Liquid medicine test stirring device for biopharmacy

Abstract

The utility model discloses a liquid medicine test stirring device for biological pharmacy, and relates to the technical field of pharmaceutical stirring equipment. The liquid medicine test stirring device for biopharmacy comprises a shell assembly, a stirring assembly and an air injection assembly. The shell assembly comprises a mixing barrel, a liquid inlet pipe and a liquid outlet pipe. The liquid inlet pipe is communicated with the upper end of the mixing barrel. And the liquid outlet pipe is communicated with the inner bottom of the mixing barrel. The stirring assembly is installed on the mixing barrel, and the stirring end of the stirring assembly is located in the mixing barrel. The air injection assembly is arranged at the inner bottom of the mixing barrel and is positioned below the stirring assembly. And the air injection assembly is configured to blow air to the inner bottom of the mixing barrel. When the device is used for stirring in a liquid medicine test, the air injection assembly can spray settled medicine particle powder, so that the medicine particle powder moves upwards and is fully dissolved or dispersed, the bottom settling amount is reduced, and the difficulty of cleaning the mixing barrel after stirring is finished is reduced.

Description

Technical Field

[0001] The present application relates to the technical field of pharmaceutical stirring equipment, and in particular to a stirring device for a biopharmaceutical drug liquid test. Background Art

[0002] When preparing medicine, it is necessary to mix the medicine liquid, and the effect of mixing directly affects the effect of medicine preparation.

[0003] The Chinese invention patent application with publication number CN111729553A discloses a pharmaceutical liquid test stirring device, which includes a support plate, the top of which is fixedly connected to a processing box, the left inner wall of the processing box is provided with a placement groove, the left inner wall of the placement groove is fixedly connected to a plurality of fixing rings, the inner surface of the fixing ring is fixedly connected to a heating rod, the top ends of the processing box are provided with connection grooves, the inner surface of the connection groove is detachably fixedly connected to a connection block, the top of the connection block is fixedly connected to a cover plate, and the top of the cover plate is fixedly connected to a handle. The pharmaceutical liquid test stirring device, through the structure of the processing box, connection groove, connection block, cover plate and handle, is convenient for adding materials to the interior of the processing box, and is also convenient for cleaning and replacing the internal devices of the processing box. The liquid in the processing box can be discharged from the liquid outlet pipe through the structure of the liquid outlet pipe and the sealing cap.

[0004] When using the aforementioned liquid medicine stirring device to mix liquid medicine, undissolved particles and powders in the liquid tend to sink to the bottom. After stirring, to prevent interference with the next mixing, the stirring device must be manually cleaned. This is typically done by manually pouring water and using a long brush to clean the inside of the device. However, since much of the liquid medicine sinks to the bottom, cleaning is laborious. Utility Model Content

[0005] In view of the problem that when using the liquid medicine test stirring device of the related technology to mix the liquid medicine, the granular powder materials that have not dissolved in the liquid medicine tend to sink to the bottom, and manual cleaning of the sediment materials is relatively laborious, this application proposes the following improvement plan.

[0006] A biopharmaceutical liquid test stirring device comprises a shell component, a stirring component and an air jet component.

[0007] The housing assembly includes a mixing barrel, a liquid inlet pipe, and a liquid outlet pipe. The liquid inlet pipe is connected to the upper end of the mixing barrel. The liquid outlet pipe is connected to the inner bottom of the mixing barrel.

[0008] The stirring component is installed on the mixing barrel, and the stirring end of the stirring component is located in the mixing barrel.

[0009] The air jet assembly is arranged at the inner bottom of the mixing barrel and is located below the stirring assembly. The air jet assembly is configured to blow air toward the inner bottom of the mixing barrel.

[0010] By adopting the above technical solution, when the device is used for stirring a liquid medicine test, the jet assembly can spray up the settled drug particle powder, so that the drug particle powder moves upward, fully dissolves or disperses, reduces the amount of sedimentation, and reduces the difficulty of cleaning the mixing barrel after stirring.

[0011] A preferred structure of the biopharmaceutical liquid test stirring device is that the housing assembly further includes a heating base, which is arranged on the outer bottom of the mixing barrel.

[0012] By adopting the above technical solution, the heating base can heat the liquid medicine in the mixing barrel.

