Inlet guard column device of chromatographic column

Abstract

The utility model discloses an inlet guard column device of a chromatographic column, which relates to the technical field of mounting equipment and comprises a chromatographic column main body and a connector arranged on one side of the chromatographic column main body. Through the arrangement of the pressing mechanism arranged on one side of the sliding pipe, the sliding pipe is held and pulled outwards, the sliding pipe drives the spring to move and deform, the pipeline connector is inserted into the sleeve, and the positioning ball is extruded by the pipeline connector and contracts outwards along the annular groove; when the pipeline connector is inserted into the bottom of the sleeve, the positioning ball moves to the fixing groove of the pipeline connector, the sliding pipe is loosened, the sliding pipe returns to the original position under the action of elastic deformation of the spring, the positioning ball is squeezed by the sliding pipe to retract inwards along the annular groove, and the positioning ball is buckled into the fixing groove of the pipeline connector. At the moment, the sleeve and the pipeline connector are connected together in a buckling mode, the buckling connection mode achieves the effect of facilitating disassembly, and the user experience is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to detection equipment technical field, concretely is a kind of import protection column device of chromatographic column. BACKGROUND

[0002] Chromatographic column is composed of column tube, pressure cap, sleeve, sieve plate, joint, screw etc., and bears the separation function in chromatographic system.In the process of high-efficiency liquid phase analysis detection sample liquid, chromatographic column will be contaminated from sample liquid and chromatographic system, thereby leading to poor durability of chromatographic column, shortened life, and using protection column can greatly reduce the degree of pollution of analysis column, prolong the service life of analysis column.The protection column is located between sample injector and analysis column, and the main effects are two aspects: intercepting insoluble particles and adsorbing impurities in sample liquid matrix, and the protection column often needs to be replaced after a period of use to ensure the maximum play of the effect, but when replacing, the protection column is often detached by rotating sample injector or analysis column, which is more cumbersome to operate, therefore, a protection column structure of chromatographic analysis instrument chromatographic column is proposed, which only needs to operate the protection column structure when disassembling, which is more convenient and greatly improves the user experience.

[0003] The utility model discloses a kind of protection column structure of chromatographic analysis instrument chromatographic column, and the utility model uses the clamping between installation strip and clamping groove, cooperate the elasticity of spring, so that clamping block is clamped in the clamping groove of the opposite side of first limit ring and second limit ring, finally through the thread connection between bolt and mounting screw hole, installation strip is fixed, when disassembling, bolt is disassembled and adjust first limit ring and second limit ring, so it is convenient to adjust protection column main body, so that the thread seat at one end and sample injector or analysis column are separated, sample injector or analysis column is directly taken down, finally another place thread seat is rotated out, realize the disassembly of protection column main body, installation is also similar, so it avoids the rotation operation to larger sample injector or analysis column, so that disassembly is more convenient, provide a new idea for the installation and disassembly of protection column main body, improve the service life of device and user experience.

[0004] But the protection column structure of existing chromatographic column is single in function, only can realize disassembly convenience, cannot replace column core, needs to be removed as a whole, cost is higher, not conducive to the rational use of resources, therefore a kind of import protection column device of chromatographic column is presented. UTILITY MODEL CONTENTS

[0005] The utility model provides a kind of import protection column device of chromatographic column to solve the problem that the protection column structure of existing chromatographic column realizes disassembly convenience while cannot replace column core.

[0006] The utility model provides the following technical scheme: an inlet protection column device of chromatographic column, including chromatographic column main part and the connecting port of setting in chromatographic column main part one side, still include: the thread groove of setting in the inside of connecting port, the inside screw thread connection of thread groove has the joint, the side fixed connection of joint has the sleeve, the inside of sleeve is provided with sealing ring, the surface of sleeve is sleeved with the sliding tube, the side fixed connection of sliding tube has the pressing mechanism, the pressing mechanism includes spring and positioning ball; The water stop mechanism of setting in the inside of sleeve, the water stop mechanism includes water stop joint, liquid inlet and water stop rod; The pipeline joint of setting in the inside of sleeve, the surface of pipeline joint is provided with fixed groove, the side fixed connection of pipeline joint has protection column main part, the surface fixed connection of protection column main part has monitoring mechanism, the monitoring mechanism includes pressure gauge, battery, pressure sensor, alarm indicator and controller.

[0007] As a preferred technical scheme of the utility model, the spring is fixedly connected to one side of the sliding tube, six groups of positioning balls are arranged on the surface of the sleeve, annular grooves are arranged on the surface of the positioning balls, and the positioning balls are clamped to the side surface of the sleeve.

[0008] As a preferred technical scheme of the utility model, the water stop joint is inserted into the inside of the sleeve, two groups of liquid inlets are arranged on the surface of the water stop joint, and the water stop rod is fixedly connected to the inside of the water stop joint.

