Rat asthma model test box

Abstract

The utility model relates to the technical field of animal experiments, and discloses a rat asthma model test box which comprises a test box body and an atomizer arranged outside the test box body, and the output end of the atomizer is connected with a first test cavity and a second test cavity which are formed in the test box body through a connecting assembly. Box doors are installed at the opening ends of the first test cavity and the second test cavity, and a vibration assembly is installed in the second test cavity. A first test cavity and a second test cavity are formed in the test box, a vibration assembly vibration plate is arranged in the second test cavity, and two rats can be put into the first test cavity and the second test cavity respectively, so that one of the rats can be tested in the first test cavity in a normal respiratory rate state; and through cooperation of the vibration assembly and the vibration plate, another rat can be tested in the second test cavity in a state of relatively high respiratory rate, so that the rats in two different states can be observed and compared.

Description

Technical Field

[0001] This utility model relates to the field of animal experimental technology, specifically a rat asthma model test chamber. Background Technology

[0002] Risk factors for asthma include both host factors and environmental factors. Genetic factors can be seen in many patients. For example, most patients have a family history of asthma, recurrent cough and wheezing, or other allergic diseases. Most asthma patients have an allergic constitution and may also have allergic rhinitis and atopic dermatitis. To understand the symptoms and treatment of asthma, it is necessary to use mice in the laboratory for verification. This requires glass boxes and drugs to induce asthma in mice.

[0003] When conducting asthma tests on rats, the tests are usually performed on rats in different states, such as when the rats' respiratory rate is normal and when the rats' respiratory rate is high. However, the current test chambers are relatively simple in function and can usually only be used to test rats with a normal respiratory rate, and cannot be used to conduct asthma tests on rats in different states.

[0004] Therefore, we propose a rat asthma model test chamber to address the problems mentioned above. Utility Model Content

[0005] The purpose of this invention is to solve the problems mentioned above.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a rat asthma model test chamber, comprising a test chamber and a nebulizer disposed outside the test chamber. The output end of the nebulizer is connected to a first test chamber and a second test chamber opened on the test chamber via a connecting component. Both the opening ends of the first test chamber and the second test chamber are equipped with a door. A vibration component is installed inside the second test chamber, and a vibration plate that works in conjunction with the vibration component is also installed inside the second test chamber.

[0007] Furthermore: the vibration assembly includes a motor installed on the bottom wall of the second test chamber, and the motor is located below the vibration plate. The output shaft of the motor is fixed to the rotating disk. Several "triangular" protrusions are fixed at equal intervals along the circumferential direction on the top of the rotating disk. A vibration rod is fixed to the bottom of the vibration plate, and a striking ball that cooperates with several protrusions is fixed to the bottom of the vibration rod.

[0008] Furthermore, several springs are installed at the corner of the bottom of the vibrating plate, and the springs are fixed to the inner bottom wall of the second test chamber.

[0009] Furthermore, observation windows are installed on the sides and doors of the test chamber.

[0010] Furthermore, a timer is also installed on the top of the test chamber.

[0011] Furthermore: the connection assembly includes an atomizing tube installed at the output end of the atomizer, a T-connector installed at the end of the atomizing tube away from the atomizer, and two connecting tubes installed on the T-connector, the two connecting tubes respectively communicating with the interior of the first test chamber and the second test chamber.

[0012] The beneficial effects of this utility model are:

[0013] This invention features a test chamber with a first test chamber and a second test chamber inside, and a vibration assembly / vibration plate inside the second test chamber. Two rats can be placed into the first and second test chambers respectively, allowing one rat to be tested in the first test chamber with a normal respiratory rate. Through the cooperation of the vibration assembly and the vibration plate, the other rat can be tested in the second test chamber with a higher respiratory rate. This allows for observation and comparison of rats in two different states, improving the effectiveness of the test chamber. Attached Figure Description

[0014] Figure 1 This is a three-dimensional structural schematic diagram of the present invention;

[0015] Figure 2 This is a three-dimensional structural diagram of the test chamber in this utility model;

[0016] Figure 3 This is a cross-sectional structural diagram of the present invention;

[0017] Figure 4 This is a three-dimensional structural diagram of the vibration component in this utility model.

[0018] The names corresponding to each mark in the diagram:

[0019] 1. Test chamber; 2. Atomizer; 3. Connecting assembly; 31. Atomizing tube; 32. T-connector; 33. Connecting pipe; 4. First test chamber; 5. Second test chamber; 6. Chamber door; 7. Vibration assembly; 71. Motor; 72. Rotating disk; 73. Protrusion; 74. Vibration rod; 75. Striking ball; 8. Vibration plate; 9. Spring; 10. Observation window; 11. Timer. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model are within the protection scope of the present utility model.

[0021] Embodiments of this utility model:

[0022] A rat asthma model test chamber includes a test chamber 1 and a nebulizer 2 located outside the test chamber 1. The nebulizer 2 and the test chamber 1 are connected by a connecting component 3. Through the cooperation of the nebulizer 2 and the connecting component 3, a drug solution can be released into the test chamber 1 to conduct an asthma test on the rats. A timer 11 is also installed on the top of the test chamber 1 to facilitate the observation of the rat test time. An observation window 10 is installed on the side of the test chamber 1 to observe the condition of the rats.

