Storable antibody incubation box
By designing a storable antibody incubation box, the problem of poor sealing of traditional antibody incubation boxes is solved, achieving stable antibody storage, simplifying experimental operations, and reducing costs.
Patent Information
- Application Number
- CN202422418376.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-08
- Publication Date
- 2025-11-11
- Estimated Expiration
- 2034-10-08
AI Technical Summary
Traditional antibody incubation boxes have poor sealing properties, which leads to antibody loss and degradation during transfer, increasing experimental costs and time.
A storable antibody incubation box with good sealing performance was designed, including a closed cover and a movable cover, which can directly store antibodies, reduce the transfer process, and provide sealing and opening functions to prevent external air and impurities from entering.
Maintaining antibody stability, reducing loss and degradation, saving operation time, simplifying experimental procedures, reducing material costs, and improving ease of operation.
Smart Images

Figure CN223534005U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of antibody storage, and in particular to a storable antibody incubation box. Background Technology
[0002] Antibody incubation is a common technique in biological and medical research, primarily used to detect specific antigens or analyze protein-protein interactions. After the antibody has completed the experiment in the antibody incubation chamber, it needs to be transferred back to a centrifuge tube. Traditional antibody incubation chambers, due to their poor sealing, cannot store antibodies effectively, leading to antibody loss and making direct antibody storage impossible. Furthermore, the process of transferring antibodies from the antibody incubation chamber to the centrifuge tube also has many shortcomings.
[0003] For example, during the process of transferring antibodies from the antibody incubation cassette to centrifuge tubes, some antibodies may be lost due to improper handling or other factors. Additionally, antibodies may be affected by temperature changes, light exposure, and other factors during transfer, leading to antibody degradation and reduced activity and stability. Finally, storing the antibodies back in centrifuge tubes requires additional time and handling, potentially increasing the time cost of the experiment.
[0004] Therefore, we need an antibody incubation box that can store antibodies so that after antibody incubation experiments, the antibodies do not need to be stored back into centrifuge tubes, but can be stored directly in the antibody incubation box. Utility Model Content
[0005] One advantage of this invention is that it provides a storable antibody incubation box, which can be used directly to store antibodies. After antibody incubation experiments, there is no need to re-store the antibodies in centrifuge tubes.
[0006] Another advantage of this invention is that it provides a storable antibody incubation box, which provides good sealing and helps maintain the stability of the antibody.
[0007] Another advantage of this invention is that it provides a storable antibody incubation box, which can be used directly to store antibodies, reducing the risk of antibody loss during the transfer process.
[0008] Another advantage of this invention is that it provides a storable antibody incubation box, which can be used directly to store antibodies, avoiding the process of frequent antibody transfer and reducing the possibility of contamination.
[0009] Another advantage of this invention is that it provides a storable antibody incubation box, which can be used directly to store antibodies without transferring them to centrifuge tubes, thus saving operation time.
[0010] Another advantage of this invention is that it provides a storable antibody incubation box, which eliminates the need for additional materials such as centrifuge tubes, thus saving on experimental material costs.
[0011] Another advantage of this utility model is that it provides a storable antibody incubation box, which can be used to complete experiments and store antibodies, simplifying the experimental procedure.
[0012] Another advantage of the utility model is that it provides a storable antibody incubation box, wherein the storable antibody incubation box has a sealing element surrounding the first side edge, the second side edge and the extended edge on the inner surface of the movable cover, which helps to improve the sealing performance of the storable antibody incubation box and prevent antibody loss.
[0013] Another advantage of the utility model is that it provides a storable antibody incubation box, wherein the sealing portion where the sealing cover of the storable antibody incubation box is located provides good sealing performance, which helps to maintain the stability of the antibody and reduce the evaporation and leakage of the antibody.
[0014] Another advantage of this utility model is that it provides a storable antibody incubation box. When the opening part of the movable cover of the storable antibody incubation box is closed, it can effectively prevent the entry of external air and impurities. At the same time, it can be easily opened when needed, so that the experimenters can flexibly control the experimental environment when conducting antibody incubation experiments, which not only meets the experimental requirements but also improves the convenience of operation.
