Middle plate assembly, packaging box, automatic pipetting device and pipetting suction head

Abstract

The utility model provides a middle plate assembly, a packaging box, an automatic pipetting device and a pipetting suction head, and relates to the technical field of medical equipment. The middle plate assembly comprises a middle plate, the middle plate is provided with a plurality of suction head inserting holes and a positioning part, the middle plate assembly further comprises a lining box, the lining box is provided with a connecting end, the connecting end is provided with a lining box opening, and the back face of the middle plate is connected with the connecting end of the lining box to seal the lining box opening. The ends, located on the back face, of the suction head insertion holes are located in the covering range of the opening of the lining box. And the positioning part is positioned outside the lining box, so that the middle plate can be positioned and matched with the carrying frame. By improving the middle plate for bearing the suction head, the risk that the suction head is polluted can be reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical equipment, in particular to a middle plate assembly, a packaging box, an automatic pipetting device and a pipetting tip. BACKGROUND

[0002] In the automatic pipetting device, the disposable tip is a basic experimental consumable. At present, the method for using the consumable is to take the consumable out of the packaging box, and then place the middle plate with the tip in the corresponding carrier for operation and use by the mechanical arm in the instrument. However, the tip is in a bare state on the carrier of the equipment loading table, which is easy to cause the tip to be contaminated. CONTENT OF THE UTILITY MODEL

[0003] Therefore, the purpose of the present application is to overcome the deficiencies in the prior art, and provide a middle plate assembly, a packaging box, an automatic pipetting device and a pipetting tip. By improving the middle plate carrying the tip, the risk of the tip being contaminated can be reduced.

[0004] The present application provides the following technical solutions:

[0005] In a first aspect, the present application provides a middle plate assembly, which comprises a middle plate having a plurality of tip insertion holes and a positioning portion, and further comprises:

[0006] an inner liner box having a connecting end with an inner liner box opening, the back surface of the middle plate and the connecting end of the inner liner box are connected to close the inner liner box opening, and the plurality of tip insertion holes located at one end of the back surface are within the coverage range of the inner liner box opening; wherein the positioning portion is located outside the inner liner box, so that the middle plate can be positioned and matched with the carrier.

[0007] In some embodiments of the first aspect, the back surface of the middle plate and the connecting end of the inner liner box are detachably connected.

[0008] In some embodiments of the first aspect, the connecting end and the middle plate are clamped, and the end surface of the connecting end and the back surface are arranged in parallel, and the end surface of the connecting end and the back surface are in abutment.

[0009] In some embodiments of the first aspect, the connecting end has at least two clamping tongues, the middle plate has at least two clamping grooves, the at least two clamping tongues are arranged at intervals along the circumference of the inner liner box opening, the at least two clamping grooves and the at least two clamping tongues are arranged one-to-one, and the clamping tongue and the corresponding clamping groove are clamped and matched.

[0010] In some embodiments of the first aspect, the clamping tongue is arranged in the corresponding clamping groove, so that a clamping force is formed between the inner wall of the clamping groove and the outer wall of the clamping tongue.

[0011] In some embodiments of the first aspect, at least a portion of the inner liner box in contact with the back surface is configured as a flexible portion or an elastic portion, so that the end surface of the connecting end can be deformed to fit the back surface.

[0012] In some embodiments of the first aspect, the connecting end has a flange, and the end surface of the flange abuts against the back surface.

[0013] In some embodiments of the first aspect, the inner liner box has a height direction, the side wall of the inner liner box is provided with a plurality of reinforcing ribs, the reinforcing ribs are arranged along the height direction, the connecting end is located at the top of the inner liner box, and the reinforcing ribs are formed by inwardly recessing the side wall of the inner liner box.

[0014] In a second aspect, the present application further provides a packaging box applied to the middle plate assembly according to any one of the above embodiments, and the packaging box comprises:

[0015] an outer liner box having an outer liner box opening, the outer liner box opening forming an access channel for the middle plate assembly to access the outer liner box, and a cover plate detachably arranged at the outer liner box opening to close the outer liner box opening.

