Efficient out-of-focus myopia model based on anti-scraping lens fixing device

Abstract

The utility model provides an efficient out-of-focus myopia model based on an anti-scratch lens fixing device, which comprises a gauze ring, a base, a mounting cylinder and a lens, the inner wall of the lower end of the base is glued with the gauze ring used for shading and dust prevention, and the upper side of the base is movably clamped with the mounting cylinder used for mounting the lens. Compared with the prior art, the laboratory mouse has the advantages that the base is arranged, the through holes in the side edge of the base are matched with the gauze, so that the eyes of the laboratory mouse can be ventilated, the situation that the experiment result is affected by eye discomfort caused by sealing is avoided, and dust and bacteria in the external environment can be intercepted; by matching with sponge columns of which the interiors of spaced through holes are fully sucked with silver ion antibacterial agents, the antibacterial effect can be effectively achieved, infection caused by the influence of bacteria on eye products of laboratory mice is avoided, the stable fixing performance is provided through deformation by arranging a protection plate and a mounting cylinder on the base, and then the lens is fixed more stably.

Description

Technical Field

[0001] The utility model belongs to the technical field of myopia experimental equipment, and particularly relates to an efficient defocus myopia model based on an anti-scratch lens fixing device. Background Technique

[0002] Myopia, as an increasingly serious visual impairment globally, has become an important public health issue, especially among adolescents. According to the statistics of the World Health Organization, it is estimated that by 2050, nearly five billion people in the world will be myopic, and the sharp increase in the number of highly myopic patients has attracted wide attention. The formation mechanism of myopia is complex, including both genetic factors and being closely related to environmental factors. Optical defocus myopia (lens-induced myopia, LIM) is caused by placing a concave lens in front of an animal's eyes or performing laser surgery on the experimental eye, etc., resulting in the object imaging behind the retina, interfering with the normal vision of the animal and causing myopia. Through the regulation of the scleral and choroidal pathways, the morphological changes of the eyeball are controlled, enabling the eyeball to grow compensatorily. When the eye axis grows to coincide with the focus after defocusing, it stops, forming myopia, so as to study the adaptive response of the eye and the pathogenesis of myopia. Research shows that obvious eye axis elongation can be observed in mice wearing concave lenses within a short period, and measurable changes can usually be seen within a week. However, in the process of constructing a defocus myopia model, there are multiple problems, including unstable lens fixation, easy scratching of the lens, inconsistent results due to changes in the experimental environment, inconvenient movement of mice when wearing Elizabethan collars, and reduced food and water intake. In addition, the eyes without defocus lenses are blocked by bedding, resulting in reduced breathability and increased humidity of the eyes, which not only affects the normal physiological functions of the eyes but also may increase the risk of infection. These problems seriously affect the reliability of experimental results. Therefore, there is an urgent need for an efficient and stable defocus myopia model to address these challenges. Therefore, developing a suitable animal model to study the mechanism of myopia, evaluate intervention measures and their effectiveness is an urgent task to be solved. Content of the Utility Model

[0003] Aiming at the deficiencies of the existing technology, the purpose of the utility model is to provide an efficient defocus myopia model based on an anti-scratch lens fixing device to solve the problems raised in the above background technique.

[0004] The utility model is realized through the following technical solutions: An efficient defocus myopia model based on an anti-scratch lens fixing device, including: a gauze ring, a base, a mounting cylinder, and a lens. A gauze ring for shading and dust prevention is adhesively bonded to the inner wall of the lower end of the base. A mounting cylinder for installing the lens is movably clamped on the upper side of the base. A lens for conducting experiments is movably clamped inside the mounting cylinder.

[0005] The base includes a base plate and a protective plate. A protective plate for protecting the lens and the mounting cylinder is adhesively bonded to the rear side of the upper end of the base plate.

