Vacuum defoaming processor for preparing medical grade collagen

Abstract

The utility model relates to the technical field of collagen processing, in particular to a vacuum defoaming treater for preparing medical grade collagen, which comprises a treater support, a defoaming barrel is arranged on the treater support, a pressing plate is arranged inside the defoaming barrel, and a vacuum pump is arranged on the treater support. The defoaming barrel body is made of a high-temperature-resistant, sterilizable, transparent and visible polymethyl methacrylate or polypropylene material, so that a production operator can conveniently observe the conditions of feeding, discharging and defoaming, the material loss is reduced, and the difficulty in observation of the production operator due to a small visible range is reduced, a defoaming barrel top cover is arranged on the upper side of the defoaming barrel body, and the defoaming barrel top cover is arranged on the lower side of the defoaming barrel body. A connecting pipe is arranged on a top cover of the defoaming barrel in a penetrating mode, and an air assembly is arranged on the left side of the connecting pipe and comprises an air compressor, a first air pipe, a pressure regulating valve, a second air pipe, a pressure display meter, a third air pipe, an air filter, a fourth air pipe, an air control valve and a fifth air pipe. A vacuum assembly is arranged on the right side of the connecting pipe and comprises a first vacuum pipe, a vacuum control valve, a second vacuum pipe, a vacuum filter, a third vacuum pipe and a defoaming vacuum pump, meanwhile, the air assembly and the vacuum assembly are made of sterilizable materials, the whole processor can be sterilized, and the sterile operation difficulty is reduced; and the final sterile state of the collagen is ensured.

Description

TECHNICAL FIELD

[0001] The utility model relates to collagen processing technical field more specifically, relate to a medical grade collagen preparation vacuum defoaming processor. BACKGROUND

[0002] Collagen is not only a biological macromolecule, the main component in animal connective tissue, but also the most abundant and widely distributed functional protein in mammalian body. As a medical biomaterial, collagen has important characteristics such as low immunogenicity, good biocompatibility and biodegradable safety, good absorption and adhesion, and is widely used in medical clinical, first aid and other fields. However, due to the fact that bubbles are easily produced in the production process of collagen, which affects the product quality and stability, and increases the risk in the use of medical field, therefore, in the production process of medical grade collagen, defoaming treatment becomes more and more important. In the existing defoaming treatment technology, the method of centrifugation may cause uneven material or even stratification, and heating and acoustic defoaming may cause collagen denaturation to different degrees. By reasonably controlling the vacuum degree, the purpose of defoaming can be achieved by using the vacuum defoaming method.

[0003] The existing vacuum defoaming treatment device is not suitable for defoaming of easy-foaming high-viscosity materials. On the one hand, the material is difficult to take out or remains after defoaming, causing material waste. On the other hand, the stainless steel tank used has a small visible range, which makes it impossible for the production operator to observe the vacuum condition in time and causes the material to be sucked back. Since medical grade collagen needs to be sterile, most of the existing devices are industrial grade and have stirring rods, which cannot guarantee that all parts in contact with the material, including air, are sterile, and thus cannot guarantee the final sterile state of the material. In view of the above problems, a solution is proposed as follows. UTILITY MODEL CONTENTS

[0004] The utility model aims at providing a medical grade collagen preparation vacuum defoaming processor to solve the problems in the background art.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme:

[0006] A medical grade collagen preparation vacuum defoaming processor, comprising a processor support, a defoaming barrel body is arranged on the processor support, a feed inlet and a defoaming barrel handle are arranged on the left side of the defoaming barrel body, a discharge port is arranged at the bottom of the defoaming barrel body, a defoaming barrel handle is arranged on the right side of the defoaming barrel body, a defoaming barrel top cover is arranged on the upper side of the defoaming barrel body, a connecting pipe is arranged through the defoaming barrel top cover, the upper side of the connecting pipe is connected with a pressure display connecting pipe snap ring, the lower side of the connecting pipe passes through the center shaft of the defoaming barrel top cover, an air assembly is arranged on the left side of the connecting pipe, and a vacuum assembly is arranged on the right side of the connecting pipe.