[0016] In a third aspect, the present application further provides an automated pipetting device comprising the middle plate assembly according to any one of the above embodiments.

[0017] In a fourth aspect, the present application further provides a pipette tip adapted to the middle plate assembly according to any one of the above embodiments, and the pipette tip comprises a pipette body, the pipette body being arranged in the tip receptacle, the pipette body having a connecting end and a liquid suction end, the inner wall of the connecting end being provided with at least two sealing rings, the at least two sealing rings being arranged at intervals in the axial direction of the pipette body, and in any two adjacent sealing rings, the inner diameter of the sealing ring closer to the liquid suction end is smaller than the inner diameter of the sealing ring farther away from the liquid suction end.

[0018] Embodiments of the present application have the following advantages:

[0019] The present application provides a middle plate assembly, and the inner liner box is added to cooperate with the middle plate, which effectively reduces the time of the tip being exposed to the outside and reduces the risk of contamination. Moreover, the positioning portion is provided to ensure good compatibility of the middle plate assembly with the automated pipetting device, without affecting the normal use of the middle plate and the carrier, thereby improving the operation efficiency. The present application is especially suitable for laboratory environments with high precision and low contamination requirements, such as biomedical research, clinical diagnosis, etc. By reducing the contamination of the tip, the accuracy of the experimental results can be improved, and the cost of experimental failure or repeated experiments caused by contamination can be reduced.

[0020] In order to make the above objectives, features and advantages of the present application more obvious and easy to understand, the following preferred embodiments are described in detail below, and the accompanying drawings are described as follows. BRIEF DESCRIPTION OF DRAWINGS

[0021] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiments. It should be understood that the following drawings only show some embodiments of the present application, and therefore should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0022] Figure 1 A perspective view of a structure of a middle plate assembly is shown.

[0023] Figure 2 A perspective view of a structure of a middle plate of a middle plate assembly is shown.

[0024] Figure 3 A perspective view of a structure of an inner lining box of a middle plate assembly is shown.

[0025] Figure 4 A perspective view of a structure of a packaging box is shown.

[0026] Figure 5 A perspective view of an assembly structure of a packaging box and a middle plate assembly is shown.

[0027] Figure 6 Another perspective view of an assembly structure of a packaging box and a middle plate assembly is shown.

[0028] Figure 7 A perspective view of a structure of a pipette tip is shown.

[0029] Figure 8 Another perspective view of a structure of a pipette tip is shown.

[0030] Figure 9 A partial enlarged view of A in Figure 8

[0031] Explanation of main element symbols:

[0032] 100-middle plate; 110-card slot; 120-tip insertion hole; 130-positioning part; ​

[0033] 200 - inner box; 210 - flange; 220 - tab; 230 - reinforcing rib; 240 - connecting end;

[0034] 300 - package box; 310 - cover plate; 320 - outer box;

[0035] 400 - pipette body; 410 - connecting end; 411 - sealing ring; 420 - liquid suction end; 430 - filter core;

[0036] X - height direction. DETAILED DESCRIPTION

[0037] Embodiments of the present application are described in detail below with reference to the attached drawing figures, wherein the same or like reference numerals and characters throughout the figures denote the same or like elements or features. The embodiments described below are exemplary, and are not intended to be limiting.

[0038] It is noted that, when an element such as a layer, film, region, or substrate is referred to as being "on" another element, it can be directly on the other element or intervening elements can also be present. In contrast, when an element is referred to as being "directly on" another element, there are no intervening elements present. Like numbers refer to like elements throughout the specification. As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.

[0039] In the present application, unless otherwise explicitly specified and limited, the terms "mounting", "connecting", "connecting", "fixing" and the like should be understood in a broad sense, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art, the specific meaning of the above-mentioned terms in the present application can be understood according to the specific circumstances.

[0040] In addition, the terms "first", "second", "third" and the like are used only to describe purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined with "first", "second" can explicitly or implicitly include one or more of the features. In the description of the present application, the meaning of "multiple" is two or more, unless otherwise explicitly specified and limited.

