Vacuum pressing quantitative blood collection tube suitable for flow type experiment

Abstract

The utility model relates to the field of blood collection tubes, and discloses a vacuum pressing quantitative blood collection tube suitable for a flow type experiment, which comprises a tube body used for storing blood; the sealing plug is mounted in the tube body, moves in the tube body when negative pressure is formed in the tube body and is used for pushing blood in the tube body; and the pump head mechanism is mounted at the opening of the pipe body. By means of the design of the sealing plug and the pump head mechanism, negative pressure control in the blood sampling process is guaranteed, blood can be effectively prevented from spilling, safety and accuracy in the blood sampling process are improved, the pump output of the pump head can be conveniently adjusted through movement of the adjusting ring on the pump head mechanism, accurate control over blood flow is achieved, and the blood sampling device is convenient to use. Different requirements of different experiments for blood volume are met, the blood collection tube has better sealing performance, and the sealing performance of the pump head mechanism in the blood collection and storage process is ensured.

Description

Technical Field

[0001] This utility model relates to the field of blood collection tubes, and in particular to a vacuum-pressed quantitative blood collection tube suitable for flow cytometry experiments. Background Technology

[0002] There are two main types of blood collection tubes commonly used in flow cytometry: green-tipped blood collection tubes with heparin sodium anticoagulation and purple-tipped blood collection tubes with EDTA anticoagulation.

[0003] Existing vacuum blood collection tubes, due to their negative pressure design, may cause blood to spill if handled improperly during blood collection, such as if the test tube is not upright on the test tube rack or is tilted at too large an angle. Non-vacuum blood collection tubes do not have caps or are not tightly sealed, making them prone to dust, bacteria, and mold growth if left for a long time, which can cause testing errors. In addition, blood collection tubes cannot provide quantitative blood addition. Utility Model Content

[0004] To solve the problems mentioned above, this utility model achieves its goals through the following technical solution:

[0005] A vacuum-pressable quantitative blood collection tube suitable for flow cytometry includes: a tube body for storing blood; a sealing plug installed inside the tube body and configured to move within the tube body when a negative pressure is generated inside the tube body to push the blood within the tube body; a pump head mechanism installed at the opening of the tube body for pumping out the blood from the tube body; and an adjusting ring disposed on the pump head mechanism and configured to move on the pump head mechanism to adjust the pumping volume of the pump head mechanism.

[0006] The pump head mechanism includes: a pipe cap, mounted on the pipe body; a valve plate, mounted inside the pipe cap, covering the opening of the pipe body; an inlet valve ball, disposed on the valve plate; a piston cap, mounted inside the pipe cap; a reservoir, disposed inside the pipe cap and connected to the piston cap; and an elastic element, one end connected to the inner wall of the piston cap and the other end connected to the valve plate, the elastic element being used to provide a restoring force for the piston cap to its initial position.

[0007] The pump head mechanism also includes: a connecting pipe, which passes through the pipe cover and is connected to the piston cover; an adjusting ring connected to the connecting pipe; a discharge valve ball, which is disposed inside the connecting pipe; a pressing head, which is installed on the connecting pipe; a discharge pipe, which is installed on the pressing head and is connected to the connecting pipe; and a protective cover, which is installed on the pipe cover and the pressing head is covered inside the protective cover.

[0008] The connecting pipe has a threaded groove, and the adjusting ring is connected to the threaded groove.

[0009] The pipe cap and the pipe body are connected by threads.

[0010] The pressing head has a channel for connecting the liquid outlet pipe and the connecting pipe.

[0011] A through hole is formed on the valve plate, and the liquid inlet valve ball is installed in the through hole.

[0012] This invention provides a vacuum-pressurized quantitative blood collection tube suitable for flow cytometry experiments. Compared with existing technologies, it has the following advantages:

[0013] 1. The design of the sealing plug and pump head mechanism ensures negative pressure control during the blood collection process. Even if the test tube is not completely upright on the test tube rack or has a certain tilt angle, the presence of the sealing plug and the precise control of the pump head mechanism can effectively prevent blood spillage, thus improving the safety and accuracy of the blood collection process.