[0009] As a preferred technical scheme of the utility model, the pressure gauge is fixedly connected to the surface of the protection column main part, the battery is electrically connected to one side of the pressure gauge through a power line, the pressure sensor is electrically connected to one side of the battery through a power line, the alarm indicator is electrically connected to one side of the pressure sensor through a power line, and the controller is electrically connected to one side of the alarm indicator through a power line.

[0010] As a preferred technical scheme of the utility model, the spring is located on the surface of the sleeve, and one end of the spring is fixedly connected to one side of the sleeve.

[0011] As a preferred technical scheme of the utility model, the joint is screw-connected to the inside of the thread groove, and the inside of the chromatographic column main part is provided with a filler.

[0012] As a preferred technical scheme of the utility model, the column core is inserted into the inside of the protection column main part, and the column core is matched with the size of the protection column main part.

[0013] As a preferred technical scheme of the utility model, the thread hole is arranged on one side of the protection column main part, and the inside of the thread hole is screw-connected to the external liquid inlet.

[0014] Compared with the prior art, the utility model provides a kind of inlet guard column device of chromatographic column, with following beneficial effects:

[0015] 1, the inlet guard column device of chromatographic column, by the setting of the press mechanism of setting in the sliding tube one side, hold the sliding tube and pull out, sliding tube drives spring movement and occurs deformation, pipe joint is inserted into the sleeve inside, and positioning ball is extruded along the annular groove and shrinks outward when pipe joint inserts the bottom of sleeve, positioning ball moves to the fixed groove of pipe joint, loosen sliding tube, under the action of spring elastic deformation, sliding tube returns to original position, and positioning ball is extruded along the annular groove and shrinks inward by sliding tube, and positioning ball buckle is into the fixed groove of pipe joint, at this time, sleeve and pipe joint buckle connection are connected together, and the effect of convenient disassembly is played by buckle connection mode, improve user experience.

[0016] 2, the inlet guard column device of chromatographic column, by the setting of the water stop mechanism of setting in the sleeve inside, when connecting port is connected with joint screw thread, water stop rod is opposite with chromatographic column internal filler, water stop rod moves to protection column and pushes water stop joint away from sleeve export, and inlet appears sample liquid can flow, when connecting port and joint connection place fall off, water stop joint moves to sleeve export under the action of sample liquid flow, and inlet is blocked sample liquid cannot flow out, prevent falling off effect,

[0017] 3, the inlet guard column device of chromatographic column, by the setting of the detection mechanism of setting in the surface of protection column main part, the column core in protection column main part is usually equipped with filler, can intercept small precipitate, particle or chemical substance, pressure sensor is used for monitoring the pressure when sample liquid flows in protection column main part, when the precipitate in column core is too much, pressure value rises, controller controls alarm indicator light alarm and prompts staff to clean or replace in time, to prevent its influence filtration effect, so as to affect the stability and reproducibility of sample liquid entering chromatographic column and affecting chromatographic analysis. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 It is whole structure schematic diagram of the utility model;

[0019] Figure 2 It is press mechanism structure schematic diagram of the utility model;

[0020] Figure 3 It is water stop mechanism cross section structure schematic diagram of the utility model;

[0021] Figure 4 It is monitoring mechanism structure schematic diagram of the utility model.

[0022] In the figure: 1, the main body of the chromatographic column; 2, the connecting port; 3, the threaded groove; 4, the connector; 5, the sleeve; 6, the sealing ring; 7, the sliding tube; 8, the pressing mechanism; 801, the spring; 802, the positioning ball; 9, the water stop mechanism; 901, the water stop connector; 902, the liquid inlet; 903, the water stop rod; 10, the pipeline connector; 11, the protection column main body; 12, the monitoring mechanism; 1201, the pressure gauge; 1202, the battery; 1203, the pressure sensor; 1204, the alarm indicator light; 1205, the controller; 13, the column core. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0024] Please refer to Figures 1-4 The utility model discloses a kind of inlet protection column devices of chromatographic column, including chromatographic column main body 1 and the connecting port 2 of setting in chromatographic column main body 1 side, still include: threaded groove 3 is set in connecting port 2 inside, threaded groove 3 is connected with connector 4 in inside thread, the side fixedly connected with sleeve 5 of connector 4, the inside of sleeve 5 is provided with sealing ring 6, the surface of sleeve 5 is sleeved with sliding tube 7, the side fixedly connected with pressing mechanism 8 of sliding tube 7, and pressing mechanism 8 includes spring 801 and positioning ball 802;Water stop mechanism 9 is set in the inside of sleeve 5, and water stop mechanism 9 includes water stop connector 901, liquid inlet 902 and water stop rod 903;Pipeline connector 10 is set in the inside of sleeve 5, and the surface of pipeline connector 10 is provided with fixed recess, the side fixedly connected with protection column main body 11 of pipeline connector 10, the surface of protection column main body 11 is fixedly connected with monitoring mechanism 12, and monitoring mechanism 12 includes pressure gauge 1201, battery 1202, pressure sensor 1203, alarm indicator light 1204 and controller 1205.