[0041] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the templates herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the present application. As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.

[0042] In the related art, in an automated pipetting device, a disposable tip is a basic experimental consumable. Currently, the method of using the consumable is to take the consumable out of the packaging box, and then place the middle plate with the tips in the corresponding carrier for operation by the mechanical arm in the instrument. However, the tips are in a bare state on the carrier of the equipment loading table, which is easy to cause contamination of the tips.

[0043] As shown in Figure 1 , Figure 2 and Figure 3 , in order to solve the above technical problems, the embodiments of the present application provide a middle plate assembly, which comprises a middle plate 100 having a plurality of tip insertion holes 120 and a positioning part 130, and further comprises an inner liner box 200 having a connecting end 240 with an inner liner box 200 opening, the back surface of the middle plate 100 and the connecting end 240 of the inner liner box 200 are connected to close the inner liner box 200 opening, and the plurality of tip insertion holes 120 located at one end of the back surface are within the coverage range of the inner liner box 200 opening; wherein the positioning part 130 is located outside the inner liner box 200, so that the middle plate 100 can be positioned and matched with the carrier.

[0044] In these embodiments, the technical solution provided by the present application is an innovative solution to the problem of contamination of disposable tips in an automated pipetting device. By designing an improved middle plate assembly, the assembly not only includes a traditional middle plate 100 (for fixing tips), but also adds an inner liner box 200 design, effectively protecting the tips from contamination by the external environment. It should be noted that the positioning part 130 of the middle plate 100 can be adapted to the carrier to achieve positioning between the two, which is beneficial to the subsequent pipetting of the pipetting mechanical arm of the automated pipetting device. Wherein, the present application does not involve improving the cooperation between the positioning part 130 and the carrier, and the positioning cooperation between the positioning part 130 and the carrier is a routine setting for those skilled in the art, which will not be described here.

[0045] The inner liner box 200 in the middle plate assembly has a connecting end 240 with an inner liner box 200 opening, which is in communication with the inner cavity of the inner liner cavity. The back surface of the middle plate 100 is connected to the connecting end 240, thereby closing the opening of the inner liner box 200. The advantage of this is that a relatively closed space can be formed, reducing the opportunity for the tips to come into contact with the outside world, thereby reducing the possibility of contamination.

[0046] The plurality of tip sockets 120 are located on the back of the middle plate 100, and the positions of the sockets are within the coverage of the opening of the inner liner box 200. This means that when the tips are inserted into the sockets, they will be surrounded by the inner liner box 200 to isolate them from the outside world. In simple terms, when the tips are inserted into the tip sockets 120, the tip ends are located inside the inner liner box 200, and the tip sockets 120 are sealed by the tips, thereby enabling the inner cavity of the inner liner box 200 to form a relatively sealed ring 411 to isolate the tip ends from the outside world.

[0047] Obviously, the positioning part 130 is arranged outside the inner liner box 200, ensuring that the middle plate 100 can be accurately matched with the carrier. This design not only ensures the safety of the tips, but also does not affect their normal use in the automated pipetting device.

[0048] For example, the positioning part 130 is a positioning plate on both sides of the back of the middle plate 100. When the middle plate 100 is installed on the carrier, the positioning plate abuts against the side wall of the corresponding side of the carrier, thereby achieving positioning. That is, the positioning part 130 is arranged away from the inner liner box 200 to ensure the normal use of the positioning part 130. Of course, in other embodiments, the positioning part 130 can also be a positioning pin, and the carrier is provided with a positioning pin hole matched with the positioning pin.

[0049] For ease of understanding, generally, the carrier is provided with a receiving opening, and when the middle plate 100 is assembled on the carrier, the heads of the tips on the middle plate 100 are located in the receiving opening. The size of the inner liner box 200 arranged in the present application is designed to be capable of being accommodated in the receiving opening, so as to ensure that the middle plate 100 and the carrier can be normally matched and used, and the modification is small, and the original carrier can be used.

