Avian influenza hemagglutination inhibition test analyzer

By designing an avian influenza hemagglutination inhibition test analyzer that integrates a carrier rack, a rotating assembly, and a camera, the problem of low automation was solved, efficient and accurate sample testing and recording were achieved, and laboratory work efficiency was improved.

CN223461585UActive Publication Date: 2025-10-21NANJING YINGJIE BIOTECHNOLOGY CO LTD +1
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Patent Information

Application Number
CN202422585050.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-25
Publication Date
2025-10-21
Estimated Expiration
2034-10-25

AI Technical Summary

Technical Problem

The existing avian influenza hemagglutination inhibition test has a low degree of automation, cumbersome manual interpretation, inaccurate tilting time and angle leading to experimental deviation, and lacks recording equipment.

Method used

An avian influenza hemagglutination inhibition test analyzer was designed, which includes a sample carrier, a rotating component, a reciprocating component, a light source board and a camera. It can realize the automatic rotation, movement and image acquisition of samples, thereby improving the accuracy and efficiency of the experiment.

Benefits of technology

It improves the degree of automation of experiments, reduces human errors, saves time and labor costs, achieves efficient and accurate sample result recording, and meets the high efficiency needs of modern laboratories.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides an avian influenza hemagglutination inhibition test analyzer, which comprises a rack, and further comprises a carrier, a rotating assembly, a circulating assembly, a light source plate and a mounting plate, and a plurality of carrier holes are formed in the carrier and are used for placing hemagglutination plates to be detected. By means of the design, the device has more advantages in batch testing, and the working efficiency is improved. According to the design, the accuracy and the efficiency of an avian influenza hemagglutination inhibition test are improved, the time and the labor cost of a laboratory can be saved, the manual operation is reduced, the automation degree of the test is improved, the test efficiency is improved, the personal error is reduced, and a shot sample result can be recorded; and the work of scientific research and clinical detection is more efficient and quicker. Through reasonable structural design and intelligent function configuration, an efficient, accurate and reliable solution is provided for related research and clinical detection, and the requirements of modern laboratories for diversification and high efficiency of equipment are met.
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Description

TECHNICAL FIELD

[0001] The utility model relates to virus detection field, concretely is a kind of avian influenza hemagglutination inhibition test analyzer. BACKGROUND

[0002] Virus with hemagglutinin (HA) can agglutinate human or animal red blood cells, called hemagglutination phenomenon, and the hemagglutination phenomenon can be inhibited by the corresponding antibody, called hemagglutination inhibition test, a technique for determining antigen or antibody. And the final determination is based on whether agglutination phenomenon occurs, and when interpretation is needed, the reaction plate is inclined at 60°. Observe whether red blood cells have tear-drop-shaped flow. It is mainly applied to laboratory detection.

[0003] The current hemagglutination inhibition experiment is mainly applied to chicken farms and related industries. Usually, the number of poultry in chicken farms is large, and the sample is usually more than hundreds in a single experiment. However, a 96-well V-shaped plate can only do 8 samples, so the number of plates for a single experiment is usually dozens. For interpretation, it is a very tedious work. Interpretation is basically manual interpretation, with low automation degree, lack of recording equipment, with some subjective ideas, and insufficient tilting time or tilting angle, which can easily lead to experimental deviation. UTILITY MODEL CONTENT

[0004] The utility model aims to provide improved detection automation.

[0005] To achieve the above purpose, the utility model provides the following technical scheme: an avian influenza hemagglutination inhibition test analyzer, comprising a rack (1), further comprising:

[0006] A carrier rack (7);

[0007] A rotating assembly drives the carrier rack (7) to rotate to adjust the angle of the carrier rack (7). A reciprocating assembly drives the rotating assembly and the carrier rack (7) to move back and forth.

[0008] A light source plate (10) provides light for detection.

[0009] A mounting plate (11) has a camera (12) installed thereon.

[0010] Further, in the utility model, the carrier rack (7) has a plurality of carrier holes, and the carrier holes are used to place the hemagglutination plate to be detected.

[0011] Further, in the utility model, the circulating reciprocating assembly includes motor (2), annular toothed belt (3), slide rail (4), sliding block (5), the motor (2) and slide rail (4) are all installed in rack (1), the output shaft of motor (2) is driven annular toothed belt (3) rotation through gear, annular toothed belt (3) is driven sliding block (5) and slides on slide rail (4) along straight line.

