X-ray targeted positioning guide rail structure for irradiation experiment of laboratory mouse

Abstract

The invention belongs to the technical field of guide rail structures, and discloses an X-ray targeted positioning guide rail structure for a laboratory mouse irradiation experiment, which comprises an equipment base, a positioning guide rail structure rotationally connected between the two limiting upright posts, and an X-ray targeted positioning guide rail structure rotationally connected between the two limiting upright posts, the positioning structure is movably connected to the middle of the positioning guide rail structure, and the positioning structure is used in cooperation with the positioning guide rail structure; the head positioning block is arranged in the middle of the positioning guide rail structure; according to the laboratory mouse positioning and unfolding device, the laboratory mouse positioning and unfolding work is greatly improved, the multiple positioning plates can be adjusted and matched according to use requirements, the laboratory mouse positioning and unfolding device can adapt to laboratory mice of multiple body types, and meanwhile the four limbs and thoracic cavity visceral organs of the laboratory mice can be completely unfolded and dispersed; four limbs of an experimental mouse are respectively fixed on the first clamping arc-shaped piece and the second clamping arc-shaped piece, so that the four limbs of the experimental mouse can be firmly fixed, and the position of the adjusting positioning plate in front of the experimental mouse can be positioned according to use requirements.

Description

Technical Field

[0001] The present invention belongs to the technical field of guide rail structures, and particularly relates to an X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments. Background Art

[0002] An irradiation experiment refers to an experiment in which experimental mice (such as mice, rats, etc.) are used as research objects and are irradiated with ionizing radiation (such as X-rays, γ-rays, proton beams, etc.) to carry out relevant scientific research. Such experiments have important research value in the fields of medicine, biology, radiobiology, etc.

[0003] Observe the damage effects of radiation on the physiological structure, organ function, cells and molecular level of experimental mice, such as whether radiation will cause DNA mutations, apoptosis, tissue inflammation or organ fibrosis. Explore the differences in the effects of different radiation doses, irradiation methods (such as whole-body irradiation, local irradiation), and radiation types on organisms.

[0004] An existing experimental mouse fixing device, referring to an experimental mouse fixer with the application number CN2021231704035, includes: a substrate and at least four fixing seats. The substrate is provided with a working area that can be adsorbed by a magnet. The fixing seat includes a magnetic adsorption seat and a clamping head fixed to the magnetic adsorption seat. The clamping head is used to clamp the limbs of the experimental mouse, and the fixing seat is used for magnetic adsorption and fixation on the working area. The technical solution of the present invention aims to facilitate the injection of experimental mice, and at the same time is convenient to operate and easy to fix experimental mice.

[0005] During irradiation operations, the aggregation of the limb structures and the aggregation of thoracic organs of experimental mice should be reduced, and the positioning and firm fixation of experimental mice should be facilitated.

[0006] When existing experimental mice are undergoing irradiation experiments, due to the lack of a professional positioning structure, the experimental mice are often placed in a customized box during irradiation for positioning and fixing. However, it is difficult to position and place the experimental mice on the equipment because the experimental mice themselves will move around. At the same time, it is necessary to spread out the limb structures and thoracic organs of the experimental mice. Therefore, it is very difficult to place and fix the experimental mice, and the box is already shaped after being made and it is difficult to adapt to experimental mice of various sizes. Once there are too many or too small experimental mice, the box is very difficult to adapt and use; And in some special steps, there will be a situation of irradiating the back of the experimental mouse. In this special step, it is necessary to remove the experimental mouse, flip it and fix it, and then perform the irradiation operation again, which is very difficult to operate, very cumbersome and complex. Therefore, we propose an X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments. Summary of the Invention

[0007] The object of the present invention is to provide an X-ray targeting positioning guide rail structure for experimental mouse irradiation experiments, so as to solve the problems proposed in the above-mentioned background technology.

