Atomization administration device for test mice

Abstract

The utility model discloses a test mouse atomization dosing device which comprises a controller and an atomizer, a rectangular dosing box is fixedly installed on the upper side of the controller, the atomizer is provided with a spray head, a box cover is connected to the upper end of the dosing box in a clamped mode, two parallel partition plates are arranged in the dosing box, and mouse grooves are formed between the partition plates and the left side wall and the right side wall of the dosing box respectively. A Y-shaped flow guide plate is arranged in the middle of an inner cavity of the medicine feeding box, air flow channels with the same width are formed between the left side and the right side of the flow guide plate and the partition plates, the two air flow channels converge at the rear end of the flow guide plate, a rotatable flow distribution plate is installed at the rear end of the flow guide plate, and a connecting plate is fixedly connected between the upper sides of the rear ends of the two partition plates. And an arc surface is arranged on the front side of the connecting plate and is in contact with the movable end of the splitter plate. Different amounts of medicine can be dispensed to two groups of mice at the same time, use in a contrast test is facilitated, atomized medicine can cover the whole mouse groove, and it is guaranteed that the mice in each group absorb the medicine evenly.

Description

Technical Field

[0001] This utility model relates to the field of experimental instrument technology, specifically to an atomized drug delivery device for experimental mice. Background Technology

[0002] Nebulized drug delivery to mice is a method of drug administration that delivers drugs into the respiratory tract of mice in a nebulized form. It typically involves using a nebulizer to convert the drug into tiny particles, suspending them in the air, which the mice then inhale. The advantage of this method is that it acts directly on the mouse's respiratory system, making the drug easier to absorb and deliver to target tissues or organs. It has wide applications in research on respiratory diseases, inhaled drug therapy, and drug metabolism. However, existing mouse nebulizers, for experiments requiring two groups to be compared based on concentration or dosage, require two separate administration sessions or two separate devices for each group of mice, leading to excessively long administration times or high equipment costs. Utility Model Content

[0003] The purpose of this invention is to provide an atomized drug delivery device for experimental mice to solve the problems mentioned in the background art.

[0004] To achieve the above objectives, this utility model provides the following technical solution: a nebulized drug delivery device for experimental mice, comprising a controller and a nebulizer. A rectangular drug delivery box is fixedly installed on the upper side of the controller. The nebulizer is equipped with a nozzle. A lid is snapped onto the upper end of the drug delivery box. Both the drug delivery box and the lid are made of transparent plastic. Two parallel partitions are arranged inside the drug delivery box, forming mouse grooves between the partitions and the left and right side walls of the drug delivery box. A Y-shaped guide plate is arranged in the middle of the inner cavity of the drug delivery box. Airflow channels of equal width are formed between the left and right sides of the guide plate and the partitions. The two airflow channels are located at the guide plate. The two partitions converge at their rear ends. A rotatable diverter plate is installed at the rear end of the guide plate. A connecting plate is fixedly connected between the upper rear ends of the two partitions. The front side of the connecting plate has an arc surface that contacts the movable end of the diverter plate. The front side of the partition has a ventilation hole that connects the airflow channel to the mouse groove. A rectangular mounting box is fixedly connected to the rear end of the drug delivery box. The rear side of the drug delivery box has three through holes, which are located between the two partitions and at the rear ends of the two mouse grooves, respectively. A fan is installed in the mounting box. The fan blows air through the middle through hole to the area between the two partitions. The nozzle is located in front of the fan.

[0005] Preferably, the lower part of the inner cavity of the drug delivery box is provided with a horizontal support plate, the bottom of the partition and the guide plate are in contact with the support plate, a slot is formed between the bottom of the support plate and the inner cavity of the drug delivery box, the front end of the slot is provided with a rectangular insertion port and a feces box is inserted into it through the insertion port, and a round hole is opened in the support plate area at the bottom of the mouse trough, the round hole connecting the mouse trough and the feces box.

[0006] Preferably, the connecting plate has multiple evenly arranged slots on its arc surface, which are used to engage and position the free end of the diverter plate.

[0007] Preferably, the lower side of the lid is provided with a flange, which engages with the upper port of the medication box.

[0008] Compared with the prior art, the advantages of this invention are: it can simultaneously administer different amounts of drug to two groups of mice, making it convenient for use in comparative experiments. Because the airflow circulates at both ends of the mouse trough, the atomized drug can cover the entire trough, ensuring uniform absorption by the mice in each group. Attached Figure Description

[0009] Figure 1 This is a schematic diagram of the main structure of this utility model;

[0010] Figure 2 This is a three-dimensional structural diagram of the medicine box;

[0011] Figure 3 This is a top view of the medication box.

[0012] In the diagram: 1. Controller; 2. Dosage box; 3. Feces box; 4. Box cover; 5. Mounting box; 6. Partition; 7. Ventilation hole; 8. Mouse trough; 9. Guide plate; 10. Diverter plate; 11. Connecting plate; 12. Fan; 13. Nozzle. Detailed Implementation

[0013] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0014] Please see Figure 1-3 This utility model provides a technical solution: a nebulized drug delivery device for experimental mice, including a controller 1 and a nebulizer. Both the controller 1 and the nebulizer are existing technologies and will not be described in detail. The controller 1 is used to control the opening and closing of the nebulizer and its size adjustment. A rectangular drug delivery box 2 is fixedly installed on the upper side of the controller 1. The nebulizer is equipped with a nozzle 13. A lid 4 is snapped onto the upper end of the drug delivery box 2. A flange is provided on the lower side of the lid 4, which snaps onto the upper port of the drug delivery box 2 to achieve a good sealing effect. Both the drug delivery box 2 and the lid 4 are made of transparent plastic. Two parallel partitions 6 are provided inside the drug delivery box 2. The partitions 6 form mouse grooves 8 between themselves and the left and right side walls of the drug delivery box 2. A Y-shaped guide plate 9 is provided in the middle of the inner cavity of the drug delivery box 2. Airflow channels of equal width are formed between the left and right sides of the guide plate 9 and the partitions 6. These airflow channels are used to flow the nebulized drug.

