Contrast color card for judging mammalian blood sample freshness
By designing a contrast color card containing multiple sector-shaped contrast color samples and a protective plate assembly, the freshness of blood samples can be quickly determined, solving the problem of inconvenient blood sample freshness determination in existing technologies, reducing experimental costs, and improving the effect of DNA extraction.
Patent Information
- Application Number
- CN202422873842.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-22
- Publication Date
- 2025-11-28
- Estimated Expiration
- 2034-11-22
AI Technical Summary
Current technology lacks convenient methods to determine the freshness of blood samples, resulting in poor DNA extraction results and increased experimental costs.
Design a colorimetric card containing multiple sector-shaped color samples to represent the color of blood at different storage times. It consists of a colorimetric card component and a protective plate component, and is used to quickly determine the freshness of blood samples. The components include a protective plate component and a colorimetric card component.
It enables rapid and accurate determination of blood sample freshness, simplifies operations, reduces unnecessary experimental costs, and improves DNA extraction efficiency.
Smart Images

Figure CN223611380U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to experimental analysis instrument technical field, concretely is a contrast color card of judging mammal blood sample fresh degree. BACKGROUND
[0002] Genetic research cannot be separated from the support of biological technology. DNA, as one of the basic units of genetic information, is an important object of genetic research, so genetic research needs a large amount of high-quality DNA as the research basis. In order to have enough statistical research on the diversity of genetics and the correlation between traits, a large DNA library needs to be established.
[0003] Blood samples are usually the preferred material for DNA extraction because they have mature DNA extraction methods and high-throughput DNA extraction techniques, high yield and good quality. However, high-throughput DNA extraction and centralized analysis rely on fresh blood, but the transportation and storage of blood samples may lead to a decrease in the freshness of the blood sample, further leading to low DNA yield and poor quality. If the freshness of the sample blood can be known before DNA extraction, the extraction effect can be expected before DNA extraction, and unnecessary experimental costs can be reduced by avoiding using non-fresh blood as a sample.
[0004] However, there is currently no related analysis tool, especially a portable and simple-to-operate test paper or colorimetric card technology, so there is an urgent need for a convenient method to distinguish the freshness of blood samples.
[0005] Based on this, the utility model is proposed. UTILITY MODEL CONTENT
[0006] The utility model aims at providing a contrast color card for judging the freshness of mammal blood samples, which can quickly judge the freshness of mammal blood samples, and thus facilitate the selection of suitable DNA extraction blood samples by operators.
[0007] In order to achieve the above-mentioned purpose, the utility model provides the following technical scheme:
[0008] A contrast color card for judging the freshness of mammal blood samples, comprising a guard plate assembly and a color card assembly;
[0009] The guard plate assembly has a circular structure, comprising a color card front guard plate and a color card rear guard plate; the color card assembly is arranged between the color card front guard plate and the color card rear guard plate;
[0010] The color card assembly comprises a plurality of contrast color samples, each contrast color sample has a fan-shaped structure, is arranged above the color card rear guard plate, and is uniformly distributed with the center line of the color card rear guard plate as the center, and the colors of each contrast color sample are different;
[0011] The contrast color sample is further provided with a contrast color card slot for accommodating the contrast object;
[0012] The color card front guard plate is provided with an observation opening for observing and contrasting the contrast object and the contrast color sample.
[0013] Further, the color card assembly comprises at least six contrast color samples, and the colors of the contrast color samples are the colors of blood samples in different time periods.
[0014] Further, the materials of the contrast color samples in the color card assembly are the same.
[0015] Further, the contrast color sample is movably connected with the color card rear guard plate.
[0016] Further, the centers of the color card front guard plate and the color card rear guard plate are penetrated by rivets from top to bottom, the contrast color sample is fixed between the color card front guard plate and the color card rear guard plate through the rivets, and the contrast color sample is rotated around the rivets during use.
[0017] Further, the color card assembly further comprises a dial piece arranged at the arc-shaped edge of the contrast color sample, and the dial piece is used for rotating the contrast color sample to the position of the observation opening of the color card front guard plate.
[0018] Further, the observation opening part of the color card front guard plate is in an open structure, and is used for directly observing the contrast color sample and the contrast object at the position.
