Medical intermediate halogenation reaction device convenient for purification

Abstract

The utility model relates to a reaction device, belongs to the technical field of medicinal material processing, and particularly relates to a pharmaceutical intermediate halogenation reaction device convenient for purification, which comprises an outer cylinder, a sealing bottom plate fixedly mounted on the bottom wall surface of the outer cylinder, a driving motor fixedly mounted on the top wall surface of the outer cylinder, and a reflux cylinder fixedly mounted on the inner side wall of the outer cylinder, a guide block is fixedly mounted on the inner side wall of the backflow cylinder, an inner cylinder is fixedly mounted on the bottom wall surface of the guide block, a spiral blade is arranged in the inner cylinder, a plurality of communicating grooves are formed in the top end of the inner side wall of the sealing bottom plate, and a plurality of backflow grooves are formed in the top wall surface of the backflow cylinder; according to the device, medicinal materials are stirred and conveyed through the spiral blades, the medicinal materials are extruded through continuous conveying of the spiral blades, then the medicinal materials flow back to the interior of the guide block through the backflow groove, the medicinal materials are stirred and mixed again through the spiral blades, the stirring effect on the medicinal materials is improved, and the medicinal materials can fully react; the problem that an existing reaction device is poor in stirring effect is solved.

Description

TECHNICAL FIELD

[0001] The utility model relates to medicinal material processing technical field, especially a medical intermediate halogenation reaction device convenient to purify. BACKGROUND

[0002] The medical intermediate is actually some chemical raw materials or chemical products used in the synthesis process of medicines. Such chemical products do not require a production license for medicines and can be produced in ordinary chemical plants. As long as a certain level is reached, it can be used for the synthesis of medicines.

[0003] According to the search, the patent with the publication number CN219308724U discloses a reaction device for medical intermediate production, which comprises a reaction kettle and two supporting legs fixedly arranged on the bottom surface of the reaction kettle. The inside of the reaction kettle is provided with a blocking prevention mechanism and a stirring mechanism. The blocking prevention mechanism can rotate the rotating blade inside the feeding pipe when the raw materials enter the inside of the reaction kettle, so that the raw materials cannot be blocked inside the feeding pipe. During the discharging process, the blocking pipe can rotate inside the discharging pipe to avoid blocking the raw materials inside the discharging pipe during the discharging process. The closing part can close the feeding pipe during the reaction of the raw materials to prevent external objects from entering the inside of the reaction kettle, resulting in poor reaction effect. The stirring mechanism can make the stirring rod rotate inside the reaction kettle to stir and mix the raw materials inside the reaction kettle, so that the reaction effect is better.

[0004] In the above-mentioned prior art, the stirring mechanism can make the stirring rod rotate inside the reaction kettle to stir and mix the raw materials inside the reaction kettle, so that the reaction effect is better. However, in actual use, the stirring rod is driven to rotate by the motor to stir the medicinal materials. The single set of stirring blades can only stir within a certain range, and it is difficult to cover every corner and edge position of the reaction kettle, so the stirring effect is poor. UTILITY MODEL CONTENTS

[0005] In order to solve the above technical problems, the utility model provides a medical intermediate halogenation reaction device convenient to purify. The medicinal materials are stirred and conveyed by the spiral blade. The continuous conveying of the spiral blade will extrude the medicinal materials, and then the spiral blade will re-stir and mix the medicinal materials through the reflux tank. The stirring effect of the medicinal materials is improved, and the medicinal materials can fully react.

