second rear fixing plate of the blowing head, a third rear fixing plate of the blowing head, a left front fixing plate of the blowing head, a front middle fixing plate of the blowing head, a right front fixing plate of the blowing head, a first dewaxing liquid blowing head, a second dewaxing liquid blowing head, a third dewaxing liquid blowing head, a fourth dewaxing liquid blowing head, a fifth dewaxing liquid blowing head, a sixth dewaxing liquid blowing head, a first blowing head cover plate, a second blowing head cover plate, a third blowing head cover plate, a fourth blowing head cover plate, a fifth blowing head cover plate, a sixth blowing head cover plate, a first quick connector, a second quick connector, a third quick connector, a fourth quick connector, a fifth quick connector, a sixth quick connector, a first sampling needle, a second sampling needle, a third sampling needle, a fourth sampling needle, a fifth sampling needle, a sixth sampling needle, a seventh sampling needle, an eighth sampling needle, a ninth sampling needle, a tenth sampling needle, an eleventh sampling needle, and a twelfth sampling needle. The Y-axis guide rail fixing plate and the first rear fixing plate of the blowing head are installed on the left rear side, the Y-axis guide rail fixing plate and the second rear fixing plate of the blowing head are installed on the left middle side, the Y-axis guide rail fixing plate and the third rear fixing plate of the blowing head are installed on the right rear side. The first dewaxing liquid blowing head, the second dewaxing liquid blowing head, and the third dewaxing liquid blowing head are connected to the lower side of the Y-axis guide rail fixing plate through the first rear fixing plate of the blowing head, the second rear fixing plate of the blowing head, and the third rear fixing plate of the blowing head. The left front fixing plate of the blowing head and the Y-axis guide rail fixing plate are installed on the left front side, the front middle fixing plate of the blowing head and the Y-axis guide rail fixing plate are installed in the middle, and the right front fixing plate of the blowing head and the Y-axis guide rail fixing plate are installed on the right front side. The left front fixing plate of the blowing head, the front middle fixing plate of the blowing head, and the right front fixing plate of the blowing head, together with the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head, are installed on the lower side of the Y-axis guide rail fixing plate. The first blowing head cover plate, the second blowing head cover plate, the third blowing head cover plate, the fourth blowing head cover plate, the fifth blowing head cover plate, and the sixth blowing head cover plate are respectively connected to the first dewaxing liquid blowing head, the second dewaxing liquid blowing head, the third dewaxing liquid blowing head, the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head on one side. The first quick connector, the second quick connector, the third quick connector, the fourth quick connector, the fifth quick connector, and the sixth quick connector are respectively connected to the first dewaxing liquid blowing head, the second dewaxing liquid blowing head, the third dewaxing liquid blowing head, the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head. The first sampling needle, the second sampling needle, the third sampling needle, the fourth sampling needle, the fifth sampling needle, the sixth sampling needle, the seventh sampling needle, the eighth sampling needle, the ninth sampling needle, the tenth sampling needle, the eleventh sampling needle, and the twelfth sampling needle are respectively connected to the first dewaxing liquid blowing head, the second dewaxing liquid blowing head, the third dewaxing liquid blowing head, the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head on the front side.

[0015] Among them, the Z-axis driving member includes a Z-axis motor mounting plate, a Z-axis motor, a Z-axis nut connecting plate, a Z-axis bearing support plate and a Z-axis bearing. The Z-axis motor mounting plate is connected to the Z-axis motor. The Z-axis nut connecting plate is connected to the Z-axis motor by a nut. The Z-axis bearing support plate is connected to the Z-axis bearing. The Z-axis nut connecting plate is connected to the Z-axis guide rail fixing plate.

[0016] Among them, the guide rail assembly includes a Z-axis linear guide rail three and a Z-axis linear guide rail four. The Z-axis linear guide rail three and the Z-axis linear guide rail four are respectively slidably connected to the Z-axis guide rail fixing plate and are respectively installed on the left and right sides of the X-axis guide rail fixing plate.