[0014] 2. By adjusting the movement of the adjusting ring on the pump head mechanism, the pump output of the pump head can be easily adjusted, achieving precise control of blood flow. This meets the different blood volume requirements of different experiments, enabling the blood collection tube to be quantitatively filled, thus improving the accuracy and repeatability of the experiment.

[0015] 3. The blood collection tube has better sealing performance, ensuring the sealing of the pump head mechanism during blood collection and storage, effectively preventing the intrusion of contaminants such as dust, bacteria, and mold, and reducing testing errors. Attached Figure Description

[0016] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0017] Figure 2 This is a three-dimensional structural diagram from another perspective of the present invention.

[0018] Figure 3 This is a schematic diagram of the exploded structure proposed in this utility model.

[0019] Figure 4 This is a schematic diagram of the cross-sectional structure proposed in this utility model.

[0020] Figure 5 This is a schematic diagram of the cross-sectional structure of the pump head mechanism proposed in this utility model.

[0021] The attached figures are labeled as follows:

[0022] 1. Pipe body; 101. Sealing plug;

[0023] 2. Pump head mechanism; 201. Pipe cover; 202. Piston cover; 203. Liquid reservoir; 204. Valve plate; 205. Elastic element; 206. Inlet valve ball; 207. Connecting pipe; 208. Outlet valve ball; 209. Press head; 210. Outlet pipe; 211. Threaded groove; 212. Protective cover;

[0024] 3. Adjusting ring. Detailed Implementation

[0025] The present invention will be further described below with reference to specific embodiments. It should be understood that these embodiments are only used to illustrate the present invention and are not intended to limit the scope of protection of the present invention.

[0026] The following specific examples illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification. This utility model can also be implemented or applied through other different specific embodiments, and various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of this utility model.

[0027] Reference Figures 1-5 A vacuum-pressable quantitative blood collection tube suitable for flow cytometry experiments includes: a tube body 1 for storing blood. The tube body 1 serves as the primary blood storage container, ensuring safe blood storage during experiments. Its design also facilitates assembly with other components, providing a stable foundation for flow cytometry experiments. A sealing plug 101, installed inside the tube body 1, is configured to move within the tube body 1 when a negative pressure is created, thereby agitating the blood within the tube body 1. The sealing plug 101's ability to move under negative pressure effectively prevents external air from entering the tube body 1, ensuring blood purity, and its movement agitates the blood within the tube body 1, achieving quantitative blood collection. The transmission mechanism improves the accuracy and efficiency of the experiment. The pump head mechanism 2, installed at the opening of the tube 1, is used to pump out the blood in the tube 1. The design of the pump head mechanism 2 allows the blood in the tube 1 to be pumped out accurately and controllably, providing a stable blood flow for flow cytometry experiments, which helps to improve the accuracy and repeatability of experimental results. The adjustment ring 3, set on the pump head mechanism 2, is designed to move on the pump head mechanism 2 to adjust the pumping volume of the pump head mechanism 2. By moving the adjustment ring 3 on the pump head mechanism 2, the pumping volume of the pump head can be easily adjusted, achieving precise control of blood flow, meeting the different blood volume requirements of different experiments, and increasing the flexibility and practicality of the experiment.