[0007] Further, the defoaming barrel adopts transparent and visible polymethyl methacrylate or polypropylene material which is resistant to high temperature and sterilizable.

[0008] Further, the feeding port is provided with a feeding port cover plate which plays a sealing and bacteria blocking role, and feeding port on-off valves are fixedly connected to the left and right sides of the feeding port cover plate.

[0009] Further, the discharging port is provided with a discharging port cover plate which plays a sealing and bacteria blocking role, and discharging port on-off valves are fixedly connected to the left and right sides of the discharging port cover plate.

[0010] Further, the defoaming barrel is provided with a pressing plate, the thickness of the pressing plate is 3-5mm, the diameter of the pressing plate is 0.5-1.5mm smaller than that of the defoaming barrel, and the pressing plate is made of medical-grade polypropylene material, polytetrafluoroethylene material or polyethylene terephthalate material which is sterilizable and non-toxic.

[0011] Further, the pressure display and the pressure display table are made of stainless steel material which is resistant to high temperature, sterilizable and corrosion-resistant, and the pressure display is provided with positive pressure and negative pressure display functions.

[0012] Further, the defoaming barrel top cover is made of stainless steel material which is sterilizable, resistant to high temperature and corrosion-resistant, the defoaming barrel top cover is fixedly connected to the defoaming barrel by a defoaming barrel top cover clamp which plays a sealing role, the defoaming barrel top cover clamp is provided with a defoaming barrel top cover clamp switch, the connecting pipe provided on the defoaming barrel top cover is integrated, and the connecting pipe and the connecting pipe clamp are made of stainless steel material which is sterilizable, resistant to high temperature and corrosion-resistant.

[0013] Further, the air assembly comprises an air compressor, a first air pipe, a pressure regulating valve, a second air pipe, a pressure display meter, a third air pipe, an air filter, a fourth air pipe, an air control valve and a fifth air pipe, the air compressor is connected with the left side of the first air pipe through a clasp ring, the right side of the first air pipe is connected with the air inlet of the pressure regulating valve through a clasp ring, the air outlet of the pressure regulating valve is connected with the left side of the second air pipe through a clasp ring, the right side of the second air pipe is connected with the left side of the pressure display meter through a clasp ring, the right side of the pressure display meter is connected with the left side of the third air pipe through a clasp ring, the right side of the third air pipe is connected with the left side of the air filter through a clasp ring, the right side of the air filter is connected with the left side of the fourth air pipe through a clasp ring, the right side of the fourth air pipe is connected with the left side of the air control valve through a clasp ring, the right side of the air control valve is connected with the left side of the fifth air pipe through a clasp ring, and the right side of the fifth air pipe is connected with the connecting pipe through a connecting pipe clasp ring; the air filter has a pore size of 0.22 microns; the first air pipe, the second air pipe, the third air pipe, the fourth air pipe and the fifth air pipe are made of a high-temperature-resistant and sterilizable polytetrafluoroethylene material.

[0014] Further, the vacuum assembly comprises a first vacuum pipe, a vacuum control valve, a second vacuum pipe, a vacuum filter, a third vacuum pipe and a defoaming vacuum pump, the left side of the first vacuum pipe is connected with the right side of the connecting pipe through a connecting pipe clasp ring, the right side of the first vacuum pipe is connected with the left side of the vacuum control valve through a clasp ring, the right side of the vacuum control valve is connected with the left side of the second vacuum pipe through a clasp ring, the right side of the second vacuum pipe is connected with the left side of the vacuum filter through a clasp ring, the right side of the vacuum filter is connected with the left side of the third vacuum pipe through a clasp ring, the right side of the third vacuum pipe is connected with the defoaming vacuum pump through a clasp ring, and the clasp ring is made of a sterilizable stainless steel material; the vacuum filter has a pore size of 0.22 microns; the first vacuum pipe, the second vacuum pipe and the third vacuum pipe are made of a high-temperature-resistant and sterilizable polytetrafluoroethylene material.

[0015] Compared with the prior art, the utility model has the advantages that:

[0016] (1) The defoaming barrel is visible, which facilitates the observation of feeding, discharging and defoaming by production operators, reduces the difficulty in observation of production operators caused by a small visible range, reduces material loss and saves production time.