[0006] The mounting cylinder includes a cylinder body, a silica gel ring, and a convex rod. A convex rod is provided on the right side of the upper end of the cylinder body, and a silica gel ring for elastic clamping is fixed to the outer wall of the lower end of the cylinder body.

[0007] As a preferred embodiment, a plurality of through holes distributed in a circular structure are radially formed inwardly through the outer wall of the lower end of the base plate. The diameters of the plurality of through holes are 1 mm. Sponge columns filled with silver ion antibacterial agents are filled in the plurality of through holes at intervals. In actual use, the silver ion antibacterial agents contained in the sponge columns can achieve an antibacterial effect, and the inner ends of the sponge columns are not flush with the inner ends of the through holes. The inner ends of the plurality of through holes are all in contact with the outer wall of the gauze ring.

[0008] As a preferred embodiment, a mounting cavity is formed through the upper surface of the base plate. A convex platform is radially formed inwardly at the bottom of the mounting cavity. The inner diameter of the mounting cavity in the upper part of the convex platform is larger than the inner diameter of the mounting cavity in the inner part of the convex platform. A 3M mushroom fastener 1 in a circular structure is adhesively bonded to the lower surface of the base plate. In actual use, a 3M mushroom fastener 2 that is mutually clamped with the 3M mushroom fastener 1 on the lower surface of the base plate is sewn around one eye of the experimental mouse. After the treatment is completed, the 3M mushroom fastener 1 on the lower surface of the base plate and the 3M mushroom fastener 2 sewn on the eye of the experimental mouse can be mutually clamped to fix the base on the experimental mouse.

[0009] As a preferred embodiment, the protective plate is a transparent arc plate, and rounded corners are provided on the left and right sides of the upper end of the protective plate.

[0010] As a preferred embodiment, the height of the silica gel ring matches the depth of the mounting cavity in the upper part of the convex platform, and the silica gel ring is press-fitted with the mounting cavity in the upper part of the convex platform.

[0011] As a preferred embodiment, the lens includes a frame and a concave lens. A concave lens is movably clamped in the middle of the frame. The concave lens is a concave mirror with a power of 25 degrees. The frame is made of a hard rubber material, and the frame is press-fitted with the cylinder body.

[0012] After adopting the above technical solution, the beneficial effects of the present utility model are as follows: By providing a base, the base is snap-connected to the 3M mushroom fastener II on the experimental mouse through the 3M mushroom fastener I, which makes the whole device easy to disassemble and assemble, greatly improving the flexibility of the experiment and allowing for immediate observation of the condition of the experimental mouse's eyes without affecting the continuity of the experiment. The through holes on the side of the base cooperate with the gauze to ventilate the eyes of the experimental mouse, avoiding eye discomfort caused by sealing and affecting the experimental results, and being able to intercept dust and bacteria in the external environment. Cooperating with the sponge column filled with silver ion antibacterial agent in the spaced through holes can effectively carry out antibacterial, avoiding the influence of bacteria on the eyes of the experimental mouse and causing infection;

[0013] The provision of the protective plate and the mounting cylinder on the base can make it difficult for the experimental mouse to touch the worn lens after wearing the lens. The mounting cylinder can be snap-connected to the base through the silicone ring on it and provide stable fixing performance through deformation, thereby making the lens fixed more stably, and the whole device can be quickly disassembled and installed, greatly improving the convenience of the experimental operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0015] Figure 1 It is a schematic diagram of the overall structure of the high-efficiency defocus myopia model based on the anti-scratch lens fixing device of the present utility model.

[0016] Figure 2 It is a schematic diagram of the exploded structure of the high-efficiency defocus myopia model based on the anti-scratch lens fixing device of the present utility model.

[0017] Figure 3 It is a schematic diagram of the base structure of the high-efficiency defocus myopia model based on the anti-scratch lens fixing device of the present utility model.