[0015] Another advantage of the utility model is that it provides a storable antibody incubation box, which is configured to be stored in a box housing with the closed part facing down when placed, and the closed cover and the bottom box assembly are in a completely closed state, so that the antibody will not overflow from the storage cavity.
[0016] According to another aspect of the present invention, the present invention further provides a storable antibody incubation box, comprising:
[0017] A base box assembly having a storage cavity; and
[0018] A cover assembly is disposed above the base box assembly. The cover assembly includes a closed cover and a movable cover. The closed cover is integrally connected to the base box assembly. The movable cover is openably disposed above the base box assembly and fits against the closed cover. An antibody is suitable for storage in the storage cavity.
[0019] According to one embodiment of the present invention, the storable antibody incubation box further includes a sealing part and an opening part, the sealing cover is disposed in the sealing part, and the movable cover is disposed in the opening part.
[0020] According to one embodiment of the present invention, when the antibody is stored in the storage cavity, the storable antibody incubation box is configured to be housed in a box shell with the closed portion facing downwards.
[0021] According to one embodiment of the present invention, the closed cover includes an extension member, having three closed sides and a fitting side. The closed sides are integrally connected to the upper end of the bottom box assembly to fix the closed cover to the bottom box assembly. The fitting side is adapted to fit against the movable cover. The extension member extends outward from the fitting side. When the movable cover is in a closed state, the side of the movable cover near the fitting side is adapted to cover the extension member.
[0022] According to one embodiment of the present invention, the movable cover includes a cover portion and an extension portion, the extension portion being bent outward from the cover portion to connect to the bottom box assembly, the extension portion having an inner surface, the inner surface of the extension portion being adapted to fit against the outer surface of the bottom box assembly.
[0023] According to one embodiment of the present invention, the movable cover further includes a first fixing component and a second fixing component. The first fixing component is disposed on the inner surface of the extension, and the second fixing component is disposed on the outer surface of the bottom box assembly. The first fixing component and the second fixing component are adapted to be connected and fixed to each other.
[0024] According to one embodiment of the present invention, the cover portion has a first side edge, a second side edge, an extended edge, and a fixed edge. The fixed edge is connected above the bottom box assembly to fix one side of the movable cover to the bottom box assembly. The extended edge is disposed between the cover portion and the extension portion to connect the cover portion and the extension portion. The first side edge is adapted to fit against the fitting edge of the closed cover, and the second side edge is adapted to fit against the top of the bottom box assembly.
[0025] According to one embodiment of the present invention, the length of the long side of the bottom box assembly is set to 80mm to 100mm, the length of the short side of the bottom box assembly is set to 50mm to 70mm, and the total height of the bottom box assembly and the cover assembly is set to 25mm to 45mm.
[0026] According to one embodiment of the present invention, the amount of antibody stored in the storage cavity is no more than half the volume of the storage cavity.
[0027] According to one embodiment of the present invention, the storable antibody incubation box further includes a sealing member disposed on the inner surface of the movable cover and surrounding the first side edge, the second side edge and the extended edge.
[0028] The further objectives and advantages of this invention will become fully apparent from the following description and accompanying drawings. Attached Figure Description
[0029] Figure 1 This is one of the overall structural schematic diagrams of a storable antibody incubation box according to the first embodiment of the present invention.
[0030] Figure 2 This is the second schematic diagram of the overall structure of a storable antibody incubation box according to the first embodiment of the present invention.
[0031] Figure 3 This is a schematic diagram of an antibody placed in a storable antibody incubation box according to a first embodiment of the present invention.
[0032] Figure 4 This is a schematic diagram of a storable antibody incubation box according to the first embodiment of the present invention, housed in a box shell.
[0033] Figure 5 This is one of the overall structural schematic diagrams of a storable antibody incubation box according to the second embodiment of the present invention.
