High-precision glycosylated hemoglobin detection kit
The glycated hemoglobin detection kit, with its snap-fit structure and shock-absorbing cotton design, solves the problems of long bottle cap operation time and inaccurate sample transfer in existing technologies, achieving a highly efficient and accurate detection process.
Patent Information
- Application Number
- CN202422963865.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-03
- Publication Date
- 2025-12-09
- Estimated Expiration
- 2034-12-03
AI Technical Summary
Existing glycated hemoglobin test kits suffer from threaded connections that cause time to be spent opening and closing the caps during emergency or frequent use, affecting testing efficiency. Furthermore, samples are prone to splashing or being lost during transfer, impacting test accuracy.
The dropper cap and sealing cone stopper with snap-fit structure allow for one-handed operation of the hemolysis reagent bottle. Combined with the design of anti-collision cotton and locking tongue, it ensures sealing and stability, and reduces sample error and external contamination.
It improves operational efficiency, ensures accurate sample volume, reduces sample splashing and contamination risks, and enhances the accuracy and stability of testing.
Smart Images
Figure CN223650425U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to a glycated hemoglobin detection kit technical field, specifically to a high accuracy glycated hemoglobin detection kit. BACKGROUND
[0002] The high accuracy glycated hemoglobin detection kit is mainly used for accurately measuring the content of glycated hemoglobin in a blood sample. Glycated hemoglobin is the product formed by the slow, irreversible non-enzymatic reaction of hemoglobin and glucose. Through the detection of the kit, the proportion of glycated hemoglobin in the blood can be accurately known. The detection result can reflect the average blood glucose level of the patient in the past 2-3 months, providing key data support for the diagnosis, treatment effect evaluation and disease monitoring of diabetes.
[0003] The reagent bottle and bottle cap inside the existing kit are usually connected in a threaded manner. In an emergency or frequent use situation, the threaded connection will take a lot of time, and more time is spent on rotating the bottle cap each time the hemolytic reagent bottle is opened and closed, affecting the detection efficiency. When the blood sample is transferred from the hemolytic reagent bottle to the reaction dish, the sample may easily splash or be lost, resulting in insufficient sample quantity and affecting the accuracy of the detection result.
[0004] Therefore, we designed a high accuracy glycated hemoglobin detection kit to solve the above problems. UTILITY MODEL CONTENTS
[0005] The utility model aims at providing a high accuracy glycated hemoglobin detection kit to solve the problems raised in the background art.
[0006] To solve the above technical problems, the utility model provides a high accuracy glycated hemoglobin detection kit, which comprises a kit body, a detection reagent bottle, a hemolytic reagent bottle and a sampling dropper are placed inside the kit body, a dropper cover is clamped at the opening of one end of the hemolytic reagent bottle, a sealing cone plug is fixedly connected to the side of the dropper cover close to the hemolytic reagent bottle, and a mixing dropper is integrally formed on the other side of the dropper cover.
[0007] Further, a sealing cap is installed at one end of the detection reagent bottle, a puncture needle is fixedly arranged on the inner end face of the groove at the other end of the sealing cap, a protective sleeve is sleeved on the outside of the sampling dropper, and a limiting ring is fixedly connected to the inner bottom of the protective sleeve.
[0008] Further, a positioning sponge layer is placed inside the kit body, a plurality of accommodating grooves are formed on the upper surface of the positioning sponge layer, and the detection reagent bottle, the hemolytic reagent bottle and the sampling dropper are all inserted into the accommodating grooves.
[0009] Further, the inside of the accommodating groove is also placed with a cuvette.
[0010] Further, the inner wall of the kit body flip cover is glued with the anti-collision cotton, the anti-collision cotton is bonded with the clamping block near one side of the kit body flip cover, the kit body flip cover is provided with the clamping groove near the side of the anti-collision cotton, and the clamping block and the clamping groove are clamped.
[0011] Further, the main body part of the kit body and the flip cover of the kit body are respectively provided with the lock catch and the lock tongue, and the lock catch and the lock tongue are clamped and connected.
[0012] Compared with the prior art, the kit has the advantages that:
[0013] 1. The hemolysis reagent bottle and the dropper cap are clamped, one-handed operation is realized, the hemolysis reagent bottle is opened and closed, operation time is saved, work efficiency is improved, the sealing cone plug can be tightly attached to the bottle opening of the hemolysis reagent bottle, leakage of the hemolysis reagent is prevented, the risk of contamination of the reagent is reduced, when the blood sample is mixed with the detection reagent, the mixing dropper can accurately control the output amount of the treated blood sample, and the sample is prevented from splashing out due to too fast flow, and errors possibly caused by intermediate links are reduced.