[0050] Therefore, the present application additionally provides the inner liner box 200 for use with the middle plate 100, which effectively reduces the time during which the tips are exposed to the outside world and reduces the risk of contamination. Moreover, the arrangement of the positioning part 130 ensures good compatibility of the middle plate assembly with the automated pipetting device, does not affect the normal use of the middle plate 100 and the carrier, and improves the operation efficiency. It is especially suitable for laboratory environments with high precision and low contamination requirements, such as biomedical research, clinical diagnosis, etc. By reducing the contamination of the tips, the accuracy of the experimental results can be improved, and the cost of experimental failure or repeated experiments caused by contamination can be reduced.

[0051] As shown in FIG. 1, Figure 1 In some embodiments, the back of the middle plate 100 and the connecting end 240 of the inner liner box 200 are detachably connected.

[0052] In these embodiments, the back of the middle plate 100 and the connecting end 240 of the inner liner box 200 are detachably connected, which brings more flexibility and convenience to the middle plate assembly.

[0053] For example, the middle plate 100 and the inner liner box 200 can be quickly connected and separated by designing a buckle structure of a specific shape. This method is simple to operate and does not require additional tools. In detail, the back surface of the middle plate 100 is provided with a plurality of protruding buckles, and the connecting end 240 of the inner liner box 200 is provided with corresponding grooves. The middle plate 100 is aligned with the inner liner box 200, and the two are connected by gently pressing. When disassembled, the middle plate 100 can be easily separated by gently pressing and rotating.

[0054] For example, magnets are installed on the middle plate 100 and the inner liner box 200 respectively, and the connection is realized by magnetic force. This method is stable and easy to disassemble. In detail, the back surface of the middle plate 100 and the connecting end 240 of the inner liner box 200 are respectively embedded with small magnets. The middle plate 100 is close to the inner liner box 200, and the magnetic force will automatically attract the two to tightly combine. When disassembled, the two can be separated by applying a slight force.

[0055] For example, the middle plate 100 and the inner liner box 200 are fixed together by screws or bolts. Although this method requires additional tools, the connection is more secure. In detail, the back surface of the middle plate 100 is provided with threaded holes, and the connecting end 240 of the inner liner box 200 is provided with corresponding studs. The middle plate 100 is aligned with the inner liner box 200, and the two are fixed by tightening the screws or bolts. When disassembled, the screws or bolts are unscrewed in reverse.

[0056] For example, reusable adhesive materials such as magic tape or special tape are used to connect the middle plate 100 and the inner liner box 200. This method is simple, but the adhesive material may need to be replaced regularly. In detail, the back surface of the middle plate 100 and the connecting end 240 of the inner liner box 200 are respectively pasted with magic tape or special tape. The middle plate 100 is aligned with the inner liner box 200, and the two are bonded by gently pressing. When disassembled, the two can be separated by gently tearing.

[0057] Furthermore, it should be noted that the cleaning and maintenance are facilitated, which helps to maintain the hygiene and performance of the equipment.

[0058] In some embodiments, the connecting end 240 and the middle plate 100 are connected by clamping, and the end surface and the back surface of the connecting end 240 are arranged in parallel, and the end surface and the back surface of the connecting end 240 abut.

[0059] In these embodiments, the connecting end 240 of the inner liner box 200 and the middle plate 100 are connected by clamping, and the end surface of the connecting end 240 and the back surface of the middle plate 100 are arranged in parallel and abut each other, thereby realizing the sealing of the connection between the two on the basis of ensuring that the two can be disassembled.

[0060] For example, the back of the middle plate 100 is provided with several clips or slots 110. The connecting end 240 of the inner liner box 200 is provided with corresponding slots 110 or clips, which match the clips or slots 110 on the middle plate 100. The end face of the connecting end 240 is kept parallel to the back of the middle plate 100 to ensure that the contact surfaces of the two are completely in contact. That is, after the clips are engaged, the end face of the connecting end 240 is tightly abutted against the back of the middle plate 100, forming a sealed interface to prevent external contaminants from entering the interior of the inner liner box 200.