[0017] A dewaxing solution sampling and cleaning device for a pathological tissue separate drip dyeing staining system of the present utility model drives the X-axis guide rail fixing plate to move along the X-axis through the X-axis driving member, so that the Y-axis guide rail fixing plate can be driven to move along the X-axis through the Z-axis guide rail fixing plate, and further drives the dewaxing solution blowing head assembly to move along the X-axis. The Y-axis driving member drives the Y-axis guide rail fixing plate to move along the Y-axis, thereby driving the dewaxing solution blowing head assembly to move along the Y-axis. The Z-axis driving member drives the Z-axis guide rail fixing plate to move along the Z-axis, thereby driving the Y-axis guide rail fixing plate to move along the Z-axis, and further driving the dewaxing solution blowing head assembly to move along the Z-axis. Combining the movement of the dewaxing solution blowing head assembly along the X-axis and the Y-axis, the dewaxing solution blowing head assembly can perform left-right, up-down, and front-back sampling and cleaning, synchronize the operation of two rows of sampling and cleaning test piece racks, so that the tissue specimen can be dewaxed and cleaned with dewaxing solution to remove paraffin and other residues remaining on the sample surface. During the entire dewaxing process, the tissue specimen can be quickly dewaxed and cleaned, thereby improving the processing efficiency of the tissue specimen, and solving the technical problem that when the existing staining machine uses a robotic arm for dewaxing, because precise positioning, sampling, and cleaning of the sample are required, the processing speed is slow. Especially when a large number of samples need to be quickly processed, each operation step of the robotic arm requires a lot of time, which will affect the overall processing efficiency. Description of the Drawings

[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art.

[0019] Figure 1 It is a schematic structural diagram of the overall dewaxing solution sampling and cleaning device for a pathological tissue separate drip dyeing staining system according to the first embodiment of the present utility model.

[0020] Figure 2It is a schematic structural diagram of the X-axis mechanism for adding and cleaning dewaxing liquid in the first embodiment of the present utility model.

[0021] Figure 3 It is an exploded view of the X-axis mechanism for adding and cleaning dewaxing liquid in the first embodiment of the present utility model.

[0022] Figure 4 It is a schematic structural diagram of the Y-axis mechanism for adding and cleaning dewaxing liquid in the first embodiment of the present utility model.

[0023] Figure 5 It is an exploded Figure 1 .

[0024] Figure 6 It is an exploded Figure 2 .

[0025] Figure 7 It is a schematic structural diagram of the Z-axis mechanism for adding and cleaning dewaxing liquid in the first embodiment of the present utility model.

[0026] In the figure: 1 - Dewaxing liquid sampling and cleaning X-axis mechanism, 2 - Dewaxing liquid sampling and cleaning Y-axis mechanism, 3 - Dewaxing liquid sampling and cleaning Z-axis mechanism, 101 - X-axis motor mounting plate, 102 - X-axis motor, 103 - X-axis motor nut mounting block, 104 - Base plate, 105 - X-axis linear guide rail 1, 106 - X-axis linear guide rail 2, 107 - Lead screw support seat, 108 - X-axis bearing, 109 - X-axis optical coupler baffle, 110 - X-axis guide rail fixing plate, 111 - Z-axis linear guide rail 3, 112 - Z-axis linear guide rail 4, 201 - Y-axis motor mounting plate, 202 - Y-axis motor, 203 - Y-axis sensor, 204 - Y-axis motor connecting plate, 205 - Y-axis motor nut mounting block, 206 - Y-axis optical coupler baffle, 207 - Y-axis linear guide rail 1, 208 - Y-axis guide rail mounting plate 1, 209 - Y-axis linear guide rail 2, 210 - Y-axis guide rail mounting plate 2, 211 - Reinforcing fixing plate 1, 212 - Reinforcing fixing plate 2, 213 - Y-axis guide rail fixing plate, 214 - Blowing head rear fixing plate 1, 215 - Blowing head rear fixing plate 2, 216 - Blowing head rear fixing plate 3, 217 - Dewaxing liquid blowing head 1, 218 - Dewaxing liquid blowing head 2, 219 - Dewaxing liquid blowing head 3, 220 - Blowing head left front fixing plate, 221 - Blowing head front middle fixing plate, 222 - Blowing head right front fixing plate, 223 - Dewaxing liquid blowing head 4, 224 - Dewaxing liquid blowing head 5, 225 - Dewaxing liquid blowing head 6, 226 - Blowing head cover plate 1, 227 - Blowing head cover plate 2, 228 - Blowing head cover plate 3, 229 - Blowing head cover plate 4, 230 - Blowing head cover plate 5, 231 - Blowing head cover plate 6, 232 - Quick connector 1, 233 - Quick connector 2, 234 - Quick connector 3, 235 - Quick connector 4, 236 - Quick connector 5, 237 - Quick connector 6, 238 - Sampling needle 1, 239 - Sampling needle 2, 240 - Sampling needle 3, 241 - Sampling needle 4, 242 - Sampling needle 5, 243 - Sampling needle 6, 244 - Sampling needle 7, 245 - Sampling needle 8, 246 - Sampling needle 9, 247 - Sampling needle 10, 248 - Sampling needle 11, 249 - Sampling needle 12, 301 - Z-axis motor mounting plate, 302 - Z-axis motor, 303 - Z-axis nut connecting plate, 304 - Z-axis bearing support plate, 305 - Z-axis bearing, 306 - Z-axis optical coupler baffle, 307 - Z-axis sensor, 308 - Z-axis optical coupler mounting plate, 309 - Z-axis guide rail fixing plate. Detailed implementation manners

[0027] The following details the embodiments of the present invention. The examples of the embodiments are shown in the drawings. The embodiments described below with reference to the drawings are exemplary and are intended to explain the present invention, and should not be construed as a limitation to the present invention.

