Mask with built-in nasal cavity sustained-release administration capsule

Abstract

The utility model discloses a mask with a built-in nasal cavity sustained-release drug delivery capsule. The mask comprises a mask body, ear hanging parts and a drug sustained-release capsule, the number of the ear hanging parts is two, and the two ear hanging parts are fixedly installed on the two sides of the mask body respectively. The number of the medicine sustained-release capsules is two, the two medicine sustained-release capsules are arranged side by side in a spaced mode, and the two medicine sustained-release capsules are both fixedly installed on the inner surface of the mask body. Wherein the medicine sustained-release capsule extends into the nasal cavity, and an air inlet interval is arranged between the outer wall of the medicine sustained-release capsule and the inner wall of the nasal cavity. When a user wears the mask, medicine can be continuously and accurately released, the treatment effect is improved, unnecessary medicine waste is reduced, and the mask is convenient and easy to use.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical equipment technical field especially is related to a mask of built -in nasal cavity slow -release medicine capsule. BACKGROUND

[0002] With the development of modern medical technology, nasal cavity drug delivery system has been widely used in the treatment of various diseases due to its rapid absorption and high efficiency. However, the traditional nasal cavity drug delivery method, such as nasal drops and nasal spray, can meet the demand of rapid absorption to some extent, but it has obvious shortcomings in the control of drug composition release, long-term effect maintenance and precise drug delivery for complex traditional Chinese medicine composition. The traditional single particle nasal cavity slow-release system cannot realize the precise release of complex traditional Chinese medicine composition. In addition, the existing nasal cavity slow-release device also has obvious shortcomings in the long-term absorption of traditional Chinese medicine composition and the maintenance of drug efficacy, which reduces the treatment effect.

[0003] Therefore, a mask of built-in nasal cavity slow-release medicine capsule is provided. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a mask of built-in nasal cavity slow-release medicine capsule, which aims to solve or improve at least one of the above technical problems.

[0005] To achieve the above-mentioned purpose, the utility model provides the following scheme: the utility model provides a mask of built-in nasal cavity slow-release medicine capsule, which comprises:

[0006] A mask body;

[0007] Two ear hanging parts are arranged on both sides of the mask body;

[0008] Two medicine slow-release capsules are arranged side by side and spaced apart, and both of the medicine slow-release capsules are fixedly installed on the inner surface of the mask body;

[0009] The medicine slow-release capsule extends into the nasal cavity, and the outer wall of the medicine slow-release capsule and the inner wall of the nasal cavity are provided with an air inlet interval.

[0010] According to the mask of built-in nasal cavity slow-release medicine capsule, the medicine slow-release capsule is provided with a porous medicine-soaked sponge, and the porous medicine-soaked sponge is in contact with the inner wall of the nasal cavity.

[0011] According to the mask of built-in nasal cavity slow-release medicine capsule, the inner surface of the mask body is provided with a medicine slow-release patch.

[0012] The nose-adapting metal strip is arranged on the top of the mask body.

[0013] The medicine release capsule is arranged obliquely, and one end of the medicine release capsule close to the mask body is lower than the other end.

[0014] The outer diameter of the medicine release capsule is 4mm-6mm.

[0015] The shape of the medicine release patch includes but is not limited to strip, circle, ellipse and polygon.

[0016] The utility model discloses the following technical effects:

[0017] The utility model discloses a kind of built-in nasal cavity sustained-release drug delivery capsule's mask, and the mask body is worn on face by hanging ear part, adjust position to make two medicine release capsules be placed into two nasal cavities, different medicine components are filled in capsule according to treatment demand by medicine release capsule, accurate release of drug is realized, ensure that drug is placed in nasal cavity, according to predetermined time point and rate of release, accurate release of drug is realized, so as to improve treatment effect, reduce unnecessary drug waste.

