Kit for detecting endometrial cancer

Abstract

The utility model relates to an endometrial cancer detection kit which comprises a kit body, a kit cover is movably connected to one side of the top of the kit body, the kit body and the kit cover are connected through a buckle, a first limiting plate is installed at the bottom in the kit body, a limiting groove is formed in the middle of the upper surface of the first limiting plate, and a reagent shelf is installed in the kit body and located above the first limiting plate. A plurality of reagent grooves for mounting reagent tubes are formed in the reagent shelf, and a microwell plate is also placed in the middle of the upper surface of the reagent shelf; the plurality of reagent tubes are used for storing an enzyme marker, a chromogenic substrate, a sample diluent, a washing buffer solution, a positive reference substance and a negative reference substance. According to the endometrial cancer detection kit, safe storage and transportation of reagents can be ensured, the detection convenience, accuracy and reliability are improved, and powerful support is provided for early diagnosis of endometrial cancer.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical detection equipment field, concretely relates to a reagent box for endometrial carcinoma detection. BACKGROUND

[0002] Endometrial carcinoma is one of the common malignant tumors of female reproductive system, and its incidence rate shows an upward trend in the global scope. Early and accurate diagnosis is crucial for improving the cure rate and survival rate of patients. At present, although the methods for endometrial carcinoma detection in clinic are various, they all have different degrees of limitations.

[0003] Traditional diagnostic curettage, although is the "gold standard" of diagnosis, but it belongs to invasive operation, can bring great pain to patients, and has certain complication risk, such as uterine perforation, hemorrhage, etc. In addition, the technical requirement of the method for operating personnel is higher, and the diagnostic result can also appear misdiagnosis or missed diagnosis due to incomplete curettage or sample selection deviation.

[0004] Although ultrasonic examination is simple and convenient to operate, it is non-invasive, but the specificity and sensitivity for the diagnosis of early endometrial carcinoma are relatively low, especially for the detection ability of some small lesions, which is easy to lead to missed diagnosis of early lesions.

[0005] Tumor marker detection as a relatively non-invasive detection method has received extensive attention in recent years. However, the existing endometrial carcinoma detection reagent box has many problems in actual use due to unreasonable structure design, such as the reagent tube is easy to shake and collide in the reagent box, which may cause reagent leakage or deterioration, and affect the accuracy of the detection result. At the same time, the existing reagent box often lacks effective control of temperature, and some temperature-sensitive reagents may lose activity in different environments, further reducing the reliability of detection. In addition, the overall protection performance of the reagent box is insufficient, and the internal detection instruments such as microplate are easy to be damaged when subjected to certain external impact, which limits the wide application of the reagent box in clinical detection. UTILITY MODEL CONTENTS

[0006] The utility model mainly aims at the above problems existing in the prior art, provides a reagent box for endometrial carcinoma detection, ensures the safe storage and transportation of reagents, and improves the convenience and accuracy of the detection process, so as to meet the needs of efficient and reliable detection of endometrial carcinoma in clinic.

[0007] The purpose of the utility model is mainly realized through the following scheme:

[0008] The utility model provides a kit for endometrial carcinoma detection, including the box body, the top side of box body is connected with the box cover, and is connected through the buckle between box body and box cover, the first limit board is installed in the bottom of box body, the upper surface middle part of first limit board is equipped with the limit groove, the reagent rack is installed in the top of first limit board in the box body, a plurality of reagent grooves for installing reagent tube are set up on the reagent rack, and the upper surface middle part of reagent rack also places the microwell plate, the reagent tube is equipped with a plurality of, is used to store enzyme marker, color developing substrate, sample diluent, washing buffer, positive control and negative control.

[0009] As preferred, the reagent rack comprises an upper limiting disc, a lower limiting disc and a limiting column connected between the upper limiting disc and the lower limiting disc, and a plurality of reagent grooves are uniformly circumferentially arranged on the upper limiting disc along the axis thereof.

[0010] As preferred, the number of the reagent grooves is 6-20.

[0011] As preferred, the upper surface of the lower limiting disc is provided with a limiting cylinder with an open top at a position corresponding to the reagent groove, and the lower end of the reagent tube is inserted into the limiting cylinder.

[0012] As preferred, the lower surface of the lower limiting disc is provided with a limiting rod adapted to the limiting groove in the middle part, and the limiting rod is inserted into the limiting groove.

[0013] As preferred, the inner wall of the limiting cylinder and the upper surface of the first limiting plate are both provided with a buffer layer.

[0014] As preferred, there is a gap between the reagent rack and the inner wall of the box body, and a refrigeration group is placed in the gap.

[0015] As preferred, the back surface of the box cover is provided with a buffer pad.

[0016] Therefore, compared with the prior art, the utility model has the following advantages:

[0017] (1) The buffer layer on the inner wall of the limiting cylinder and the upper surface of the first limiting plate, and the buffer pad on the back surface of the box cover, so that the reagent tube is protected in all directions in the reagent box, greatly reducing the risk of leakage and damage caused by shaking and collision of the reagent tube during transportation and storage, ensuring that the reagent performance is not affected, thereby improving the accuracy and reliability of the detection results.

