Auxiliary device for improving amino acid production efficiency
By setting up auxiliary devices for interlaced coils and spray parts in the fermentation tank, the rapid separation of amino acids and fermentation broth is achieved, the problem of amino acid crystal blockage is solved, and the fermentation production efficiency of various amino acids is improved.
Patent Information
- Application Number
- CN202422437520.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-10
- Publication Date
- 2025-08-22
- Estimated Expiration
- 2034-10-10
AI Technical Summary
In the prior art, when the concentration of amino acid products in the fermentation broth reaches a certain level, it is easy to crystallize and block the pipeline, resulting in low equipment utilization and low production efficiency. The prior art is limited to valine, which is not applicable to the production of other amino acids.
An auxiliary device is designed, including setting up multiple coils arranged at equal intervals in the tank, adjacent coils are connected interlaced, and sprayed parts with cross structures to achieve rapid separation of amino acids and fermentation broth, using alternate treatment of cold or hot water to achieve condensation and dissolution of amino acids, fixing the coils through supporting parts, and setting barrier parts to control flow direction.
It realizes rapid separation of amino acids and fermentation broth, improves the fermentation production efficiency of amino acids, avoids crystallization blockage, and is suitable for the production of a variety of amino acids.
Smart Images
Figure CN223255222U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of fermentation equipment, in particular to an auxiliary device for improving amino acid production efficiency. Background Art
[0002] Microbial fermentation is currently the preferred method for amino acid production. It utilizes microbial metabolism to directly ferment and synthesize amino acids using glucose as a raw material. It offers advantages such as low raw material costs, mild and easily controllable reaction conditions, and minimal pollution. However, in actual fermentation production, the accumulation of amino acid products is often subject to feedback inhibition. Furthermore, many amino acids have low solubility. When their concentration in the fermentation broth reaches a certain level, they tend to crystallize and clog pipelines, forcing fermentation to cease, resulting in low equipment utilization and low production efficiency.
[0003] When the valine concentration in the fermentation broth is ≥8.0%, the L-isoleucine concentration is ≥4.3%, the L-leucine concentration is ≥3.8%, and the L-threonine concentration is ≥11.5%, crystallization is likely to clog the pipeline. In the Chinese patent number CN2021110483959, entitled "A High-efficiency Valine Semi-continuous Fermentation Method and a Complete Set of Devices Therefor", it is disclosed that during valine fermentation, crystals are gradually floated to the upper layer of the fermentation broth and discharged from the fermentation tank, thereby improving production efficiency and fermentation tank utilization. However, this method is limited to valine and is not applicable to the production of many other amino acids.
[0004] In summary, the existing technology has obvious inconveniences and defects in actual use, so it is necessary to improve it. Utility Model Content
[0005] In view of the above-mentioned defects, the purpose of the present invention is to provide an auxiliary device for improving the production efficiency of amino acids, which can realize the rapid separation of amino acids and fermentation liquid, thereby improving the fermentation production efficiency of amino acids.
[0006] In order to achieve the above object, the utility model provides an auxiliary device for improving the production efficiency of amino acids, the auxiliary device is arranged in a tank body, and the auxiliary device includes a plurality of coils arranged at equal intervals from top to bottom in the tank body, adjacent coils are connected to each other, and adjacent layers of coils are staggered;
[0007] A spray component is provided in the tank body and is located above the coil; the spray component is in a cross structure, and a plurality of spray ports are arranged at the bottom of the spray component.
[0008] As an optimal technical solution, the coil located at the bottom is connected to a coil inlet connecting pipe, one end of which passes through the side wall of the tank body; the coil located at the top is connected to a coil outlet connecting pipe, one end of which passes through the side wall of the tank body.
[0009] As a preferred technical solution, the coil is fixed in the tank body by a supporting member, and the supporting member is configured as a retractable structure;
[0010] The supporting component includes a fixed frame, a sliding frame is provided inside the fixed frame, the end of the sliding frame is connected to the supporting frame, and a fixing plate is also provided on the supporting component. The fixing plate is an arc-shaped structure, and its curvature is adapted to the curvature of the side wall of the tank body. The fixing plate is fixed on the tank body.
[0011] As a preferred technical solution, the supporting component is a hollow structure.
