Incubation and uniform mixing equipment for removing erythrocyte agglutination
By combining a constant-temperature electric heating incubation tube with a rotating mixing disc, the problems of large water bath volume, slow heating, inaccurate temperature, and uneven mixing are solved, achieving rapid and accurate temperature control and uniform mixing of blood cells, thus improving the accuracy of test results.
Patent Information
- Application Number
- CN202422901720.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-27
- Publication Date
- 2025-11-07
- Estimated Expiration
- 2034-11-27
AI Technical Summary
In existing technologies, water baths are large in size, have slow heating speeds, inaccurate temperature control, are prone to bacterial growth, and cannot evenly mix blood cells, leading to inaccurate test results.
A constant-temperature electric heating incubation tube is used in conjunction with a rotating mixing disc. The disc is kept at 37±1°C by electric heating and rotates and is inverted in a cycle. The device is automatically controlled to stop and resume operation by a distance sensor to ensure that the blood cells are mixed evenly.
It achieves rapid and accurate temperature control, reduces equipment size and energy consumption, prevents bacterial growth, and improves the homogeneity of blood cell mixing and the accuracy of test results.
Smart Images

Figure CN223526090U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to medical instrument technical field, concretely relates to an incubation and mixing equipment for removing red blood cell agglutination. BACKGROUND
[0002] When working, the hospital blood sample examination department needs to first adopt a test tube to collect patient blood sample specimens, then carries out examination and analysis to the blood cells in the test tube, thereby obtaining results. But in the actual examination and analysis process, red blood cell agglutination specimens are often encountered, at this time, if the red blood cell agglutination is not removed and direct examination is carried out, the red blood cell count result will be seriously affected, thereby leading to inaccurate examination results.
[0003] At present, when the examination personnel encounter such situations, the conventional water bath box is usually adopted to incubate such specimens at 37 DEG C, after the agglutination phenomenon is disaggregated, machine examination is carried out. But careful analysis finds that the method has the following technical problems:
[0004] 1, the conventional water bath box is large in size, and also large in floor area, not only needs to add water for water bath at any time, but also needs long-term heating to keep the water bath box constant temperature at 37 DEG C ± 1 DEG C, and has the technical problems of large space occupation, inconvenient use and more energy consumption.
[0005] 2, the heating speed of the water bath box is slow each time, and the temperature is not easy to accurately control at constant temperature 37 DEG C ± 1 DEG C. In addition, the temperature of the water bath box is controlled at 37 DEG C ± 1 DEG C, which does not mean that the temperature inside the test tube can also be kept at 37 DEG C ± 1 DEG C, that is, there is an ineffective disaggregation condition.
[0006] 3, the water bath box is kept at 37 DEG C ± 1 DEG C for a long time, which is easy to breed bacteria and cause pollution, is a potential pollution source, and has biological safety risk.
[0007] 4, the water bath box can only remove the agglutination phenomenon of the blood sample specimen in the test tube, but cannot make the blood cells in the test tube mixed uniformly, and still affects the accuracy of the examination result.
[0008] Therefore, it is necessary to provide a new technology for removing red blood cell agglutination to solve the above technical problems. UTILITY MODEL CONTENT
[0009] The utility model discloses a purpose at overcoming prior art's above-mentioned technical problem provides an incubation mixed equipment of removing red blood cell agglutination, and the equipment adopts electric heating structure and can directly quickly effectively remove red blood cell agglutination phenomenon, and adopts the structure of circular rotation and upside -down and can make blood cell mix even, and the combination of both can effectively remove red blood cell agglutination and promote the accuracy of test result, in addition, the equipment can also stop rotating when the inspector is close to facilitate the taking of blood sample specimen, solve the inconvenient use of prior art, the energy consumption is relatively big, the temperature is not easy to accurate control, the bacteria is easy to breed, can not make blood cell mix even and the technical problem of inaccurate test result.