[0028] First embodiment:

[0029] Please refer toFigures 1 to 7 , the utility model provides a dewaxing liquid sampling and cleaning device for a separate dropping and staining system of pathological tissues, which includes a dewaxing liquid sampling and cleaning X-axis mechanism 1, a dewaxing liquid sampling and cleaning Y-axis mechanism 2, and a dewaxing liquid sampling and cleaning Z-axis mechanism 3. The dewaxing liquid sampling and cleaning X-axis mechanism 1 includes an X-axis driving member and an X-axis guide rail fixing plate 110. The X-axis driving member includes an X-axis motor mounting plate 101, an X-axis motor 102, an X-axis motor nut mounting block 103, a bottom plate 104, an X-axis linear guide rail 105, an X-axis linear guide rail 106, a lead screw support seat 107, an X-axis bearing 108, and an X-axis optical coupler baffle 109. The dewaxing liquid sampling and cleaning Y-axis mechanism 2 includes a Y-axis driving member, a Y-axis guide rail fixing plate 213, and a dewaxing liquid blowing head assembly. The Y-axis driving member includes a Y-axis motor mounting plate 201, a Y-axis motor 202, a Y-axis motor connecting plate 204, a Y-axis motor nut mounting block 205, a Y-axis linear guide rail 207, a Y-axis linear guide rail 209, a Y-axis guide rail mounting plate 208, a Y-axis guide rail mounting plate 210, a strengthening fixing plate 211, a strengthening fixing plate 212, a Y-axis sensor 203, and a Y-axis optical coupler baffle 206. The dewaxing liquid blowing head assembly includes a blowing head rear fixing plate 214, a blowing head rear fixing plate 215, a blowing head rear fixing plate 216, a blowing head left front fixing plate 220, a blowing head front middle fixing plate 221, a blowing head right front fixing plate 222, a dewaxing liquid blowing head 217, a dewaxing liquid blowing head 218, a dewaxing liquid blowing head 219, a dewaxing liquid blowing head 223, a dewaxing liquid blowing head 224, a dewaxing liquid blowing head 225, a blowing head cover plate 226, a blowing head cover plate 227, a blowing head cover plate 228, a blowing head cover plate 229, a blowing head cover plate 230, a blowing head cover plate 231, a quick connector 232, a quick connector 233, a quick connector 234, a quick connector 235, a quick connector 236, a quick connector 237, a sampling needle 238, a sampling needle 239, a sampling needle 240, a sampling needle 241, a sampling needle 242, a sampling needle 243, a sampling needle 244, a sampling needle 245, a sampling needle 246, a sampling needle 247, a sampling needle 248, and a sampling needle 249. The dewaxing liquid sampling and cleaning Z-axis mechanism 3 includes a Z-axis driving member and a Z-axis guide rail fixing plate 309. The Z-axis driving member includes a Z-axis motor mounting plate 301, a Z-axis motor 302, a Z-axis nut connecting plate 303, a Z-axis bearing support plate 304, a Z-axis bearing 305, a Z-axis optical coupler baffle 306, a Z-axis sensor 307, and a Z-axis optical coupler mounting plate 308. The guide rail assembly includes a Z-axis linear guide rail 111 and a Z-axis linear guide rail 112.

[0030] In this embodiment, the X-axis driving member drives the X-axis guide rail fixing plate 110 to move along the X-axis, so that the Y-axis guide rail fixing plate 213 can be driven by the Z-axis guide rail fixing plate 309 to move along the X-axis, and further drive the dewaxing liquid blowing head assembly to move along the X-axis. The Y-axis driving member drives the Y-axis guide rail fixing plate 213 to move along the Y-axis, so as to drive the dewaxing liquid blowing head assembly to move along the Y-axis. The Z-axis driving member drives the Z-axis guide rail fixing plate 309 to move along the Z-axis, so as to drive the Y-axis guide rail fixing plate 213 to move along the Z-axis, and further drive the dewaxing liquid blowing head assembly to move along the Z-axis. Combining the movement of the dewaxing liquid blowing head assembly along the X-axis and the Y-axis, the dewaxing liquid blowing head assembly can perform sample addition and cleaning in the left-right, up-down, and front-back directions, synchronize the work of two rows of sample addition and cleaning test piece racks, so that the tissue specimen can be dewaxed and cleaned with the dewaxing liquid to remove paraffin and other residues remaining on the surface of the sample. During the entire dewaxing process, the tissue specimen can be quickly dewaxed and cleaned, thereby improving the processing efficiency of the tissue specimen, and solving the technical problem that when the existing staining machine uses a robotic arm for dewaxing, because precise positioning, sample addition, and cleaning of the sample are required, the processing speed is slow. Especially when a large number of samples need to be processed quickly, each operation step of the robotic arm takes a lot of time, which will affect the overall processing efficiency.

