Fixing ribbon for in-bag pipeline of disposable reaction bag

By designing the fixing ties on the cable tie cover and the base, the problem of the inner extension tube swinging freely in the reaction bag is solved, the inner extension tube is stably fixed, the shear force damage to the cells is reduced, and the cell culture effect is improved.

CN223422651UActive Publication Date: 2025-10-10JIANGSU BAITAI PHARM EQUIP TECH CO LTD
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Patent Information

Application Number
CN202421936509.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-12
Publication Date
2025-10-10
Estimated Expiration
2034-08-12

AI Technical Summary

Technical Problem

In the prior art, the inner extension tube swings randomly in the disposable reaction bag, causing shear damage to surrounding cells and affecting the quality of cell culture.

Method used

A fixed cable tie including a cable tie cover and a base is designed. The inner extension tube is fixed by cooperating with the cable tie strip and the limiting structure to prevent it from swinging at will.

Benefits of technology

The inner extension tube is effectively fixed, reducing shear force damage to cells and improving the quality of cell culture.

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Abstract

The utility model belongs to the technical field of biological reaction, and provides an in-bag pipeline fixing binding belt of a disposable reaction bag, which comprises a binding belt upper cover, a binding belt strip and a base, the ribbon upper cover comprises a pipeline placement concave part and a fastener, the pipeline placement concave part is arranged at the top of the fastener, and ribbon strip penetrating holes are formed in the two sides of the pipeline placement concave part respectively; table supports are arranged on the inner walls of the fasteners; a first-level spring bolt is arranged on one surface of the free end of the ribbon strip, a second-level spring bolt is arranged behind the first-level spring bolt, and the first-level spring bolt and the second-level spring bolt are located on the same surface. A limiting transverse strip is arranged on one surface of the ribbon strip fixing end; a limiting groove is formed in the other surface of the fixing end of the ribbon strip; the base comprises a welding disc and a base column head, the welding disc is provided with the base column head, and the base column head is provided with an annular protrusion. After the pipeline is assembled, the upper cover and the base of the cable tie are connected through the buckling positions, the pipeline is fixed, displacement of the pipeline is prevented, and shear force damage to peripheral cells caused by random swing of the inner extending pipe is reduced.
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Description

Technical Field

[0001] The utility model belongs to the technical field of biological reactions, in particular to a fixing tie for inner pipelines of a disposable reaction bag. Background Art

[0002] Disposable reaction bags are disposable components commonly used for cell culture and microbial reactions, and are now widely used in biopharmaceuticals and other fields. During the cell culture process, a series of operations such as inoculation and feeding are required. In order to reduce the cell shear force during the inoculation process or to meet the feeding needs below the liquid level, in the prior art, an inner extension tube is usually inserted into the cell culture bag. The inner extension tube is extended below the liquid level, usually at the bottom of the bag. However, the position of the inner extension tube in the bag is not fixed. It hangs freely or swings irregularly with the liquid as the blades rotate in the bag. This can easily cause greater shear force damage to the surrounding cells and affect the quality of cell culture. Therefore, a fixing device is needed to fix the inner extension tube.

[0003] The cable tie fixing device disclosed in the related reference CN214543365U has a cable tie strip fixed on a mounting head of a fixing assembly. Although the cable tie strip can bind the inner extension tube, the end face of the mounting head is flat and the mounting volume is large. Utility Model Content

[0004] The technical problem to be solved by the utility model is to provide a bag inner pipe fixing tie which can prevent the inner extension tube from swinging randomly in the bag, reduce the shear force damage of the inner extension tube to the surrounding cells, and install a disposable reaction bag with a smaller volume.

[0005] In order to solve the above technical problems, the utility model provides a cable tie for fixing the pipeline inside a disposable reaction bag, comprising a cable tie upper cover, a cable tie strip and a base;

[0006] The cable tie cover includes a pipeline placement recess and a fastener. The pipeline placement recess is set on the top of the fastener, and the cable tie strip passing hole I and the cable tie strip passing hole II are set on both sides of the pipeline placement recess; a platform is set on the inner wall of the fastener;

[0007] A first-level locking tongue is provided on one surface of the free end of the tie strip, a limiting horizontal bar is provided on one surface of the fixed end of the tie strip, and the limiting horizontal bar intersects the tie strip vertically; a limiting groove is provided on the other surface of the fixed end of the tie strip;

[0008] The base comprises a welding disk and a base column head. The welding disk is provided with the base column head, and the base column head is provided with an annular protrusion.