[0012] Further, in the utility model, the rotating assembly includes rotating motor (6), the rotating motor (6) is fixedly installed on sliding block (5), the output shaft of rotating motor (6) is fixedly connected with carrier (7), and rotating motor (6) drives carrier (7) to rotate.

[0013] Further, in the utility model, the rack (1) is movably connected with the opening and closing door (13).

[0014] Further, in the utility model, the sliding block (5) is movably connected with rotating arm (8), the rack (1) is provided with side plate (9), and the long hole for the movement of rotating arm (8) is formed in the side plate (9).

[0015] Beneficial effects, the technical scheme of the application has the following technical effects:

[0016] The design of the utility model not only improves the accuracy and efficiency of the avian influenza hemagglutination inhibition test, but also saves the time and labor cost of the laboratory, reduces manual operation, improves the automation degree of the experiment, and further improves the experimental efficiency and reduces human error, can realize recording and shooting sample results, makes the work of scientific research and clinical detection more efficient and fast. Through reasonable structure design and intelligent function configuration, an efficient, accurate and reliable solution is provided for related research and clinical detection, which meets the diversification and high efficiency requirements of modern laboratory equipment.

[0017] It should be understood that all combinations of the foregoing concepts and additional concepts described in greater detail below can be seen as part of the utility model subject matter of the present disclosure, as long as such concepts are not mutually contradictory.

[0018] The foregoing and other aspects, embodiments and features of the present teachings can be more fully understood from the following description taken in conjunction with the accompanying drawings. Other aspects, features, and / or advantages of the utility model will be apparent from the description that follows and from the claims. BRIEF DESCRIPTION OF DRAWINGS

[0019] The drawings are not intended to be drawn to scale. In the drawings, each same or approximately same component shown in each of the drawings can be denoted by the same reference numeral. For the sake of clarity, not every component is labeled in each of the drawings. Embodiments of various aspects of the present application will now be described, by way of example only, with reference to the drawings in which:

[0020] Figure 1 is a structural schematic diagram of the present application.

[0021] Figure 2 is a structural schematic diagram of the present application.

[0022] Figure 3 is a structural schematic diagram of the present application (after the rotation of the object carrier).

[0023] Figure 4 is a structural schematic diagram of the present application.

[0024] In the drawings, the meanings of the reference numerals are as follows: 1, rack; 2, motor; 3, ring-shaped toothed belt; 4, slide rail; 5, slide block; 6, rotary motor; 7, object carrier; 8, rotary arm; 9, side plate; 10, light source plate; 11, mounting plate; 12, camera; 13, opening and closing door. DETAILED DESCRIPTION

[0025] In order to better understand the technical content of the present application, specific embodiments are described below in conjunction with the accompanying drawings. In the present disclosure, aspects of the present application are described with reference to the accompanying drawings, in which many embodiments of the description are shown. The embodiments of the present disclosure are not necessarily defined in all aspects including the present application. It should be understood that the various concepts and embodiments introduced above, as well as those described in more detail below, can be implemented in any one of many ways, since the concepts and embodiments disclosed by the present application are not limited to any implementation. In addition, some aspects of the present application can be used alone or in any appropriate combination with other aspects of the present application.

[0026] As Figures 1-4As shown, an avian influenza hemagglutination inhibition test analyzer includes a rack 1, and further includes: a carrier rack 7, a rotating assembly, a reciprocating assembly, a light source plate 10 and a mounting plate 11, the carrier rack 7 has a plurality of carrier holes for placing the hemagglutination plate to be detected, the rotating assembly drives the carrier rack 7 to rotate to adjust the angle of the carrier rack 7, and the reciprocating assembly drives the rotating assembly and the carrier rack 7 to move back and forth; the light source plate 10 provides light for detection; and the mounting plate is provided with a camera 12. The flexible sample placement function is achieved, the carrier rack 7 is provided with a plurality of carrier holes, and a plurality of hemagglutination plates to be detected can be placed at the same time. The design makes the device more advantageous when performing batch testing, and improves the work efficiency. The device is provided with the light source plate 10 and the mounting plate 11 provided with the camera 12, the combination of light irradiation and image acquisition can record the sample results. The design of the rack 1 considers the stability and safety of the device, and the opening and closing door 13 is arranged, so that the user can conveniently operate and maintain.

[0027] The instrument integrates the carrier rack 7, the rotating assembly, the reciprocating assembly, the light source plate 10 and the camera 13 and a plurality of functional modules, and can effectively complete each link of the hemagglutination inhibition test, including sample placement, detection and image acquisition. The integrated design improves the test efficiency and accuracy.