[0017] (2) The defoaming barrel, the defoaming barrel top cover, the pressing plate, the pressure display meter, the connecting pipe, the connecting pipe clasp ring, the first air pipe, the second air pipe, the third air pipe, the fourth air pipe, the fifth air pipe, the first vacuum pipe, the second vacuum pipe, the third vacuum pipe, the pressure display meter and the clasp ring are made of sterilizable materials, and the whole can be sterilized at high temperature after assembly, which reduces the risk of contamination and is conducive to ensuring the final sterile state of collagen.

[0018] (3) The air filter and vacuum filter are arranged, which can filter the air in the air pipe and vacuum pipe, remove impurities and purify the air, so that the air entering the defoaming barrel reaches a sterile state.

[0019] (4) The defoaming barrel is internally provided with a pressing plate, which can prevent the material from being lifted and sucked back during vacuumizing, and can press the material in the defoaming barrel downward to facilitate the discharge of the material, reduce the difficulty in discharging the material due to high viscosity and the loss of the material due to wall sticking, and improve the yield. BRIEF DESCRIPTION OF DRAWINGS

[0020] In order to more clearly illustrate the present application, the specific embodiments of the present application will be further described in detail below with reference to the accompanying drawings.

[0021] Figure 1 It is a schematic diagram of the overall structure of the present application.

[0022] Figure 2 It is a schematic diagram of the top cover structure of the defoaming barrel.

[0023] Figure 3 It is a schematic diagram of the air assembly structure.

[0024] Figure 4 It is a schematic diagram of the vacuum assembly structure.

[0025] Explanation of reference numerals in the drawings:

[0026] 1, pressure display; 2, air assembly; 21, air compressor; 22, first air pipe; 23, pressure regulating valve; 24, second air pipe; 25, pressure display meter; 26, third air pipe; 27, air filter; 28, fourth air pipe; 29, air control valve; 210, fifth air pipe; 3, vacuum assembly; 31, first vacuum pipe; 32, vacuum control valve; 33, second vacuum pipe; 34, vacuum filter; 35, third vacuum pipe; 36, defoaming vacuum pump; 4, defoaming barrel; 5, defoaming barrel top cover; 51, defoaming barrel top cover clamp switch; 52, defoaming barrel top cover clamp; 6, connecting pipe clamp ring; 7, connecting pipe; 8, pressing plate; 9, feed inlet cover plate; 10, feed inlet; 11, feed inlet switch valve; 12, defoaming barrel handle; 13, discharge outlet; 14, discharge outlet cover plate; 15, discharge outlet switch valve; 16, processor support; 17, clamp ring. DETAILED DESCRIPTION

[0027] Clearly, the described embodiments are merely a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0028] Please refer to Figures 1-4 The utility model provides a kind of technical scheme: a medical grade collagen preparation is handled with vacuum defoaming processor: defoaming bucket body 4 is provided on processor support 16, defoaming bucket body 4 uses transparent and visible polymethyl methacrylate or polypropylene material of high temperature resistance, sterilizable, it is convenient for production operator to observe feed, discharge, defoaming etc.; defoaming bucket body 4 inside is provided with pressing plate 8, reduces the loss of material due to material backwash, difficult discharge and discharge wall hanging, improves yield, pressing plate 8 uses the medical grade polypropylene material or polytetrafluoroethylene material or polyethylene terephthalate material that can be high-temperature sterilized and non-toxic;Defoaming bucket body 4 left side is provided with U-shaped feed inlet 10 and defoaming bucket handle 12, feed inlet 10 upper end is provided with feed inlet cover plate 9 playing the role of sealing bacteria blocking, feed inlet cover plate 9 left and right sides are provided with feed inlet switch valve 11 fixed connection;Defoaming bucket body 4 bottom is provided with discharge port 13, discharge port 13 bottom passes through processor support 16 bottom end center shaft, discharge port 13 is provided with discharge port cover plate 14 playing the role of sealing bacteria blocking, discharge port cover plate 14 left and right sides are provided with discharge port switch valve 15 fixed connection;Defoaming bucket body 4 right side is provided with defoaming bucket handle 12, defoaming bucket body 4 upper side is provided with defoaming bucket top cover 5, defoaming bucket top cover 5 uses stainless steel material that can be sterilized, high temperature resistant and corrosion resistant, defoaming bucket top cover 5 and defoaming bucket body 4 are fixedly connected with defoaming bucket top cover clamp 52 playing the role of sealing, and the defoaming bucket top cover clamp 52 is provided with defoaming bucket top cover clamp switch 51, and the defoaming bucket top cover 5 is provided with connecting pipe 7, and the connecting pipe 7 is integrally arranged, and the upper side of the connecting pipe 7 is connected with the pressure display 1 by connecting pipe clasp 6, and the lower side of the connecting pipe 7 passes through the center shaft of the defoaming bucket top cover 5, and the left side of the connecting pipe 7 is provided with air assembly 2, and the right side of the connecting pipe 7 is provided with vacuum assembly 3, and the connecting pipe 7 and the connecting pipe clasp 6 are made of stainless steel material that can be sterilized, high temperature resistant and corrosion resistant, and can be sterilized as a whole, to avoid the difficulty of sterilization causing damage to the performance of collagen, and protect the performance stability of collagen.

