X-ray adjusting device for animal experiment and X-ray radiotherapy equipment

Abstract

The utility model provides an X-ray adjusting device and X-ray radiotherapy equipment for animal experiments, and the device comprises a fixed plate which is used for being fixed with an X-ray accelerator; the dose adjusting assembly is arranged on one side of the fixing plate, the dose adjusting assembly is telescopic, and the dose and the dose rate are changed through stretching of the dose adjusting assembly. The dose and the dose rate of the X-rays can be changed by adjusting the length of the dose adjusting assembly.

Description

Technical Field

[0001] This utility model relates to the field of radiotherapy technology, specifically to an X-ray modulation device and X-ray radiotherapy equipment for animal experiments. Background Technology

[0002] In mouse radiotherapy experiments, the selection of radiation field, dose, and dose rate are crucial aspects of experimental design, directly impacting treatment efficacy and the reliability of experimental data. The selection of radiation field, dose, and dose rate is typically based on tumor type, experimental objectives, and treatment regimen.

[0003] However, current mouse radiotherapy experimental devices still have certain limitations in terms of X-ray dose and dose rate adjustment. In order to meet the needs of different animal experiments, there is an urgent need for an X-ray adjustment device and X-ray radiotherapy equipment for animal experiments that can flexibly adjust the dose and dose rate. Utility Model Content

[0004] The purpose of this invention is to overcome the above-mentioned technical deficiencies and provide an X-ray adjustment device and X-ray radiotherapy equipment for animal experiments, so as to solve the technical problem that there are still certain limitations in the adjustment of X-ray dose and dose rate in related technologies.

[0005] To achieve the above-mentioned technical objectives, the present invention adopts the following technical solution: It provides an X-ray adjustment device for animal experiments, the X-ray adjustment device being fixed to an X-ray accelerator, comprising:

[0006] A fixing plate for fixing to the X-ray accelerator;

[0007] A primary collimator, which is connected to the X-ray accelerator;

[0008] A leveler, wherein the leveler is detachably connected to the primary collimator;

[0009] A dose adjustment component is disposed on one side of the fixed plate. The dose adjustment component is retractable, and the dose and dose rate are changed by extending and retracting the dose adjustment component.

[0010] Furthermore, the dose adjustment component includes:

[0011] A sleeve is disposed on one side of the fixed plate and is fixed to the primary collimator;

[0012] A telescopic cylinder, which is slidably disposed relative to the sleeve.

[0013] Furthermore, the dose adjustment component includes:

[0014] A positioning hole is provided on the telescopic cylinder;

[0015] A limiting rod is threadedly connected to the sleeve and to the positioning hole.

[0016] Furthermore, the X-ray adjustment device also includes a replacement component, which includes:

[0017] A support platform is detachably disposed from the equalizer, and the support platform is slidably disposed relative to the primary collimator;

[0018] A connecting plate, which is fixed to the support platform and slidably disposed relative to the primary collimator;

[0019] A handle is provided at the end of the connecting plate away from the support platform.

[0020] Furthermore, the X-ray adjustment device also includes a fine-tuning component, which includes:

[0021] A sliding plate is slidably disposed relative to a fixed plate, and the sliding plate and the fixed plate are connected by an adjustment part;

[0022] The first through slot is formed on the sliding plate, and the center of the first through slot coincides with the midpoint of the sliding plate. The first through slot is correspondingly set with the primary collimator.

[0023] A groove is formed on the sliding plate, and the fixing plate is disposed within the groove;

[0024] A side plate is fixed to the sliding plate. The side plate is symmetrically arranged about the central axis of the sliding plate. The side plate and the fixed plate are adjusted in position by an adjustment part.

[0025] Furthermore, a second through groove is provided on the fixing plate, and the side plate is slidably disposed within the second through groove; and / or,

[0026] The fixing plate has a third through slot, and the primary collimator is installed in the third through slot.

[0027] Furthermore, the adjusting part includes a first bolt, which is threadedly connected to the sliding plate, passes through the sliding plate into a groove, and abuts against the fixed plate; and / or,

[0028] The adjusting part includes a second bolt, which is threadedly connected to the side plate and abuts against the fixing plate.