[0028] The reciprocating assembly includes a motor 2, an annular toothed belt 3, a sliding rail 4 and a sliding block 5, the motor 2 and the sliding rail 4 are both mounted on the rack 1, the output shaft of the motor 2 drives the annular toothed belt 3 to rotate through a gear, and the annular toothed belt 3 drives the sliding block 5 to slide linearly on the sliding rail 4 through a connecting rod. The rotating assembly includes a rotating motor 6, the rotating motor 6 is fixedly installed on the sliding block 5, the output shaft of the rotating motor 6 is fixedly connected with the carrier rack 7, and the rotating motor 6 drives the carrier rack 7 to rotate. The rotating assembly can flexibly adjust the angle of the carrier rack to adapt to different experimental requirements. Through rotation, the instrument can ensure the best irradiation angle of the light source and the sample, thereby improving the light transmittance and the definition of the image, and facilitating subsequent analysis. The reciprocating assembly enables the carrier rack to move back and forth, so that multiple samples can be quickly processed. The design reduces manual operation, improves the automation degree of the experiment, and further improves the experimental efficiency and reduces human errors.

[0029] The rack 1 is movably connected with an opening and closing door 13, the design of the rack considers the stability and safety of the device, and the opening and closing door is arranged, so that the user can conveniently operate and maintain. The reasonable structure design makes the use of the device more humanized.

[0030] In the utility model, the rotating arm 8 is movably connected on the sliding block 5, the rack 1 is provided with a side plate 9, and a long hole is formed in the side plate 9 for the rotation of the rotating arm 8. The sliding block 5 can be more stably moved.

[0031] In use, 6 experimental blood coagulation plates that have been prepared are used, the equipment is started, the opening and closing door 13 is opened to open the cabinet, the blood coagulation plates are placed on the extended loading rack 7 in turn, the opening and closing door 13 is closed, the plate position loading rack 7 is automatically retracted into the equipment and automatically inclined downward by 60°, the experiment reaches the specified time, the corresponding camera 13 is identified and recorded, and the experiment is completed, and 6 blood coagulation sample plates can be recorded at the same time.

[0032] The standard parts used in the present application can be purchased from the market, and can be ordered according to the description and drawings, the specific connection mode of each part adopts the conventional means such as bolt, rivet and welding in the prior art, the mechanical, part and equipment adopt the conventional type in the prior art, the control mode is automatically controlled through the controller, the control circuit of the controller can be realized through simple programming by the person skilled in the art, and belongs to the common knowledge in the art, and the present application is mainly used to protect the mechanical device, so the control mode and circuit connection will not be explained in detail.

[0033] Although the present application has been disclosed with the preferred embodiments, it is not intended to limit the present application. Those skilled in the art can make various modifications and decorations without departing from the spirit and scope of the present application. Therefore, the protection scope of the present application is defined by the claims.

Claims

1. An avian influenza hemagglutination inhibition test analyzer comprising a frame (1), characterized in that: Also include: A carrier (7); Rotary assembly, which drives the carrier (7) to rotate to adjust the angle of the carrier (7) reciprocating assembly, which drives the rotary assembly and the carrier (7) back and forth movement; Light source board (10), which provides light for detection; Mounting plate (11), which is provided with a camera (12).

2. The avian influenza hemagglutination inhibition test analyzer according to claim 1, characterized in that: The carrier (7) has a plurality of carrier holes for placing the blood clotting plate to be detected.

3. The avian influenza hemagglutination inhibition test analyzer according to claim 1, wherein: The reciprocating assembly includes a motor (2), a ring gear (3), a slide rail (4), and a sliding block (5). The motor (2) and the slide rail (4) are both mounted on the rack (1). The output shaft of the motor (2) drives the ring gear (3) to rotate through the gear. The ring gear (3) drives the sliding block (5) to slide linearly on the slide rail (4) through a connecting rod.

4. The avian influenza hemagglutination inhibition test analyzer according to claim 3, wherein: The rotary assembly includes a rotary motor (6) fixedly installed on the sliding block (5). The output shaft of the rotary motor (6) is fixedly connected with the carrier (7). The rotary motor (6) drives the carrier (7) to rotate.

5. The avian influenza hemagglutination inhibition test analyzer according to claim 1, wherein: The rack (1) is movably connected with an opening and closing door (13).

6. The avian influenza hemagglutination inhibition test analyzer according to claim 3, wherein: The sliding block (5) is movably connected with a rotary arm (8). The rack (1) is provided with a side plate (9). The side plate (9) is provided with a long hole for the rotary arm (8) to move.