Slide fixing device, scanning device and pathological section scanner

Abstract

The utility model belongs to the technical field of pathological scanning, and relates to a slide fixing device, a scanning device and a pathological section scanner, the slide fixing device comprises a mounting seat, a first clamping piece, a second clamping piece and a clamping switch assembly, and the mounting seat is provided with a supporting surface for placing a slide; the first clamping piece and the second clamping piece are oppositely mounted on the mounting seat; the first clamping piece is provided with at least one first clamping part, and the second clamping piece is provided with at least one second clamping part; in the length direction of the slide, the ratio of the length of a clamping area jointly formed by the first clamping part and the second clamping part to the length of the slide is greater than or equal to 1 / 2; under the action of the clamping switch assembly, the first clamping piece and the second clamping piece are relatively close to each other so as to clamp different parts of the slide on the supporting surface from the two opposite sides of the slide through the first clamping part and the second clamping part, or the first clamping piece and the second clamping piece are relatively far away from each other so as to release clamping of the slide. According to the utility model, the fixing and mounting efficiency of the slide is high, the energy consumption is low, and safety and stability are realized.

Description

Technical Field

[0001] The utility model relates to the technical field of pathology scanning, in particular to a slide fixing device, a scanning device and a pathology slice scanner. Background Art

[0002] A pathology slide scanner is a medical device that rapidly scans the entire slide in all directions, converting the traditional pathology information stored on the slide into digital form. Slide scanning involves taking high-precision, macro-scale images of the tissue sample enclosed on the slide to create a digital image of the entire slide for interpretation on a computer screen.

[0003] Existing pathology slide scanners typically require the slide to be scanned to be fixed on the scanning platform to ensure sufficient stability during high-speed motion and to ensure image quality. Currently, there are several main methods for securing slides on the scanning platform: First, Z-axis compression is used, but this method often requires manual operation, is inefficient, unsafe, and prone to breakage; second, a tray supports the slide, which is structurally complex, increases the control requirements for slide mounting precision, and makes stability difficult to ensure; and third, vacuum suction requires an additional power source and consumes a lot of energy. Utility Model Content

[0004] The purpose of the utility model is to solve at least one of the technical problems of low efficiency, low safety and stability, and high energy consumption in the fixed installation of glass slides.

[0005] The present invention provides a slide fixing device, which adopts the following technical solution:

[0006] The slide fixing device includes a mounting base, a first clamp, a second clamp, and a clamping switch assembly. The mounting base is provided with a support surface for placing the slide. The first clamp and the second clamp are mounted relative to the mounting base and together with the support surface form a clamping space for placing the slide.

[0007] The first clamping member is provided with at least one first clamping portion on a side facing the clamping space, and the second clamping member is provided with at least one second clamping portion on a side facing the clamping space; in the length direction of the glass slide, the ratio of the length of the clamping area formed by the first clamping portion and the second clamping portion to the length of the glass slide is greater than or equal to 1 / 2;

[0008] Under the action of the clamping switch assembly, the first clamp and the second clamp are relatively close to each other, so as to clamp different parts of the glass slide in the clamping space from opposite sides of the glass slide through the first clamp and the second clamp, or the first clamp and the second clamp are relatively far away from each other, so as to release the clamping of the glass slide in the clamping space.

[0009] In some embodiments of the present invention, each of the first clamping parts and each of the second clamping parts are in contact with the corresponding side surface of the glass slide at least at one point;

[0010] And / or, the mounting seat is provided with an inlet and outlet for placing the glass slide into the supporting surface, the inlet and outlet being in communication with the clamping space; the inlet and outlet of the mounting seat corresponds to the first clamping portion and / or the second clamping portion;

[0011] And / or, the first clamping portion and the second clamping portion are both spaced apart in a line along the length direction of the glass slide, and the first clamping portion and the second clamping portion are arranged opposite to each other.

[0012] In some embodiments of the present invention, three of the first clamping parts and three of the second clamping parts are provided, and the three first clamping parts are used to clamp the front end, the middle part and the parts corresponding to the inlet and outlet of the glass slide respectively; the three second clamping parts are used to clamp the front end, the middle part and the parts corresponding to the inlet and outlet of the glass slide respectively.

[0013] In some embodiments of the present invention, at least one of the first clamp and the second clamp is a movable clamp;

[0014] The clamping switch assembly includes:

[0015] The guide member is provided with a guide surface; the guide surface includes an opening holding surface and a clamping holding surface; the opening holding surface and the clamping holding surface are arranged in sequence along the feeding direction of the glass slide;

[0016] a switch member, disposed on the movable clamp;

[0017] When the switch member contacts the opening holding surface, a gap exists between the movable clamp and the glass slide in the clamping space, thereby releasing the clamping of the glass slide;

[0018] When the switch member abuts against the clamping and holding surface, the first clamping portion and the second clamping portion jointly clamp the glass slide.