[0061] Optionally, a sealing gasket is provided on the end face of the connecting end 240 to further enhance the sealing effect and reduce the machining accuracy of the connecting end 240 and / or the back side.

[0062] like Figure 1 , Figure 2 and Figure 3 As shown, in some embodiments, the connecting end 240 has at least two latches 220, the middle plate 100 has at least two slots 110, the at least two latches 220 are spaced apart along the circumferential direction of the opening of the inner liner box 200, the at least two slots 110 and the at least two latches 220 are arranged in a one-to-one correspondence, and the latches 220 and the corresponding slots 110 are engaged.

[0063] In these embodiments, this design not only provides a reliable connection, but also simplifies the assembly process and enhances the stability and sealing of the connection.

[0064] The connecting end 240 of the inner liner box 200 is provided with at least two latches 220, which are spaced apart circumferentially along the opening of the inner liner box 200. The back of the middle plate 100 is provided with at least two slots 110, which correspond one-to-one with the latches 220 of the inner liner box 200. Each latch 220 engages with its corresponding slot 110 to ensure a firm and reliable connection between the middle plate 100 and the inner liner box 200. The latches 220 and slots 110 are distributed circumferentially along the opening of the inner liner box 200, making the connection more uniform and stable.

[0065] The specific assembly process is as follows: Align the middle plate 100 with the connecting end 240 of the inner liner box 200, ensuring that the latch 220 and the slot 110 are aligned. Gently press down on the middle plate 100 to allow the latch 220 to enter the slot 110 and engage. Ensure that all latches 220 are correctly engaged in their corresponding slots 110, and that the end face of the connecting end 240 is fully flush with the back of the middle plate 100.

[0066] For example, in this embodiment, there are two latches 220, which are arranged opposite each other. Of course, in other embodiments, the number of latches 220 may be three, four, five, six, etc.

[0067] Correspondingly, the number of the card slots 110 and the number of the card tongues 220 are consistent, which will not be described here.

[0068] As shown in the drawings, in some embodiments, the card tongue 220 is arranged in the corresponding card slot 110, so that the inner wall of the card slot 110 and the outer wall of the card tongue 220 form a clamping force. Figure 1

[0069] In some embodiments, the card tongue 220 is arranged in the corresponding card slot 110, so that the inner wall of the card slot 110 and the outer wall of the card tongue 220 form a clamping force. That is, the size of the card tongue 220 and the card slot 110 is designed so that when the card tongue 220 is arranged in the card slot 110, the inner wall of the card slot 110 can tightly wrap the outer wall of the card tongue 220, generating a certain friction force. When disassembling, the middle plate 100 is pressed and rotated slightly to overcome the clamping force and make the card tongue 220 separate from the card slot 110.

[0070] Obviously, this arrangement can maximize the pushing of the middle plate 100 to extrude the connecting end 240, further improving the sealing effect between the end face and the back face of the connecting end 240.

[0071] In some embodiments, at least the part of the inner liner box 200 that contacts the back face is designed as a flexible or elastic part, so that the end face of the connecting end 240 can deform to fit the back face.

[0072] In these embodiments, at least the part of the inner liner box 200 that contacts the back face of the middle plate 100 is designed as a flexible or elastic part, so that the end face of the connecting end 240 can deform to fit the back face of the middle plate 100. This design not only improves the stability and sealing of the connection, but also increases the adaptability and reliability of the connection.

[0073] The part of the inner liner box 200 that contacts the back face of the middle plate 100 is made of a flexible or elastic material. That is, the end face of the connecting end 240 is designed as a flexible or elastic part, which can deform when subjected to pressure and better fit the back face of the middle plate 100.

[0074] Obviously, the deformation of the flexible or elastic part makes the end face of the connecting end 240 form a tight contact with the back face of the middle plate 100, effectively preventing external contaminants from entering the inner liner box 200, and improving the sealing effect. Moreover, the flexible or elastic part can adapt to the slight unevenness of the back face of the middle plate 100, ensuring that a good seal can be formed even if the surface is not completely flat. Furthermore, flexible or elastic materials generally have good durability and can maintain performance during multiple assembly and disassembly processes, extending the service life.