[0034] Figure 6 This is the second schematic diagram of the overall structure of a storable antibody incubation box according to the second embodiment of the present invention. Detailed Implementation
[0035] The following description is intended to disclose the present invention so that those skilled in the art can implement it. The preferred embodiments described below are merely examples, and other obvious variations will occur to those skilled in the art. The basic principles of the present invention defined in the following description can be applied to other embodiments, modifications, improvements, equivalents, and other technical solutions that do not depart from the spirit and scope of the present invention.
[0036] Those skilled in the art should understand that, in the disclosure of this utility model, the terms "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, the above terms should not be construed as limitations on this utility model.
[0037] It is understood that the term "a" should be understood as "at least one" or "one or more", that is, in one embodiment, the number of an element can be one, while in another embodiment, the number of the element can be multiple, and the term "a" should not be understood as a limitation on the number.
[0038] Reference Appendix Figure 1 To be continued Figure 4 As shown, a storable antibody incubation box according to a preferred embodiment of the present invention is illustrated. The storable antibody incubation box 1 can be directly used to store an antibody. After antibody incubation experiments, there is no need to re-store the antibody in a centrifuge tube, reducing the risk of antibody loss during transfer. Furthermore, the storable antibody incubation box 1 provides good sealing, which helps maintain stability.
[0039] Figure 1 This is a schematic diagram of the overall structure of the storable antibody incubation box 1 according to a first preferred embodiment of the present invention. In this embodiment, the storable antibody incubation box 1 includes a bottom box assembly 10 and a cover assembly 20. The cover assembly 20 is disposed above the bottom box assembly 10, thereby the bottom box assembly 10 provides support and fixation for the cover assembly 20. The bottom box assembly 10 has a storage cavity 11, and the cover assembly 20 covers the bottom box assembly 10 to seal the storage cavity 11. The antibody is adapted to be stored in the storage cavity 11.
[0040] The cover assembly 20 includes a closed cover 21 and a movable cover 22. The closed cover 21 is integrally connected to the top of the base box assembly 10, and the movable cover 22 is openably disposed above the base box assembly 10 and fitted to the closed cover 21. In other words, the closed cover 21, through its integrated design, is firmly connected to the top of the base box assembly 10, forming a sealed environment that effectively protects the antibodies inside and prevents evaporation. This sealed structure maintains the stability of the antibodies, ensuring the accuracy of experimental results. When the movable cover 22 is closed, it effectively prevents the entry of external air and impurities, while it can be easily opened when needed, facilitating antibody sampling, reagent addition, or observation of the experimental process. This allows researchers to flexibly control the experimental environment during antibody incubation experiments, meeting experimental requirements and improving operational convenience.
[0041] In this embodiment, when the movable cover 22 is closed over the bottom box assembly 10, the movable cover 22 is in a closed state, that is, the storable antibody incubation box 1 is in a closed state; when the movable cover 22 is open over the bottom box assembly 10, the movable cover 22 is in a closed-open state, that is, the storable antibody incubation box 1 is in an open state.
[0042] Specifically, the sealing cover 21, the movable cover 22, and the bottom box assembly 10 are connected as a whole. The sealing cover 21 is integrally formed on the bottom box assembly 10 and covers the bottom box assembly 10 to form a sealing part 101. The movable cover 22 is openably disposed above the bottom box assembly 10 and fits against the sealing cover 21 to form an opening part 102. That is, the sealing cover 21 is disposed on the sealing part 101, and the movable cover 22 is disposed on the opening part 102. When the antibody is stored in the storage cavity 11, when the storable antibody incubation box 1 is placed, the storable antibody incubation box 1 is configured to be housed in a box shell 80 with the sealing part 101 facing downwards. The sealing cover 21 and the bottom box assembly 10 are in a completely sealed state, so that the antibody will not overflow from the storage cavity 11. The storable antibody incubation box 1 housed in the casing 80 can be manufactured according to actual needs, and the size of the casing 80 is also manufactured according to the actual size of the storable antibody incubation box 1 to meet different usage requirements.