[0029] The air assembly 2 comprises an air compressor 21, a first air pipe 22, a pressure regulating valve 23, a second air pipe 24, a pressure display meter 25, a third air pipe 26, an air filter 27, a fourth air pipe 28, an air control valve 29 and a fifth air pipe 210, the right side of the air compressor 21 is connected with the left side of the first air pipe 22 by a clasp 17, the right side of the first air pipe 22 is connected with the air inlet of the pressure regulating valve 23 by the clasp 17, the air outlet of the pressure regulating valve 23 is connected with the left side of the second air pipe 24 by the clasp 17, the right side of the second air pipe 24 is connected with the left side of the pressure display meter 25 by the clasp 17, the right side of the pressure display meter 25 is connected with the left side of the third air pipe 26 by the clasp 17, the right side of the third air pipe 26 is connected with the left side of the air filter 27 by the clasp 17, the right side of the air filter 27 is connected with the left side of the fourth air pipe 28 by the clasp 17, the right side of the fourth air pipe 28 is connected with the left side of the air control valve 29 by the clasp 17, the right side of the air control valve 29 is connected with the left side of the fifth air pipe 210 by the clasp 17, and the right side of the fifth air pipe 210 is connected with the connecting pipe 7 by a connecting pipe clasp 6. The vacuum assembly 3 comprises a first vacuum pipe 31, a vacuum control valve 32, a second vacuum pipe 33, a vacuum filter 34, a third vacuum pipe 35 and a defoaming vacuum pump 36, the left side of the first vacuum pipe 31 is connected with the right side of the connecting pipe 7 by the connecting pipe clasp 6, the right side of the first vacuum pipe 31 is connected with the left side of the vacuum control valve 32 by the clasp 17, the right side of the vacuum control valve 32 is connected with the left side of the second vacuum pipe 33 by the clasp 17, the right side of the second vacuum pipe 33 is connected with the left side of the vacuum filter 34 by the clasp 17, the right side of the vacuum filter 34 is connected with the left side of the third vacuum pipe 35 by the clasp 17, the right side of the third vacuum pipe 35 is connected with the defoaming vacuum pump 36 by the clasp 17, the first air pipe 22, the second air pipe 24, the third air pipe 26, the fourth air pipe 28, the fifth air pipe 210, the first vacuum pipe 31, the second vacuum pipe 33 and the third vacuum pipe 35 adopt a steel wire hose made of polytetrafluoroethylene material which is resistant to high temperature and can be sterilized, the clasp 17 is made of stainless steel which can be sterilized, the pressure display meter 1 is made of stainless steel which is resistant to high temperature, can be sterilized and resistant to corrosion, the pressure display meter 1 is provided with positive pressure and negative pressure display functions, can be sterilized at the terminal, reduces the difficulty of sterilization, the air filter 27 and the vacuum filter 34 can filter and purify the air in the air pipe and the vacuum pipe, remove impurities, purify the air, can not only eliminate the bubbles of collagen protein, but also ensure the final sterile state.

