Clamping assembly for preparing artificial blood vessel

Abstract

The utility model provides a clamping assembly for preparing an artificial blood vessel, and relates to the technical field of artificial blood vessel preparation. The clamping assembly comprises an anti-sticking film and a heat shrink tube, and the anti-sticking film can be curled into a barrel shape and wraps the surface of the artificial blood vessel; the heat shrink tube is used for being arranged on the outer wall of a barrel-shaped anti-adherent film wrapping the artificial blood vessel in a sleeving mode. An artificial blood vessel can be firmly clamped for heat treatment, and the artificial blood vessel can be conveniently taken out from the clamping assembly.

Description

Technical Field

[0001] The present application relates to the technical field of artificial blood vessel preparation, and in particular to a clamping assembly for preparing artificial blood vessels. Background Art

[0002] Artificial blood vessels are medical devices used to treat vascular diseases. They are often used to replace or repair damaged blood vessels and are mostly artificially manufactured from synthetic materials such as nylon, polyester, and polytetrafluoroethylene. However, these artificial synthetic materials are relatively rigid and have poor biocompatibility, making them less suitable for the preparation of small-caliber blood vessels (diameter ≤ 6 mm). It has been reported that small-caliber blood vessels (inner diameter ≤ 6 mm) are more suitable for preparation using small intestinal submucosa (SIS). Generally, the small intestinal submucosa is coiled and then fixed with sutures. However, studies have shown that when sutured with microsutures, the degradation of the small intestinal submucosa causes the microsutures to be exposed to the blood, which can easily cause embolism.

[0003] The inventors of the present application have discovered that by wrapping the small intestinal submucosa around a polytetrafluoroethylene rod, clamping it with a clamping mold, and then performing a heat treatment, the layers of the resulting artificial blood vessel can be relatively fixed.

[0004] Based on this, the present application provides a clamping assembly for preparing an artificial blood vessel. Utility Model Content

[0005] The present application provides a clamping assembly for preparing an artificial blood vessel, which can firmly clamp the artificial blood vessel for heat treatment and can easily remove the artificial blood vessel from the clamping assembly.

[0006] This application is implemented as follows:

[0007] The present application provides a clamping assembly for preparing an artificial blood vessel, comprising:

[0008] an anti-adhesive film sheet, which can be rolled into a cylindrical shape and wrapped around the surface of the artificial blood vessel; and

[0009] A heat shrink tube is used to be sleeved on the outer wall of the cylindrical anti-adhesion film sheet that wraps the artificial blood vessel.

[0010] In a possible embodiment, the anti-adhesion film is a polytetrafluoroethylene film.

[0011] In a possible implementation manner, the thickness of the polytetrafluoroethylene membrane is 0.1-0.5 mm.

[0012] In a possible embodiment, the length of the heat shrink tube is greater than the length of the release film.

[0013] In a possible embodiment, at least one end of the heat shrinkable tube is provided with a fracture, the fracture is arranged along the length direction of the heat shrinkable tube, and the fracture runs through the inner wall and the outer wall of the heat shrinkable tube.

[0014] In a possible implementation, the end of the heat shrink tube is provided with two parallel fractures, and the distance between the two fractures is 10% to 30% of the circumference of the heat shrink tube.

[0015] In a possible implementation, the length of the heat shrink tube is L1, the length of the anti-adhesive film is L2, and the length of the fracture is less than or equal to L2-L1.

[0016] In one possible embodiment, the heat shrinkable tube is a fluoroethylene-ethylene copolymer heat shrinkable tube, a polytetrafluoroethylene heat shrinkable tube, a polyetheretherketone heat shrinkable tube, or a polyethylene heat shrinkable tube.

[0017] The embodiments of the present application have at least the following beneficial effects:

[0018] The clamping assembly for preparing an artificial blood vessel in an embodiment of the present application is constructed by wrapping an anti-adhesive film around the surface of the artificial blood vessel so that the layers of the artificial blood vessel are in close contact with each other. A heat shrink tubing is then placed over the cylindrical anti-adhesive film to maintain the cylindrical shape of the anti-adhesive film relatively fixed. The clamping assembly holding the artificial blood vessel is then heat-treated. The heat shrink tubing shrinks at a certain temperature, causing the layers of the artificial blood vessel to adhere more tightly to each other, thereby allowing the layers to react fully and increasing the bonding strength between the layers, making the artificial blood vessel less likely to fall off. Furthermore, because the anti-adhesive film is placed between the artificial blood vessel and the heat shrink tubing, the two are not in direct contact. After the heat treatment, the heat shrink tubing and the anti-adhesive film can be easily removed. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following is a brief introduction to the drawings required for use in the embodiments. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without creative work.

[0020] Figure 1 A cross-sectional view in a first direction of the clamping assembly of an embodiment of the present application clamping an artificial blood vessel;

[0021] Figure 2 It is a cross-sectional view in the second direction of the clamping assembly of the embodiment of the present application clamping an artificial blood vessel.