[0043] In the embodiments of this application, the closed portion 101 and the open portion 102 are connected as a whole to form the storable antibody incubation box 1. Preferably, the closed portion 101 and the open portion 102 each occupy half of the storable antibody incubation box 1, that is, the closed cover 21 and the movable cover 22 have the same area. Based on this, the amount of antibody stored in the storage cavity 11 is not greater than half the volume of the storage cavity 11, so that when the storable antibody incubation box 1 is set to be stored in the housing 80 with the closed portion 101 facing down, the antibody is completely stored in the closed portion 101, avoiding excessive antibody overflow into the open portion 102.
[0044] It is worth mentioning that the storable antibody incubation box 1 is configured with a preset shape. According to an embodiment of the present invention, the storable antibody incubation box 1 is configured as a cuboid. It is also worth noting that, according to other possible embodiments of the present invention, the storable antibody incubation box 1 can also be other shapes, which is not a limitation of the present invention. Preferably, in the embodiment of this application, the outer dimensions of the storable antibody incubation box 1 are set to 90mm × 60mm × 35mm. In other words, the length of the long side of the bottom box assembly 10 is set to 90mm, the length of the short side of the bottom box assembly 10 is set to 60mm, and the total height of the bottom box assembly 10 and the cover assembly 20 is set to 35mm. In other possible embodiments, the length of the long side of the bottom box assembly 10 can also be set to 80mm to 100mm, the length of the short side of the bottom box assembly 10 can also be set to 50mm to 70mm, and the total height of the bottom box assembly 10 and the cover assembly 20 can also be set to 25mm to 45mm. This is not a limitation of the present invention.
[0045] In the embodiments of this application, the storable antibody incubation box 1 is implemented as a transparent box, and the material of the storable antibody incubation box 1 is preferably made of plastic.
[0046] The sealing cover 21 includes an extension 213, three sealing edges 211, and a fitting edge 212. The sealing edges 211 are integrally connected to the upper end of the bottom box assembly 10 to fix the sealing cover 21 to the bottom box assembly 21. The fitting edge 212 is fitted to the movable cover 22. In other words, when the movable cover 22 is in the closed state, the sealing cover 21 and the movable cover 22 are fitted together to seal the storage cavity 11, so that the storage cavity 11 has good stability and airtightness, effectively protecting the antibody from leakage or evaporation. The extension 213 extends outward from the fitting edge 212. When the movable cover 22 is in the closed state, the side of the movable cover 22 near the fitting edge 212 is adapted to cover the extension 213, so that the gap between the closed cover 21 and the movable cover 22 is sealed by the extension 213, thereby ensuring that the antibody will not be lost and enhancing the sealing performance of the storable antibody incubation box 1. Specifically, the upper surface of the extension 213 is flush with the upper end of the bottom box assembly 10, so that when the side of the movable cover 22 near the fitting edge 212 covers the extension 213, the closed cover 21 and the movable cover 22 fit together without any height difference.
[0047] The movable cover 22 includes a cover portion 221 and an extension portion 222. The extension portion 222 is connected to the cover portion 221. Specifically, the extension portion 222 bends outward from the cover portion 221 to connect to the bottom box assembly 10, thereby stabilizing the movable cover 22 when it is in the closed state. The extension portion 222 has an inner surface 2221, which is adapted to fit against the outer surface of the bottom box assembly 10.
[0048] Specifically, the movable cover 22 further includes a first fixing component 223 and a second fixing component 224. The first fixing component 223 is disposed on the inner surface 2221 of the extension 222, and the second fixing component 224 is disposed on the outer surface of the base box assembly 10. The first fixing component 223 and the second fixing component 224 are adapted to be connected and fixed to each other, thereby fixing the movable cover 22 and the base box assembly 10 and ensuring the stability of the movable cover 22 when it is in the closed state. In the embodiments of this application, the first fixing component 223 and the second fixing component 224 are both configured as a snap-fit, so that the first fixing component 223 can be snapped onto the second fixing component 224. In other possible embodiments, the first fixing component 223 and the second fixing component 224 can be configured as two magnets for magnetic attraction, etc., which is not a limitation of this utility model.