[0019] In some embodiments of the present invention, the guide surface further includes a transition arc surface, the transition arc surface being located between the opening holding surface and the clamping holding surface; opposite ends of the transition arc surface are tangent to the opening holding surface and the clamping holding surface respectively;

[0020] When the switch member moves relative to the guide member along the feeding direction of the glass slide and the switch member abuts against the transition arc surface, the movable clamp gradually approaches the glass slide in the clamping space to finally clamp the glass slide;

[0021] When the switch member moves relative to the guide member along the retracting direction of the glass slide and the switch member abuts against the transition arc surface, the clamping force of the movable clamp on the glass slide in the clamping space gradually decreases to eventually release the clamping of the glass slide;

[0022] And / or, the switch member is a cam, and when the guide member abuts against the switch member, the wheel surface of the cam abuts against the guide surface.

[0023] In some embodiments of the present invention, the first clamp is a movable clamp, and the second clamp is fixedly mounted on the mounting seat;

[0024] The clamping switch assembly further includes a linear motion assembly, through which the first clamp is slidably connected to the mounting seat so as to be able to move closer to or farther away from the second clamp;

[0025] And / or, the clamping switch assembly further includes an elastic buffer member, which is arranged between the mounting seat and the first clamping member and is used to provide a buffering force for the opening or clamping of the first clamping member.

[0026] In order to solve the above technical problems, the embodiment of the present invention further provides a scanning device, which adopts the following technical solution: the scanning device includes

[0027] Stage assembly, used for carrying slides;

[0028] A scanning component, configured to scan a passing glass slide to obtain a digital image of a tissue slice on the glass slide; and

[0029] The above-mentioned glass slide fixing device, the mounting base of the glass slide fixing device is arranged on the stage assembly.

[0030] In some embodiments of the present invention, the scanning device further comprises:

[0031] A base, provided with a scanning channel;

[0032] When the clamping switch assembly of the slide fixing device includes a guide member and a switch member, the guide member is provided on the base near the entrance of the scanning channel; the guide surface of the guide member is located on the side away from the stage assembly.

[0033] In some embodiments of the present invention, the stage assembly includes a focusing stage and a stage for placing a glass slide, the stage being the mounting seat; the mounting seat is mounted on the top of the focusing stage;

[0034] And / or, a mounting hole is provided on the mounting base at a position corresponding to the support surface of the mounting base; the mounting hole is communicated with the clamping space and has a built-in backlight source.

[0035] In order to solve the above technical problems, the embodiment of the present utility model further provides a pathology slide scanner, which adopts the following technical solution: the pathology slide scanner includes the above slide fixing device;

[0036] Alternatively, the pathology slice scanner includes the above-mentioned scanning device.

[0037] Compared with the prior art, the slide fixing device, scanning device, and pathology slide scanner provided by the embodiments of the present invention have the following beneficial effects:

[0038] The glass slide fixing device automatically controls the relative approach or distance between the first clamp and the second clamp through the action of a mechanical clamping switch component, which is beneficial to improving the efficiency of glass slide fixing and installation on the one hand, and reducing energy consumption during the glass slide installation process on the other hand; in addition, in the length direction of the glass slide, the ratio between the length of the clamping area jointly formed by the first clamping part of the first clamp and the second clamping part of the second clamp and the length of the glass slide is greater than or equal to 1 / 2, which can effectively ensure that the first clamp and the second clamp stably clamp the glass slide on the one hand, and on the other hand, reduce the contact surface of the first clamp, the second clamp and the glass slide through partial contact between the first clamp and the second clamp and the glass slide, thereby reducing the contact area and contact probability of the first clamp, the second clamp and the glue, which is beneficial to reducing the breakage rate of the glass slide and realizing safe and stable transportation of the glass slide. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the solutions in the present invention, the following briefly introduces the drawings required for the description of the embodiments. Obviously, the drawings described below are some embodiments of the present invention or corresponding prior art. For those skilled in the art, other drawings can be obtained based on these drawings without inventive work. Among them:

[0040] Figure 1 This is a schematic diagram of the three-dimensional structure of a glass slide fixing device in a clamping state in an example of the present invention; in this figure, the glass slide fixing device clamps the glass slide;

[0041] Figure 2 This is a schematic diagram of the three-dimensional structure of a guide member for clamping a switch assembly in one example of the present utility model;

[0042] Figure 3 This is a schematic diagram of the three-dimensional structure of a glass slide fixing device in one example of the present invention from one viewing angle; the switch member of the clamping switch assembly is omitted in this diagram;

[0043] Figure 4 yes Figure 3 A schematic diagram of the three-dimensional structure of the middle slide fixing device from another perspective;

[0044] Figure 5 yes Figure 3 A schematic diagram of the three-dimensional structure of the slide fixing device from another perspective; and in this figure, the slide fixing device is in an open state to release the clamping of the slide;

[0045] Figure 6 This is a schematic diagram of a three-dimensional structure of a scanning device in an example of the present invention; in this figure, the stage assembly is completely in the scanning cavity;

[0046] Figure 7 This is a schematic diagram of another three-dimensional structure of a slide fixing device in an example of the present invention; in this figure, the stage assembly is in the initial position, and the slide fixing device is in the open state for inserting a slide;

[0047] Figure 8 This is a schematic diagram of another three-dimensional structure of a slide fixing device in an example of the present invention; in this figure, the stage assembly moves a short distance away from the initial position into the scanning cavity, and the slide fixing device is in a clamping state;

[0048] Figure 9 This is a schematic diagram of a three-dimensional structure of an example of the present invention when the slide fixing device and the stage assembly cooperate; in this figure, the slide fixing device releases the grip on the slide and is in an open state;

[0049] Figure 10 This is another three-dimensional structural diagram of the glass slide fixing device and the stage assembly in an example of the present invention; in this figure, the glass slide fixing device clamps the glass slide and is in a clamping state.

