Four-channel variable-pitch pipetting module

Abstract

The utility model relates to the technical field of experimental instruments, in particular to a four-channel variable-pitch pipetting module, which comprises a four-channel variable-pitch assembly, four groups of lifting assemblies and four groups of pipetting assemblies, the four-channel variable-pitch assembly is connected with the four groups of lifting assemblies, and the four groups of lifting assemblies are respectively connected with the four groups of pipetting assemblies. According to the four-channel variable-pitch pipetting module, through cooperation of the pitch changing assembly, the lifting assembly and the pipetting assembly, the four sets of pipetting heads can be driven to achieve lifting and pitch changing at the same time, meanwhile, the pipetting heads are of an adjustable structure, the positions of the pipetting heads can be flexibly adjusted, and therefore the movement range of the pipetting heads is greatly widened, and the application range of the four-channel variable-pitch pipetting module is widened.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental instruments, in particular to a four-channel variable-distance pipetting module. Background Art

[0002] Sampling and pipetting instruments are widely used in biochemical, molecular, and cellular biology experiments. Their function is to sample and transfer a certain volume of liquid. The pipetting mechanism is one of its core mechanisms, used to extract, transport, and transfer liquids between standard containers. Common containers include standard SBS plates (8-well, 96-well, and 384-well deep-well plates), reagent plates, and standard 1-20ml vacuum blood sample tubes.

[0003] Multi-channel variable-pitch pipetting modules can precisely control the spacing between pipetting heads, meeting high-throughput and well-pitch requirements. However, existing multi-channel variable-pitch pipetting modules are relatively complex in overall structure, especially the pipetting head. The four channels occupy a large volume, which reduces the variable-pitch range of each pipetting head. Furthermore, since the position of the pipetting heads is fixed and cannot be flexibly adjusted, their versatility is limited. Utility Model Content

[0004] In view of the deficiencies in the prior art, the utility model provides a four-channel variable-distance pipetting module which can improve the motion range of the pipetting head, has flexible adjustment, and has a wide range of applications.

[0005] The utility model is achieved through the following technical solutions:

[0006] A four-channel variable-distance pipetting module includes a four-channel variable-distance component, four sets of lifting components and four sets of pipetting components. The four-channel variable-distance component is connected to the four sets of lifting components, and the four sets of lifting components are respectively connected to the four sets of pipetting components:

[0007] The four-channel pitch-changing assembly includes a bracket, a pitch-changing motor, a first lifting guide rail, a horizontal guide rail, a pitch-changing plate and a sliding seat, the first lifting guide rail and the horizontal guide rail are fixed on the bracket, the first lifting guide rail is perpendicular to the horizontal, and the horizontal guide rail is parallel to the horizontal plane, the pitch-changing plate is slidably connected to the first lifting guide rail, the pitch-changing motor is fixed on the bracket and connected to the pitch-changing plate, four downward-inclined guide grooves are evenly provided on the pitch-changing plate, and the inclination angle of the guide grooves gradually decreases from the middle to the two ends, and there are four sliding seats, which are slidably connected to the horizontal guide rail, and each sliding seat is provided with a pulley, and each pulley is slidably connected to each guide groove, and the pitch-changing motor can drive the pitch-changing plate to move up and down along the first lifting guide rail, so that each sliding seat moves horizontally along the horizontal guide rail to realize the pitch-changing movement of each sliding seat;

[0008] The lifting assembly consists of four groups, including a housing, a lifting motor, a lifting support plate, and a second lifting guide rail. Each housing is fixed to each sliding seat respectively. The lifting motor is fixed to the top of the housing. The lifting support plate is arranged in the housing and connected to the lifting motor. The second lifting guide rail is fixed outside the housing and is perpendicular to the horizontal plane.

[0009] The pipetting assembly includes a shell, a pipetting motor, a pipetting drive and a pipetting head. The shell is slidably connected to the second lifting guide rail, the shell is fixed to the lifting support plate, the pipetting motor is fixed to the top of the shell, and the pipetting drive is arranged in the shell. The pipetting motor is connected to the pipetting head through the pipetting drive, and the pipetting motor can realize the suction or discharge of liquid by the pipetting head through the pipetting drive.

[0010] In order to avoid interference between the lifting and lowering of various components, the sliding seat includes an upper connecting part perpendicular to the horizontal plane, a transition part arranged at the bottom end of the upper connecting part and extending in the horizontal direction, and a lower connecting part arranged on the outside of the transition part and extending downward. The pulley is rotatably connected to the upper connecting part, and the outer shell is fixed to the lower connecting part.

[0011] In order to facilitate the lifting and lowering of the lifting support plate, a screw rod is provided in the shell. One end of the lifting support plate is threadedly connected to the screw rod, and the other end extends to the outside of the shell and is fixed to the shell.