[0049] More specifically, the cover portion 221 has a first side edge 2211, a second side edge 2212, an extension edge 2213, and a fixed edge 2214, wherein the fixed edge 2214 is integrally connected to the top of the bottom box assembly 10 to fix one side of the movable cover 22 to the bottom box assembly 10, and the extension edge 2213 is disposed between the cover portion 221 and the extension portion 222 to connect the cover portion 221 and the extension portion 222. The first side edge 2211 and the second side edge 2212 are the two sides of the cover portion 221, wherein the first side edge 2211 is adapted to fit against the fitting edge 212 of the closed cover 21, and the second side edge 2212 is adapted to fit against the top of the bottom box assembly 10. Thus, when the movable cover 22 is in the closed state, the closed cover 21 can seal the closed portion 101, and the movable cover 22 can seal the opening portion 102, so that the storage cavity 11 is in a sealed state to facilitate the storage of the antibody.
[0050] In summary, the storable antibody incubation box 1 can be directly used to store the antibody. After antibody incubation experiments, there is no need to re-store the antibody in centrifuge tubes, reducing the risk of antibody loss during transfer. In other words, the storable antibody incubation box 1 is equipped with a sealing cap 21 and a movable cap 22. The sealing portion 101 of the sealing cap 21 provides good sealing, which helps maintain the stability of the antibody and reduces the evaporation and spillage of the antibody. The opening portion 102 of the movable cap 22 can effectively prevent the entry of external air and impurities when closed, while it can be easily opened when needed, facilitating antibody sampling, reagent addition, or observation of the experimental process. This allows researchers to flexibly control the experimental environment during antibody incubation experiments, meeting experimental requirements and improving operational convenience.
[0051] As attached Figure 5 and Figure 6 This paper describes a storable antibody incubation box 1A provided in a second preferred embodiment of the present invention. The storable antibody incubation box 1A in this preferred embodiment is a variation of the first preferred embodiment described above.
[0052] Similarly, in this embodiment, the storable antibody incubation box 1 includes a base assembly 10 and a cover assembly 20. The cover assembly 20 is disposed above the base assembly 10, thereby providing support and fixation for the cover assembly 20. The base assembly 10 has a storage cavity 11, and the cover assembly 20 covers the base assembly 10 to seal the storage cavity 11. The antibody is suitable for storage within the storage cavity 11. The cover assembly 20 includes a closed cover 21 and a movable cover 22. The closed cover 21 is integrally formed on the base assembly 10 and covers the base assembly 10 to form a closed portion 101. The movable cover 22 is openably disposed above the base assembly 10 and fits against the closed cover 21 to form an open portion 102. When the storable antibody incubation box 1 is placed, the storable antibody incubation box 1 is arranged to be stored in a box shell 80 with the closed part 101 facing downwards, and the closed cover 21 and the bottom box assembly 10 are in a completely closed state, so that the antibody will not overflow from the storage cavity 11.
[0053] The closed cover 21 has three closed edges 211 and one fitting edge 212. The movable cover 22 includes a cover portion 221 and an extension portion 222. The extension portion 222 is connected to the cover portion 221. The cover portion 221 has a first side edge 2211, a second side edge 2212, an extended edge 2213, and a fixed edge 2214. The fixed edge 2214 is integrally connected to the top of the bottom box assembly 10 to fix one side of the movable cover 22 to the bottom box assembly 10. The extended edge 2213 is disposed between the cover portion 221 and the extension portion 222 to connect the cover portion 221 and the extension portion 222. The first side edge 2211 is adapted to fit against the fitting edge 212 of the closed cover 21, and the second side edge 2212 is adapted to fit against the top of the bottom box assembly 10.