[0025] Specifically, spring 801 is fixedly connected to the side of sliding tube 7, the surface of sleeve 5 is provided with six sets of positioning ball 802, the surface of positioning ball 802 is provided with annular groove, and positioning ball 802 is clamped to the side surface of sleeve 5.

[0026] In the embodiment, sliding tube 7 is slid outward, sliding tube 7 drives spring 801 to stretch outward, pipeline connector 10 is inserted into the inside of sleeve 5, positioning ball 802 is extruded to shrink outward and then rebound to fix in the fixed recess of pipeline connector 10, sliding tube 7 is loosened, and sliding tube 7 is driven to stretch back to the original position under the action of elastic deformation of spring 801.

[0027] Specifically, the water stop joint 901 is inserted into the inside of the sleeve 5, and the surface of the water stop joint 901 is provided with two groups of liquid inlet ports 902, and the inside of the water stop joint 901 is fixedly connected with a water stop rod 903.

[0028] In the embodiment, the water stop rod 903 moves towards the protection column to push the water stop joint 901 away from the outlet of the sleeve 5, and the liquid inlet port 902 is exposed to the liquid flow. When the connection between the connection port 2 and the joint 4 is disconnected, the water stop joint 901 moves towards the outlet of the sleeve 5 under the action of the liquid flow, and the liquid inlet port 902 is blocked and the liquid cannot flow out, thereby preventing disconnection.

[0029] Specifically, the pressure gauge 1201 is fixedly connected to the surface of the protection column body 11, one side of the pressure gauge 1201 is electrically connected with a battery 1202 through a power line, one side of the battery 1202 is electrically connected with a pressure sensor 1203 through a power line, one side of the pressure sensor 1203 is electrically connected with an alarm indicator lamp 1204 through a power line, and one side of the alarm indicator lamp 1204 is electrically connected with a controller 1205 through a power line.

[0030] In the embodiment, the pressure sensor 1203 detects the flow pressure of the liquid in the protection column, and when the value is too high, the controller 1205 triggers the alarm indicator lamp 1204 to light up, indicating that there is too much sediment inside and it needs to be cleaned or replaced.

[0031] Specifically, the spring 801 is located on the surface of the sleeve 5, and one end of the spring 801 is fixedly connected to one side of the sleeve 5.

[0032] In the embodiment, one end of the spring 801 is fixedly connected to one side of the sliding tube 7, and the other end of the spring 801 is fixedly connected to one side of the sleeve 5, which is used to slide the sliding tube 7 and return to the original position under the elastic deformation force of the spring 801.

[0033] Specifically, the joint 4 is threadedly connected to the inside of the threaded groove 3, and the inside of the chromatographic column body 1 is provided with a filler.

[0034] Specifically, the protection column body 11 is inserted with a column core 13, and the column core 13 is matched in size with the protection column body 11.

[0035] Specifically, one side of the protection column body 11 is provided with a threaded hole, and the threaded hole is threadedly connected to an external liquid inlet interface.

[0036] The working principle and use process of the utility model: hold the sliding pipe 7 and pull outward, the sliding pipe 7 drives spring 801 to move and change, insert the pipe joint 10 into the inside of the sleeve pipe 5, the positioning ball 802 is extruded along the annular groove outward when the pipe joint 10 inserts the bottom of the sleeve pipe 5, and the positioning ball 802 moves to the fixed groove of the pipe joint 10, loosen the sliding pipe 7, the sliding pipe 7 returns to the original position under the action of the elastic deformation of spring 801, the positioning ball 802 is extruded along the annular groove inward by the sleeve pipe 7, and the positioning ball 802 buckles into the fixed groove of the pipe joint 10, at this time, the sleeve pipe 5 and the pipe joint 10 buckle and connect together.

[0037] When the connecting port 2 is threadedly connected with the joint 4, the water stop rod 903 abuts against the internal filler of the chromatographic column, the water stop rod 903 moves towards the protective column and pushes the water stop joint 901 away from the outlet of the sleeve pipe 5, and the liquid inlet 902 is exposed so that the sample liquid can flow, when the connecting port 2 and the joint 4 are disconnected, the water stop joint 901 moves towards the outlet of the sleeve pipe 5 under the action of the sample liquid flow, and the liquid inlet 902 is blocked so that the sample liquid cannot flow out.