[0029] Furthermore, the X-ray modulation device also includes a radiation shielding assembly, which comprises:

[0030] A first plexiglass block is slidably disposed relative to the telescopic cylinder, and the telescopic cylinder is provided with a first opening for removing the first plexiglass block.

[0031] The radiation field lead block has a first plexiglass block on one side, the radiation field lead block abuts against the first plexiglass block, and the radiation field lead block has a second opening for X-rays to pass through.

[0032] A tungsten block is embedded on the outside of the lead block in the firing field, and the tungsten block abuts against the lead block in the firing field;

[0033] An outer lead block is disposed on the outside of the tungsten block and abuts against the tungsten block;

[0034] The first steel plate is fixed to the telescopic cylinder and abuts against the outer lead block;

[0035] The second steel plate abuts against the outer lead block, and the second steel plate and the first steel plate clamp the outer lead block. The second steel plate and the first steel plate are fixed by screws.

[0036] A square steel plate is used to support the lead block and the tungsten block in the firing field, the outer lead block, and the second steel plate.

[0037] Furthermore, multiple lead blocks are provided for the firing field, and each lead block has a different opening size.

[0038] Furthermore, the X-ray conditioning device also includes an ionization chamber, which is disposed on the side of the support platform away from the homogenizer. A bracket is disposed on one side of the ionization chamber, which is disposed on the side away from the connecting plate. The bracket and the side plate are slidably disposed relative to each other.

[0039] An X-ray radiotherapy device includes an X-ray accelerator and an X-ray modulation device for animal experiments disposed on the X-ray accelerator.

[0040] Beneficial effects:

[0041] 1. By adjusting the length of the dose adjustment component, the dose and dose rate of X-rays can be changed to meet different experimental needs and solve the technical problem that there are still certain limitations in the adjustment of X-ray dose and dose rate in related technologies.

[0042] 2. By pulling the handle, the connecting plate and support platform can be moved, thereby detaching the support platform from the primary collimator. This allows the homogenizer on the support platform to be disassembled, enabling FFF mode irradiation. It also supports the replacement of different first acrylic blocks to meet different experimental needs and enhance the flexibility of the system.

[0043] 3. By adjusting the first bolt, the entire device can be moved ±5mm along the x-direction, and by adjusting the second bolt, the entire device can be moved ±5mm along the y-direction, ensuring that the central axis of the device is precisely aligned with the central axis of the beam, thereby achieving fine-tuning to align with the beam center.

[0044] 4. By changing the lead blocks in the radiation field, different radiation fields can be achieved to meet different experimental needs. Attached Figure Description

[0045] Figure 1 This is a schematic diagram of the overall structure of an X-ray adjustment device and X-ray radiotherapy equipment used in animal experiments according to an embodiment of this utility model;

[0046] Figure 2 This is a schematic diagram of the separation structure of the fine-tuning component and the primary collimator of an X-ray adjustment device and X-ray radiotherapy equipment used in animal experiments, as described in an embodiment of this utility model.

[0047] Figure 3 This is a schematic diagram of the structure of a fine-tuning component of an X-ray adjustment device and an X-ray radiotherapy equipment used in animal experiments, as described in an embodiment of this utility model.

[0048] Figure 4 This is a schematic diagram of the structure of a replacement component of an X-ray adjustment device and an X-ray radiotherapy equipment used in animal experiments, as described in an embodiment of this utility model.

[0049] Figure 5 This is a schematic diagram of a dose adjustment component of an X-ray adjustment device and X-ray radiotherapy equipment for animal experiments, provided by an embodiment of this utility model.

[0050] Figure 6 This is a schematic diagram of the structure of an X-ray adjustment device for animal experiments and a radiation field shielding component of an X-ray radiotherapy equipment used in an embodiment of this utility model;

[0051] Figure 7 This is a schematic diagram of the telescopic cylinder of an X-ray adjustment device and an X-ray radiotherapy equipment used in animal experiments, as described in an embodiment of this utility model.

[0052] Figure 8 This invention relates to an X-ray modulation device and X-ray radiotherapy equipment used in animal experiments. Figure 7Schematic diagram of the telescopic cylinder AA in the middle;

[0053] Figure 9 This is a schematic diagram of the second steel plate and square steel plate structure of an X-ray adjustment device and X-ray radiotherapy equipment used in animal experiments, as described in an embodiment of this utility model.