[0054] In particular, in this embodiment, the storable antibody incubation box 1 further includes a sealing member 30, which is disposed on the movable cover 22. Specifically, the sealing member 30 is disposed on the inner surface of the movable cover 22 and surrounds the first side edge 2211, the second side edge 2212 and the extended edge 2213, which helps to improve the sealing performance of the storable antibody incubation box 1 and prevent antibody loss. In other words, when the movable cover 22 is in the closed state, the sealing member 30 is attached to the bottom box assembly 10. The sealing member 30 surrounds the first side edge 2211, the second side edge 2212 and the extended edge 2213, so that the gap between the first side edge 2211, the second side edge 2212 and the extended edge 2213 and the bottom box assembly 10 is completely sealed by the sealing member 30. Thus, when the antibody is stored in the storage cavity 11, it is in a completely sealed state, ensuring the airtightness of the storable antibody incubation box 1 and preventing antibody loss.
[0055] Those skilled in the art should understand that the embodiments of the present invention described above and shown in the accompanying drawings are merely examples and do not limit the present invention. The purpose of the present invention has been fully and effectively achieved. The functions and structural principles of the present invention have been shown and explained in the embodiments. Without departing from the stated principles, the implementation of the present invention may have any variations or modifications.
Claims
1. A storable antibody incubation kit, characterized in that, include: A base box assembly having a storage cavity; and A cover assembly is disposed above the base box assembly. The cover assembly includes a closed cover and a movable cover. The closed cover is integrally connected to the base box assembly. The movable cover is openably disposed above the base box assembly and fits against the closed cover. An antibody is suitable for storage in the storage cavity.
2. The storable antibody incubation box according to claim 1, wherein the storable antibody incubation box further comprises a sealing part and an opening part, the sealing cover is disposed in the sealing part, and the movable cover is disposed in the opening part.
3. The storable antibody incubation box according to claim 2, wherein when the antibody is stored in the storage cavity, the storable antibody incubation box is configured to be housed in a box shell with the closed portion facing downwards.
4. The storable antibody incubation box according to claim 3, wherein the sealing cover includes an extension, has three sealing edges and a fitting edge, the sealing edges are integrally connected to the upper end of the bottom box assembly to fix the sealing cover to the bottom box assembly, the fitting edge is adapted to fit against the movable cover, the extension extends outward from the fitting edge, and when the movable cover is in a closed state, the side of the movable cover near the fitting edge is adapted to cover the extension.
5. The storable antibody incubation box according to claim 4, wherein the movable cover includes a cover portion and an extension portion, the extension portion being bent outwardly from the cover portion to connect to the bottom box assembly, the extension portion having an inner surface, the inner surface of the extension portion being adapted to conform to the outer surface of the bottom box assembly.
6. The storable antibody incubation box according to claim 5, wherein the movable cover further includes a first fixing component and a second fixing component, the first fixing component being disposed on the inner surface of the extension, the second fixing component being disposed on the outer surface of the bottom box assembly, and the first fixing component and the second fixing component being adapted to be connected and fixed to each other.
7. The storable antibody incubation box according to claim 6, wherein the cover portion has a first side edge, a second side edge, an extended edge and a fixed edge, the fixed edge being connected above the bottom box assembly to fix one side of the movable cover to the bottom box assembly, the extended edge being disposed between the cover portion and the extended portion to connect the cover portion and the extended portion, the first side edge being adapted to fit against the fitting edge of the closed cover, and the second side edge being adapted to fit against the top of the bottom box assembly.
8. The storable antibody incubation box according to any one of claims 1 to 7, wherein the storable antibody incubation box further comprises a seal disposed on the movable cover.
9. The storable antibody incubation box according to any one of claims 1 to 7, wherein the length of the long side of the bottom box assembly is set to 80 mm to 100 mm, the length of the short side of the bottom box assembly is set to 50 mm to 70 mm, and the combined height of the bottom box assembly and the cover assembly is set to 25 mm to 45 mm.
10. The storable antibody incubation box according to any one of claims 1 to 7, wherein the amount of antibody stored in the storage chamber is not greater than half the volume of the storage chamber.