[0015] Two airflow channels converge at the rear end of the guide plate 9. A rotatable diverter plate 10 is installed at the rear end of the guide plate 9. A connecting plate 11 is fixedly connected between the upper rear ends of the two partition plates 6. The front side of the connecting plate 11 has an arc surface that contacts the movable end of the diverter plate 10. The arc surface of the connecting plate 11 has multiple evenly arranged slots for locking the free end of the diverter plate 10 for positioning. The diverter plate 10 is made of plastic and has a certain elastic deformation allowance. When the diverter plate 10 and the guide plate 9 are collinear, the ratio of the cross-sectional areas of the rear inlets of the two airflow channels is 1:1, so the amount of drug flowing into the two airflow channels is equal.

[0016] The diverter plate 10 deflects to the left or backward at a certain angle, causing a change in the cross-sectional area of ​​the inlet, which in turn adjusts the amount of drug entering the two airflow channels. A ventilation hole 7 is provided on the front side of the partition plate 6, connecting the airflow channel to the mouse trough 8. The ventilation hole 7 is used to connect the atomized drug in the airflow channel to the mouse trough 8. A rectangular mounting box 5 is fixedly connected to the rear end of the drug delivery box 2. Three through holes are provided on the rear side of the drug delivery box 2, located between the two partition plates 6 and at the rear ends of the two mouse troughs 8. To prevent mice from crawling into the mounting box 5, an isolation net is installed in the through hole at the rear end of the mouse trough 8. A fan 12 is installed in the mounting box 5, blowing air through the middle through hole to the area between the two partition plates 6. The nozzle 13 is located in front of the fan 12.

[0017] The lower part of the inner cavity of the administration box 2 is provided with a horizontal tray. The bottom of the partition 6 and the guide plate 9 are in contact with the tray. A slot is formed between the bottom of the tray and the inner cavity of the administration box 2. The front end of the slot is provided with a rectangular insertion port, and the feces box 3 is inserted into the slot. A round hole is opened in the tray area at the bottom of the mouse trough 8. The round hole connects the mouse trough 8 and the feces box 3. During the experiment, the mouse's feces will leak into the feces box 3 below for collection, which is convenient for emptying and cleaning.

[0018] Working principle: During the comparative test, the two groups of mice are placed in two mouse troughs 8 respectively. Rotating the flow divider 10 can adjust the distribution ratio of the nebulized drug between the two airflow channels (i.e., adjust the distribution ratio of the drug flowing to the two mouse troughs 8). The nebulized drug enters from the front side of the mouse trough 8 and then flows backward to form a cycle. The airflow covers the entire mouse trough 8 from front to back, ensuring that each mouse can absorb the drug.

[0019] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A nebulized drug delivery device for experimental mice, comprising a controller (1) and a nebulizer, wherein a rectangular drug delivery box (2) is fixedly mounted on the upper side of the controller (1), the nebulizer is provided with a nozzle (13), and a box cover (4) is snapped onto the upper end of the drug delivery box (2), both the drug delivery box (2) and the box cover (4) are made of transparent plastic material, characterized in that: The administration box (2) has two parallel partitions (6) inside. The partitions (6) form grooves (8) between the left and right side walls of the administration box (2). A Y-shaped guide plate (9) is provided in the middle of the inner cavity of the administration box (2). The left and right sides of the guide plate (9) form airflow channels of equal width between the partitions (6). The two airflow channels converge at the rear end of the guide plate (9). A rotatable diverter plate (10) is installed at the rear end of the guide plate (9). A connecting plate (11) is fixedly connected between the upper rear ends of the two partitions (6). The front side is provided with an arc surface that contacts the movable end of the diverter plate (10). The front side of the partition plate (6) is provided with a ventilation hole (7) that connects the airflow channel to the rat groove (8). The rear end of the drug delivery box (2) is fixedly connected to a rectangular mounting box (5). The rear side of the drug delivery box (2) is provided with three through holes, which are located between the two partition plates (6) and at the rear ends of the two rat grooves (8), respectively. The mounting box (5) is equipped with a fan (12). The fan (12) blows air through the middle through hole to the area between the two partition plates (6). The nozzle (13) is located in front of the fan (12).

2. The nebulized drug delivery device for experimental mice according to claim 1, characterized in that: The lower part of the inner cavity of the drug delivery box (2) is provided with a horizontal tray. The bottom of the partition (6) and the guide plate (9) are in contact with the tray. A slot is formed between the bottom of the tray and the inner cavity of the drug delivery box (2). The front end of the slot is provided with a rectangular insertion port and a feces box (3) is inserted into it through the insertion port. A round hole is opened in the tray area at the bottom of the rat trough (8). The round hole connects the rat trough (8) and the feces box (3).

3. The nebulized drug delivery device for experimental mice according to claim 1, characterized in that: The connecting plate (11) has a plurality of evenly arranged slots on its arc surface, which are used to engage the free end of the diverter plate (10) for positioning.

4. The nebulized drug delivery device for experimental mice according to claim 1, characterized in that: The lower side of the lid (4) is provided with a flange, which engages with the upper port of the medication box (2).

Images