[0050] The reference numerals in the accompanying drawings are as follows:

[0051] 1000, scanning device; 100, slide fixing device; 200, base; 210, scanning channel; 220, scanning cavity; 300, stage assembly; 310, focusing stage; 320, stage; 400, slide; 500, scanning assembly;

[0052] 1. Mounting base; 11. Support surface; 12. Inlet and outlet; 13. Mounting hole; 14. Backlight source; 15. Avoidance hole;

[0053] 2. First clamp / movable clamp; 21. First clamping portion; 22. Mounting portion;

[0054] 3. Second clamping member; 31. Second clamping portion;

[0055] 4. Clamping space;

[0056] 5. Clamping switch assembly; 51. Guide member; 511. Guide surface; 5111. Opening and holding surface; 5112. Transition arc surface; 5113. Clamping and holding surface; 52. Switch member / cam; 53. Linear moving assembly; 531. Guide rail; 532. Slider; 54. Elastic buffer. DETAILED DESCRIPTION

[0057] Unless otherwise defined, all technical and scientific terms used herein have the same meanings as commonly understood by those skilled in the art to which this invention pertains; the terms used in this specification are for the purpose of describing specific embodiments only and are not intended to limit this invention; for example, terms such as “length,” “width,” “up,” “down,” “left,” “right,” “front,” “back,” “vertical,” “horizontal,” “top,” “bottom,” “inside,” and “outside” indicate directions or positions based on those shown in the accompanying drawings, which are for ease of description only and are not to be construed as limiting this technical solution.

[0058] The terms "including," "having," and any variations thereof in the specification and claims of this utility model and the accompanying drawings are intended to cover non-exclusive inclusions. The terms "first," "second," and the like in the specification and claims of this utility model and the accompanying drawings are used to distinguish between different items, not to describe a particular order. "Multiple" means two or more, unless otherwise expressly specified.

[0059] In the specification and claims of this utility model and the above-mentioned description of the drawings, when an element is referred to as being “fixed to”, “mounted on”, “disposed on” or “connected to” another element, it may be directly or indirectly located on the other element. For example, when an element is referred to as being “connected to” another element, it may be directly or indirectly connected to the other element.

[0060] Furthermore, references to "embodiments" herein mean that a particular feature, structure, or characteristic described in connection with the embodiments may be included in at least one embodiment of the present invention. The appearance of this phrase in various places in the specification does not necessarily refer to the same embodiment, nor does it constitute an independent or alternative embodiment that is mutually exclusive of other embodiments. It is understood, both explicitly and implicitly, by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0061] The embodiment of the present invention provides a glass slide fixing device 100, which is mainly used to automatically fix and install a glass slide 400. The glass slide fixing device 100 can be applied to, but not limited to, a scanning device 1000 of a pathology slide scanner.

[0062] like Figure 1 、 Figure 3 and Figure 5 As shown, the slide fixing device 100 includes a mounting base 1, a first clamp 2, a second clamp 3, and a clamping switch assembly 5. The mounting base 1 is provided with a support surface 11 for placing a slide 400. The first clamp 2 and the second clamp 3 are mounted relative to the mounting base 1, and the first clamp 2, the second clamp 3, and the support surface 11 together form a clamping space 4 for placing the slide 400. It is understood that the first clamp 2 can be used to clamp the slide 400 from one side (specifically, the left side), and the second clamp 3 can be used to clamp the slide 400 from the other side (specifically, the right side).

[0063] In the embodiment of the present utility model, as Figure 1 、 Figure 3 and Figure 5 As shown, the first clamp 2 is provided with at least one first clamping portion 21 on the side facing the clamping space 4, and correspondingly, the second clamp 3 is also provided with at least one second clamping portion 31 on the side facing the clamping space 4, wherein, in the length direction of the glass slide 400, the ratio between the length of the clamping area jointly formed by the first clamping portion 21 and the second clamping portion 31 and the length of the glass slide 400 is greater than or equal to 1 / 2, so as to ensure that the first clamp 2 and the second clamp 3 stably clamp the glass slide 400. On the other hand, the contact surface of the first clamp 2, the second clamp 3 and the glass slide 400 can be reduced through the local contact between the first clamp 21 and the second clamp 31 and the glass slide 400, thereby reducing the contact area and contact probability of the first clamp 2, the second clamp 3 and the glue, which is beneficial to reduce the breakage rate of the glass slide 400 and realize safe and stable transportation of the glass slide 400.

[0064] In which, under the action of the clamping switch assembly 5, the first clamp 2 and the second clamp 3 are relatively close to each other, so as to clamp different parts of the glass slide 400 in the clamping space 4 from opposite sides of the glass slide 400 through the first clamp 21 and the second clamp 31, or the first clamp 2 and the second clamp 3 are relatively far away from each other, so as to release the clamping of the glass slide 400 in the clamping space 4.