[0008] To achieve the above object, the present invention provides the following technical solutions: An X-ray targeting positioning guide rail structure for experimental mouse irradiation experiments, including an equipment base, and limiting columns are symmetrically arranged on both sides of the equipment base. It further includes: A positioning guide rail structure, rotatably connected between the two limiting columns; A positioning structure, movably connected to the middle of the positioning guide rail structure, and the positioning structure is used in cooperation with the positioning guide rail structure; A head positioning block, arranged in the middle of the positioning guide rail structure.

[0009] Preferably, a positioning round table is arranged in the middle of the positioning guide rail structure. The positioning round table is connected to the positioning guide rail structure through a plurality of positioning inclined plates, and the plurality of positioning inclined plates are distributed at an angle of forty-five degrees.

[0010] Preferably, the positioning structure includes a plurality of positioning plates. The positioning plates are placed on the top of the positioning guide rail structure. A moving motor is arranged on one side of the top of the positioning plate. A driving limit gear is arranged directly below the moving motor at the bottom of the positioning plate, and the driving limit gear is connected to the moving motor. A driving limit pulley is arranged on one side of the driving limit gear at the bottom of the positioning plate.

[0011] Preferably, an annular slot is opened on the top wall surface of the positioning guide rail structure. A driving inner ring slot is opened inside the annular slot, and the driving inner ring slot is communicated with the annular slot. Driving teeth are arranged on the arc-shaped inner wall of the driving inner ring slot, and the driving teeth are meshed with the driving limit gear. The driving limit pulley is in contact with the inner wall of the positioning guide rail structure.

[0012] Preferably, a plurality of first clamping arc-shaped members and second clamping arc-shaped members are arranged on the top of the positioning plate, and the two are arranged in parallel in the opposite direction. A protective rubber layer is arranged on the inner wall of each first clamping arc-shaped member and second clamping arc-shaped member. A limit switch plate is arranged in the middle of the plurality of first clamping arc-shaped members and second clamping arc-shaped members; Arc-shaped member rotating shafts are respectively arranged on both sides inside the positioning plate. The arc-shaped member rotating shafts are respectively connected to the first clamping arc-shaped member and the second clamping arc-shaped member through connecting blocks. A height adjustment gear is arranged at the end of the connecting block. U-shaped seats are arranged at positions close to the arc-shaped member rotating shafts on both sides inside the positioning plate. A height adjustment rod is arranged at the bottom of the U-shaped seat. A height adjustment tooth is arranged on one side of the U-shaped seat, and the height adjustment tooth is meshed with the height adjustment gear. An anti-offset inner column is arranged on the other side of the U-shaped seat. An anti-offset sleeve is arranged at a position close to the anti-offset inner column inside the positioning plate, and the anti-offset sleeve and the anti-offset inner column are used in cooperation with each other.

[0013] Preferably, when the limit switch board is pressed, the limit switch board will send an operation instruction to the height adjustment rod. When the limit switch board is pressed for the first time, the height adjustment rod will contract, causing the height adjustment rod to drive the U-shaped seat and the height adjustment teeth to move downward. At this time, the height adjustment teeth are engaged with the height adjustment gear, causing the height adjustment gear and the arc-shaped member rotating shaft to rotate, thereby causing the connecting block and the second clamping arc-shaped member to rotate. When the limit switch board is pressed for the second time, the height adjustment rod will stop operating, and at this time, it plays a fixing role for the U-shaped seat, the height adjustment teeth, and the arc-shaped member rotating shaft. When the limit switch board is pressed for the third time, the height adjustment rod will automatically reset, causing the U-shaped seat, the height adjustment teeth, the height adjustment gear, and the arc-shaped member rotating shaft to return to their original positions.

[0014] Preferably, limiting rotating shafts are provided on one side of the limiting columns close to the positioning guide rail structure, and the positioning guide rail structure is rotationally connected to the limiting columns through two limiting rotating shafts.

[0015] Preferably, a support column is rotationally connected to one side of the limiting column, and a support gasket is provided at the top of the support column. When the positioning guide rail structure is in a parallel state with the equipment base, the top wall of the support gasket is in contact with the bottom wall of the positioning guide rail structure; The support column is rotationally connected to the limiting column through a support rotating shaft, and a placement groove for cooperating with the support column is provided on the surface of the limiting column.