[0010] In order to realize the above-mentioned purpose, the utility model adopts the technical scheme as follows:
[0011] An incubation mixed equipment of removing red blood cell agglutination, comprising:
[0012] U-shaped seat, the U-shaped seat has two side support columns and the U-shaped groove between side support column, and the upper end of two side support columns is fixed with bearing seat;
[0013] Rotary mixing disc, the rotary mixing disc is rotatably arranged in the U-shaped groove through the shaft and bearing seat, and the circumference of rotary disc is evenly provided with a plurality of clamping holes;
[0014] Constant temperature electric heating incubation tube, the constant temperature electric heating incubation tube is clamped on the rotary mixing disc through the clamping hole, for keeping blood sample specimen at constant temperature 37±1°;
[0015] Driving motor, the driving motor is fixed on the side support column, for controlling the rotary mixing disc to rotate circularly 360° through the shaft;
[0016] Distance sensor, the distance sensor is installed on the side support column, for detecting whether there is inspector close;
[0017] PLC control assembly, the PLC control assembly is installed on the side support column and is connected with driving motor and distance sensor respectively, the PLC control assembly is used for controlling driving motor to stop working automatically when distance sensor detects that there is inspector close, and is used for controlling driving motor to restore work automatically after distance sensor detects that inspector leaves.
[0018] The number of distance sensor is two, and the two distance sensors are respectively on the upper part of two side support columns, and the two distance sensors are connected with the PLC control assembly, the PLC control assembly controls driving motor to stop working automatically when any distance sensor detects that there is inspector close, and the PLC control assembly controls driving motor to restore work automatically after both distance sensors detect that inspector leaves.
[0019] The clamping holes are arranged in at least two rings on the circumferential surface of the rotating mixing disc.
[0020] The constant-temperature electric heating incubation tube comprises a double-layer sleeve for placing a test tube, an electric heating wire is fixed inside a tube wall of the double-layer sleeve, a rechargeable lithium battery and a TYPE-C charging interface are fixed at a lower end of the double-layer sleeve, the lithium battery is electrically connected with the electric heating wire and the TYPE-C charging interface respectively, a tube cap is arranged at an upper end of the double-layer sleeve, a display control module is embedded in an outer wall of an upper portion of the double-layer sleeve, a temperature sensor is fixed in an inner wall of the upper portion of the double-layer sleeve, the display control module is connected with the electric heating wire and the temperature sensor respectively, the display control module is used for displaying an internal temperature of the double-layer sleeve detected by the temperature sensor and controlling starting and stopping of the electric heating wire according to the temperature detected by the temperature sensor.
[0021] The constant-temperature electric heating incubation tube has a length of 10-14 cm, an outer diameter of 2.2-2.8 cm and an inner diameter of 1.2-1.8 cm.
[0022] At least two annular clamping grooves distributed in an up-down direction are arranged on an inner wall of the clamping hole, a corresponding limiting protrusion is arranged on an outer wall of the double-layer sleeve, and the double-layer sleeve is clamped on the rotating mixing disc through the limiting protrusion and the annular clamping grooves.
[0023] A bottom cross section of the U-shaped seat is in isosceles trapezoidal structure.
[0024] The PLC control assembly is installed at a lower portion of the U-shaped seat.
[0025] The driving motor is fixed on the side supporting column through the support.