[0065] It is understandable that in the clamping space 4, when the glass slide 400 placed on the supporting surface 11 of the mounting base 1 needs to be clamped, the first clamp 2 and the second clamp 3 can be brought relatively close to each other to clamp the glass slide 400 together. Figure 1As shown, in the clamping state, the first clamping portion 21 and the second clamping portion 31 respectively contact opposite side walls of the glass slide 400, and all the first clamping portions 21 and second clamping portions 31 can be arranged in a triangular or quadrangular shape. The specific arrangement of the first clamping portions 21 and second clamping portions 31 can be determined based on the actual number of first clamping portions 21 and second clamping portions 31. Furthermore, the size of the clamping space 4 is adapted to the size of the glass slide 400.

[0066] Alternatively, when the glass slide 400 needs to be removed from the support surface 11 of the mounting base 1, the first clamp 2 and the second clamp 3 can be moved away from each other, so that the glass slide fixing device 100 is in an open state, thereby releasing the clamping of the glass slide 400 in the clamping space 4. Figure 5 As shown, in the open state, there is a gap between the first clamping portion 21 and / or the second clamping portion 31 and the glass slide 400 .

[0067] It is also understandable that when there is only one first clamp 21, at least two second clamps 31 need to be provided, or, when there is only one second clamp 31, at least two first clamps 21 need to be provided. In this way, when the first clamp 2 and the second clamp 3 respectively clamp the glass slide 400 from opposite sides of the glass slide 400 at the same time, the first clamp 21 and the second clamp 31 can be arranged in at least a triangle. On the one hand, this can further effectively ensure that the first clamp 2 and the second clamp 3 stably clamp the glass slide 400. On the other hand, when the glass slide fixing device 100 is in the clamping state, the first clamp 21 and the second clamp 31 are respectively in contact with different parts of the glass slide 400, thereby reducing the contact area with the glass slide 400 through local contact, which is conducive to further reducing the breakage rate of the glass slide 400.

[0068] In summary, compared with the prior art, the slide fixing device 100 has at least the following beneficial effects:

[0069] The glass slide fixing device 100 automatically controls the relative approach or distance between the first clamp 2 and the second clamp 3 through the action of the mechanical clamping switch component 5, which is beneficial to improving the efficiency of fixing and installing the glass slide 400 on the one hand, and reducing the energy consumption during the installation process of the glass slide 400 on the other hand; in addition, in the length direction of the glass slide 400, the ratio between the length of the clamping area jointly formed by the first clamping portion 21 of the first clamp 2 and the second clamping portion 31 of the second clamp 3 and the length of the glass slide 400 is greater than or equal to 1 / 2, which can effectively ensure that the first clamp 2 and the second clamp 3 stably clamp the glass slide 400 on the one hand, and on the other hand, the contact surface of the first clamp 2, the second clamp 3 and the glass slide 400 is reduced through the partial contact between the first clamp 21 and the second clamp 31 and the glass slide 400, thereby reducing the contact area and contact probability of the first clamp 2, the second clamp 3 and the glue, which is beneficial to reducing the breakage rate of the glass slide 400 and realizing safe and stable transportation of the glass slide 400.

[0070] In order to make the technical personnel in this field better understand the present invention, the following Figures 1 to 5 , clearly and completely describe the technical solutions in the embodiments of the present utility model.

[0071] In some embodiments of the present invention, each of the first clamps 21 and each of the second clamps 31 has at least one point-to-surface contact with the corresponding side surfaces of the glass slide 400, thereby minimizing the contact area between the first clamp 2, the second clamp 3 and the glass slide 400 and ensuring the safe transportation of the glass slide 400.

[0072] For example, at least one arc-shaped protrusion (not shown) is provided on the side of the first clamping portion 21 and the second clamping portion 31 facing the glass slide 400. Alternatively, the side of the first clamping portion 21 and the second clamping portion 31 facing the glass slide 400 is a spherical surface, and the spherical surface is tangent to the side surface of the glass slide 400. In this way, the first clamping portion 21 can achieve point-to-surface contact with one side surface of the glass slide 400 (specifically, the left side), and the second clamping portion 31 can achieve point-to-surface contact with one side surface of the glass slide 400 (specifically, the right side).

[0073] and / or, such as Figure 1 As shown, the mounting base 1 is provided with an inlet and outlet 12 for placing a glass slide 400 on the support surface 11. The inlet and outlet 12 communicates with the clamping space 4. The inlet and outlet of the mounting base 1 correspond to the first clamping portion 21 and / or the second clamping portion 31. Thus, the first clamping portion 21 and / or the second clamping portion 31 clamp the glass slide 400 at the inlet and outlet, thereby preventing the glass slide 400 placed on the support surface 11 from moving out of the clamping space 4.

[0074] And / or, the first clamping portion 21 and the second clamping portion 31 are both arranged in a line with a gap along the length direction of the glass slide 400 , and the first clamping portion 21 and the second clamping portion 31 are arranged opposite to each other.