[0030] Working principle:

[0031] Before use, the processor is installed as a whole, and then high-temperature sterilization is performed. When sterilizing, the pressing plate is kept close to the top cover of the defoaming barrel 5, the air control valve 29, the vacuum control valve 32 and the discharge port 13 left and right two sides of the discharge port opening and closing valve 15 are opened, after sterilization, the vacuum control valve 32, the air control valve 29 and the discharge port opening and closing valve 15 on the left and right sides of the discharge port 13 are closed in the hundred-level laminar flow environment, the air compressor 21 and the defoaming vacuum pump 36 are opened, the vacuum control valve 32 is opened, the sterile collagen is transported into the defoaming barrel body 4 through the U-shaped feeding port 10, after the collagen is completely transported, the feeding port cover plate 9 is placed on the feeding port 10, the feeding port opening and closing valve 11 on the left and right sides of the feeding port 10 is closed, the vacuum control valve 32 is closed, the air control valve 29 is opened to make the pressing plate 8 lightly press on the collagen in the defoaming barrel body 4, the air control valve 29 is closed, the vacuum control valve 32 is opened, the pressure display 1 is observed, the production operator observes the defoaming condition of the collagen through the defoaming barrel body, adjusts the vacuum degree, when the liquid level in the defoaming barrel body no longer rises, the vacuum degree is kept at-50 kilopascals for 0.5-5 hours, the vacuum control valve 32 is closed, at this time, the defoaming barrel body 4 is in a negative pressure environment. The pressure regulating valve 23 is opened, the production operator controls the pressure through the pressure display 25, and the pressure is controlled at 0.1 megapascal, after the pressure is stable, the discharge port opening and closing valve 15 on the left and right sides of the discharge port 13 is opened, and the air control valve 29 is opened, so that the defoaming barrel body 4 is in a positive pressure environment, the pressing plate 8 in the defoaming barrel body 4 is pushed to extrude the collagen to be discharged through the discharge port, and the vacuum defoaming is completed.

[0032] It should be noted that, in the present document, relational terms such as first and second and the like can be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises", "comprising", or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but can include other elements not expressly listed or inherent to such process, method, article, or apparatus. An element proceeded by "comprises... a" does not, without more constraints, exclude the presence of additional identical elements in the process, method, article, or apparatus that comprises the element.

Claims

1. A medical grade collagen preparation vacuum defoaming processor, characterized by: The application relates to a processor support (16) provided with a defoaming barrel (4), the left side of the defoaming barrel (4) is provided with a feeding port (10) and a defoaming barrel handle (12), the bottom of the defoaming barrel (4) is provided with a discharging port (13), the right side of the defoaming barrel (4) is provided with a defoaming barrel handle (12), the upper side of the defoaming barrel (4) is provided with a defoaming barrel top cover (5), the defoaming barrel top cover (5) is provided with a connecting pipe (7), the upper side of the connecting pipe (7) is connected with a pressure display (1) through a connecting pipe clasp ring (6), the lower side of the connecting pipe (7) penetrates through the central shaft of the defoaming barrel top cover (5), the left side of the connecting pipe (7) is provided with an air assembly (2), and the right side of the connecting pipe (7) is provided with a vacuum assembly (3).

2. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The defoaming barrel (4) is made of high-temperature-resistant, sterilizable, transparent and visible polymethyl methacrylate or polypropylene material.

3. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The feeding port (10) is in a U shape, the upper end of the feeding port (10) is provided with a feeding port cover plate (9) which plays a sealing and bacteria-blocking role, and the feeding port cover plate (9) is fixedly connected with feeding port on-off valves (11) arranged on the left and right sides of the feeding port cover plate (9).

4. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The bottom of the discharging port (13) penetrates through the central shaft of the bottom end of the processor support (16), the discharging port (13) is provided with a discharging port cover plate (14) which plays a sealing and bacteria-blocking role, and the discharging port cover plate (14) is fixedly connected with discharging port on-off valves (15) arranged on the left and right sides of the discharging port cover plate (14).

5. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The defoaming barrel (4) is internally provided with a pressing plate (8), the thickness of the pressing plate (8) is 3-5 mm, the diameter of the pressing plate (8) is smaller than that of the defoaming barrel (4) by 0.5-1.5 mm, and the pressing plate (8) is made of medical-grade polypropylene material, polytetrafluoroethylene material or polyethylene terephthalate material which can be sterilized and is non-toxic.

6. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The pressure display (1) and a pressure display table (25) are made of high-temperature-resistant, sterilizable and corrosion-resistant stainless steel material, and the pressure display (1) is provided with positive pressure and negative pressure display functions.

7. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The defoaming barrel top cover (5) is made of sterilizable, high-temperature-resistant and corrosion-resistant stainless steel material, the defoaming barrel top cover (5) is fixedly connected with the defoaming barrel (4) through a defoaming barrel top cover clasp (52) which plays a sealing role, the defoaming barrel top cover clasp (52) is provided with a defoaming barrel top cover clasp switch (51), the connecting pipe (7) arranged on the defoaming barrel top cover (5) is in an integrated mode, and the connecting pipe (7) and the connecting pipe clasp ring (6) are made of sterilizable, high-temperature-resistant and corrosion-resistant stainless steel material.

8. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The air assembly (2) comprises an air compressor (21), a first air pipe (22), a pressure regulating valve (23), a second air pipe (24), a pressure display table (25), a third air pipe (26), an air filter (27), a fourth air pipe (28), an air control valve (29) and a fifth air pipe (210), the air compressor (21) is connected with the left side of the first air pipe (22) by a clasp ring (17), the right side of the first air pipe (22) is connected with the air inlet of the pressure regulating valve (23) by a clasp ring (17), the air outlet of the pressure regulating valve (23) is connected with the left side of the second air pipe (24) by a clasp ring (17), the right side of the second air pipe (24) is connected with the left side of the pressure display table (25) by a clasp ring (17), the right side of the pressure display table (25) is connected with the left side of the third air pipe (26) by a clasp ring (17), the right side of the third air pipe (26) is connected with the left side of the air filter (27) by a clasp ring (17), the right side of the air filter (27) is connected with the left side of the fourth air pipe (28) by a clasp ring (17), the right side of the fourth air pipe (28) is connected with the left side of the air control valve (29) by a clasp ring (17), the right side of the air control valve (29) is connected with the left side of the fifth air pipe (210) by a clasp ring (17), and the right side of the fifth air pipe (210) is connected with the connecting pipe (7) by a connecting pipe clasp ring (6); the pore size of the air filter (27) is 0.22 μm; the first air pipe (22), the second air pipe (24), the third air pipe (26), the fourth air pipe (28) and the fifth air pipe (210) are made of a steel wire hose made of polytetrafluoroethylene material which is resistant to high temperature and can be sterilized.

9. A vacuum defoaming processor for medical grade collagen preparation according to claim 1, characterized in that: The vacuum assembly (3) comprises a first vacuum pipe (31), a vacuum control valve (32), a second vacuum pipe (33), a vacuum filter (34), a third vacuum pipe (35) and a defoaming vacuum pump (36), the left side of the first vacuum pipe (31) is connected with the right side of the connecting pipe (7) by a connecting pipe clasp ring (6), the right side of the first vacuum pipe (31) is connected with the left side of the vacuum control valve (32) by a clasp ring (17), the right side of the vacuum control valve (32) is connected with the left side of the second vacuum pipe (33) by a clasp ring (17), the right side of the second vacuum pipe (33) is connected with the left side of the vacuum filter (34) by a clasp ring (17), the right side of the vacuum filter (34) is connected with the left side of the third vacuum pipe (35) by a clasp ring (17), the right side of the third vacuum pipe (35) is connected with the defoaming vacuum pump (36) by a clasp ring (17), and the clasp ring (17) is made of stainless steel material which can be sterilized; the pore size of the vacuum filter (34) is 0.22 μm; the first vacuum pipe (31), the second vacuum pipe (33) and the third vacuum pipe (35) are made of a steel wire hose made of polytetrafluoroethylene material which is resistant to high temperature and can be sterilized.

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