[0018] The utility model discloses a kind of built-in nasal cavity sustained-release drug delivery capsule's mask, and the mask body is worn on face by hanging ear part, adjust position to make two medicine release capsules be placed into two nasal cavities, different medicine components are filled in capsule according to treatment demand by medicine release capsule, accurate release of drug is realized, ensure that drug is placed in nasal cavity, according to predetermined time point and rate of release, accurate release of drug is realized, so as to improve treatment effect, reduce unnecessary drug waste.

[0019] The utility model discloses a kind of built-in nasal cavity sustained-release drug delivery capsule's mask, and the mask body is worn on face by hanging ear part, adjust position to make two medicine release capsules be placed into two nasal cavities, different medicine components are filled in capsule according to treatment demand by medicine release capsule, accurate release of drug is realized, ensure that drug is placed in nasal cavity, according to predetermined time point and rate of release, accurate release of drug is realized, so as to improve treatment effect, reduce unnecessary drug waste. BRIEF DESCRIPTION OF DRAWINGS

[0020] In order to more clearly illustrate the technical scheme in the embodiment of the utility model or prior art, the following will briefly introduce the drawing needed to be used in the embodiment, obviously, the drawing in the following description only some embodiments of the utility model, for those skilled in the art, under the premise of not paying creative labor, other drawings can also be obtained according to these drawings.

[0021] Fig. 1 It is the front view of the utility model;

[0022] Fig. 2 It is the rear view of the utility model;

[0023] Fig. 3 It is a schematic view of the medicine sustained-release capsule inserted into the nasal cavity in the utility model.

[0024] Among them, 1, mask body; 2, ear hook part; 3, medicine sustained-release capsule; 4, porous medicine-soaked sponge; 5, medicine sustained-release patch; 6, nose part adhering metal strip. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor belong to the protection scope of the utility model.

[0026] In order to make the above-mentioned purposes, features and advantages of the utility model more obvious and easy to understand, the utility model will be further described in detail below with reference to the drawings and specific embodiments.

[0027] Referring to Figs. 1-3 The utility model provides a kind of mask of built-in nasal cavity sustained-release drug delivery capsule, comprising:

[0028] Mask body 1;

[0029] Ear hook part 2, two ear hook parts 2 are equipped, and two ear hook parts 2 are respectively fixedly installed on the two sides of mask body 1;

[0030] Medicine sustained-release capsule 3, two medicine sustained-release capsules 3 are equipped, and two medicine sustained-release capsules 3 are arranged in parallel and interval, and two medicine sustained-release capsules 3 are all fixedly installed on the inner surface of mask body 1;

[0031] Among them, medicine sustained-release capsule 3 extends into nasal cavity, and air inlet interval is equipped between the outer wall of medicine sustained-release capsule 3 and the inner wall of nasal cavity.

[0032] By doing so, the patient of the utility model wears mask body 1 on face by ear hook part 2, adjusts position to make two medicine sustained-release capsules 3 be placed into two nasal cavities, fills different medicine components in capsule according to treatment demand by medicine sustained-release capsule 3, realizes the accurate release of medicine, ensures that medicine is released according to predetermined time point and rate after being placed into nasal cavity, realizes the accurate release of medicine, thereby improves treatment effect, reduces unnecessary medicine waste;

[0033] The utility model discloses a drug sustained release capsule 3 is fixedly installed on the inner surface of the mask body 1, not only convenient for patient to use, can improve the comfort of patient, and can realize the sustained release of drug while wearing the mask of patient, convenient and easy to use.

[0034] The utility model discloses a drug sustained release capsule 3 is fixedly installed on the inner surface of the mask body 1, not only convenient for patient to use, can improve the comfort of patient, and can realize the sustained release of drug while wearing the mask of patient, convenient and easy to use.