[0075] ​Exemplarily, the end face of the connecting end 240 is provided with an elastic sealing gasket. Of course, in other embodiments, the inner liner box 200 is provided as a whole in an elastic structure, so that the end face of the connecting end 240 can be deformed after contacting the back face. For example, the inner liner box 200 is made of a blister material such as APET, PETG or the like by blistering, which has a lower overall processing cost and a simpler process compared with traditional injection molding.

[0076] As shown in Figure 3 , in some embodiments, the connecting end 240 has a flange 210, and the end face of the flange 210 abuts against the back face.

[0077] In some embodiments, such a design not only provides more reliable connection, but also enhances the stability and sealing of the connection. The connecting end 240 of the inner liner box 200 is provided with a flange 210, which extends outward along the edge of the opening of the inner liner box 200, thereby increasing the contact area between the connecting end 240 and the back face and improving the sealing effect.

[0078] As shown in Figure 3 , in some embodiments, the inner liner box 200 has a height direction X, and the side wall of the inner liner box 200 is distributed with a plurality of reinforcing ribs 230, which are arranged along the height direction X, and the connecting end 240 is located at the top of the inner liner box 200, and the reinforcing ribs 230 are formed by inwardly recessing the side wall of the inner liner box 200.

[0079] In these embodiments, such a design not only enhances the structural strength of the inner liner box 200, but also improves its stability and durability. The inner liner box 200 has a clear height direction X, i.e. the direction from the bottom to the top, and the connecting end 240 is located at the top, and the reinforcing ribs 230 are uniformly distributed around the inner liner box 200.

[0080] Among them, the reinforcing ribs 230 are formed by inwardly recessing the side wall of the inner liner box 200, i.e. the reinforcing ribs 230 form a series of inwardly recessed lines on the side wall, which increases the longitudinal rigidity of the inner liner box 200 and makes it less likely to deform when subjected to external pressure. The design of the inwardly recessed reinforcing ribs 230 not only increases the thickness of the side wall, but also disperses the external pressure, improves the overall structural strength of the inner liner box 200, and does not increase the external size.

[0081] As shown in Figure 4 , Figure 5 , and Figure 6As shown, in some embodiments, the present application also provides a packaging box 300 for the mid-plate assembly as described in any of the above embodiments, the packaging box 300 comprising an outer liner box 320 having an outer liner box 320 opening formed to allow the mid-plate assembly to pass in and out of the outer liner box 320, and a cover plate 310 removably disposed at the outer liner box 320 opening to close the outer liner box 320 opening.

[0082] In these embodiments, the present application also provides a packaging box 300 specially designed for accommodating and protecting the mid-plate assembly as described in the above embodiments.

[0083] The top of the outer liner box 320 is provided with an opening, which forms an access passage to allow the mid-plate assembly to conveniently pass in and out of the outer liner box 320. The internal space of the outer liner box 320 is designed to fit the size of the mid-plate assembly, ensuring that the mid-plate assembly will not shake or be damaged during transportation and storage.

[0084] The cover plate 310 is removably disposed at the outer liner box 320 opening and can be easily opened and closed. The cover plate 310 tightly fits the edge of the outer liner box 320 opening, forming a sealed environment to prevent external contaminants from entering the interior of the outer liner box 320.

[0085] The specific use process is as follows: place the mid-plate assembly into the outer liner box 320 to ensure that the mid-plate assembly is placed stably. Align the cover plate 310 with the outer liner box 320 opening to ensure that the cover plate 310 tightly fits the edge of the outer liner box 320 opening. Close the cover plate 310 to ensure that the cover plate 310 completely closes the outer liner box 320 opening, facilitating subsequent sterilization use.

