Portable microplate reader for rapidly detecting hepatitis C antigen

Abstract

The utility model relates to a portable microplate reader for rapidly detecting hepatitis C antigen, which comprises a shell, a detection chamber, an elisa plate, a detection component and a controller, and is characterized in that a light path transmission path between a light projecting part and a light receiving part is guided through a light guide part, so that the relative mounting positions of the light projecting part and the light receiving part are not limited; the technical problems that a light projecting part and a light receiving part of a traditional microplate reader are oppositely arranged at the upper end and the lower end of a detection pool, the size of the light projecting part and the size of the light receiving part limit the size of the microplate reader, the thickness cannot be further reduced, and the microplate reader is inconvenient to carry are solved.

Description

Technical Field

[0001] The utility model relates to the field of medical devices, and more particularly to a portable enzyme marker for rapidly detecting hepatitis C antigens. Background Art

[0002] In the prior art, a microplate reader is a specialized instrument used to read and analyze the results of an enzyme-linked immunosorbent assay (ELISA). Its core function is a colorimeter, which uses colorimetry to analyze the content of an antigen or antibody. The ELISA reaction is carried out by an enzyme coupled to the antigen or antibody, catalyzing a chromogenic substrate.

[0003] The light projecting and light receiving parts of a conventional microplate reader are respectively arranged at the opening end and the bottom end of the detection cell. The volume of the light projecting and light receiving parts limits the size and thickness of the microplate reader, making it inconvenient to carry.

[0004] Therefore, how to provide a new portable microplate reader for rapid detection of hepatitis C antigen, which can unrestrict the relative positions of the light-emitting part and the light-receiving part through the light-guiding part and optimize the internal space of the microplate reader is an urgent problem to be solved by those skilled in the art. Utility Model Content

[0005] In view of this, the present invention provides a portable microplate reader for rapid detection of hepatitis C antigen, aiming to solve the technical problem that the light-emitting part and the light-receiving part of the traditional microplate reader are relatively arranged at the upper and lower ends of the detection pool, resulting in the volume and thickness of the microplate reader cannot be further reduced.

[0006] A portable microplate reader for rapid detection of hepatitis C antigen, comprising:

[0007] a housing having a first end surface and a second end surface arranged opposite to each other in a front-to-rear direction thereof;

[0008] a detection chamber, the detection chamber being firmly connected to the first end surface and having horizontally arranged detection channels along both sides of the housing;

[0009] An ELISA plate, the ELISA plate being slidably connected to the interior of the detection channel, and the upper surface of the ELISA plate being provided with a plurality of detection pools along its length;

[0010] A detection assembly, comprising a light projecting portion, a light guiding portion, and a light receiving portion; the interior of the detection channel has an observation channel area along the height direction of the housing; the light projecting portion is mounted within the housing; the light guiding portion comprises an inlet and an outlet; the inlet is mounted within the housing and arranged opposite to the output end of the light projecting portion; the outlet is mounted within the detection chamber and arranged opposite to the top of the observation channel area; the light receiving portion is mounted within the detection chamber and arranged opposite to the bottom of the observation channel area; the light emitted by the light projecting portion is refracted through the inlet and outlet to the detection pool and the light receiving portion to provide sufficient brightness for the recognition of hepatitis C antigens;

[0011] A controller is electrically connected to the light projecting unit and the light receiving unit.

[0012] Through the above technical solution, the utility model solves the technical problem that the light-emitting part and the light-receiving part of the traditional microplate reader are relatively arranged at the upper and lower ends of the detection pool, resulting in the volume of the microplate reader cannot be further reduced in thickness. By adding a light-guiding part between the light-emitting part and the light-receiving part, the light path is guided by the light-guiding part, so that the relative position of the light-emitting part and the light-receiving part is not restricted, and the internal space of the microplate reader can be optimized, which has the characteristics of compact internal space and flexible layout.

[0013] Preferably, the light projecting part is installed inside the housing and is located on the same side of the observation channel area as the light receiving part.

[0014] Preferably, the introduction member includes a refractive member and a bracket, one end of the bracket is fastened to the top surface inside the shell, and the other end has an inclined mounting surface, the refractive member is fastened to the mounting surface and is arranged opposite to the light-projecting part.

[0015] Preferably, the guide member includes a refractive member 2 and a bracket 2, one end of the bracket 2 is fastened to the top surface inside the detection chamber, and the other end thereof has an inclined mounting surface 2, the refractive member 2 and the mounting surface 2 are fastened and arranged opposite to the light receiving part, and the mounting surface 2 and the mounting surface 1 are arranged opposite to each other.