[0035] Further optimization scheme, drug sustained release capsule 3 adopt multiple nano and micron particle stratification design, drug sustained release capsule 3 include the first layer, second layer and third layer that set gradually from outside to inside,

[0036] The first layer is a liposome nanoparticle with a particle size of 200-300 nm, and the liposome nanoparticle encapsulates anti-inflammatory traditional Chinese medicine ingredients (such as forsythia suspensa and scutellaria baicalensis); the liposome has good compatibility with the nasal mucosa, is suitable for rapid absorption, and can quickly relieve nasal inflammation; the liposome is hydrophobic and has affinity with the mucosa, is quickly released after entering the nasal cavity, and has a controlled release time of 0-2 hours.

[0037] The second layer is a chitosan micron particle with a particle size of 2-5 μm, and the chitosan micron particle encapsulates anti-allergic traditional Chinese medicine ingredients (such as xanthium sibiricum and atractylodes macrocephala); the sustained release property of chitosan helps long-acting release of the medicine and maintains sustained anti-allergic effect; the chitosan is slowly degraded in the nasal cavity, has a controlled release time of 4-8 hours, and is suitable for long-term maintenance of drug efficacy.

[0038] The third layer is a PLGA microsphere nanoparticle with a particle size of 0.5-1 μm, and the PLGA microsphere nanoparticle encapsulates volatile traditional Chinese medicine ingredients (such as mentha and borneol); the PLGA microsphere nanoparticle is used to keep the nasal cavity cool and expand the respiratory tract; the PLGA has strong sustained release property, is suitable for long-term release, has a controlled release time of 8-12 hours, and keeps the cooling effect lasting.

[0039] Through the multi-layer particle distribution, the liposome nanoparticle has good affinity with the nasal mucosa, is suitable for rapid release of forsythia suspensa or scutellaria baicalensis ingredients, the adhesion of the chitosan micron particle improves the retention effect of the medicine, is suitable for long-acting anti-allergic traditional Chinese medicine ingredients, the PLGA microsphere nanoparticle is used for long-term sustained release of volatile traditional Chinese medicine ingredients, ensures sustained release within 12 hours, and gradually releases different levels of medicine by responding to the humidity and temperature in the nasal cavity.

[0040] Further optimization scheme, drug sustained release capsule 3 outer cover is equipped with porous medicine-soaked sponge 4, and the porous medicine-soaked sponge 4 contacts the inner wall of the nasal cavity.

[0041] The porous drug-soaked sponge 4 is made of biocompatible materials such as gelatin and sodium alginate, ensuring that the material is non-irritating and biodegradable in the nasal cavity; the porous drug-soaked sponge 4 has a layered porous structure, with different layers having different pore sizes, allowing different particles to be embedded in specific pore layers to ensure that different types of particles release drugs within their respective time periods; the sponge capsule structure is soft and adapts to the shape of the inner wall of the nasal cavity, avoiding respiratory tract obstruction and ensuring comfort; the layered porous structure of the porous drug-soaked sponge 4 is used to control the release of each particle at different stages, and the sponge carrier material is selected from gelatin, sodium alginate, or a combination thereof.

[0042] Further optimization, the inner surface of the mask body 1 is provided with a drug sustained-release patch 5, which can assist in slow-release drug delivery and provide multiple drug delivery paths.

[0043] Further optimization, the top of the mask body 1 is provided with a nose-fitting metal strip 6, which facilitates adjustment of the wearing position of the mask body 1 and realizes fitting to the nose.

[0044] Further optimization, the drug sustained-release capsule 3 is inclined and arranged, and the end of the drug sustained-release capsule 3 close to the mask body 1 is lower than the other end, realizing the drug sustained-release capsule 3.

[0045] Further optimization, the outer diameter of the drug sustained-release capsule 3 is 4mm-6mm.

[0046] Further optimization, the shape of the drug sustained-release patch 5 includes but is not limited to strip-shaped, circular, oval, and polygonal.