[0022] Icons: 10-clamping assembly; 11-anti-stick film; 12-heat shrink tubing; 121-fracture; 20-polytetrafluoroethylene rod; 30-artificial blood vessel. DETAILED DESCRIPTION

[0023] To make the objectives, technical solutions, and advantages of the embodiments of the present application more clear, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Generally, the components of the embodiments of the present application described and shown in the drawings herein can be arranged and designed in various different configurations.

[0024] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the present application for protection, but merely represents selected embodiments of the present application. All other embodiments obtained by persons of ordinary skill in the art based on the embodiments in the present application without creative work are within the scope of protection of the present application.

[0025] In the description of this application, it should be noted that the terms "upper," "lower," "inner," and "outer" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, or the orientations or positional relationships in which the product of this application is typically placed when in use. These terms are intended solely to facilitate the description of this application and simplify the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," and "third," etc., are used solely to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0026] It should also be noted that, in the description of this application, unless otherwise expressly specified or limited, the terms "disposed," "installed," and "connected" should be understood broadly. For example, they may refer to fixed connections, detachable connections, or integral connections; they may refer to direct connections, indirect connections through an intermediate medium, or internal connections between two components. Those skilled in the art will understand the specific meanings of these terms in this application based on the specific circumstances. Example

[0027] This embodiment provides a clamping assembly 10 for preparing an artificial blood vessel, which includes an anti-adhesion film 11 and a heat shrink tube 12.

[0028] The anti-adhesive film sheet 11 can be rolled into a cylindrical shape and wrapped around the surface of the artificial blood vessel 30. The heat shrink tube 12 is used to be sleeved on the outer wall of the cylindrical anti-adhesive film sheet 11 wrapped around the artificial blood vessel 30. Exemplarily, the heat shrink tube 12 is a fluoroethylene-ethylene copolymer heat shrink tube, a polytetrafluoroethylene heat shrink tube 12, a polyetheretherketone heat shrink tube 12, or a polyethylene heat shrink tube 12.

[0029] For example, the artificial blood vessel 30 is formed by winding the decellularized small intestinal submucosa, wherein the small intestinal submucosa is wound on the surface of a polytetrafluoroethylene rod 20. The anti-adhesive film sheet 11 is rolled into a cylindrical shape to tightly wrap the artificial blood vessel 30 wrapped on the surface of the polytetrafluoroethylene rod 20, so that the layers of the artificial blood vessel 30 are in close contact with each other. The heat shrink tubing 12 is sleeved on the cylindrical anti-adhesive film sheet 11 to maintain the cylindrical shape of the anti-adhesive film sheet 11 in a relatively fixed state. The clamping assembly 10 holding the artificial blood vessel 30 is then heat-treated. The heat shrink tubing 12 shrinks at a certain temperature, making the layers of the artificial blood vessel 30 more closely attached to each other, thereby fully reacting with each other and increasing the bonding strength between the layers, making the artificial blood vessel 30 less likely to fall off. Moreover, the anti-adhesive film 11 separates the artificial blood vessel 30 and the heat shrink tube 12, so that the heat shrink tube 12 is not in direct contact with the artificial blood vessel 30. The anti-adhesive film 11 has anti-adhesive properties. After heat treatment, it is convenient to remove the heat shrink tube 12 from the surface of the anti-adhesive film 11 without damaging the artificial blood vessel 30. After the heat shrink tube 12 is removed, it is also convenient to remove the anti-adhesive film 11 without damaging the artificial blood vessel 30.

[0030] For example, when removing the heat shrink tube 12, a knife can be used to cut the heat shrink tube 12, and then remove the heat shrink tube 12. Since the surface of the artificial blood vessel 30 is also wrapped with the anti-adhesion film 11, it is not easy to scratch the surface of the artificial blood vessel 30.

[0031] In one embodiment, at least one end of the heat shrink tube 12 is provided with a broken slit 121. That is, the broken slit 121 may be provided at one end of the heat shrink tube 12, or at both ends of the heat shrink tube 12. The broken slit 121 is provided along the length of the heat shrink tube 12 and penetrates both the inner and outer walls of the heat shrink tube 12. Since the broken slit 121 is provided at the end of the heat shrink tube 12, the end provided with the broken slit 121 can be relatively enlarged. When the cylindrical anti-adhesive film 11 wrapped with the artificial blood vessel 30 needs to be inserted into the heat shrink tube 12, it can be inserted from the end with the broken slit 121, which is more convenient. Furthermore, after the heat treatment is completed, the heat shrink tube 12 shrinks, and the heat shrink tube 12 can be opened from the end with the broken slit 121 along the broken slit 121.

[0032] Optionally, the anti-adhesive film 11 is a polytetrafluoroethylene (PTFE) film. PTFE has a low coefficient of friction and lubrication, providing excellent anti-adhesive properties. Furthermore, the carbon-fluorine bonds in PTFE's molecular structure are very stable, giving it excellent chemical inertness and thermal stability, making it less likely to deform or react during heat treatment.