[0054] The above figures include the following reference numerals:

[0055] 1. Fixing plate;

[0056] 2. Primary collimator;

[0057] 3. Leveler;

[0058] 4. Dosage adjustment assembly; 41. Sleeve; 42. Telescopic cylinder; 43. Positioning hole; 44. Limiting rod;

[0059] 5. Replace components; 51. Support platform; 52. Connecting plate; 53. Handle;

[0060] 6. Fine-tuning component; 61. Sliding plate; 62. First through slot; 63. Groove; 64. Side plate;

[0061] 7. Adjustment part; 71. First bolt; 72. Second bolt;

[0062] 8. Radiation shielding assembly; 81. First plexiglass block; 82. Radiation field lead block; 83. Tungsten block; 84. Outer lead block; 85. First steel plate; 86. Second steel plate; 87. Square steel plate;

[0063] 9. Ionization chamber;

[0064] 10. Bracket;

[0065] 11. Second through slot;

[0066] 12. Third through slot;

[0067] 13. First opening. Detailed Implementation

[0068] To enable those skilled in the art to better understand the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present application, and not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort should fall within the scope of protection of the present application.

[0069] According to an embodiment of this utility model, an X-ray modulation device and an X-ray radiotherapy device for animal experiments are provided. Please refer to [link to relevant documentation]. Figures 1 to 9 The X-ray adjustment device, used for fixing to an X-ray accelerator, includes: a fixing plate 1 for fixing to the X-ray accelerator; a primary collimator 2 connected to the X-ray accelerator; a homogenizer 3 detachably connected to the primary collimator 2; and a dose adjustment assembly 4 disposed on one side of the fixing plate 1, connected to the primary collimator 2, and extendable to change the dose and dose rate.

[0070] By adopting the above technical solution and adjusting the length of the dose adjustment component 4, the dose and dose rate of X-rays can be changed to meet different experimental needs and solve the technical problem that there are still certain limitations in the adjustment of X-ray dose and dose rate in related technologies.

[0071] Please refer to Figure 1 and Figure 5 The dose adjustment assembly 4 includes: a sleeve 41, which is fixed to the primary collimator 2; and a telescopic cylinder 42, which is slidably disposed relative to the sleeve 41.

[0072] By adopting the above technical solution, the overall length is changed by sliding the sleeve 41 and the telescopic cylinder 42.

[0073] Please refer to Figure 1 and Figure 5 The dosage adjustment component 4 includes: a positioning hole 43, which is formed on the telescopic cylinder 42 and is symmetrically distributed around the central axis of the telescopic cylinder 42; and a limiting rod 44, which is threadedly connected to the sleeve 41 and threadedly connected to the positioning hole 43.

[0074] By adopting the above technical solution, the sleeve 41 and the telescopic cylinder 42 can be fixed by connecting the limiting rod 44 and the positioning hole 43.

[0075] Please refer to Figure 1 and Figure 4 The X-ray adjustment device further includes a replacement component 5, which includes: a support platform 51, which is detachably disposed from the homogenizer 3 and slidably disposed relative to the primary collimator 2; a connecting plate 52, which is fixed to the support platform 51 and slidably disposed relative to the primary collimator 2; and a handle 53, which is disposed at the end of the connecting plate 52 away from the support platform 51.

[0076] By adopting the above technical solution, by pulling the handle 53, the handle moves the connecting plate 52 and the support platform 51, thereby causing the support platform 51 to detach from the primary collimator 2. This makes the homogenizer 3 on the support platform 51 detachable, enabling FFF mode irradiation, meeting different experimental needs, and enhancing the flexibility of the system.

[0077] Please refer to Figure 1 and Figure 3 The X-ray adjustment device further includes a fine-tuning component 6, which includes: a sliding plate 61, which is slidably disposed relative to the fixed plate 1 and connected to the fixed plate 1 via an adjustment part 7; a first through groove 62, which is formed on the sliding plate 61, with the center of the first through groove 62 coinciding with the midpoint of the sliding plate 61, and corresponding to the primary collimator 2; a groove 63, which is formed on the sliding plate 61 and in which the fixed plate 1 is disposed; and a side plate 64, which is fixed to the sliding plate 61 and is symmetrically arranged about the central axis of the sliding plate 61, with the side plate 64 and the fixed plate 1 adjusted in position via the adjustment part 7.