[0014] 2. The anti-collision cotton is accurately positioned through clamping of the clamping block and the clamping groove, displacement of the anti-collision cotton is prevented, and stability of the buffering effect is ensured. Meanwhile, the lock catch and the lock tongue on the main body part and the flip cover of the kit body are clamped and connected, a closed space is formed, dust, impurities and moisture in the outside are prevented from entering the kit body, and the accommodating groove reduces displacement of the articles during movement or shaking in the kit body. BRIEF DESCRIPTION OF DRAWINGS
[0015] Figure 1 It is a structural schematic view of the utility model;
[0016] Figure 2 It is a structural schematic view of the clamping block and the clamping groove of the utility model;
[0017] Figure 3 It is a structural schematic view of the utility model; Figure 1 It is an enlarged schematic view of position A in the utility model;
[0018] Figure 4 It is an enlarged schematic view of position B in the utility model; Figure 1
[0019] Figure 5 It is a sectional view of the protective sleeve of the utility model.
[0020] In the figure: 1, kit body; 2, positioning sponge layer; 3, containing groove; 4, detection reagent bottle; 5, sealing cover; 6, puncture needle; 7, hemolytic reagent bottle; 8, dropper cover; 9, mixing dropper; 10, anti-collision cotton; 11, clamping block; 12, clamping groove; 13, lock catch; 14, lock tongue; 15, protective sleeve; 16, sampling dropper; 17, limiting ring; 18, sealing cone plug; 19, cuvette. DETAILED DESCRIPTION
[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.
[0022] Please refer to Figures 1-5 The utility model provides a kind of technical solutions: a kind of high-precision glycated hemoglobin detection reagent kit, including kit body 1, reagent bottle 4, hemolytic reagent bottle 7, sampling dropper 16 are placed in kit body 1 inside detection reagent, sampling dropper 16 surface is equipped with scale, it is convenient for operator accurate control sampling amount.Hemolytic reagent is added in advance in reagent bottle 4 inside detection reagent, hemolytic reagent bottle 7 one end opening is connected with dropper cover 8, dropper cover 8 is fixedly connected with sealing cone plug 18 close to hemolytic reagent bottle 7 side, the other side of dropper cover 8 is integrally connected with mixing dropper 9.
[0023] In specific implementation, the rubber head part of the sampling dropper 16 is squeezed to generate negative pressure to suck the blood sample. During the sucking process, the amount of blood sucked is accurately controlled by observing the scale on the surface of the sampling dropper 16. Then the dropper cover 8 on the hemolytic reagent bottle 7 is opened, the sealing cone plug 18 is separated from the bottle opening of the hemolytic reagent bottle 7, and the blood sample is injected into the hemolytic reagent bottle 7. The hemolytic reagent in the hemolytic reagent bottle 7 breaks the cell membrane of red blood cells and releases glycated hemoglobin therein. Then the dropper cover 8 is closed and shaken evenly. Finally, the treated blood sample is output through the mixing dropper 9. This process is convenient to operate and can ensure the accuracy of sampling, while avoiding the loss of reagents during transfer, effectively improving the accuracy of subsequent detection values.
[0024] Please refer to Figures 1-5As shown, the end of the test reagent bottle 4 is buckled with a sealing cover 5, the other end of the sealing cover 5 is fixedly provided with a puncture needle 6 in the recessed inner end face, which is used to pierce the mixing dropper 9 to mix the reagent, the sampling dropper 16 is sleeved with a protective sleeve 15, the protective sleeve 15 is fixedly connected with a limiting ring 17 at the bottom, which is used to protect the sampling dropper 16, when the reagent box moves or is slightly shaken, the limiting ring 17 protects the stability of the sampling dropper 16 inside the protective sleeve 15, prevents the sampling dropper 16 from colliding with the inner wall of the protective sleeve 15 and being damaged, and avoids the scale of the sampling dropper 16 from being worn to cause misreading.
[0025] Referring to Figures 1-5 , the inside of the reagent box body 1 is placed with a positioning sponge layer 2, a plurality of accommodating grooves 3 are opened on the upper surface of the positioning sponge layer 2, the test reagent bottle 4, the hemolytic reagent bottle 7, and the sampling dropper 16 are inserted into the accommodating grooves 3. The inside of the accommodating groove 3 is also placed with a cuvette 19, which reduces the risk of damage of the test reagent bottle 4, the hemolytic reagent bottle 7, the sampling dropper 16, and the cuvette 19 due to shaking, and improves the stability inside the reagent box body 1.