[0026] The utility model has the advantages that:
[0027] 1. The utility model discloses a constant temperature electric heating incubation tube can utilize the mode of electric heating to directly heat the blood sample specimen in the test tube, thereby can accurately control the blood sample specimen temperature at constant temperature 37±1 DEG, has played the effect of directly fast and effective removal of red blood cell agglutination phenomenon. In addition, through the clamping hole, the constant temperature electric heating incubation tube is fixed and taken on the rotating mixing disc, after fixing the constant temperature electric heating incubation tube on the rotating mixing disc, the rotating mixing disc is controlled to rotate using the drive motor, can make the blood cell mix evenly in the way of circular rotation and upside down, the combination of both can effectively remove the red blood cell agglutination and improve the accuracy of test result. In addition, through the distance sensor, whether the test personnel is close can be detected automatically, and the rotating mixing disc can be controlled to stop rotating automatically when detecting that the test personnel is close, and the rotating mixing disc can be controlled to restore rotating automatically through the drive motor after detecting that the test personnel leaves. Compared with the method of using the water bath box to remove the red blood cell agglutination of prior art, the utility model has the advantages of simpler structure, smaller size, more convenient use, less energy consumption, more accurate temperature control, less bacteria breeding, more uniform blood cell mixing, better agglutination removal effect and higher test result accuracy.
[0028] 2. The utility model discloses respectively set up distance sensor on two side support columns, it can detect whether the test personnel is close from two directions, has the advantage of accurate detection test personnel is close.
[0029] 3. The utility model discloses the clamping hole is annular and is evenly arranged on the circumferential surface of the rotating mixing disc, has the advantage that more constant temperature electric heating incubation tubes can be fixed and the constant temperature electric heating incubation tube is convenient to take and place.
[0030] 4. The utility model discloses the constant temperature electric heating incubation tube of specific structure, has the advantage that fast heating, convenient charging and the temperature in the double -layer sleeve is automatically kept at constant 37±1 DEG, also convenient to take and place the test tube.
[0031] 5. The utility model discloses through the cooperation of limiting protrusion and ring -shaped clamping groove, on the one hand, it can make the constant temperature electric heating incubation tube stably fixed on the rotating mixing disc, even if the rotating mixing disc is relatively fast rotating, the constant temperature electric heating incubation tube also can not fall from the rotating mixing disc. On the other hand, it also has the advantage that the constant temperature electric heating incubation tube is convenient to take and place on the rotating mixing disc.
[0032] 6. The utility model discloses the bottom cross section of U-shaped seat is isosceles trapezoidal structure, is favorable to the stability of the whole equipment. ACCURACY
[0033] Figure 1 It is the front view structure schematic drawing of the utility model discloses;
[0034] Figure 2This is a schematic diagram of the right-side structure of this utility model;
[0035] Figure 3 This is a schematic diagram of the structure of the constant temperature electric heating incubation tube in this utility model.
[0036] The following are labeled in the diagram: 1. U-shaped seat, 2. Rotating mixing disk, 3. Constant temperature electric heating incubation tube, 4. Drive motor, 5. Distance sensor, 6. PLC control component, 7. Bearing seat, 8. Locking hole, 9. Double-layer sleeve, 10. Electric heating wire, 11. Lithium battery, 12. TYPE-C charging interface, 13. Tube cap, 14. Display and control module, 15. Temperature sensor, 16. Limiting protrusion, 17. Test tube. Detailed Implementation
[0037] like Figures 1-2 As shown, this utility model provides an incubation and mixing device for removing red blood cell agglutination. The device can keep the blood sample in the test tube 17 at a constant temperature of 37±1°C, and can mix the blood cells in the test tube 17 evenly by circulating and inverting while maintaining a constant temperature, thereby achieving the purpose of effectively removing red blood cell agglutination and mixing evenly.
[0038] like Figures 1-2 As shown, the incubation and mixing equipment includes:
[0039] U-shaped seat 1, which has two side support columns and a U-shaped groove between the side support columns, the two vertical support columns are arranged vertically, and the upper ends of the two side support columns are fixed with bearing seats 7.
[0040] Furthermore, to improve the stability of the equipment during operation, it is preferable that the bottom cross-section of the U-shaped base 1 is an isosceles trapezoidal structure, which can provide a more stable support effect for other structures on the U-shaped base 1.