[0075] For example, in this embodiment, Figure 1 、 Figure 3 and Figure 5 As shown, at the entrance and exit of the mounting base 1, the first clamp, the second clamp, the first clamp 21 and the second clamp 31 are opposite to each other, so that the left and right sides of the glass slide 400 located here can be clamped by the relative arrangement of the first clamp 21 and the second clamp 31, which is beneficial to improve the installation stability of the glass slide 400.

[0076] Also illustratively, the first clamp is provided with a plurality of first clamps 21, and all the first clamps 21 are arranged with a straight line gap. The second clamp is provided with a plurality of second clamps 31, and all the second clamps 31 are also arranged with a straight line gap. The first clamps 21 and the second clamps 31 are directly opposite to each other, so as to clamp the glass slide 400 on both sides of the same part of the glass slide 400, so as to improve the safety and stability of clamping the glass slide 400.

[0077] Optionally, specifically in the present embodiment, in order to simplify the structure of the glass slide fixing device 100 and further ensure the safety and stability of the clamping of the glass slide 400, three first clamps 21 and three second clamps 31 are provided, and the three first clamps 21 are respectively used to clamp the front end, middle part and corresponding parts of the entrance and exit of the glass slide 400; the three second clamps 31 are respectively used to clamp the front end, middle part and corresponding parts of the entrance and exit of the glass slide 400, so as to clamp the front, middle and rear parts of the glass slide 400 to ensure the clamping stability, and also to ensure that the contact surface between the first clamp 2 and the second clamp 3 and the glass slide 400 is as small as possible.

[0078] Exemplarily, the glass slide 400 has an insertion end (not shown, i.e., the front end mentioned above) and an identification end (not shown). The insertion end can be inserted into the clamping space 4 from the entrance and exit along the length direction of the glass slide 400, and the identification end is exposed in the clamping space 4. Among them, the first clamp 2 is provided with three first clamps 21, and the three first clamps 21 are respectively distributed on one side (specifically, the left side), the middle part, and one side (specifically, the left side) of the entrance and exit of the glass slide 400. The second clamp 3 is provided with three second clamps 31, and the three second clamps 31 are respectively distributed on the other side (specifically, the right side), the middle part, and the other side (specifically, the right side) of the entrance and exit of the glass slide 400. As Figure 1 As shown, when the glass slide fixing device 100 is in a clamping state, the three pairs of first clamping parts 21 and second clamping parts 31 arranged opposite to each other can clamp the glass slide 400 from the inlet and outlet, the middle part and both sides of the insertion end of the glass slide 400 respectively to ensure the overall clamping stability and safety of the glass slide 400.

[0079] In some embodiments, in order to realize the automatic clamping or releasing operation of the first clamp 2 and the second clamp 3 on the glass slide 400, at least one of the first clamp 2 and the second clamp 3 is a movable clamp. Figure 1 As shown, the clamping switch assembly 5 includes a guide member 51 and a switch member 52, with the switch member 52 being disposed on the movable clamp. The guide member 51 has a guide surface 511, which includes an opening and holding surface 5111 and a clamping and holding surface 5113. The opening and holding surfaces 5111 and 5113 are sequentially arranged along the feeding direction of the slide 400 (specifically, the front-to-back direction).

[0080] When the switch member 52 abuts against the open holding surface 5111, a gap exists between the movable clamp (e.g., the first clamp 2) and the glass slide 400 in the clamping space 4, thereby releasing the clamping of the glass slide 400. At this time, the glass slide fixing device 100 is in the open state (see FIG. Figure 5 Alternatively, when the switch member 52 contacts the clamping holding surface 5113, the first clamping portion 21 and the second clamping portion 31 clamp the glass slide 400 together. At this time, the glass slide fixing device 100 is in a clamping state (see FIG. Figure 1 ).

[0081] For example, in this embodiment, Figure 1 As shown, the first clamp 2 is a movable clamp, and the second clamp 3 is fixedly installed on the mounting base 1. In this way, the glass slide 400 can be conveniently clamped with the second clamp 3 as a reference, which is beneficial to improving the stability and accuracy of clamping the glass slide 400 and also helps to reduce the difficulty of the clamping operation.

[0082] In addition, the opening and holding surfaces 5111 and the clamping and holding surfaces 5113 are arranged in a front-to-rear manner along the direction in which the glass slide 400 is fed. Thus, when the glass slide fixture 100 is in its initial position and the switch member 52 abuts the opening and holding surfaces 5111 of the guide member 51, the glass slide 400 can be easily fed into the clamping space 4. After the glass slide 400 is placed on the support surface 11 of the mounting base 1, the mounting base 1 can be directly moved away from the inlet and outlet 12, thereby moving the glass slide 400, the first clamp member 2, the second clamp member 3, and the switch member 52 along with the mounting base 1. During this movement, the first clamp member 2 gradually moves toward the second clamp member 3, and the switch member 52 gradually moves to the position of the clamping and holding surfaces 5113. When the switch member 52 abuts the clamping and holding surfaces 5113, the first clamp member 2 and the second clamp member 3 can jointly clamp the glass slide 400, ensuring that the glass slide fixture 100 is always in a clamped state.