[0031] Wherein, the dewaxing liquid sample addition and cleaning X-axis mechanism 1 and the dewaxing liquid sample addition and cleaning Y-axis mechanism 2 are both connected to the dewaxing liquid sample addition and cleaning Z-axis mechanism 3. The X-axis driving member is used to drive the X-axis guide rail fixing plate 110 to move along the X-axis. The X-axis guide rail fixing plate 110 is located on the side of the X-axis driving member close to the dewaxing liquid sample addition and cleaning Z-axis mechanism 3. The Y-axis driving member is used to drive the Y-axis guide rail fixing plate 213 to move along the Y-axis. The Y-axis guide rail fixing plate 213 is located on the side of the Y-axis driving member close to the dewaxing liquid sample addition and cleaning Z-axis mechanism 3. The dewaxing liquid blowing head assembly is arranged outside the Y-axis guide rail fixing plate 213. The Z-axis driving member is used to drive the Z-axis guide rail fixing plate 309 to move along the Z-axis. The Z-axis guide rail fixing plate 309 is connected to the X-axis guide rail fixing plate 110 through a guide rail assembly, and is connected to the Y-axis guide rail fixing plate 213 through the Y-axis driving member, and is located on the side of the X-axis guide rail fixing plate 110 away from the X-axis driving member.

[0032] Secondly, the X-axis motor mounting plate 101 is connected to the X-axis motor 102. The X-axis motor nut mounting block 103 is connected to the X-axis motor 102 by a nut. The bottom plate 104 is connected to the right side of the X-axis motor mounting plate 101. The first X-axis linear guide 105 and the second X-axis linear guide 106 are respectively installed on the upper and lower sides of the bottom plate 104. The lead screw support base 107 is installed on the left side of the bottom plate 104. The X-axis bearing 108 is connected to the lead screw support base 107, and the screw of the X-axis motor 102 is connected to the X-axis bearing 108. The X-axis guide fixing plate 110 is installed on the upper side of the X-axis motor nut mounting block 103. The X-axis opto-coupler baffle 109 is installed on one side of the X-axis motor nut mounting block 103.

[0033] Thirdly, the Y-axis motor mounting plate 201 is connected to the Y-axis motor 202. The Y-axis motor connecting plate 204 is connected to the upper side of the Y-axis motor mounting plate 201. The Y-axis motor nut mounting block 205 is connected to the Y-axis motor 202 by a nut. The first Y-axis linear guide 207 is installed on the lower side of the first Y-axis guide mounting plate 208. The second Y-axis linear guide 209 is installed on the lower side of the second Y-axis guide mounting plate 210. The first reinforcing fixing plate 211 is installed on the front side of the first Y-axis guide mounting plate 208, and the first reinforcing fixing plate 211 is connected to the Z-axis guide fixing plate 309. The second reinforcing fixing plate 212 is installed on the front side of the second Y-axis guide mounting plate 210, and the second reinforcing fixing plate 212 is connected to the Z-axis guide fixing plate 309. The Y-axis sensor 203 is installed on the upper side of the Y-axis motor mounting plate 201. The Y-axis opto-coupler baffle 206 is connected to the upper side of the Y-axis motor nut mounting block.