[0018] (2) The reagent grooves uniformly circumferentially arranged on the upper limiting disc and the microwell plate in the middle part of the upper surface of the upper limiting disc, so that various reagents and microwell plates have a clear position in the box body, are easy to access, reduce the operation errors in the detection process, and improve the detection efficiency.

[0019] (3) The utility model discloses a refrigeration unit is set up, the temperature in the box body can be effectively controlled, meet the storage demand of temperature sensitive reagent, broaden the application range and storage condition of reagent box, further improve the stability and reliability of detection.

[0020] (4) The utility model discloses a buckle is connected box body and box cover, and the user is convenient to open and close reagent box fast, improved the convenience of operation. DRAWINGS

[0021] Figure 1 It is a structural schematic diagram of the utility model,

[0022] Figure 2 It is a side view of the utility model,

[0023] Figure 3 It is the exploded schematic diagram of the utility model,

[0024] Figure 4 It is the structural schematic diagram of reagent frame in the utility model.

[0025] Illustration: 1-box body, 2-box cover, 3-buckle, 4-first limit board, 5-limit slot, 6-reagent frame, 7-reagent tube, 8-reagent groove, 9-microplate, 10-upper limit disc, 11-lower limit disc, 12-limit column, 13-limit cylinder, 14-limit rod, 15-clearance, 16-cushion. DETAILED DESCRIPTION

[0026] The technical scheme of the utility model will be further explained in detail below by specific embodiments, and in conjunction with the drawings. It should be understood that the implementation of the utility model is not limited to the following examples, and any form of variation and / or change of the utility model will fall within the scope of protection of the utility model.

[0027] In the utility model, if not specified, all parts, percentages are weight units, and the equipment and raw materials used can be purchased from the market or commonly used in the art. The methods in the following examples are conventional methods in the art unless otherwise specified. The components or equipment in the following examples are general standard components or components known to those skilled in the art unless otherwise specified. Their structure and principle are known to the skilled person through technical manuals or conventional experimental methods.

[0028] Example 1:

[0029] As Figure 1As shown, the utility model provides a technical scheme, endometrial carcinoma detection kit, including top opening, inside hollow box body 1, the rear side of top of box body 1 is hingedly connected with box cover 2, and box body 1 is tightly connected with box cover 2 through buckle 3, and the edge between box body 1 and box cover 2 is bonded with sealing ring, guarantee the sealing property of box body 1 in the transportation and storage process, prevent the impurity such as external dust, moisture and so on from entering and influence reagent performance.

[0030] As Figure 3 Shown, the inside bottom central portion of above-mentioned box body 1 is bonded or bolted with first limit plate 4, the upper surface middle portion of first limit plate 4 is provided with limit slot 5, reagent rack 6 is installed in the upper side of first limit plate 4 in box body 1, and limit slot 5 is mainly used for accurate positioning of upper reagent rack 6, a plurality of reagent slots 8 for installing reagent tube 7 are provided on reagent rack 6, and the upper surface middle portion of reagent rack 6 is provided with recess, and microplate 9 is placed in recess; specifically, as Figure 4 Shown, reagent rack 6 includes upper limit disc 10, lower limit disc 11 and limit column 12 fixedly connected between upper limit disc 10 and lower limit disc 11, reagent slot 8 is evenly circumferentially provided along the axis of upper limit disc 10, and the number of reagent slot 8 is 6-20, which can be flexibly adjusted according to actual reagent type and use demand, these reagent slots 8 are used for closely installing and storing various reagents reagent tube 7, for storing enzyme marker, color developing substrate, sample diluent, washing buffer, positive control and negative control, 15 reagent slots 8 are provided in the embodiment, which are respectively 3 groups of enzyme markers, 3 groups of color developing substrates, 3 groups of sample diluents, 2 groups of washing buffers, 2 groups of positive controls and 2 groups of negative controls, and a label showing reagent type is attached to one side of each reagent slot 8.

[0031] Example 2:

[0032] As Figure 1 , 4 Shown, the utility model provides another technical scheme, endometrial carcinoma detection kit, which is different from example 1, the upper surface of above-mentioned lower limit disc 11 is bonded with limit cylinder 13 with top opening at the position corresponding to reagent slot 8, and the lower end of reagent tube 7 is inserted into the inside of limit cylinder 13, so that reagent tube 7 is doubly limited from the top and bottom directions, effectively preventing the shaking and collision of reagent tube 7 during transportation.

[0033] Specifically, the lower surface middle portion of lower limit disc 11 is fixedly connected with limit rod 14 matched with limit slot 5, limit rod 14 can be accurately inserted into limit slot 5, further ensuring the stability of reagent rack 6 in box body 1, preventing displacement.

[0034] Specifically, in order to further protect the reagent tube 7 and other internal components, the inner wall of the limiting cylinder 13 and the upper surface of the first limiting plate 4 are provided with a buffer layer, which can be made of soft and good buffering material, such as silica gel, sponge, etc., which can effectively absorb the vibration and impact force generated during transportation, and avoid the reagent tube 7 from being broken due to collision.