[0016] Preferably, it also includes a positioning part, which is installed inside the detection chamber and located above the detection channel. The upper surface of the ELISA plate is also provided with a positioning groove. The detection channel is provided with a positioning through-hole passing through its side wall surface corresponding to the positioning end of the positioning part. The positioning end of the positioning part can elastically shrink and leak out of the positioning through-hole to position the positioning groove.

[0017] Preferably, the positioning part includes a positioning mounting seat, a positioning column and a spring, the positioning mounting seat is cylindrical with one end blocked, the open end of the positioning mounting seat is fastened to the top of the detection chamber chamber, and the other end is provided with a positioning column guide hole along its axial direction; the positioning column is slidably connected to the positioning column guide hole, one end of the positioning column is located inside the positioning mounting seat and is fastened to a limiting ring along its circumferential direction, and the other end passes through the positioning column guide hole and leaks out of the positioning mounting seat and is a round head setting; the spring is arranged inside the positioning mounting seat, one end of which contacts the top of the detection chamber chamber, and the other end contacts the limiting ring.

[0018] Preferably, the positioning grooves and the detection pools are staggered along the length direction of the ELISA plate to prevent the positioning posts from limiting the detection pools.

[0019] Preferably, the ELISA plate has a light-transmitting portion at the bottom of the detection pool, and other areas are made of opaque material.

[0020] Preferably, it further comprises a control panel, which is arranged on the upper surface of the shell and is connected to the controller by electrical signals.

[0021] Preferably, it further comprises a battery, which is installed inside the housing to supply power to the controller, the control panel, the light projecting part and the light receiving part.

[0022] It can be seen from the above technical solution that, compared with the prior art, the present invention discloses a portable microplate reader for rapid detection of hepatitis C antigen, which has the following beneficial effects:

[0023] 1. The light-emitting and light-receiving parts are located on the same side of the detection channel, which can optimize the thickness of the microplate reader affected by the volume of the light-emitting and light-receiving parts;

[0024] 2. The positioning unit can limit the relative position of the detection pool and the observation channel area without human visual monitoring, thereby improving detection efficiency;

[0025] 3. The positioning column can be elastically contracted and exposed to the positioning hole, which can be used to position multiple detection cells on the ELISA plate;

[0026] 4. The positioning grooves and the detection pools are staggered along the length of the ELISA plate, which can prevent the positioning columns from limiting the detection pools when multiple detection pools of the ELISA plate are switched;

[0027] 5. The bottom of the detection pool is light-transmissive, and the other areas are made of opaque materials to maintain a darkroom environment during the detection process and avoid interference from the external environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1A three-dimensional schematic diagram of a portable microplate reader for rapid detection of hepatitis C antigen provided by the utility model;

[0029] Figure 2 A three-dimensional schematic diagram of the ELISA plate provided by the utility model;

[0030] Figure 3 A partial cross-sectional view of the detection chamber, positioning portion, light receiving portion and guide member provided by the present invention in assembled state;

[0031] Figure 4 A top view of a portable microplate reader for rapid detection of hepatitis C antigen provided by the present invention;

[0032] Figure 5 for Figure 4 AA section view;

[0033] Figure 6 for Figure 4 BB cross-sectional view;

[0034] Figure 7 for Figure 6 A local enlarged view of point D;

[0035] Figure 8 for Figure 5 A partial enlarged view of point C.

[0036] Among them: 1-shell; 2-detection chamber; 3-enzyme labeling plate; 5-positioning part; 6-control panel; 21-detection channel; 22-observation channel area; 23-positioning through hole; 31-detection pool; 32-positioning groove; 33-light-transmitting part; 41-light-receiving part; 42-light-projecting part; 43-light-guiding part; 51-positioning mounting seat; 52-positioning column; 53-spring; 431-introduction part; 432-extraction part; 521-limiting ring; 4311-refractive part one; 4312-bracket one; 4321-refractive part two; 4322-bracket two. DETAILED DESCRIPTION

[0037] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.

[0038] See attached Figure 1-8 , the embodiment of the utility model discloses a portable microplate reader for rapid detection of hepatitis C antigen, comprising: a housing 1, a detection chamber 2, an microplate plate 3, a detection component and a controller;

[0039] The housing 1 has a first end surface and a second end surface that are arranged opposite to each other along the front-to-rear direction thereof;

[0040] The detection chamber 2 is firmly connected to the first end surface, and a horizontally arranged detection channel 21 is opened along both sides of the housing 1;

[0041] The ELISA plate 3 is slidably connected to the inside of the detection channel 21, and a plurality of detection pools 31 are provided on the upper surface of the ELISA plate 3 along its length direction;

[0042] The detection assembly includes a light projecting portion 42, a light guiding portion 43, and a light receiving portion 41. The detection channel 21 has an observation channel area 22 along the height direction of the housing 1. The light projecting portion 42 is installed inside the housing 1. The light guiding portion 43 includes an inlet 431 and an outlet 432. The inlet 431 is installed inside the housing 1 and is arranged opposite to the output end of the light projecting portion 42. The outlet 432 is installed inside the detection chamber 2 and is arranged opposite to the top of the observation channel area 22. The light receiving portion 41 is installed inside the detection chamber 2 and is arranged opposite to the bottom of the observation channel area 22. The light emitted by the light projecting portion 42 is refracted through the inlet 431 and the outlet 432 to the detection pool 31 and the light receiving portion 41 to provide sufficient brightness for the recognition of hepatitis C antigens.