[0028] The pump head mechanism 2 includes: a pipe cap 201, installed on the pipe body 1; a valve plate 204, installed inside the pipe cap 201, covering the opening of the pipe body 1; and an inlet valve ball 206, disposed on the valve plate 204, which has a through hole. The inlet valve ball 206 is disposed within the through hole, and the valve plate 204 covers the opening of the pipe body 1. The valve ball 206 cooperates with the inlet valve ball 206 to control the inflow and outflow of blood, ensuring the sealing and accuracy of the pump head during the pumping process, preventing blood leakage and backflow. When the pump head generates negative pressure, the inlet valve ball 206 is opened, allowing blood to enter the pump head; when the pressure inside the pump head increases, the inlet valve ball 206 closes to prevent blood backflow and ensure... The system ensures unidirectional blood flow and accurate collection. The piston cap 202, installed inside the tube cap 201, utilizes the restoring force of the elastic element 205 to ensure stable movement and repositioning of the piston cap 202 during the pumping process, providing reliable mechanical support for the continuous operation of the pump head. The reservoir 203, located inside the tube cap 201 and connected to the piston cap 202, serves as a temporary blood storage space inside the pump head, helping to smooth blood flow, reduce fluctuations during pumping, and improve the pumping efficiency and stability. The elastic element 205, with one end connected to the inner wall of the piston cap 202 and the other end connected to the valve plate 204, is used to provide support for the pump head. The plug cap 202 provides a restoring force for the initial position. The elastic element 205 is a stainless steel spring, but an alloy spring can also be used. The connecting pipe 207 passes through the pipe cap 201 and connects to the piston cap 202. The adjusting ring 3 is connected to the connecting pipe 207. A threaded groove 211 is formed on the connecting pipe 207, and the adjusting ring 3 is connected to the threaded groove 211. The connecting pipe 207 not only passes through the pipe cap 201 and connects to the piston cap 202, but also connects to the adjusting ring 3 through the threaded groove 211, realizing the communication between the inside and outside of the pump head. At the same time, it facilitates the installation and adjustment of the adjusting ring 3, providing structural support for the precise control of the pump head. The discharge valve ball 208 is set inside the connecting pipe 207. When the pressure inside the pump head increases... When the pressure inside the pump head decreases, the discharge valve ball 208 is pushed open, allowing blood to flow out; when the pressure inside the pump head decreases, the discharge valve ball 208 closes, preventing external air or liquid from entering the pump head, ensuring the pump head's sealing and the unidirectional flow of blood; the pressing head 209 is installed on the connecting pipe 207; the protective cover 212 is installed on the pipe cover 201, and the pressing head 209 is covered inside the protective cover 212, which provides dust and pollution protection for the pressing head 209 and the discharge pipe 210; the discharge pipe 210 is installed on the pressing head 209, and the discharge pipe 210 is connected to the connecting pipe 207. The pressing head 209 has a channel for connecting the discharge pipe 210 and the connecting pipe 207.

[0029] The pipe cap 201 is connected to the pipe body 1 by threads.

[0030] During use, open the opening of tube 1 and inject blood into tube 1 until the required volume is reached. Ensure that the sealing plug 101 is correctly installed and sealed to prevent outside air from entering tube 1. Confirm that both the inlet valve ball 206 and the outlet valve ball 208 are in the closed state to ensure the internal sealing of the pump head. Securely install the tube cap 201 onto tube 1 using the threaded connection to ensure the stability of the pump head mechanism 2. Adjust the position of the adjusting ring 3 on the connecting pipe 207 according to experimental requirements to set the pump output of the pump head. Manually press the pressing head 209 to move the piston cap 202 downward through mechanical force, compressing the space inside the reservoir 203 and creating a negative pressure inside the pump head. Under the action of the negative pressure, the inlet valve ball 206 is drawn open, allowing blood to enter the pump head from tube 1 and fill the reservoir 203 and connecting pipe 207. In part of the space 7, when the piston cover 202 moves upward, the internal pressure of the pump head increases, the inlet valve ball 206 closes to prevent blood backflow, and at the same time, the outlet valve ball 208 is pushed open, allowing blood to flow out from the connecting tube 207 and enter the receiving container or experimental device through the outlet tube 210. During the blood pumping process, if it is necessary to adjust the pumping volume, it can be achieved by moving the position of the adjusting ring 3 on the connecting tube 207. The movement of the adjusting ring 3 will adjust the distance that the connecting tube 207 can move, thereby adjusting the pumping speed and total volume of the pump head. When the pressing head 209 is released, the elastic element 205 drives the piston cover 202 and the connecting tube 207 to reset and move, the inlet valve ball 206 is pushed open, and the blood in the tube 1 re-enters the reservoir 203 under negative pressure. The sealing plug 101 moves upward and pushes the blood to move.

[0031] In summary, compared with existing technologies, it has the following beneficial effects:

[0032] The design of the sealing plug 101 and the pump head mechanism 2 ensures negative pressure control during the blood collection process. Even if the test tube is not completely upright on the test tube rack or has a certain tilt angle, the presence of the sealing plug 101 and the precise control of the pump head mechanism 2 can effectively prevent blood spillage, thus improving the safety and accuracy of the blood collection process.