[0013] A preferred structure of the biopharmaceutical liquid testing stirring device is that the air jet assembly includes an air pump and a hollow disc cartridge. The hollow disc cartridge is disposed at the inner bottom of the mixing barrel. The air pump is disposed outside the mixing barrel, and its air supply pipe further passes through the mixing barrel and connects to the hollow disc cartridge. The upper surface of the hollow disc cartridge has multiple air holes. The gas output by the air pump is directed into these air holes.

[0014] By adopting the above technical solution, the air pump generates gas and ventilates the bottom of the mixing barrel through the air holes to blow up the sediment.

[0015] A preferred structure of the biopharmaceutical liquid test stirring device is that the hollow disc box has a plurality of air-blowing columns located in the inner circle and a plurality of air-blowing columns located in the outer circle, and each air-blowing column has one of the air holes.

[0016] By adopting the above technical solution, the double-circle air holes cover a large area and the air outlet is uniform, and the efficiency of blowing up the sediment is high.

[0017] A preferred structure of the biopharmaceutical liquid testing stirring device is that the air injection assembly further includes an inner ring protective ring and an outer ring protective ring. The inner ring protective ring is sleeved over the multiple air-blowing columns of the inner ring, each air-blowing column extending upward through the inner ring protective ring. The outer ring protective ring is sleeved over the multiple air-blowing columns of the outer ring, each air-blowing column extending upward through the outer ring protective ring.

[0018] By adopting the above technical solution, the inner ring protection ring and the outer ring protection ring can protect the air blowing column and reduce the probability of damage to the air blowing column.

[0019] A preferred structure of the biopharmaceutical liquid testing stirring device is that the air injection assembly further includes a cover plate. The cover plate covers the inner and outer protective rings. The cover plate defines multiple through-holes in the inner ring and multiple through-holes in the outer ring. The multiple air injection columns in the inner ring are connected to the multiple through-holes in the inner ring. The multiple air injection columns in the outer ring are connected to the multiple through-holes in the outer ring.

[0020] By adopting the above technical solution, the cover plate can cover most of the body of the air column and the inner ring protection ring and the outer ring protection ring. The sediment can fall on the cover plate and is not easy to settle on the sides of the inner ring protection ring and the outer ring protection ring, thereby reducing the accumulation of sediment and improving the efficiency of blowing up the sediment.

[0021] A preferred structure of the biopharmaceutical liquid testing stirring device is as follows: the stirring assembly includes a motor, a rotating shaft, and a plurality of stirring blades. The motor is mounted above the mixing barrel, connected to the rotating shaft, and the rotating shaft penetrates the mixing barrel without contact. The plurality of stirring blades are fixed to the rotating shaft. The plurality of stirring blades are located within the mixing barrel. The rotating shaft and the plurality of stirring blades are both located above the cover plate.

[0022] By adopting the above technical solution, the stirring component can stir the liquid medicine efficiently.

[0023] A preferred structure of the biopharmaceutical liquid testing stirring device includes a cleaning assembly. The cleaning assembly includes a water ring and a water rack. The water ring is mounted above the mixing barrel, and the water rack is disposed within the mixing barrel. The water ring is connected to the water rack. The water ring has a water inlet. Each of the water racks has multiple spray heads, which are arranged around the stirring assembly.

[0024] By adopting the above technical solution, the water inlet is connected to a high-pressure water source, and water is sprayed toward the stirring assembly from multiple spray heads. Since the spray heads can spray water mist over a large area, the water can also be sprayed toward the inner wall of the mixing barrel, thereby fully covering the stirring assembly and the inner wall of the mixing barrel, so that they are fully cleaned, reducing the intensity of subsequent manual cleaning, and even eliminating the need for manual cleaning.

[0025] In summary, the biopharmaceutical liquid test stirring device of the present application has the following beneficial effects: when used for liquid test stirring, the jet assembly can spray settled drug particles and powder, causing them to move upward, fully dissolving or dispersing them, reducing the amount of sediment, and making it easier to clean the mixing barrel after stirring. The cleaning assembly can spray water mist onto the stirring assembly and the inner wall of the mixing barrel to thoroughly clean them, reducing the intensity of subsequent manual cleaning and even eliminating the need for manual cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 This is a structural diagram of a stirring device for biopharmaceutical liquid testing, in which the mixing barrel is cut into sections to show the internal structure.