[0009] The cable tie strip and the cable tie cover of the present application form a pipeline binding assembly. After the pipeline is assembled, the cable tie cover and the base are connected by buckles to fix the pipeline, prevent the pipeline from shifting, and reduce the shear force damage to surrounding cells caused by the random swinging of the inner extension tube.

[0010] Preferably, the secondary lock tongue is arranged behind the primary lock tongue, and the primary lock tongue and the secondary lock tongue are located on the same surface.

[0011] Preferably, the limiting groove is matched with the hole inner step of the strap strip through hole I.

[0012] Preferably, the distance between the primary lock tongue and the secondary lock tongue is greater than the vertical dimension of the strap strip through hole II on the strap cover.

[0013] Preferably, the thickness of the limiting horizontal strip plus the thickness of the strap strip is greater than the strap strip through hole I.

[0014] Preferably, the limiting horizontal strip on the strap cover is matched with the limiting horizontal strip setting step.

[0015] Preferably, the fastener is a circular plastic plate, and an open groove is arranged on the circular plastic plate, and a separation end is arranged on the circular plastic plate, so that the fastener can be restored, and the column head of the base is facilitated to be installed.

[0016] Preferably, the table and the annular protrusion are connected in a snap-fit mode, and the base and the strap cover are connected in a snap-fit mode, so that the strap cover can rotate on the base, and the orientation of the pipeline is facilitated to be changed.

[0017] Preferably, a fastening guide strip is arranged on the surface of the strap strip fixed end, and the fastening guide strip is connected with the limiting horizontal strip. The hard interference of the fastening guide strip connected with the limiting horizontal strip through the fixed end can squeeze the limiting groove and the hole inner step together, so that the strap strip through hole tightly holds the strap strip, and the displacement of the inner extension pipe caused by the swing of the strap strip in the strap strip through hole is avoided.

[0018] Preferably, the welding disc is fixed to the inner surface of the disposable reaction belt.

[0019] Compared with the prior art, the utility model has the beneficial effects that:

[0020] 1. The strap strip and the strap cover form a pipeline binding assembly, after the pipeline is assembled, the strap cover and the base are connected through the buckle, the pipeline is fixed, the displacement of the pipeline is prevented, and the shear force damage to the surrounding cells caused by the random swing of the inner extension pipe is reduced.

[0021] 2. The utility model sets a separation end on the circular plastic plate, so that the fastener can be restored, and the column head of the base is facilitated to be installed.

[0022] 3. The hard interference of the fastening guide strip connected with the limiting horizontal strip through the fixed end can squeeze the limiting groove and the hole inner step together, so that the strap strip through hole tightly holds the strap strip, and the displacement of the inner extension pipe caused by the swing of the strap strip in the strap strip through hole is avoided. BRIEF DESCRIPTION OF DRAWINGS

[0023] Figure 1It is the exploded view of the utility model;

[0024] Figure 2 It is the schematic view of the utility model's cable strip;

[0025] Figure 3 It is the sectional view of the utility model;

[0026] Figure 4 It is the schematic view of the utility model's cable cover;

[0027] Figure 5 It is the schematic view of the utility model's assembly process;

[0028] Figure 6 It is the schematic view of the utility model's cable strip passing through hole II between the primary lock tongue and the secondary lock tongue.

[0029] Figure number: 1, cable cover, 2, cable strip, 3, base, 4, pipeline setting recess, 5, cable strip passing through hole I, 6, cable strip passing through hole II, 7, limiting horizontal bar setting step, 8, opening slot, 9, fastener, 10, primary lock tongue, 11, secondary lock tongue, 12, limiting groove, 13, limiting horizontal bar, 14, fastening guide strip, 15, table support, 16, welding disc, 17, base column head, 18, annular protrusion, 19, hole inner step. DETAILED DESCRIPTION

[0030] As Figure 1 A bag-in-pipe fixing cable of disposable reaction bag, including cable cover, 1, cable strip 2 and base 3.