[0035] Specifically, as shown in Figure 2 The back of the box cover 2 is attached with a buffer pad 16, which can buffer and protect the microplate 9 and the reagent tube 7 on the reagent rack 6 when the box cover 2 is closed.

[0036] Example 3:

[0037] As shown in Figure 1 The utility model provides another technical scheme, the reagent kit for endometrial carcinoma detection, and the difference from example 1 is that there is gap 15 between the reagent rack 6 and the inner wall of box body 1, and a refrigeration group (not shown in the figure) is placed in the gap 15, and the specific refrigeration group can adopt small-sized refrigeration equipment such as semiconductor refrigerating sheet, which can accurately regulate the temperature in the box according to actual demand, ensure that the reagent is always in the suitable storage temperature environment, effectively prolong the shelf life and stability of the reagent, if semiconductor refrigerating sheet is adopted, the sidewall of box body 1 should be provided with through hole for semiconductor refrigerating sheet to dissipate heat, and the semiconductor refrigerating sheet is prior art, which can be powered by storage battery, and the specific structure and circuit connection are not within the protection scope of the application, and the person skilled in the art can deduce it, and here will not be repeated, in addition, the refrigeration group can also adopt ice crystal box, when the ice crystal box is used, a circle of protective plate can be arranged on the periphery of reagent rack 6, and the ice crystal box is located between the protective plate and the inner side of box body 1, so as to avoid the ice crystal box from colliding with the reagent tube 7.

[0038] The reagent kit for endometrial carcinoma detection provided by the utility model is protected all-round by the buffer layer arranged on the inner wall of the limiting cylinder 13 and the upper surface of the first limiting plate 4 and the buffer pad 16 on the back of the box cover 2, the risk of leakage and damage of the reagent tube caused by shaking and collision during transportation and storage is greatly reduced, the performance of the reagent is ensured not to be affected, thereby the accuracy and reliability of the detection result are improved, the reagent tank 8 arranged on the upper limiting disc 10 in uniform circumference and the microplate 9 located in the middle of the upper surface of the upper limiting disc 10 make various reagents and the microplate 9 have definite positions in the box body 1 and be easy to take, operation mistakes in the detection process are reduced, and the detection efficiency is improved, the refrigeration group ensures that the temperature in the box body 1 can be effectively controlled, the storage demand of the temperature-sensitive reagent is met, the application range and storage condition of the reagent kit are widened, and the stability and reliability of the detection are further improved, the box body 1 and the box cover 2 are connected by the buckle 3, the user can quickly open and close the reagent kit, and the convenience of operation is improved.

[0039] It should be understood that the embodiments are only used for illustrating the present application and not used for limiting the scope of the present application. In addition, it should be understood that after reading the content taught by the present application, those skilled in the art can make various changes or modifications to the present application, and these equivalent forms also fall within the scope defined by the claims of the present application.

Claims

1. A reagent kit for detecting endometrial cancer, comprising a box body (1), wherein a lid (2) is movably connected to one side of the top of the box body (1), and the box body (1) and the lid (2) are connected by a snap fastener (3), characterized in that: The bottom of the box (1) is equipped with a first limiting plate (4), and a limiting groove (5) is opened in the middle of the upper surface of the first limiting plate (4). A reagent rack (6) is installed in the box (1) above the first limiting plate (4). The reagent rack (6) has multiple reagent slots (8) for installing reagent tubes (7), and a microplate (9) is also placed in the middle of the upper surface of the reagent rack (6). Multiple reagent tubes (7) are provided for storing enzyme markers, chromogenic substrates, sample diluents, washing buffers, positive controls and negative controls.

2. The reagent kit for detecting endometrial cancer according to claim 1, characterized in that: The reagent rack (6) includes an upper limit plate (10), a lower limit plate (11), and a limiting post (12) connecting the upper limit plate (10) and the lower limit plate (11). Multiple reagent slots (8) are evenly circumferentially formed on the upper limit plate (10) along its axis.

3. The reagent kit for detecting endometrial cancer according to claim 2, characterized in that: The number of reagent tanks (8) is 6-20.

4. The endometrial cancer detection kit according to claim 3, characterized in that: The upper surface of the lower limiting plate (11) is provided with a limiting cylinder (13) with a top opening at the position corresponding to the reagent tank (8), and the lower end of the reagent tube (7) is inserted into the inside of the limiting cylinder (13).

5. The reagent kit for detecting endometrial cancer according to claim 4, characterized in that: The lower limit plate (11) has a limit rod (14) adapted to the limit groove (5) in the middle of its lower surface. The limit rod (14) is inserted into the limit groove (5).

6. The reagent kit for detecting endometrial cancer according to claim 5, characterized in that: The inner wall of the limiting cylinder (13) and the upper surface of the first limiting plate (4) are both provided with a buffer layer.

7. The reagent kit for detecting endometrial cancer according to claim 1, characterized in that: There is a gap (15) between the reagent rack (6) and the inner wall of the box (1), and a refrigeration unit is placed in the gap (15).

8. The reagent kit for detecting endometrial cancer according to claim 1, characterized in that: The back of the lid (2) is provided with a cushioning pad (16).

Images