[0034] Meanwhile, the Y-axis guide rail fixing plate 213 and the first post-fixing plate of the blowing head 214 are installed at the left rear side, the Y-axis guide rail fixing plate 213 and the second post-fixing plate of the blowing head 215 are installed at the left middle side, the Y-axis guide rail fixing plate 213 and the third post-fixing plate of the blowing head 216 are installed at the right rear side. The first dewaxing liquid blowing head 217, the second dewaxing liquid blowing head 218, the third dewaxing liquid blowing head 219 and the first, second and third post-fixing plates of the blowing head 214, 215, 216 are connected to the lower side of the Y-axis guide rail fixing plate 213. The left front fixing plate of the blowing head 220 and the Y-axis guide rail fixing plate 213 are installed at the left front side, the middle front fixing plate of the blowing head 221 and the Y-axis guide rail fixing plate 213 are installed in the middle, and the right front fixing plate of the blowing head 222 and the Y-axis guide rail fixing plate 213 are installed at the right front side. The left front fixing plate of the blowing head 220, the middle front fixing plate of the blowing head 221, the right front fixing plate of the blowing head 222 and the fourth dewaxing liquid blowing head 223, the fifth dewaxing liquid blowing head 224, the sixth dewaxing liquid blowing head 225 are installed at the lower side of the Y-axis guide rail fixing plate 213. The first blowing head cover plate 226, the second blowing head cover plate 227, the third blowing head cover plate 228, the fourth blowing head cover plate 229, the fifth blowing head cover plate 230, the sixth blowing head cover plate 231 are respectively connected to the first dewaxing liquid blowing head 217, the second dewaxing liquid blowing head 218, the third dewaxing liquid blowing head 219, the fourth dewaxing liquid blowing head 223, the fifth dewaxing liquid blowing head 224, the sixth dewaxing liquid blowing head 225 on one side. The first quick connector 232, the second quick connector 233, the third quick connector 234, the fourth quick connector 235, the fifth quick connector 236, the sixth quick connector 237 are respectively connected to the first dewaxing liquid blowing head 217, the second dewaxing liquid blowing head 218, the third dewaxing liquid blowing head 219, the fourth dewaxing liquid blowing head 223, the fifth dewaxing liquid blowing head 224, the sixth dewaxing liquid blowing head 225. The first sampling needle 238, the second sampling needle 239, the third sampling needle 240, the fourth sampling needle 241, the fifth sampling needle 242, the sixth sampling needle 243, the seventh sampling needle 244, the eighth sampling needle 245, the ninth sampling needle 246, the tenth sampling needle 247, the eleventh sampling needle 248, the twelfth sampling needle 249 are respectively connected to the first dewaxing liquid blowing head 217, the second dewaxing liquid blowing head 218, the third dewaxing liquid blowing head 219, the fourth dewaxing liquid blowing head 223, the fifth dewaxing liquid blowing head 224, the sixth dewaxing liquid blowing head 225 and installed at the front side.

[0035] In addition, the Z-axis motor mounting plate 301 is connected to the Z-axis motor 302. The Z-axis nut connecting plate 303 is connected to the Z-axis motor 302 by a nut. The Z-axis bearing support plate 304 is connected to the Z-axis bearing 305. The Z-axis nut connecting plate 303 is connected to the Z-axis guide rail fixing plate 309. The Z-axis opto-coupler baffle 306 is connected to the left side of the Z-axis nut connecting plate 303. The Z-axis sensor 307 is connected to the Z-axis opto-coupler mounting plate 308. The Z-axis opto-coupler mounting plate 308 is mounted on the left side of the Z-axis motor mounting plate 301.

[0036] Finally, the Z-axis linear guide rail three 111 and the Z-axis linear guide rail four 112 are respectively slidably connected to the Z-axis guide rail fixing plate 309 and are respectively mounted on the left and right sides of the X-axis guide rail fixing plate 110.

[0037] When using the dewaxing liquid sampling and cleaning device of a pathological tissue separate dropping and staining system according to this embodiment, since the lead screw nut of the X-axis motor 102 is connected to the X-axis motor 102 nut fixing block, and the X-axis linear guide rail one 105 and the X-axis linear guide rail two 106 are respectively connected to the X-axis motor 102 nut fixing block. When the X-axis motor 102 is started, the rotation of the output shaft of the X-axis motor 102 drives the X-axis motor 102 nut fixing block to perform a reciprocating motion left and right outside the output shaft of the X-axis motor 102. Thus, the X-axis motor 102 nut fixing block will perform a reciprocating motion left and right outside the X-axis linear guide rail one 105 and the X-axis linear guide rail two 106, and further drive the X-axis guide rail fixing plate 110 to perform a reciprocating motion left and right outside the X-axis linear guide rail one 105 and the X-axis linear guide rail two 106.

[0038] Since the Z-axis guide rail fixing plate 309 is connected to the Z-axis nut connecting plate 303, and the Z-axis linear guide rail three 111 and the Z-axis linear guide rail four 112 are respectively slidably connected to both sides of the Z-axis guide rail fixing plate 309. The Z-axis motor mounting plate 301 is connected to the Z-axis guide rail fixing plate 309, and the Z-axis motor 302 is connected to the Z-axis motor mounting plate 301. When the Z-axis motor 302 is started, the rotation of the output shaft of the Z-axis motor 302 drives the Z-axis motor mounting plate 301 to perform a reciprocating motion up and down outside the output shaft of the Z-axis motor 302, thereby driving the Z-axis guide rail fixing plate 309 to perform a reciprocating motion up and down outside the Z-axis linear guide rail three 111 and the Z-axis linear guide rail four 112.