[0026] Referring to Figures 1-5 , the inner wall of the lid of the reagent box body 1 is glued with an anti-collision cotton 10, when the lid of the reagent box body 1 is closed, the anti-collision cotton 10 can play a buffering role, reducing the collision between the lid and the test reagent bottle 4, the hemolytic reagent bottle 7, the sampling dropper 16, and the cuvette 19 inside the main part of the reagent box body 1, the side of the anti-collision cotton 10 close to the lid of the reagent box body 1 is bonded with a clamping block 11, the side of the lid of the reagent box body 1 close to the anti-collision cotton 10 is provided with a clamping groove 12, the clamping block 11 and the clamping groove 12 are clamped to be accurately positioned, preventing the displacement of the anti-collision cotton 10, the main part of the reagent box body 1 and the lid of the reagent box body 1 are respectively provided with a lock catch 13 and a lock tongue 14, the lock catch 13 and the lock tongue 14 are clamped and connected, preventing the outside dust, impurities, and moisture from entering the inside of the reagent box body 1, and preventing the reagent box body 1 from being accidentally opened.
[0027] Working principle: By squeezing the rubber head part of the sampling dropper 16 to generate negative pressure, the blood sample is sucked. During the suction process, the amount of blood sucked is accurately controlled by observing the scale on the surface of the sampling dropper 16. Then open the dropper cover 8 on the hemolysis reagent bottle 7, the sealing cone plug 18 is separated from the bottle mouth of the hemolysis reagent bottle 7, and the blood sample is injected into the hemolysis reagent bottle 7, the hemolysis reagent in the hemolysis reagent bottle 7 destroys the cell membrane of red blood cells, releases the glycosylated hemoglobin in it, and then covers the dropper cover 8 for shaking. The puncture needle 6 pierces one end of the mixing dropper 9, and the treated blood sample is injected into the cuvette 19 through the mixing dropper 9. Open the test reagent bottle 4, and inject the test reagent into the cuvette 19. At this time, the test reagent reacts with the glycosylated hemoglobin, and the color of the mixed reaction liquid will change. By emitting a specific wavelength of light through the reaction liquid in the cuvette 19, the change in absorbance can be detected, and the concentration of glycosylated hemoglobin in the sample can be calculated.
[0028] The accommodation groove 3 on the positioning sponge layer 2 is used to place the test reagent bottle 4, the hemolysis reagent bottle 7, the sampling dropper 16 and the cuvette 19. The accommodation groove 3 reduces the displacement of these items during the movement or shaking of the kit body 1, thereby reducing the risk of damage caused by mutual collision or collision with the inner wall of the kit body 1. When the kit body 1 is closed, the anti-collision cotton 10 in the inner wall of the flap plays a buffering role, reducing the collision between the flap and the internal items. The anti-collision cotton 10 is precisely positioned by the clamping block 11 and the clamping groove 12, preventing displacement and ensuring the stability of the buffering effect. At the same time, the lock catch 13 and the lock tongue 14 on the main body part and the flap of the kit body 1 are connected, forming a closed space to prevent external dust, impurities and moisture from entering the kit, and to avoid accidental opening of the kit body 1, protecting the internal reagents and tools from external factors interference and damage.
Claims
1. A high-precision glycated hemoglobin test kit comprising a kit body (1), characterized in that, The reagent box (1) internally places detection reagent bottle (4), hemolytic reagent bottle (7), sampling dropper (16), one end of hemolytic reagent bottle (7) is clamped with dropper cover (8), dropper cover (8) is fixedly connected with sealing cone plug (18) on one side close to hemolytic reagent bottle (7), the other side of dropper cover (8) is integrally connected with mixing dropper (9).
2. The high-precision glycated hemoglobin test kit according to claim 1, characterized in that: The detection reagent bottle (4) is clamped with sealing cover (5) at one end, the sealing cover (5) is fixedly provided with puncture needle (6) on the inner end face of the other end groove, the sampling dropper (16) is sleeved with protective sleeve (15) outside, the protective sleeve (15) is fixedly connected with limiting ring (17) in the bottom.
3. The high precision glycated hemoglobin test kit according to claim 1, wherein the antibody is an antibody recognizing the N-terminal of the glycated hemoglobin. The reagent box (1) internally places positioning sponge layer (2), the upper surface of positioning sponge layer (2) is provided with a plurality of containing grooves (3), detection reagent bottle (4), hemolytic reagent bottle (7) and sampling dropper (16) are all inserted into containing groove (3). 4. The high precision glycated hemoglobin test kit according to claim 3, wherein the antibody is an antibody against glycated hemoglobin. The inside of containing groove (3) also places cuvette (19).
5. The high precision glycated hemoglobin test kit according to claim 3, wherein the antibody is an antibody against glycated hemoglobin. The inner wall of the lid of reagent box (1) is glued with anti-collision cotton (10), the side close to reagent box (1) of anti-collision cotton (10) is bonded with clamping block (11), the side close to anti-collision cotton (10) of the lid of reagent box (1) is provided with clamping groove (12), clamping block (11) and clamping groove (12) are clamped.
6. A high precision glycated hemoglobin test kit according to claim 5, wherein the antibody is an antibody against glycated hemoglobin. The main body part of reagent box (1) and the lid of reagent box (1) are respectively provided with lock catch (13) and lock tongue (14), lock catch (13) and lock tongue (14) are clamped.