[0086] Open the cover plate 310 and remove it from the outer liner box 320 opening. Remove the mid-plate assembly from the outer liner box 320. That is, place the entire box of pipette tips on the carrier. Through the matching of the positioning portion 130 on the mid-plate 100 and the carrier, the tips can be accurately positioned on the carrier, thereby achieving accurate positioning of the tip placement position. Obviously, due to the protection of the inner liner box 200, the head end of the tip is completely wrapped outside, thereby achieving protection against external contamination during pipetting.

[0087] For example, the cover plate 310 and the outer liner box 320 are buckled. Alternatively, the cover plate 310 is a sealing film, which covers the outer liner box 320 opening. When in use, the sealing film can be torn open.

[0088] In some embodiments, the present application also provides an automated pipetting device comprising the mid-plate assembly as described in any of the above embodiments.

[0089] Since the above-mentioned middle plate assembly has the above-mentioned technical effects, the automated pipetting device comprising the middle plate assembly should also have the same technical effects, which will not be described here again.

[0090] Exemplarily, the automated pipetting device further comprises a pipetting mechanical arm, a carrier, and the middle plate assembly, the middle plate assembly is positioned and assembled on the carrier, and the pipetting mechanical arm can access the pipette tip on the middle plate assembly.

[0091] As shown in Figure 7 , Figure 8 and Figure 9 , in some embodiments, the present application also provides a pipette tip adapted to the middle plate assembly in any of the above-mentioned embodiments, the pipette tip comprising a pipette body 400, the pipette body 400 is inserted into the tip socket 120, the pipette body 400 has a connection port end 410 and a liquid suction port end 420, the inner wall of the connection port end 410 has at least two sealing rings 411, the at least two sealing rings 411 are arranged at intervals in the axial direction of the pipette body 400, and in any two adjacent sealing rings 411, the inner diameter of the sealing ring 411 close to the liquid suction port end 420 is smaller than the inner diameter of the sealing ring 411 away from the liquid suction port end 420.

[0092] In these embodiments, a specially designed pipette tip is adapted to a specific plate assembly. The pipette body 400 is the main part of the pipette tip, which is used to suck and transfer liquid. The pipette body 400 will pass through the tip socket 120 on the plate assembly. The connection port end 410 is the end connected to the intervention head of the pipette. The liquid suction port end 420 is the end that enters the liquid to suck the sample.

[0093] At least two sealing rings 411 are arranged on the inner wall of the connection port end 410, which are arranged at intervals in the axial direction of the pipette body 400. The purpose of this design is to ensure better sealing to prevent liquid leakage or external contamination. The inner diameter of the sealing ring 411 close to the liquid suction port end 420 is smaller, while the inner diameter of the sealing ring 411 away from the liquid suction port end 420 (i.e. closer to the connection port end 410) is larger, which helps to provide a stepped sealing effect between the intervention head of the pipette and the connection port end, further enhancing the sealing performance. The design of this pipette tip can improve its reliability in high-precision experiments, especially in situations where strict control of contamination and cross-contamination is required. By using sealing rings 411 of different diameters, certain assembly tolerances can be allowed while maintaining a tight fit, thereby simplifying the manufacturing process and reducing costs. In addition, good sealing performance is crucial for maintaining accurate volume measurement, especially when handling small amounts of liquid.

[0094] Exemplarily, in this embodiment, the number of sealing rings 411 is 4. Of course, in other embodiments, the number of sealing rings 411 can also be 3, 5, 6, 7, 8, or 9, etc.

[0095] Optionally, the sealing ring 411 is provided with elasticity. For example, the material of the sealing ring 411 can be plastic, rubber, etc.

[0096] Of course, in some embodiments, the middle part of the pipette body 400 is provided with a filter element 430, which further filters and prevents pollution.

[0097] For example, the caliber of the liquid suction end 420 is 1.6 mm, and the total length of the pipette body 400 is 140 mm. When used on an automated device, the multiple sealing rings 411 are tightly combined with the intervention head on the pipette, which can effectively ensure good sealing, and more than 3000 ml of liquid can be sucked without liquid flowing out or liquid droplets forming for more than 30 seconds. In addition, compared with the conventional 0.7 mm caliber of the pipette suction head, the success rate of sucking abnormal liquefied semen is increased by more than 50%.