[0039] Since the rear fixing plate 1 of the blowing head 214, the rear fixing plate 2 of the blowing head 215, the rear fixing plate 3 of the blowing head 216, the left front fixing plate 220 of the blowing head, the front middle fixing plate 221 of the blowing head, and the right front fixing plate 222 of the blowing head are respectively connected to the first dewaxing liquid blowing head 217, the second dewaxing liquid blowing head 218, the third dewaxing liquid blowing head 219, the fourth dewaxing liquid blowing head 223, the fifth dewaxing liquid blowing head 224, and the sixth dewaxing liquid blowing head 225, the Y-axis guide rail fixing plate 213 is connected to the dewaxing liquid blowing head assembly at both ends on the left, middle, and right sides, and both the first Y-axis linear guide rail 207 and the second Y-axis linear guide rail 209 are connected to the Y-axis guide rail fixing plate 213. The Y-axis motor nut mounting block 205 is connected to the Y-axis guide rail fixing plate 213. The Y-axis motor 202 is respectively connected to the first Y-axis motor mounting plate 201 and the second Y-axis guide rail mounting plate 210 and is mounted on the Y-axis motor connecting plate 204. When the Y-axis motor 202 is started, the rotation of the output shaft of the Y-axis motor 202 drives the first Y-axis motor mounting plate 201 and the second Y-axis guide rail mounting plate 210 to perform reciprocating motion back and forth on the output shaft of the Y-axis motor 202, thereby driving the Y-axis guide rail fixing plate 213 to perform reciprocating motion back and forth, and further driving the dewaxing liquid blowing head assembly to perform reciprocating motion back and forth.

[0040] Since the Z-axis guide rail fixing plate 309 is connected to the X-axis guide rail fixing plate 110 and is connected to the Y-axis guide rail fixing plate 213, the reciprocating transmission of the X-axis guide rail fixing plate 110 left and right outside the first X-axis linear guide rail 105 and the second X-axis linear guide rail 106 can drive the Y-axis guide rail fixing plate 213 to perform reciprocating motion left and right, thereby driving the dewaxing liquid blowing head assembly to perform reciprocating motion left and right. At the same time, the reciprocating motion of the Z-axis guide rail fixing plate 309 up and down outside the third Z-axis linear guide rail 111 and the fourth Z-axis linear guide rail 112 can drive the Y-axis guide rail fixing plate 213 to perform reciprocating motion up and down, thereby driving the dewaxing liquid blowing head assembly to perform reciprocating motion up and down. Combining the left and right reciprocating motion and the front and back reciprocating motion of the dewaxing liquid blowing head assembly, the dewaxing liquid blowing head assembly can perform left and right, up and down, and front and back motions, so that the first dewaxing liquid blowing head 217, the second dewaxing liquid blowing head 218, the third dewaxing liquid blowing head 219, the fourth dewaxing liquid blowing head 223, the fifth dewaxing liquid blowing head 224, and the sixth dewaxing liquid blowing head 225 can perform sample addition and cleaning in a left and right, up and down, and front and back manner, ensuring that two rows of test piece racks can be sampled and cleaned. The blowing head is installed with a sample addition needle to accurately drop the reagent. The blowing head cover plate plays a role in ensuring no air leakage during blowing, effectively blowing away the wax dots on the glass slide.

[0041] In summary, the X-axis driving member drives the X-axis guide rail fixing plate 110 to move along the X-axis, so that the Y-axis guide rail fixing plate 213 can be driven by the Z-axis guide rail fixing plate 309 to move along the X-axis, and then the dewaxing liquid blowing head assembly is driven to move along the X-axis. The Y-axis driving member drives the Y-axis guide rail fixing plate 213 to move along the Y-axis, thereby driving the dewaxing liquid blowing head assembly to move along the Y-axis. The Z-axis driving member drives the Z-axis guide rail fixing plate 309 to move along the Z-axis, so that the Y-axis guide rail fixing plate 213 is driven to move along the Z-axis, and then the dewaxing liquid blowing head assembly is driven to move along the Z-axis. Combining the movement of the dewaxing liquid blowing head assembly along the X-axis and the Y-axis, the dewaxing liquid blowing head assembly can perform sample adding and cleaning in the left-right, up-down, and front-back directions, synchronize the operation of two rows of sample adding and cleaning test piece racks, and thus the tissue specimen can be dewaxed and cleaned with the dewaxing liquid to remove paraffin and other residues remaining on the surface of the sample. During the entire dewaxing process, the tissue specimen can be quickly dewaxed and cleaned, thereby improving the processing efficiency of the tissue specimen, and solving the technical problem that when the existing staining machine uses a robotic arm for dewaxing, because precise positioning, sample adding, and cleaning of the sample are required, the processing speed is slow. Especially when a large number of samples need to be quickly processed, each operation step of the robotic arm takes a lot of time, which will affect the overall processing efficiency.