[0083] On the contrary, when the switch member 52 abuts against the clamping holding surface 5113 of the guide member 51 and the glass slide fixing device 100 is in a clamping state, the mounting base 1 can be moved toward the direction of the inlet and outlet 12 to drive the glass slide 400, the first clamp 2, the second clamp 3 and the switch member 52 to move together with the mounting base 1. During this transfer process, the first clamp 2 can gradually move away from the second clamp 3, and the switch member 52 can also gradually move to the position of the open holding surface 5111. When the switch member 52 abuts against the open holding surface 5111, there is a preset gap between the first clamping portion 21 of the first clamp 2 and the glass slide 400, and they are no longer in contact, thereby ensuring that the glass slide fixing device 100 is always in an open state.

[0084] In general, the slide fixing device 100 has a simple and reliable structure, low energy consumption, and a simple and safe clamping operation.

[0085] Of course, in other embodiments, both the first clamp 2 and the second clamp 3 can be movable clamps, or the second clamp 3 can be a movable clamp, and their working principles are roughly the same as above, which will not be repeated here.

[0086] In some embodiments, in order to enable the switch member 52 to smoothly transition between the opening holding surface 5111 and the clamping holding surface 5113 during the transfer process to ensure the smoothness of the clamping and opening actions, the guide surface 511 of the guide member 51 also includes a transition arc surface 5112, wherein the transition arc surface 5112 is located between the opening holding surface 5111 and the clamping holding surface 5113; the opposite ends of the transition arc surface 5112 are respectively tangent to the opening holding surface 5111 and the clamping holding surface 5113.

[0087] When the switch member 52 moves relative to the guide member 51 in the direction of feeding the glass slide 400 (specifically, the direction of movement from front to back) and the switch member 52 abuts the transition arc 5112, the movable clamp (e.g., the first clamp 1) gradually approaches the glass slide 400 in the clamping space 4 to finally clamp the glass slide 400. When the switch member 52 moves relative to the guide member 51 in the direction of retracting the glass slide 400 (specifically, the direction of movement from back to front) and the switch member 52 abuts the transition arc 5112, the clamping force of the movable clamp (e.g., the first clamp 1) on the glass slide 400 in the clamping space 4 gradually decreases, finally releasing the clamping force of the glass slide 400.

[0088] And / or, in some embodiments, to simplify the overall structure and reduce wear between the switch member 52 and the guide member 51, the switch member 52 is a cam. When the guide member 51 and the switch member 52 abut, the wheel surface of the cam abuts the guide surface 511. In other words, during relative motion, the guide member 51 and the switch member 52 are in surface contact, which helps improve the safety and stability of the clamping operation.

[0089] In some embodiments, as Figure 4 As shown, when the first clamp 2 is a movable clamp, the clamping switch assembly 5 also includes a linear moving assembly 53, wherein the first clamp 2 is slidably connected to the mounting base 1 through the linear moving assembly 53, so that the first clamp 2 can stably and reliably move relatively close to or away from the second clamp 3.

[0090] For example, the linear motion assembly 53 includes a guide rail 531 and a slider 532 in sliding connection. One of the mounting base 1 and the first clamp 2 is provided with the guide rail 531, and the other is provided with the slider 532. Figure 4As shown, the mounting base 1 is provided with an escape hole 15, and a guide rail 531 is provided at a position corresponding to the escape hole 15 along the width direction of the glass slide 400. Correspondingly, a mounting portion 22 is provided on the inner wall of the first clamp 2, and a slider 532 is provided on the mounting portion 22. The mounting portion 22 is mounted in the escape hole 15, and the slider 532 is slidably connected to the guide rail 531 within the escape hole 15. As a result, when the first clamp 2 moves along the guide rail 531 relative to the mounting base 1, the first clamp 2 can stably and smoothly move closer to or farther away from the second clamp 3.

[0091] and / or, in some embodiments, as Figure 1 and Figure 3 As shown, the clamping switch assembly 5 further includes an elastic buffer 54 , which is disposed between the mounting base 1 and the first clamp 2 and is used to provide a buffer force for the opening or clamping of the first clamp 2 .

[0092] For example, the elastic buffer 54 is disposed along the width of the glass slide 400, with one end of the elastic buffer 54 connected to the first clamp and the other end connected to the mounting base 1. When the first clamp 2 approaches the second clamp 3, the elastic buffer 54 provides a buffering force, gradually edging closer to the glass slide 400, thereby ensuring secure gripping of the glass slide 400. When the switch 52 disengages from the guide 51 and continues to move along the length of the glass slide 400 with the mounting base 1, the first clamp 2 can stably grip the glass slide 400 through the elastic buffer 54, preventing it from easily shifting due to vibrations of the mounting base 1, thereby ensuring secure gripping of the glass slide 400.

[0093] Based on the above-mentioned slide fixing device 100, as Figures 6 to 8 As shown, an embodiment of the present invention further provides a scanning device 1000, wherein the scanning device 1000 includes a stage assembly 300, a scanning assembly 500, and the aforementioned slide fixture 100. The stage assembly 300 is primarily used to carry a slide 400. The scanning assembly 500 is primarily used to scan a passing slide 400 to obtain a digital image of a tissue section on the slide 400. The mounting base 1 of the slide fixture 100 is disposed on the stage assembly 300.