[0027] Figure 2 for Figure 1 Structural diagram of the housing assembly.

[0028] Figure 3 for Figure 1 Partial structural diagram of the jet assembly.

[0029] Figure 4 for Figure 1 The complete structural diagram of the jet assembly.

[0030] Figure 5 for Figure 1 Structural diagram of the stirring component.

[0031] Figure 6 for Figure 1 Structural diagram of the cleaning components.

[0032] Figure 7 for Figure 1 Another labeled diagram of .

[0033] Figure numerals: 1. Shell assembly; 2. Stirring assembly; 3. Jet assembly; 11. Mixing barrel; 12. Liquid inlet pipe; 13. Liquid outlet pipe; 14. Heating base; 31. Air pump; 32. Hollow disc box; 3211. Air hole; 321. Air column; 33. Inner ring protection ring; 34. Outer ring protection ring; 35. Cover plate; 351. Through hole; 21. Motor; 22. Rotating shaft; 23. Stirring blade; 4. Cleaning assembly; 41. Water ring; 42. Water rack; 411. Water inlet; 421. Water box; 412. Conduit; 422. Spray head. DETAILED DESCRIPTION

[0034] The following will be combined with the accompanying drawings to clearly and completely describe the technical solutions in the embodiments. Obviously, the embodiments described are only some embodiments of the present invention, not all embodiments. Based on the following embodiments, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0035] like Figure 1 A biopharmaceutical liquid test stirring device includes a shell component 1, a stirring component 2 and an air jet component 3.

[0036] like Figure 2The housing assembly 1 includes a mixing barrel 11, a liquid inlet pipe 12, and a liquid outlet pipe 13. The liquid inlet pipe 12 is connected to the upper end of the mixing barrel 11. The liquid outlet pipe 13 is connected to the inner bottom of the mixing barrel 11. Both the liquid inlet pipe 12 and the liquid outlet pipe 13 may be equipped with valves. The liquid medicine can be poured into the mixing barrel 11 through the liquid inlet pipe 12. After stirring, the liquid medicine can be discharged through the liquid outlet pipe 13.

[0037] The stirring component 2 is installed on the mixing barrel 11 , and the stirring end of the stirring component 2 is located in the mixing barrel 11 for stirring the liquid medicine in the mixing barrel 11 .

[0038] The air jet assembly 3 is disposed at the inner bottom of the mixing barrel 11 and below the stirring assembly 2. The air jet assembly 3 is configured to blow air toward the inner bottom of the mixing barrel 11 to dissolve the undissolved drug powder particles that have settled to the bottom or to evenly disperse the undissolved powder in the drug solution.

[0039] When the above device is used for stirring a liquid medicine test, the jet assembly 3 can spray the settled medicine particles and powder, so that the medicine particles and powder move upward, fully dissolve or disperse, reduce the amount of sediment, and reduce the difficulty of cleaning the mixing barrel 11 after stirring.

[0040] The following is a detailed description of each component in the device.

[0041] like Figure 2 The housing assembly 1 may further include a heating base 14. The heating base 14 is disposed on the outer bottom of the mixing barrel 11 and can heat the liquid medicine in the mixing barrel 11.

[0042] like Figure 3 The jet assembly 3 includes an air pump 31 and a hollow disc box 32. The hollow disc box 32 is in the shape of a disc, which is a hollow box. The air pump 31 can pass high-pressure gas into the hollow disc box 32.

[0043] The hollow disc box 32 is mounted on the inner bottom of the mixing barrel 11. The air pump 31 is mounted outside the mixing barrel 11. The air supply pipe of the air pump 31 also penetrates the mixing barrel 11 and connects to the hollow disc box 32. The upper surface of the hollow disc box 32 has a plurality of air holes 3211. The gas output by the air pump 31 flows into the air holes 3211. The gas generated by the air pump 31 is vented to the bottom of the mixing barrel 11 through the air holes 3211 to blow away the sediment.