[0006] The technical solution for achieving the object of the utility model is as follows: a medical intermediate halogenation reaction device convenient to purify, which comprises an outer cylinder, a sealing bottom plate is fixedly installed on the bottom wall surface of the outer cylinder, a driving motor is fixedly installed on the top wall surface of the outer cylinder, a driving shaft inside the outer cylinder is fixedly installed on the output end of the driving motor, a reflux cylinder is fixedly installed on the inner side wall of the outer cylinder, a guide block is fixedly installed on the inner side wall of the reflux cylinder, an inner cylinder is fixedly installed on the bottom wall surface of the guide block, the bottom end of the inner cylinder is fixedly installed on the top wall surface of the sealing bottom plate, a spiral blade is arranged in the inner cylinder, the spiral blade is fixedly installed on the side wall bottom end of the driving shaft, a plurality of communication grooves are formed in the inner side wall top end of the sealing bottom plate in a circumferential equidistant distribution mode, a plurality of reflux grooves are formed in the top wall surface of the reflux cylinder, and the plurality of reflux grooves are respectively aligned with the adjacent communication grooves.

[0007] In some embodiments, the inner side wall of the guide block is inclined, and a plurality of stirring rods are fixedly installed on the side wall top end of the driving shaft.

[0008] In some embodiments, the inner side wall of the sealing bottom plate is fixedly installed with a discharging plate, the top wall surface of the discharging plate is recessed and inclined, and the inner side wall of the discharging plate is fixedly installed with a discharging valve.

[0009] In some embodiments, heating wires are arranged in the inner side wall of the outer cylinder and are sleeved on the side wall of the inner cylinder.

[0010] In some embodiments, a plurality of feeding cylinders are fixedly installed on the top wall surface of the outer cylinder and are in communication with the inner part of the outer cylinder, and a plurality of supporting legs are fixedly installed on the bottom wall surface of the sealing bottom plate.

[0011] Compared with the prior art, the utility model has the following advantages:

[0012] Firstly, the utility model discloses the following: the medicinal materials to be processed are poured into the inner part of the outer cylinder through the feeding cylinder, the medicinal materials fall into the inner part of the inner cylinder under the guidance of the guide block, then the medicinal materials are stirred and conveyed through the spiral blade, since there is no gap between the inner side wall of the inner cylinder and the spiral blade, when the medicinal materials fall into the inner part of the sealing bottom plate, the continuous conveying of the spiral blade can extrude the medicinal materials, so that the medicinal materials enter the inner part of the communication grooves and the reflux grooves, then the medicinal materials are refluxed into the inner part of the guide block through the reflux grooves, the spiral blade can stir and mix the medicinal materials again, the medicinal materials can be fully reacted by repeatedly flowing in the inner part of the outer cylinder, and the stirring effect of the medicinal materials is improved.

[0013] Secondly, the utility model discloses the following: the inner side wall of the guide block is inclined, the medicinal materials are guided, the medicinal materials in the inner part of the guide block are stirred through the stirring rods, the medicinal materials are mixed, and the medicinal materials are uniformly distributed in the inner part of the guide block, so that the medicinal materials can fall into the inner part of the inner cylinder conveniently. BRIEF DESCRIPTION OF DRAWINGS

[0014] The utility model is further explained below in combination with the drawings and embodiments:

[0015] Figure 1 The utility model discloses a medical intermediate halogenation reaction device convenient to purify whole structure schematic diagram;

[0016] Figure 2 The utility model discloses the internal structure schematic diagram of outer tube;

[0017] Figure 3 The utility model discloses the whole structure schematic diagram of inner tube;

[0018] Figure 4 The utility model discloses the whole structure schematic diagram of outer tube.

[0019] Mark explanation:

[0020] 1, outer tube, 2, support leg, 3, feed cylinder, 4, drive motor, 5, drive shaft, 6, guide block, 7, inner tube, 8, spiral blade, 9, stirring rod, 10, sealing bottom plate, 11, communication groove, 12, reflux cylinder, 13, reflux groove, 14, discharge plate, 15, discharge valve, 16, heating wire. Specific implementation

[0021] The utility model is described in detail below, and the technical scheme in the embodiment of the utility model is clearly and completely described. Obviously, the described embodiment is only a part of the embodiment of the utility model, not all the embodiments. Based on the embodiment in the utility model, all other embodiments obtained by the person skilled in the art without creative labor belong to the scope of the utility model protection.