[0019] The embodiment of the utility model has the advantages of:
[0020] The utility model discloses a contrast color card for judging the freshness degree of mammal blood sample, which mainly comprises a guard plate assembly and a color card assembly, wherein the color card assembly is arranged in the inner cavity of the shell formed by the guard plate assembly, the color card assembly comprises contrast color samples corresponding to the colors of blood samples stored for different time periods, the storage time of the blood sample to be measured can be quickly judged by comparing the color of the contrast color sample with the blood sample to be measured, so that the freshness degree of the blood sample can be quickly and accurately judged by the experimenters. DRAWINGS
[0021] In order to more clearly illustrate the technical scheme of the embodiment of the utility model, the following will briefly introduce the drawings needed to be used in the embodiment, and it should be understood that the following drawings only show some embodiments of the utility model, and should not be regarded as the limitation to the scope, and for the ordinary skilled in the art, other related drawings can be obtained without the creative labor on the premise of the drawings.
[0022] Figure 1 It is the overall front view of the utility model;
[0023] Figure 2 It is the whole main view internal structure schematic diagram of the utility model;
[0024] Figure 3 It is the whole right view of the utility model;
[0025] Reference signs: 1-protecting plate assembly;101-protecting plate in front of color card;102-protecting plate behind color card;2-color card assembly;201-rivets;202-pieces;203-color card slot;3-color card;301-1st contrast color sample;302-2nd contrast color sample;303-3rd contrast color sample;304-4th contrast color sample;305-5th contrast color sample;306-6th contrast color sample. DETAILED DESCRIPTION
[0026] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the technical scheme in the embodiments of the utility model will be described clearly and completely below in combination with the drawings in the embodiments of the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, rather than all the embodiments. The components of the embodiments of the utility model described and shown in the drawings can be arranged and designed in various different configurations.
[0027] Therefore, the following detailed description of the embodiments of the utility model provided in the drawings is not intended to limit the scope of the claimed utility model, but only represents selected embodiments of the utility model. Based on the embodiments in the utility model, all other embodiments obtained by those of ordinary skill in the art without creative labor fall within the scope of protection of the utility model.
[0028] It should be noted that: similar signs and letters represent similar items in the following drawings, so once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings.
[0029] In the description of the utility model, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship commonly placed when the utility model product is used, which is only for the convenience of describing the utility model and simplifying the description, and does not indicate or imply that the indicated device or element must have a particular orientation, be constructed and operated in a particular orientation, therefore it cannot be understood as a limitation on the utility model. In addition, the terms "first", "second", "third" and the like are only used for differentiation in description, and cannot be understood as indicating or implying relative importance.
[0030] In addition, the terms "horizontal", "vertical", and the like do not mean that the components must be absolutely horizontal or vertical, but can be slightly inclined. For example, "horizontal" only means that it is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly inclined.
[0031] In the description of the utility model, it needs to be explained that, unless otherwise specified and limited, the terms "set", "install", "connect", "connect" should be understood broadly, for example, it can be fixed connection, or detachable connection, or integrally connected, it can be mechanical connection, or electrical connection, it can be directly connected, or indirectly connected through intermediate medium, it can be the communication between two elements. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to specific circumstances.
[0032] As shown in Figure 1 The utility model provides a kind of comparison color card of judging the freshness degree of mammal blood sample, the comparison color card overall is circular structure, mainly including guard plate assembly 1 and comparison color card component 2.
[0033] Among them, guard plate assembly 1 includes comparison color card front guard plate 101 and comparison color card rear guard plate 102, comparison color card front guard plate 101 and comparison color card rear guard plate 102 are circular structure, after assembly, comparison color card front guard plate 101 and comparison color card rear guard plate 102 become the shell of comparison color card component 2, protect and support comparison color card component 2 between comparison color card front guard plate 101 and comparison color card rear guard plate 102.
[0034] As shown in Figure 2 Comparison color card component 2 includes multiple comparison color samples, each comparison color sample is in the form of a sector, and all comparison color samples form a complete circle after assembly. Each comparison color sample is of a different color, representing the color of blood stored for a different period of time.
[0035] In some optional embodiments, the comparison color card 3 in the comparison color card component includes six comparison color samples, namely No. 1 comparison color sample 301, No. 2 comparison color sample 302, No. 3 comparison color sample 303, No. 4 comparison color sample 304, No. 5 comparison color sample 305, and No. 6 comparison color sample 306. The six comparison color samples are six red regions of different shades, and the shades of the colors are arranged clockwise according to the length of the storage time.