[0044] The multiple air holes 3211 in the hollow disk box 32 may originate from a plurality of air columns 321 located in an inner circle and a plurality of air columns 321 located in an outer circle. The air columns 321 may be perpendicular to the inner bottom surface of the mixing barrel 11. Each air column 321 has an air hole 3211 at its upper end, and the air columns 321 are connected to the main body of the hollow disk box 32. The double circle of air holes 3211 covers a large area and emits air evenly, effectively blowing away sediment. By adjusting the diameter of the air columns 321, air holes 3211 of appropriate diameter can be set, reducing the amount of particulate powder entering the air holes 3211. Any particulate powder that enters the air holes 3211 can also be blown out by the high-pressure gas.

[0045] like Figure 4 The air injection assembly 3 may further include an inner ring protection ring 33 and an outer ring protection ring 34. The inner ring protection ring 33 is mounted on the multiple air-inflating columns 321 of the inner ring, with each air-inflating column 321 extending upwardly through the inner ring protection ring 33. The outer ring protection ring 34 is mounted on the multiple air-inflating columns 321 of the outer ring, with each air-inflating column 321 extending upwardly through the outer ring protection ring 34. The air-inflating columns 321 have a certain height. The inner ring protection ring 33 and the outer ring protection ring 34 protect the air-inflating columns 321 and reduce the probability of damage to the air-inflating columns 321.

[0046] To reduce the accumulation of sediment around the air blast pillars 321, the inner ring protection ring 33, and the outer ring protection ring 34, the air jet assembly 3 also includes a cover plate 35. The cover plate 35 covers the inner ring protection ring 33 and the outer ring protection ring 34. The cover plate 35 defines multiple inner ring through-holes 351 and multiple outer ring through-holes 351. The multiple air blast pillars 321 of the inner ring are connected to the multiple inner ring through-holes 351. The multiple air blast pillars 321 of the outer ring are connected to the multiple outer ring through-holes 351. The cover plate 35 shields most of the air blast pillars 321 and the inner ring protection ring 33 and the outer ring protection ring 34. Sediment falls onto the cover plate 35 and is less likely to settle around the inner ring protection ring 33 and the outer ring protection ring 34, thus reducing sediment accumulation and improving sediment removal efficiency.

[0047] like Figure 5 The stirring assembly 2 may include a motor 21, a rotating shaft 22, and a plurality of stirring blades 23. The motor 21 is mounted on the mixing barrel 11, the motor 21 is connected to the rotating shaft 22, and the rotating shaft 22 penetrates into the mixing barrel 11 without contact. The plurality of stirring blades 23 are fixed on the rotating shaft 22. The plurality of stirring blades 23 are located in the mixing barrel 11. The rotating shaft 22 and the plurality of stirring blades 23 are both located above the cover plate 35. The stirring assembly 2 can efficiently stir the liquid medicine.

[0048] like Figure 6 The biopharmaceutical liquid test stirring device may further include a cleaning component 4. The cleaning component 4 includes a water-passing ring 41 and a water-passing frame 42. The water-passing ring 41 is installed above the mixing barrel 11. The water-passing ring 41 may be an annular tube. The water-passing ring 41 has a water inlet 411. The water-passing frame 42 is arranged inside the mixing barrel 11. The water-passing ring 41 is connected to the water-passing frame 42. The water-passing frame 42 may be an annular tube with four water-passing boxes 421 connected below. The water-passing ring 41 penetrates into the mixing barrel 11 through two conduits 412 and is seamlessly connected to the annular tube of the water-passing frame 42.

[0049] The water-passing racks 42 each have a plurality of spray heads 422 . Specifically, a plurality of spray heads 422 may be installed on the inner side of each water-passing box 421 .

[0050] like Figure 7 The four water-passing boxes 421 are evenly spaced apart, so that the multiple spray heads 422 are evenly arranged around the circumference of the stirring assembly 2. The water inlet 411 of the water-passing ring 41 is connected to a high-pressure water source, such as tap water, and water is sprayed toward the stirring assembly 2 from the multiple spray heads 422. Since the spray heads 422 can spray water mist over a large area, the water can also be sprayed toward the inner wall of the mixing barrel 11, thereby fully covering the stirring assembly 2 and the inner wall of the mixing barrel 11, so that they are fully cleaned, reducing the intensity of subsequent manual cleaning, or even eliminating the need for manual cleaning.