[0016] Preferably, a placement housing is provided on one side of the limiting column, a limiting motor is provided inside the placement housing, and the end of the output shaft of the limiting motor is connected to the support rotating shaft through a limiting toothed belt. When the limiting motor operates, it drives the limiting toothed belt and the support rotating shaft to rotate together.

[0017] Preferably, an elongated connecting piece is provided between two positioning plates on the same straight line, and the positioning round table and the top walls of the multiple positioning plates are all in the same plane.

[0018] Compared with the prior art, the beneficial effects of the present invention are: The present invention greatly improves the positioning and unfolding operations of experimental mice. Multiple positioning plates can be adjusted and adapted according to the usage requirements. It can not only adapt to experimental mice of multiple body sizes, but also completely unfold and disperse the limbs and thoracic organs of the experimental mice. The limbs of the experimental mice are respectively fixed on the first clamping arc-shaped member and the second clamping arc-shaped member, and the limbs of the experimental mice can be firmly fixed. And according to the usage requirements, the position of the positioning plate can be adjusted before positioning the experimental mouse, or the position of the positioning plate can be adjusted after positioning the experimental mouse. It is very flexible and convenient to use and can be used in cooperation with experimental requirements.

[0019] When positioning the limbs of the experimental mouse through the positioning plate, it is also very convenient. When the limbs of the experimental mouse are located at the positions of the first clamping arc-shaped member and the second clamping arc-shaped member, the limbs will contact the second clamping arc-shaped member. Gently pressing down can make the height adjustment rod operate and contract, so that the first clamping arc-shaped member and the second clamping arc-shaped member rotate around the arc-shaped member rotating shaft, and the first clamping arc-shaped member and the second clamping arc-shaped member will squeeze and restrain the limbs, that is, the experimental mouse is positioned and fixed. The operation is very convenient, and it is used quickly, and the positioning efficiency of the experimental mouse is relatively fast.

[0020] At the same time, after positioning the experimental mouse on the device, the positioning guide rail structure can be flipped according to the use requirements. After the irradiation of the experimental mouse surface is completed, rotating the positioning guide rail structure through the limiting rotating shaft can display the back of the experimental mouse above. At this time, the irradiation operation can be carried out on the back of the experimental mouse, reducing the situation of repeatedly positioning and removing it, reducing the burden on the experimental mouse, and improving the operation efficiency.

[0021] The positioning plate moves through the driving limit gear and the driving limit pulley. After operating the moving motor, the moving motor drives the driving limit gear to rotate together. The driving limit gear is meshed with the driving tooth teeth, which drives the positioning plate to move. The two horizontal positioning plates are connected by a lengthening connecting piece, and they can move to make the experimental mouse always in the exact middle of the device after positioning the experimental mouse, and the auxiliary operation effect is better. Brief Description of the Drawings

[0022] Figure 1 is the structural schematic diagram of the present invention; Figure 2 is the three-dimensional view of the support column of the present invention; Figure 3 is the schematic diagram after the rotation of the positioning guide rail structure of the present invention; Figure 4 is the side view of the limiting column of the present invention; Figure 5 is the top view of the positioning guide rail structure of the present invention; Figure 6 is the exploded view of the positioning plate of the present invention; Figure 7 is the exploded view of the positioning plate from the top view angle of the present invention; Figure 8 is the three-dimensional view of the second clamping arc-shaped member of the present invention; Figure 9 is the main view cross-sectional view of the second clamping arc-shaped member of the present invention; Figure 10 of the present invention Figure 9 enlarged view at A in; Figure 11 is the top view of the annular slot of the present invention; Figure 12 is the bottom perspective view of the positioning guide rail structure of the present invention; Figure 13 is the perspective view of the positioning plate of the present invention; Figure 14 is the sectional perspective view of the positioning guide rail structure of the present invention; Figure 15 is the bottom perspective view of the positioning guide rail structure of the present invention; In the figure: 100, equipment base; 101, limiting column; 102, limiting rotating shaft; 103, placement housing; 104, supporting rotating shaft; 105, placement groove; 106, supporting column; 107, supporting gasket; 108, limiting toothed belt; 109, limiting motor; 200, positioning guide rail structure; 201, annular slot; 202, driving inner ring groove; 203, driving tooth; 300, positioning structure; 301, positioning plate; 302, moving motor; 303, first clamping arc; 304, driving limit pulley; 305, driving limit gear; 306, second clamping arc; 307, limit switch plate; 308, arc rotating shaft; 309, connecting block; 310, protective rubber layer; 311, anti-offset sleeve; 312, anti-offset inner column; 313, U-shaped seat; 314, height adjusting rod; 315, height adjusting tooth; 316, height adjusting gear; 317, lengthening connecting piece; 400, head positioning block; 500, positioning frustum; 501, positioning inclined plate. Specific embodiments