[0033] By adjusting the movement of the adjusting ring 3 on the pump head mechanism 2, the pumping volume of the pump head can be easily adjusted, achieving precise control of blood flow. This meets the different blood volume requirements of different experiments, enabling the blood collection tube to be quantitatively filled, thus improving the accuracy and repeatability of the experiment.

[0034] The blood collection tube has better sealing performance, ensuring the sealing of the pump head mechanism 2 during blood collection and storage, effectively preventing the intrusion of contaminants such as dust, bacteria, and mold, and reducing testing errors.

[0035] Therefore, although the present invention has been described herein with reference to specific embodiments thereof, freedom of modification, various changes and substitutions are also within the scope of the above disclosure, and it should be understood that in some cases, certain features of the present invention may be adopted without departing from the scope and spirit of the invention and without corresponding use of other features. Thus, many modifications can be made to adapt a particular environment or material to the essential scope and spirit of the present invention. The present invention is not intended to be limited to the specific terms used in the following claims and / or the specific embodiments disclosed as the best mode of carrying out the present invention, but the present invention will include any and all embodiments and equivalents falling within the scope of the appended claims. Therefore, the scope of the present invention will be determined only by the appended claims.

Claims

1. A vacuum-pressable quantitative blood collection tube suitable for flow cytometry experiments, characterized in that, include: The tube (1) is used to store blood; A sealing plug (101) is installed inside the tube body (1) and is configured to move inside the tube body (1) when a negative pressure is formed inside the tube body (1) to push the blood inside the tube body (1); A pump head mechanism (2) is installed at the opening of the tube body (1) for pumping out blood from the tube body (1); An adjusting ring (3) is provided on the pump head mechanism (2) and is configured to move on the pump head mechanism (2) to adjust the pump output of the pump head mechanism (2).

2. The vacuum-pressed quantitative blood collection tube suitable for flow cytometry experiments according to claim 1, characterized in that, The pump head mechanism (2) includes: A pipe cap (201) is installed on the pipe body (1); A valve plate (204) is installed inside the pipe cover (201) and covers the opening of the pipe body (1); An inlet valve ball (206) is disposed on the valve plate (204); Piston cap (202) is installed inside the tube cap (201); A liquid storage cylinder (203) is disposed inside the tube cap (201) and connected to the piston cap (202); The elastic element (205) is connected at one end to the inner wall of the piston cover (202) and at the other end to the valve plate (204). The elastic element (205) is used to provide the piston cover (202) with a restoring force for the initial position.

3. A vacuum-pressed quantitative blood collection tube suitable for flow cytometry experiments according to claim 2, characterized in that, The pump head mechanism (2) also includes: A connecting pipe (207) passes through the pipe cover (201) and is connected to the piston cover (202); the adjusting ring (3) is connected to the connecting pipe (207); The liquid outlet valve ball (208) is disposed inside the connecting pipe (207); A pressing head (209) is installed on the connecting pipe (207); A protective cover (212) is installed on the tube cap (201), and the pressing head (209) is covered inside the protective cover (212).

4. A vacuum-pressurized quantitative blood collection tube suitable for flow cytometry experiments according to claim 3, characterized in that, The pump head mechanism (2) also includes: The liquid outlet pipe (210) is installed on the pressing head (209) and is connected to the connecting pipe (207).

5. A vacuum-pressurized quantitative blood collection tube suitable for flow cytometry experiments according to claim 3, characterized in that, A threaded groove (211) is formed on the connecting pipe (207), and the adjusting ring (3) is connected to the threaded groove (211).

6. A vacuum-pressurized quantitative blood collection tube suitable for flow cytometry experiments according to claim 2, characterized in that, The pipe cap (201) and the pipe body (1) are connected by threads.

7. A vacuum-pressed quantitative blood collection tube suitable for flow cytometry experiments according to claim 4, characterized in that, The pressing head (209) has a channel for connecting the liquid outlet pipe (210) and the connecting pipe (207).

8. A vacuum-pressed quantitative blood collection tube suitable for flow cytometry experiments according to claim 2, characterized in that, A through hole is formed on the valve plate (204), and the liquid inlet valve ball (206) is disposed in the through hole.

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