[0031] The base 3 has a welding disc 16, a base column head 17, the base column head 17 is integrally arranged with the welding disc 16, and the annular protrusion 18 is arranged on the base column head 17. The table support 15 and the annular protrusion 18 are connected in a snap-fit manner, which can make the cable cover 1 rotate on the base 3, facilitating the change of the pipeline orientation. The welding disc 16 is used for welding with the disposable reaction bag, and it is noted that it is welded on the inner surface of the disposable reaction bag.

[0032] As Figure 2The cable tie strip 2 is shaped like a shoulder pole as a whole. A primary locking tongue 10 is provided near the free end, and a secondary locking tongue 11 is provided at the rear. The primary locking tongue 10 and the secondary locking tongue 11 are provided on the same surface and are spaced apart by a distance. The distance between them is greater than the vertical dimension of the hole Ⅱ6 through which the cable tie strip passes on the cable tie cover 1. A limiting horizontal bar 13 is provided on one side of the fixed end. The extension direction of the limiting horizontal bar 13 is perpendicular to the extension direction of the cable tie strip 2. The thickness of the limiting horizontal bar 13 plus the thickness of the cable tie strip 2 is greater than the hole Ⅰ5 through which the cable tie strip passes. The size of the limiting horizontal bar 13 matches the step 7 for placing the limiting horizontal bar on the cable tie cover 1. A limiting groove 12 is provided on the other side of the fixed end of the cable tie strip 2. The limiting groove 12 matches the step 19 in the hole Ⅰ5 through which the cable tie strip passes.

[0033] like Figure 3 The step 19 in the hole protrudes from the inner surface of the hole Ⅰ5 through which the tie strip passes. The support 15 is shaped like a corbel column. Its upper end is a step with a horizontal surface, and the lower end is smoothly connected to the inner surface of the hole. The matching of the limiting horizontal bar 13 and the limiting groove 12 with the hole Ⅰ5 through which the tie strip passes can prevent the tie strip 2 from continuing to move after passing through the hole Ⅰ5 until it falls off. A fastening guide bar 14 is provided on the surface of the fixed end of the tie strip 2. The fastening guide bar 14 is perpendicular to the limiting horizontal bar 13 and is connected to the limiting horizontal bar 13. Through the hard interference of the fastening guide bar 14 connected to the limiting horizontal bar 13 at the fixed end, the limiting groove 12 and the step 19 in the hole are squeezed together, so that the tie strip passes through the hole and tightly holds the tie strip 2, preventing the tie strip 2 from swinging in the hole through which the tie strip passes and causing the inner extension tube to shift.

[0034] like Figure 4 The cable tie cover 1 has a pipe placement recess 4 for placing the pipe to be fixed. On both sides of the pipe placement recess 4 are cable tie strip through holes Ⅰ5 and Ⅱ6; below the pipe placement recess 4 is a fastener 9, and the inner surface of the fastener 9 has a protruding support 15 shaped like a corbel column. The fastener 9 is a circular plastic sheet with one end separated and the other end fixed to each other. An open groove 8 is provided on the sheet, separating the separated ends into two circular arcs. The sheet can restore the divergent movement of the two plastic sheets at the separation point of the fastener 9, which is convenient for the installation of the base column head 17. When the fastener 9 is downward, the base column head 17 props up the fastener 9 until the support 15 moves down to below the annular protrusion 18 of the base column head 17.

[0035] The base 3 needs to be welded to the bag, and the base 3 is connected to the cable tie cover 1 through a buckle. The buckle connection method allows the cable tie cover 1 to rotate on the base 3, which is convenient for changing the orientation of the pipeline. Example 1:

[0036] like Figure 5With the side of the tie strip 2 with the locking tongue facing away from the tie cover 1, insert the free end of the tie strip through hole I5 and continue to move until the limiting groove 12 matches the step 19 in the hole. At this point, the tie strip 2 and the tie cover 1 form a pipe binding assembly.

[0037] The pipeline binding assembly can be assembled with the base 3 first; then the pipeline is placed in the pipeline placement recess 4; finally, the free end is inserted into the tie strip through the hole II6 and tightened to fix the pipeline, prevent the pipeline from shifting, and reduce the shear damage to the surrounding cells caused by the random swinging of the inner extension tube. Example 2:

[0038] With the side of the tie strip 2 with the locking tongue facing away from the tie cover 1, insert the free end of the tie strip through hole I5 and continue to move until the limiting groove 12 matches the step 19 in the hole. At this point, the tie strip 2 and the tie cover 1 form a pipe binding assembly.