[0023] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments in the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work fall within the protection scope of the present invention.

[0024] Please refer to Figures 1 to 15 , the present invention provides a technical solution: an X-ray targeting positioning guide rail structure for experimental mouse irradiation experiments, including an equipment base 100, and limiting columns 101 are symmetrically arranged on both sides of the equipment base 100. It further includes: A positioning guide rail structure 200, rotatably connected between the two limiting columns 101; A positioning structure 300, movably connected to the middle of the positioning guide rail structure 200, and the positioning structure 300 is used in cooperation with the positioning guide rail structure 200; The head positioning block 400 is arranged in the middle of the positioning guide rail structure 200.

[0025] The present invention greatly improves the positioning and unfolding operations of experimental mice. Multiple positioning plates 301 can be adjusted and adapted according to the usage requirements. It can not only adapt to experimental mice of multiple body sizes, but also completely unfold and disperse the limbs and thoracic organs of the experimental mice. The limbs of the experimental mice are respectively fixed on the first clamping arc-shaped member 303 and the second clamping arc-shaped member 306, and the limbs of the experimental mice can be firmly fixed. According to the usage requirements, the position of the positioning plate 301 can be adjusted before positioning the experimental mouse, or the position of the positioning plate 301 can be adjusted after positioning the experimental mouse. It is very flexible and convenient to use and can be used in cooperation with experimental requirements.

[0026] In this embodiment, preferably, as Figure 1 , Figure 2 , Figure 3 , Figure 5 , a positioning round table 500 is arranged in the middle of the positioning guide rail structure 200. The positioning round table 500 is connected to the positioning guide rail structure 200 through a plurality of positioning inclined plates 501, and the plurality of positioning inclined plates 501 are distributed at an angle of forty-five degrees.

[0027] The positioning round table 500 can support the experimental mouse after the experimental mouse is positioned on the device, making the experimental mouse more comfortable. At the same time, when the experimental mouse needs dorsal irradiation, after the device is flipped 180 degrees, the positioning round table 500 will not block most of the area of the experimental mouse, eliminating the need to loosen and reposition the experimental mouse, improving the operation efficiency and reducing cumbersome steps.

[0028] In this embodiment, preferably, as Figure 1 , Figure 2 , Figure 3 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , the positioning structure 300 includes a plurality of positioning plates 301. The positioning plates 301 are placed on the top of the positioning guide rail structure 200. A moving motor 302 is arranged on one side of the top of the positioning plate 301. A driving limit gear 305 is arranged directly below the moving motor 302 at the bottom of the positioning plate 301, and the driving limit gear 305 is connected to the moving motor 302. A driving limit pulley 304 is arranged on one side of the driving limit gear 305 at the bottom of the positioning plate 301.

[0029] Two positioning plates 301 on the same straight line can move simultaneously and always remain on the same straight line during the movement.

[0030] When the moving motor 302 operates, the output shaft of the moving motor 302 drives the driving limit gear 305 to rotate together.