[0094] In summary, compared with the prior art, the scanning device 1000 has at least the following beneficial effects: by adopting the above-mentioned glass slide fixing device 100, the scanning device 1000 can improve the efficiency of fixing and installing the glass slide 400, reduce overall energy consumption, and ensure safe and stable transportation of the glass slide 400.

[0095] In some embodiments, as Figures 6 to 8As shown, the scanning device 1000 further includes a base 200, wherein the base 200 is provided with a scanning channel 210. When the clamping switch assembly 5 of the slide fixing device 100 includes a guide member 51 and a switch member 52, the guide member 51 is provided on the base 200 near the entrance of the scanning channel 210 (see FIG. Figure 6 ); the guide surface 511 of the guide member 51 is located on the side away from the stage assembly 300.

[0096] For example, Figure 6 As shown, a scanning cavity 220 is formed in the base 200, and the scanning channel 210 is located in the scanning cavity 220. Figure 7 and Figure 8 As shown, the scanning assembly 500 is located above the stage assembly 300 in the scanning chamber 220. The slide fixing device 100 can move along the scanning channel 210 in the scanning chamber 220 together with the stage assembly 300. Driven by the stage assembly 300, the slide 400 clamped and fixed by the slide fixing device 100 can pass through the scanning assembly 500 for scanning by the scanning assembly 500 to obtain a digital slice image.

[0097] It should be noted that, when the slide fixture 100 moves along the scanning channel 210 together with the stage assembly 300, whether moving backward or forward, as long as the switch member 52 (specifically, a cam) of the slide fixture 100 does not abut against the guide member 51, the slide fixture 100 is always in a clamped state.

[0098] In addition, if Figure 8 As shown, as long as the switch member 52 of the slide fixture 100 abuts against the clamping holding surface 5113 of the guide member 51, the slide fixture 100 is always in a clamped state regardless of whether the stage assembly 300 drives the slide fixture 100 to move backward or forward. Figure 8 As shown, as long as the switch member 52 of the slide fixture 100 abuts against the open retaining surface 5111 of the guide member 51, the slide fixture 100 is always in the open state regardless of whether the stage assembly 300 drives the slide fixture 100 to move backward or forward.

[0099] It should also be noted that when the glass slide fixing device 100 moves along the scanning channel 210 together with the stage assembly 300, when the switch member 52 (specifically, a cam) of the glass slide fixing device 100 abuts against the transition arc surface 5112 of the guide member 51, when the stage assembly 300 moves backward, the first clamp 2 of the glass slide fixing device 100 can gradually move closer to the second clamp 3 until the first clamp 2 and the second clamp 3 jointly clamp the glass slide 400.

[0100] On the contrary, when the stage assembly 300 moves forward, the first clamp 2 of the glass slide fixing device 100 can gradually move away from the second clamp 3, so that there is a gap between the first clamping portion 21 of the first clamp 2 and the glass slide 400, and when it moves until the distance between the first clamping portion 21 and the glass slide 400 reaches a preset distance, the switch member 52 abuts against the open retaining surface 5111.

[0101] In some embodiments, as Figure 9 and Figure 10 As shown, the stage assembly 300 includes a focusing stage 310 and a stage 320 for placing a slide 400. A mounting base 1 is mounted on top of the focusing stage 310. The stage 320 is the mounting base 1 of the slide fixture 100. Combining the mounting base 1 of the slide fixture 100 with the stage 320 of the stage assembly 300 simplifies the overall structure of the scanning device 1000, reduces mechanical installation errors, and improves scanning performance.

[0102] and / or, in some embodiments, as Figure 3 As shown, in order to further improve the scanning effect, a mounting hole 13 is opened on the mounting base 1 (that is, the carrier 320) at a position corresponding to the support surface 11 of the mounting base 1, wherein the mounting hole 13 is communicated with the clamping space 4, and a backlight source 14 is built into the mounting hole 13.

[0103] For example, at the bottom of the supporting surface 11 of the mounting base 1, a mounting hole 13 is opened on the mounting base 1, and a backlight source 14 is built into the mounting hole 13. In this way, when the stage assembly 300 carries the glass slide 400 clamped by the glass slide fixing device 100 and moves in the scanning cavity 220 to pass through the scanning assembly 500 for scanning by the scanning assembly 500, the light source provided by the backlight source 14 located at the bottom of the glass slide 400 can ensure that when there is insufficient light in the scanning cavity 220, the scanning assembly 500 obtains a clear digitized slice image, which is conducive to improving the scanning effect.

[0104] Based on the above-mentioned glass slide fixing device 100 , an embodiment of the present invention further provides a pathology slide scanner, wherein the pathology slide scanner includes the above-mentioned glass slide fixing device 100 . Alternatively, the pathology slide scanner includes the above-mentioned scanning device 1000 .

[0105] In summary, compared with the prior art, the scanning device 1000 has at least the following beneficial effects: by adopting the above-mentioned glass slide fixing device 100 or scanning device 1000, the scanning device 1000 can improve the efficiency of fixing and installing the glass slide 400, reduce overall energy consumption, and transport the glass slide 400 safely and stably, which is conducive to improving the scanning effect.