[0078] By adopting the above technical solution, the entire device is fixed to the head of the accelerator by the fixing plate 1, ensuring that the central axis of the device is precisely aligned with the central axis of the beam, thus guaranteeing system stability and radiation accuracy. The adjustment unit 7 allows the entire device to achieve a range of motion of ±5mm in both the x and y directions, enabling fine-tuning to align with the beam center.

[0079] Please refer to Figure 1 and Figure 3 The fixing plate 1 has a second through groove 11, and the side plate 64 is slidably disposed in the second through groove 11; and / or, the fixing plate 1 has a third through groove 12, and the primary collimator 2 is disposed in the third through groove 12.

[0080] By adopting the above technical solution, the side plate slides within the second through groove 11, which facilitates increased stability for later adjustments.

[0081] Please refer to Figure 1 and Figure 3 The adjusting part 7 includes a first bolt 71, which is threadedly connected to the sliding plate 61. The first bolt 71 passes through the sliding plate 61 into the groove 63 and abuts against the fixing plate 1; and / or, the adjusting part 7 includes a second bolt 72, which is threadedly connected to the side plate 64 and abuts against the fixing plate 1.

[0082] By adopting the above technical solution, adjusting the first bolt 71 can move the entire device ±5mm along the x-direction, and adjusting the second bolt 72 can move the entire device ±5mm along the y-direction, ensuring that the central axis of the device is precisely aligned with the central axis of the beam. Since the entire device is set on the middle sliding plate 61, the movement of the sliding plate 61 ±5mm along the x and y directions is equivalent to the entire device being able to move ±5mm along the x and y directions.

[0083] Please refer to Figure 1 , Figure 6 and Figure 8 The X-ray adjustment device further includes a radiation shielding assembly 8, which comprises: a first plexiglass block 81, which is slidably disposed relative to the telescopic cylinder 42, the telescopic cylinder 42 having a first opening 13 for removing the first plexiglass block 81; a radiation field lead block 82, on one side of which the first plexiglass block 81 is disposed, the radiation field lead block 82 abutting against the first plexiglass block 81, the radiation field lead block 82 having a second opening for X-rays to pass through; a tungsten block 83, which is embedded on the outside of the radiation field lead block 82, the tungsten block 83 abutting against the radiation field lead block 82; and an outer lead block 84. The outer lead block 84 is disposed on the outside of the tungsten block 83 and abuts against the tungsten block 83; the first steel plate 85 is fixed to the telescopic cylinder 42 and abuts against the outer lead block 84; the second steel plate 86 abuts against the outer lead block 84 and clamps the outer lead block 84 with the first steel plate 85, and the second steel plate 86 is fixed to the first steel plate 85 with screws; the square steel plate 87 abuts against the firing field lead block 82, the tungsten block 83, the outer lead block 84 and the second steel plate 86, and the square steel plate 87 is used to support the firing field lead block 82 and the tungsten block 83.

[0084] By adopting the above technical solution, a first plexiglass block 81, a field lead block 82, and an outer lead block 84 are set at the lower end of the telescopic cylinder 42. The field lead block 82 and the outer lead block 84 are separated by an embedded tungsten block 83 to prevent the deformation of the lead from causing the lead blocks to not fit well, thereby reducing the difficulty of equipment connection. A large lead block is used on the periphery to control the penumbra of the field.

[0085] To further enhance radiation protection, the tungsten block 83 adopts a stepped design to prevent radiation leakage between the tungsten block and the lead block. A square steel plate 87 is installed at the bottom of the system to stably support the lead block 82 and the tungsten block 83 in the radiation field, ensuring the stability and safety of the entire system.

[0086] Please refer to Figure 8 Multiple shooting field lead blocks 82 are provided, and the second opening size of each shooting field lead block 82 is different.

[0087] By adopting the above technical solution, in order to meet the experimental requirements of different irradiation sites, lead blocks 82 with different second opening sizes are designed to realize the replacement of different irradiation fields and meet different radiation damage models.