[0098] It should be noted that the above-mentioned middle plate assembly, packaging box and pipette suction head are matched to form an integral product for sale, which can be directly used without separately transferring the middle plate assembly and / or pipette suction head, and the anti-pollution property can be further improved.

[0099] In all examples shown and described herein, any specific values should be interpreted as merely exemplary and not as a limitation, and thus, other examples of the example embodiments can have different values.

[0100] It should be noted that similar reference numbers and letters represent similar items in the following drawings, and thus, once an item is defined in one drawing, it does not need to be further defined and explained in subsequent drawings.

[0101] The above-described embodiments only express several implementation manners of the present application, and the description is relatively specific and detailed, but it should not be understood as a limitation on the scope of the present application. It should be noted that for those skilled in the art, without departing from the concept of the present application, a number of modifications and improvements can be made, which are all within the protection scope of the present application.

Claims

1. A midplate assembly comprising a midplate having a plurality of suction head receptacles and a positioning portion, characterized by, The middle plate assembly further comprises: The inner liner box has a connecting end with an inner liner box opening, the back surface of the middle plate and the connecting end of the inner liner box are connected to close the inner liner box opening, and the plurality of tip insertion holes are located at one end of the back surface within the coverage of the inner liner box opening; wherein the positioning portion is located outside the inner liner box, so that the middle plate can be positioned with the carrier.

2. The mid-panel assembly of claim 1, wherein, The back surface of the middle plate and the connecting end of the inner liner box are detachably connected.

3. The mid-panel assembly of claim 2, wherein, The connecting end and the middle plate are clamped, and the end surface of the connecting end and the back surface are arranged in parallel, and the end surface of the connecting end and the back surface are in abutment.

4. The mid-panel assembly of claim 3, wherein, The connecting end has at least two clamping tongues, and the middle plate has at least two clamping grooves, the at least two clamping tongues are arranged at intervals along the circumference of the inner liner box opening, the at least two clamping grooves and the at least two clamping tongues are arranged one-to-one, and the clamping tongue and the corresponding clamping groove are clamped and matched.

5. The mid-panel assembly of claim 4, wherein, The clamping tongue is arranged in the corresponding clamping groove, so that a clamping force is formed between the inner wall of the clamping groove and the outer wall of the clamping tongue.

6. The mid-panel assembly of claim 4, wherein, The part of the inner liner box in contact with the back surface is arranged as a flexible part or an elastic part, so that the end surface of the connecting end can be deformed to fit the back surface.

7. The mid-panel assembly of claim 6, wherein, The connecting end has a turned edge, and the end surface of the turned edge and the back surface are in abutment.

8. The mid-panel assembly of claim 1, wherein, The inner liner box has a height direction, the side wall of the inner liner box is distributed with a plurality of reinforcing ribs, the reinforcing ribs are arranged in the height direction, the connecting end is located at the top of the inner liner box, and the reinforcing ribs are formed by the side wall of the inner liner box being inwardly recessed.

9. A packaging box, characterized in that The packaging box applied to the middle plate assembly of any one of claims 1 to 8 comprises: An outer liner box and a cover plate, the outer liner box has an outer liner box opening, the outer liner box opening is formed to form an access passage for the middle plate assembly to access the outer liner box, and the cover plate is detachably arranged at the outer liner box opening to close the outer liner box opening.

10. An automated pipetting device characterized in that, The automated pipetting device comprises the middle plate assembly of any one of claims 1 to 8.

11. A pipette tip adapted to the mid-plate assembly of any one of claims 1 to 8, characterized in that, The pipetting tip comprises a pipette body, the pipette body is arranged in the tip insertion hole, the pipette body has a connecting port end and a liquid suction port end, the inner wall of the connecting port end has at least two sealing rings, the at least two sealing rings are arranged at intervals in the axial direction of the pipette body, and in any two adjacent sealing rings, the inner diameter of the sealing ring close to the liquid suction port end is smaller than the inner diameter of the sealing ring away from the liquid suction port end.

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