[0106] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Those skilled in the art will readily appreciate that various modifications and variations of the present invention are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present invention are intended to be within the scope of the claims of the present invention.

Claims

1. A slide fixing device, characterized in that: The slide fixing device includes a mounting base, a first clamp, a second clamp, and a clamping switch assembly. The mounting base is provided with a support surface for placing the slide. The first clamp and the second clamp are mounted relative to the mounting base and together with the support surface form a clamping space for placing the slide. The first clamping member is provided with at least one first clamping portion on a side facing the clamping space, and the second clamping member is provided with at least one second clamping portion on a side facing the clamping space; in the length direction of the glass slide, the ratio of the length of the clamping area formed by the first clamping portion and the second clamping portion to the length of the glass slide is greater than or equal to 1 / 2; Under the action of the clamping switch assembly, the first clamp and the second clamp are relatively close to each other, so as to clamp different parts of the glass slide in the clamping space from opposite sides of the glass slide through the first clamp and the second clamp, or the first clamp and the second clamp are relatively far away from each other, so as to release the clamping of the glass slide in the clamping space.

2. The slide fixing device according to claim 1, characterized in that: Each of the first clamping parts and each of the second clamping parts is in contact with the corresponding side surface of the glass slide at least at one point; And / or, the mounting seat is provided with an inlet and outlet for placing the glass slide into the supporting surface, the inlet and outlet being in communication with the clamping space; the inlet and outlet of the mounting seat corresponds to the first clamping portion and / or the second clamping portion; And / or, the first clamping portion and the second clamping portion are both spaced apart in a line along the length direction of the glass slide, and the first clamping portion and the second clamping portion are arranged opposite to each other.

3. The slide fixing device according to claim 2, characterized in that: There are three first clamps and three second clamps, and the three first clamps are used to clamp the front end, middle part and corresponding parts of the entrance and exit of the glass slide respectively; the three second clamps are used to clamp the front end, middle part and corresponding parts of the entrance and exit of the glass slide respectively.

4. The slide fixing device according to any one of claims 1 to 3, characterized in that: At least one of the first clamp and the second clamp is a movable clamp; The clamping switch assembly includes: The guide member is provided with a guide surface; the guide surface includes an opening holding surface and a clamping holding surface; the opening holding surface and the clamping holding surface are arranged in sequence along the feeding direction of the glass slide; a switch member, disposed on the movable clamp; When the switch member contacts the opening holding surface, a gap exists between the movable clamp and the glass slide in the clamping space, thereby releasing the clamping of the glass slide; When the switch member abuts against the clamping and holding surface, the first clamping portion and the second clamping portion jointly clamp the glass slide.

5. The slide fixing device according to claim 4, characterized in that: The guide surface further includes a transition arc surface, which is located between the opening and holding surface and the clamping and holding surface; opposite ends of the transition arc surface are tangent to the opening and holding surface and the clamping and holding surface respectively; When the switch member moves relative to the guide member along the feeding direction of the glass slide and the switch member abuts against the transition arc surface, the movable clamp gradually approaches the glass slide in the clamping space to finally clamp the glass slide; When the switch member moves relative to the guide member along the retracting direction of the glass slide and the switch member abuts against the transition arc surface, the clamping force of the movable clamp on the glass slide in the clamping space gradually decreases to eventually release the clamping of the glass slide; And / or, the switch member is a cam, and when the guide member abuts against the switch member, the wheel surface of the cam abuts against the guide surface.

6. The slide fixing device according to claim 4, characterized in that: The first clamp is a movable clamp, and the second clamp is fixedly mounted on the mounting seat; The clamping switch assembly further includes a linear motion assembly, through which the first clamp is slidably connected to the mounting seat so as to be able to move closer to or farther away from the second clamp; And / or, the clamping switch assembly further includes an elastic buffer member, which is arranged between the mounting seat and the first clamping member and is used to provide a buffering force for the opening or clamping of the first clamping member.

7. A scanning device, characterized in that: The scanning device comprises: Stage assembly, used for carrying slides; A scanning component, configured to scan a passing glass slide to obtain a digital image of a tissue slice on the glass slide; and The glass slide fixing device according to any one of claims 1 to 6, wherein the mounting base of the glass slide fixing device is provided on the stage assembly.

8. The scanning device according to claim 7, characterized in that The scanning device further comprises: A base, provided with a scanning channel; When the clamping switch assembly of the slide fixing device includes a guide member and a switch member, the guide member is provided on the base near the entrance of the scanning channel; the guide surface of the guide member is located on the side away from the stage assembly.

9. The scanning device according to claim 7, wherein: The stage assembly includes a focusing stage and a stage for placing a glass slide, wherein the stage is the mounting seat; the mounting seat is mounted on the top of the focusing stage; And / or, a mounting hole is provided on the mounting base at a position corresponding to the support surface of the mounting base; the mounting hole is communicated with the clamping space and has a built-in backlight source.

10. A pathology slide scanner, characterized in that: The pathological slide scanner comprises the slide fixing device according to any one of claims 1 to 6; Alternatively, the pathological slice scanner includes the scanning device according to any one of claims 7 to 9.

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