[0043] The controller is electrically connected to the light projecting unit 42 and the light receiving unit 41 .

[0044] In order to further optimize the above technical solution, the light projecting unit 42 is installed inside the housing 1 and is located on the same side of the observation channel area 22 as the light receiving unit 41 .

[0045] In order to further optimize the above technical solution, the introduction member 431 includes a refractive member 4311 and a bracket 4312, one end of the bracket 4312 is fastened to the top surface inside the shell 1, and the other end thereof has an inclined mounting surface 1, the refractive member 4311 is fastened to the mounting surface 1 and is arranged opposite to the projecting part 42.

[0046] In order to further optimize the above technical solution, the export member 432 includes a refractive member 2 4321 and a bracket 2 4322. One end of the bracket 2 4322 is fastened to the top surface inside the detection chamber 2, and the other end thereof has an inclined mounting surface 2. The mounting surface 2 of the refractive member 2 4321 is fastened and arranged opposite to the light receiving part 41, and the mounting surface 2 and the mounting surface 1 are arranged opposite to each other.

[0047] In order to further optimize the above technical solution, it also includes a positioning part 5, which is installed inside the detection chamber 2 and located above the detection channel 21. The upper surface of the ELISA plate 3 is also provided with a positioning groove 32, and the detection channel 21 corresponds to the positioning end of the positioning part 5 and is provided with a positioning through-hole 23 passing through its side wall. The positioning end of the positioning part 5 can elastically shrink and leak out of the positioning through-hole 23 to position the positioning groove 32.

[0048] In order to further optimize the above technical solution, the positioning part 5 includes a positioning mounting seat 51, a positioning column 52 and a spring 53. The positioning mounting seat 51 is a cylinder with one end blocked. The open end of the positioning mounting seat 51 is tightly connected to the top of the chamber of the detection chamber 2, and the other end is provided with a positioning column guide hole along its axial direction; the positioning column 52 is slidingly connected to the positioning column guide hole, one end of the positioning column 52 is located inside the positioning mounting seat 51 and is tightly connected to the limiting ring 521 along its circumferential direction, and the other end passes through the positioning column guide hole and leaks out of the positioning mounting seat 51 and is set with a round head; the spring 53 is arranged inside the positioning mounting seat 51, one end of which contacts the top of the chamber of the detection chamber 2, and the other end contacts the limiting ring 521.

[0049] In order to further optimize the above technical solution, the positioning grooves 32 and the detection pools 31 are staggered along the length direction of the ELISA plate 3 to prevent the positioning columns 52 from limiting the detection pools 31 .

[0050] Specifically, the detection pools 31 are switched by manually pushing the ELISA plate 3 , thereby eliminating the motion mechanism used by the traditional ELISA instrument to switch multiple detection pools 31 , further simplifying the structure of the ELISA instrument and making it more portable.

[0051] To further optimize the above technical solution, the ELISA plate 3 has a light-transmitting portion 33 at the bottom of the detection pool 31, and the rest of the area is made of opaque material. This avoids the influence of external ambient light while not affecting the detection of the light-receiving portion 41.

[0052] In order to further optimize the above technical solution, a control panel 6 is further included. The control panel 6 is arranged on the upper surface of the housing 1 and is electrically connected to the controller.

[0053] In order to further optimize the above technical solution, a battery is also included, which is installed inside the housing 1 to power the controller, the control panel 6, the light projecting unit 42 and the light receiving unit 41. As a result, it is more convenient to carry and use.

[0054] The specific principle and usage of a portable microplate reader for rapid detection of hepatitis C antigen provided in this embodiment are as follows:

[0055] 1. Turn on the portable microplate reader;

[0056] 2. Insert the ELISA plate 3 to be tested into the detection channel 21 with the open end of the detection reservoir 31 facing upwards and the detection reservoir 31 positioned in front of the positioning groove 32;

[0057] 3. A "click" sound is heard, indicating that the positioning post 52 and the positioning groove 32 are locked into place;

[0058] 4. The light emitted by the light-emitting unit 42 passes through the first refraction member 4311 and the second refraction member 4321 and is irradiated onto the substance to be detected at the bottom of the detection cell 31. The light-receiving unit 41 identifies the substance to be detected.