[0033] For example, the thickness of the polytetrafluoroethylene membrane is 0.1 to 0.5 mm, such as 0.1 mm, 0.2 mm, 0.3 mm, 0.4 mm, or 0.5 mm. The polytetrafluoroethylene membrane of this embodiment is thinner and more flexible, making it easier to wrap around the outer wall of the small-sized artificial blood vessel 30 and clamp the artificial blood vessel 30.

[0034] The heat shrink tube 12 has a length of L1, the release film 11 has a length of L2, and the length of the fracture 121 is less than or equal to L2-L1. The portion of the heat shrink tube 12 with the fracture 121 is defined as the first portion, and the portion without the fracture 121 is defined as the second portion. When the heat shrink tube 12 is sleeved over the outer wall of the release film 11, the release film 11 corresponds to the second portion of the heat shrink tube 12, and the fracture 121 does not cover the surface of the release film 11. The heat shrink tube 12 shrinks during the heat treatment process. The second portion of the heat shrink tube 12 is a complete cylindrical shape, which better ensures that the entire artificial blood vessel 30 is subjected to the contraction force of the heat shrink tube 12, and the layers react and connect more tightly. Furthermore, it is convenient to open the heat shrink tube 12 from the fracture 121.

[0035] Optionally, the end of the heat shrink tube 12 is provided with two parallel slits 121, with the distance between the slits 121 being 10% to 30% of the circumference of the heat shrink tube 12. With these two parallel slits 121, the heat shrink tube 12 can be severed along the slits 121 by grasping the portion between the slits 121 and pulling in opposite directions without the aid of other tools. If the distance between the slits 121 is too short, the portion between the slits 121 is easily torn apart. If the distance between the slits 121 is too long, greater force is required to tear the portion through the slits 121. Therefore, the distance between the slits 121 is preferably 10% to 30% of the circumference of the heat shrink tube 12.

[0036] In summary, the clamping assembly 10 for preparing an artificial blood vessel according to an embodiment of the present application is constructed by wrapping the anti-adhesive film 11 around the surface of the artificial blood vessel 30, thereby ensuring close contact between the layers of the artificial blood vessel 30. The heat shrink tubing 12 is then placed over the cylindrical anti-adhesive film 11, thereby maintaining the cylindrical shape of the anti-adhesive film 11 in a relatively fixed state. The clamping assembly 10 holding the artificial blood vessel 30 is then subjected to a heat treatment, causing the heat shrink tubing 12 to shrink at a certain temperature, thereby making the layers of the artificial blood vessel 30 more closely attached to each other, thereby allowing for sufficient reaction between the layers and increasing the bonding strength between the layers, making the artificial blood vessel 30 less likely to fall off. Furthermore, since the anti-adhesive film 11 is located between the artificial blood vessel 30 and the heat shrink tubing 12, the two are not in direct contact. After the heat treatment, the heat shrink tubing 12 and the anti-adhesive film 11 can be easily removed.

[0037] The above are merely preferred embodiments of the present application and are not intended to limit the present application. Those skilled in the art will readily appreciate that various modifications and variations are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present application shall be included within the scope of protection of the present application.

Claims

1. A clamping assembly for preparing an artificial blood vessel, characterized in that: include: An anti-adhesive film sheet, which can be rolled into a cylindrical shape and wrapped around the surface of the artificial blood vessel; as well as A heat shrink tube is used to be sleeved on the outer wall of the cylindrical anti-adhesion film sheet that wraps the artificial blood vessel.

2. The clamping assembly for preparing an artificial blood vessel according to claim 1, characterized in that: The anti-sticking film is a polytetrafluoroethylene film.

3. The clamping assembly for preparing an artificial blood vessel according to claim 2, characterized in that: The thickness of the polytetrafluoroethylene diaphragm is 0.1-0.5 mm.

4. The clamping assembly for preparing an artificial blood vessel according to any one of claims 1 to 3, characterized in that: The length of the heat shrink tube is greater than the length of the anti-adhesion film.

5. The clamping assembly for preparing an artificial blood vessel according to claim 4, characterized in that: At least one end of the heat shrink tube is provided with a broken crack, the broken crack is arranged along the length direction of the heat shrink tube, and the broken crack runs through the inner wall and the outer wall of the heat shrink tube.

6. The clamping assembly for preparing an artificial blood vessel according to claim 5, characterized in that: The end of the heat shrink tube is provided with two parallel broken cracks, and the distance between the two broken cracks is 10% to 30% of the circumference of the heat shrink tube.

7. The clamping assembly for preparing an artificial blood vessel according to claim 5, characterized in that: The length of the heat shrink tube is L1, the length of the anti-adhesion film is L2, and the length of the fracture is less than or equal to L2-L1.

8. The clamping assembly for preparing an artificial blood vessel according to any one of claims 1 to 3, characterized in that: The heat shrink tube is a fluorinated ethylene copolymer heat shrink tube, a polytetrafluoroethylene heat shrink tube, a polyetheretherketone heat shrink tube or a polyethylene heat shrink tube.

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