[0031] In this embodiment, preferably, as Figure 1 , Figure 2 , Figure 3 , Figure 12 , Figure 13 , Figure 14 , Figure 15 , on the top wall surface of the positioning guide rail structure 200, an annular slot 201 is provided. Inside the annular slot 201, a driving inner ring slot 202 is provided, and the driving inner ring slot 202 communicates with the annular slot 201. On the arc-shaped inner wall of the driving inner ring slot 202, driving teeth 203 are provided, and the driving teeth 203 are meshed and connected with the driving limit gear 305. The driving limit pulley 304 is in contact with the inner wall of the positioning guide rail structure 200.

[0032] When the positioning plate 301 needs to move, operate the moving motor 302. The output shaft of the moving motor 302 drives the driving limit gear 305 to rotate together. The continuous meshing of the driving limit gear 305 and the driving teeth 203 enables the driving limit gear 305 to drive the positioning plate 301 to move. The driving limit pulley 304 located at the bottom of the positioning plate 301 will move along the inner wall of the positioning guide rail structure 200, playing a limiting role.

[0033] In this embodiment, preferably, as Figure 1 , Figure 2 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Figure 9 , Figure 10 , on the top of the positioning plate 301, a plurality of first clamping arc-shaped members 303 and second clamping arc-shaped members 306 are provided, and the two are arranged in reverse parallel. On the inner walls of each first clamping arc-shaped member 303 and second clamping arc-shaped member 306, a protective rubber layer 310 is provided. In the middle of the plurality of first clamping arc-shaped members 303 and second clamping arc-shaped members 306, a limit switch plate 307 is provided; On both sides inside the positioning plate 301, arc-shaped member rotating shafts 308 are respectively provided. The arc-shaped member rotating shafts 308 are respectively connected to the first clamping arc-shaped members 303 and second clamping arc-shaped members 306 through connection blocks 309. At the end of the connection block 309, a height adjustment gear 316 is provided. At positions close to the arc-shaped member rotating shafts 308 on both sides inside the positioning plate 301, U-shaped seats 313 are provided. At the bottom of the U-shaped seat 313, a height adjustment rod 314 is provided. On one side of the U-shaped seat 313, height adjustment teeth 315 are provided, and the height adjustment teeth 315 are meshed and connected with the height adjustment gear 316. On the other side of the U-shaped seat 313, an anti-offset inner column 312 is provided. At a position inside the positioning plate 301 close to the anti-offset inner column 312, an anti-offset sleeve 311 is provided, and the anti-offset sleeve 311 and the anti-offset inner column 312 are used in cooperation with each other.

[0034] When positioning the limbs of the experimental mouse through the positioning plate 301, it is also very convenient. When the limbs of the experimental mouse are located at the positions of the first clamping arc-shaped member 303 and the second clamping arc-shaped member 306, the limbs will contact the second clamping arc-shaped member 306. Gently pressing down can make the height adjustment rod 314 operate and contract, so that the first clamping arc-shaped member 303 and the second clamping arc-shaped member 306 rotate around the arc-shaped member rotating shaft 308, so that the first clamping arc-shaped member 303 and the second clamping arc-shaped member 306 squeeze and restrain the limbs, that is, the experimental mouse is positioned and fixed. The operation is very convenient, and it is used quickly, and the positioning efficiency of the experimental mouse is relatively fast.

[0035] The positioning plate 301 moves through the driving limit gear 305 and the driving limit pulley 304. After operating the moving motor 302, the moving motor 302 drives the driving limit gear 305 to rotate together. The driving limit gear 305 is meshed and connected with the driving tooth 203, which drives the positioning plate 301 to move. The two horizontal positioning plates 301 are connected by a lengthening connecting piece 317. The two can move, so that after the positioning plate 301 positions the experimental mouse, the experimental mouse can always be in the center of the equipment, and the auxiliary operation effect is better.