[0059] 5. After the detection of this detection pool is completed, manually push the ELISA plate 3 forward to detect the next detection pool 31.

[0060] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A portable microplate reader for rapid detection of hepatitis C antigen, characterized in that: include: A housing (1), the housing (1) having a first end surface and a second end surface arranged opposite to each other along a front-to-rear direction thereof; A detection chamber (2), the detection chamber (2) being firmly connected to the first end surface and having horizontally arranged detection channels (21) opened along both sides of the housing (1); An enzyme labeling plate (3), the enzyme labeling plate (3) being slidably connected to the inside of the detection channel (21), and a plurality of detection pools (31) being provided on the upper surface of the enzyme labeling plate (3) along its length direction; A detection component, the detection component comprising a light projecting portion (42), a light guiding portion (43) and a light receiving portion (41); an observation channel area (22) is provided inside the detection channel (21) along the height direction of the housing (1); the light projecting portion (42) is installed inside the housing (1); the light guiding portion (43) comprises an inlet member (431) and an outlet member (432); the inlet member (431) is installed inside the housing (1) and is arranged opposite to the output end of the light projecting portion (42); The guide member (432) is installed inside the detection chamber (2) and arranged opposite to the top end of the observation channel area (22), and the light receiving portion (41) is installed inside the detection chamber (2) and arranged opposite to the bottom end of the observation channel area (22); the light emitted by the light projecting portion (42) is refracted through the guide member (431) and the guide member (432) to the detection pool (31) and the light receiving portion (41) to provide sufficient brightness for the recognition of hepatitis C antigens; A controller is electrically connected to the light projecting unit (42) and the light receiving unit (41).

2. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 1, characterized in that: The light projecting portion (42) is installed inside the housing (1) and is located on the same side of the observation channel area (22) as the light receiving portion (41).

3. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 2, characterized in that: The introduction member (431) includes a refractive member (4311) and a bracket (4312), one end of the bracket (4312) is fixedly connected to the top surface inside the shell (1), and the other end thereof has an inclined mounting surface (4312), and the refractive member (4311) is fixedly connected to the mounting surface (4311) and arranged opposite to the light-projecting portion (42).

4. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 3, characterized in that: The guide member (432) includes a second refractive member (4321) and a second bracket (4322), one end of the second bracket (4322) is fastened to the top surface inside the detection chamber (2), and the other end thereof has an inclined mounting surface (2), the second refractive member (4321) and the second mounting surface are fastened and arranged opposite to the light receiving portion (41), and the second mounting surface and the first mounting surface are arranged opposite to each other.

5. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 1, characterized in that: The invention also includes a positioning portion (5), which is installed inside the detection chamber (2) and located above the detection channel (21). The upper surface of the ELISA plate (3) is also provided with a positioning groove (32). The detection channel (21) is provided with a positioning through hole (23) penetrating the side wall thereof corresponding to the positioning end of the positioning portion (5). The positioning end of the positioning portion (5) can be elastically contracted and exposed to the positioning through hole (23) to position the positioning groove (32).

6. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 5, characterized in that: The positioning portion (5) includes a positioning mounting seat (51), a positioning column (52) and a spring (53). The positioning mounting seat (51) is cylindrical with one end blocked. The open end of the positioning mounting seat (51) is tightly connected to the top of the chamber of the detection chamber (2), and the other end thereof is provided with a positioning column guide hole along its axial direction; the positioning column (52) is slidably connected to the positioning column guide hole, one end of the positioning column (52) is located inside the positioning mounting seat (51) and is tightly connected to the limiting ring (521) along its circumferential direction, and the other end thereof passes through the positioning column guide hole and leaks out of the positioning mounting seat (51) and is set with a round head; the spring (53) is arranged inside the positioning mounting seat (51), one end of which contacts the top of the chamber of the detection chamber (2), and the other end contacts the limiting ring (521).

7. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 6, characterized in that: The positioning grooves (32) and the detection pool (31) are arranged in a staggered manner along the length direction of the ELISA plate (3) to prevent the positioning column (52) from limiting the detection pool (31).

8. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 1, characterized in that: The ELISA plate (3) has a light-transmitting portion (33) at the bottom of the detection pool (31), and the other areas are made of opaque material.

9. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 1, characterized in that: It also includes a control panel (6), which is arranged on the upper surface of the housing (1) and is connected to the controller by electrical signals.

10. A portable microplate reader for rapid detection of hepatitis C antigen according to claim 1, characterized in that: It also includes a battery, which is installed inside the housing (1) to supply power to the controller, the control panel (6), the light projecting part (42) and the light receiving part (41).

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