[0012] As a preferred technical solution, the top of the spray component is connected to the third pipe opening of the tee pipe, and the other two pipe openings of the tee pipe are located outside the tank body and are respectively provided with a feed valve and a cleaning valve;
[0013] A detachable blocking component is provided at the center position of the three-way pipe, and the blocking component includes a pipe cover, a handle is provided on the top of the pipe cover, the pipe cover is connected to a fixed blocking plate, and a movable blocking plate is hinged at the bottom of the fixed blocking plate, and the movable blocking plate extends into the third pipe opening of the three-way pipe.
[0014] As a preferred technical solution, the height of the fixed baffle is 1 / 2 of the diameter of the tee pipe.
[0015] As a preferred technical solution, a corrosion-resistant rubber layer is provided at the third pipe opening of the three-way pipe.
[0016] As an optimal technical solution, the pipe opening of the feed valve provided on the three-way pipe is connected to the feed pipe, the pipe opening of the cleaning valve provided on the three-way pipe is connected to the cleaning pipe, and the third pipe opening of the three-way pipe is connected to the tank connecting pipe.
[0017] As a preferred technical solution, the bottom of the tank body is connected to a tank body discharge pipe, the tank body discharge pipe is connected to a fermentation liquid outlet pipe and an amino acid outlet pipe, the fermentation liquid outlet pipe is provided with a fermentation liquid outlet valve, and the amino acid outlet pipe is provided with an amino acid outlet valve.
[0018] As a preferred technical solution, a sight glass is provided on the tank body.
[0019] The utility model provides an auxiliary device for improving amino acid production efficiency, which can realize rapid separation of amino acids and fermentation liquid. The fermentation liquid from which the amino acids are separated can enter the fermentation tank again for further fermentation and cultivation, thereby improving the fermentation production efficiency of amino acids. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1A schematic diagram of the structure of an auxiliary device for improving the efficiency of amino acid production in this practical application;
[0021] Figure 2 for Figure 1 Enlarged view of the middle M;
[0022] Figure 3 This is a schematic diagram of the installation position of the barrier component;
[0023] Figure 4 It is the structural diagram of the coil;
[0024] Figure 5 is a structural diagram of the supporting component;
[0025] Figure 6 It is a structural diagram of the spray component;
[0026] In the picture:
[0027] 1-tank body, 2-tee pipe, 21-feed valve, 22-cleaning valve, 23-blocking component, 231-pipe cover, 232-movable baffle plate, 233-fixed baffle plate, 234-handle, 24-feed pipe, 25-cleaning pipe, 26-tank connecting pipe, 27-rubber layer, 3-coil, 31-coil inlet connecting pipe, 32-coil outlet connecting pipe, 4-support component, 41-fixed frame, 42-sliding frame, 43-support frame, 44-fixed plate, 5-spraying component, 6-tank discharge pipe, 7-fermentation liquid outlet valve, 8-amino acid outlet valve. DETAILED DESCRIPTION
[0028] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.
[0029] Example 1:
[0030] See also Figure 1 and Figure 3 The present invention provides an auxiliary device for improving amino acid production efficiency, which is disposed in a tank body 1. The auxiliary device includes a plurality of coils 3 arranged at equal intervals from top to bottom in the tank body 1. Adjacent coils 3 are connected to each other. The coils 3 at the bottom are connected to a coil inlet connecting pipe 31, one end of which passes through the side wall of the tank body 1. The coils 3 at the top are connected to a coil outlet connecting pipe 32, one end of which passes through the side wall of the tank body 1. Preferably, the coil inlet connecting pipe 31 is located on the opposite side of the coil outlet connecting pipe 32.
[0031] The two adjacent layers of coils 3 are staggered. This arrangement allows a larger area of the coils 3 to contact the fermentation liquid containing amino acids, greatly increasing the amount of amino acids condensed on the coils 3 when cooled.
[0032] The coil 3 is fixed in the tank 1 by the support member 4. Figure 5 The support component 4 is provided with a hollow structure inside, and the connecting pipes between two adjacent layers of coils 3 can be connected through the hollow structure of the support component 4. This arrangement not only reduces the weight of the support component 4, but also makes the connection between two adjacent layers of coils 3 smoother and more convenient. In order to adapt to the structure of the staggered arrangement of two adjacent layers of coils 3, the support component 4 is provided with a retractable structure. Specifically, the support component 4 includes a fixed frame 41, and a sliding frame 42 is provided inside the fixed frame 41. The end of the sliding frame 42 is connected to a support frame 43. The sliding distance of the sliding frame 42 can be adjusted according to the needs of the coil 3 setting position, so that the support frame 43 can support the coil 3 more stably. A fixing plate 44 is also provided on the support component 4. The fixing plate 44 is an arc-shaped structure, and its curvature is adapted to the curvature of the side wall of the tank body 1. The fixing plate 44 can be connected to the tank body 1 by bolts, or it can be adhered to the tank body 1 using existing adhesive technology.