[0023] Specifically: The test chamber 1 has a first test chamber 4 and a second test chamber 5. The first test chamber 4 allows the rats to be tested under normal respiratory rate conditions. The second test chamber 5 is equipped with a vibration component 7 and a vibration plate 8. The vibration component 7 is located below the vibration plate 8. The vibration component 7 can frequently tap the vibration plate 8, causing it to vibrate. This startles the rats in the second test chamber 5, causing them to breathe faster and thus accelerate the absorption of drugs from the air. This allows for asthma testing on two rats with different respiratory states. For easy comparison, springs 9 are fixed at the corners of the bottom of the vibration plate 8. Multiple springs 9 are fixed to the inner bottom wall of the same second test chamber 5, providing support for the vibration plate 8. Both the first test chamber 4 and the second test chamber 5 are equipped with doors 6, which close the first test chamber 4 and the second test chamber 5. Observation windows 10 are also installed on the doors 6, allowing for observation of the rats' condition from multiple angles.

[0024] More specifically: the vibration assembly 7 includes a motor 71 installed on the bottom wall of the second test chamber 5. The output end of the motor 71 is fixed with a rotating disk 72, and the top of the rotating disk 72 is fixed with several protrusions 73 at equal intervals along the circumferential direction. The protrusions 73 are in the shape of "right triangles". The bottom of the vibration plate 8 is fixed with a vibration rod 74, and the bottom end of the vibration rod 74 is fixed with a striking ball 75 that works with the protrusions 73. When the motor 71 drives the multiple protrusions 73 to rotate at high speed through the rotating disk 72, it can frequently strike the striking ball 75. The striking ball 75 can drive the vibration plate 8 to vibrate through the vibration rod 74.

[0025] Specifically: the connecting component 3 includes an atomizing tube 31 installed at the output end of the atomizer 2. A three-way connector 32 is installed at the end of the atomizing tube 31 away from the atomizer 2, and two connecting tubes 33 are installed on the three-way connector 32. The two connecting tubes 33 are respectively connected to the interior of the first test chamber 4 and the second test chamber 5. The drug atomized by the atomizer 2 can enter the interior of the atomizing tube 31, and the atomizing tube 31 can enter the interior of the connecting tubes 33 through the three-way connector 32, so that the drug in the two connecting tubes 33 can enter the interior of the first test chamber 4 and the second test chamber 5 respectively and be used to test rats.

[0026] Working principle

[0027] In the asthma test on rats, two rats are placed in the first test chamber 4 and the second test chamber 5 respectively. The nebulizer 2 and motor 71 are turned on simultaneously. The atomized medication from the nebulizer 2 enters the nebulization tube 31, and then flows through the three-way connector 32 into the connecting tubes 33. The medication in the two connecting tubes 33 then enters the first test chamber 4 and the second test chamber 5 respectively. The rat in the first test chamber 4 has a normal respiratory rate and inhales the medication from the air. The output shaft of the motor 71 drives several protrusions 73 to rotate at high speed via a rotating disk 72. This causes the protrusions 73 to frequently strike a striking ball 75, which in turn vibrates a vibrating plate 8 via a vibrating rod 74. This startles the rat in the second test chamber 5, increasing its respiratory rate and allowing it to inhale the medication from the air more quickly. This allows for observation and comparison of rats in different states, improving the effectiveness of the test chamber.

Claims

1. A rat asthma model test chamber, comprising a test chamber (1) and a nebulizer (2) disposed outside the test chamber (1), characterized in that: The output end of the atomizer (2) is connected to the first test chamber (4) and the second test chamber (5) opened on the test chamber (1) through the connecting component (3). The opening ends of the first test chamber (4) and the second test chamber (5) are both equipped with a door (6). The second test chamber (5) is equipped with a vibration component (7) and a vibration plate (8), and the vibration component (7) is located at the lower part of the vibration plate (8).

2. The rat asthma model test chamber according to claim 1, characterized in that: The vibration assembly (7) includes a motor (71) installed on the bottom wall of the second test chamber (5), and the motor (71) is located at the lower part of the vibration plate (8). The output shaft of the motor (71) is fixed to a rotating disk (72). Several triangular protrusions (73) are fixed at equal intervals along the circumferential direction on the top of the rotating disk (72). A vibration rod (74) is fixed to the bottom of the vibration plate (8), and a striking ball (75) that cooperates with several protrusions (73) is fixed to the bottom of the vibration rod (74).

3. The rat asthma model test chamber according to claim 1, characterized in that; Several springs (9) are installed at the corner of the bottom of the vibration plate (8), and the springs (9) are fixed to the inner bottom wall of the second test chamber (5).

4. The rat asthma model test chamber according to claim 1, characterized in that: The test chamber (1) is equipped with observation windows (10) on its side and on its door (6).

5. The rat asthma model test chamber according to claim 1, characterized in that: A timer (11) is also installed on the top of the test chamber (1).

6. The rat asthma model test chamber according to claim 1, characterized in that: The connecting assembly (3) includes an atomizing tube (31) installed at the output end of the atomizer (2). A three-way connector (32) is installed at the end of the atomizing tube (31) away from the atomizer (2), and two connecting tubes (33) are installed on the three-way connector (32). The two connecting tubes (33) are respectively connected to the interior of the first test chamber (4) and the second test chamber (5).

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