[0022] The utility model discloses a medical intermediate halogenation reaction device convenient to purify through improvement, and the technical scheme of the utility model is:

[0023] As Figures 1-4As shown in the figure, a medical intermediate halogenation reaction device convenient for purification comprises an outer cylinder 1, a sealing bottom plate 10 fixedly installed on the bottom wall surface of the outer cylinder 1, a plurality of feeding cylinders 3 fixedly installed on the top wall surface of the outer cylinder 1 and communicating with the inside of the outer cylinder 1, a driving motor 4 fixedly installed on the top wall surface of the outer cylinder 1, a driving shaft 5 fixedly installed on the output end of the driving motor 4 and located in the inside of the outer cylinder 1, a reflux cylinder 12 fixedly installed on the inner side wall of the outer cylinder 1, a guide block 6 fixedly installed on the inner side wall of the reflux cylinder 12, an inner cylinder 7 fixedly installed on the bottom wall surface of the sealing bottom plate 10 and at the top wall surface of the sealing bottom plate 10, a plurality of spiral leaves 8 arranged in the inside of the inner cylinder 7 and fixedly installed on the side wall bottom end of the driving shaft 5, a plurality of communication grooves 11 circumferentially and equidistantly arranged at the top end of the inner side wall of the sealing bottom plate 10, a plurality of reflux grooves 13 arranged at the top wall surface of the reflux cylinder 12 and respectively aligned with the adjacent communication grooves 11; the medicinal materials to be processed are poured into the inside of the outer cylinder 1 through the feeding cylinders 3, the medicinal materials fall into the inside of the inner cylinder 7 under the guidance of the guide block 6, and then the medicinal materials are stirred and conveyed by the spiral leaves 8, since there is no gap between the spiral leaves 8 and the inner side wall of the inner cylinder 7, when the medicinal materials fall into the inside of the sealing bottom plate 10, the continuous conveying of the spiral leaves 8 will extrude the medicinal materials, so that the medicinal materials enter the inside of the communication grooves 11 and the reflux grooves 13, and then the medicinal materials flow back to the inside of the guide block 6 through the reflux grooves 13, so that the spiral leaves 8 re-stir and mix the medicinal materials, by repeatedly flowing of the medicinal materials in the inside of the outer cylinder 1, the stirring effect of the medicinal materials is improved, and the medicinal materials can fully react.

[0024] As Figures 2-4 shown in the figure, in an embodiment, in order to facilitate the medicinal materials to fall into the inside of the inner cylinder 7, the inner side wall of the guide block 6 is inclined; by setting the inner side wall of the guide block 6 to be inclined, the medicinal materials are guided, so that the medicinal materials can conveniently fall into the inside of the inner cylinder 7; a plurality of stirring rods 9 are fixedly installed on the side wall top end of the driving shaft 5; the medicinal materials in the inside of the guide block 6 are stirred by the stirring rods 9, so that the medicinal materials are mixed and uniformly distributed in the inside of the guide block 6.

[0025] As Figures 2-4As shown, in an embodiment, in order to facilitate the discharge of medicinal materials, the inner side wall of the sealing bottom plate 10 is fixedly installed with a discharge plate 14, the top wall surface of the discharge plate 14 is recessed and inclined, and the inner side wall of the discharge plate 14 is fixedly installed with a discharge valve 15; by opening the discharge valve 15, when the spiral blade 8 pushes the medicinal materials downward, the medicinal materials will be discharged outward through the discharge valve 15 under the guidance of the discharge plate 14; the inner part of the outer cylinder 1 is provided with a heating wire 16, and the heating wire 16 is sleeved on the side wall of the inner cylinder 7; by sleeving the heating wire 16 on the side wall of the inner cylinder 7, the heating wire 16 can heat the medicinal materials in the inner cylinder 7, and the medicinal materials are divided into two parts through the communication groove 11 and the reflux groove 13, so that the heating wire 16 can uniformly heat the medicinal materials, and the reaction effect of the medicinal materials is ensured; a plurality of supporting legs 2 are fixedly installed on the bottom wall surface of the sealing bottom plate 10; the device is supported by the supporting legs 2, so that there is enough gap between the bottom of the sealing bottom plate 10 and the ground for discharging.