[0033] The coil 3 can be fixed on the inner wall of the tank body 1 through the support component 4 to prevent the coil 3 from shaking and causing danger during operation.
[0034] See also Figure 1 and Figure 6 A spraying component 5 is provided in the tank body 1 and is located above the coil 3. The spraying component 5 is in a cross structure, and a plurality of spray ports 51 are arranged at the bottom of the spraying component 5. By arranging the spraying component in a cross structure, the fermentation liquid containing amino acids can be sprayed more evenly throughout the tank body 1.
[0035] The top of the spray component 5 is connected to the third pipe opening of the three-way pipe 2. The other two pipe openings of the three-way pipe 2 are located outside the tank body 1 and are respectively provided with a feed valve 21 and a cleaning valve 22.
[0036] See also Figures 1 to 3 A detachable blocking member 23 is provided at the center of the tee pipe 2. The blocking member 23 includes a pipe cover 231 with a handle 234 on top. The pipe cover 231 is connected to a fixed blocking plate 233, the height of which is 1 / 2 of the diameter of the tee pipe 2.
[0037] The bottom of the fixed baffle plate 233 is hinged with a movable baffle plate 232, which extends into the third pipe opening of the tee pipe 2. In order to prevent the movable baffle plate 232 from swinging left and right and causing collision damage to the tee pipe 2, a corrosion-resistant rubber layer 27 is provided at the third pipe opening of the tee pipe 2.
[0038] The pipe opening of the feed valve 21 on the three-way pipe 2 is connected to the feed pipe 24 , the pipe opening of the cleaning valve 22 on the three-way pipe 2 is connected to the cleaning pipe 25 , and the third pipe opening of the three-way pipe 2 is connected to the tank connecting pipe 26 .
[0039] The bottom of the tank body 1 is connected to a tank body discharge pipe 6, and the tank body discharge pipe 6 is connected to a fermentation liquid outlet pipe and an amino acid outlet pipe. The fermentation liquid outlet pipe is provided with a fermentation liquid outlet valve 7, and the amino acid outlet pipe is provided with an amino acid outlet valve 8.
[0040] During specific operation, the feed valve 21 on the feed pipe 24 is opened, and the fermentation liquid outlet valve 7 is opened at the same time. At this time, the cleaning valve 22 is closed, and the fermentation liquid containing amino acids passes through the feed pipe 24. Under the action of the movable blocking plate 232, the fermentation liquid containing amino acids is smoothly passed into the tank body 1. The movable blocking plate 232 can prevent the fermentation liquid containing amino acids from entering the cleaning pipe 25.
[0041] The fermentation liquid containing amino acids is evenly sprayed on the coils 3 of each layer through the multiple spray ports 51 on the spray component 5. At this time, cold water is introduced into the coils 3. After being cooled, the amino acids quickly condense and precipitate on the coils 2, thereby achieving rapid separation of the amino acids and the fermentation liquid. The fermentation liquid falls to the bottom of the tank body 1, is discharged through the tank body discharge pipe 6 and the fermentation liquid outlet valve 7, and re-enters the fermentation tank to continue fermentation and cultivation.
[0042] After the feeding is completed, the feed valve 21 and the fermentation liquid outlet valve 7 are closed, and hot water or steam is passed into the coil 3. The temperature of the coil 3 increases, and the amino acids attached to the coil 3 are dissolved. The cleaning valve 22 is opened, and a small amount of clean hot water is passed for flushing. Then, the amino acid outlet valve 8 is opened to discharge the dissolved amino acid solution out of the tank body 1 and enter the subsequent production link.
[0043] At the end of production, alkaline solution or acid solution can be introduced through the cleaning valve 22 to clean the tank body 1 and the coil 3.
[0044] In order to facilitate viewing of the situation inside the tank body 1, a sight glass may be provided on the tank body 1, and a manhole may also be provided for operators to inspect and clean the crystals remaining in the tank body.