[0036] For the above six comparison color samples, they can be set as the colors of blood stored for six different periods of time. For example, 0, 3, 7, 14, 21, and 28 days at room temperature, or 0, 1, 2, 3, 5, and 10 days, or 0, 5, 10, 15, 20, and 25 days, or even 0, 1, 3, 6, 12, and 24 hours, and the specific time period can be selected according to experimental requirements.
[0037] It should be noted that in the present application, the number of comparison color samples is not limited to 6, but can also be 7, 8 or 9, or more or less, and the present application does not limit this, and those skilled in the art can make comparison color samples of different time periods according to actual detection needs.
[0038] In the present application, each comparison color sample is placed on the upper surface of the color card rear backplate 102, and the central angles of each comparison color sample coincide at the center of the color card rear backplate 102. The color card assembly 2 further comprises a rivet 201 which penetrates the central angles of each comparison color sample and the center of the color card rear backplate 102 in sequence from the center of the color card front backplate 101, and the color card 3 is fixed between the color card front backplate 101 and the color card rear backplate 102 by the rivet 201, and each comparison color sample can change position around the rivet.
[0039] As shown in Figure 2 Each comparison color sample is provided with a color card slot 203, which is used to accommodate the blood sample to be tested, specifically, to accommodate a container containing the blood sample to be tested, such as a test tube, a centrifuge tube, etc.
[0040] In the present application, the shape of the color card slot 203 is designed according to the container containing the blood sample, for example: when the container is a test tube, the end of the color card slot 203 close to the center is designed as a hemisphere, and the rest is designed as a cylinder; when the container is a centrifuge tube, the end of the color card slot 203 close to the center is designed as a cone, and the rest is designed as a cylinder. The specific shape is not limited in the present application, and those skilled in the art can adjust the shape of the color card slot 203 according to the container used for actual detection.
[0041] In addition, the comparison color samples in the present application include two forms, one is a color card dyed and made according to the color of blood stored for different time periods, and the other is a color sample directly made of blood stored for different time periods.
[0042] In order to further illustrate the comparison color samples of the present application, the preparation method of the color card dyed and made according to the color of blood stored for different time periods is described here, taking sheep whole blood as an example, and the specific manufacturing steps are as follows:
[0043] S1, take sheep whole blood with red blood cell count in the normal range, take whole blood as material, take transparent blood collection tube with consistent material specifications as container, and make 6 standard color tubes of different color steps by storing samples at room temperature for 0, 3, 7, 14, 21 and 28 days, respectively, and mark them as No. 1, No. 2, No. 3, No. 4, No. 5 and No. 6;
[0044] S2. Then, adjust and mix the standard colorimeter tube color obtained in S1, and then make color cards corresponding to 6 color levels. The color card with the pick corresponds to No. 1, and the colors clockwise correspond to Nos. 2-6 respectively.
[0045] S3. Assemble the 6 color cards between the front guard plate 101 and the rear guard plate 102 of the color card to obtain the color card comparison chart.
[0046] During the above preparation process, the material specifications of each blood collection tube are consistent to ensure the accuracy of the standard color chart.
[0047] The specific procedure for creating color samples directly from blood stored for different times is as follows: blood samples stored for different times are collected and sealed into various color samples (which have the same shape as the color cards mentioned above, but whose inner cavity can be sealed with blood), thus creating color samples containing real blood. When preparing color samples in this way, the material used for the color samples is the same as the material of the container holding the blood sample to be tested. The same material facilitates comparison of the blood samples under the same conditions, thereby improving the accuracy of the comparison.
[0048] like Figure 2 and Figure 3 As shown, the curved edge of the No. 1 contrast color sample 301 is also provided with a lever 202, which is used to rotate the position of the contrast color sample on the front guard plate of the color chart.
[0049] In this invention, the front cover 101 of the colorimetric card is provided with an observation port for observing and comparing the blood sample to be tested with the contrast color sample.
[0050] Specifically, the aforementioned observation port is a fan-shaped opening on the front protective plate 101 of the colorimetric card. When the blood sample to be tested is in the colorimetric card slot 203 on the contrast color sample of this fan-shaped opening, the operator can directly observe the color contrast between the blood sample to be tested and the contrast color sample from this point, thereby judging the freshness.