[0036] In this embodiment, preferably, as Figure 1 , Figure 2 , Figure 5 , Figure 6 , Figure 7 , Figure 8 , Figure 9 , Figure 10 , when the limit switch plate 307 is pressed, the limit switch plate 307 will send an operation instruction to the height adjustment rod 314. When the limit switch plate 307 is pressed for the first time, the height adjustment rod 314 will contract, so that the height adjustment rod 314 drives the U-shaped seat 313 and the height adjustment tooth 315 to move downward. At this time, the height adjustment tooth 315 is meshed and connected with the height adjustment gear 316, so that the height adjustment gear 316 and the arc-shaped member rotating shaft 308 rotate, so that the connecting block 309 and the second clamping arc-shaped member 306 rotate; when the limit switch plate 307 is pressed for the second time, the height adjustment rod 314 will stop operating, and at this time, the U-shaped seat 313, the height adjustment tooth 315, and the arc-shaped member rotating shaft 308 are fixed; when the limit switch plate 307 is pressed for the third time, the height adjustment rod 314 will automatically reset, so that the U-shaped seat 313, the height adjustment tooth 315, the height adjustment gear 316, and the arc-shaped member rotating shaft 308 return to their original positions.

[0037] It is relatively simple to position the first clamping arc-shaped member 303 and the limit switch plate 307, and only need to press the limit switch plate 307.

[0038] In this embodiment, preferably, asFigure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , it is defined that limiting rotating shafts 102 are provided on one side of the limiting columns 101 close to the positioning guide rail structure 200, and the positioning guide rail structure 200 is rotationally connected to the limiting columns 101 through two limiting rotating shafts 102.

[0039] After positioning the experimental rats on the device, the positioning guide rail structure 200 can be flipped according to the usage requirements. After the surface irradiation of the experimental rats is completed, the positioning guide rail structure 200 is rotated through the limiting rotating shaft 102, and then the back of the experimental rats can be presented upward. At this time, the irradiation operation can be carried out on the back of the experimental rats, reducing the situation of repeatedly positioning and removing them, reducing the burden on the experimental rats, and improving the operation efficiency.

[0040] In this embodiment, preferably, as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 , a support column 106 is rotationally connected to one side of the limiting column 101, and a support gasket 107 is provided at the top of the support column 106. When the positioning guide rail structure 200 is in a parallel state with the device base 100, the top wall of the support gasket 107 is in contact with the bottom wall of the positioning guide rail structure 200; The support column 106 is rotationally connected to the limiting column 101 through a support rotating shaft 104, and a placement groove 105 for cooperating with the support column 106 is formed on the surface of the limiting column 101.

[0041] The two support gaskets 107 can support the positioning guide rail structure 200, making the positioning guide rail structure 200 very stable when it is in a parallel state with the device base 100.

[0042] Before the positioning guide rail structure 200 rotates, the support column 106 and the support gasket 107 rotate through the support rotating shaft 104, so that a part of the support column 106 is received in the placement groove 105. After the support column 106 and the support gasket 107 are in the received state, when the positioning guide rail structure 200 rotates around the limiting rotating shaft 102 as the center, the positioning guide rail structure 200 will not contact the support column 106.

[0043] In this embodiment, preferably, as Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5, on one side of the limiting column 101, there is a placement housing 103. Inside the placement housing 103, there is a limiting motor 109. And the end of the output shaft of the limiting motor 109 is connected to the support rotating shaft 104 through a limiting toothed belt 108. When the limiting motor 109 operates, it drives the limiting toothed belt 108 and the support rotating shaft 104 to rotate together.

[0044] In this embodiment, preferably, as Figure 1 , Figure 5 , Figure 7 , between two positioning plates 301 on the same straight line, there is an extended connecting piece 317, and the positioning frustum 500 and the top walls of multiple positioning plates 301 are all in the same plane.

[0045] After the experimental mouse is placed on the device, the back position of the experimental mouse will be placed on the positioning frustum 500, the head is located at the position of the head positioning block 400, and the four limbs are located on the positioning plates 301. And the positioning frustum 500, the head positioning block 400, and the positioning plates 301 are all in the same plane, which not only makes the irradiation test more accurate, but also makes the experimental mouse itself more relaxed.