[0045] This device can be used for fermentation of amino acids with low solubility, such as L-isoleucine, valine, L-leucine, and L-threonine. Valine concentrations ≥8.0%, isoleucine concentrations ≥4.3%, leucine concentrations ≥3.8%, and threonine concentrations ≥11.5% are prone to crystallization. Using this device when fermentation reaches these amino acid concentrations can significantly improve amino acid fermentation production efficiency.
[0046] The utility model provides an auxiliary device for improving amino acid production efficiency, which can realize rapid separation of amino acids and fermentation liquid. The fermentation liquid from which the amino acids are separated can enter the fermentation tank again for further fermentation and cultivation, thereby improving the fermentation production efficiency of amino acids.
[0047] Of course, the present invention may have many other embodiments. Without departing from the spirit and essence of the present invention, technicians familiar with the field can make various corresponding changes and modifications based on the present invention, but these corresponding changes and modifications should all fall within the scope of protection of the claims attached to the present invention.
Claims
1. An auxiliary device for improving amino acid production efficiency, the auxiliary device is arranged in a tank (1), characterized in that: The auxiliary device comprises a plurality of coils (3) arranged at equal intervals from top to bottom in the tank body (1), adjacent coils (3) are connected to each other, and two adjacent layers of coils (3) are staggered. A spray component (5) is provided in the tank body (1), and the spray component (5) is located above the coil (3); the spray component (5) is in a cross structure, and a plurality of spray ports (51) are arranged at the bottom of the spray component (5).
2. An auxiliary device for improving amino acid production efficiency according to claim 1, characterized in that: The coil (3) at the bottom is connected to a coil inlet connecting pipe (31), one end of which passes through the side wall of the tank body (1); the coil (3) at the top is connected to a coil outlet connecting pipe (32), one end of which passes through the side wall of the tank body (1).
3. The auxiliary device for improving amino acid production efficiency according to claim 1, characterized in that: The coil (3) is fixed in the tank body (1) via a supporting component (4), and the supporting component (4) is configured as a telescopic structure; The support component (4) includes a fixed frame (41), a sliding frame (42) is provided inside the fixed frame (41), and the end of the sliding frame (42) is connected to the support frame (43). The support component (4) is also provided with a fixing plate (44), and the fixing plate (44) is an arc-shaped structure, and its curvature is adapted to the curvature of the side wall of the tank body (1). The fixing plate (44) is fixed on the tank body (1).
4. The auxiliary device for improving amino acid production efficiency according to claim 3, characterized in that: The supporting component (4) is a hollow structure.
5. The auxiliary device for improving amino acid production efficiency according to claim 1, characterized in that: The top of the spray component (5) is connected to the third pipe opening of the three-way pipe (2), and the other two pipe openings of the three-way pipe (2) are located outside the tank body (1) and are respectively provided with a feed valve (21) and a cleaning valve (22); A detachable blocking component (23) is provided at the center of the three-way pipe (2), and the blocking component (23) includes a pipe cover (231), a handle (234) is provided on the top of the pipe cover (231), and the pipe cover (231) is connected to a fixed blocking plate (233), and a movable blocking plate (232) is hinged at the bottom of the fixed blocking plate (233), and the movable blocking plate (232) extends into the third pipe opening of the three-way pipe (2).
6. The auxiliary device for improving amino acid production efficiency according to claim 5, characterized in that: The height of the fixed blocking plate (233) is 1 / 2 of the diameter of the three-way pipe (2).
7. The auxiliary device for improving amino acid production efficiency according to claim 5, characterized in that: A corrosion-resistant rubber layer (27) is provided at the third pipe opening of the three-way pipe (2).
8. The auxiliary device for improving amino acid production efficiency according to claim 5, characterized in that: The pipe opening of the feed valve (21) provided on the three-way pipe (2) is connected to the feed pipe (24), the pipe opening of the cleaning valve (22) provided on the three-way pipe (2) is connected to the cleaning pipe (25), and the third pipe opening of the three-way pipe (2) is connected to the tank connecting pipe (26).
9. An auxiliary device for improving amino acid production efficiency according to any one of claims 1 to 8, characterized in that: The bottom of the tank body (1) is connected to a tank body discharge pipe (6), and the tank body discharge pipe (6) is connected to a fermentation liquid outlet pipe and an amino acid outlet pipe. The fermentation liquid outlet pipe is provided with a fermentation liquid outlet valve (7), and the amino acid outlet pipe is provided with an amino acid outlet valve (8).
10. The auxiliary device for improving amino acid production efficiency according to claim 9, characterized in that: A sight glass is provided on the tank body (1).