[0041] A rotating mixing disc 2 has a centrally located rotating shaft fixed to it via a spline or similar structure. Both ends of the shaft extend and are fixed within bearing seats 7 on two side support columns, allowing the mixing disc 2 to be rotatably mounted within a U-shaped groove via the shaft and bearing seats 7. The mixing disc 2 has a solid annular structure of a certain thickness, with multiple evenly distributed locking holes 8 on its circumference. The mixing disc can be made of lightweight yet structurally strong environmentally friendly rubber material.
[0042] Multiple thermostatic electric heating incubation tubes 3 are provided, each secured to the rotating mixing disk 2 via a locking hole 8. A test tube 17 for collecting blood samples can be placed inside the thermostatic electric heating incubation tube 3, and its function is to maintain the blood sample at a constant temperature of 37±1°C through electric heating.
[0043] A driving motor 4 is fixed on the side supporting column through a support and is used to control the rotating mixing disc 2 to rotate 360 degrees on the U-shaped seat 1 through a rotating shaft, so that the blood sample in the constant temperature electric heating incubation tube 3 can be mixed uniformly in a circulating rotation and upside-down manner.
[0044] A distance sensor 5 is installed on the side supporting column and is used to detect whether there is an inspector nearby and send a signal to the PLC control assembly 6 when detecting that there is an inspector nearby and detecting that there is an inspector leaving.
[0045] The PLC control assembly 6 is installed on the side supporting column and can be installed at the lower part of the U-shaped seat 1. The PLC control assembly 6 is connected with the driving motor 4 and the distance sensor 5 respectively, is used to receive the detection information sent by the distance sensor 5, and controls the driving motor 4 to stop working automatically when the distance sensor 5 detects that there is an inspector nearby and controls the driving motor 4 to restore working automatically when the distance sensor 5 detects that the inspector leaves.
[0046] As can be understood by those skilled in the art, the PLC control assembly 6 generally comprises a PLC controller, a display and a relay and other related conventional structural parts. In addition to controlling the driving motor 4 according to the detection information of the distance sensor 5, the PLC control assembly 6 can also control the driving motor 4 to start and stop independently, can set the rotating speed of the driving motor 4, and can send the rotating speed information of the driving motor 4 to the display for display.
[0047] According to a preferred embodiment of the utility model, as shown in Figure 1 The number of the distance sensor 5 is two, and the two distance sensors 5 are respectively arranged at the upper parts of the two side supporting columns and are used to detect whether there is an inspector nearby from two different directions. The two distance sensors 5 are connected with the PLC control assembly 6, and the PLC control assembly 6 controls the driving motor 4 to stop working automatically when any one of the distance sensors 5 detects that there is an inspector nearby. At this time, the rotating mixing disc 2 is in a state of stopping rotating, which is convenient for the inspector to take and place the constant temperature electric heating incubation tube 3 from the rotating mixing disc 2. The PLC control assembly 6 controls the driving motor 4 to restore working automatically when both of the distance sensors 5 detect that the inspector leaves. At this time, the rotating mixing disc 2 is in a state of rotating, and the blood sample in the constant temperature electric heating incubation tube 3 will be mixed uniformly in a circulating rotation and upside-down manner.
[0048] According to an optional embodiment of the utility model, as shown in Figure 1 The clamping holes 8 are arranged in at least two rings on the circumferential surface of the rotating mixing disc 2, so that more constant temperature electric heating incubation tubes 3 can be carried on the rotating mixing disc 2, and the constant temperature electric heating incubation tubes 3 are convenient to take and place.