[0018] In the figure, 100 - gauze ring;

[0019] 200 - base, 210 - base plate, 211 - through hole, 212 - mounting cavity, 213 - boss, 220 - protective plate;

[0020] 300 - mounting cylinder, 310 - silicone ring, 320 - cylinder body, 330 - convex rod;

[0021] 400 - lens, 410 - frame, 420 - concave lens. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0022] The following will clearly and completely describe the technical solutions in the embodiments of the present utility model in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without creative efforts shall fall within the protection scope of the present utility model.

[0023] Please refer to Figures 1 to 3 , the present utility model provides a technical solution: a high-efficiency defocus myopia model based on an anti-scratch lens 400 fixing device, including: a gauze ring 100, a base 200, a mounting cylinder 300, and a lens 400. A gauze ring 100 for shading and dust prevention is adhesively connected to the inner wall of the lower end of the base 200. A mounting cylinder 300 for installing the lens 400 is movably clamped on the upper side of the base 200. A lens 400 for conducting experiments is movably clamped inside the mounting cylinder 300;

[0024] The base 200 includes a base 210 and a protective plate 220. A protective plate 220 for protecting the lens 400 and the mounting cylinder 300 is adhesively connected to the rear side of the upper end of the base 210;

[0025] The mounting cylinder 300 includes a cylinder body 320, a silica gel ring 310, and a convex rod 330. A convex rod 330 is arranged on the right side of the upper end of the cylinder body 320. A silica gel ring 310 for elastic clamping is fixed to the outer wall of the lower end of the cylinder body 320.

[0026] Please refer to Figures 1 to 3 , a plurality of through holes 211 distributed in a circular structure are radially formed inwardly through the outer wall of the lower end of the base 210. The diameters of the plurality of through holes 211 are 1 mm. Sponge columns filled with silver ion antibacterial agents are filled in the plurality of through holes 211 at intervals. In actual use, the silver ion antibacterial agents contained in the sponge columns can achieve an antibacterial effect, and the inner ends of the sponge columns are not flush with the inner ends of the through holes 211. The inner ends of the plurality of through holes 211 are all in contact with the outer wall of the gauze ring 100.

[0027] An installation cavity 212 is formed through the upper surface of the base 210. A convex platform 213 is radially arranged inwardly at the bottom of the installation cavity 212. The inner diameter of the installation cavity 212 in the upper part of the convex platform 213 is larger than the inner diameter of the installation cavity 212 in the convex platform 213. A 3M mushroom fastener one in a circular structure is adhesively connected to the lower surface of the base 210. In actual use, a 3M mushroom fastener two that is mutually clamped with the 3M mushroom fastener one on the lower surface of the base 210 is sewn around one eye of the experimental mouse. After the treatment, clamping the 3M mushroom fastener one on the lower surface of the base 210 with the 3M mushroom fastener two sewn on the eye of the experimental mouse can fix the base 200 on the experimental mouse.

[0028] The protective plate 220 is a transparent arc plate, and rounded corners are provided on the left and right sides of the upper end of the protective plate 220.

[0029] As the first embodiment of the present utility model, in actual use, by providing the base 200, the base 200 is snap-connected to the 3M mushroom fastener two on the experimental mouse through the 3M mushroom fastener one, which makes the whole device easy to disassemble and assemble, greatly improves the flexibility of the experiment and allows immediate viewing of the situation of the experimental mouse's eyes, and does not affect the continuity of the experiment. The through hole 211 on the side of the base 200 cooperates with the gauze to ventilate the eyes of the experimental mouse, avoiding the eye discomfort caused by sealing from affecting the experimental results, and can intercept dust and bacteria in the external environment. Cooperating with the sponge column filled with silver ion antibacterial agent inside the spaced through hole 211 can effectively carry out antibacterial, avoiding the influence of bacteria on the eyes of the experimental mouse and causing infection (the whole device is made of lightweight materials, and the overall weight should be controlled between 15 and 30 grams).