[0042] The above-disclosed are only one or more preferred embodiments of the present application, and the scope of rights of the present application cannot be limited thereby. Those of ordinary skill in the art can understand the entire or partial processes of implementing the above embodiments, and the equivalent changes made according to the claims of the present application still fall within the scope covered by the present application.

Claims

1. A dewaxing liquid sampling and cleaning device for a separate dripping and staining system of pathological tissues, characterized in that it includes a dewaxing liquid sampling and cleaning X-axis mechanism, a dewaxing liquid sampling and cleaning Y-axis mechanism and a dewaxing liquid sampling and cleaning Z-axis mechanism, and the dewaxing liquid sampling and cleaning X-axis mechanism and the dewaxing liquid sampling and cleaning Y-axis mechanism are both connected to the dewaxing liquid sampling and cleaning Z-axis mechanism; The dewaxing liquid sampling and cleaning X-axis mechanism includes an X-axis driving member and an X-axis guide rail fixing plate. The X-axis driving member is used to drive the X-axis guide rail fixing plate to move along the X-axis, and the X-axis guide rail fixing plate is located on the side of the X-axis driving member close to the dewaxing liquid sampling and cleaning Z-axis mechanism; The dewaxing liquid sampling and cleaning Y-axis mechanism includes a Y-axis driving member, a Y-axis guide rail fixing plate and a dewaxing liquid blowing head assembly. The Y-axis driving member is used to drive the Y-axis guide rail fixing plate to move along the Y-axis, and the Y-axis guide rail fixing plate is located on the side of the Y-axis driving member close to the dewaxing liquid sampling and cleaning Z-axis mechanism. The dewaxing liquid blowing head assembly is arranged outside the Y-axis guide rail fixing plate; The dewaxing liquid sampling and cleaning Z-axis mechanism includes a Z-axis driving member and a Z-axis guide rail fixing plate. The Z-axis driving member is used to drive the Z-axis guide rail fixing plate to move along the Z-axis. The Z-axis guide rail fixing plate is connected to the X-axis guide rail fixing plate through a guide rail assembly and is connected to the Y-axis guide rail fixing plate through the Y-axis driving member, and is located on the side of the X-axis guide rail fixing plate away from the X-axis driving member.

2. The dewaxing liquid sampling and cleaning device for a separate dripping and staining system of pathological tissues according to claim 1, characterized in that the X-axis driving member includes an X-axis motor mounting plate, an X-axis motor, an X-axis motor nut mounting block, a bottom plate, a first X-axis linear guide rail, a second X-axis linear guide rail, a lead screw support seat and an X-axis bearing. The X-axis motor mounting plate is connected to the X-axis motor. The X-axis motor nut mounting block is connected to the X-axis motor through a nut. The bottom plate is connected to the right side of the X-axis motor mounting plate. The first X-axis linear guide rail and the second X-axis linear guide rail are respectively installed on the upper and lower sides of the bottom plate. The lead screw support seat is installed on the left side of the bottom plate. The X-axis bearing is connected to the lead screw support seat, and the screw of the X-axis motor is connected to the X-axis bearing. The X-axis guide rail fixing plate is installed on the upper side of the X-axis motor nut mounting block.

3. The dewaxing liquid sampling and cleaning device for a separate dripping and staining system of pathological tissues according to claim 2, characterized in that the X-axis driving member further includes an X-axis optical coupler baffle, and the X-axis optical coupler baffle is installed on one side of the X-axis motor nut mounting block.

4. The dewaxing liquid sampling and cleaning device for a separate dripping and staining system of pathological tissues according to claim 1, characterized in that The Y-axis driving member includes a Y-axis motor mounting plate, a Y-axis motor, a Y-axis motor connecting plate, a Y-axis motor nut mounting block, a first Y-axis linear guide rail, a second Y-axis linear guide rail, a first Y-axis guide rail mounting plate, a second Y-axis guide rail mounting plate, a first strengthening fixing plate, and a second strengthening fixing plate. The Y-axis motor mounting plate is connected to the Y-axis motor. The Y-axis motor connecting plate is connected to the upper side of the Y-axis motor mounting plate. The Y-axis motor nut mounting block is connected to the Y-axis motor by a nut. The first Y-axis linear guide rail is mounted on the lower side of the first Y-axis guide rail mounting plate. The second Y-axis linear guide rail is mounted on the lower side of the second Y-axis guide rail mounting plate. The first strengthening fixing plate is mounted on the front side of the first Y-axis guide rail mounting plate, and the first strengthening fixing plate is connected to the Z-axis guide rail fixing plate. The second strengthening fixing plate is mounted on the front side of the second Y-axis guide rail mounting plate, and the second strengthening fixing plate is connected to the Z-axis guide rail fixing plate.