[0049] According to another preferred embodiment of the utility model, as shown in Figure 3 As shown in the figure, the constant-temperature electric heating incubation tube 3 is in a cylindrical structure, which comprises a double-layer sleeve 9 for placing a test tube 17, an electric heating wire 10 fixed inside the tube wall of the double-layer sleeve 9, a rechargeable lithium battery 11 and a TYPE-C charging interface 12 fixed at the lower end of the double-layer sleeve 9, the lithium battery 11 being electrically connected with the electric heating wire 10 and the TYPE-C charging interface 12 respectively, the lithium battery 11 being a 5V battery, which provides electric energy for the electric heating wire 10 to generate heat, and the TYPE-C charging interface 12 being used for quickly charging the lithium battery 11. A pipe cap 13 is arranged at the upper end of the double-layer sleeve 9, a display control module 14 is embedded in the outer wall of the upper part of the double-layer sleeve 9, and a temperature sensor 15 is fixed on the inner wall of the upper part of the double-layer sleeve 9. The display control module 14 is connected with the electric heating wire 10 and the temperature sensor 15 respectively, and is used for setting the heating temperature of the electric heating wire 10, displaying the internal temperature of the double-layer sleeve 9 detected by the temperature sensor 15, controlling the start and stop of the electric heating wire 10 according to the temperature detected by the temperature sensor 15, and keeping the temperature of the double-layer sleeve 9 at 37±1° at all times through the device.
[0050] Further, the length of the constant-temperature electric heating incubation tube 3 can be 10-14cm, the outer diameter can be 2.2-2.8cm, and the inner diameter can be 1.2-1.8cm. Preferably, the length of the constant-temperature electric heating incubation tube 3 is 12cm, the outer diameter can be 2.5cm, and the inner diameter can be 1.5cm.
[0051] According to another preferred embodiment of the utility model, as shown in Figure 3 As shown in the figure, at least two annular clamping grooves (not shown in the figure) are arranged on the inner wall of the clamping hole 8, a limiting protrusion 16 is arranged on the outer wall of the double-layer sleeve 9, and the double-layer sleeve 9 is clamped on the rotating mixing disc 2 through the limiting protrusion 16 and the annular clamping groove. On the one hand, the detection personnel only need to use a little larger pulling force or pressure to take out or put the double-layer sleeve 9 into the clamping hole 8, and on the other hand, the double-layer sleeve 9 can be stably fixed in the clamping hole 8 and will not fall out under the cooperation of the limiting protrusion 16 and the annular clamping groove.
[0052] The use principle of the utility model is as follows:
[0053] The test tube 17 with blood sample is put into the constant temperature electric heating incubation tube 3, the electric heating wire 10 is controlled to heat by the display control module 14, and the blood sample is kept at 37±1° all the time, so that the red blood cell agglutination in the sample can be effectively removed. Then the constant temperature electric heating incubation tube 3 is inserted into the clamping hole 8 of the rotating mixing disc 2, the rotating mixing disc 2 is controlled to rotate by the PLC control assembly 6, the constant temperature electric heating incubation tube 3 is rotated and upside down by the rotating mixing disc 2, so that the blood cells are mixed uniformly, and the red blood cell agglutination is effectively removed and the accuracy of the test result is improved.
[0054] In addition, during the work, when the distance sensor 5 detects that the tester approaches, the rotating mixing disc 2 is automatically stopped to rotate by the PLC control assembly 6 through the driving motor 4, so that the tester can take and place the constant temperature electric heating incubation tube 3 from the rotating mixing disc 2. When the distance sensor 5 detects that the tester leaves, the rotating mixing disc 2 is automatically restored to rotate by the PLC control assembly 6 through the driving motor 4, so that the blood sample in the constant temperature electric heating incubation tube keeps mixing.
[0055] The above is only a specific implementation of the present application, any feature disclosed in the specification can be replaced by other equivalent or similar purpose replacement features, unless specifically described; all features disclosed, or steps in all methods or processes, except for mutually exclusive features and / or steps, can be combined in any way.