[0030] Please refer to Figures 1 to 2 , the height of the silica gel ring 310 matches the depth of the partial installation cavity 212 on the upper side of the convex platform 213, and the silica gel ring 310 is press-fitted with the partial installation cavity 212 on the upper side of the convex platform 213.

[0031] The lens 400 includes a frame 410 and a concave lens 420. The concave lens 420 is movably clamped in the middle inside the frame 410. The concave lens 420 is a concave mirror with a power of 25 degrees. The frame 410 is made of a hard rubber material, and the frame 410 is press-fitted with the cylinder body 320.

[0032] As the second embodiment of the present utility model, based on the above first embodiment, the setting of the protective plate 220 and the installation cylinder 300 on the base 200 can make it difficult for the experimental mouse to touch the worn lens 400 after wearing the lens 400 (the protective plate 220 near the lower side can prevent the front paws of the experimental mouse from touching the lens 400). The installation cylinder 300 can be snap-connected to the base 200 through the silica gel ring 310 thereon, and provides stable fixing performance through deformation, thereby making the lens 400 more stable, and the whole device can be quickly disassembled and installed, greatly improving the convenience of the experimental operation.

[0033] The above are only the preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included in the protection scope of the present utility model.

Claims

1. An efficient defocus myopia model based on an anti-scratch lens fixing device, comprising: A gauze ring (100), a base (200), a mounting cylinder (300), and a lens (400), characterized in that a gauze ring (100) for shading and dust prevention is adhesively bonded to the inner wall of the lower end of the base (200), a mounting cylinder (300) for mounting the lens (400) is movably clamped on the upper side of the base (200), and a lens (400) for conducting experiments is movably clamped inside the mounting cylinder (300); The base (200) includes a base plate (210) and a protective plate (220), and a protective plate (220) for protecting the lens (400) and the mounting cylinder (300) is adhesively bonded to the rear side of the upper end of the base plate (210); The mounting cylinder (300) includes a cylinder body (320), a silica gel ring (3l0), and a convex rod (330). A convex rod (330) is provided on the right side of the upper end of the cylinder body (320), and a silica gel ring (310) for elastic clamping is fixed to the outer wall of the lower end of the cylinder body (320).

2. The high-efficiency defocus myopia model based on the anti-scratch lens fixing device according to claim 1, characterized in that: A plurality of through holes (211) distributed in an annular structure are radially formed inwardly through the outer wall of the lower end of the base plate (210). The diameters of the plurality of through holes (211) are 1 mm, and sponge columns filled with silver ion antibacterial agents are filled in the plurality of through holes (211) at intervals.

3. The high-efficiency defocus myopia model based on the anti-scratch lens fixing device according to claim 2, wherein: An installation cavity (212) is formed through the upper surface of the base plate (210). A boss (213) is radially formed inwardly at the bottom of the installation cavity (212). The inner diameter of the part of the installation cavity (212) above the boss (213) is larger than the inner diameter of the part of the installation cavity (212) inside the boss (213). A 3M mushroom fastener one in a circular structure is adhesively bonded to the lower surface of the base plate (210).

4. The high-efficiency defocus myopia model based on the anti-scratch lens fixing device according to claim 1, characterized in that: The protective plate (220) is a transparent arc plate, and rounded corners are provided on the left and right sides of the upper end of the protective plate (220).

5. The high-efficiency defocus myopia model based on the anti-scratch lens fixing device according to claim 4, wherein: The height of the silica gel ring (310) matches the depth of the part of the installation cavity (212) above the boss (213), and the silica gel ring (310) is in interference fit with the part of the installation cavity (212) above the boss (213).

6. The high-efficiency defocus myopia model based on the anti-scratch lens fixing device according to claim 1, characterized in that: The lens (400) includes a frame (410) and a concave lens (420). A concave lens (420) is movably clamped in the middle of the frame (410). The concave lens (420) is a concave mirror with a power of 25 degrees. The frame (410) is made of a hard rubber material, and the frame (410) is in interference fit with the cylinder body (320).

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