[0012] In order to enable the positions of the pipetting heads to be flexibly adjusted so that they can be gathered together or separated, the pipetting heads are movably connected to the bottom end of the shell through an adjustable support plate, and the adjustable support plate is rotatably connected to the shell through a pin.

[0013] The beneficial effects of the present utility model are as follows: the four-channel variable-distance pipetting module can drive four groups of pipetting heads to simultaneously achieve lifting and changing distances through the cooperation of the variable-distance component, the lifting component and the pipetting component. At the same time, the pipetting heads adopt an adjustable structure, which can flexibly adjust their positions, thereby greatly improving the movement range of the pipetting heads and improving the applicability of the four-channel variable-distance pipetting module. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the three-dimensional structure of the four-channel variable-distance pipetting module of the present invention;

[0015] Figure 2 This is a schematic diagram of the three-dimensional structure of the four-channel variable pitch assembly of the present invention;

[0016] Figure 3 This is a schematic diagram of the three-dimensional structure of the lifting assembly of the utility model;

[0017] Figure 4 It is a schematic diagram of the three-dimensional structure of the pipetting component of the present utility model. DETAILED DESCRIPTION

[0018] The following is a detailed description of the preferred embodiments of the present invention in conjunction with the accompanying drawings, so that the advantages and features of the present invention can be more easily understood by those skilled in the art, thereby making a clearer and more precise definition of the scope of protection of the present invention. The directional terms mentioned in the present invention, such as "up", "down",

[0019] The terms "front", "back", "left", "right", "top", "bottom", etc. are merely directions in reference to the accompanying drawings. Therefore, the directional terms used are for explaining and understanding the present invention, and are not intended to limit the present invention.

[0020] like Figure 1 The four-channel variable-distance pipetting module shown includes a four-channel variable-distance component 1, four groups of lifting components 2 and four groups of pipetting components 3. The four-channel variable-distance component 1 is connected to the four groups of lifting components 2. The four-channel variable-distance component 1 can drive the four groups of lifting components 2 to achieve distance change. The four groups of lifting components 2 are respectively connected to the four groups of pipetting components 3. The lifting components 2 can drive the pipetting components 3 to achieve lifting.

[0021] Specifically, combined Figure 2 As shown, the four-channel pitch-changing assembly includes a bracket 103, a pitch-changing motor 101, a first lifting guide rail 104, a horizontal guide rail 105, a pitch-changing plate 102 and a sliding seat 106. The first lifting guide rail 104 and the horizontal guide rail 105 are fixed to the bracket 103. The first lifting guide rail 104 is located on both sides of the horizontal guide rail 105. The first lifting guide rail 104 is perpendicular to the horizontal plane, and the horizontal guide rail 105 is parallel to the horizontal plane. The pitch-changing plate 102 is slidably connected to the first lifting guide rail 104. The pitch-changing motor 101 is fixed to the top of the bracket 103 and connected to the pitch-changing plate 102. Four downward-inclined guide grooves 107 are evenly opened on the pitch-changing plate 102. The guide grooves 107 The inclination angle gradually decreases from the middle to the two ends. There are four sliding seats 106, which are slidably connected to the horizontal guide rail 105. The sliding seat 106 includes an upper connecting part perpendicular to the horizontal plane, a transition part arranged at the bottom end of the upper connecting part and extending in the horizontal direction, and a lower connecting part arranged on the outside of the transition part and extending downward. The pulley 108 is rotatably connected to the upper connecting part, and the lower connecting part is fixed to the outer shell of the lifting assembly. Each pulley 108 is slidably connected to each guide groove 107 respectively. The pitch variable motor 101 can drive the pitch variable plate 102 to move up and down along the first lifting guide rail 104, so that each sliding seat 106 moves horizontally along the horizontal guide rail 105, thereby realizing the pitch variable movement of each sliding seat 106.

[0022] Specifically, combined Figure 3As shown, the lifting components are four groups, including a shell 201, a lifting motor 202, a lifting support plate 204, and a second lifting guide rail 205. The rear side of each shell 201 is fixed to each sliding seat 106 respectively, and the lifting motor 202 is fixed to the top of the shell 201. A screw rod 203 is provided in the shell 201. One end of the lifting support plate 204 is threadedly connected to the screw rod 203, and the other end extends to the outside of the shell 201. The second lifting guide rail 205 is fixed to the outside of the shell 201. The second lifting guide rail 205 is perpendicular to the horizontal plane. The lifting motor 202 can drive the lifting support plate 204 to move up and down.