[0039] like Figure 6 First, place the tubing in the tubing placement recess 4. Then, extend the free end of the tubing through hole II 6 until the tubing is positioned between the primary locking tongue 10 and the secondary locking tongue 11. At this point, the tubing tie assembly formed by the tubing tie 2 and the tie cover 1 can slide over the tubing. Next, assemble the tubing tie assembly with the base 3. Finally, tighten the tubing tie 2 and insert the secondary locking tongue 11 through hole II 6. This secures the tubing, prevents displacement, reduces shear damage to the cell culture caused by the inner extension tube, and improves cell culture quality.

[0040] At the same time, it can be understood that the position and length of the locking tongue, the width of the pipeline placement recess 4, and the positions of the primary locking tongue 10 and the secondary locking tongue 11 can be adjusted according to the size and number of the fixed pipelines.

[0041] Those skilled in the art will appreciate that the embodiments of the present invention described above and shown in the accompanying drawings are provided for illustrative purposes only and are not intended to limit the present invention. The objectives of the present invention have been fully and effectively achieved. The functional and structural principles of the present invention have been demonstrated and illustrated in the embodiments. Any variations or modifications may be made to the embodiments of the present invention without departing from the principles described.

Claims

1. A cable tie for fixing the inner pipe of a disposable reaction bag, characterized by: It includes a cable tie cover (1), a cable tie strip (2) and a base (3); The cable tie upper cover (1) comprises a pipeline placement recess (4) and a fastener (9), the pipeline placement recess (4) is provided on the top of the fastener (9), and cable tie strip passing hole I (5) and cable tie strip passing hole II (6) are provided on both sides of the pipeline placement recess (4); a support (15) is provided on the inner wall of the fastener (9); A first-level locking tongue (10) is provided on the surface of the free end of the tie strip (2); a limiting horizontal strip (13) is provided on one surface of the fixed end of the tie strip (2); the limiting horizontal strip (13) intersects the tie strip (2) vertically; and a limiting groove (12) is provided on the other surface of the fixed end of the tie strip (2); The base (3) comprises a welding disk (16) and a base column head (17); the welding disk (16) is provided with the base column head (17); and the base column head (17) is provided with an annular protrusion (18).

2. A cable tie for fixing the inner pipe of a disposable reaction bag according to claim 1, characterized in that: A secondary lock tongue (11) is provided behind the primary lock tongue (10), and the primary lock tongue (10) and the secondary lock tongue (11) are located on the same surface.

3. A cable tie for fixing the inner pipe of a disposable reaction bag according to claim 1, characterized in that: The limiting groove (12) matches the step (19) inside the hole through which the tie strip passes (5).

4. A cable tie for fixing the inner pipeline of a disposable reaction bag according to claim 2, characterized in that: The distance between the primary locking tongue (10) and the secondary locking tongue (11) is greater than the vertical dimension of the hole II (6) through which the tie strip passes on the tie upper cover (1).

5. A cable tie for fixing the inner pipeline of a disposable reaction bag according to claim 1, characterized in that: The thickness of the limiting horizontal strip (13) plus the thickness of the tie strip (2) is greater than the tie strip passing hole I (5).

6. A cable tie for fixing the inner pipeline of a disposable reaction bag according to claim 5, characterized in that: The limiting horizontal bar (13) matches the limiting horizontal bar placement step (7) on the cable tie upper cover (1).

7. A cable tie for fixing the inner pipeline of a disposable reaction bag according to claim 1, characterized in that: The fastener (9) is a circular plastic plate with an opening groove (8) provided on the plate.

8. The cable tie for fixing the inner pipeline of a disposable reaction bag according to claim 1, characterized in that: The support (15) and the annular protrusion (18) are snap-fitted and connected.

9. The cable tie for fixing the inner pipeline of a disposable reaction bag according to claim 1, characterized in that: A fastening guide bar (14) is provided on a surface of the fixed end of the tie strip (2), and the fastening guide bar (14) is connected to the limiting horizontal bar (13).

Citation Information

Patent Citations

  • Ribbon fixing device

    CN214543365U