[0047] The drugs that can be used for nasal administration include local treatment drugs and systemic administration drugs. Local treatment drugs are mainly used for treating local ailments, such as drugs for reducing congestion and steroid anti-inflammatory drugs. Systemic administration drugs include protein / polypeptide drugs and small molecule drugs, such as insulin, oxytocin, vasopressin, etc. In addition, nasal administration is also used for the administration of vaccines, such as respiratory syncytial virus and influenza virus vaccines, etc.

[0048] The dosage forms for nasal administration mainly include nose drops, sprays, films, powders, gel preparations, microsphere preparations, cyclodextrin inclusions, aerosols, dry powders, liposomes, etc. Among them, nose drops, sprays, powders, and dry powders are relatively common dosage forms.

[0049] Nasal administration has a wide range of applications and can be used to treat a variety of diseases, including but not limited to rhinitis, colds, local infections, sinusitis, brain diseases, and systemic diseases such as diabetes, respiratory diseases, etc. The advantages of nasal administration are rapid absorption, high bioavailability, small side effects, and the ability to bypass important barriers for certain drugs, such as the blood-brain barrier. Compared with traditional nasal sprays, nasal powders have the advantages of high stability, long shelf life, and precise dosage.

[0050] The main nasal cavity powder types include vaccine powder, anti-allergic powder, analgesic and antidepressant drug powder, antibacterial and antiviral powder, endocrine regulation powder, etc.; the main treatment diseases include allergic diseases, infectious diseases, nervous system diseases, endocrine diseases, and are used for preventive vaccination, first aid and emergency treatment.

[0051] In the description of the utility model, it is understood that the orientation or position relation indicated by the terms "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like is the orientation or position relation shown in the drawings, and is only for the convenience of describing the utility model, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the utility model.

[0052] Obviously, the above embodiments of the utility model are only examples for clearly illustrating the utility model, and are not a limitation on the embodiments of the utility model. On the basis of the above description, other different forms of changes or changes can be made by the ordinary skilled user in the art. Here, it is not necessary and impossible to enumerate all the embodiments. Any modification, equivalent replacement and improvement made within the spirit and principle of the utility model should be included in the protection scope of the utility model claims.

Claims

1. A mask for an in-nose sustained release drug delivery capsule, characterized in that, Include: Mask body (1); Ears (2), the ear (2) is provided with two, two said ear (2) is respectively fixedly installed on both sides of the mask body (1); Drug sustained-release capsules (3), the drug sustained-release capsules (3) are provided with two, two said drug sustained-release capsules (3) are arranged side by side and are spaced, and two said drug sustained-release capsules (3) are fixedly installed on the inner surface of the mask body (1); Wherein, the drug sustained-release capsules (3) extend into the nasal cavity, and the outer wall of the drug sustained-release capsules (3) and the inner wall of the nasal cavity are provided with air inlet intervals.

2. The mask for the built-in intranasal sustained-release administration capsule according to claim 1, characterized by: The drug sustained-release capsules (3) are provided with porous medicine-soaked sponges (4), which are in contact with the inner wall of the nasal cavity.

3. The mask for the built-in intranasal sustained-release administration capsule according to claim 1, characterized by: The inner surface of the mask body (1) is provided with a drug sustained-release patch (5).

4. The mask for the in-built intranasal sustained release drug delivery capsule as claimed in claim 1 wherein: The top of the mask body (1) is provided with a nose fitting metal strip (6).

5. The mask for the in-built intranasal sustained release drug delivery capsule as claimed in claim 1 wherein: The drug sustained-release capsules (3) are arranged obliquely, and the end of the drug sustained-release capsules (3) close to the mask body (1) is lower than the other end.

6. The mask for the in-nose slow release drug delivery capsule according to claim 1, wherein: The outer diameter of the drug sustained-release capsules (3) is 4mm-6mm.

7. The mask for the in-nose slow release drug delivery capsule according to claim 3, wherein: The shape of the drug sustained-release patch (5) includes but is not limited to strip, circle, ellipse and polygon.

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