[0046] Working principle and usage process: Position the experimental mouse on the positioning guide rail structure 200, align the head of the experimental mouse with the position of the head positioning block 400, and then slowly press the limit switch plate 307, so that the limit switch plate 307 sends an instruction to the height adjustment rod 314. The height adjustment rod 314 will contract, causing the height adjustment rod 314 to drive the U-shaped seat 313 and the height adjustment teeth 315 to move downward. At this time, the height adjustment teeth 315 are engaged with the height adjustment gear 316, causing the height adjustment gear 316 and the arc-shaped part rotating shaft 308 to rotate, thereby causing the connecting block 309 and the second clamping arc-shaped part 306 to rotate, that is, causing the second clamping arc-shaped part 306 and the first clamping arc-shaped part 303 to position the neck position of the experimental mouse; At the same time, the four limbs of the experimental mouse are similarly fixed on multiple positioning plates 301. Press the limit switch plate 307, so that the four limbs of the experimental mouse are all fixed on the positioning plates 301 through the first clamping arc-shaped part 303 and the second clamping arc-shaped part 306. At this time, the moving motor 302 can be operated, and the moving motor 302 drives the driving limit gear 305 to rotate together. The driving limit gear 305 is engaged with the driving teeth 203, that is, drives the positioning plate 301 to move. And the two horizontal positioning plates 301 are connected by an extended connecting piece 317. The two can move, so that after the positioning plate 301 positions the experimental mouse, the experimental mouse can always be in the center of the device, and the auxiliary operation effect is better. It can not only adapt to experimental mice of multiple body types, but also completely spread and disperse the four limbs and thoracic organs of the experimental mouse; When the surface irradiation operation of the experimental mouse is completed and further irradiation of the back is required, the positioning guide rail structure 200 can be flipped according to the usage requirements. After the surface irradiation of the experimental mouse is completed, rotate the positioning guide rail structure 200 through the defined rotating shaft 102, and the back of the experimental mouse can be shown above. Then, limit the operation of the motor 109, which will drive the defined toothed belt 108 and the support rotating shaft 104 to rotate together, so that the defined toothed belt 108 and the support gasket 107 rotate to the bottom wall of the positioning guide rail structure 200, and the support gasket 107 supports the positioning guide rail structure 200, making the whole positioning guide rail structure 200 more stable. At this time, the irradiation operation can be carried out on the back of the experimental mouse, reducing the situation of repeatedly positioning and removing it, reducing the burden on the experimental mouse, and improving the operation efficiency.

[0047] The above is only used to illustrate the technical solution of the present invention and not to limit it. Any other modifications or equivalent replacements made by those of ordinary skill in the art to the technical solution of the present invention shall be covered by the scope of the claims of the present invention as long as they do not depart from the spirit and scope of the technical solution of the present invention.

Claims

1. X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiment, including an equipment base, and limiting columns are symmetrically arranged on both sides of the equipment base, and it is characterized in that: Further included are: A positioning guide rail structure, rotatably connected between two limiting columns; A positioning structure, movably connected to the middle of the positioning guide rail structure, and the positioning structure is used in cooperation with the positioning guide rail structure; A head positioning block, arranged in the middle of the positioning guide rail structure.

2. The X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments according to claim 1, characterized in that: A positioning round platform is arranged in the middle of the positioning guide rail structure. The positioning round platform is connected to the positioning guide rail structure through a plurality of positioning inclined plates, and the plurality of positioning inclined plates are distributed at an angle of forty-five degrees.

3. The X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments according to claim 1 or 2, characterized in that: The positioning structure includes a plurality of positioning plates. The positioning plates are placed on the top of the positioning guide rail structure. A moving motor is arranged on one side of the top of the positioning plate. A driving limit gear is arranged directly below the moving motor at the bottom of the positioning plate, and the driving limit gear is connected to the moving motor. A driving limit pulley is arranged on one side of the driving limit gear at the bottom of the positioning plate.