[0051] The position of the pick can be set on the curved edge of the No. 1 contrast color sample 301, the curved edge of the No. 2 contrast color sample 302, or the curved edge of the No. 3 contrast color sample 303, or the curved edge of other contrast color samples, as long as the observation position of the contrast color sample can be adjusted by the pick.
[0052] In some embodiments, the blood sample to be tested is a blood sample from a mammal, such as a human, horse, cow, sheep, pig, dog, cat, rabbit, etc. It can also be a blood sample from other mammals or other non-mammals. Those skilled in the art can prepare contrast color samples of blood colors from different species according to actual testing needs.
[0053] Based on the above, the use method and principle of the comparative color card for judging the freshness degree of mammal blood sample provided in the utility model are as follows:
[0054] S1, the comparative color sample obtained by the preparation method is assembled between the front and rear protective plates 101 and 102 of the comparative color card, and is fixed by rivets 201;
[0055] S2, the container containing the blood sample to be measured is inserted into the color card slot 203 of the comparative color sample at the observation port, and then the color difference between the comparative color sample and the blood sample to be measured is observed and compared;
[0056] S3, if the color of the comparative color sample is consistent with that of the blood sample to be measured, the storage time of the blood sample to be measured is the corresponding blood storage time of the comparative color sample, and thus the judgment conclusion is obtained;
[0057] S4, if the color of the comparative color sample is inconsistent with that of the blood sample to be measured, the container containing the blood sample to be measured is taken out, the comparative color sample is moved by the dial piece 202, until the next comparative color sample moves to the observation port position, and then the container containing the blood sample to be measured is inserted into the color card slot 203 of the corresponding comparative color sample, and the color difference between the comparative color sample and the blood sample to be measured is observed and compared;
[0058] S5, if the color is consistent, the judgment conclusion can be obtained, and if the color is inconsistent, S4 is repeated until the judgment conclusion is obtained.
[0059] The utility model discloses a comparative color sample of blood color of different storage time is set, which is compared with the blood sample to be measured, and the sample to be measured and the comparative color sample can be directly compared, so that the freshness degree of the blood sample can be quickly and accurately judged. The comparative color sample of the utility model can realize high-throughput screening of blood samples of the required freshness degree, and provides convenience for high-throughput DNA extraction sample selection work.
[0060] The basic principle and main features of the utility model and the advantages of the utility model are shown and described. It should be understood by those skilled in the art that the utility model is not limited by the above examples, and the above examples and descriptions in the specification are only to illustrate the principle of the utility model, and various changes and improvements can be made without departing from the spirit and scope of the utility model. These changes and improvements all fall within the scope of the claimed utility model.
Claims
1. A comparative color chart for determining the freshness of a blood sample from a mammal, characterized in that, The comparison color card comprises a shield assembly and a color card assembly; The shield assembly is in a circular structure, comprising a color card front shield and a color card rear shield; the color card assembly is arranged between the color card front shield and the color card rear shield; The color card assembly comprises a plurality of comparison color samples, each comparison color sample is in a fan-shaped structure, arranged above the color card rear shield and uniformly distributed with the center line of the color card rear shield as the center, and the color of each comparison color sample is different; The comparison color sample is further provided with a color card slot for accommodating a comparison object; The color card front shield is provided with an observation port for observing and comparing the comparison object and the comparison color sample.
2. The contrast color card of claim 1, wherein, The color card assembly comprises at least six comparison color samples, and the color of each comparison color sample is the color of a blood sample of a different time period.
3. The contrast color card of claim 2, wherein, The material of each comparison color sample in the color card assembly is the same.
4. The contrast color card of claim 3, wherein, The comparison color sample is movably connected to the color card rear shield.
5. The contrast color card of claim 4, wherein, The center positions of the color card front shield and the color card rear shield are pierced by a rivet from top to bottom, the comparison color sample is fixed between the color card front shield and the color card rear shield through the rivet, and the comparison color sample is rotated around the rivet during use.
6. The contrast color card of claim 5, wherein, The color card assembly further comprises a dial piece arranged at the arc-shaped edge of the comparison color sample, for rotating the comparison color sample to the position of the observation port on the color card front shield.
7. The contrast color card of claim 1, wherein, The observation port is in an open structure for directly observing the comparison color sample and the comparison object at the position.