Claims
1. An incubation mixing device for removing rouleaux of red blood cells, characterized in that The utility model relates to a blood sample mixing device, including: U-shaped seat (1), the U-shaped seat (1) has two side support columns and the U-shaped groove between side support column, and the upper end of two side support columns is fixed with bearing seat (7); Rotary mixing disc (2), the rotary mixing disc (2) is rotatably arranged in the U-shaped groove through the rotating shaft and bearing seat (7), and the circumferential surface of rotary disc is evenly provided with a plurality of clamping holes (8); Constant temperature electric heating incubation tube (3), the constant temperature electric heating incubation tube (3) is clamped in rotary mixing disc (2) through clamping hole (8), is used for keeping blood sample specimen in constant temperature 37±1 DEG C; Driving motor (4), the driving motor (4) is fixed on side support column, is used for controlling rotary mixing disc (2) to rotate circularly 360 DEG through rotating shaft; Distance sensor (5), the distance sensor (5) is installed on side support column, is used for detecting whether there is inspection personnel close; PLC control assembly (6), the PLC control assembly (6) is installed on side support column and is connected with driving motor (4) and distance sensor (5) respectively, the PLC control assembly (6) is used for controlling driving motor (4) to stop working automatically when distance sensor (5) detects that there is inspection personnel close, and is used for controlling driving motor (4) to restore work automatically after distance sensor (5) detects that inspection personnel leaves.
2. The incubation mixing device for removing erythrocyte agglutination according to claim 1, characterized in that: The number of distance sensor (5) is two, two distance sensors (5) are respectively in the upper portion of two side support columns, two distance sensors (5) are connected with PLC control assembly (6), PLC control assembly (6) controls driving motor (4) to stop working automatically when any distance sensor (5) detects that there is inspection personnel close, and PLC control assembly (6) controls driving motor (4) to restore work automatically after two distance sensors (5) all detect that inspection personnel leaves.
3. The incubation mixing device for removing erythrocyte agglutination according to claim 1, characterized in that: The clamping hole (8) is arranged at least in two rings on the circumferential surface of rotary mixing disc (2).
4. The incubation mixing device for removing erythrocyte agglutination according to any one of claims 1 to 3, characterized in that: The constant temperature electric heating incubation tube (3) includes double-layer sleeve (9) for placing test tube (17), electric heating wire (10) is fixed in the pipe wall inside of double-layer sleeve (9), rechargeable lithium battery (11) and TYPE-C charging interface (12) are fixed in the lower end of double-layer sleeve (9), lithium battery (11) is electrically connected with electric heating wire (10) and TYPE-C charging interface (12) respectively;Pipe cap (13) is arranged on the upper end of double-layer sleeve (9), display control module (14) is embedded in the outer wall of the upper portion of double-layer sleeve (9), temperature sensor (15) is fixed in the inner wall of the upper portion of double-layer sleeve (9), display control module (14) is connected with electric heating wire (10) and temperature sensor (15) respectively, display control module (14) is used for displaying the internal temperature of double-layer sleeve (9) detected by temperature sensor (15), and is used for controlling the start and shutdown of electric heating wire (10) according to the temperature detected by temperature sensor (15).
5. The incubation mixing device for removing erythrocyte agglutination according to claim 4, characterized in that: The length of the constant temperature electric heating incubation tube (3) is 10-14cm, the outer diameter is 2.2-2.8cm, and the inner diameter is 1.2-1.8cm.
6. The incubation mixing device for removing erythrocyte agglutination according to claim 4, characterized in that: The inner wall of the clamping hole (8) is provided with at least two annular clamping grooves distributed in upper and lower positions, and the outer wall of the double-layer sleeve (9) is provided with corresponding limiting protrusions (16), and the double-layer sleeve (9) is clamped on the rotating mixing disc (2) through the limiting protrusions (16) and the annular clamping grooves.
7. The incubation mixing device for removing red blood cell agglutination according to claim 1, characterized in that: The bottom cross section of the U-shaped seat (1) is isosceles trapezoidal structure.
8. The incubation mixing device for removing red blood cell agglutination according to claim 1, characterized in that: The PLC control assembly (6) is installed at the lower part of the U-shaped seat (1).
9. The incubation mixing device for removing erythrocyte agglutination according to claim 1, characterized in that: The driving motor (4) is fixed on the side supporting column through a support.