[0088] Please refer to Figure 1 The X-ray adjustment device further includes an ionization chamber 9, which is located on the side of the support platform 51 away from the homogenizer 3. A bracket 10 is provided on one side of the ionization chamber 9, which is located on the side away from the connecting plate 52. The bracket 10 is slidably arranged relative to the side plate 64.

[0089] By adopting the above technical solution and setting up the ionization chamber 9, it is possible to accurately measure and monitor the dose and dose rate of X-rays, ensuring the accuracy and consistency of radiation levels during the experiment.

[0090] An X-ray radiotherapy device includes an X-ray accelerator and an X-ray modulation device for animal experiments disposed on the X-ray accelerator.

[0091] The primary collimator 2 has a frustum-shaped structure made of 304 stainless steel, with an upper radius of 27.2 mm and a lower radius of 47.54 mm, and a height of 89 mm. The primary collimator 2 is connected to the equalizer 3 and the ionization chamber 9 below, and side plates 64 are provided on both sides to support the ionization chamber 9 and the equalizer 3. The equalizer 3 is detachable, and a second plexiglass block with a thickness of 2 cm can be replaced to adapt to different experimental needs. A new equalizer 3 can be installed on the second plexiglass block to ensure that the flatness and symmetry under different radiation fields meet experimental requirements. Simultaneously, the second plexiglass block can also effectively eliminate leaky electrons.

[0092] The dosage adjustment component 4, located at the bottom, is rectangular in shape with an opening size of 60mm x 60mm and is made of 304 stainless steel. The dosage adjustment component 4 features a telescopic structure, allowing its length to be adjusted between 400mm and 565mm in 15mm increments. The sleeve 41 and the telescopic sleeve 42 are secured with screws. This design effectively improves the system's flexibility and adaptability.

[0093] This device is specifically designed for X-ray accelerators to provide a precise and stable radiation environment. With the accelerator gantry angle fixed at 0°, the device ensures that the beam's central axis passes perpendicularly through the collimator, homogenizer, and ionization chamber, thereby achieving precise control of the radiation field. Through the homogenizer, the device can adjust key parameters such as beam symmetry, homogenization, and penumbra, ensuring the radiation field complies with relevant national regulations and safety standards, guaranteeing the reliability and accuracy of experimental data. Furthermore, the device supports a homogenizer-free (FFF) mode, suitable for special experimental scenarios requiring more direct radiation output. During experiments, the effective application of the first and second acrylic glass blocks eliminates the influence of missed electrons on the radiation field, further ensuring the radiation field is identical to clinical conditions and the accuracy of the data. The device is designed to provide a high-precision, high-safety, and high-stability radiation environment for animal experiments, meeting various experimental needs and ensuring radiation safety complies with relevant regulations.

[0094] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented in sequences other than those illustrated or described herein.

[0095] Optionally, specific examples in this embodiment can refer to the examples described in the above embodiments, and will not be repeated here.

[0096] The sequence numbers of the embodiments in this application are for descriptive purposes only and do not represent the superiority or inferiority of the embodiments.

[0097] In the above embodiments of this application, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions of other embodiments.

[0098] The above description is only a preferred embodiment of this application. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of this application, and these improvements and modifications should also be considered within the scope of protection of this application.

Claims

1. An X-ray modulation device for animal experiments, the X-ray modulation device being fixed to an X-ray accelerator, characterized in that, include: Fixing plate (1), the fixing plate (1) is used to fix the X-ray accelerator; A dose adjustment component (4) is disposed on one side of the fixed plate (1). The dose adjustment component (4) is retractable, and the dose and dose rate are changed by the retraction and extension of the dose adjustment component (4).

2. The X-ray modulation device for animal experiments according to claim 1, characterized in that, The dose adjustment component (4) includes: Sleeve (41), the sleeve (41) is disposed on one side of the fixing plate (1); Telescopic cylinder (42), which is slidably disposed relative to the sleeve (41); Positioning hole (43), the positioning hole (43) is formed on the telescopic cylinder (42); The limiting rod (44) is threadedly connected to the sleeve (41) and the positioning hole (43).