[0026] The specific working method is: the medicinal materials to be processed are poured into the inner part of the outer cylinder 1 through the feeding cylinder 3, the medicinal materials fall into the inner part of the inner cylinder 7 under the guidance of the guide block 6, and then the medicinal materials are stirred and conveyed by the spiral blade 8; since there is no gap between the spiral blade 8 and the inner side wall of the inner cylinder 7, when the medicinal materials fall into the inner part of the sealing bottom plate 10, the continuous conveying of the spiral blade 8 will extrude the medicinal materials, so that the medicinal materials enter the inner part of the communication groove 11 and the reflux groove 13, and then flow back to the inner part of the guide block 6 through the reflux groove 13, so that the spiral blade 8 re-stirs and mixes the medicinal materials, the stirring effect of the medicinal materials is improved by repeatedly flowing in the inner part of the outer cylinder 1, the medicinal materials can fully react, and after the reaction is completed, the discharge valve 15 is opened, and when the spiral blade 8 pushes the medicinal materials downward, the medicinal materials will be discharged outward through the discharge valve 15 under the guidance of the discharge plate 14.

[0027] The technical means disclosed in the utility model scheme is not limited to the technical means disclosed in the above technical means, and also includes technical solutions composed of equivalent replacement of the above technical features. The unfinished matters of the utility model belong to the common knowledge of those skilled in the art.

Claims

1. A halogenation reaction apparatus for facilitating the purification of pharmaceutical intermediates, comprising an outer cylinder (1), wherein a sealing base plate (10) is fixedly installed on the bottom wall of the outer cylinder (1), characterized in that: A drive motor (4) is fixedly installed on the top wall of the outer cylinder (1). A drive shaft (5) located inside the outer cylinder (1) is fixedly installed at the output end of the drive motor (4). A return cylinder (12) is fixedly installed on the inner side wall of the outer cylinder (1). A guide block (6) is fixedly installed on the inner side wall of the return cylinder (12). An inner cylinder (7) is fixedly installed on the bottom wall of the guide block (6). The bottom end of the inner cylinder (7) is fixedly installed on the top wall of the sealing base plate (10). A spiral blade (8) is provided inside the inner cylinder (7). The spiral blade (8) is fixedly installed on the bottom end of the side wall of the drive shaft (5). A plurality of circumferentially distributed connecting grooves (11) are opened at the top of the inner side wall of the sealing base plate (10). A plurality of return grooves (13) are opened on the top wall of the return cylinder (12). The plurality of return grooves (13) are respectively aligned with the adjacent connecting grooves (11).

2. The apparatus for halogenation reaction of pharmaceutical intermediates for easy purification according to claim 1, characterized in that: The inner wall of the guide block (6) is inclined, and multiple stirring rods (9) are fixedly installed on the top of the side wall of the drive shaft (5).

3. The apparatus for halogenation reaction of pharmaceutical intermediates for easy purification according to claim 1, characterized in that: The inner wall of the sealing base plate (10) is fixedly installed with a discharge plate (14), the top wall of the discharge plate (14) is recessed and inclined, and the inner wall of the discharge plate (14) is fixedly installed with a discharge valve (15).

4. The apparatus for halogenation reaction of pharmaceutical intermediates for easy purification according to claim 1, characterized in that: The outer cylinder (1) is provided with a heating wire (16) inside, and the heating wire (16) is sleeved on the side wall of the inner cylinder (7).

5. The apparatus for halogenation reaction of pharmaceutical intermediates for easy purification according to claim 1, characterized in that: The top wall of the outer cylinder (1) is fixedly installed with multiple feed cylinders (3) that communicate with the inside of the outer cylinder (1), and the bottom wall of the sealing base plate (10) is fixedly installed with multiple support legs (2).

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