5. The dewaxing liquid sampling and cleaning device for the pathological tissue single-drop dyeing staining system according to claim 4, wherein The dewaxing liquid blowing head assembly includes a first rear fixing plate of the blowing head, a second rear fixing plate of the blowing head, a third rear fixing plate of the blowing head, a left front fixing plate of the blowing head, a front middle fixing plate of the blowing head, a right front fixing plate of the blowing head, a first dewaxing liquid blowing head, a second dewaxing liquid blowing head, a third dewaxing liquid blowing head, a fourth dewaxing liquid blowing head, a fifth dewaxing liquid blowing head, a sixth dewaxing liquid blowing head, a first blowing head cover plate, a second blowing head cover plate, a third blowing head cover plate, a fourth blowing head cover plate, a fifth blowing head cover plate, a sixth blowing head cover plate, a first quick connector, a second quick connector, a third quick connector, a fourth quick connector, a fifth quick connector, a sixth quick connector, a first sampling needle, a second sampling needle, a third sampling needle, a fourth sampling needle, a fifth sampling needle, a sixth sampling needle, a seventh sampling needle, an eighth sampling needle, a ninth sampling needle, a tenth sampling needle, an eleventh sampling needle, and a twelfth sampling needle. The Y-axis guide rail fixing plate and the first rear fixing plate of the blowing head are installed on the left rear side. The Y-axis guide rail fixing plate and the second rear fixing plate of the blowing head are installed on the left middle side. The Y-axis guide rail fixing plate and the third rear fixing plate of the blowing head are installed on the right rear side. The first dewaxing liquid blowing head, the second dewaxing liquid blowing head, and the third dewaxing liquid blowing head are connected to the lower side of the Y-axis guide rail fixing plate with the first rear fixing plate of the blowing head, the second rear fixing plate of the blowing head, and the third rear fixing plate of the blowing head. The left front fixing plate of the blowing head and the Y-axis guide rail fixing plate are installed on the left front side. The front middle fixing plate of the blowing head and the Y-axis guide rail fixing plate are installed in the middle. The right front fixing plate of the blowing head and the Y-axis guide rail fixing plate are installed on the right front side. The left front fixing plate of the blowing head, the front middle fixing plate of the blowing head, and the right front fixing plate of the blowing head, together with the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head, are installed on the lower side of the Y-axis guide rail fixing plate. The first blowing head cover plate, the second blowing head cover plate, the third blowing head cover plate, the fourth blowing head cover plate, the fifth blowing head cover plate, and the sixth blowing head cover plate are respectively connected to the first dewaxing liquid blowing head, the second dewaxing liquid blowing head, the third dewaxing liquid blowing head, the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head on one side. The first quick connector, the second quick connector, the third quick connector, the fourth quick connector, the fifth quick connector, and the sixth quick connector are respectively connected to the first dewaxing liquid blowing head, the second dewaxing liquid blowing head, the third dewaxing liquid blowing head, the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head. The first sampling needle, the second sampling needle, the third sampling needle, the fourth sampling needle, the fifth sampling needle, the sixth sampling needle, the seventh sampling needle, the eighth sampling needle, the ninth sampling needle, the tenth sampling needle, the eleventh sampling needle, and the twelfth sampling needle are respectively connected to the first dewaxing liquid blowing head, the second dewaxing liquid blowing head, the third dewaxing liquid blowing head, the fourth dewaxing liquid blowing head, the fifth dewaxing liquid blowing head, and the sixth dewaxing liquid blowing head on the front side.

6. The dewaxing liquid sampling and cleaning device for the pathological tissue single-drop dyeing staining system according to claim 1, wherein The Z-axis driving member includes a Z-axis motor mounting plate, a Z-axis motor, a Z-axis nut connecting plate, a Z-axis bearing support plate and a Z-axis bearing. The Z-axis motor mounting plate is connected to the Z-axis motor. The Z-axis nut connecting plate is connected to the Z-axis motor by a nut. The Z-axis bearing support plate is connected to the Z-axis bearing. The Z-axis nut connecting plate is connected to the Z-axis guide rail fixing plate.

7. The dewaxing liquid sampling and cleaning device for the pathological tissue single-droplet staining system according to claim 1, wherein The guide rail assembly includes a Z-axis linear guide rail three and a Z-axis linear guide rail four. The Z-axis linear guide rail three and the Z-axis linear guide rail four are respectively slidably connected to the Z-axis guide rail fixing plate and are respectively installed on the left and right sides of the X-axis guide rail fixing plate.

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