[0023] Specifically, combined Figure 4 As shown, the pipetting assembly includes a shell 301, a pipetting motor 302, a pipetting drive and a pipetting head 304. The shell 301 is slidably connected to the second lifting guide rail 205. The rear side of the shell 301 is fixed to the lifting support plate 204. The pipetting motor 302 is fixed to the top of the shell 301. The pipetting drive is arranged in the shell 301. The pipetting head 304 is movably connected to the bottom end of the shell 301 through an adjustable support plate 303. The adjustable support plate 303 is rotatably connected to the shell 301 through a pin. Before use, the distance between each pipetting head 304 can be adjusted by rotating the adjustable support plate 303. The pipetting motor 302 is connected to the inner cavity of the pipetting head 304 through the pipetting drive. The pipetting motor 302 can realize the suction or discharge of liquid by the pipetting head 304 through the pipetting drive.

[0024] During use, the variable pitch motor 101 drives the variable pitch plate 102 to descend along the first lifting guide rail 104, and then each pulley 108 rolls upward along each guide groove 107, so that each sliding seat 106 moves horizontally along the horizontal guide rail 105 and separates from each other, thereby realizing the variable pitch movement of each sliding seat 106; after completing the variable pitch action, each lifting motor 201 drives the screw rod 203 to rotate, driving the lifting support plate 204 and the pipetting assembly to gradually descend, so that the pipetting head 304 of the pipetting assembly is plugged into the consumables below; at this time, the pipetting motor 302 drives the internal pipetting drive (piston rod) to rise and fall, realizing the suction and discharge of liquid by the pipetting head 304.

[0025] In addition, in the description of the embodiments of the present invention, unless otherwise expressly specified or limited, the terms "installed," "connected," "connected," "set," and "provided with" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; and they can refer to internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on the specific circumstances.

[0026] The above-described embodiments merely represent several implementation methods of the present invention. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent. It should be noted that a person skilled in the art would be able to make numerous variations and improvements without departing from the concept of the present invention, and all such variations and improvements fall within the scope of protection of the present invention.

Claims

1. A four-channel variable-pitch pipetting module, comprising a four-channel variable-pitch assembly, four sets of lifting assemblies, and four sets of pipetting assemblies, wherein the four-channel variable-pitch assembly is connected to the four sets of lifting assemblies, and the four sets of lifting assemblies are respectively connected to the four sets of pipetting assemblies, characterized in that: The four-channel pitch-changing assembly includes a bracket, a pitch-changing motor, a first lifting guide rail, a horizontal guide rail, a pitch-changing plate and a sliding seat, the first lifting guide rail and the horizontal guide rail are fixed on the bracket, the first lifting guide rail is perpendicular to the horizontal, and the horizontal guide rail is parallel to the horizontal plane, the pitch-changing plate is slidably connected to the first lifting guide rail, the pitch-changing motor is fixed on the bracket and connected to the pitch-changing plate, four downward-inclined guide grooves are evenly provided on the pitch-changing plate, and the inclination angle of the guide grooves gradually decreases from the middle to the two ends, and there are four sliding seats, which are slidably connected to the horizontal guide rail, and each sliding seat is provided with a pulley, and each pulley is slidably connected to each guide groove, and the pitch-changing motor can drive the pitch-changing plate to move up and down along the first lifting guide rail, so that each sliding seat moves horizontally along the horizontal guide rail to realize the pitch-changing movement of each sliding seat; The lifting assembly consists of four groups, including a housing, a lifting motor, a lifting support plate, and a second lifting guide rail. Each housing is fixed to each sliding seat respectively. The lifting motor is fixed to the top of the housing. The lifting support plate is arranged in the housing and connected to the lifting motor. The second lifting guide rail is fixed outside the housing and is perpendicular to the horizontal plane. The pipetting assembly includes a shell, a pipetting motor, a pipetting drive and a pipetting head. The shell is slidably connected to the second lifting guide rail, the shell is fixed to the lifting support plate, the pipetting motor is fixed to the top of the shell, and the pipetting drive is arranged in the shell. The pipetting motor is connected to the pipetting head through the pipetting drive, and the pipetting motor can realize the suction or discharge of liquid by the pipetting head through the pipetting drive.

2. The four-channel variable-distance pipetting module according to claim 1, characterized in that: The sliding seat includes an upper connecting part perpendicular to the horizontal plane, a transition part arranged at the bottom end of the upper connecting part and extending in the horizontal direction, and a lower connecting part arranged outside the transition part and extending downward. The pulley is rotatably connected to the upper connecting part, and the shell is fixed to the lower connecting part.

3. The four-channel variable-distance pipetting module according to claim 1, characterized in that: A screw rod is provided in the shell, one end of the lifting support plate is threadedly connected to the screw rod, and the other end extends to the outside of the shell and is fixed to the shell.

4. The four-channel variable-distance pipetting module according to claim 1, characterized in that: The pipetting head is movably connected to the bottom end of the shell through an adjustable support plate, and the adjustable support plate is rotatably connected to the shell through a pin shaft.

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