[0038] The pressure sensor 1203 is used for monitoring the pressure when the sample liquid flows in the protective column main body 11, when the internal precipitate of the column core 13 is too much, the pressure value rises, the controller 1205 controls the alarm indicator light to alarm and prompt the staff to clean or replace in time, so as to prevent the influence on the filtering effect, so as to affect the stability and reproducibility of the chromatographic analysis.

[0039] In summary, the inlet protective column device of the chromatographic column, by setting the pressing mechanism 8 arranged on one side of the sliding pipe 7 and the water stop mechanism 9 arranged in the inside of the sleeve pipe 5, when the column core 13 is replaced, the screw does not need to be twisted and directly buckled and disassembled, and the problem that the sample liquid flows out caused by the disconnection of the protective column and the chromatographic column is effectively avoided, the operation steps are simplified, the staff can save time and energy, the work task can be completed faster, and the productivity is improved, by setting the monitoring mechanism 12 arranged on the surface of the protective column main body 11, the column core 13 can be cleaned or replaced in time, and the stability and flow rate control when the sample liquid flows into the chromatographic column are ensured.

[0040] It should be noted that in this document, such as the term "include", "contain" or any other variant thereof is intended to cover non-exclusive inclusion, so that the process, method, article or equipment including a series of elements not only includes those elements, but also includes other elements not explicitly listed, or includes the elements inherent in such process, method, article or equipment. Without more limitations, the element defined by the statement "including a" does not exclude the existence of other identical elements in the process, method, article or equipment including the element.

[0041] Although the embodiments of the present application have been shown and described, it is to be understood that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An inlet guard column device of a chromatographic column, comprising a chromatographic column body (1) and a connecting port (2) arranged on one side of the chromatographic column body (1), characterized in that, Also includes: The threaded groove (3) is arranged in the connecting port (2), the threaded groove (3) is internally threaded with the joint (4), one side of the joint (4) is fixedly connected with the sleeve (5), the inside of the sleeve (5) is provided with a sealing ring (6), the surface of the sleeve (5) is sleeved with a sliding tube (7), one side of the sliding tube (7) is fixedly connected with a pressing mechanism (8), the pressing mechanism (8) comprises a spring (801) and a positioning ball (802); The water stop mechanism (9) is arranged in the sleeve (5), the water stop mechanism (9) comprises a water stop joint (901), a liquid inlet (902) and a water stop rod (903); The pipeline joint (10) is arranged in the sleeve (5), the surface of the pipeline joint (10) is provided with a fixed groove, one side of the pipeline joint (10) is fixedly connected with a protection column body (11), the surface of the protection column body (11) is fixedly connected with a monitoring mechanism (12), the monitoring mechanism (12) comprises a pressure gauge (1201), a battery (1202), a pressure sensor (1203), an alarm indicator (1204) and a controller (1205).

2. An inlet guard column device for a chromatographic column as defined in claim 1, characterized in that: The spring (801) is fixedly connected to one side of the sliding tube (7), the surface of the sleeve (5) is provided with six positioning balls (802), the surface of the positioning ball (802) is provided with an annular groove, and the positioning ball (802) is clamped to the side surface of the sleeve (5).

3. An inlet guard column device for a chromatographic column as defined in claim 1, characterized in that: The water stop joint (901) is inserted into the inside of the sleeve (5), the surface of the water stop joint (901) is provided with two liquid inlets (902), and the inside of the water stop joint (901) is fixedly connected with a water stop rod (903).

4. An inlet guard column apparatus for a chromatographic column as defined in claim 1, characterized in that: The pressure gauge (1201) is fixedly connected to the surface of the protection column body (11), one side of the pressure gauge (1201) is electrically connected with the battery (1202) through the power line, one side of the battery (1202) is electrically connected with the pressure sensor (1203) through the power line, one side of the pressure sensor (1203) is electrically connected with the alarm indicator (1204) through the power line, and one side of the alarm indicator (1204) is electrically connected with the controller (1205) through the power line.

5. An inlet guard column apparatus for a chromatographic column as defined in claim 1, characterized in that: The spring (801) is located on the surface of the sleeve (5), and one end of the spring (801) is fixedly connected to one side of the sleeve (5).

6. An inlet guard column apparatus for a chromatographic column as defined in claim 1, characterized in that: The joint (4) is threadedly connected in the threaded groove (3), and the inside of the chromatographic column body (1) is provided with a filler.

7. An inlet guard column apparatus for a chromatographic column as defined in claim 1, characterized in that: The inside of the protection column body (11) is inserted with a column core (13), and the column core (13) is matched in size with the protection column body (11).

8. An inlet guard column apparatus for a chromatographic column as defined in claim 1, characterized by: One side of the protection column body (11) is provided with a threaded hole, and the threaded hole is threadedly connected to the external liquid inlet interface.

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