3. The X-ray modulation device for animal experiments according to claim 2, characterized in that, The X-ray modulation device further includes: Primary collimator (2), the primary collimator (2) is connected to the X-ray accelerator, and the primary collimator (2) is fixedly connected to the sleeve (41); A leveler (3) is detachably connected to the primary collimator (2).

4. The X-ray modulation device for animal experiments according to claim 3, characterized in that, The X-ray modulation device further includes a replacement component (5), which includes: The support platform (51) is detachably disposed from the leveler (3) and is slidably disposed relative to the primary collimator (2); A connecting plate (52) is fixed to the support platform (51), and the connecting plate (52) is slidably disposed relative to the primary collimator (2); A handle (53) is provided at one end of the connecting plate (52) away from the support platform (51).

5. The X-ray modulation device for animal experiments according to claim 4, characterized in that, The X-ray adjustment device further includes a fine-tuning component (6), which includes: A sliding plate (61) is slidably disposed relative to the fixed plate (1), and the sliding plate (61) and the fixed plate (1) are connected by an adjustment part (7); The first through groove (62) is formed on the sliding plate (61), and the center of the first through groove (62) coincides with the midpoint of the sliding plate (61). The first through groove (62) is correspondingly set with the primary collimator (2). A groove (63) is formed on the sliding plate (61), and the fixing plate (1) is provided in the groove (63). Side plate (64), the side plate (64) is fixed to the sliding plate (61), the side plate (64) is symmetrically arranged about the central axis of the sliding plate (61), and the side plate (64) and the fixed plate (1) are adjusted in position by the adjustment part (7).

6. The X-ray modulation device for animal experiments according to claim 5, characterized in that, The fixing plate (1) has a second through groove (11), and the side plate (64) is slidably disposed within the second through groove (11); and / or, The fixing plate (1) has a third through groove (12), and the primary collimator (2) is installed in the third through groove (12).

7. The X-ray modulation device for animal experiments according to claim 5, characterized in that, The adjusting part (7) includes a first bolt (71) threadedly connected to the sliding plate (61), the first bolt (71) passing through the sliding plate (61) into the groove (63), and the first bolt (71) abutting against the fixing plate (1); and / or, The adjusting part (7) includes a second bolt (72), which is threadedly connected to the side plate (64) and abuts against the fixing plate (1).

8. The X-ray modulation device for animal experiments according to claim 2, characterized in that, The X-ray modulation device further includes a radiation shielding assembly (8), which comprises: The first plexiglass block (81) is slidably disposed relative to the telescopic cylinder (42), and the telescopic cylinder (42) is provided with a first opening (13) for removing the first plexiglass block (81). A radiation field lead block (82) is provided with a first plexiglass block (81) on one side of the radiation field lead block (82), the radiation field lead block (82) abuts against the first plexiglass block (81), and the radiation field lead block (82) is provided with a second opening for X-rays to pass through; A tungsten block (83) is embedded on the outside of the lead block (82) in the shooting field, and the tungsten block (83) abuts against the lead block (82) in the shooting field; An outer lead block (84) is disposed on the outside of the tungsten block (83) and abuts against the tungsten block (83); The first steel plate (85) is fixed to the telescopic cylinder (42), and the first steel plate (85) abuts against the outer lead block (84); The second steel plate (86) abuts against the outer lead block (84), and the second steel plate (86) and the first steel plate (85) clamp the outer lead block (84). The second steel plate (86) and the first steel plate (85) are fixed by screws. A square steel plate (87) abuts against the field lead block (82), the tungsten block (83), the outer lead block (84), and the second steel plate (86). The square steel plate (87) is used to support the field lead block (82) and the tungsten block (83).

9. The X-ray modulation device for animal experiments according to claim 5, characterized in that, The X-ray conditioning device further includes an ionization chamber (9), which is located on the side of the support platform (51) away from the homogenizer (3). A bracket (10) is provided on one side of the ionization chamber (9), which is located on the side away from the connecting plate (52). The bracket (10) is slidably arranged relative to the side plate (64).

10. An X-ray radiotherapy device, characterized in that, Includes an X-ray accelerator and an X-ray modulation device for animal experiments as described in any one of claims 1 to 9, disposed on the X-ray accelerator.

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