4. The X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments according to claim 3, characterized in that: An annular groove is formed on the top wall surface of the positioning guide rail structure. A driving inner ring groove is formed inside the annular groove, and the driving inner ring groove is communicated with the annular groove. Driving teeth are arranged on the arc-shaped inner wall of the driving inner ring groove, and the driving teeth are meshed and connected with the driving limit gear. The driving limit pulley is in contact with the inner wall of the positioning guide rail structure.

5. The X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments according to claim 3, characterized in that: A plurality of first clamping arc-shaped members and second clamping arc-shaped members are arranged on the top of the positioning plate, and the two are arranged in parallel in the opposite direction. A protective rubber layer is arranged on the inner wall of each first clamping arc-shaped member and second clamping arc-shaped member. A limit switch plate is arranged in the middle of the plurality of first clamping arc-shaped members and second clamping arc-shaped members; Arc-shaped member rotating shafts are respectively arranged on both sides inside the positioning plate. The arc-shaped member rotating shafts are respectively connected to the first clamping arc-shaped member and the second clamping arc-shaped member through connecting blocks. A height adjustment gear is arranged at the end of the connecting block. U-shaped seats are arranged at positions close to the arc-shaped member rotating shafts on both sides inside the positioning plate. A height adjustment rod is arranged at the bottom of the U-shaped seat. A height adjustment tooth is arranged on one side of the U-shaped seat, and the height adjustment tooth is meshed and connected with the height adjustment gear. An anti-offset inner column is arranged on the other side of the U-shaped seat. An anti-offset sleeve is arranged at a position close to the anti-offset inner column inside the positioning plate, and the anti-offset sleeve is used in cooperation with the anti-offset inner column.

6. The X-ray targeting and positioning guide rail structure for mouse irradiation experiments according to claim 5, characterized in that: When the limit switch plate is pressed, the limit switch plate will send an operation instruction to the height adjustment rod. When the limit switch plate is pressed for the first time, the height adjustment rod will contract, so that the height adjustment rod drives the U-shaped seat and the height adjustment tooth to move downward. At this time, the height adjustment tooth is meshed and connected with the height adjustment gear, so that the height adjustment gear and the arc-shaped member rotating shaft rotate, thereby making the connecting block and the second clamping arc-shaped member rotate; when the limit switch plate is pressed for the second time, the height adjustment rod will stop operating, and at this time, the U-shaped seat, the height adjustment tooth and the arc-shaped member rotating shaft are fixed; when the limit switch plate is pressed for the third time, the height adjustment rod will automatically reset, so that the U-shaped seat, the height adjustment tooth, the height adjustment gear and the arc-shaped member rotating shaft return to their original positions.

7. The X-ray target positioning guide rail structure for experimental mouse irradiation experiments according to claim 1, characterized in that: Limiting rotating shafts are arranged on one side of each of the limiting columns close to the positioning guide rail structure, and the positioning guide rail structure is rotatably connected to the limiting columns through the two limiting rotating shafts.

8. The X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments according to claim 7, characterized in that: One side of the limiting column is rotatably connected with a supporting column, and a supporting gasket is arranged at the top of the supporting column. When the positioning guide rail structure is in a parallel state with the equipment base, the top wall of the supporting gasket is in contact with the bottom wall of the positioning guide rail structure. The supporting column is rotatably connected with the limiting column through a supporting rotating shaft, and a placing groove for cooperating with the supporting column is formed on the surface of the limiting column.

9. The X-ray target positioning guide rail structure for experimental mouse irradiation experiments according to claim 8, characterized in that: A placing shell is arranged on one side of the limiting column, a limiting motor is arranged inside the placing shell, and the end of the output shaft of the limiting motor is connected with the supporting rotating shaft through a limiting toothed belt. When the limiting motor operates, the limiting toothed belt and the supporting rotating shaft are driven to rotate together.

10. The X-ray targeting and positioning guide rail structure for experimental mouse irradiation experiments according to claim 2, characterized in that: An extension connecting piece is arranged between two positioning plates on the same straight line, and the positioning round table and the top walls of the multiple positioning plates are all in the same plane.

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