[0051] Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments, or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application should be included in the scope of protection of the present application.

Claims

1. A stirring device for biopharmaceutical liquid testing, characterized in that: It comprises a housing component (1), a stirring component (2) and an air jet component (3); The housing assembly (1) comprises a mixing barrel (11), a liquid inlet pipe (12) and a liquid outlet pipe (13); the liquid inlet pipe (12) is connected to the upper end of the mixing barrel (11); the liquid outlet pipe (13) is connected to the inner bottom of the mixing barrel (11); The stirring assembly (2) is mounted on the mixing barrel (11), and the stirring end of the stirring assembly (2) is located in the mixing barrel (11); The jet assembly (3) is arranged at the inner bottom of the mixing barrel (11) and is located below the stirring assembly (2); the jet assembly (3) is configured to blow air toward the inner bottom of the mixing barrel (11).

2. The biopharmaceutical liquid test stirring device according to claim 1, characterized in that: The housing assembly (1) further comprises a heating base (14); the heating base (14) is arranged on the outer bottom of the mixing barrel (11).

3. The biopharmaceutical liquid test stirring device according to claim 1, characterized in that: The jet assembly (3) comprises an air pump (31) and a hollow disc box (32); the hollow disc box (32) is arranged at the inner bottom of the mixing barrel (11); the air pump (31) is arranged outside the mixing barrel (11), and the air delivery pipe of the air pump (31) also penetrates the mixing barrel (11) and is connected to the hollow disc box (32); the upper surface of the hollow disc box (32) has a plurality of air holes (3211); the gas output by the air pump (31) flows into the air holes (3211).

4. The biopharmaceutical liquid test stirring device according to claim 3, characterized in that: The hollow disc box (32) has a plurality of air-blowing columns (321) located in the inner circle and a plurality of air-blowing columns (321) located in the outer circle, and each air-blowing column (321) has one air hole (3211).

5. The biopharmaceutical liquid test stirring device according to claim 4, characterized in that: The jet assembly (3) further comprises an inner ring protection ring (33) and an outer ring protection ring (34); the inner ring protection ring (33) is sleeved on a plurality of air-blowing columns (321) of the inner ring, and each air-blowing column (321) passes through the inner ring protection ring (33) upwards; The outer ring protection ring (34) is sleeved on a plurality of air-blowing columns (321) of the outer ring, and each air-blowing column (321) passes through the outer ring protection ring (34) upwards.

6. The biopharmaceutical liquid test stirring device according to claim 5, characterized in that: The jet assembly (3) further includes a cover plate (35); the cover plate (35) covers the inner ring protection ring (33) and the outer ring protection ring (34); the cover plate (35) is provided with a plurality of through holes (351) of the inner ring and a plurality of through holes (351) of the outer ring; the plurality of air columns (321) of the inner ring are connected one by one to the plurality of through holes (351) of the inner ring; and the plurality of air columns (321) of the outer ring are connected one by one to the plurality of through holes (351) of the outer ring.

7. The biopharmaceutical liquid test stirring device according to claim 6, characterized in that: The stirring assembly (2) comprises a motor (21), a rotating shaft (22) and a plurality of stirring blades (23); the motor (21) is mounted on the mixing barrel (11), the motor (21) is connected to the rotating shaft (22), and the rotating shaft (22) penetrates into the mixing barrel (11) without contact; the plurality of stirring blades (23) are fixed on the rotating shaft (22); the plurality of stirring blades (23) are located in the mixing barrel (11); the rotating shaft (22) and the plurality of stirring blades (23) are both located above the cover plate (35).

8. The biopharmaceutical liquid test stirring device according to claim 1, characterized in that: The biopharmaceutical liquid test stirring device further comprises a cleaning assembly (4); the cleaning assembly (4) comprises a water-passing ring (41) and a water-passing frame (42); the water-passing ring (41) is installed above the mixing barrel (11), and the water-passing frame (42) is arranged inside the mixing barrel (11); the water-passing ring (41) is connected to the water-passing frame (42); the water-passing ring (41) has a water inlet (411); the water-passing frame (42) has a plurality of spray heads (422), and the plurality of spray heads (422) are arranged around the circumference of the stirring assembly (2).

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